Log in

Relevant bibliographies by topics / Nootropic activity / Journal articles

To see the other types of publications on this topic, follow the link: Nootropic activity.

Journal articles on the topic 'Nootropic activity'

Author: Grafiati

Published: 4 June 2025

Last updated: 1 August 2025

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the top 50 journal articles for your research on the topic 'Nootropic activity.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Browse journal articles on a wide variety of disciplines and organise your bibliography correctly.

1

Ugwu, Anthony Odinaka, Oliver Asogwa Patrick, Nathaniel Kumar Sarella Prakash, Samuel Otuodi1 Asogwa, and Kakarparthy Ravishankar. "Nootropic Activity of Ethanolic Extract of Zingiber officinale and Centella asiatica on Stress Induced Rats." International Journal of Current Science Research and Review 06, no. 06 (2023): 3240–45. https://doi.org/10.5281/zenodo.8025900.

Full text

Abstract:

<strong>ABSTRACT: </strong>Nootropics, natural or synthetic substances that boost brain function and cognitive abilities, were investigated in this study. Specifically, the effects of <em>Zingiber officinale</em> and <em>Centella asiatica</em> extracts were compared to the standard nootropic piracetam. Both plant extracts demonstrated nootropic activity and contained phytochemicals like flavonoids, tannins, and saponins that protect the brain from oxidative damage. Sterols such as stigmasterol inhibiting acetyl CoA esterase activity were also present. Tests were conducted on rats given the ext

APA, Harvard, Vancouver, ISO, and other styles

2

Shabanov, P. D. "The Origins and Background of the Creation of the Nootropics Concept." Нейрохимия 40, no. 2 (2023): 101–7. http://dx.doi.org/10.31857/s1027813323020127.

Full text

Abstract:

The concept of nootropics was introduced into pharmacology in the early 1970s by Corneliu Giurgea, a Belgian pharmacologist of Romanian origin, based on the study of 2-oxo-1-pyrrolidine derivatives, which later became known as racetams. The paper substantiates the position that the emergence of modern ideas about nootropics and similar compounds (psychoenergizers, antihypoxants, actoprotectors) in a certain sense was preceded by the concept of adaptogens by N.V. Lazarev (1953–1958), whose theoretical development went towards concretization of certain provisions of this concept. The formation o

APA, Harvard, Vancouver, ISO, and other styles

3

Dr., G.Nagaraju, Sirisha V., Ramakrishna Kavati, and Hareesh Dara Dr. "DETERMINATION OF NOOTROPIC ACTIVITY AND ANTI BACTERIAL ACTIVITY OF FICUS CARICA." Journal of Pharma Research 09, no. 12 (2020): 156–61. https://doi.org/10.5281/zenodo.14241693.

Full text

Abstract:

<strong><em>ABSTRACT</em></strong> <strong><em> </em></strong>  <strong>Objective:</strong> To evaluate the Nootropic and anti bacterial activity of Ficus Carica (F.Carica)   <strong>Materials and Methods</strong>: Ethanolic extract of F. Carica was utilized to assess nootropic activity, result of extract on studying as well as remembrance in mice was assessed by utilizing the elevated plus maze model and In-vitro anti bacterial activitywascarriedoutbycupplatemethodsforestimationofzoneofinhibitionataconcentrationof50,100,150and200μg/ml.   <strong>Results:</strong> The ob

APA, Harvard, Vancouver, ISO, and other styles

4

Bhanumathy, M., M. S. Harish, H. N. Shivaprasad, and G. Sushma. "Nootropic activity ofCelastrus paniculatusseed." Pharmaceutical Biology 48, no. 3 (2010): 324–27. http://dx.doi.org/10.3109/13880200903127391.

Full text

APA, Harvard, Vancouver, ISO, and other styles

5

Parikshit, V. Choudhari, G. Kanse Vanita, Venkatachalam A., and R. Pal Punam. "Antidepressant and nootropic activity of aqueous extract of Bougainvillea glabra." World Journal of Advanced Research and Reviews 10, no. 1 (2021): 334–39. https://doi.org/10.5281/zenodo.4734597.

Full text

Abstract:

The aim of this analysis was to assess antidepressant & nootropic capacity of Bougainvillea Glabra aqueous extract (BGAE). Forced swim test, tail suspension test, & tetrabenazine mediated catalepsy & ptosis models were used to assess BGAE's antidepressant efficacy in mice at doses of 250 & 500 mg/kg orally. Morris water maze with elevated plus maze (EPM) was used to test nootropic behaviour. Normal medications for antidepressant & nootropic function were imipramine (25 mg/kg) & piracetam (300 mg/kg), respectively. Antioxidant assays such as DPPH & TBARS were use

APA, Harvard, Vancouver, ISO, and other styles

6

Navarro, Pau, Justyna Meissner, José Luis Mullor, Nuria Caturla, and Jonathan Jones. "Development of a Herb-Based Dietary Ingredient with Potential Nootropic Properties: From Bench to Bedside." Applied Sciences 14, no. 24 (2024): 11869. https://doi.org/10.3390/app142411869.

Full text

Abstract:

Cognitive decline is a natural process that occurs during aging. Several natural solutions called nootropics exist that can help mitigate this process. However, in some cases, there is a lack of scientific evidence on their potential mechanisms and efficacy. To this end, a total of nine different herb extracts with potential nootropic activity were evaluated. These herb extracts were tested in human neural stem cell cultures exposed to oxidative stress, where reactive oxygen/nitrogen species, cell survival and trophic factor expression were analyzed. Of these extracts, Salvia officinalis (sage

APA, Harvard, Vancouver, ISO, and other styles

7

Parikshit V. Choudhari, Vanita G. Kanse, A. Venkatachalam, and Punam R. Pal. "Antidepressant and nootropic activity of aqueous extract of Bougainvillea glabra." World Journal of Advanced Research and Reviews 10, no. 1 (2021): 334–39. http://dx.doi.org/10.30574/wjarr.2021.10.1.0163.

Full text

Abstract:

The aim of this analysis was to assess antidepressant & nootropic capacity of Bougainvillea Glabra aqueous extract (BGAE). Forced swim test, tail suspension test, & tetrabenazine mediated catalepsy & ptosis models were used to assess BGAE's antidepressant efficacy in mice at doses of 250 & 500 mg/kg orally. Morris water maze with elevated plus maze (EPM) was used to test nootropic behaviour. Normal medications for antidepressant & nootropic function were imipramine (25 mg/kg) & piracetam (300 mg/kg), respectively. Antioxidant assays such as DPPH & TBARS were used to

APA, Harvard, Vancouver, ISO, and other styles

8

Chikkamath, Vinuth, H. Venkatrao Kulkarni, V. Prasanna Habbu, and Nagappa Anantha Naik. "The effectiveness of Grewia hirsuta (Vahl.) as a nootropic on scopolamine-induced cognitive deficit in young and aged mice." Research Journal of Chemistry and Environment 28, no. 5 (2024): 30–40. http://dx.doi.org/10.25303/285rjce030040.

Full text

Abstract:

The dementia and loss of cognitive nature among humans are becoming epidemics and causing a socio-economic burden. Amnesia and cognitive behaviours are natural phenomena due to aging. The studies in young and aged mice were conducted in order to rule out the impact of aging. It has become necessary to find novel nootropic agents that are derived from natural resources. In synthetic drugs, we have a piracetam prototype nootropic. The natural products obtained from plant sources are safe and compatible with physiological conditions. Hence, we hope our scientific research may lead to novel nootro

APA, Harvard, Vancouver, ISO, and other styles

9

Anton, Semenets, Suleiman Marharyta, Georgiyants Victoriya, et al. "Theoretical justification of a purposeful search of potential neurotropic drugs." ScienceRise: Pharmaceutical Science, no. 4(26) (August 31, 2020): 4–17. https://doi.org/10.15587/2519-4852.2020.210042.

Full text

Abstract:

A targeted search for potential drugs of neurotropic action involves the choice of a basic “pharmacophore”, which is advisable to carry out on the basis of the achieved principle among the classes of chemical compounds where active pharmaceutical substances with high targeted activity have already been identified. Therefore, the pyrrolidine core, which is the basic fragment of nootropics of the racetam group, is promising for the rational design of biologically active compounds of nootropic action. Its combination with other heterocyclic fragments, in particular, the 1,2,4-triazole

APA, Harvard, Vancouver, ISO, and other styles

10

Golovko, T. V., V. A. Parshin, V. V. Asnina, et al. "Nootropic activity of ureidoacids and thiohydantoins." Pharmaceutical Chemistry Journal 24, no. 4 (1990): 260–63. http://dx.doi.org/10.1007/bf00764413.

Full text

APA, Harvard, Vancouver, ISO, and other styles

11

Tyurenkov, I. N., A. A. Ozerov, E. N. Shmatova, and Yu V. Archakova. "Nootropic Activity of Some Quinazoline Amides." Pharmaceutical Chemistry Journal 49, no. 2 (2015): 88–90. http://dx.doi.org/10.1007/s11094-015-1227-7.

Full text

APA, Harvard, Vancouver, ISO, and other styles

12

Makara, N. S., S. F. Gabdrakhmanova, T. A. Sapozhnikova, et al. "New (−)−Cytisine Derivatives with Nootropic Activity." Pharmaceutical Chemistry Journal 49, no. 5 (2015): 301–3. http://dx.doi.org/10.1007/s11094-015-1283-z.

Full text

APA, Harvard, Vancouver, ISO, and other styles

13

Chiriapkin, A. S., A. A. Glushko, and I. P. Kodonidi. "STUDY OF THE AFFINITY OF N-ACYL DERIVATIVES OF 2-OXO-1-PYRROLIDINE ACETAMIDE TO THE BINDING SITE OF NMDA RECEPTOR BY MOLECULAR DOCKING METHOD." Juvenis Scientia, no. 3 (2019): 4–6. http://dx.doi.org/10.32415/jscientia.2019.03.01.

Full text

Abstract:

The search for new compounds with а high nootropic biological activity is a promising scientific direction. A modern computational method for predicting pharmacological activity of the studied compounds is the molecular docking. The aim of this work is to study the affinity of new N-acyl derivatives of 2-oxo-1-pyrrolidine acetamide to the binding site of NMDA receptor to search of new effective nootropic drugs. As objects of study, there are used the new N-acyl derivatives of 2-oxo-1-pyrrolidine acetamide, racetams, glutamate and a virtual model of NMDA receptor of organism Rattus norvegicus w

APA, Harvard, Vancouver, ISO, and other styles

14

Vorontsova, O. N., A. G. Alyaeva, K. N. Koliasnikova, E. A. Valdman, and P. Yu Povarnina. "Neuropeptide cyclo-L-prolylglycine counteracts scopolamine-induced long-term memory impairment in rats in the novel object recognition test." Pharmacokinetics and Pharmacodynamics, no. 3 (November 3, 2023): 50–55. http://dx.doi.org/10.37489/2587-7836-2023-3-50-55.

Full text

Abstract:

Background. Cyclo-L-prolylglycine (CPG) was designed and synthesized at the V.V. Zakusov as a topological analogue of the classical nootrop piracetam and was further identiﬁed as an endogenous compound. Previously, the nootropic eﬀect of CPG was revealed in a model of retrograde amnesia in rats induced by electroconvulsive shock in the passive avoidance test (PAT).Objective. The aim of the present study was to investigate the nootropic eﬀect of CPG under more physiological conditions in the absence of strong stressors.Methods. Amnesia in rats was modeled by intraperitoneal (ip) administration

APA, Harvard, Vancouver, ISO, and other styles

15

Pathak (Sakhare), Leena. "Acute Toxicity Test and Nootropic Activity of Ethanolic Extract of Astragalus membranaceus Bunge on Scopolamine-Induced Amnesia in Rats." Journal of Drug Delivery and Therapeutics 12, no. 2 (2022): 11–18. http://dx.doi.org/10.22270/jddt.v12i2.5230.

Full text

Abstract:

The dried roots of Astragalus membranaceus Bunge, belongs to the family fabaceae enhances the memory function and this could be mediated through brain cholinergic system. Historically in China it is used as a medicine for treatment of different types of diseases. It gives good protection against aging and age related diseases. Astragalus membranaceus Bunge root extract was investigated to reveal its nootropic effect and acute toxicity study. The powdered roots were tested for the phytochemical constituents. Carbohydrates, proteins, amino acids, glycosides, saponins, volatile oils, alkaloids, s

APA, Harvard, Vancouver, ISO, and other styles

16

Malík, Matěj, and Pavel Tlustoš. "Nootropic Herbs, Shrubs, and Trees as Potential Cognitive Enhancers." Plants 12, no. 6 (2023): 1364. http://dx.doi.org/10.3390/plants12061364.

Full text

Abstract:

Plant-based nootropics are a diverse group of natural drugs that can improve cognitive abilities through various physiological mechanisms, especially in cases where these functions are weakened or impaired. In many cases, the nootropics enhance erythrocyte plasticity and inhibit aggregation, which improves the blood’s rheological properties and increases its flow to the brain. Many of these formulations possess antioxidant activity that protects brain tissue from neurotoxicity and improves the brain’s oxygen supply. They can induce the synthesis of neuronal proteins, nucleic acids, and phospho

APA, Harvard, Vancouver, ISO, and other styles

17

Chintawar, S. D., R. S. Somani, Veena S. Kasture, and S. B. Kasture. "Nootropic activity of Albizzia lebbeck in mice." Journal of Ethnopharmacology 81, no. 3 (2002): 299–305. http://dx.doi.org/10.1016/s0378-8741(02)00140-x.

Full text

APA, Harvard, Vancouver, ISO, and other styles

18

Petyunin, G. P., A. S. Zaks, V. N. Petyunina, Zh V. Dmitrievskaya, and T. A. Kapitonenko. "Synthesis and nootropic activity of oxamoylamino acids." Pharmaceutical Chemistry Journal 22, no. 11 (1988): 838–40. http://dx.doi.org/10.1007/bf00773611.

Full text

APA, Harvard, Vancouver, ISO, and other styles

19

Anikina, L. V., G. A. Gazieva, and A. N. Kravchenko. "Nootropic activity of N-(2-acetylaminoethyl)glycolurils." Russian Chemical Bulletin 69, no. 3 (2020): 563–66. http://dx.doi.org/10.1007/s11172-020-2799-2.

Full text

APA, Harvard, Vancouver, ISO, and other styles

20

Voronkov, A. V., S. A. Nigaryan, and D. I. Pozdnyakov. "STUDY OF HESPERIDINE AND CURKUMIN NOOTROPIC ACTIVITY UNDER THE CONDITIONS OF FOCAL CEREBRAL ISCHEMIA." Journal of Volgograd State Medical University 75, no. 3 (2020): 107–11. http://dx.doi.org/10.19163/1994-9480-2020-3(75)-107-111.

Full text

Abstract:

The article presents the results of the study of the nootropic activity of hesperidin and curcumin in conditions of focal cerebral ischemia. Studies were conducted on Wistar male rats, which reproduced the focal ischemia of the right middle cerebral artery. Experimental compounds and the reference drug (Mexidol) are administered intragastrally at the next day after surgery at a dosage of 100 mg/kg for three days. Researched using memory and cognitive assessment models – the method of avoiding passive (passive avoidance reaction) and active (TEA) environments. The effect of these compounds on t

APA, Harvard, Vancouver, ISO, and other styles

21

Koshmanova, A. N., and M. L. Maksimov. "Prospects for the Cortexin application." Glavvrač (Chief Medical Officer), no. 7 (July 1, 2022): 21–24. http://dx.doi.org/10.33920/med-03-2207-05.

Full text

Abstract:

Cortexin is a multicomponent preparation containing low-molecular-weight neuropeptides (complex of L-amino- and ribonucleic acids), vitamins and microelements. It belongs to the group of nootropic drugs and contributes to the activation of the higher brain activity, restoration of cognitive functions, reduction of neurological deficits, and the increase in brain resistance to aggressive factors. In addition to Cortexin, nootropics include: piracetam, cerebrolysin, citicoline, mexidol and many others. There are data indicating the high efficiency of Cortexin in the treatment of ischemic strokes

APA, Harvard, Vancouver, ISO, and other styles

22

Tribrat, Natalia, Yulia Knizhnik, Denis Khusainov, et al. "The evaluation of the grape polyphenoles nootropic activity in resveratrol and in the food concentrate “Enoant”." BIO Web of Conferences 40 (2021): 02002. http://dx.doi.org/10.1051/bioconf/20214002002.

Full text

Abstract:

The article is devoted to the comparison of the nootropic activity of the grape polyphenoles in resveratrol and in the food concentrate “Enoant” at doses 20 mg/kg, using the Barnes maze in animals. It was found out that resveratrol and the food concentrate “Enoant” demonstrate the positive nootropic effect in the Barnes maze, which is expressed by the changes in the time spent on searching for a burrow and the number of incorrect definitions of the true burrow.

APA, Harvard, Vancouver, ISO, and other styles

23

Kuprash, Liana, Tetyana Panteleymonova, Nina Sykalo, Irina Labunets, and Vladislav Bezrukov. "Nootropic properties of a new combined cytoprotective agent." Issue 3 2022, no. 3 2022 (August 11, 2022): 92–100. http://dx.doi.org/10.47855/jal9020-2022-3-4.

Full text

Abstract:

Medicinal products of nootropic action, which have a positive effect on neurometabolism and normalize memory and intellectual functions, are an important component of complex pharmacotherapy for various neurological and cerebrovascular diseases. The aim of the work was an experimental study of the nootropic activity of the new combined drug Melarginin, which includes 3-(2,2,2-trimethylhydrazinium) propionate (meldonium), L-arginine, and inosine in a fixed ratio. In experiments on female Balb/c mice, it was established that Melarginin in doses of 250 and 500 mg/kg (per os for 14 days) statistic

APA, Harvard, Vancouver, ISO, and other styles

24

Bhargavan, Divya, Suchetha Kumari, and Deepa B. "EVALUATION OF NOOTROPIC ACTIVITY OF ACHYRANTHES ASPERA LEAVES EXTRACT IN WISTAR RATS." Asian Journal of Pharmaceutical and Clinical Research 11, no. 12 (2018): 218. http://dx.doi.org/10.22159/ajpcr.2018.v11i12.28314.

Full text

Abstract:

Objective: The objective of the study was to evaluate the nootropic activity of hydroalcoholic extract of Achyranthes aspera leaves using elevated plus maze and radial arm maze.Methods: Adult Wistar rats were allotted to three groups; Group 1 served as control, Groups 2 and 3 received 200 mg/kg and 400 mg/kg of AA extract, respectively, orally for 2 weeks after which the extent of improvement of memory was assessed.Results: AA showed nootropic activity in both elevated plus maze and radial arm maze. 200 mg/kg of AA extract showed better improvement in learning and memory compared to 400 mg/kg.

APA, Harvard, Vancouver, ISO, and other styles

25

Mirzaev, Y. R., R. A. Botirov, S. F. Aripova, and I. Zhalalov. "About The Nootropic Properties of Donsumine." Aug-Sep 2023, no. 35 (August 25, 2023): 27–33. http://dx.doi.org/10.55529/jhtd.35.27.33.

Full text

Abstract:

Previous studies of Donsumine showed that Donsumine at doses of 3, 5, 10 mg/kg enhances motor activity (MA), verticalization, and at a dose of 100 mg/kg reduces it by 60%. It was also established that Donsumine at doses of 3 and 30 mg/kg enhances the activation of MA and verticalization caused by phenamine, the increase in MA persists until the end of the experiment, and when canceled it is compared with control mice. When canceled, the activity of experimental and control mice becomes the same. It was also established that Donsumine in the "open field" experiments at doses of 1, 10 and 100 mg

APA, Harvard, Vancouver, ISO, and other styles

26

Warad, VijayanandBasabaraj, Manodeep Chakraborty, Prasana Habbu, et al. "Preparation and screening of Swarnaprashana for nootropic activity." International Journal of Nutrition, Pharmacology, Neurological Diseases 4, no. 3 (2014): 170. http://dx.doi.org/10.4103/2231-0738.132677.

Full text

APA, Harvard, Vancouver, ISO, and other styles

27

Akhundov, R. A., V. A. Zagorevskii, and T. A. Voronina. "Nootropic activity of nicotinamide and its structural analogs." Bulletin of Experimental Biology and Medicine 110, no. 4 (1990): 1365–68. http://dx.doi.org/10.1007/bf00842287.

Full text

APA, Harvard, Vancouver, ISO, and other styles

28

Nasibullina, N. M. "Modern advances in the development of neurotropic drugs." Kazan medical journal 81, no. 2 (2022): 141–43. http://dx.doi.org/10.17816/kazmj96295.

Full text

Abstract:

Among the drugs that prevent the development of mental illness, the consequences of epilepsy and cerebral palsy, the use of neurotropic drugs in various dosage forms (DF) is considered promising and expedient [1, 49, 18]. Over the past 10-15 years, a large number of publications have been accumulated on the achievements in the development of highly active neurotropic drugs, which served as an impetus for the study of their pharmacological activity and mechanism of action. Nevertheless, among specialists involved in the search and development of nootropics, there is no single point of view rega

APA, Harvard, Vancouver, ISO, and other styles

29

A. Nagesh, Bhooshitha, Sneha Desai, Krishna K. Linganna, et al. "MULMINATM REVERSES MEMORY IMPAIRMENT INDUCED BY GABAPENTIN IN PTZ EPILEPTIC MOUSE MODEL AND EXHIBITS SYNERGISTIC ANTIEPILEPTIC ACTIVITY." Indian Drugs 60, no. 05 (2023): 80–88. http://dx.doi.org/10.53879/id.60.05.12969.

Full text

Abstract:

Epilepsy is a neurological condition that causes unprovoked, recurrent seizures and memory impairment is a common side effect of epileptic treatment. The present study was conceptualized to evaluate the protective effect of the nootropic herbal drink MulminaTM against memory impairment induced by Gabapentin in a pentylenetetrazole-induced epileptic mouse model. The antiepileptic and memory impairment activity were found to be significantly (p<0.05) higher in the gabapentin group, whereas the combination of gabapentin + MulminaTM significantly (p<0.05) increased antiepileptic and decrease

APA, Harvard, Vancouver, ISO, and other styles

30

Sumaiyya, Saleem* Sana Begum Tayyaba Mahtab S. Ramya Sri. "EVALUATION OF NOOTROPICACTIVITY OF NEWLY SYNTHESIZED GABA DERIVATIVE IN MICE." Indo American Journal of Pharmaceutical Sciences 05, no. 06 (2018): 5527–46. https://doi.org/10.5281/zenodo.1296989.

Full text

Abstract:

<strong><em>Objective</em></strong><em>: This study was aimed to “Evaluate the Nootropic activity of newly synthesized GABA derivative in Mice”</em> <strong><em>Methodology</em></strong><em>: The activity of the Test drug studied using the Actophotometer test model in swiss albino mice. Learning and memory parameters were evaluated using Open field test. The Test drug was administered in dose of50mg/kg body weight i.p. to the respective groups. Piracetam (200mg/kg,i.p.) was used as astandard nootropic agent.</em> <strong><em>Results</em></strong><em>: It was observed Test drug at a

APA, Harvard, Vancouver, ISO, and other styles

31

Vorontsova, O. N., A. G. Alyaeva, K. N. Koliasnikova, P. Yu Povarnina, T. A. Gudasheva, and V. L. Dorofeev. "Involvement of TRK receptors in the nootropic effect of cycloprolylglycine." Pharmacokinetics and Pharmacodynamics, no. 4 (January 26, 2025): 55–62. https://doi.org/10.37489/2587-7836-2024-4-55-62.

Full text

Abstract:

Background. The neuropeptide cycloprolylglycine (CPG) is an endogenous dipeptide analogue of the nootropic piracetam. It has been experimentally shown that CPG (designed and synthesized at the Federal State Budgetary Scientific Institution «Federal Research Center of Original and Promising Biomedical and Pharmaceutical Technologies») has a spectrum of pharmacological effects characteristic of piracetam. In studies aimed at studying the mechanisms of action of CPG, it was found that glutamate AMPA receptors and neutrophin Trk receptors are involved in the anxiolytic, neuroprotective and antihyp

APA, Harvard, Vancouver, ISO, and other styles

32

Povarnina, P. Yu, S. A. Yarkov, T. A. Gudasheva, M. A. Yarkova, and S. B. Seredenin. "The Novel Dipeptide Translocator Protein Ligand, Referred to As GD-23, Exerts Anxiolytic and Nootropic Activities." Acta Naturae 7, no. 3 (2015): 108–12. http://dx.doi.org/10.32607/20758251-2015-7-3-108-112.

Full text

Abstract:

The translocator protein (TSPO) promotes the translocation of cholesterol to the inner mitochondrial membrane and mediates steroid formation. In this study, we first report on a biological evaluation of the dipeptide GD-23 (N-carbobenzoxy-L tryptophanyl-L isoleucine amide), a structural analogue of Alpidem, the principal TSPO ligand. We show that GD-23 in a dose range of 0.05 to 0.5 mg/kg (i.p.) exhibits anxiolytic activity in the elevated plus maze test and nootropic activity in the object recognition test in scopolamine-induced amnesia in rodents. It was shown that GD-23 did not affect spont

APA, Harvard, Vancouver, ISO, and other styles

33

Tripathi, Amitabh, Bhupendra Chauhan, Vinit K. Sharma, and Alok Mukerjee. "Evaluation of Effective Dose Combination of Modafinil and Caffeine for the Management of Narcolepsy against Scopolamine-Induced Amnesia." International Journal of Pharmaceutical Sciences and Drug Research 15, no. 04 (2023): 528–32. http://dx.doi.org/10.25004/ijpsdr.2023.150417.

Full text

Abstract:

To investigate the effective dose combination of modafinil and caffeine by estimating nootropic activity for the management of narcolepsy. The effective dose combination of modafinil and caffeine was determined by the evaluation of nootropic activity in male albino rats of the wistar strain. Modafinil and caffeine were administered in combination to test group 1, II and III orally, followed by scopolamine to induce amnesia. The dose of modafinil was kept constant at 50 mg/day, while the dose of caffeine was reduced gradually in all the treatment groups. Modafinil alone at a dose of 200 mg/day

APA, Harvard, Vancouver, ISO, and other styles

34

Drozdov, A. L., E. M. Demchenko, A. Ejjyad та O. P. Nerush. "Вплив психотропних лікарських засобів на спонтанну поведінкову актиність білих щурів". Visnyk of Dnipropetrovsk University. Biology, medicine 2, № 1 (2011): 47–53. http://dx.doi.org/10.15421/021108.

Full text

Abstract:

Data obtained showed that using of neuroleptics in conditions of experimental psychosis was accompanied by the decreasing of mobility, investigative behavior and emotionality in experimental animals more than in intact ones. Asopposed to that, the action of atypical antipsychotic drug – sulpiride was characterized by the anxiety decreasing but the mobility increasing. The nootropic agents resulted in increasing of motor and emotional activity. The established pharmacological effects of neuroleptics, antidepressants and nootropic agents may use in clinical practice for treatment optimization of

APA, Harvard, Vancouver, ISO, and other styles

35

Turdybekov, K. M., O. A. Nurkenov, T. M. Seilkhanov, S. D. Fazylov, Ya G. Turdybekova, and A. S. Kudusov. "SYNTHESIS, SPATIAL STRUCTURE, AND NOOTROPIC ACTIVITY OF N-CYANOMETHYLANABASINE." Journal of Structural Chemistry 63, no. 6 (2022): 944–50. http://dx.doi.org/10.1134/s0022476622060117.

Full text

APA, Harvard, Vancouver, ISO, and other styles

36

Mushtaq, Aamir, Rukhsana Anwar, Umar Farooq Gohar, et al. "Biomolecular Evaluation of Lavandula stoechas L. for Nootropic Activity." Plants 10, no. 6 (2021): 1259. http://dx.doi.org/10.3390/plants10061259.

Full text

Abstract:

Lavandula Stoechas L. is widely known for its pharmacological properties. This study was performed to identify its biomolecules, which are responsible for enhancement of memory. L. stoechas aqueous extract was first purified by liquid column chromatography. The purified fractions were analyzed for in vitro anti-cholinesterase activity. The fraction that produced the best anti-cholinesterase activity was named an active fraction of L. stoechas (AfL.s). This was then subjected to GC–MS for identifications of biomolecules present in it. GC–MS indicated the presence of phenethylamine and α-tocophe

APA, Harvard, Vancouver, ISO, and other styles

37

Gudasheva, T. A., N. I. Vasilevich, R. U. Ostrovskaya, et al. "Synthesis and nootropic activity of pyrrolidino[1,2-a]diazacycloalkanes." Pharmaceutical Chemistry Journal 30, no. 9 (1996): 562–67. http://dx.doi.org/10.1007/bf02219346.

Full text

APA, Harvard, Vancouver, ISO, and other styles

38

RAKHMANKULOVA, I., and G. KUZNETSOVA. "Correlation between nootropic activity and adaptive stability of drugs." Pharmacological Research 31 (1995): 264. http://dx.doi.org/10.1016/1043-6618(95)87316-3.

Full text

APA, Harvard, Vancouver, ISO, and other styles

39

Gudasheva, T. A., R. U. Ostrovskaya, F. V. Maksimova, et al. "Proline-based topologic pyracetam analogs and their nootropic activity." Pharmaceutical Chemistry Journal 23, no. 3 (1989): 203–8. http://dx.doi.org/10.1007/bf00831694.

Full text

APA, Harvard, Vancouver, ISO, and other styles

40

M., Naveen Kumar, and Virender Kolagani. "EVALUATION OF NOOTROPIC ACTIVITY OF CARICA PAPAYA IN MICE." Biolife 2, no. 3 (2022): 721–30. https://doi.org/10.5281/zenodo.7219751.

Full text

Abstract:

<strong>ABSTRACT</strong> Alzheimer’s disease is a progressive neurodegenerative disorder primarily manifesting as a loss of memory, senile dementia, and intraneuronal neurofibrillary tangle formation. <em>C. papaya</em> has a very long history of medicinal use in Chinese and Indian herbal traditions. The objective of this study is to evaluate the nootropic activity of Carica papaya by using animal model mice. The dried seeds of papaya fruits were used for the extraction by cold maceration method using ethanol as solvent. Preliminary Phytochemical study was performed. Estimation of anti-

APA, Harvard, Vancouver, ISO, and other styles

41

Vishal, Jadhav* Priyadarshani Ladhave Rupali Rathod. "Memory Enhancing Medicine: Do they really work?" International Journal of Pharmaceutical Sciences 3, no. 2 (2025): 17–23. https://doi.org/10.5281/zenodo.14785481.

Full text

Abstract:

Dementia is a syndrome usually occurs in Alzheimers (AD) disease and vascular dementia (VD) due to disease in brain drugs considers cognitive enhancers includes dietary product and supplimentracetams, stimulant dopaminergics, cholinergics, GABA blockers, glutamate activator and harmones etc. in recent years research on medicinal plants have been studied for nootropic activity memory gives an individual the capability to learn and adpt from previous experience and the power of recalling the previous learn facts, skill and habits. Some the herbs that help in enhancing on memory are bacopa, monni

APA, Harvard, Vancouver, ISO, and other styles

42

Katti, Suvarna A. "Design, Synthesis and In Silico Evaluation of 1,3,4-Oxadiazole Derivatives for Their Nootropic Activity." Chettinad Health City Medical Journal 13, no. 04 (2024): 43–54. https://doi.org/10.24321/2278.2044.202458.

Full text

APA, Harvard, Vancouver, ISO, and other styles

43

Bharti, Raj Kumar Singh, Amit Kumar, Munna Singh, Ankita Tripathi, and Priya Pandey. "BEHAVIORAL AND BIOCHEMICAL INVESTIGATION OF AMARANTHUS SPINOSUS FOR ANTISTRESS AND NOOTROPIC ACTIVITY ON RATS." Journal of Biological & Scientific Opinion 10, no. 3 (2022): 30–37. http://dx.doi.org/10.7897/2321-6328.103156.

Full text

Abstract:

There is a number of Synthetic (allopathic) drugs which are used in the treatment of mental disorders, they are helpful but synthetic drugs also have lots of side effects with monetary problem. The Ayurveda has a long tradition of treating mental disorders. Herbal drugs are playing a significant role in the health care agendas worldwide, mostly due to the general faith that they are without any side effects, besides being contemptible and locally available. Recently there is a recovery of an interest in herbal medicines for the management of different aliments including CNS disorders. Experime

APA, Harvard, Vancouver, ISO, and other styles

44

Lievykh, А.E., N.S. Bondarenko, S.N. Dronov, V.I. Mamchur, I.V. Tverdokhlib, and V.I. Zhyliuk. "Experimental substantiation of the expediency of the combined use of piracetam and metformin for pharmacological correction of cognitive disorders in conditions of prolonged hyperglycemia." Medicni perspektivi 25, no. 3 (2020): 30–39. https://doi.org/10.26641/2307-0404.2020.3.214647.

Full text

Abstract:

Chronic hyperglycemia, insulin resistance, endothelial dysfunction, and disturbance of the integrity of the blood-brain barrier are considered as strategically important links in the development of cognitive deficits in diabetic encephalopathy. Taking this into account, one of the modern trends in the optimization of the treatment of cognitive impairments induced by prolonged hyperglycemia is the co-administration of agents with antihyperglycemic and nootropic activity, in particular, metformin with piracetam. It has been shown that under conditions of experimental alloxan-induced hyperglycemi

APA, Harvard, Vancouver, ISO, and other styles

45

Shilova, I. V. "Research biologically active substances Atragene speciose Weinm." Bulletin of Siberian Medicine 1, no. 2 (2002): 55–59. http://dx.doi.org/10.20538/1682-0363-2002-2-55-59.

Full text

Abstract:

From the overground part of Atragene speciosa Weinm. family Ranunculaceae, we obtained a fraction possessing a marked nootropic effect from which 3,4-dihydroxyphenylethanol-2, its 2-O-β-D-glucopyranoside, and a sum of glycosides of dihydroxybutane acid were isolated. In addition to the foregoing substances, in the pharmacologically active fraction we revealed the presence of triterpene glycosides (whose sapogenins are hederagenine and oleanolic acid), aminoacids and microelements. For the frist time the obtained data about the biologically active substances and their pharmacological activity g

APA, Harvard, Vancouver, ISO, and other styles

46

K.V., Anil Kumar, Vimala N., Rama T., and Satyanarayana Sreemanthula. "ATTENUATION OF STRESS INDUCED URINARY BIOCHEMICAL CHANGES AND SCOPOLAMINE-INDUCED MEMORY LOSS BY HYDROALCOHOLIC SEED EXTRACT OF CELASTRUS PANICULATUS WILLD. IN RAT MODEL." INDIAN DRUGS 58, no. 07 (2021): 38–45. http://dx.doi.org/10.53879/id.58.07.12639.

Full text

Abstract:

Ayurveda uses seeds of Celastrus paniculatus to treat various stress related disorders. In the present investigation, the hydroalcoholic seed extract of C. paniculatus was evaluated for anti-stress activity by forced swim stress model. Vanillylmandelic acid and ascorbic acid were selected as non-invasive biomarkers to assess the anti-stress activity. Nootropic activity in rats was evaluated by conditioned avoidance response using Cook’s pole climbing apparatus, the antioxidant potential was determined based on the ability of the extract to scavenge hydroxyl radicals. Pretreatment with the extr

APA, Harvard, Vancouver, ISO, and other styles

47

Rasal, Vijaykumar P., Pawan Kharade, and Rajashaker S. Chavan. "Screening of Black spruce oil for nootropic activity in rats." Asian Journal of Pharmacy and Pharmacology 5, no. 6 (2019): 1237–43. http://dx.doi.org/10.31024/ajpp.2019.5.6.23.

Full text

APA, Harvard, Vancouver, ISO, and other styles

48

Nirwane, AbhijitM, PurnimaV Gupta, JiteshH Shet, and SandeepB Patil. "Anxiolytic and nootropic activity of Vetiveria zizanioides roots in mice." Journal of Ayurveda and Integrative Medicine 6, no. 3 (2015): 158. http://dx.doi.org/10.4103/0975-9476.146548.

Full text

APA, Harvard, Vancouver, ISO, and other styles

49

Une, H. D., V. P. Sarveiya, S. C. Pal, V. S. Kasture, and S. B. Kasture. "Nootropic and anxiolytic activity of saponins of Albizzia lebbeck leaves." Pharmacology Biochemistry and Behavior 69, no. 3-4 (2001): 439–44. http://dx.doi.org/10.1016/s0091-3057(01)00516-0.

Full text

APA, Harvard, Vancouver, ISO, and other styles

50

Mustafin, R. N., I. V. Shilova, N. I. Suslov, N. V. Kuvacheva, and V. P. Amelchenko. "Nootropic Activity of Extracts from Wild and Cultivated Alfredia Cernua." Bulletin of Experimental Biology and Medicine 150, no. 3 (2011): 333–35. http://dx.doi.org/10.1007/s10517-011-1135-0.

Full text

APA, Harvard, Vancouver, ISO, and other styles

We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!