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Dissertations / Theses on the topic 'Noradrenaline'

Author: Grafiati

Published: 4 June 2021

Last updated: 25 July 2025

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1

Smith, Nigel. "Plasma protein binding of noradrenaline." Thesis, University of Nottingham, 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.252951.

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2

Scriven, Anthony James Ivor. "Plasma noradrenaline and cardiovascular sympathetic activity." Thesis, Imperial College London, 1990. http://hdl.handle.net/10044/1/46541.

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3

Haywood, S. A. "GnRH network : noradrenaline and sex steroids." Thesis, University of Cambridge, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.603906.

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The first studies in this thesis use <I>in situ</I> hybridisation to investigate if temporal changes occur in cellular GnRH gene expression during the preovulatory phase of the oestrous cycle and further investigation gene expression in other neurotransmitter systems in the GnRH network within the preoptic area and the brainstem. It is evident from these studies that, during the oestrous cycle, transcriptional changes within GnRH, enkphalin, nitric oxide synthase and noradrenaline containing neural populations, in the preoptic area and brainstem respectively, are small, and are perhaps not per

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4

Field, Brent A. "The effects of noradrenaline on cortical signal processing /." view abstract or download file of text, 2000. http://wwwlib.umi.com/cr/uoregon/fullcit?p9978587.

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Thesis (Ph. D.)--University of Oregon, 2000.<br>Typescript. Includes vita and abstract. Includes bibliographical references (leaves 140-159). Also available for download via the World Wide Web; free to University of Oregon users.

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5

Kelly, Christopher Brendan. "Noradrenergic function in anxiety and depressive states." Thesis, Queen's University Belfast, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.261770.

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6

Roberts, Veronica J. "Corticosterone modulation of noradrenaline stimulated cyclic AMP formation in hippocampus." Thesis, University of Ottawa (Canada), 1985. http://hdl.handle.net/10393/4949.

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7

Brice, Carolyn F. "Caffeine : consumption, behavioural effects and the role of central noradrenaline." Thesis, University of Bristol, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.302061.

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8

Popovik, Elvira. "The role of noradrenaline in the development of rat neocortex." Thesis, University of Bristol, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.289632.

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9

DONG, WEN-XIN. "Metabolisme pre-synaptique peripherique de la noradrenaline chez le rat." Paris 6, 1997. http://www.theses.fr/1997PA066067.

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Nous avons etudie le metabolisme pre-synaptique de la noradrenaline (na) chez l'animal entier ; cette voie metabolique etant la voie la plus importante pour la na synaptique. Un dosage radio-enzymatique, approprie pour mesurer les concentrations plasmatiques des derives desamines de la na (3,4-dihydroxyphenyl glycol : dhpg et 3,4-dihydroxymandelique acide : doma) a ete developpe et valide au plan physiologique. Une reduction de l'activite sympathique par la clonidine ou la guanethidine provoque une baisse de la na mais aussi du dhpg ; la reponse du doma est moins claire. Dans une deuxieme etap

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10

MAIGNAN, EMMANUELLE. "Systeme sympathique : la cinetique de la noradrenaline chez le rat." Paris 6, 2001. http://www.theses.fr/2001PA066331.

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L'objectif de ce travail a ete d'etudier la physiologie du systeme sympathique chez le rat par la technique de la dilution isotopique (di). Nous avons mesure la cinetique de la noradrenaline (na), definie par son trop plein synaptique (tps) et sa clairance metabolique (cm). Nous montrons que l'anesthesie provoque des alterations majeures et heterogenes de la cinetique de la na. Nous avons d'abord retenu que l'etat experimental qui s'imposait etait le rat conscient, non restreint. Dans ce contexte, son tps est environ 10 fois plus eleve que celui de l'homme, suggerant une activite sympathique b

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11

Kennett, Alexandra. "Nicotinic acetylcholine receptor modulation of noradrenaline release in the rodent brain." Thesis, University of Bath, 2011. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.557794.

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Cognitive function in the brain is controlled by neurotransmitters whose release is tightly controlled. When normal levels are perturbed deficits in function can be observed both in humans and in animal models. The cholinergic system, acting via muscarinic or nicotinic receptors, modulates neurotransmitter release. The aim of this thesis was to investigate the identity of the nicotinic acetylcholine receptor (nAChR) subtypes involved in modulating noradrenaline (NA) release, in rodent frontal cortex (FC) and hippocampus (HC). Comparisons were made both in vitro and in vivo using pharmacologica

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12

Abebe, Worku. "Noradrenaline-induced vascular contractility and phosphoinositide metabolism in streptozotocin-diabetic rats." Thesis, University of British Columbia, 1990. http://hdl.handle.net/2429/30549.

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Alterations in the reactivity of blood vessels to neurotransmitters and circulating hormones have been suggested to cause, or contribute to, some of the cardiovascular complications associated with diabetes mellitus. Previous studies have demonstrated that aortae and mesenteric arteries from male rats with streptozotocin (STZ)-induced diabetes of 12 weeks duration are more responsive to the contractile effects of noradrenaline (NA). The increased responsiveness of the diabetic arteries to NA has been reported to result from stimulation of α₁-adrenoceptors. Contraction of vascular smooth muscle

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13

Wang, Yushan. "Release of glutamate, noradrenaline and adenosine from rat parietal cortical slices." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2000. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape4/PQDD_0009/NQ60669.pdf.

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14

McCance, Alastai J. "Systemic and cardiac noradrenaline kinetics in ischaemic heart disease in man." Thesis, University of Oxford, 1989. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.235891.

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15

Siyamak, Ahmed Y. "Studies of the effects of nutritional factors on noradrenaline-induced thermogenesis." Thesis, University of Nottingham, 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.291275.

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16

Tse, Wai Shing. "The role of noradrenaline in different aspects of human social behaviour." Thesis, University of Birmingham, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.272325.

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17

Dunk, Christopher Robert. "The uptake of noradrenaline by human red blood cells and ghosts." Thesis, University of Leicester, 1989. http://hdl.handle.net/2381/34331.

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A study has been made of the transport of noradrenaline into human red cells and resealed ghosts. In cells uptake appeared to obey the kinetics of simple diffusion, whilst in metabolically inert ghosts, uptake was identified as a low affinity high capacity saturable transport mechanism. Uptake was markedly temperature sensitive but not dependent upon cellular metabolism, consistent mth facilitated diffusion rather than active transport of noradrenaline. Non-competitive inhibition of uptake was achieved by a variety of structurally related compounds when present at either the inner or outer mem

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18

Singh, Lakhbir. "Modulation of a 5-hydroxytryptamine-related behaviour by noradrenaline and gaba." Thesis, Aston University, 1985. http://publications.aston.ac.uk/12471/.

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19

gov, Clearys@ninds nih, and Susannah Cleary. "From chromaffin cells to Phaeochromocytoma : insight into the sympathoadrenal cell lineage." Murdoch University, 2007. http://wwwlib.murdoch.edu.au/adt/browse/view/adt-MU20080526.105525.

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Chromaffin cells are a modified post-ganglionic sympathetic neuron, which synthesise and secrete catecholamines. The neoplastic transformation of chromaffin cells is demonstrated by the tumour phaeochromocytoma, a functional tumour that recapitulates the normal role of chromaffin cells by synthesising, storing and releasing excess catecholamines. Within this thesis we have explored several aspects of chromaffin cell and phaeochromocytoma tumour biology, including the specific expression of key sympathoadrenal markers such as the noradrenaline transporter (NAT), neuropeptide Y (NPY) and chromog

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20

Powers, Jennifer Lynn. "Cellular and enzymatic studies with novel adrenergic analogs and effectors." Diss., Georgia Institute of Technology, 1993. http://hdl.handle.net/1853/30262.

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21

Mctavish, Sarah F. B. "The use of tyrosine depletion to evaluate central catecholamine function in animals and man." Thesis, University of Oxford, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.365879.

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22

Phillips, Marc Antony. "An investigation of monoaminergic mechanisms in the regulation of pupil size and the acoustic startle reflex in man." Thesis, University of Nottingham, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.324546.

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23

Link, Jeanne Meyers. "Mixed-mode chromatographic separation and whole column radiation detection to improve sensitivity in radiometabolite analysis : application to (Carbon-11)-meta-hydroxyephedrine in plasma /." Thesis, Connect to this title online; UW restricted, 1998. http://hdl.handle.net/1773/8578.

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24

Bawa, Samiti. "Human platelets : studies on uptake and release of noradrenaline associated with serotonin." Thesis, King's College London (University of London), 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.428700.

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25

Paeger, Lars [Verfasser], and Peter [Akademischer Betreuer] Kloppenburg. "The Role of Noradrenaline in Energy Homeostasis / Lars Paeger. Gutachter: Peter Kloppenburg." Köln : Universitäts- und Stadtbibliothek Köln, 2013. http://d-nb.info/1052993265/34.

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26

Sánchez, Soto Marta. "Noncanonical Neurotransmitter Activation of Catecholamine Receptors." Doctoral thesis, Universitat de Barcelona, 2017. http://hdl.handle.net/10803/400298.

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From the D2‐like receptors (D2,D3, D4), only D4 receptor (D4R) has been described as “promiscuous” since it can be activated both by dopamine (DA) and norepinephrine (NE) and function as a noradrenergic receptor in the brain. However, there is no evidence for the other D2‐like receptors. In addition, D4R has a large number of polymorphisms, one of the variants, D4.7, has been associated with several neuropsychiatric disorders. The first aim of this thesis was to study the possible activation of D2‐like recptors (including the three main D4 variants, D2 short, D2 long and D3) by radiolab

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27

Pedrini, Denise Leda. "Avaliação da adrenalina, noradrenalina e cortisol sob a formação do biofilme, produção de ácido e expressão de fatores de virulência pelo Streptococcus mutans." Universidade de Taubaté, 2012. http://www.bdtd.unitau.br/tedesimplificado/tde_busca/arquivo.php?codArquivo=568.

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Avaliar o efeito in vitro da adrenalina, noradrenalina e cortisol sobre a formação do biofilme, produção de ácido e expressão de fatores de virulência por S. mutans. Método: Para a formação do biofilme foi realizada uma monocultura de S. mutans (UA159) em discos de hidroxiapatita (HA) associados à adrenalina, noradrenalina e cortisol por cinco dias. Após esse período, foi realizada a contagem bacteriana (ufc/ml) para cada grupo experimental. A avaliação da queda do pH (produção de ácidos) foi realizada a cada 12 horas até o final do experimento (cinco dias). Para a avaliação da expressão de fa

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28

Santos, Luiz Marcelo Oliveira. "Mecanismos adrenérgicos no núcleo retrotrapezóide no controle respiratório." Universidade de São Paulo, 2015. http://www.teses.usp.br/teses/disponiveis/42/42136/tde-24022016-153800/.

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O núcleo retrotrapezóide (RTN) é uma região bulbar envolvida na respiração. Estudos prévios mostraram a presença de varicosidades catecolaminérgicas na região do RTN. O objetivo deste estudo foi investigar a fonte de catecolaminas e os efeitos promovidos pela ativação dos receptores adrenérgicos no RTN. Uma densa projeção neuronal do grupamento A7 para o RTN foi revelada usando o traçador retrógrado Fluorogold. Foi registrada a atividade eletromiográfica do diafragma (DiaEMG) e do abdominal (AbdEMG) de ratos Wistar anestesiados. A injeção de noradrenalina promoveu uma inibição da DiaEMG, sem a

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29

Bergen, Hugo Theodore. "The role of norepinephrine in the neuroendocrine regulation of luteinizing hormone release in the rat." Thesis, University of British Columbia, 1988. http://hdl.handle.net/2429/28623.

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An excitatory role for norepinephrine (NE) in the regulation of luteinizing hormone (LH) release was first suggested when it was demonstrated that noradrenergic receptor antagonists were able to block ovulation. More recently it has been proposed that NE has both an excitatory role and an inhibitory role in the neuroendocrine regulation of LH release. The excitatory effects may be mediated by alpha-adrenergic receptors and the inhibitory effects may be mediated via beta-adrenergic receptors. These experiments were performed to better understand the role of NE, the receptor type through which N

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30

Evans, Richard James. "Neuronal control mesenteric arteries." Thesis, University of Oxford, 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.279879.

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31

Houghton, Andrea Karen. "Peptide and monoamine modulation of a withdrawal reflex in the rabbit." Thesis, University of Nottingham, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.294717.

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32

Burton, Claire Louise. "Norepinephrine, iron and Escherichia coli." Thesis, University of Nottingham, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.342475.

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33

VIGIER, THIERRY. "Comparaison de l'adrenaline et de la noradrenaline dans le traitement du choc septique post-operatoire." Nantes, 1993. http://www.theses.fr/1993NANT248M.

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34

Wehrwein, Erica Ariece-Dorothy. "Norepinephrine transporter in the autonomic innervation of the heart and its role in hypertension." Diss., Connect to online resource - MSU authorized users, 2008.

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35

Sirivelu-Prabhakar, Madhu. "Immune stress and reproduction insights into the role of norepinephrine and gaba /." Diss., Connect to online resource - MSU authorized users, 2008.

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Thesis (Ph. D.)--Michigan State University. Dept. of Comparative Medicine and Integrative Biology, 2008.<br>Title from PDF t.p. (viewed July 31, 2009). Includes bibliographical references (p. 165-198). Also issued in print.

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36

Mahmood, Samira Rashid. "Vascular calcium adenosine triphosphatase as a site of noradrenaline and hypotensive drug action." Thesis, Heriot-Watt University, 1985. http://hdl.handle.net/10399/1626.

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37

Hughes, Zoe Alexandra. "Modulation of extracellular noradrenaline in rate cortex by selective serotonin reuptake inhibitors (SSRIs)." Thesis, University College London (University of London), 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.300168.

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38

Clark, Andrew J. M. "On the action of noradrenaline microinjected into the paraventricular nucleus of rat hypothalamus." Thesis, University of St Andrews, 1990. http://hdl.handle.net/10023/14704.

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The microinjection of noradrenaline (NA) into the hypothalamic paraventricular nucleus (PVN) of the rat results in feeding. This response was shown; contrary to previous reports; to be mediated through both a-1 and a-2 NA receptors. Selective blockade of these two receptor sub-types, in conjunction with re-uptake blockade was used to examine the individual contributions of each receptor type to the whole response. It is suggested that the previously reported a-2 receptor specificity of the response to microinjected NA is a result of the location of these receptors. The post-synaptic a-1 recept

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39

Airo, Juha. "Role of cerebral dopamine and noradrenaline in locomotor sensitization to morphine in mice." Helsinki : University of Helsinki, 1999. http://ethesis.helsinki.fi/julkaisut/mat/farma/vk/airio/.

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40

Moreira, Marilia Francisco. "Sensibilidade adrenergica de atrios direitos isolados de ratos normo ou hiperlipidemicos sedentarios ou submetidos a natação." [s.n.], 2005. http://repositorio.unicamp.br/jspui/handle/REPOSIP/314100.

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Orientador: Dora Maria Grassi-Kassisse<br>Dissertação (mestrado) - Universidade Estadual de Campinas, Instituto de Biologia<br>Made available in DSpace on 2018-08-07T08:09:26Z (GMT). No. of bitstreams: 1 Moreira_MariliaFrancisco_M.pdf: 1378785 bytes, checksum: dcaf29a0a3f00f96318d03ee2362989c (MD5) Previous issue date: 2005<br>Resumo: Lipídios provenientes da dieta têm um importante efeito no sistema de sinalização transmembrana presente nas células cardíacas. Um vez ingeridos em excesso ocorre aumento no conteúdo de colesterol na membrana da célula cardíaca o qual afeta a atividade da adeli

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41

Lima, Ronald de Albuquerque. "Comparação dos efeitos microcirculatórios da vasopressina e da noradrenalina associadas à reposição volêmica durante o choque hemorrágico. Estudo experimental em hamster." Universidade do Estado do Rio de Janeiro, 2009. http://www.bdtd.uerj.br/tde_busca/arquivo.php?codArquivo=1030.

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Objetivos: Este trabalho teve como objetivos avaliar in vivo os efeitos microcirculatórios e a sobrevida de animais submetidos ao choque hemorrágico tratados com vasopressina e noradrenalina associadas à reposição volêmica com solução de NaCl 0,9% . Desenho do estudo: Estudo prospectivo, randomizado, controlado, intervencionista em modelo animal. Materiais e métodos: Utilizou-se hamsters machos do tipo sírio dourado, com idade entre 6 e 8 semanas e massa corporal entre 60 e 80 gramas. Os animais foram anestesiados para colocação de uma câmara dorsal. Após 5 a 7 dias, foram re-anestesiados para

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42

Birch, P. J. "The role of presynaptic receptors in the regulation of noradrenaline synthesis in rat hippocampus." Thesis, University of Oxford, 1985. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.370237.

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43

Mason, Kathryn. "Modulation of central noradrenaline efflux by pharmacological and novel environmental stimuli : a microdialysis study." Thesis, University College London (University of London), 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.264181.

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44

Crawford, Andrew Raymond. "Iodoreboxetine : the development of a novel SPECT brain imaging tracer for the noradrenaline transporter." Thesis, University of Glasgow, 2013. http://theses.gla.ac.uk/4226/.

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The noradrenaline system is extensively innervated throughout the brain, implicated in the aetiology of a wide range of psychiatric conditions, and the pharmacological modulation of the noradrenaline system has had a positive influence upon the alleviation of symptoms for those suffering psychiatric or neurological disease. Clinical imaging of the brain with technologies such as Single Photon Emission Computed Tomography (SPECT) can provide clinicians and researchers with valuable information for elucidating disease aetiology, monitoring patient condition, and also confirming the mechanism of

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45

CANDITO, VALLAURI MIRANDE. "Etude circadienne de substances neuro-hormonales circulantes dans la depression : noradrenaline, tryptophane, serotonine, cortisol." Aix-Marseille 2, 1989. http://www.theses.fr/1989AIX22966.

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46

Homar, Ruano Patricia C. "Oligomerización de receptores α₁ᴀ adrenérgicos y receptores dopaminérgicos en el SNC: implicación en la modulación de la atención". Doctoral thesis, Universitat de Barcelona, 2020. http://hdl.handle.net/10803/668694.

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La atención es el proceso cognitivo básico que nos otorga la capacidad de seleccionar aquella información interna o externa que va a ser relevante para la toma de decisiones y el control del comportamiento. Múltiples regiones cerebrales interconectadas entre ellas forman una compleja red de circuitos neuronales capaces de activar y modular diversas funciones cognitivas, como la atención. Concretamente, la corteza prefrontal (PFC) es un punto neurálgico de estos circuitos que, a través de distintas regiones funcionales, orquesta prácticamente todos los aspectos del comportamiento y la cognición

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47

Carpes, Pâmela Billig Mello. "Participação da via NTS-PGI-LC-hipocampo (núcleo do trato solitário- núcleo paragigantocelular-Locus coeruleus-hipocampo) na consolidação da memória de reconhecimento de objetos." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2010. http://hdl.handle.net/10183/24681.

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Existem crescentes evidências sobre a contribuição da liberação de noradrenalina (NA) central na consolidação das memórias. Teoricamente, o Núcleo do Trato Solitário (NTS) recebe informações e diversos estímulos periféricos, que são então projetados ao Núcleo Paragigantocelular (PGi). Este, por sua vez, utiliza neurotransmissores, predominantemente excitatórios, para influenciar a ativação do Locus Coeruleus (LC). Então, o LC envia projeções noradrenérgicas ao hipocampo e à amígdala, influenciando os processos mnemônicos. Aqui nós demonstramos que a inibição pelo muscimol do NTS, PGi ou LC até

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48

Conde, Gillian L. "Modulation of noradrenergic inputs to the preoptic area of the rat brain by oestradiol." Thesis, University of Cambridge, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.338066.

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49

Branger, Caroline. "Développement de molécules pour l'exploration des transporteurs des monoamines." Tours, 1995. http://www.theses.fr/1995TOUR3305.

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50

Bouret, Sébastien. "Vers une compréhension du rôle du système noradrenergique dans les processus cognitifs : étude électrophysiologique des interactions fonctionnelles entre le locus coeruleus et le cerveau antérieur chez le rat en comportement." Paris 6, 2004. http://www.theses.fr/2004PA066022.

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