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Dissertations / Theses on the topic 'Nootropics'

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1

Sanku, Rajesh Kishore kumar. "DEVELOPMENT AND BIOLOGICAL EVALUATION OF CARBONIC ANHYDRASE MODULATORS AS POTENTIAL NOOTROPICS AND ANTICANCER AGENTS." Diss., Temple University Libraries, 2018. http://cdm16002.contentdm.oclc.org/cdm/ref/collection/p245801coll10/id/487142.

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Pharmaceutical Sciences<br>Ph.D.<br>Cancer is the second most common cause of death in the world. One of the objectives of this thesis is to biologically evaluate a series of anti-cancer polymeric aromatic/heterocyclic bis-sulfonamides and pyridinium sulfonamides which were synthesized from three established aminosulfonamide carbonic anhydrase (CA, EC 4.2.1.1) inhibitor pharmacophores. Testing of these novel inhibitors and their precursors against a panel of membrane-bound CA isoforms, including tumor-overexpressed CA IX and XII and cytosolic isozymes, identified nanomolar-potent inhibitors ag
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2

Prevost, Dominique. "Le Piracetam, chef de file des nootropes." Bordeaux 2, 1991. http://www.theses.fr/1991BOR2P065.

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3

MONTAVONT, DIDIER VERONIQUE. "Recherches recentes dans le domaine des nootropes." Strasbourg 1, 1993. http://www.theses.fr/1993STR15031.

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4

Mohamed, Ahmed Dahir. "The neuroscience & ethics of cognitive enhancement in healthy individuals." Thesis, University of Cambridge, 2013. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.607755.

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5

McCormick, Sean Eli. "Transcendence: An Ethical Analysis of Enhancement Technologies." Cleveland State University / OhioLINK, 2016. http://rave.ohiolink.edu/etdc/view?acc_num=csu1464233924.

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6

Barnes, J. M. "Neurochemical assessments of the actions of novel agents having nootropic and anxiolytic potential." Thesis, University of Bradford, 1989. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.234701.

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7

Nanas, Nikolaos. "Towards Nootropia : a non-linear approach to adaptive document filtering." Thesis, Open University, 2003. http://oro.open.ac.uk/54624/.

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In recent years, it has become increasingly difficult for users to find relevant information within the accessible glut. Research in Information Filtering (IF) tackles this problem through a tailored representation of the user interests, a user profile. Traditionally, IF inherits techniques from the related and more well established domains of Information Retrieval and Text Categorisation. These include, linear profile representations that exclude term dependencies and may only effectively represent a single topic of interest, and linear learning algorithms that achieve a steady profile adapta
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8

RATTO, DANIELA. "Nootropic and antioxidant metabolites of Hericium erinaceus enhanced healthy aging in a preclinical model and improved mood disorders in patients." Doctoral thesis, Università degli studi di Pavia, 2022. http://hdl.handle.net/11571/1452903.

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9

Hamilton, Mindy. "A Critical Discourse Analysis of Cognitive Enhancement Advertising: The Contemporary Mind as a Commodity." University of Cincinnati / OhioLINK, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1535468783036117.

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10

Tedelind, Jonas. "Nootropikum : Piracetam som kognitionsförbättrare." Thesis, Umeå universitet, Farmakologi, 2017. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-137152.

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11

Fisher, Kim Noël. "Behavioural and physiological effects of two aniracetam analogues." Thesis, McGill University, 1994. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=22585.

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The behavioural and electrophysiological consequences of two newly developed aniracetam analogues were investigated in male Long-Evans rats. Results indicate that an intraperitoneal (i.p.) injection of LD38.2 significantly improved retention in a two odour olfactory discrimination task. However, three different dosages of LN1 did not facilitate memory in the task. In rats with chronically implanted electrodes, both compounds rapidly crossed the blood brain barrier (BBB) after an i.p. injection and influenced several parameters of the field excitatory postsynaptic potential (EPSP) in the CA1 an
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12

Krishnan, Vinu. "Design and Synthesis of Nanoparticle “PAINT-BRUSH” Like Multi-Hydroxyl Capped Poly(Ethylene Glycol) Conjugates for Cancer Nanotherapy." Akron, OH : University of Akron, 2008. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=akron1217677351.

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Thesis (M.S.)--University of Akron, Dept. of Biomedical Engineering, 2008.<br>"August, 2008." Title from electronic thesis title page (viewed 12/9/2009) Advisor, Stephanie T. Lopina; Committee members, Amy Milsted, Daniel B. Sheffer, Daniel Ely; Department Chair, Daniel B. Sheffer; Dean of the College, George K. Haritos; Dean of the Graduate School, George R. Newkome. Includes bibliographical references.
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13

Cruz, Margarida Inês Delgado de Melo. "Use of nootropics among Portuguese Medical Students." Master's thesis, 2018. https://hdl.handle.net/10216/112434.

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Cruz, Margarida Inês Delgado de Melo. "Use of nootropics among Portuguese Medical Students." Dissertação, 2018. https://hdl.handle.net/10216/112434.

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15

Adams, BLM. "Monitoring the internet for nootropic substances available to Australian consumers." Thesis, 2019. https://eprints.utas.edu.au/31406/1/Adams_whole_thesis.pdf.

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There is a historical interest in improving cognitive performance for individuals in fields such as academia. Nootropics, also known as smart drugs, are increasingly being used by individuals to obtain desirable cognitive benefits. Research has focused on investigating the potential benefits of nootropics through animal studies, however there is limited knowledge regarding the potential adverse side effects of these substances in humans. An online, active community of nootropic consumers have provided consumer experiences and advice for new consumers, to aid in the navigation of the vast nootr
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16

MARTINO, MARIA VITTORIA. "Progettazione, sintesi e valutazione farmacologica preliminare di ligandi e modulatori dei recettori colinergici centrali." Doctoral thesis, 2015. http://hdl.handle.net/2158/986407.

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Il lavoro effettuato in questi 3 anni di dottorato è stato svolto nell’ambito del progetto PRIN 2009, basato sulla ricerca di sostanze in grado di modulare, direttamente o indirettamente, i recettori colinergici a livello centrale; lo scopo è quello di sviluppare molecole in grado di migliorare i processi cognitivi, quindi utilizzabili nel trattamento di patologie caratterizzate da deficit cognitivo come morbo Alzheimer, schizofrenia, mild cognitive impairment. Le linee di ricerca su cui si è sviluppato tale progetto andavano in 3 direzioni: - Ricerca di ligandi muscarinici selettivi; - Ricerc
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17

Garringer, Eva Marie. "Modlation of AMPA receptor desensitization by nootropic drugs and endogenous proteins." 2005. http://digital.library.okstate.edu/etd/umi-okstate-1307.pdf.

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18

Seif, Taban. "D-cycloserine enhances postsynaptic excitability in vitro : novel and conserved nootropic mechanism /." 2007. http://proquest.umi.com/pqdweb?did=1445034881&sid=7&Fmt=2&clientId=10361&RQT=309&VName=PQD.

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19

Hofmeister, Erik Henry. "Over-the-counter stimulant, depressant, and nootropic use in veterinary medical students." 2008. http://purl.galileo.usg.edu/uga%5Fetd/hofmeister%5Ferik%5Fh%5F200812%5Fma.

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20

Jeffrey, Scott C. "Synthetic studies n bioactive natural products. Part I, An approach towards the nootrophic agent huperzine A. Part II, Synthesis of the tricarbonyl subunit of rapamycin." Thesis, 1996. http://hdl.handle.net/1957/34483.

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21

Kim, Jungchul. "Natural product synthesis via cyclobutanes : part I, Asymmetric synthesis of (+)-byssochlamic acid, part II, An approach to the nootropic agent huperzine A." Thesis, 2000. http://hdl.handle.net/1957/32732.

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PART I. Asymmetric syntheses of both natural (+)- and nonnatural (-)- byssochlamic acid via a [2+2] photoaddition-cycloreversion strategy are described. X-ray crystallographic analysis of the cyclohexylamine salt 99 showed that the structure of the monomethyl ester 100 from esterase hydrolysis of 44 was originally misassigned as 56. The enantiomeric relationship of the two diolides 106 and 70 permitted syntheses of nonnatural byssochlamic acid (-)-3 and natural byssochiamic acid (+)-3 from enantiopure alcohol (+)-64 and from its enantiomer (-)-110, respectively. Through the use of (��)-103 to
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22

Millington, Chris. "The effects of chronic neuroinflammation on cognition and behaviour in the GFAP-IL6 transgenic mouse and an investigation of the nootropic AGE inhibitor Tenilsetam." Thesis, 2018. http://hdl.handle.net/1959.7/uws:59607.

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Neurodegenerative and neurological disorders are incurable diseases that represent an enormous burden both financially and in terms of human suffering. Chronic neuroinflammation, demonstrated by the activation of microglia and astrocytes and the release of reactive oxygen species and pro-inflammatory cytokines, has been identified as one of the major factors in the pathogenesis of several neurological, neurodegenerative and psychiatric diseases. Understanding the underlying neuroinflammation and developing therapies that can target the inflammatory and degenerative processes is a key strategy
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