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Journal articles on the topic 'Non-viral gene transfer'

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1

Wolff, Jon. "Non-Viral Gene Transfer." Nature Biotechnology 17, S4 (1999): 9. http://dx.doi.org/10.1038/70119.

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2

Lechardeur, Delphineq, and Gergely Lukacs. "Intracellular Barriers to Non-Viral Gene Transfer." Current Gene Therapy 2, no. 2 (2002): 183–94. http://dx.doi.org/10.2174/1566523024605609.

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3

Peeters, L., N. N. Sanders, J. Demeester, and S. C. De Smedt. "Challenges in non-viral ocular gene transfer." Biochemical Society Transactions 35, no. 1 (2007): 47–49. http://dx.doi.org/10.1042/bst0350047.

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Nowadays, there is no effective treatment for many retinal disorders. Knowledge of the genetic basis of many severe ocular diseases may allow for alternative treatments by gene therapy. Non-viral gene complexes, such as lipo- and poly-plexes, can be delivered to the posterior segment, most often the target tissue, by intravitreal or subretinal injection. Since subretinal injections are very invasive, intravitreal injection is a promising alternative route to deliver gene complexes into the eye. However, the drawback of this technique is the relative long distance the complexes have to travel t
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4

Haupt, Gerald, and Angela Haupt. "963: Non Viral Gene Transfer by Jet Injection." Journal of Urology 171, no. 4S (2004): 255. http://dx.doi.org/10.1016/s0022-5347(18)38200-4.

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5

Ziady, Assem G., Pamela B. Davis, and Michael W. Konstan. "Non-viral gene transfer therapy for cystic fibrosis." Expert Opinion on Biological Therapy 3, no. 3 (2003): 449–58. http://dx.doi.org/10.1517/14712598.3.3.449.

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6

George, Andrew J. T. "PEPTIDE-MEDIATED NON-VIRAL GENE TRANSFER FOR TRANSPLANTATION." Transplantation 69, no. 6 (2000): 1031–33. http://dx.doi.org/10.1097/00007890-200003270-00001.

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7

Abdallah, Bassima, Laurent Sachs, and Barbara A. Demeneix. "Non-viral gene transfer: Applications in developmental biology and gene therapy." Biology of the Cell 85, no. 1 (1995): 1–7. http://dx.doi.org/10.1111/j.1768-322x.1995.tb00937.x.

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8

Matsuno, Yukihiro, Hisashi Iwata, Yukio Umeda, Hisato Takagi, Yoshio Mori, and Hajime Hirose. "NON-VIRAL GENE GUN-MEDIATED GENE TRANSFER INTO THE BEATING HEART." ASAIO Journal 48, no. 2 (2002): 188. http://dx.doi.org/10.1097/00002480-200203000-00248.

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9

Elmer, Jacob J., Matthew D. Christensen, and Kaushal Rege. "Applying horizontal gene transfer phenomena to enhance non-viral gene therapy." Journal of Controlled Release 172, no. 1 (2013): 246–57. http://dx.doi.org/10.1016/j.jconrel.2013.08.025.

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10

NIKOL, S. "Viral or non-viral angiogenesis gene transfer—New answers to old questions." Cardiovascular Research 73, no. 3 (2007): 443–45. http://dx.doi.org/10.1016/j.cardiores.2006.12.005.

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11

Chen, Ying, Huai Yu Wang, and Mei Zhang. "Study of Non-Viral Gene Transfer of NB4 Cells." Advanced Materials Research 341-342 (September 2011): 333–37. http://dx.doi.org/10.4028/www.scientific.net/amr.341-342.333.

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Post-Transcriptional Gene Silencing and RNA interference (RNAi) are terms describing the specific suppression of genes by complementary dsRNA. High-efficiency transfection is an essential first step for achieving effective gene knockdown. Non-viral transfection include chemical-transfection and electrotransfection. For a particular cell line, select the appropriate transfection method is very important. In this study, we compared a variety of commercially available reagents and electrotransfection, approaches to define methods for efficient delivery of siRNA to NB4 cells. Fluorescently-labelle
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12

OKU, N. "A novel non-viral gene transfer system, polycation liposomes." Advanced Drug Delivery Reviews 52, no. 3 (2001): 209–18. http://dx.doi.org/10.1016/s0169-409x(01)00212-5.

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13

Wagstaff, Kylie M., and David A. Jans. "Nucleocytoplasmic transport of DNA: enhancing non-viral gene transfer." Biochemical Journal 406, no. 2 (2007): 185–202. http://dx.doi.org/10.1042/bj20070505.

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Gene therapy, the correction of dysfunctional or deleted genes by supplying the lacking component, has long been awaited as a means to permanently treat or reverse many genetic disorders. To achieve this, therapeutic DNA must be delivered to the nucleus of cells using a safe and efficient delivery vector. Although viral-based vectors have been utilized extensively due to their innate ability to deliver DNA to intact cells, safety considerations, such as pathogenicity, oncogenicity and the stimulation of an immunological response in the host, remain problematical. There has, however, been much
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14

Dass, Crispin R., and Peter F. M. Choong. "Non-viral methods for gene transfer towards osteosarcoma therapy." Journal of Drug Targeting 15, no. 3 (2007): 184–89. http://dx.doi.org/10.1080/10611860701231547.

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15

Davis, Pamela B., and Assem G. Ziady. "Non-viral methods of gene transfer to airway epithelium." Gene Therapy and Regulation 2, no. 1 (2003): 77–90. http://dx.doi.org/10.1163/156855803762295440.

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16

Bansal, Aparna, and Himanshu. "Non-Viral Vectors for Gene Delivery." Nanoscience &Nanotechnology-Asia 9, no. 1 (2018): 4–11. http://dx.doi.org/10.2174/2210681208666180110154233.

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Introduction: Gene therapy has emerged out as a promising therapeutic pave for the treatment of genetic and acquired diseases. Gene transfection into target cells using naked DNA is a simple and safe approach which has been further improved by combining vectors or gene carriers. Both viral and non-viral approaches have achieved a milestone to establish this technique, but non-viral approaches have attained a significant attention because of their favourable properties like less immunotoxicity and biosafety, easy to produce with versatile surface modifications, etc. Literature is rich in eviden
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17

Godbey, W. T., and A. G. Mikos. "Recent progress in gene delivery using non-viral transfer complexes." Journal of Controlled Release 72, no. 1-3 (2001): 115–25. http://dx.doi.org/10.1016/s0168-3659(01)00267-x.

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18

Gresch, O. "New non-viral method for gene transfer into primary cells." Methods 33, no. 2 (2004): 151–63. http://dx.doi.org/10.1016/j.ymeth.2003.11.009.

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19

Xenariou, Stefania, Hai-Dong Liang, Uta Griesenbach, et al. "695. Low-Frequency Ultrasound Increases Non- Viral Lung Gene Transfer." Molecular Therapy 13 (2006): S269. http://dx.doi.org/10.1016/j.ymthe.2006.08.773.

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20

Naash, Muna I., Ron M. Ballard, Jeff Skaggs, et al. "882. Non-Viral Ocular Gene Transfer for Hereditary Retinal Degeneration." Molecular Therapy 13 (2006): S340. http://dx.doi.org/10.1016/j.ymthe.2006.08.971.

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21

Chan, Chee‐Kai, and David A. Jans. "Using nuclear targeting signals to enhance non‐viral gene transfer." Immunology & Cell Biology 80, no. 2 (2002): 119–30. http://dx.doi.org/10.1046/j.1440-1711.2002.01061.x.

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22

Farjo, Rafal, Jeff Skaggs, Alexander B. Quiambao, Mark J. Cooper, and Muna I. Naash. "Efficient Non-Viral Ocular Gene Transfer with Compacted DNA Nanoparticles." PLoS ONE 1, no. 1 (2006): e38. http://dx.doi.org/10.1371/journal.pone.0000038.

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23

Wilson, Matthew H., and Michael E. DeBakey. "320: Non-Viral Gene Transfer for Renal Disease and Complications." American Journal of Kidney Diseases 55, no. 4 (2010): B111. http://dx.doi.org/10.1053/j.ajkd.2010.02.327.

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24

Passineau, M. J., L. Zourelias, L. Machen, P. C. Edwards, and R. L. Benza. "Ultrasound-assisted non-viral gene transfer to the salivary glands." Gene Therapy 17, no. 11 (2010): 1318–24. http://dx.doi.org/10.1038/gt.2010.86.

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25

Vincent, M., I. de Lázaro, and K. Kostarelos. "Graphene materials as 2D non-viral gene transfer vector platforms." Gene Therapy 24, no. 3 (2016): 123–32. http://dx.doi.org/10.1038/gt.2016.79.

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26

LECHARDEUR, D., A. VERKMAN, and G. LUKACS. "Intracellular routing of plasmid DNA during non-viral gene transfer." Advanced Drug Delivery Reviews 57, no. 5 (2005): 755–67. http://dx.doi.org/10.1016/j.addr.2004.12.008.

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27

Shettima, Abubakar, Muhammad M. Ibrahim, and Musa Ibn Abbas. "Features and properties of viral and non-viral gene delivery systems towards effective gene therapy." International Journal of Medicine 5, no. 1 (2017): 45. http://dx.doi.org/10.14419/ijm.v5i1.7189.

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Gene therapy has revolutionized the treatment of hereditary and genetic link disorders by consciously swapping, fixing, adding or deleting the genetic sequences responsible for the condition. The culprit cells are altered by inserting purposeful genes and incorporated into their genome for proper expression. Germ line therapy ensures the genotypic changes to be transferred to the next generation (offspring) while the somatic type adequately rest on corrective pedestals and as such not advantageous to the offspring. The earlier was constrained by technical difficulties as well as ethical consid
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28

Nakanishi, Mahito, Akiko Eguchi, Teruo Akuta, et al. "Basic Peptides as Functional Components of Non-viral Gene Transfer Vehicles." Current Protein & Peptide Science 4, no. 2 (2003): 141–50. http://dx.doi.org/10.2174/1389203033487234.

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29

Jeschke, M., D. Herndon, W. Bare, R. Barrow, and K. Jauch. "Possibilities of Non-Viral Gene Transfer to Improve Cutaneous Wound Healing." Current Gene Therapy 1, no. 3 (2001): 267–78. http://dx.doi.org/10.2174/1566523013348571.

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30

FUMOTO, Shintaro. "Organ-, Region- and Cell-Selective Gene Transfer Using Non-Viral Vectors." YAKUGAKU ZASSHI 129, no. 9 (2009): 1055–61. http://dx.doi.org/10.1248/yakushi.129.1055.

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31

Johansson, A., C. Möller, P. Gellerfors, and P. Harper. "Non-viral mediated gene transfer of porphobilinogen deaminase into mammalian cells." Scandinavian Journal of Clinical and Laboratory Investigation 62, no. 2 (2002): 105–13. http://dx.doi.org/10.1080/003655102753611726.

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32

Passineau, M. J., L. Zourelias, L. Machen, P. C. Edwards, and R. L. Benza. "Erratum: Ultrasound-assisted non-viral gene transfer to the salivary glands." Gene Therapy 18, no. 4 (2011): 424. http://dx.doi.org/10.1038/gt.2011.30.

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33

Saadi, Hogir. "Gene Therapy Approaches." Qubahan Academic Journal 1, no. 1 (2021): 52–56. http://dx.doi.org/10.48161/qaj.v1n1a35.

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Gene therapy can be described broadly as the transfer of genetic material to control a disease or at least to enhance a patient's clinical status. The transformation of viruses into genetic shuttles is one of the core principles of gene therapy, which will introduce the gene of interest into the target tissue and cells. To do this, safe strategies have been invented, using many viral and non-viral vector delivery. Two major methods have emerged: modification in vivo and modification ex vivo. For gene therapeutic approaches which are focused on lifelong expression of the therapeutic gene, retro
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34

Scheller, E. L., and P. H. Krebsbach. "Gene Therapy: Design and Prospects for Craniofacial Regeneration." Journal of Dental Research 88, no. 7 (2009): 585–96. http://dx.doi.org/10.1177/0022034509337480.

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Gene therapy is defined as the treatment of disease by transfer of genetic material into cells. This review will explore methods available for gene transfer as well as current and potential applications for craniofacial regeneration, with emphasis on future development and design. Though non-viral gene delivery methods are limited by low gene transfer efficiency, they benefit from relative safety, low immunogenicity, ease of manufacture, and lack of DNA insert size limitation. In contrast, viral vectors are nature’s gene delivery machines that can be optimized to allow for tissue-specific targ
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35

Sayeed-Shah, U. "Non-viral Gene Transfer in Porcine Myocardium Enhanced by Transmyocardial Laser Revascularization." Journal of the American College of Cardiology 31, no. 2 (1998): 3A. http://dx.doi.org/10.1016/s0735-1097(97)83740-0.

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36

Sayeed-Shah, U., M. J. Mann, S. Grachev, et al. "Non-viral gene transfer in porcine myocardium enhanced by transmyocardial laser revascularization." Journal of the American College of Cardiology 31 (1998): 3. http://dx.doi.org/10.1016/s0735-1097(98)80679-7.

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37

Beshay, Morris, Amiq Gazdhar, Mathias Gugger, Marc Reymond, and Ralph A. Schmid. "The feasibility of non-viral gene transfer to the diaphragm in vivo." Development, Growth & Differentiation 51, no. 6 (2009): 547–53. http://dx.doi.org/10.1111/j.1440-169x.2009.01117.x.

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38

Aliño, Salvador F., Ester Escrig, Fernando Revert, Vicent M. Guillem, and Antonio Crespo. "Pharmacodynamic approach to study the gene transfer process employing non-viral vectors." Biochemical Pharmacology 60, no. 12 (2000): 1845–53. http://dx.doi.org/10.1016/s0006-2952(00)00503-7.

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39

Xenariou, S., H. D. Liang, U. Griesenbach, et al. "Low-frequency ultrasound increases non-viral gene transfer to the mouse lung." Acta Biochimica et Biophysica Sinica 42, no. 1 (2009): 45–51. http://dx.doi.org/10.1093/abbs/gmp100.

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40

Gurwitz, David. "Non-viral gene transfer: liposomes and nanospheres promise to deliver the goods." Molecular Medicine Today 4, no. 11 (1998): 464. http://dx.doi.org/10.1016/s1357-4310(98)01362-8.

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41

Zhang, Yun, Felix Schlachetzki, and William M. Pardridge. "Global non-viral gene transfer to the primate brain following intravenous administration." Molecular Therapy 7, no. 1 (2003): 11–18. http://dx.doi.org/10.1016/s1525-0016(02)00018-7.

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42

Singh, Harjeet, Mary Helen Huls, Matthew J. Figliola, et al. "278. Next-Generation Non-Viral Gene Transfer to Redirect T-Cell Specificity." Molecular Therapy 24 (May 2016): S110—S111. http://dx.doi.org/10.1016/s1525-0016(16)33087-8.

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43

Dhaliwal, Anandika, Jonathan Lam, Maricela Maldonado, Clayton Lin, and Tatiana Segura. "Extracellular matrix modulates non-viral gene transfer to mouse mesenchymal stem cells." Soft Matter 8, no. 5 (2012): 1451–59. http://dx.doi.org/10.1039/c1sm06591b.

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44

Li, D., G. P. Tang, J. Z. Li, et al. "Dual-targeting non-viral vector based on polyethylenimine improves gene transfer efficiency." Journal of Biomaterials Science, Polymer Edition 18, no. 5 (2007): 545–60. http://dx.doi.org/10.1163/156856207780852532.

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45

Jeschke, M. G., R. E. Barrow, W. Baer, G. Richter, K. Jauch, and D. N. Herndon. "Non-viral, Liposmal KGF Gene Transfer Improves Wound Healing After Thermal Injury." Journal of Burn Care & Rehabilitation 22 (March 2001): S49. http://dx.doi.org/10.1097/00004630-200103002-00010.

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46

Griesenbach, Uta, Cuixiang Meng, Raymond Farley, et al. "The role of doxorubicin in non-viral gene transfer in the lung." Biomaterials 30, no. 10 (2009): 1971–77. http://dx.doi.org/10.1016/j.biomaterials.2008.12.037.

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47

Zhang, Yun, Yuntao Wang, Ruben J. Boado, and William M. Pardridge. "Lysosomal Enzyme Replacement of the Brain with Intravenous Non-Viral Gene Transfer." Pharmaceutical Research 25, no. 2 (2007): 400–406. http://dx.doi.org/10.1007/s11095-007-9357-6.

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48

Miyake, Koichi, and Takashi Shimada. "Gene therapy and viral vectors. Gene transfer into non-dividing cells by a lentiviral vector." Uirusu 47, no. 2 (1997): 213–19. http://dx.doi.org/10.2222/jsv.47.213.

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49

Dieterlen, Maja-Theresa, Florian Wegner, Sigrid C. Schwarz, et al. "Non-viral gene transfer by nucleofection allows stable gene expression in human neural progenitor cells." Journal of Neuroscience Methods 178, no. 1 (2009): 15–23. http://dx.doi.org/10.1016/j.jneumeth.2008.11.007.

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50

Mastorakos, P., C. Zhang, S. Berry, et al. "ET-38 * BRAIN PENETRATING NON-VIRAL GENE VECTORS FOR EFFICIENT GENE TRANSFER TO BRAIN TUMORS." Neuro-Oncology 16, suppl 5 (2014): v87—v88. http://dx.doi.org/10.1093/neuonc/nou255.38.

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