Academic literature on the topic 'Norfloxacin complexes'

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Journal articles on the topic "Norfloxacin complexes"

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Fadhil, Marwa, Emad Yousif, Dina S. Ahmed, et al. "Synthesis of New Norfloxacin–Tin Complexes to Mitigate the Effect of Ultraviolet-Visible Irradiation in Polyvinyl Chloride Films." Polymers 14, no. 14 (2022): 2812. http://dx.doi.org/10.3390/polym14142812.

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Polyvinyl chloride is used in the manufacturing of a wide range of products, but it is susceptible to degradation if exposed to high temperatures and sunlight. There is therefore a need to continuously explore the design, synthesis, and application of new and improved additives to reduce the photodegradation of polyvinyl chloride in harsh environments and for outdoor applications. This research investigates the use of new norfloxacin–tin complexes as additives to inhibit the photodegradation of polyvinyl chloride to make it last longer. Reactions between norfloxacin and substituted tin chlorid
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Sinha, Rajeev K. "Probing the Structure of Moxifloxacin and Norfloxacin by Density Functional Theory and Raman Spectroscopy-=SUP=-*-=/SUP=-." Оптика и спектроскопия 130, no. 6 (2022): 811. http://dx.doi.org/10.21883/os.2022.06.52618.40-22.

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In the present work, structures of two fluoroquinolone molecules namely Moxifloxacin and Norfloxacin are investigated using density functional theory and the Raman spectroscopy. The density functional theory calculation with B3LYP-6-31+G(d,p) level of theory reveals several structures of two molecules. The low energy stable structures of Moxifloxacin show multiple intramolecular H-bonds which could be responsible for the stabilization of these structures, however, the orientation of the (4aS, 7aS)-hexahydro-1H-pyrrolo[3,4-b]pyridin (hpb) ring determines the most stable structure. In Norfloxaci
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Fournier, Bénédicte, Xilin Zhao, Tao Lu, Karl Drlica, and David C. Hooper. "Selective Targeting of Topoisomerase IV and DNA Gyrase in Staphylococcus aureus: Different Patterns of Quinolone- Induced Inhibition of DNA Synthesis." Antimicrobial Agents and Chemotherapy 44, no. 8 (2000): 2160–65. http://dx.doi.org/10.1128/aac.44.8.2160-2165.2000.

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ABSTRACT The effect of quinolones on the inhibition of DNA synthesis inStaphylococcus aureus was examined by using single resistance mutations in parC or gyrA to distinguish action against gyrase or topoisomerase IV, respectively. Norfloxacin preferentially attacked topoisomerase IV and blocked DNA synthesis slowly, while nalidixic acid targeted gyrase and inhibited replication rapidly. Ciprofloxacin exhibited an intermediate response, consistent with both enzymes being targeted. The absence of RecA had little influence on target choice by this assay, indicating that differences in rebound (re
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Bykowska, A., R. Starosta, J. Jezierska, and M. Jeżowska-Bojczuk. "Coordination versatility of phosphine derivatives of fluoroquinolones. New CuI and CuII complexes and their interactions with DNA." RSC Advances 5, no. 98 (2015): 80804–15. http://dx.doi.org/10.1039/c5ra07483e.

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Martins, Darliane A., Ligiane R. Gouvea, Gabriel S. Vignoli Muniz, et al. "Norfloxacin and N-Donor Mixed-Ligand Copper(II) Complexes: Synthesis, Albumin Interaction, and Anti-Trypanosoma cruziActivity." Bioinorganic Chemistry and Applications 2016 (2016): 1–11. http://dx.doi.org/10.1155/2016/5027404.

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Copper(II) complexes with the first-generation quinolone antibacterial agent norfloxacin containing a nitrogen donor heterocyclic ligand 2,2′-bipyridine (bipy) or 1,10-phenanthroline (phen) were prepared and characterized by IR, EPR spectra, molar conductivity, and elemental analyses. The experimental data suggest that norfloxacin was coordinated to copper(II) through the carboxylato and ketone oxygen atoms. The interaction of the copper(II) complexes with bovine serum albumin (BSA) and human serum albumin (HSA) was investigated using fluorescence quenching of the tryptophan residues and coppe
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Liu, Xukui, Xuanhao Zhao, Yumei Li, Kangdi Zheng, Qiong Wu, and Wenjie Mei. "Microwave-Assisted Synthesis, Characterisation, and DNA-Binding Properties of RuII Complexes Coordinated by Norfloxacin as Potential Tumour Inhibitors." Australian Journal of Chemistry 72, no. 5 (2019): 400. http://dx.doi.org/10.1071/ch18637.

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Three novel norfloxacin-based ruthenium(ii) complexes, [Ru(bpy)2(NFLX)]Cl·2H2O (1), [Ru(phen)2(NFLX)]Cl·2H2O (2), and [Ru(dmbpy)2(NFLX)]Cl·2H2O (3) (bpy=2,2′-bipyridine, phen=1,10-phenanthroline, dmbpy=4,4′-dimethyl-2,2′-bipyridine, and NFLX=norfloxacin), were synthesised and characterised with electrospray ionisation mass spectrometry and 1H and 13C NMR spectroscopy. The antitumour properties were evaluated by MTT assay, and the data revealed that 2 can inhibit the growth of human lung adenocarcinoma A549 efficiently. Furthermore, the DNA-binding behaviours of these complexes were investigate
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El-Mossalamy, E. H. "Molecular Charge Transfer Complexes of Norfloxacin with Nitrobenzenes." Journal of Trace and Microprobe Techniques 21, no. 2 (2003): 259–72. http://dx.doi.org/10.1081/tma-120020261.

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Guo, Qiang, Ru-Fen Zhang, Xue-Wen Hua, et al. "Syntheses, structures, in vitro cytostatic activity and antifungal activity evaluation of four diorganotin(iv) complexes based on norfloxacin and levofloxacin." New Journal of Chemistry 46, no. 9 (2022): 4314–24. http://dx.doi.org/10.1039/d1nj05742a.

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Four organotin(iv) complexes have been designed and synthesized from the reactions of R2SnO (R = Me, Ph) with the corresponding ligands norfloxacin and levofloxacin. And the cytostatic and antifungal activity test have been done.
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Heravi, Majid M., Zeinab S. Jaddi, Hossein A. Oskooie, Shahnaz Khaleghi, and Mitra Ghassemzadeh. "Regioselective Synthesis of Quinolone Antibacterials via Borate Complex of Quinolone Carboxylic Acid." Journal of Chemical Research 2005, no. 9 (2005): 578–79. http://dx.doi.org/10.3184/030823405774308943.

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1-substituted 7-chloro-6-fluoro-4-oxo-1,2-dihydroquinoline-3-carboxylic acids were converted to borate complexes. These compounds were treated with piperazine in presence of triethylamine to afford ciprofloxacin and norfloxacin in high yields.
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Székely-Szentmiklósi, Blanka, and B. Tőkés. "Study of Cyclodextrin/Fluoroquinolone Inclusion Complexes by Capillary Electrophoresis." Acta Medica Marisiensis 59, no. 2 (2013): 107–10. http://dx.doi.org/10.2478/amma-2013-0026.

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AbstractIntroduction: In the present work we evaluated the complexation role of cyclodextrins toward fluoroquinolones in an attempt to assess their potential as new formulation additives for more efficient fluoroquinolone delivery and as selectors in capillary electrophoresis.Material and method: Guest-host interactions of two second generation quinolones, ciprofloxacin and norfloxacin with four cyclodextrins, beta-cyclodextrin (β-CD), gamma-cyclodextrin (γ-CD) and two beta-cyclodextrin derivatives, 2-hydroxypropyl beta-cyclodextrin (HP-β-CD) and randomly methylated beta-cyclodextrin (RAMEB),
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Dissertations / Theses on the topic "Norfloxacin complexes"

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Reis, Felipe Costa Claro. "Investigação química de complexos de coordenação dos antibióticos enrofloxacina e norfloxacina combinados ao íon Ru(III) e suas interações com biomoléculas alvo." Universidade de São Paulo, 2014. http://www.teses.usp.br/teses/disponiveis/59/59138/tde-18092014-101658/.

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Este trabalho tem como objetivo sintetizar e caracterizar um novo complexo mononuclear de rutênio (III) e enrofloxacina (enro, fármaco antibacteriano da família das fluoroquinolonas), [Ru(enro)3].nH2O. Foram testadas várias rotas sintéticas e apenas a partir de uma delas obteve-se o composto desejado. O produto foi caracterizado pelas técnicas espectroscópicas de absorção na região do UV-visível e do infra-vermelho. Através desta última técnica foi possível determinar o modo pelo qual a enrofloxacina se coordena ao íon rutênio: a coordenação ocorre de modo bidentado através do oxigênio da piri
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Book chapters on the topic "Norfloxacin complexes"

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Kameswaran, Srinivasan, and Bellamkonda Ramesh. "Natural QSIs for Biofilm Control in Pathogenic Bacteria." In Quorum Quenching. Royal Society of Chemistry, 2023. http://dx.doi.org/10.1039/bk9781837671380-00105.

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Multidrug resistant strains of bacteria and fungi have emerged as a result of improper use of antibiotics in both humans and animals, despite the fact that the development of antibiotics has decreased morbidity and death caused by infectious diseases. Staphylococcus aureus is the pathogen of most concern when it comes to antibiotic resistance because of its inherent virulence, capacity to produce a high number of infections and ability to endure a variety of environmental circumstances. S. aureus has a variety of strategies to build antibiotic resistance, including the modification of drugs (β
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Conference papers on the topic "Norfloxacin complexes"

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Pinto Vitorino, Graciela, Cecilia Avila, Rosalía Ayala Gómez, María Cecilia Becerra, and María Rosa Mazzieri. "Supramolecular complex of norfloxacin and sulfamethoxazole: Synthesis, characterization, and evaluation of the antibacterial activity." In 4th International Electronic Conference on Medicinal Chemistry. MDPI, 2018. http://dx.doi.org/10.3390/ecmc-4-05614.

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