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1

Olovyannikova, R. Ya, Т. A. Makarenko, E. V. Lychkovskaya, et al. "Chemical mechanisms of non-thermal plasma action on cells." Fundamental and Clinical Medicine 5, no. 4 (2020): 104–16. http://dx.doi.org/10.23946/2500-0764-2020-5-4-104-115.

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Non-thermal plasma (NTP) in the air around the cell layer or biological tissues is considered as a generator of reactive oxygen and nitrogen species, ions, and solvated/aquated electrons. This review covers current understanding on the effects of NTP in living systems, with the focus on the role of free radicals and other NTP-generated particles in the chemical modification of biomacromolecules and regulation of signal transduction. We summarise recent data on the impact of NTP-originated products on intracellular redox balance, mitochondrial biogenesis, cell membranes and organelles. In addit
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Veerana, Mayura, Nannan Yu, Wirinthip Ketya, and Gyungsoon Park. "Application of Non-Thermal Plasma to Fungal Resources." Journal of Fungi 8, no. 2 (2022): 102. http://dx.doi.org/10.3390/jof8020102.

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In addition to being key pathogens in plants, animals, and humans, fungi are also valuable resources in agriculture, food, medicine, industry, and the environment. The elimination of pathogenic fungi and the functional enhancement of beneficial fungi have been the major topics investigated by researchers. Non-thermal plasma (NTP) is a potential tool to inactivate pathogenic and food-spoiling fungi and functionally enhance beneficial fungi. In this review, we summarize and discuss research performed over the last decade on the use of NTP to treat both harmful and beneficial yeast- and filamento
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3

Tanaka, Hiromasa, Masaaki Mizuno, Kenji Ishikawa, et al. "Molecular mechanisms of non-thermal plasma-induced effects in cancer cells." Biological Chemistry 400, no. 1 (2018): 87–91. http://dx.doi.org/10.1515/hsz-2018-0199.

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AbstractPlasma is the fourth state of matter with higher energy than gas; non-thermal plasma (NTP) is currently available. As NTP is useful in sterilization, promoting wound healing and cancer treatments, the molecular mechanisms of plasma-induced effects in living cells and microorganisms are of significant interest in plasma medicine with medical-engineering collaboration. Molecular mechanisms of plasma-induced effects in cancer cells will be described in this minireview. Both direct and indirect methods to treat cancer cells with NTP have been developed. NTP interacts directly with not only
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Gholami, Rahman, Cristina E. Stere, Alexandre Goguet, and Christopher Hardacre. "Non-thermal-plasma-activated de-NO x catalysis." Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences 376, no. 2110 (2017): 20170054. http://dx.doi.org/10.1098/rsta.2017.0054.

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The combination of non-thermal plasma (NTP) with catalyst systems as an alternative technology to remove NO x emissions in the exhaust of lean-burn stationary and mobile sources is reviewed. Several factors, such as low exhaust gas temperatures (below 300°C), low selectivity to N 2 and the presence of impurities, make current thermally activated technologies inefficient. Various hybrid plasma–catalyst systems have been examined and shown to have a synergistic effect on de-NO x efficiency when compared with NTP or catalyst-alone systems. The NTP is believed to form oxygenated species, such as a
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Tuhvatulin, A. I., E. V. Sysolyatina, D. V. Scheblyakov, et al. "Non-Thermal Plasma Causes P53-Dependent Apoptosis in Human Colon Carcinoma Cells." Acta Naturae 4, no. 3 (2012): 82–87. http://dx.doi.org/10.32607/20758251-2012-4-3-82-87.

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Non-thermal plasma (NTP) consists of a huge amount of biologically active particles, whereas its temperature is close to ambient. This combination allows one to use NTP as a perspective tool for solving different biomedical tasks, including antitumor therapy. The treatment of tumor cells with NTP caused dose-dependent effects, such as growth arrest and apoptosis. However, while the outcome of NTP treatment has been established, the molecular mechanisms of the interaction between NTP and eukaryotic cells have not been thoroughly studied thus far. In this work, the mechanisms and the type of dea
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Holubová, Ľudmila, Stanislav Kyzek, Ivana Ďurovcová, et al. "Non-Thermal Plasma—A New Green Priming Agent for Plants?" International Journal of Molecular Sciences 21, no. 24 (2020): 9466. http://dx.doi.org/10.3390/ijms21249466.

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Since the earliest agricultural attempts, humankind has been trying to improve crop quality and yields, as well as protect them from adverse conditions. Strategies to meet these goals include breeding, the use of fertilisers, and the genetic manipulation of crops, but also an interesting phenomenon called priming or adaptive response. Priming is based on an application of mild stress to prime a plant for another, mostly stronger stress. There are many priming techniques, such as osmopriming, halopriming, or using physical agents. Non-thermal plasma (NTP) represents a physical agent that contai
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Le Bras, Florian, Gaëlle Carré, Yasmina Aguemon, Marius Colin, and Marie-Paule Gellé. "Inactivation of Enveloped Bovine Viral Diarrhea Virus and Non-Enveloped Porcine Parvovirus Using Low-Pressure Non-Thermal Plasma." Life 11, no. 12 (2021): 1292. http://dx.doi.org/10.3390/life11121292.

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As the worldwide population has been experiencing since 2020, viruses represent a serious threat to global well-being. To avoid viral transmission through surgery or medical examination, sterilization of medical material is needed. From emerging sterilization processes, the use of non-thermal plasma (NTP) arises as a promising technique to efficiently reduce microbial burden on medical devices, including new complex polymers as thermosensitive ones. Thus, we evaluated the antiviral efficacy of a low-pressure NTP process taking place in a sealed bag. For this purpose, two different plasmas, O2
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Moszczyńska, Julia, Katarzyna Roszek, and Marek Wiśniewski. "Non-Thermal Plasma Application in Medicine—Focus on Reactive Species Involvement." International Journal of Molecular Sciences 24, no. 16 (2023): 12667. http://dx.doi.org/10.3390/ijms241612667.

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Non-thermal plasma (NTP) application in medicine is a dynamically developing interdisciplinary field. Despite the fact that basics of the plasma phenomenon have been known since the 19th century, growing scientific attention has been paid in recent years to the use of plasma in medicine. Three most important plasma-based effects are pivotal for medical applications: (i) inactivation of a broad spectrum of microorganisms, (ii) stimulation of cell proliferation and angiogenesis with lower plasma treatment intensity, and (iii) inactivation of cells by initialization of cell death with higher plas
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9

Adnan, Zulfam, Sadullah Mir, and Mudassar Habib. "Exhaust gases depletion using non-thermal plasma (NTP)." Atmospheric Pollution Research 8, no. 2 (2017): 338–43. http://dx.doi.org/10.1016/j.apr.2016.10.005.

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10

Scholtz, Vladimír, Jana Jirešová, Božena Šerá, and Jaroslav Julák. "A Review of Microbial Decontamination of Cereals by Non-Thermal Plasma." Foods 10, no. 12 (2021): 2927. http://dx.doi.org/10.3390/foods10122927.

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Cereals, an important food for humans and animals, may carry microbial contamination undesirable to the consumer or to the next generation of plants. Currently, non-thermal plasma (NTP) is often considered a new and safe microbicidal agent without or with very low adverse side effects. NTP is a partially or fully ionized gas at room temperature, typically generated by various electric discharges and rich in reactive particles. This review summarizes the effects of NTP on various types of cereals and products. NTP has undisputed beneficial effects with high potential for future practical use in
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11

Lux, Jaroslav, Radim Dobiáš, Ivana Kuklová, et al. "Inactivation of Dermatophytes Causing Onychomycosis and Its Therapy Using Non-Thermal Plasma." Journal of Fungi 6, no. 4 (2020): 214. http://dx.doi.org/10.3390/jof6040214.

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Onychomycosis is one of the most common nail disorders. Its current treatment is not satisfactorily effective and often causes adverse side effects. This study aims to determine the optimal conditions for non-thermal plasma (NTP) inactivation of the most common dermatophytes in vitro and to apply it in patient`s therapy. The in vitro exposure to NTP produced by negative DC corona discharge caused full inactivation of Trichophyton spp. if applied during the early growth phases. This effect decreased to negligible inactivation with the exposure applied six days after inoculation. In a group of 4
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Vaiano, Vincenzo, and Giuseppina Iervolino. "Non-Thermal Plasma-Assisted Catalytic Reactions for Environmental Protection." Catalysts 11, no. 4 (2021): 509. http://dx.doi.org/10.3390/catal11040509.

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13

Cai, Yi Xi, Li Li Lei, and Pan Wang. "The Effect of Specific Input Energy on Promotion of NO–NO2 of Diesel Engine with Non-Thermal Plasma Technology." Advanced Materials Research 204-210 (February 2011): 955–59. http://dx.doi.org/10.4028/www.scientific.net/amr.204-210.955.

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The removal of diesel exhausts by non-thermal plasma technology has been investigated focused on the simulation gas experiment at atmospheric pressure and room temperature for many years. However, the research for real diesel engine is need to be further studied. In the experiments, a non-thermal plasma (NTP) reactor was designed based upon dielectric barrier discharge. NO/NO2 conversion was studied as a function of the specific input energy (SIE) by varying the frequency and voltage applied on the NTP reactor through bench test. Results showed that NTP SIE was increased with the voltage at ea
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Sysolyatina, E., A. Petryakov, M. Abdulkadieva, et al. "Use of non-thermal plasma for decontamination of titanium implants." Journal of Physics: Conference Series 2270, no. 1 (2022): 012045. http://dx.doi.org/10.1088/1742-6596/2270/1/012045.

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Abstract Non-thermal plasma (NTP) has a non-specific bactericidal effect as a result of the synergistic activity of biologically active components contained in the plasma torch. As part of this work, we investigated the potential of using NTP for the antibacterial treatment of titanium implants. Applying samples made of the VT6 titanium alloy used to create implants and a strain of antibiotic-resistant staphylococcus MRSA, we showed that 1) plasma pretreatment of the sample surface led to the formation of a film containing titanium oxides which have a weak bactericidal effect reducing the colo
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15

Lee, Sung-Tak, Yoon-Seo Jang, Uk-Kyu Kim, et al. "Non-thermal plasma application enhances the recovery of transected sciatic nerves in rats." Experimental Biology and Medicine 246, no. 11 (2021): 1287–96. http://dx.doi.org/10.1177/1535370221996655.

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This experimental research aimed to investigate the effects of non-thermal plasma on nerve regeneration after transected nerve damage using the sciatic nerve in Wistar albino (A) rats. The experiments were performed on 27 Wistar A rats. The rats underwent surgery for right sciatic nerve exposure and were divided into three groups (each group, n = 9) according to sciatic nerve transected injury (SNTI) and non-thermal plasma application: a non-nerve damage (non-ND) group, a only nerve damage without non-thermal plasma application (ND) group, and a nerve damage with non-thermal plasma application
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16

Sutter, Julia, Jascha Brettschneider, Sara Mamchur, Fred Krebs, Sophia Gershman, and Vandana Miller. "Inclusion of Biological Targets in the Analysis of Electrical Characteristics of Non-Thermal Plasma Discharge." Plasma 6, no. 3 (2023): 577–91. http://dx.doi.org/10.3390/plasma6030040.

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In Plasma Medicine studies, the effect of non-thermal plasma (NTP) on biological targets is typically correlated with the amount of stable reactive oxygen and nitrogen species produced in a liquid medium. The effect of NTP and the response of the biological target on cellular redox mechanisms is overlooked in these investigations. Additionally, the influence of electrical properties of cells on the physical properties of NTP is neglected. Therefore, we used a floating electrode dielectric barrier discharge plasma to explore the impact of cell structure, size, and viability of the biological ta
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Rodríguez-Méndez, Benjamín G., Régulo López-Callejas, Antonio Mercado-Cabrera, et al. "Harnessing Non-Thermal Plasma to Supercharge Recovery in Abdominal Surgeries: A Pilot Study." Journal of Clinical Medicine 13, no. 2 (2024): 408. http://dx.doi.org/10.3390/jcm13020408.

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(1) Background: This study aims to evaluate the efficacy and safety of non-thermal plasma (NTP) therapy in accelerating wound healing in patients who have undergone laparoscopic and open surgeries. (2) Methods: NTP was applied using a needle-type reactor with an irradiance of 0.5 W/cm2 on the surgical wounds of fifty patients after obtaining informed consent. Three NTP treatments, each lasting three minutes, were administered hourly. (3) Results: The pilot study showed that NTP-treated surgical wounds healed completely without any signs of infection, dehiscence, pain, or itching. Notably, pati
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18

Arisawa, Emilia Angela Lo Schiavo, Juliana Cunha Cardoso, Lucia Vieira, and Rauirys Alencarde de Oliveira. "Non-thermal plasma applied to treating diabetic foot." Research, Society and Development 10, no. 12 (2021): e539101220128. http://dx.doi.org/10.33448/rsd-v10i12.20128.

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Objective: Evaluate the effects of non-thermal plasma therapy (NTP) for the treatment of diabetic foot injuries in two patients, considering the evolution of the steps of the healing process, pain sensitivity, and quality of life. Methodology: Lesions in the lower limbs of two patients with Diabetes mellitus (DM) with similar anatomical location and dimensions were treated, one patient with controlled DM and the other classified as uncontrolled DM. The application of NTP was performed for 10 minutes, 3 times a week in direct contact with the lesions. The same protocol was applied in both clini
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Kim, Hee-Jun, Chan-Hee Won, and Hyun-Woo Kim. "Optimized Pretreatment of Non-Thermal Plasma for Advanced Sewage Oxidation." International Journal of Environmental Research and Public Health 17, no. 20 (2020): 7694. http://dx.doi.org/10.3390/ijerph17207694.

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This study investigates how the non-thermal plasma (NTP) process leads to advanced oxidation of sewage using response surface methodology. For environmentally viable and efficient operation of the NTP process, temperature and contact time were selected as two important independent variables. Their impacts on the performance were tested following an experimental design to figure out optimal operating conditions. Based on obtained treatment efficiency, statistically optimized conditions were derived by using an approach adapting the central composite design. Results show that coupling 40 °C of t
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20

Baniya, Hom Bahadur, Santosh Dhungana, Akhilash Kumar Singh, et al. "Effects on physiochemical parameters of water samples by non-thermal plasma treatment." Journal of Nepal Physical Society 10, no. 2 (2024): 19–29. https://doi.org/10.3126/jnphyssoc.v10i2.79472.

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Non-thermal plasma (NTP) is a rapidly advancing multidisciplinary field, gaining recognition for its environmentally friendly and chemical-free attributes. Over the past decade, NTP has drawn considerable interest due to its extensive potential applications, particularly in the realm of water treatment. When applied to water, NTP creates an acidic environment, which significantly modifies several key properties, including pH, electrical conductivity, and turbidity. Additionally, the process generates reactive oxygen and nitrogen species (RONS), which induce notable changes in the chemical comp
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Doshi, Pratik, and Božena Šerá. "Role of Non-Thermal Plasma in Fusarium Inactivation and Mycotoxin Decontamination." Plants 12, no. 3 (2023): 627. http://dx.doi.org/10.3390/plants12030627.

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Fusarium spp. is a well-studied pathogen with the potential to infect cereals and reduce the yield to maximum if left unchecked. For decades, different control treatments have been tested against different Fusarium spp. and for reducing the mycotoxins they produce and are well documented. Some treatments also involved integrated pest management (IPM) strategies against Fusarium spp. control and mycotoxin degradation produced by them. In this review article, we compiled different control strategies against different Fusarium spp. In addition, special focus is given to the non-thermal plasma (NT
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Baloul, Yasmine, Olivier Aubry, Hervé Rabat, Cyril Colas, Benoît Maunit, and Dunpin Hong. "Paracetamol degradation in aqueous solution by non-thermal plasma." European Physical Journal Applied Physics 79, no. 3 (2017): 30802. http://dx.doi.org/10.1051/epjap/2017160472.

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This study deals with paracetamol degradation in water using a non-thermal plasma (NTP) created by a dielectric barrier discharge (DBD). The effects of the NTP operating conditions on the degradation were studied, showing that the treatment efficiency of the process was highly dependent on the electrical parameters and working gas composition in the reactor containing the aqueous solution. A conversion rate higher than 99% was reached with an energy yield of 12 g/kWh. High resolution mass spectrometry (HRMS) measurements showed that the main species produced in water during the process were ni
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Tvrdá, Eva, Daniel Lovíšek, Stanislav Kyzek, Dušan Kováčik, and Eliška Gálová. "The Effect of Non-Thermal Plasma on the Structural and Functional Characteristics of Human Spermatozoa." International Journal of Molecular Sciences 22, no. 9 (2021): 4979. http://dx.doi.org/10.3390/ijms22094979.

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Significant antibacterial properties of non-thermal plasma (NTP) have converted this technology into a promising alternative to the widespread use of antibiotics in assisted reproduction. As substantial data available on the specific in vitro effects of NTP on male reproductive cells are currently missing, this study was designed to investigate selected quality parameters of human spermatozoa (n = 51) exposed to diffuse coplanar surface barrier discharge NTP for 0 s, 15 s, 30 s, 60 s and 90 s. Sperm motility characteristics, membrane integrity, mitochondrial activity, production of reactive ox
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Lin, Abraham, Jamoliddin Razzokov, Hanne Verswyvel, et al. "Oxidation of Innate Immune Checkpoint CD47 on Cancer Cells with Non-Thermal Plasma." Cancers 13, no. 3 (2021): 579. http://dx.doi.org/10.3390/cancers13030579.

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Non-thermal plasma (NTP) therapy has been emerging as a promising cancer treatment strategy, and recently, its ability to locally induce immunogenic cancer cell death is being unraveled. We hypothesized that the chemical species produced by NTP reduce immunosuppressive surface proteins and checkpoints that are overexpressed on cancerous cells. Here, 3D in vitro tumor models, an in vivo mouse model, and molecular dynamics simulations are used to investigate the effect of NTP on CD47, a key innate immune checkpoint. CD47 is immediately modulated after NTP treatment and simulations reveal the pot
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Lee, Seon-Ki, Min-Kyung Ji, Yu-Jin Jo, Chan Park, Hoonsung Cho, and Hyun-Pil Lim. "Effect of Non-Thermal Plasma Treatment of Contaminated Zirconia Surface on Porphyromonas gingivalis Adhesion and Osteoblast Viability." Materials 15, no. 15 (2022): 5348. http://dx.doi.org/10.3390/ma15155348.

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Plasma treatment on a zirconia surface prevents bacterial contamination and maintains osteoblast activity. To assess the degree of adhesion of Porphyromonas gingivalis on a zirconia surface after non-thermal plasma (NTP) treatment, specimens were treated with plasma for 60, 300, and 600 s, after which P. gingivalis was inoculated onto the surface and incubated for 48 h. To assess osteoblast activity after NTP treatment, osteoblasts (MC3T3-E1) were dispensed onto the specimens contaminated with P. gingivalis immediately after NTP for 60 and 120 s, followed by incubation for 48, 72, and 96 h. P.
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Choi, Hee-Young, Hyun-Joo Kim, Ju-Youn Lee, and Ji-Young Joo. "Adjunctive Treatment Effect of Non-Thermal Atmospheric Pressure Plasma in Periodontitis-Induced Rats." Journal of Clinical Medicine 14, no. 3 (2025): 896. https://doi.org/10.3390/jcm14030896.

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Background/Objectives: As non-thermal atmospheric pressure plasma (NTP) is known to have advantages in application in the medical field, we consider its applicability to periodontitis, a representative chronic inflammatory disease. The purpose of this study was to evaluate the effect of NTP in inhibiting the progression of periodontitis in a rat model when additionally used in scaling and root planing (SRP). Methods: To induce experimental periodontitis in 20 rats, ligatures were placed in the maxillary second molar and lipopolysaccharide from Porphyromonas gingivalis was injected around the t
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Khun, Josef, Anna Machková, Petra Kašparová, et al. "Non-Thermal Plasma Sources Based on Cometary and Point-to-Ring Discharges." Molecules 27, no. 1 (2021): 238. http://dx.doi.org/10.3390/molecules27010238.

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A non-thermal plasma (NTP) is a promising tool against the development of bacterial, viral, and fungal diseases. The recently revealed development of microbial resistance to traditional drugs has increased interest in the use of NTPs. We have studied and compared the physical and microbicidal properties of two types of NTP sources based on a cometary discharge in the point-to-point electrode configuration and a corona discharge in the point-to-ring electrode configuration. The electrical and emission properties of both discharges are reported. The microbicidal effect of NTP sources was tested
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Lafontaine, Julie, Jean-Sébastien Boisvert, Audrey Glory, Sylvain Coulombe, and Philip Wong. "Synergy between Non-Thermal Plasma with Radiation Therapy and Olaparib in a Panel of Breast Cancer Cell Lines." Cancers 12, no. 2 (2020): 348. http://dx.doi.org/10.3390/cancers12020348.

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Cancer therapy has evolved to a more targeted approach and often involves drug combinations to achieve better response rates. Non-thermal plasma (NTP), a technology rapidly expanding its application in the medical field, is a near room temperature ionized gas capable of producing reactive species, and can induce cancer cell death both in vitro and in vivo. Here, we used proliferation assay to characterize the plasma sensitivity of fourteen breast cancer cell lines. These assays showed that all tested cell lines were sensitive to NTP. In addition, a good correlation was found comparing cell sen
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Russo, Mariaconcetta, Giuseppina Iervolino, Vincenzo Vaiano, and Vincenzo Palma. "Non-Thermal Plasma Coupled with Catalyst for the Degradation of Water Pollutants: A Review." Catalysts 10, no. 12 (2020): 1438. http://dx.doi.org/10.3390/catal10121438.

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Non-thermal plasma is one of the most promising technologies used for the degradation of hazardous pollutants in wastewater. Recent studies evidenced that various operating parameters influence the yield of the Non-Thermal Plasma (NTP)-based processes. In particular, the presence of a catalyst, suitably placed in the NTP reactor, induces a significant increase in process performance with respect to NTP alone. For this purpose, several researchers have studied the ability of NTP coupled to catalysts for the removal of different kind of pollutants in aqueous solution. It is clear that it is stil
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Lokajová, Eliška, Jaroslav Julák, Josef Khun, et al. "Inactivation of Dermatophytes Causing Onychomycosis Using Non-Thermal Plasma as a Prerequisite for Therapy." Journal of Fungi 7, no. 9 (2021): 715. http://dx.doi.org/10.3390/jof7090715.

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Following our previous study of the therapy of onychomycosis by non-thermal plasma (NTP) and nail hygiene and to obtain some prerequisite data of dermatophytes sensitivity, the dynamics of those inactivation by NTP plasma was monitored for various strains of Trichophyton iterdigitale, Trichophyton benhamiae, Trichophyton rubrum, and Microsporum canis. Three strains of each species on agar plates were exposed with plasma produced by a DC corona discharge in the point-to-ring arrangement in various time intervals. Although all strains were sufficiently sensitive to plasma action, significant dif
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Andersen, K. B., A. Feilberg, and J. A. Beukes. "Use of non-thermal plasma and UV-light for removal of odour from sludge treatment." Water Science and Technology 66, no. 8 (2012): 1656–62. http://dx.doi.org/10.2166/wst.2012.367.

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Non-thermal plasma (NTP) systems can be used for abatement of odour nuisances. Odour reductions are achieved by radical-initiated oxidation and dust collection in the plasma reactor. For some emissions a sequence of NTP followed by UV-light can improve the odour reduction further. This study was conducted to evaluate the efficiency of NTP technology combined with UV-light towards odour emissions from sludge treatment. Air from a pilot sludge dryer was treated with a pilot NTP and a UV unit. The effect of using an acid scrubber upstream the NTP system was also tested. Thermal desorption gas chr
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Kim, Han-Jun, Eun-Wook Choi, Eun-Ji Choi, et al. "Non-thermal plasma promotes hair growth by improving the inter-follicular macroenvironment." RSC Advances 11, no. 45 (2021): 27880–96. http://dx.doi.org/10.1039/d1ra04625j.

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Maillet, Christina, Florence M. Klein, Florian Le Bras, et al. "Cytocompatibility of titanium and poly(etheretherketone) surfaces after O2 non-thermal plasma sterilization." PLOS ONE 18, no. 8 (2023): e0290820. http://dx.doi.org/10.1371/journal.pone.0290820.

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The sterilization of medical devices is paramount to achieve an acceptable level of sterility assurance and to prevent hospital-acquired infections. However, some medical devices cannot be sterilized by usual processes such as autoclave (AC) and gamma-ray irradiation (GI). A new non-thermal plasma (NTP) process using sealed bag that preserves the sterile state of the devices could be used as an alternative sterilization method. The aim of the study was to assess the cytocompatibility of titanium and poly(etheretherketone) (PEEK) surfaces after O2-NTP sterilization compared to GI and AC. MG-63
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Mildaziene, Vida, Anatolii Ivankov, Bozena Sera, and Danas Baniulis. "Biochemical and Physiological Plant Processes Affected by Seed Treatment with Non-Thermal Plasma." Plants 11, no. 7 (2022): 856. http://dx.doi.org/10.3390/plants11070856.

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Among the innovative technologies being elaborated for sustainable agriculture, one of the most rapidly developing fields relies on the positive effects of non-thermal plasma (NTP) treatment on the agronomic performance of plants. A large number of recent publications have indicated that NTP effects are far more persistent and complex than it was supposed before. Knowledge of the molecular basis and the resulting outcomes of seed treatment with NTP is rapidly accumulating and requires to be analyzed and presented in a systematic way. This review focuses on the biochemical and physiological pro
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Mohamed, Hager, Eric Gebski, Rufranshell Reyes, et al. "Differential Effect of Non-Thermal Plasma RONS on Two Human Leukemic Cell Populations." Cancers 13, no. 10 (2021): 2437. http://dx.doi.org/10.3390/cancers13102437.

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Non-thermal plasma application to cancer cells is known to induce oxidative stress, cytotoxicity and indirect immunostimulatory effects on antigen presenting cells (APCs). The purpose of this study was to evaluate the responses of two leukemic cell lines—Jurkat T lymphocytes and THP-1 monocytes—to NTP-generated reactive oxygen and nitrogen species (RONS). Both cell types depleted hydrogen peroxide, but THP-1 cells neutralized it almost immediately. Jurkat cells transiently blunted the frequency-dependent increase in nitrite concentrations in contrast to THP-1 cells, which exhibited no immediat
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Mohan, Harshini, Subash Mohandoss, Natarajan Balasubramaniyan, and Sivachandiran Loganathan. "Non-Thermal Plasma-Assisted Synthesis of ZnO for Enhanced Photocatalytic Performance." Plasma 8, no. 2 (2025): 25. https://doi.org/10.3390/plasma8020025.

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Non-thermal plasma (NTP)-assisted material synthesis and surface modification provide a promising approach in various applications, particularly in wastewater treatment. In this study, we reported the synthesis of photocatalytic zinc oxide (ZnO) from zinc hydroxide (Zn(OH)2) utilizing NTP discharge generated by dielectric barrier discharge (DBD). The results demonstrated that the 40 min plasma treatment at 200 °C (ZnO-P) with a voltage of 20 kV significantly improved the material’s physicochemical properties compared to conventional calcination at 600 °C (ZnO-600). ZnO-P exhibited better cryst
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Arguello-Sánchez, Raúl, Régulo López-Callejas, Benjamín Gonzalo Rodríguez-Méndez, et al. "Innovative Curved-Tip Reactor for Non-Thermal Plasma and Plasma-Treated Water Generation: Synergistic Impact Comparison with Sodium Hypochlorite in Dental Root Canal Disinfection." Materials 16, no. 22 (2023): 7204. http://dx.doi.org/10.3390/ma16227204.

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Non-thermal plasmas (NTPs), known as cold atmospheric plasmas (CAPs), hold great potential for diverse medical applications, including dentistry. However, traditional linear and rigid dielectric barrier discharge reactors used for NTP generation encounter limitations in accessing oral cavities and root canals. To address this issue, we have developed an innovative NTP reactor featuring an angled end for improved accessibility. The central copper electrode, with a 0.59 mm diameter and adjustable length for desired angulation, is coated with zircon powder (ZrSiO4) to ensure stable NTP generation
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Smolková, Barbora, Adam Frtús, Mariia Uzhytchak, et al. "Critical Analysis of Non-Thermal Plasma-Driven Modulation of Immune Cells from Clinical Perspective." International Journal of Molecular Sciences 21, no. 17 (2020): 6226. http://dx.doi.org/10.3390/ijms21176226.

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The emerged field of non-thermal plasma (NTP) shows great potential in the alteration of cell redox status, which can be utilized as a promising therapeutic implication. In recent years, the NTP field considerably progresses in the modulation of immune cell function leading to promising in vivo results. In fact, understanding the underlying cellular mechanisms triggered by NTP remains incomplete. In order to boost the field closer to real-life clinical applications, there is a need for a critical overview of the current state-of-the-art. In this review, we conduct a critical analysis of the NT
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Wang, Zongyu, Hailang Kuang, Jifeng Zhang, Lilin Chu, and Yulong Ji. "Nitrogen oxide removal by non-thermal plasma for marine diesel engines." RSC Advances 9, no. 10 (2019): 5402–16. http://dx.doi.org/10.1039/c8ra09217f.

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Kumar Das, Smrutiprava, and Rajesh Kumar Mahanta. "­­­­­­Exploring surface diversification of polyvinyl alcohol/polyethylene glycol Composites by cold plasma: Ompact of Argon and oxygen plasmas on biomedical application." International Journal of Pharmaceutical Chemistry and Analysis 11, no. 4 (2024): 331–40. https://doi.org/10.18231/j.ijpca.2024.048.

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Tetraethyl orthosilicate was used as a crosslinker to create composites made of polyvinyl alcohol and polyethylene glycol (PVA/PEG (PP)). The composites were exposed to non-thermal plasma (NTP) treatment with an Argon and oxygen gas mixture. The NTP treatment resulted in an improvement in surface hydrophilicity. Physiographical investigations indicated surface nanotexturing, but bulk properties were unaffected. After twenty days of exposure to air, there was no detectable ageing effect, showing that the NTP-modified composites were extremely robust. The composites swelled more in intestinal pH
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Katiyar, Kritika S., Abraham Lin, Alexander Fridman, Carolyn E. Keating, D. Kacy Cullen, and Vandana Miller. "Non-Thermal Plasma Accelerates Astrocyte Regrowth and Neurite Regeneration Following Physical Trauma In Vitro." Applied Sciences 9, no. 18 (2019): 3747. http://dx.doi.org/10.3390/app9183747.

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Non-thermal plasma (NTP), defined as a partially ionized gas, is an emerging technology with several biomedical applications, including tissue regeneration. In particular, NTP treatment has been shown to activate endogenous biological processes to promote cell regrowth, differentiation, and proliferation in multiple cell types. However, the effects of this therapy on nervous system regeneration have not yet been established. Accordingly, the current study explored the effects of a nanosecond-pulsed dielectric barrier discharge plasma on neural regeneration. Following mechanical trauma in vitro
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Gutiérrez-León, Diana Guadalupe, Tomás Serrano-Ramírez, Régulo López-Callejas, and Benjamín Gonzalo Rodríguez-Méndez. "Non-Thermal Plasma as an Alternative to Enhance the Early Growth Structures in Lentil Plants." Agronomy 12, no. 12 (2022): 2920. http://dx.doi.org/10.3390/agronomy12122920.

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The scarcity and contamination of water, aggravated by the effects of Climate Change, endanger the food supply, cause health problems to humans, and are a critical concern. New research has been carried out to improve the quality of water used in the agricultural sector. One of them is the technology of non-thermal plasma (NTP) generated by corona discharges using air as a working gas. In this study, the NTP is applied directly and causing the activation to three water sources: potable, wastewater from poultry farming, and rain, on the legume “lentil.” The results show that the NTP applied to
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Ibáñez-Mancera, Norma Guadalupe, Régulo López-Callejas, Víctor Hugo Toral-Rizo, et al. "Healing of Recurrent Aphthous Stomatitis by Non-Thermal Plasma: Pilot Study." Biomedicines 11, no. 1 (2023): 167. http://dx.doi.org/10.3390/biomedicines11010167.

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Recurrent aphthous stomatitis (RAS) is a common disease in the oral cavity characterized by recurrent ulcers (RU). Usually, these cause acute pain without definitive treatment. The present study determines the efficacy of non-thermal plasma (NTP) for treating RU. NTP is applied to the patient’s RU using a radiofrequency generator connected to a point reactor. The power density applied to the ulcer is 0.50 W/cm2, less than 4 W/cm2, which is the maximum value without biological risk. Each patient received two treatments of three minutes each and spaced 60 min apart at a distance of 5 mm from the
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Yang, Yuhan, Yuan Wang, Shang Wei, Xianzhong Wang, and Jiaojiao Zhang. "Effects and Mechanisms of Non-Thermal Plasma-Mediated ROS and Its Applications in Animal Husbandry and Biomedicine." International Journal of Molecular Sciences 24, no. 21 (2023): 15889. http://dx.doi.org/10.3390/ijms242115889.

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Non-thermal plasma (NTP) is an ionized gas composed of neutral and charged reactive species, electric fields, and ultraviolet radiation. NTP presents a relatively low discharge temperature because it is characterized by the fact that the temperature values of ions and neutral particles are much lower than that of electrons. Reactive species (atoms, radicals, ions, electrons) are produced in NTP and delivered to biological objects induce a set of biochemical processes in cells or tissues. NTP can mediate reactive oxygen species (ROS) levels in an intensity- and time-dependent manner. ROS homeos
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Hsueh, Ming-Hsien, Chia-Nan Wang, Meng-Chang Hsieh, et al. "An Analysis of Exhaust Emission of the Internal Combustion Engine Treated by the Non-Thermal Plasma." Molecules 25, no. 24 (2020): 6041. http://dx.doi.org/10.3390/molecules25246041.

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Industries’ air pollution causes serious challenges to modern society, among them exhaust gases from internal combustion engines, which are currently one of the main sources. This study proposes a non-thermal plasma (NTP) system for placement in the exhaust system of internal combustion engines to reduce the toxic contaminants (HC, CO, and NOx) of exhaust gases. This NTP system generates a high-voltage discharge that not only responds to the ion chemical reaction to eliminate NOx and CO, but that also generates a combustion reaction at the local high temperature of plasma to reduce HC. The NTP
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Kim, Joo-Hak, Seonhee Kim, Shuyu Piao та ін. "Non-Thermal Plasma Attenuates TNF-α-Induced Endothelial Inflammation via ROS Modulation and NF-κB Inhibition". International Journal of Molecular Sciences 26, № 9 (2025): 4449. https://doi.org/10.3390/ijms26094449.

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Non-thermal plasma (NTP) has emerged as a promising therapeutic tool due to its anti-inflammatory properties; however, its molecular effects on vascular endothelial inflammation remain unclear. This study investigated the effects of NTP on tumor necrosis factor-alpha (TNF-α)-induced inflammation in human umbilical vein endothelial cells (HUVECs). NTP treatment significantly reduced intracellular reactive oxygen species (ROS) levels and downregulated the expression of adhesion molecules such as intercellular adhesion molecule-1 (ICAM-1) and vascular cell adhesion molecule-1 (VCAM-1), which are
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Srija, Mukherjee. "Application of dielectric dicharge based non-thermal plasma tool for treatment of wastewater." Journal of Indian Chemical Society Vol. 97, Apr 2020 (2020): 595–600. https://doi.org/10.5281/zenodo.5642745.

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Hooghly Institute of Technology, Vivekananda Rd, Chinsurah-712 103, West Bengal, India <em>E-mail</em>: sm49@iitbbs.ac.in <em>Manuscript received online 20 December 2019, accepted 20 March 2020</em> Recently the pharmaceutical compounds also called as &quot;emerging pollutants&quot; are becoming a vital class of pollutants due to their non-biodegradable nature. They are introduced into the food chain through aquatic life and suffer biomagnification thereafter, as a result of which they are of important concern. The methods conventionally applied hitherto for the treatment of water fail when ap
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Ahn, Jong-Ju, Dae-Sung Kim, Eun-Bin Bae, et al. "Effect of Non-Thermal Atmospheric Pressure Plasma (NTP) and Zirconia Primer Treatment on Shear Bond Strength between Y-TZP and Resin Cement." Materials 13, no. 18 (2020): 3934. http://dx.doi.org/10.3390/ma13183934.

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The purpose of this study was to investigate the effect of non-thermal atmospheric pressure plasma (NTP) treatment on the sandblasting of mechanical method and zirconia primer of chemical method used to increase the bond strength between zirconia and resin cement. In this study, Y-TZP was divided into 4 groups according to the surface treatment methods as follows: Zirconia primer (Pr), NTP + Zirconia primer (NTP + Pr), Sandblasting + Zirconia primer (Sb + Pr), Sandblasting + NTP + Zirconia primer (Sb + NTP + Pr). Then, two types of resin cement (G-CEM LinkAce and Rely X-U200) were used to meas
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Kulišová, Markéta, Michaela Rabochová, Jan Lorinčík, et al. "Comparative assessment of UV-C radiation and non-thermal plasma for inactivation of foodborne fungal spores suspension in vitro." RSC Advances 14, no. 24 (2024): 16835–45. http://dx.doi.org/10.1039/d4ra01689k.

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The comparative efficacy of UV radiation and non-thermal plasma (NTP) on key foodborn fungal contaminants was studied. UV-C radiation (254 nm) did not significantly suppress the metabolic activity of cells are spore germination whereas NTP exhibited almost 100% effectiveness.
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Shi, Yun Xi, Yi Xi Cai, Kang Hua Li, Xiao Hua Li, and Ya Yun Chen. "Experimental Study on the DPF Regeneration Based on Non-Thermal Plasma Technology." Applied Mechanics and Materials 325-326 (June 2013): 1347–51. http://dx.doi.org/10.4028/www.scientific.net/amm.325-326.1347.

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Diesel particulate filter (DPF) are considered to be the most effective means to reduce particulate emissions, and the key of DPF lies in their regeneration. O3 and O which have strong oxidability can be produced by non-thermal plasma (NTP) reactor. PM can be decomposed by these active substances to generate CO and CO2. The results show that PM deposited in the DPF can be removed by NTP technology without any catalyst and DPF can be completely regenerated at a lower temperature.
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