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Journal articles on the topic 'Non-Proliferative Diabetic'

Author: Grafiati

Published: 5 June 2025

Last updated: 2 August 2025

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1

Varma, Nandini, and Sinumol Thulaseedharan. "Study on Risk Factors Associated with Severity of Diabetic Retinopathy in Type-2 Diabetic Patients, Attending a Tertiary Care Centre in Kerala." International Journal of Research and Review 10, no. 11 (2023): 143–47. http://dx.doi.org/10.52403/ijrr.20231116.

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Introduction: Diabetic retinopathy (DR) is a significant public health concern affecting individuals with diabetes mellitus (DM). Despite treatment advances, a substantial proportion of patients do not respond adequately. This study investigates risk factors associated with the progression of non-proliferative diabetic retinopathy (NPDR) to proliferative diabetic retinopathy (PDR) in type-2 diabetes patients. Methods: A retrospective case-control study was conducted on diabetic patients older than 40 years with at least 5 years of Type-2 Diabetes Mellitus history, attending ophthalmology clini

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Danek, Dagmara, Brian Larsen, and Susan Anderson-Nelson. "Non-proliferative diabetic retinopathy." Disease-a-Month 67, no. 5 (2021): 101139. http://dx.doi.org/10.1016/j.disamonth.2021.101139.

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3

Mohammad Alam. "Diabetic retinopathy in diabetic patients versus diabetic with co-morbid hypertensive patients." Professional Medical Journal 29, no. 07 (2022): 1041–44. http://dx.doi.org/10.29309/tpmj/2022.29.07.6861.

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Objectives: To find out severity of diabetic retinopathy in diabetic versus diabetic with co-morbid hypertensive patients in type II diabetes mellitus. Study Design: Comparative study. Setting: KDA Teaching Hospital Kohat. Period: March 2017 to December 2020. Material & Methods: This comparative study focused on severity of diabetic retinopathy was conducted on only type II diabetic patients versus type II diabetic with co-morbid hypertensive patients. Two groups A for diabetic and B for diabetic with co-morbid hypertension patients were made. Proper proforma of diabetic age and severity o

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Zhou, Amy Y., Brooklyn E. Taylor, Katherine G. Barber, et al. "Anti-IL17A Halts the Onset of Diabetic Retinopathy in Type I and II Diabetic Mice." International Journal of Molecular Sciences 24, no. 2 (2023): 1347. http://dx.doi.org/10.3390/ijms24021347.

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There are ~463 million diabetics worldwide, and more than half have diabetic retinopathy. Yet, treatments are still lacking for non-proliferative diabetic retinopathy. We and others previously provided evidence that Interleukin-17A (IL-17A) plays a pivotal role in non-proliferative diabetic retinopathy. However, all murine studies used Type I diabetes models. Hence, it was the aim of this study to determine if IL-17A induces non-proliferative diabetic retinopathy in Type II diabetic mice, as identified for Type I diabetes. While examining the efficacy of anti-IL-17A as a potential therapeutic

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Malaguarnera, Giulia, Caterina Gagliano, Maria Giordano, et al. "Homocysteine Serum Levels in Diabetic Patients with Non Proliferative, Proliferative and without Retinopathy." BioMed Research International 2014 (2014): 1–4. http://dx.doi.org/10.1155/2014/191497.

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Homocysteine has been associated with extracellular matrix changes. The diabetic retinopathy is a neurovascular complication of diabetes mellitus and it is the leading cause of vision loss among working adults worldwide. In this study, we evaluate the role of homocysteine in diabetic retinopathy analyzing the plasma levels of homocysteine in 63 diabetic type 2 patients with nonproliferative retinopathy (NPDR), 62 patients with proliferative diabetic retinopathy (PDR), 50 healthy subjects used as control group, and 75 randomly selected patients.

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Dr., Mahfooz Alam. "Serum Levels of Vitamin D in Patients of Diabetic Retinopathy at a Tertiary Level in North India." International Journal of Medical and Pharmaceutical Research 4, no. 3 (2023): 890–32. https://doi.org/10.5281/zenodo.8098539.

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<strong>Introduction</strong>: Diabetic retinopathy is a major complication of diabetes mellitus that can result in retinal vascular abnormalities and severe visual impairment. Vitamin D deficiency is involved in impaired glucose tolerance or type-2 diabetes. Vitamin D may affect the pathogenesis of diabetic retinopathy via its effects on angiogenesis by changing the presence of hypoxia inducible products, such as vascular endothelial growth factor. <strong>Study design</strong>: It was cross-sectional study done at a tertiary centre in North India. <strong>Results</strong>: In the Non prolife

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7

Li, Shipeng, Jianling Sun, Wenchao Hu, et al. "The association of serum and vitreous adropin concentrations with diabetic retinopathy." Annals of Clinical Biochemistry: International Journal of Laboratory Medicine 56, no. 2 (2019): 253–58. http://dx.doi.org/10.1177/0004563218820359.

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Objective Adropin, a newly identified regulatory protein encoded by Enho gene, is correlated with insulin sensitivity and diabetes. The aim of this study is to determine whether serum and vitreous adropin concentrations are correlated with the presence of diabetic retinopathy. Methods A population of 165 patients with type 2 diabetes mellitus (52 without diabetic retinopathy, 69 with non-proliferative diabetic retinopathy and 44 patients with proliferative diabetic retinopathy) was enrolled in this study. The control group enrolled 68 healthy subjects who had underwent vitrectomy for retinal d

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8

Zhang, Xiao, Neelam Kumari, Serena Low, et al. "The association of serum creatinine and estimated glomerular filtration rate variability with diabetic retinopathy in Asians with type 2 diabetes: A nested case–control study." Diabetes and Vascular Disease Research 15, no. 6 (2018): 548–58. http://dx.doi.org/10.1177/1479164118786969.

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Background: Fluctuation of kidney function may signify intra-glomerular microvascular hemodynamic instability. We aim to examine the association of long-term serum creatinine and estimated glomerular filtration rate variability with diabetic retinopathy. Methods: We included type 2 diabetes mellitus patients who attended the Diabetes Centre in 2011–2014 and were followed up (median = 3.2 years). Digital colour fundus photographs were assessed for diabetic retinopathy at follow-up. Diabetic retinopathy severity was categorized into non-proliferative diabetic retinopathy and proliferative diabet

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Zhang, Xiao, Su Chi Lim, Subramaniam Tavintharan, et al. "Association of central arterial stiffness with the presence and severity of diabetic retinopathy in Asians with type 2 diabetes." Diabetes and Vascular Disease Research 16, no. 6 (2019): 498–505. http://dx.doi.org/10.1177/1479164119845904.

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Objective: Arterial stiffness has been associated with diabetic retinopathy; however, the information is limited in Asians. We aim to examine the association of central arterial stiffness with the presence and severity of diabetic retinopathy in type 2 diabetes mellitus patients in Singapore. Methods: Arterial stiffness was estimated by carotid-femoral pulse wave velocity and augmentation index using applanation tonometry method. Digital colour fundus photographs from 1,203 patients were assessed for diabetic retinopathy. Diabetic retinopathy severity was categorized into non-proliferative dia

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Shinde, Pranaykumar. "Study of Retinal Nerve Fibre Layer Thickness in Diabetics - with and without Diabetic Retinopathy." Journal of Evolution of Medical and Dental Sciences 10, no. 31 (2021): 2427–32. http://dx.doi.org/10.14260/jemds/2021/497.

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BACKGROUND Diabetes mellitus is a heterogeneous group of diseases, characterized by a state of chronic hyperglycemia, resulting from varied aetiologies. Diabetic retinopathy (DR) is the most common ocular complication of diabetes with 5 % of diabetics, progressing to severe visual loss of 5/200 or less. 3 Very few studies have been conducted on optical coherence tomography (OCT) changes in diabetic retinopathy in Indian scenario. We wanted to evaluate the association of retinal nerve fibre layer (RNFL) thickness with diabetic retinopathy and assess the possibility of RNFL thickness changes bei

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Chowdhury, Farah Diba, Mirza Omar Beg, Nusrath Jahan Chowdhury, Barsha Mojumder Papri, and Shukdeb Paul. "Association of Renal Functional Status in Different Stages of Diabetic Retinopathy." Medicine Today 37, no. 1 (2025): 114–18. https://doi.org/10.3329/medtoday.v37i1.79438.

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Introduction: Diabetic nephropathy (DN) and diabetic retinopathy (DR) are both complications of diabetic microangiopathy with similar pathogenesis and clinical relevance. Many studies have demonstrated an association between diabetic retinopathy and diabetic nephropathy in type 1 diabetes mellitus (T1DM) patients, but this association is less strong in T2DM. There is link exists between different stages of diabetic retinopathy and diabetic nephropathy in T2DM. Aims and Objective: To explore the renal functional status in different stages of diabetic retinopathy. Materials and Methods: This cro

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Obadă, Otilia, Anca Delia Pantalon, Gabriela Rusu-Zota, et al. "Aqueous Humor Cytokines in Non-Proliferative Diabetic Retinopathy." Medicina 58, no. 7 (2022): 909. http://dx.doi.org/10.3390/medicina58070909.

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Background and Objectives: Cytokines are cell-signaling proteins whose identification may serve as inflammatory markers or early indicators for progressive disease. The aim of our study was to quantify several cytokines in aqueous humor (AH) and their correlations with biochemical parameters in diabetic eyes with non-proliferative diabetic retinopathy (NPDR). Materials and Methods: A total of 62 eyes from 62 patients were included in the study: 37 eyes from nondiabetic patients (group 1), 13 diabetic eyes with no retinopathy changes (group 2) and 12 diabetic eyes with early and moderate NPDR (

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13

Pooja H V and Lakshmi M S. "Role of hyperhomocysteinemia in the progression of diabetic retinopathy." Indian Journal of Clinical and Experimental Ophthalmology 10, no. 1 (2024): 160–63. http://dx.doi.org/10.18231/j.ijceo.2024.028.

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: The aim of this study was to determine the role of hyperhomocysteinemia in the progression of diabetic retinopathy and to determine the association of hyperhomocysteinemia with various grades of diabetic retinopathy.Diabetic retinopathy is the most common ocular complication of Diabetes mellitus. Various studies have shown that mild elevations of homocysteine in plasma are associated with an increased risk of vaso-occlusive disease, thrombosis, and stroke.: A total of 97 patients who were diagnosed with diabetic retinopathy from October 2018 to September 2019 were included in our study. Writ

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Tzekov, R. "EOG changes in non-proliferative and proliferative diabetic retinopathy." Vision Research 35, no. 1 (1995): S214. http://dx.doi.org/10.1016/0042-6989(95)98821-p.

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15

Poshtchaman, Faeze, Alemeh Dehnabi, Zahra Poshtchaman, and Batul Birjandi. "HbA1C, proliferative and non-proliferative retinopathy in diabetic patients." Medicina Clínica Práctica 6, no. 3 (2023): 100371. http://dx.doi.org/10.1016/j.mcpsp.2023.100371.

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16

Anisic, Katarina, and Sofija Davidovic. "Correlation between eye and renal complications of diabetes." Medical review 71, no. 9-10 (2018): 295–99. http://dx.doi.org/10.2298/mpns1810296a.

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Introduction. Complications of diabetes can affect almost all tissues and organs, causing high morbidity, disability and mortality. The aim of this study was to examine eye and kidney disorders of patients with patients with diabetes, and assess the correlation between them. Material and Methods. This retrospective study included 45 patients suffering from type 2 diabetes for more than ten years. The patients were divided into three groups of 15 subjects each: patients without diabetic retinopathy, patients with non-proliferative retinopathy, and patients with proliferative diabetic retinopath

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17

Ali, Farhan, and Syed Nishat Akram. "Frequency of Diabetic Retinopathy in Diabetic Patients in Pakistan." Journal of Contemporary Insights in Health Sciences 1, no. 1 (2023): 23–29. http://dx.doi.org/10.69591/jcihs.v1i1.5.

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Objective: To determine the frequency of diabetic retinopathy and its types in diabetic patients of Pakistan. Study Design: cross sectional study. Place and duration: study was conducted in department of Ophthalmology, Nishtar Hospital Multan from 1st June 2020 to 2nd June 2021 in one-year duration. Methodology: Study was conducted on 300 diabetic patients and presented at the outpatient’s department of hospital. Refraction was done in all patients with the Snellen chart and fundus was examined with slit lamp or fundoscopy method. Main variables of study were diabetic retinopathy, macular edem

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Yusran, Muhammad. "Retinopati Diabetik: Tinjauan Kasus Diagnosis dan Tatalaksana." Jurnal Kedokteran Universitas Lampung 1, no. 3 (2017): 578–62. https://doi.org/10.23960/jkunila.v1i3.pp578-562.

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Diabetes mellitus (DM) dapat menyebabkan komplikasi mikrovaskular berupa retinopati diabetik (RD). Kejadian RD cukup banyak dan dapat menimbulkan kebutaan jika tata laksana tidak adekuat. Tinjauan kasus ini bertujuan untuk menunjukkan pentingnya penegakan diagnosis yang cepat dan tepat melalui skrining, serta beberapa modalitas terapi pada RD. Pasien perempuan dengan penurunan tajam penglihatan secara perlahan sejak 6 bulan disertai timbul bayangan hitam pada matakiri yang makin memberat. Pasien menderitaDM, hipertensi, dan hiperkolesterol. Pasien didiagnosis dengan Proliferative Retinophaty D

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Vikas, Gupta, and Gupta Amit. "Association of Glycosylated Hemoglobin (HBA1C) Level with Diabetic Retinopathy in Type 2 Diabetes Patients at Tertiary Care Hospital." International Journal of Pharmaceutical and Clinical Research 15, no. 5 (2023): 489–94. https://doi.org/10.5281/zenodo.12564006.

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<strong>Introduction: </strong>Diabetic retinopathy (DR) is a chronic progressive, potentially sight-threatening disease of the retinal microvasculature associated with the prolonged hyperglycemia and associated with other condition. HbA1C is an important predictor for early identification of diabetic retinopathy cases. <strong>Materials and Method:</strong> It is a hospital based prospective observational study conducted in the Department of Ophthalmology, Mahatma Gandhi Medical College, Jaipur, Rajasthan, India to assess association of HbA1C levels with Diabetic retinopathy in

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20

Ijeri, Raghavendra K., Mervin Jonathan Israel, and Nikhita Anil Sankolli. "Choroidal thickness in type 2 diabetes mellitus patients using spectral domain optical coherence tomography." Indian Journal of Clinical and Experimental Ophthalmology 10, no. 3 (2024): 475–80. http://dx.doi.org/10.18231/j.ijceo.2024.082.

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To measure the choroidal thickness in patients with type 2 diabetes mellitus and its comparison to healthy age-matched individuals.This prospective comparative study conducted at departments of Ophthalmology, Shri B.M. Patil Medical College, Hospital and Research Centre, Vijayapura. Study included 192 patients, 96 with diabetes and 96 age-matched controls. Data acquired comprised demographics, a thorough eye examination, fundus photography and spectral domain optical coherence tomography measurements of choroidal thickness using enhanced depth imaging.Mean age was 60.17±7.727 years with male p

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Ramakrishnan, Karthik Krishna, Anusha Palani Swamy, Prashant Moorthy, et al. "Role Of Colour Doppler Imaging In Early Diagnosis Of Diabetic Retinopathy." Journal of University of Shanghai for Science and Technology 23, no. 09 (2021): 361–80. http://dx.doi.org/10.51201/jusst/21/09566.

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Diabetic retinopathy is the most common cause of vision loss among people with diabetes and a leading cause of blindness among working-age adults in India. It is a form of microangiopathy, and is the most common ocular complication seen in diabetic patients. Diabetic retinopathy progresses from non proliferative to proliferative retinopathy. The non proliferative retinopathy is the milder form and it is reversible. As the progression to proliferative retinopathy happens, the patients are symptomatic and become irreversible. Vascular changes and subsequent ocular hemodynamic changes are critica

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Farooq, Mashhood, Syed Inamullah, Shama Mashhood, Mahmood Rana, and Muhammad Fahim. "Deficiency of Vitamin D: Influence on Diabetic Retinopathy and Hearing Loss Among Patients with Diabetes Mellitus Type 2." Journal of Bahria University Medical and Dental College 10, no. 4 (2020): 282–86. http://dx.doi.org/10.51985/jbumdc2020068.

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Objective: To find a relationship between serum level of vitamin D with diabetic retinopathy and hearing loss in patients with diabetes mellitus type2. Study design and setting: This cross-sectional study was carried out at Ophthalmology, ENT and family physician Outpatient clinic of Mohsin Consultant Clinic Federal B Area, Karachi from study was April 2019 to December 2019. Methodology: Total 181 eligible type 2 diabetes mellitus patients. Complete ophthalmological, ENT and physical evaluation was carried out. Retinopathy and hearing status were recorded and were compared to serum 25-OH Vitam

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Karimsab, D., and SK Razak. "Study of aerobic bacterial conjunctival flora in patients with diabetes mellitus." Nepalese Journal of Ophthalmology 5, no. 1 (2013): 28–32. http://dx.doi.org/10.3126/nepjoph.v5i1.7818.

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Introduction: Normal bacterial flora may be altered by a variety of factors. Objective: To study the aerobic bacterial conjunctival flora in patients with diabetes mellitus and to find its clinical significance by comparing the results to the conjunctival flora of non-diabetic subjects. Materials and methods: A total of 75 diabetic patients were included as cases and 25 nondiabetics as controls to compare the results. Specimens for the study of conjunctival flora were taken by rubbing sterile cotton-tipped swabs to the inferior palbebral conjunctiva. The conjunctival culture report of the pati

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Bibi Rafeen Talpur, Hanozia Hassan, Yar Muhammad Nizamani, Safdar Ali Abbasi, Sidra Binte Saleem, and Kishwar. "Analysis of intraocular pressure in healthy individuals and type 2 diabetes patients with and without diabetic retinopathy: A comparative study." Professional Medical Journal 30, no. 09 (2023): 1113–23. http://dx.doi.org/10.29309/tpmj/2023.30.09.7562.

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Objective: To compare intraocular pressure between normal subjects and Type 2 diabetics with and without diabetic retinopathy. Study Design: Comparative study. Setting: Sindh Institute of Ophthalmology & Visual Sciences Hyderabad Sindh Pakistan. Period: June 2021 to December 2021. Material & Methods: The ages ranged from 45 to 75 years old. The blood glucose level, intraocular pressure, and indirect ophthalmoscopy were measured between 9:00 am and 11:00 am with an iCare tonometer and an ophthalmoscope. The data were analyzed in SPSS 23.0. Results: A total of 112 participants were inclu

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Zapadka, Thomas E., Sarah I. Lindstrom, Julia C. Batoki, et al. "Aryl Hydrocarbon Receptor Agonist VAF347 Impedes Retinal Pathogenesis in Diabetic Mice." International Journal of Molecular Sciences 22, no. 9 (2021): 4335. http://dx.doi.org/10.3390/ijms22094335.

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Diabetic retinopathy is the leading cause of blindness in the working-age population worldwide. Although the cause of diabetic retinopathy is multifactorial, IL-17A is a prevalent inflammatory cytokine involved in the promotion of diabetes-mediated retinal inflammation and the progression of diabetic retinopathy. The primary source of IL-17A is Th17 cells, which are T helper cells that have been differentiated by dendritic cells in a proinflammatory cytokine environment. Aryl hydrocarbon receptor (AhR) is a ligand-dependent transcription factor that can manipulate dendritic cell maturation, ha

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Javed, Muhammad Nasir, Mohsina Noor Ibrahim, Zubair Khoso, Ikramullah v, Maira Riaz, and Versha Rani Rai. "Frequency and Risk Factors of Diabetic Retinopathy in Children having Type-1 Diabetes Mellitus." National Journal of Health Sciences 9, no. 4 (2024): 271–76. https://doi.org/10.21089/njhs.94.0271.

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Abstract: Background: Diabetic retinopathy is the most prevalent complication and the primary cause of blindness in people with type 1 diabetes mellitus. There are two categories of risk factors: modifiable and non-modifiable for development of diabetic retinopathy. Objective: To determine the frequency and risk factors of diabetic retinopathy in children having type-1 diabetes mellitus. Materials and Methods: Children aged 7 to 18 years participated in this cross-sectional study, which was carried out in the National Institute of Child Health’s endocrinology department. Clinical, anthropometr

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Smith, S. "Non proliferative diabetic retinopathy and macular edema." Insight - the Journal of the American Society of Ophthalmic Registered Nurses 24, no. 2 (1999): 59–62. http://dx.doi.org/10.1016/s1060-135x(99)90012-x.

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Deák, Mónika, Monica Lasca, and Ioan Andrei Vereşiu. "Risk Factors For Diabetic Retinopathy Progression." Romanian Journal of Diabetes Nutrition and Metabolic Diseases 22, no. 2 (2015): 159–65. http://dx.doi.org/10.1515/rjdnmd-2015-0020.

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AbstractBackground and Aims. There is no unanimous opinion regarding the risk factors associated with progression of diabetic retinopathy (DR). We have done a retrospective analysis of risk factors and clinical features associated with DR progression.Material and Methods. This analysis included consecutive patients with moderate non-proliferative or severe retinopathy between December 1, 2013 and May 31, 2014 who had at least two eye examinations before that period. We have collected demographic, clinical and lab data.Results. 51.28% of patients were diagnosed with moderate non-proliferative d

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Chowhan, Santosh S., Rakesh S. Deore, and Sachin A. Naik. "Retinal Vessel Segmentation of Non-Proliferative Diabetic Retinopathy." International Journal of Applied Evolutionary Computation 10, no. 1 (2019): 30–38. http://dx.doi.org/10.4018/ijaec.2019010102.

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Diabetic retinopathy is a disease in diabetic patients that affects the eye. It happens due to damage in the blood vessels of the light-sensitive tissues at the retina. In non-proliferative diabetic retinopathy, tiny changes occur in the blood vessels of the eye. Non-proliferative diabetic retinopathy can trigger macular edema or macular ischemia. In this study proposes the retinal vessel segmentation and vessel quantization on the DRIVE database which is publicly available. The experimental results express the retinal vessel can be effectively detected and segmented.

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Mani, Koushiki, and Rose Davy C. "Prevalence of diabetic retinopathy in type 2 diabetes mellitus patients attending medicine out-patient department of a tertiary care hospital in Alappuzha, Kerala, India." International Journal of Research in Medical Sciences 5, no. 4 (2017): 1532. http://dx.doi.org/10.18203/2320-6012.ijrms20171259.

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Background: Diabetic retinopathy is a microvascular complication affecting the eyes of both Type 1 and Type 2 diabetes mellitus due to long-term hyperglycaemia. Diabetic retinopathy is the leading cause of blindness among working aged adults around the world. There are various factors leading to the development of diabetic retinopathy namely duration of diabetes, glycaemic control, age at onset of diabetes, uncontrolled hypertension. This is a hospital based cross-sectional study which aimed to study the prevalence of diabetic retinopathy in type 2 diabetes mellitus patients attending Medicine

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Ofuji, Yoshiko, Yusaku Katada, Yohei Tomita, et al. "Non-Perfusion Area Index for Prognostic Prediction in Diabetic Retinopathy." Life 12, no. 4 (2022): 542. http://dx.doi.org/10.3390/life12040542.

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Fundus fluorescent angiography is a standard examination in Japan that can directly visualize the circulatory failure in diabetic retinopathy but is not used in Western countries. In this study, we examine the relationship between the non-perfusion area in fundus fluorescent angiography and the progression of diabetic retinopathy. We evaluated 22 eyes between 22 patients who had their first fundus fluorescent angiography during a clinical episode at Keio University Hospital from January 2012 to May 2015, were diagnosed as having preproliferative diabetic retinopathy, and could be followed for

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Grzybowski, Andrzej, Piotr Kanclerz, Valentín Huerva, Francisco J. Ascaso, and Raimo Tuuminen. "Diabetes and Phacoemulsification Cataract Surgery: Difficulties, Risks and Potential Complications." Journal of Clinical Medicine 8, no. 5 (2019): 716. http://dx.doi.org/10.3390/jcm8050716.

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Diabetes mellitus is one of the most prevalent chronic diseases worldwide. Diabetic patients are at risk of developing cataract and present for surgery at an earlier age than non-diabetics. The aim of this study was to review the problems associated with cataract surgery in a diabetic patient. Corneal complications in diabetic patients include delayed wound healing, risk of developing epithelial defects or recurrent erosions due to the impairment of epithelial basement membranes and epithelial–stromal interactions. Diabetic patients present lower endothelial cell density and their endothelium

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Tzekov, R., and V. Tanev. "P 339 EOG changes in non-proliferative and proliferative diabetic retinopathy." Vision Research 35 (October 1995): S214. http://dx.doi.org/10.1016/0042-6989(95)90599-5.

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Tănasie, Cornelia Andreea, Alexandra Oltea Dan, Oana Maria Ică, et al. "Retinal Functional Impairment in Diabetic Retinopathy." Biomedicines 12, no. 1 (2023): 44. http://dx.doi.org/10.3390/biomedicines12010044.

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Background: Diabetic retinopathy (DR) is a neurodegenerative disease of the retina. The aim of our study was to analyze latency changes in a full-field electroretinogram (ERG) in patients with type 2 diabetes. Material: This prospective study included 15 diabetic patients without DR, 16 diabetic patients with non-proliferative DR, 14 patients with pre-proliferative DR, 15 patients with proliferative DR, and 14 age-matched controls. All the participants underwent ophthalmologic examination and full-field ERGs. The ERGs were recorded with the Metrovision MonPackOne system. The latencies were ana

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Yefrenes Dillak, Rocky, and Agus Harjoko. "Klasifikasi Fase Retinopati Diabetes Menggunakan Backpropagation Neural Network." IJCCS (Indonesian Journal of Computing and Cybernetics Systems) 7, no. 1 (2013): 23. http://dx.doi.org/10.22146/ijccs.3049.

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AbstrakRetinopati diabetes (DR) merupakan salah satu komplikasi pada retina yang disebabkan oleh penyakit diabetes. Tingkat keparahan DR dibagi atas empat kelas yakni: normal, non-proliferative diabetic retinopathy (NPDR), proliferative diabetic retinopathy (PDR), dan macular edema (ME). Penelitian ini bertujuan mengembangkan suatu metode yang dapat digunakan untuk melakukan klasifikasi terhadap fase DR. Data yang digunakan sebanyak 97 citra yang fitur – fiturnya diekstrak menggunakan gray level cooccurence matrix (GLCM). Fitur ciri tersebut adalah maximum probability, correlation, contrast, e

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Zaman, Mohammad Shiblee, Md Matiur Rahman, Subrata Kumar Biswas, Md Mozammel Hoque, and Khondakar Alwan Nahid. "Association of serum vitamin D and parathormone levels in patients of type 2 diabetes mellitus with diabetic retinopathy." Bangabandhu Sheikh Mujib Medical University Journal 10, no. 2 (2017): 61. http://dx.doi.org/10.3329/bsmmuj.v10i2.32287.

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<p>The present study was aimed to evaluate the association of serum 25-hydroxy vitamin D and parathormone in 46 patients of type 2 diabetes mellitus with diabetic retinopathy [non-proliferative, (n=27); proliferative (n=19)]. Twenty one diabetic patients without retinopathy were taken as control. Serum 25-hydroxy vitamin D and intact parathyroid hormone were measured by chemiluminescence microparticle immunoassay. Concentration of 25-hydroxy vitamin D differed significantly among groups (p=0.018) and it was significantly lower in proliferative diabetic retinopathy than no diabetic retino

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Tsai, Teresa, Mohannad Alwees, Mohammad Ali Asaad, et al. "Increased Angiopoietin-1 and -2 levels in human vitreous are associated with proliferative diabetic retinopathy." PLOS ONE 18, no. 1 (2023): e0280488. http://dx.doi.org/10.1371/journal.pone.0280488.

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Background Diabetic retinopathy is a frequent complication of diabetes mellitus and a leading cause of blindness in adults. The objective of this study was to elucidate the diabetic retinopathy pathophysiology in more detail by comparing protein alterations in human vitreous of different diabetic retinopathy stages. Methods Vitreous samples were obtained from 116 patients undergoing pars plana vitrectomy. Quantitative immunoassays were performed of angiogenic factors (VEGF-A, PIGF, Angiopoietin-1, Angiopoietin-2, Galectin-1) as well as cytokines (IL-1β, IL-8, IFN-γ, TNF-α, CCL3) in samples fro

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Maulida, Rizka Ayu, and Fiza Afifah. "Diabetic Retinopathy: A Literature Review." Jurnal Biologi Tropis 24, no. 4 (2024): 188–92. https://doi.org/10.29303/jbt.v24i4.7589.

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Diabetic retinopathy is a complication of diabetes mellitus characterized by visual impairment and potentially blindness. This literature review aims to enhance knowledge about diabetic retinopathy. Sources for this review were gathered through online databases and include review articles, research studies, and professional guidebooks related to the topic. Hyperglycemic conditions associated with diabetes mellitus trigger angiogenesis and inflammatory pathways, leading to diabetic retinopathy. The condition is classified into two types: non-proliferative diabetic retinopathy and proliferative

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Arshad, Dhukka, Kejriwal Amrit, and Awais Farooqui Mohammad. "Newly Diagnosed Diabetic Retinopathy in Know Type 2 Diabetic Patients." International Journal of Pharmaceutical and Clinical Research 16, no. 7 (2024): 1476–82. https://doi.org/10.5281/zenodo.13245382.

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<strong>Background:</strong> Diabetic retinopathy (DR) is a significant microvascular complication of type 2 diabetes mellitus (T2DM), leading to vision impairment if untreated. With diabetes prevalence rising globally, including India, early detection and management of DR are critical to prevent severe outcomes. This study aims to evaluate the prevalence of newly diagnosed DR among T2DM patients and its association with disease duration and glycemic control. <strong>Methods:</strong> A cross-sectional observational study was conducted over one month, involving 100 T2DM patients

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Rashad Qamar, Rao Muhammad, Sadiq Hussain Hussain, and Rao Muhammad Aslam Tariq. "DIABETIC RETINOPATHY." Professional Medical Journal 23, no. 05 (2016): 571–75. http://dx.doi.org/10.29309/tpmj/2016.23.05.1585.

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Objectives: The purpose of this study was to evaluate the prevalence andcharacteristics of diabetic retinopathy (DR) in patients attending the free eye camps for cataractsurgery held in southern Punjab, Pakistan. Study Design: It was a cross sectional study. Setting:Free eye camps organized in different regions of the Southern Punjab, Pakistan. Period: July2004 to June 2015. Material and methods: These community-based eye camps were held bythe Department of Ophthalmology in collaboration of department of Pathology, B.V. Hospital,Bahawalpur, Pakistan. Participants were interviewed and examined

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Demidova, Tatiana Yul'evna, and Yulia Alexandrovna Trakhtenberg. "Alpha-lipoic acid in non-proliferative diabetic retinopathy treatment." Diabetes mellitus 14, no. 4 (2011): 82–86. http://dx.doi.org/10.14341/2072-0351-5823.

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Aim. The aim of this study is to assess the therapeutic efficacy of alpha-lipoic acid in patients with type 2 diabetes mellitus (DM) and non-proliferativediabetic retinopathy. Materials and methods. 47 patients with mild to moderate non-proliferative diabetic retinopathy were included in this trial. Dynamics of ophthalmologicparameters were assessed by means of stereoscopic photography of ocular fundus. Patients were examined every 6 months in order to registernew cases of clinically significant macular oedema. Results. During 24 months follow-up period, patients treated with 600 mg of alpha-l

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Reddy, SC, YM Khin, MI Nurjahan, and A. Ramli. "Retinopathy in type 2 diabetic patients with microalbuminuria." Nepalese Journal of Ophthalmology 5, no. 1 (2013): 69–74. http://dx.doi.org/10.3126/nepjoph.v5i1.7830.

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Objective: To determine the prevalence of retinopathy in type 2 diabetic patients with micoalbuminuria and to evaluate the association of risk factors with prevalence of retinopathy in these patients. Material and methods: A fundus examination of 137 patients suffering from type 2 diabetes mellitus with microalbuminuria was done, with direct ophthalmoscope/ binocular indirect ophthalmoscope after dilating the pupils with 1 % tropicamide eye drops. Retinal changes were graded as no retinopathy, non-proliferative retinopathy, proliferative retinopathy and maculopathy. The association of the dura

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Yusran, Muhammad. "EVALUATION OF PANRETINA PHOTOCOAGOLATION TREATMENT IN DIABETIC RETINOPATHY PATIENTS IN RSUD DR. H. ABDUL MOELOEK." Unram Medical Journal 12, no. 1 (2023): 1315–18. http://dx.doi.org/10.29303/jku.v12i1.867.

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Latar belakang: Laser fotokoagulasi retina merupakan tatalaksana utama pada retinopati diabetik. Penelitian ini bertujuan untuk menilai hasil tatalaksana laser fotokoagulasi pada pasien Non Proliferative Diabetic Retinopathy(NPDR) berat dan Proliferative Diabetic Retinopathy(PDR).  Metode: Penelitian potong lintang dengan subyek pasien retinopati diabetik di RSUD dr. H. Abdul Moeloek yang dilakukan laser fotokoagulasi retina lengkap. Penilaian dilakukan terhadap tajam penglihatan dan stabilitas penyakit. Analisis statistik non parametrik menggunakan uji chi-square.  Has

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Lim, Marcus CC, Shu Yen Lee, Bobby CL Cheng, et al. "Diabetic Retinopathy in Diabetics Referred to a Tertiary Centre from a Nationwide Screening Programme." Annals of the Academy of Medicine, Singapore 37, no. 9 (2008): 753–59. http://dx.doi.org/10.47102/annals-acadmedsg.v37n9p753.

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Introduction: The aim of the study was to describe the prevalence and risk factors for diabetic retinopathy in a multi-ethnic diabetic patient cohort referred for retinal evaluation from a nationwide diabetic retinopathy screening programme in Singapore. Materials and Methods: Seven hundred and forty-two patients, aged 21 to 95, referred for suspected diabetic retinopathy on annual one-field non-mydriatic 45 degree retinal photographs (Topcon TRC-NW6, Topcon Corporation, Tokyo, Japan) from primary care to the Singapore National Eye Centre diabetic retinopathy clinic were included. The photogra

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Sirin, Fevziye Burcu, Hakan Korkmaz, Bora Torus, Mustafa Bozkurt, and Duygu Kumbul Doguc. "The role of zonulin in the pathogenesis of diabetic retinopathy." Turkish Journal of Biochemistry 46, no. 3 (2021): 317–22. http://dx.doi.org/10.1515/tjb-2020-0575.

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Abstract Objectives To evaluate serum levels of zonulin and interleukin 6 (IL-6) in type 2 diabetes mellitus (T2DM) patients complicated by diabetic retinopathy and to investigate the effect of intestinal permeability on diabetic retinopathy (DR) progression. Materials and Methods Eighty-nine patients with T2DM and 30 healthy controls aged between 18 and 80 years were enrolled. T2DM patients were grouped as without DR (n=30), with non-proliferative DR (n=29), and with proliferative DR (n=30). Serum zonulin and IL-6 levels were measured with the ELISA method. Results Zonulin levels showed no st

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Thapa, Raba, Sanjita Sharma, Eli Pradhan, Sushma Duwal, and Govinda Paudyal. "Clinical Characteristics of Proliferative Diabetic Retinopathy and Outcome of Pars Plana Vitrectomy in Proliferative Diabetic Retinopathy." Journal of Nepal Health Research Council 22, no. 01 (2024): 157–62. http://dx.doi.org/10.33314/jnhrc.v22i01.4958.

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Background: Proliferative diabetic retinopathy is a leading cause of blindness among people with diabetes. The study aimed to assess the clinical characteristics of proliferative diabetic retinopathy and outcome of pars plana vitrectomy in Proliferative diabetic retinopathy. Methods: A prospective study was conducted from September 2019 to December 2021 among consecutive cases of proliferative diabetic retinopathy who underwent pars plana vitrectomy at a tertiary eye care center. Study was conducted after ethical approval from Institutional Review Committee. Detailed systemic and ocular histor

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Triebel, Jakob, Michael Huefner, and Giuliano Ramadori. "Investigation of prolactin-related vasoinhibin in sera from patients with diabetic retinopathy." European Journal of Endocrinology 161, no. 2 (2009): 345–53. http://dx.doi.org/10.1530/eje-09-0130.

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ObjectiveIn vitro experiments and in vivo studies on rodents demonstrate that N-terminal 14, 15, 16, 17, and 18 kDa fragments prolactin-related vasoinhibin (PRL-V) of human PRL are natural inhibitors of neovascularization in the retina and elsewhere. These N-terminal PRL fragments belong to a family of peptides named vasoinhibins, which act as endogenous regulators of angiogenesis and vascular function. These observations led to the hypothesis that PRL-V could play a role in the pathophysiology of diabetic retinopathy in humans. The purpose of this study was to investigate whether patients wit

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Memon, Waseem Raja, Bharat Lal, and Abdul Aziz Sahto. "DIABETIC RETINOPATHY;." Professional Medical Journal 24, no. 02 (2017): 234–38. http://dx.doi.org/10.29309/tpmj/2017.24.02.510.

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Objectives: The purpose behind this study was to frequency of diabeticretinopathy at level of hba1c greater than 6.5%. Material and Methods: 130 patients with type-IIdiabetes mellitus with duration of more than >5years with HbA1c level of >6.5% were selected.After taking detailed history regarding diabetes mellitus and diabetic retinopathy, Fundoscopicexamination of eye was done. All the information was noted in proforma and analyzed usingSPSS version 16.0. Results: Frequency of diabetic retinopathy was observed in 23.85%(31/130) and in those cases average HBA1C was 8.08±0.91 (%). Regard

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Longa-López, John, Miguel Mavila-Salon, and Luis A. Rodriguez-Dominguez. "Prevalence and factors associated with retinopathy in patients of the integral diabetes program of the san genaro de villa Chorillos health center, Lima-Peru." Revista de la Facultad de Medicina Humana 22, no. 3 (2022): 522–32. http://dx.doi.org/10.25176/rfmh.v22i3.4951.

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Objectives: To determine the prevalence and factors associated with retinopathy in patients of the Comprehensive Diabetes Program of the San Genaro Health Center in Villa Chorrillos. Methods: Descriptive, observational, cross-sectional, prospective study; with a sample of 119 adults and older adults. Non-probabilistic convenience sampling was used. The variables studied were diabetic retinopathy, type of diabetic retinopathy, degree of diabetic retinopathy, age, sex, educational level, time of illness, time belonging to the program, type of treatment, personal history of arterial hypertension,

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Iyer, Deepthi Prabhakar, Rajashekar Dyaberi, and Yallappa Bhajantri. "Visual Outcomes Following Grid Photocoagulation in Non-Proliferative Diabetic Retinopathy with Diabetic Macular Edema: Correlation with Systemic Factors." SSR Institute of International Journal of Life Sciences 11, no. 2 (2025): 7050–58. https://doi.org/10.21276/ssr-iijls.2025.11.2.8.

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