Academic literature on the topic 'Noncancer hyperplasia'

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Journal articles on the topic "Noncancer hyperplasia"

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Qu, Yinsheng, Bao-Ling Adam, Yutaka Yasui, et al. "Boosted Decision Tree Analysis of Surface-enhanced Laser Desorption/Ionization Mass Spectral Serum Profiles Discriminates Prostate Cancer from Noncancer Patients." Clinical Chemistry 48, no. 10 (2002): 1835–43. http://dx.doi.org/10.1093/clinchem/48.10.1835.

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Abstract Background: The low specificity of the prostate-specific antigen (PSA) test makes it a poor biomarker for early detection of prostate cancer (PCA). Because single biomarkers most likely will not be found that are expressed by all genetic forms of PCA, we evaluated and developed a proteomic approach for the simultaneous detection and analysis of multiple proteins for the differentiation of PCA from noncancer patients. Methods: Serum samples from 386 men [197 with PCA, 92 with benign prostatic hyperplasia (BPH), and 96 healthy individuals], randomly divided into training (n = 326) and t
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Miao, Yingying, Hui Tang, Qizhi Zhai, et al. "Gut Microbiota Dysbiosis in the Development and Progression of Gastric Cancer." Journal of Oncology 2022 (August 28, 2022): 1–15. http://dx.doi.org/10.1155/2022/9971619.

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Objectives. This study aims to explore gut microbiota dysbiosis in the histological stages of gastric cancer (GC). Methods. Feces samples and clinical characteristics were collected from patients with different stages of GC, including 15 superficial gastritis (SG), 13 atrophic gastritis (AG), 8 gastric mucosal atypical hyperplasia (GMAH), and 15 advanced GC cases. The diversity and composition of gut microbiota among the four groups were determined by sequencing the V4 region of bacterial 16S rRNA genes. Results. Reduced gut microbial alpha diversity and altered dissimilarity of the microbial
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Nurmikko, Pauliina, Kim Pettersson, Timo Piironen, Jonas Hugosson, and Hans Lilja. "Discrimination of Prostate Cancer from Benign Disease by Plasma Measurement of Intact, Free Prostate-specific Antigen Lacking an Internal Cleavage Site at Lys145-Lys146." Clinical Chemistry 47, no. 8 (2001): 1415–23. http://dx.doi.org/10.1093/clinchem/47.8.1415.

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Abstract Background: The proportion of free prostate-specific antigen (PSA) is higher in the sera of patients with benign prostatic hyperplasia compared with patients with prostate cancer (PCa). We developed an immunoassay that measures intact, free PSA forms (fPSA-I), but does not detect free PSA that has been internally cleaved at Lys145-Lys146 (fPSA-N), and investigated whether this form could discriminate patients with PCa from those without PCa. Methods: The assay for fPSA-I uses a novel monoclonal antibody (MAb) that does not detect PSA that has been internally cleaved at Lys145-Lys146.
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Qian, Su-Ting, Hao-Yu Zhao, Fei-Fei Xie, Qing-Sheng Liu, and Dan-Li Cai. "Streptococcus anginosus in the development and treatment of precancerous lesions of gastric cancer." World Journal of Gastrointestinal Oncology 16, no. 9 (2024): 3771–80. http://dx.doi.org/10.4251/wjgo.v16.i9.3771.

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The microbiota is strongly association with cancer. Studies have shown significant differences in the gastric microbiota between patients with gastric cancer (GC) patients and noncancer patients, suggesting that the microbiota may play a role in the development of GC. Although Helicobacter pylori (H. pylori ) infection is widely recognized as a primary risk factor for GC, recent studies based on microbiota sequencing technology have revealed that non-H. pylori microbes also have a significant impact on GC. A recent study discovered that Streptococcus anginosus (S. anginosus ) is more prevalent
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Fredsøe, Jacob, Anne K. I. Rasmussen, Emma B. Laursen, et al. "Independent Validation of a Diagnostic Noninvasive 3-MicroRNA Ratio Model (uCaP) for Prostate Cancer in Cell-Free Urine." Clinical Chemistry 65, no. 4 (2019): 540–48. http://dx.doi.org/10.1373/clinchem.2018.296681.

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Abstract BACKGROUND Detection of prostate cancer (PC) based on serum prostate-specific antigen (PSA) testing leads to many unnecessary prostate biopsies, overdiagnosis, and overtreatment of clinically insignificant tumors. Thus, novel and more accurate molecular biomarkers are required. METHODS Using reverse transcription quantitative PCR, we measured the concentrations of 45 preselected microRNAs (miRNAs) in extracellular vesicle-enriched cell-free urine samples from 4 independent patient cohorts from Spain and Denmark, including 758 patients with clinically localized PC, 289 noncancer contro
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Gong, Yu, and Wenhua Fu. "Reversible role of MIR654/3P and MIR9/3P in pathogenesis of Epstein-Barr Virus negative, but not positive, Burkitt’s lymphoma." Journal of Leukocyte Biology, October 24, 2024. http://dx.doi.org/10.1093/jleuko/qiae237.

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Abstract The role of MIR654 in Burkitt’s lymphoma (BL) and whether it impacts expression of MYC, and its downstream activated MIR9 is not known. Expression of MYC, MYCN, MYCL, MIR9/3P, MIR654/5P, and MIR654/3P were assessed by qRT-PCR in biopsy samples from Epstein-Barr virus (EBV)- and EBV+ BL patients and BL cell lines. Effects of modulation of MIR9/3P and MIR654/3P on cell proliferation, apoptosis and chemosensitivity were evaluated. Luciferase reporter assay was performed to validate putative target of MIR654/5P. Effects of MIR9/3P and MIR654/3P on tumor burden and disease outcome were eva
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Dissertations / Theses on the topic "Noncancer hyperplasia"

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Волохова, Т. Ю., Володимир Віталійович Сікора, Владимир Витальевич Сикора та Volodymyr Vitaliiovych Sikora. "Застосування фокусину (тамсулозин) у лікуванні доброякісної гіперплазії переміхурової залози". Thesis, Видавництво СумДУ, 2009. http://essuir.sumdu.edu.ua/handle/123456789/5999.

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Мета дослідження: оцінити клінічну ефективність та безпеку Фокусину(виробництва компанії «Зентіва») у хворих з ДГПЗ. При цитуванні документа, використовуйте посилання http://essuir.sumdu.edu.ua/handle/123456789/5999
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