Academic literature on the topic 'Nonreplicative recombination'

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Journal articles on the topic "Nonreplicative recombination"

1

Gmyl, Anatoly P., Evgeny V. Belousov, Svetlana V. Maslova, Elena V. Khitrina, Alexander B. Chetverin, and Vadim I. Agol. "Nonreplicative RNA Recombination in Poliovirus." Journal of Virology 73, no. 11 (1999): 8958–65. http://dx.doi.org/10.1128/jvi.73.11.8958-8965.1999.

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ABSTRACT Current models of recombination between viral RNAs are based on replicative template-switch mechanisms. The existence of nonreplicative RNA recombination in poliovirus is demonstrated in the present study by the rescue of viable viruses after cotransfections with different pairs of genomic RNA fragments with suppressed translatable and replicating capacities. Approximately 100 distinct recombinant genomes have been identified. The majority of crossovers occurred between nonhomologous segments of the partners and might have resulted from transesterification reactions, not necessarily i
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2

Silberstein, Z., M. Shalit, and A. Cohen. "Heteroduplex strand-specificity in restriction-stimulated recombination by the RecE pathway of Escherichia coli." Genetics 133, no. 3 (1993): 439–48. http://dx.doi.org/10.1093/genetics/133.3.439.

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Abstract The RecE recombination pathway is active in Escherichia coli recB recC sbcA mutants. To isolate and characterize products and intermediates of RecE-mediated, break-induced, intramolecular recombination, we infected recB recC sbcA mutants, expressing EcoRI endonuclease, with chimeric lambda phages that allow EcoRI-mediated release of cloned linear recombination substrates. Substrates with direct terminal repeats recombined to yield a circular product with one copy of the repeated sequence. Some recombinants were heteroallelic for the recombining markers. Markers distant to the break we
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3

Agol, Vadim I. "Existence and significance of viral nonreplicative RNA recombination." PLOS Biology 21, no. 7 (2023): e3002216. http://dx.doi.org/10.1371/journal.pbio.3002216.

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4

GMYL, A. P. "Nonreplicative homologous RNA recombination: Promiscuous joining of RNA pieces?" RNA 9, no. 10 (2003): 1221–31. http://dx.doi.org/10.1261/rna.5111803.

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5

Kim, Hyejeong, David Aponte-Diaz, Mohamad S. Sotoudegan, Djoshkun Shengjuler, Jamie J. Arnold, and Craig E. Cameron. "The enterovirus genome can be translated in an IRES-independent manner that requires the initiation factors eIF2A/eIF2D." PLOS Biology 21, no. 1 (2023): e3001693. http://dx.doi.org/10.1371/journal.pbio.3001693.

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RNA recombination in positive-strand RNA viruses is a molecular-genetic process, which permits the greatest evolution of the genome and may be essential to stabilizing the genome from the deleterious consequences of accumulated mutations. Enteroviruses represent a useful system to elucidate the details of this process. On the biochemical level, it is known that RNA recombination is catalyzed by the viral RNA-dependent RNA polymerase using a template-switching mechanism. For this mechanism to function in cells, the recombining genomes must be located in the same subcellular compartment. How a v
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6

Popov, N. N., T. Yu. Kolotova, and M. B. Davidenko. "Mechanisms and regulation of rna virus recombination." Annals of Mechnikov Institute, no. 3 (October 1, 2017): 7–17. https://doi.org/10.5281/zenodo.1000128.

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This review attempts to summarize the most important data concerning of molecular mechanisms and regulation of the viral recombination. Two mechanisms are responsible for RNA virus recombination, specifically replicative recombination based on replicase template switching and nonreplicative joining among fragments of viral origin. Retroviruses recombination occurs during DNA synthesis, whereby reverse transcriptase undergoes template switching between the two copackaged RNAs, However numerous questions about molecular mechanisms of RNA recombination remain unanswered. RNA recombination is one
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7

Raju, R., S. V. Subramaniam, and M. Hajjou. "Genesis of Sindbis virus by in vivo recombination of nonreplicative RNA precursors." Journal of virology 69, no. 12 (1995): 7391–401. http://dx.doi.org/10.1128/jvi.69.12.7391-7401.1995.

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8

Dooner, Hugo K., and Isabel M. Martínez-Férez. "Germinal Excisions of the Maize Transposon Activator Do Not Stimulate Meiotic Recombination or Homology-Dependent Repair at the bz Locus." Genetics 147, no. 4 (1997): 1923–32. http://dx.doi.org/10.1093/genetics/147.4.1923.

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Abstract Double-strand breaks have been implicated both in the initiation of meiotic recombination in yeast and as intermediates in the transposition process of nonreplicative transposons. Some transposons of this class, notably P of Drosophila and Tc1 of Caenorhabditis elegans, promote a form of homology-dependent premeiotic gene conversion upon excision. In this work, we have looked for evidence of an interaction between Ac transposition and meiotic recombination at the bz locus in maize. We find that the frequency of meiotic recombination between homologues is not enhanced by the presence o
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9

Hagemann, A. T., and N. L. Craig. "Tn7 transposition creates a hotspot for homologous recombination at the transposon donor site." Genetics 133, no. 1 (1993): 9–16. http://dx.doi.org/10.1093/genetics/133.1.9.

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Abstract Homologous recombination at the bacterial transposon Tn7 donor site is stimulated 10-fold when Tn7 is activated to transpose at high frequency in RecD- Escherichia coli, where recombination is focused near the ends of double-chain breaks. This is observed as an increase in recombination between two lacZ heteroalleles when one copy of lacZ carries within it a Tn7 that is transposing at high frequency. This stimulation of recombination is dependent upon the presence of homology with the donor site, is independent of SOS induction, and is not due to a global stimulation of recombination.
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10

Middendorf, Barbara, Bianca Hochhut, Kristina Leipold, Ulrich Dobrindt, Gabriele Blum-Oehler, and Jörg Hacker. "Instability of Pathogenicity Islands in Uropathogenic Escherichia coli 536." Journal of Bacteriology 186, no. 10 (2004): 3086–96. http://dx.doi.org/10.1128/jb.186.10.3086-3096.2004.

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ABSTRACT The uropathogenic Escherichia coli strain 536 carries at least five genetic elements on its chromosome that meet all criteria characteristic of pathogenicity islands (PAIs). One main feature of these distinct DNA regions is their instability. We applied the so-called island-probing approach and individually labeled all five PAIs of E. coli 536 with the counterselectable marker sacB to evaluate the frequency of PAI-negative colonies under the influence of different environmental conditions. Furthermore, we investigated the boundaries of these PAIs. According to our experiments, PAI II5
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