Academic literature on the topic 'Non-tuberculous Mycobacterium (NTM)'

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Journal articles on the topic "Non-tuberculous Mycobacterium (NTM)"

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Lyu, Jiwon. "Immunopathogenesis of Non-Tuberculous Mycobacteria Lung Disease." Korean Journal of Medicine 99, no. 4 (2024): 169–79. http://dx.doi.org/10.3904/kjm.2024.99.4.169.

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In recent years, the incidence and prevalence of non-tuberculous mycobacteria lung disease (NTM-LD) has been increasing worldwide. In Korea, <i>Mycobacterium avium</i> complex (MAC) and <i>Mycobacterium abscessus</i> complex account for most common cause of NTM-LD. It is essential to elucidate the pathophysiology of NTM-LD. The pathophysiology of NTM-LD has not been fully understood, however, it can be divided into bacterial and host-side factor. Among the host factor, innate immunity plays an essential role in the initial host immune response against intracellular non-
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Slathia, Pallavi, Deepti Narang, and Mudit Chandra. "Molecular Identification of Non-tuberculous Mycobacterial Species in Fecal samples from Cattle and Buffaloes." Indian Journal of Veterinary Sciences & Biotechnology 18, no. 5 (2022): 84–88. http://dx.doi.org/10.48165/ijvsbt.18.5.17.

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Abstract: The non-tuberculous mycobacteria (NTM) are ‘atypical mycobacteria’ belonging to species other than those classified in the Mycobacterium tuberculosis complex. NTM species have been reported to cause cross-reactive immune responses that interfere with the diagnosis of tuberculosis in both livestock and wildlife and are considered as potential pathogens for animals and humans. The present study was conducted for detection of non- tuberculous mycobacterial species (NTM) in fecal samples with a history of intermittent diarrhea from cattle and buffaloes. Polymerase Chain Reaction and PRA
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Wamalwa, Ronald, Bernard Guyah, and Nathan Shaviya. "Antibiotic Resistance in Mycobacterium Tuberculosis and Non-Tuberculous Mycobacteria." African Journal of Empirical Research 5, no. 4 (2024): 1001–10. http://dx.doi.org/10.51867/ajernet.5.4.83.

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Mycobacterium tuberculosis (MTB) and non-tuberculous mycobacteria (NTM) antibiotic resistance presents an important challenge to the treatment of mycobacterial infections. The therapeutic approaches are complicated by the resistance of both MTB and NTM to a variety of antibiotics. Resistance to first-line drugs such as isoniazid, rifampicin, ethambutol, and streptomycin has been consistently increasing in MTB, underscoring the necessity of effective treatment strategies. Conversely, the necessity of species-specific treatment regimens is underscored by the high resistance rates of NTM species,
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Opperman, Christoffel Johannes, and Adrian J. Brink. "Phage Therapy for Mycobacteria: Overcoming Challenges, Unleashing Potential." Infectious Disease Reports 17, no. 2 (2025): 24. https://doi.org/10.3390/idr17020024.

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Bacteriophage (phage) therapy is emerging as a promising alternative to traditional antibiotics for treating drug-resistant mycobacterial infections, including Mycobacterium tuberculosis complex (MTBC) and non-tuberculous mycobacteria (NTM) [...]
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Pan, Xinling, Yangxiao Zhou, Zhaoxia Li, et al. "Investigation of non-tuberculous mycobacteria in a primary hospital from southeastern China." Journal of Infection in Developing Countries 13, no. 12 (2019): 1095–100. http://dx.doi.org/10.3855/jidc.11772.

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Introduction: Non-tuberculous mycobacterium (NTM) can colonize the human body, leading to opportunistic infection. This study was conducted to analyze the NTM species composition in a primary hospital and investigate the potential features of the patients with different NTM species.
 Methodology: Mycobacterial strains were collected from the patients admitted at the hospital from January 2016 to May 2019. MPB64 assay was used to screen NTM strains and confirmed by Rv0577 amplification. The species were identified by hsp65 sequencing. The clinical records of patients with NTM were retrospe
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Molina-Torres, Carmen, Carlos Pedraza-Rodríguez, Lucio Vera-Cabrera, Jorge Ocampo-Candiani, Catalina Rivas-Morales, and Ezequiel Viveros-Valdez. "Antimycobacterial Activity of Hedeoma drummondii against Mycobacterium tuberculosis and Non-Tuberculous Mycobacteria." Antibiotics 12, no. 5 (2023): 833. http://dx.doi.org/10.3390/antibiotics12050833.

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Tuberculosis (TB) remains a major health problem worldwide, and the emergence of multi-resistant strains to first-line drugs has become the biggest obstacle to its treatment. On the other hand, the incidence of non-tuberculous mycobacteria (NTM) in humans has increased remarkably in recent years. The search for new and better treatments against mycobacterial infections is a constant at the global level. Hence, in this study, we propose to investigate the antimycobacterial effect of the extracts and major compounds of Hedeoma drummondii against clinical isolates of Mycobacterium tuberculosis an
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Kaur, Parvinder, Ramya Vadageri Krishnamurthy, Radha Krishan Shandil, Rahul Mohan, and Shridhar Narayanan. "A Novel Inhibitor against the Biofilms of Non-Tuberculous Mycobacteria." Pathogens 13, no. 1 (2023): 40. http://dx.doi.org/10.3390/pathogens13010040.

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Non-tuberculous Mycobacteria (NTM), previously classified as environmental microbes, have emerged as opportunistic pathogens causing pulmonary infections in immunocompromised hosts. The formation of the biofilm empowers NTM pathogens to escape from the immune response and antibiotic action, leading to treatment failures. NF1001 is a novel thiopeptide antibiotic first-in-class compound with potent activity against planktonic/replicating and biofilm forms of various NTM species. It is potent against both drug-sensitive and -resistant NTM. It has demonstrated a concentration-dependent killing of
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Manguba, Alexander S., Jaime Alfonso M. Aherrera, Antonio L. Faltado, Melissa A. Llanto, and Raul D. Jara. "Cardiac Tamponade Complicating Disseminated Non-tuberculous Mycobacterial Infection Involving the Pericardium: A Case Report." Philippine Journal of Cardiology 41, no. 1 (2013): 7–10. http://dx.doi.org/10.69944/pjc.598ed10d2d.

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BACKGROUND: The most common mycobacterial species causing infection in the Philippines is Mycobacterium tuberculosis. Non-tuberculous mycobacteria (NTM) have not been reported in Philippine literature to disseminate to the pericardium. CASE: We present a case of disseminated mycobacterial (tuberculous and non-tuberculous co-infection) involving the pericardium, pleura, spleen and abdominal wall. This is the case of a 37-year old female who presented with dyspnea and multiple nodules within the abdominal wall. Computed tomography scan showed a thickened pericardium with minimal pericardial effu
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Singh, Yogita, Raji Vasanth, Shrikala Baliga, and Dhanashree B. "UTILITY OF ANTIGEN DETECTION TEST AND POLYMERASE CHAIN REACTION IN THE DIFFERENTIATION OF TUBERCULOUS AND NON-TUBERCULOUS MYCOBACTERIA." Asian Journal of Pharmaceutical and Clinical Research 10, no. 6 (2017): 289. http://dx.doi.org/10.22159/ajpcr.2017.v10i6.18261.

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Objectives: Cultivation and identification of mycobacteria to species level remains difficult and time-consuming. Hence, easy and rapid diagnostic methods are necessary for the differentiation of Mycobacterium tuberculosis (MTB) from non-tuberculous mycobacteria (NTM). The present study aims to detect and differentiate MTB from NTM isolated from clinical samples by immunochromatographic test (ICT) and polymerase chain reaction (PCR). Methods: Over a period of 1 year, clinical samples (n=496) received from suspected cases of TB, at the Department of Microbiology, Kasturba Medical College Hospit
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Ojo, O. T., and A. O. Odeyemi. "Non-Mycobacteria Tuberculosis in Africa: A Literature Review." Ethiopian Journal of Health Sciences 33, no. 5 (2023): 913–18. http://dx.doi.org/10.4314/ejhs.v33i5.21.

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Background: Non-tuberculous mycobacteria (NTM) have been reported to cause pulmonary and extrapulmonary infections. These NTMs are often misdiagnosed as MTB due to their similar clinical presentations to tuberculosis, leading to inappropriate treatment and increased morbidity and mortality rates. This literature review aims to provide an overview of the prevalence, clinical manifestations, diagnosis, and management of NTM infections in Africa.
 Methods: A systematic search was performed using various electronic databases including PubMed, Scopus, and Web of Science. The search was limited
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Dissertations / Theses on the topic "Non-tuberculous Mycobacterium (NTM)"

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Gcebe, Nomakorinte. "The occurrence and molecular characterization of non-tuberculous mycobacteria in cattle, African buffalo (Syncerus caffer) and their environments in South Africa and genomic characterization and proteomic comparison with Mycobacterium bovis." Thesis, University of Pretoria, 2015. http://hdl.handle.net/2263/58682.

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The aim of this study was to investigate the diversity and prevalence of non-tuberculous mycobacteria (NTM) in cattle, African buffaloes and their environments in South Africa and the potential of these NTM to elicit cross- reactive immune responses in these animal species which may in turn lead to false diagnosis of bovine tuberculosis. A total of 40 NTM species were identified during a countrywide survey. Mycobacterium terrae, Mycobacterium nonchromogenicum, Mycobacterium vaccae/ Mycobacterium vanbaalenii and a group of isolates closely related to Mycobacterium moriokaense (M. moriokaense-li
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Robinson, Schuyler Thomas. "Geological and Geochemical Controls on Non-Tuberculous Mycobacterium Transmission: Examples from Hawaii." BYU ScholarsArchive, 2019. https://scholarsarchive.byu.edu/etd/8558.

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The opportunistic environmental microbes, non-tuberculous Mycobacterium (NTM), pose an increasing risk of disease and death in both immunodeficient and immunocompetent individuals in the USA and across the world. NTM lung disease is particularly prevalent in Hawaii, although the modes of NTM acquisition and transport in Hawaii are not fully understood. This study evaluated 149 soil and 50 water samples across the Hawaiian Islands to determine geochemical factors controlling NTM. Non-metric multidimensional scaling (NMDS) and principal component analyses (PCA) of modern soils show variables suc
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Berggren, Rebecca. "Jämförande studie av PCR-metoder för identifiering av icke-tuberkulösa mykobakterier." Thesis, Malmö universitet, Fakulteten för hälsa och samhälle (HS), 2020. http://urn.kb.se/resolve?urn=urn:nbn:se:mau:diva-26114.

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Den mest välkända arten i släktet Mycobacterium som kan orsaka sjukdom hos människan är Mycobacterium tuberculosis (MTB). Infektioner av andra mykobakterier ökar världen över. Dessa benämns icke-tuberkulösa mykobakterier (NTM) och orsakar ofta liknande symtom som de vid MTB-infektion. Vanligtvis krävs dock olika behandlingar beroende på om infektionen är orsakad av MTB eller av NTM. Nuvarande diagnostik bygger på odling och mikroskopi, men analyser som innefattar molekylärbiologiska metoder för undersökning av mykobakteriers DNA blir allt vanligare. I denna studie jämfördes olika PCR-metoder f
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Rodrigues, Renato Leitão. "Mycobacterium avium subsp. paratuberculosis: características e infeção." Master's thesis, 2019. http://hdl.handle.net/10284/8702.

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A mycobacterium avium subsp. paratuberculosis (MAP), é uma subespécie do complexo M. avium, que provoca a doença de Johne, uma enterite crónica em ruminantes e suspeita-se estar envolvida no desenvolvimento doença inflamatória intestinal crónica em humanos particularmente, na doença de Crohn. Devido a complexidade desta micobactéria é, importante o desenvolvimento de novas técnicas poderosas para a sua deteção e identificação, de maneira a obterem-se respostas mais concretas na associação desta subespécie de micobactéria a doença de Crohn. Neste trabalho através de uma revisão bibliográfica, d
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Book chapters on the topic "Non-tuberculous Mycobacterium (NTM)"

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Martínez-Jiménez, Santiago. "Nontuberculous Mycobacterial Infection." In Chest Imaging. Oxford University Press, 2019. http://dx.doi.org/10.1093/med/9780199858064.003.0039.

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Non-tuberculous mycobacteria (NTM), other than Mycobacterium tuberculosis (TB) may produce pulmonary infection. NTMI is typically an indolent infection except in immunocompromised and HIV infected patients. Imaging plays a crucial role in suggesting NTMI as a possible diagnosis in this patient population. Always consider classic or cavitary NTMI in patients with upper lobe cavitary disease similar to active cavitary TB. However, in such cases TB must always be excluded. In elderly white women, persistent right middle lobe/lingular atelectasis, bronchiectasis or consolidation should suggest the
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Liao, Yi-Wen, Yu-Rong Qin, and Liang Wang. "Comparative Genomics of Mycobacterium Species in Humans: Insights into Molecular Epidemiology, Virulence, and Antibiotic Resistance." In Mycobacteria - Comparative Genomics, Biomarker Identification, Laboratory Diagnosis and Clinical Treatment [Working Title]. IntechOpen, 2025. https://doi.org/10.5772/intechopen.1009402.

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Drug-resistant tuberculosis (TB) and non-tuberculous mycobacteria (NTM) infections pose significant global health challenges. Understanding the genomic diversity, pathogenicity, and mechanisms of antibiotic resistance in Mycobacterium species is critical for developing effective diagnostic tools and therapeutic strategies. This study conducted a comparative analysis of 632 Mycobacterium genomes obtained from the public database Bacterial and Viral Bioinformatics Resource Center (BV-BRC). The analysis focused on Mycobacterium tuberculosis (Mtb) and NTM. Techniques included comparative genome an
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Chapman, Stephen J., Grace V. Robinson, Rahul Shrimanker, Chris D. Turnbull, and John M. Wrightson. "Respiratory infection—mycobacterial." In Oxford Handbook of Respiratory Medicine, edited by Stephen J. Chapman, Grace V. Robinson, Rahul Shrimanker, Chris D. Turnbull, and John M. Wrightson. Oxford University Press, 2021. http://dx.doi.org/10.1093/med/9780198837114.003.0043.

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Includes: Tuberculosis: epidemiology and pathophysiology, first-line anti-TB drugs, TB chemotherapy with comorbid disease, multidrug-resistant TB (MDR-TB), latent TB infection, TB and anti-TNF-α‎ treatment, disseminated BCG infection (BCGosis), future developments in TB, non-tuberculous mycobacteria (NTM), NTM species and lung disease.
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Conference papers on the topic "Non-tuberculous Mycobacterium (NTM)"

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Graves, Jennifer, and Damian Downey. "Epidemiology And Treatment Of Non-tuberculous Mycobacterium (NTM) In Adult Cystic Fibrosis (CF) Patients." In American Thoracic Society 2010 International Conference, May 14-19, 2010 • New Orleans. American Thoracic Society, 2010. http://dx.doi.org/10.1164/ajrccm-conference.2010.181.1_meetingabstracts.a2340.

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Yioe, V., F. Frost, MJ Walshaw, and D. Wat. "S23 Sensitivity and specificity of radiological findings for non-tuberculous mycobacterium pulmonary disease (NTM-PD) in cystic fibrosis." In British Thoracic Society Winter Meeting 2018, QEII Centre, Broad Sanctuary, Westminster, London SW1P 3EE, 5 to 7 December 2018, Programme and Abstracts. BMJ Publishing Group Ltd and British Thoracic Society, 2018. http://dx.doi.org/10.1136/thorax-2018-212555.29.

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Teramoto, Shinji, and Nobuyuki Hizawa. "Influences Of The Huge Earthquake-Associated Disaster On The Clinical Symptoms And Radiographic Findings In Patients With Non-Tuberculous Mycobacterium (NTM)." In American Thoracic Society 2012 International Conference, May 18-23, 2012 • San Francisco, California. American Thoracic Society, 2012. http://dx.doi.org/10.1164/ajrccm-conference.2012.185.1_meetingabstracts.a4037.

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Hosein, A. S., S. Blanton-Rich, J. J. H. Gan, et al. "Non-Tuberculous Mycobacterium (NTM): An 11-year Retrospective Review in Ayrshire and Arran: A Rural/Semi-urban Population on the West Coast of Scotland." In American Thoracic Society 2024 International Conference, May 17-22, 2024 - San Diego, CA. American Thoracic Society, 2024. http://dx.doi.org/10.1164/ajrccm-conference.2024.209.1_meetingabstracts.a3181.

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Ibrahim, J., A. Ali, M. Mahmoud, et al. "Non-Tuberculous Mycobacteria (NTM): A Review of Local Prevalence and Management of Pulmonary NTM." In American Thoracic Society 2019 International Conference, May 17-22, 2019 - Dallas, TX. American Thoracic Society, 2019. http://dx.doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a2049.

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Gonzalez Quero, Beatriz, Eva Tabernero Huguet, Lander Altube, et al. "Treatment outcomes of non tuberculous mycobacterial (NTM) pulmonary disease. Multicenter study." In ERS International Congress 2020 abstracts. European Respiratory Society, 2020. http://dx.doi.org/10.1183/13993003.congress-2020.2798.

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Agarwal, Sushil, Sven Lehm, Deborah Beech, and Amanda Middleton. "Prevalence Of Non-Tuberculous Mycobacteria (NTM) In Stoke-On-Trent, UK." In American Thoracic Society 2011 International Conference, May 13-18, 2011 • Denver Colorado. American Thoracic Society, 2011. http://dx.doi.org/10.1164/ajrccm-conference.2011.183.1_meetingabstracts.a3327.

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Quero, Beatriz Gonzalez, Eva Tabernero Huguet, Patricia Sobradillo Ecenarro, et al. "PREVALENCE OF NON TUBERCULOUS MYCOBACTERIA (NTM) IN HIGH RISK COPD PATIENTS." In ERS International Congress 2021 abstracts. European Respiratory Society, 2021. http://dx.doi.org/10.1183/13993003.congress-2021.pa3093.

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Villar Hernández, Raquel, Irene Latorre, Zoran Stojanovic, et al. "Late Breaking Abstract - Use of non-tuberculous mycobacteria (NTM) specific antigens to detect NTM infection." In ERS International Congress 2019 abstracts. European Respiratory Society, 2019. http://dx.doi.org/10.1183/13993003.congress-2019.oa5139.

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Danelishvili, L., R. Vande Voorde, and E. Dzalamidze. "Identification of Small Molecule Inhibitors Against Non-Tuberculous Mycobacteria (NTM) in Activated Macrophages." In American Thoracic Society 2022 International Conference, May 13-18, 2022 - San Francisco, CA. American Thoracic Society, 2022. http://dx.doi.org/10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a3871.

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