Academic literature on the topic 'Non-pareil Seeds'

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Journal articles on the topic "Non-pareil Seeds"

1

Sailesh, G., and T. E. G. K. Murthy. "FORMULATION AND OPTIMIZATION OF TELMISARTAN MULTIPARTICULATE SYSTEM USING A 22 FACTORIAL DESIGN." INDIAN DRUGS 49, no. 03 (2012): 47–51. http://dx.doi.org/10.53879/id.49.03.p0047.

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Telmisartan is used in the treatment of hypertension. It exhibits poor water solubility. It belongs to class II of Biopharmaceutical Classification system (BCS). It needs enhancement in dissolution and hence bioavailability. The dissolution of drug was improved by coating the drug and carrier over sugar spheres.Size of sugar spheres and concentration of the carrier were two critical variables that were found to affect the dissolution of drug. A 22 factorial design was used to study the effect of concentration of carrier and size of the non-pareil seeds on dissolution. Dissolution of telmisarta
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2

Boles, M. G., P. B. Deasy, and M. F. Donnellanj. "Microencapsulation studies on aminophylline involving spherical crystallization, spheronization and drug loading on to non-pareil seeds." Journal of Microencapsulation 11, no. 1 (1994): 55–67. http://dx.doi.org/10.3109/02652049409040438.

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3

Pandit, Ashlesha Pravin, and Rajendra Dattatray Shinde. "Development and in vitro evaluation of sustained release multiparticulate tablet of freely water soluble drug." Brazilian Journal of Pharmaceutical Sciences 46, no. 3 (2010): 463–71. http://dx.doi.org/10.1590/s1984-82502010000300009.

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Blends of aqueous dispersion of a hydrophobic and hydrophilic polymer, namely Surelease®: hydroxypropyl methylcellulose (Surelease®: HPMC E15) were used as coating materials to control the drug release from coated pellets of the highly water soluble drug metoprolol succinate. Varying the polymer blends, ranges of drug release patterns were obtained at pH 6.8. The present study dealt with diffusion of drug through plasticized Surelease®/ hydroxypropyl methylcellulose (HPMC E15) films prepared by coating of drug and polymers onto non-pareil seeds using the solution layering technique. The releas
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4

Anisha, Kohale Dr. A. V. Chandewar Dr. S. R. Gawande Abhay Dhakare Anjali Bhansali Ashwini Warankar. "Formulation And Evaluation of Pellets." International Journal of Pharmaceutical Sciences 3, no. 5 (2025): 2582–91. https://doi.org/10.5281/zenodo.15429349.

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The present study focuses on the formulation and evaluation of Esomeprazole-coated sustained release pellets using various polymers in different ratios. Esomeprazole, a proton pump inhibitor, is acid-labile and requires protection from gastric acid for effective intestinal absorption. In this research, non-pareil (NP) seeds were prepared using the extrusion-spheronization process and subsequently coated with Esomeprazole and sustained release polymers through the pan coating method. Various polymer ratios were applied to assess their effect on drug release behavior. The formulated pellets were
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5

B., Ranjith Kumar* Santhosh Illendula P. Shyam Sundar G. Guna Sheela Nadimenti Mogulaiah. "DEVELOPMENT OF MULTIPARTICULATE SYSTEM OF MEBEVERINE HYDROCHLORIDE FOR THE TREATMENT OF IRRITABLE BOWEL SYNDROME." INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES 05, no. 02 (2018): 1013–19. https://doi.org/10.5281/zenodo.1183928.

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Pellets were witnessed as one of the promising modified drug delivery systems widely employed now-a-days in the management of various diseases. Mebeverine hydrochloride pellets were coated by suspension layer technique using fluidized bed processor (FBP). This method applied found to be effective to coat the drug uniformly onto the non-pareil (NP) seeds. In this study, three coatings viz., binder (PVP K30), barrier (EC 5 cps) and sustained release (EC 3 cps and HPMC 10 cps) were applied. At each stage of coating, optimized formulation was found out for next subsequent coating and they were F4,
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6

Goparaju, Suryanarayana Murthy. "Formulation and In-Vitro Evaluation of immediate-release pellets of Candesartan Cilexetil." January 18, 2021. https://doi.org/10.26452/fjphs.v1i1.3.

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Multi particulate drug delivery system has long run also been made use of to enhance the overall bioavailability going from drugs having low aqueous solubility. Candesartan Cilexetil is an anti-hypertensive drug. Complex and dispersion of Candesartan Cilexetil with the different carriers were prepared to increase its solubility and bioavailability. Due to its low aqueous solubility bioavailability of the drug is 15 % and it shows variable absorption from GIT. Pellets offer several advantages such as proper distribution in the GIT tract, reduces dose dumping, and relief going from administratio
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