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Journal articles on the topic 'Norfloxacin complexes'

Author: Grafiati

Published: 5 June 2025

Last updated: 1 August 2025

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1

Fadhil, Marwa, Emad Yousif, Dina S. Ahmed, et al. "Synthesis of New Norfloxacin–Tin Complexes to Mitigate the Effect of Ultraviolet-Visible Irradiation in Polyvinyl Chloride Films." Polymers 14, no. 14 (2022): 2812. http://dx.doi.org/10.3390/polym14142812.

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Polyvinyl chloride is used in the manufacturing of a wide range of products, but it is susceptible to degradation if exposed to high temperatures and sunlight. There is therefore a need to continuously explore the design, synthesis, and application of new and improved additives to reduce the photodegradation of polyvinyl chloride in harsh environments and for outdoor applications. This research investigates the use of new norfloxacin–tin complexes as additives to inhibit the photodegradation of polyvinyl chloride to make it last longer. Reactions between norfloxacin and substituted tin chlorid

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2

Sinha, Rajeev K. "Probing the Structure of Moxifloxacin and Norfloxacin by Density Functional Theory and Raman Spectroscopy-=SUP=-*-=/SUP=-." Оптика и спектроскопия 130, no. 6 (2022): 811. http://dx.doi.org/10.21883/os.2022.06.52618.40-22.

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In the present work, structures of two fluoroquinolone molecules namely Moxifloxacin and Norfloxacin are investigated using density functional theory and the Raman spectroscopy. The density functional theory calculation with B3LYP-6-31+G(d,p) level of theory reveals several structures of two molecules. The low energy stable structures of Moxifloxacin show multiple intramolecular H-bonds which could be responsible for the stabilization of these structures, however, the orientation of the (4aS, 7aS)-hexahydro-1H-pyrrolo[3,4-b]pyridin (hpb) ring determines the most stable structure. In Norfloxaci

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3

Fournier, Bénédicte, Xilin Zhao, Tao Lu, Karl Drlica, and David C. Hooper. "Selective Targeting of Topoisomerase IV and DNA Gyrase in Staphylococcus aureus: Different Patterns of Quinolone- Induced Inhibition of DNA Synthesis." Antimicrobial Agents and Chemotherapy 44, no. 8 (2000): 2160–65. http://dx.doi.org/10.1128/aac.44.8.2160-2165.2000.

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ABSTRACT The effect of quinolones on the inhibition of DNA synthesis inStaphylococcus aureus was examined by using single resistance mutations in parC or gyrA to distinguish action against gyrase or topoisomerase IV, respectively. Norfloxacin preferentially attacked topoisomerase IV and blocked DNA synthesis slowly, while nalidixic acid targeted gyrase and inhibited replication rapidly. Ciprofloxacin exhibited an intermediate response, consistent with both enzymes being targeted. The absence of RecA had little influence on target choice by this assay, indicating that differences in rebound (re

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4

Bykowska, A., R. Starosta, J. Jezierska, and M. Jeżowska-Bojczuk. "Coordination versatility of phosphine derivatives of fluoroquinolones. New CuI and CuII complexes and their interactions with DNA." RSC Advances 5, no. 98 (2015): 80804–15. http://dx.doi.org/10.1039/c5ra07483e.

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5

Martins, Darliane A., Ligiane R. Gouvea, Gabriel S. Vignoli Muniz, et al. "Norfloxacin and N-Donor Mixed-Ligand Copper(II) Complexes: Synthesis, Albumin Interaction, and Anti-Trypanosoma cruziActivity." Bioinorganic Chemistry and Applications 2016 (2016): 1–11. http://dx.doi.org/10.1155/2016/5027404.

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Copper(II) complexes with the first-generation quinolone antibacterial agent norfloxacin containing a nitrogen donor heterocyclic ligand 2,2′-bipyridine (bipy) or 1,10-phenanthroline (phen) were prepared and characterized by IR, EPR spectra, molar conductivity, and elemental analyses. The experimental data suggest that norfloxacin was coordinated to copper(II) through the carboxylato and ketone oxygen atoms. The interaction of the copper(II) complexes with bovine serum albumin (BSA) and human serum albumin (HSA) was investigated using fluorescence quenching of the tryptophan residues and coppe

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6

Liu, Xukui, Xuanhao Zhao, Yumei Li, Kangdi Zheng, Qiong Wu, and Wenjie Mei. "Microwave-Assisted Synthesis, Characterisation, and DNA-Binding Properties of RuII Complexes Coordinated by Norfloxacin as Potential Tumour Inhibitors." Australian Journal of Chemistry 72, no. 5 (2019): 400. http://dx.doi.org/10.1071/ch18637.

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Three novel norfloxacin-based ruthenium(ii) complexes, [Ru(bpy)2(NFLX)]Cl·2H2O (1), [Ru(phen)2(NFLX)]Cl·2H2O (2), and [Ru(dmbpy)2(NFLX)]Cl·2H2O (3) (bpy=2,2′-bipyridine, phen=1,10-phenanthroline, dmbpy=4,4′-dimethyl-2,2′-bipyridine, and NFLX=norfloxacin), were synthesised and characterised with electrospray ionisation mass spectrometry and 1H and 13C NMR spectroscopy. The antitumour properties were evaluated by MTT assay, and the data revealed that 2 can inhibit the growth of human lung adenocarcinoma A549 efficiently. Furthermore, the DNA-binding behaviours of these complexes were investigate

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7

El-Mossalamy, E. H. "Molecular Charge Transfer Complexes of Norfloxacin with Nitrobenzenes." Journal of Trace and Microprobe Techniques 21, no. 2 (2003): 259–72. http://dx.doi.org/10.1081/tma-120020261.

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8

Guo, Qiang, Ru-Fen Zhang, Xue-Wen Hua, et al. "Syntheses, structures, in vitro cytostatic activity and antifungal activity evaluation of four diorganotin(iv) complexes based on norfloxacin and levofloxacin." New Journal of Chemistry 46, no. 9 (2022): 4314–24. http://dx.doi.org/10.1039/d1nj05742a.

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Four organotin(iv) complexes have been designed and synthesized from the reactions of R2SnO (R = Me, Ph) with the corresponding ligands norfloxacin and levofloxacin. And the cytostatic and antifungal activity test have been done.

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9

Heravi, Majid M., Zeinab S. Jaddi, Hossein A. Oskooie, Shahnaz Khaleghi, and Mitra Ghassemzadeh. "Regioselective Synthesis of Quinolone Antibacterials via Borate Complex of Quinolone Carboxylic Acid." Journal of Chemical Research 2005, no. 9 (2005): 578–79. http://dx.doi.org/10.3184/030823405774308943.

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1-substituted 7-chloro-6-fluoro-4-oxo-1,2-dihydroquinoline-3-carboxylic acids were converted to borate complexes. These compounds were treated with piperazine in presence of triethylamine to afford ciprofloxacin and norfloxacin in high yields.

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10

Székely-Szentmiklósi, Blanka, and B. Tőkés. "Study of Cyclodextrin/Fluoroquinolone Inclusion Complexes by Capillary Electrophoresis." Acta Medica Marisiensis 59, no. 2 (2013): 107–10. http://dx.doi.org/10.2478/amma-2013-0026.

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AbstractIntroduction: In the present work we evaluated the complexation role of cyclodextrins toward fluoroquinolones in an attempt to assess their potential as new formulation additives for more efficient fluoroquinolone delivery and as selectors in capillary electrophoresis.Material and method: Guest-host interactions of two second generation quinolones, ciprofloxacin and norfloxacin with four cyclodextrins, beta-cyclodextrin (β-CD), gamma-cyclodextrin (γ-CD) and two beta-cyclodextrin derivatives, 2-hydroxypropyl beta-cyclodextrin (HP-β-CD) and randomly methylated beta-cyclodextrin (RAMEB),

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11

Aedo, Sandra, and Yuk-Ching Tse-Dinh. "Isolation and Quantitation of Topoisomerase Complexes Accumulated on Escherichia coli Chromosomal DNA." Antimicrobial Agents and Chemotherapy 56, no. 11 (2012): 5458–64. http://dx.doi.org/10.1128/aac.01182-12.

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ABSTRACTDNA topoisomerases are important targets in anticancer and antibacterial therapy because drugs can initiate cell death by stabilizing the transient covalent topoisomerase-DNA complex. In this study, we employed a method that uses CsCl density gradient centrifugation to separate unbound from DNA-bound GyrA/ParC inEscherichia colicell lysates after quinolone treatment, allowing antibody detection and quantitation of the covalent complexes on slot blots. Using these procedures modified from thein vivocomplexes of enzyme (ICE) bioassay, we found a correlation between gyrase-DNA complex for

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12

Khatri, Savita, Manoj Kumar, Harkesh Sehrawat, S. P. Khatkar, V. B. Taxak, and Rajesh Kumar. "Fluoroquinolones Metal Complexes as Potent Antibacterial Agents." Asian Journal of Chemistry 34, no. 5 (2022): 1055–65. http://dx.doi.org/10.14233/ajchem.2022.23600.

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In this review article, a brief discussion of fluoroquinolones (FQs) and their tendency to form metal complexes is presented. The effect of FQs-M complexes on disease causing microorganisms is also summarized. The antibacterial activity of various metal complexes of various fluoroquinolones [norfloxacin (NOR), ciprofloxacin (CIP), levofloxacin (LEVO), ofloxacin (OFL), gemifloxacin (GEMI), gatifloxacin (GATI), moxifloxacin (MOX), enrofloxacin (ENRO), sparfloxacin (SPRX)] is reviewed by comparing zone of inhibition and MIC values of metal complexes. It is found to be either corresponding with th

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13

Praveen, Choubey, and Singh Pramila. "Physicochemical and biological studies on manganese( II)- and zinc(II)-norfloxacin complexes." Journal of Indian Chemical Society Vol. 80, Jan 2003 (2003): 40–41. https://doi.org/10.5281/zenodo.5835638.

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Department of Chemistry, Dr. H. S. Gour University, Sagar-470 003. India <em>E-mail :</em> drpsingh2000@yahoo.com praveenchoubey@ rediffmail.com <em>Manuscript received 21 January 2002. revised 6 August 2002. accepted 27 August 2002</em> Complexes of Mn<sup>II</sup> and Zn<sup>II</sup> with norfloxacin, an antibacterial drug, have been prepared and screened for their antibacterial and antifungal activities.

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14

Khallow, Khalaf I., and Amaal Y. R. Al-Assaf. "Synthesis and Characterization of Oxozirconium(IV), Dioxomolybdenum(VI) and Dioxotungsten(VI) with Ciprofloxacin and Norfloxacin Complexes." E-Journal of Chemistry 8, no. 2 (2011): 576–80. http://dx.doi.org/10.1155/2011/142646.

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The interaction of quinolone drugs, ciprofloxacin (CIPH) and norfloxacin (NORH), with zirconyl chloride octahydrate, sodium molybdate dihydrate and sodium tungstate dihydrate was investigated. Elemental analysis, FTIR spectral, electrical conductivity, magnetic susceptibility and UV Visible spectroscopy measurements have been used to characterize the isolated complexes. The results support the formation of two types of complexes of formula [ZrO(H2O)L2]3H2O and [MO2L2] where L = CIP and NOR; M = Mo and W. FTIR spectra of both types of complexes suggest that CIP and NOR act as deprotonated biden

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15

Korkuna, Olha, Tetyana Zhak, and Maria Smolinska. "Ion-pair complexes formation between fluoroquinolone antibiotics and methyl red and their use for the extraction-spectrophotometric analysis." Adsorption Science & Technology 35, no. 7-8 (2017): 612–22. http://dx.doi.org/10.1177/0263617417703510.

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The new spectrophotometric methods of fluoroquinolones: enrofloxacin, norfloxacin, and ofloxacin determination with the methyl red are based on ion-pair complex formation between fluoroquinolones and methyl red in acidic medium at pH 3–4 and subsequent three times extraction of the reaction products by chloroform. The obtained orange extract has an absorbance maximum at λmax = 492 nm. Optimum conditions for the formation as well as for the extraction of ion-pair complexes between fluoroquinolones and methyl red at the presence of acetate buffer and potassium chloride solutions have been establ

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16

Huang, Yanju, Jiayin Wang, and Jun Zhang. "Synthesis and characterization of a series of complexes with enhanced visible-light photocatalytic hydrogen evolution." Journal of Chemical Research 46, no. 2 (2022): 174751982210855. http://dx.doi.org/10.1177/17475198221085541.

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The complexes [Ni(HNOR)2]n·5nH2O (1), [Cd(HNOR)2]n (2), [Zn(HNOR)2·2H2O] (3), and [Co(H2NOR)2·2H2O]n·2nNO3 (4) (H2NOR = norfloxacin) are synthesized by a hydrothermal process. The structures of the complexes are determined by single-crystal X-ray diffraction. The complexes are also characterized by infrared and elemental analysis. At the same time, the promoter catalytic properties of the complexes are studied under visible light, with complex 1 enhancing the catalytic performance of gCN from 407.4 to 914.1 μmol h−1 g−1 and complex 4 enhancing the catalytic performance of gCN from 407.4 to 943

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17

Nunes, Wilhan Donizete Gonçalves, André Luiz Carneiro Soares do Nascimento, Aniele Moura, et al. "Thermal, spectroscopic and antimicrobial activity characterization of some norfloxacin complexes." Journal of Thermal Analysis and Calorimetry 132, no. 2 (2018): 1077–88. http://dx.doi.org/10.1007/s10973-018-7019-z.

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18

Luiz, Fabricio C. L., Luciene S. Garcia, Luiz S. Goes Filho, Leticia R. Teixeira, and Sonia R. W. Louro. "Fluorescence Studies of gold(III)-Norfloxacin Complexes in Aqueous Solutions." Journal of Fluorescence 21, no. 5 (2011): 1933–40. http://dx.doi.org/10.1007/s10895-011-0892-5.

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19

Huang, Yan-Ju, and Jun Zhang. "Synthesis and characterization a series of Norfloxacin-transition metal complexes." Inorganica Chimica Acta 501 (February 2020): 119244. http://dx.doi.org/10.1016/j.ica.2019.119244.

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20

Fang, Tingting, Xi Li, Chenggang Wang, et al. "The action of norfloxacin complexes on Tetrahymena investigated by microcalorimetry." Journal of Thermal Analysis and Calorimetry 109, no. 1 (2011): 433–39. http://dx.doi.org/10.1007/s10973-011-1674-7.

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21

Shaikh, Anwar, Rajani Giridhar, Francis Megraud, and Mange Yadav. "Metalloantibiotics: Synthesis, characterization and antimicrobial evaluation of bismuth-fluoroquinolone complexes against Helicobacter pylori." Acta Pharmaceutica 59, no. 3 (2009): 259–71. http://dx.doi.org/10.2478/v10007-009-0027-6.

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Metalloantibiotics: Synthesis, characterization and antimicrobial evaluation of bismuth-fluoroquinolone complexes againstHelicobacter pyloriNovel organometallic compounds have been prepared by complexing the fluoroquinolones, norfloxacin, ofloxacin, ciprofloxacin, sparfloxacin, lomefloxacin, pefloxacin and gatifloxacin, with bismuth. The complexes were characterized by UV, IR, atomic absorption spectroscopy, elemental analysis, differential scanning calorimetry, thermogravimetric analysis and mass spectrometry. Their antibacterial potential againstHelicobacter pyloriand other microorganisms wa

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22

Pereira da Cruz, Rafael, Thiago Sampaio de Freitas, Maria do Socorro Costa та ін. "Effect of α-Bisabolol and Its β-Cyclodextrin Complex as TetK and NorA Efflux Pump Inhibitors in Staphylococcus aureus Strains". Antibiotics 9, № 1 (2020): 28. http://dx.doi.org/10.3390/antibiotics9010028.

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Efflux pumps are proteins present in the plasma membrane of bacteria, which transport antibiotics and other compounds into the extracellular medium, conferring resistance. The discovery of natural efflux pump inhibitors is a promising alternative. α-Bisabolol is a sesquiterpene isolated from several plants such as Matricaria chamomilla L. and has important properties such as antibacterial and anti-inflammatory activity. Currently, the formation of inclusion complexes with β-Cyclodextrin has been used for improving the physicochemical characteristics of the host molecule. This study evaluated t

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23

Mohammed Alsuhaibani, Amnah, Sonam Shakya, Maidul Islam, and Moamen S. Refat. "Theoretical investigation of norfloxacin hybrid compounds with silver, copper, and gold metals as potential anticancer agents." Bulletin of the Chemical Society of Ethiopia 38, no. 6 (2024): 1775–90. http://dx.doi.org/10.4314/bcse.v38i6.21.

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The strategy of drug repurposing and repositioning in developing hybrid molecules is significant in drug discovery. Norfloxacin (Nor) hybrids, part of the fluoroquinolone class of antibiotics, have demonstrated anticancer properties. Various norfloxacin metal complexes have been synthesized and evaluated for their anticancer potential through docking simulations using AutoDock Vina. To preliminarily identify potential molecular targets for these anticancer compounds, docking studies were conducted with a variety of enzymes and receptor proteins associated with the cell cycle, cell growth, and

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24

AGRAWAL, SHUCHITA. "Synthesis, Characterisation & Antimicrobial Studies of Some Metal Complexes of Norfloxacin." Journal of Ultra Chemistry 15, no. 02 (2019): 18–22. http://dx.doi.org/10.22147/juc/150202.

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25

Al-Mustafa, Jamil, and Bassam Tashtoush. "Iron(II) and Iron(III) Perchlorate Complexes of Ciprofloxacin and Norfloxacin." Journal of Coordination Chemistry 56, no. 2 (2003): 113–24. http://dx.doi.org/10.1080/0095897031000088246.

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26

Kwon, Yong-Jun, Hyun-Mee Lee, Sung-Wook Han, Dong-Jin Lee, and Tae-Sub Cho. "Thermodynamic Investigation of the Formation of Complexes between Norfloxacin and Various Mononucleotides." Bulletin of the Korean Chemical Society 32, no. 9 (2011): 3233–38. http://dx.doi.org/10.5012/bkcs.2011.32.9.3233.

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27

D'SOUZA, S. A., J. RAY, S. PANDEY, and N. UDUPA. "Absorption of Ciprofloxacin and Norfloxacin when Administered as Niosome-encapsulated Inclusion Complexes." Journal of Pharmacy and Pharmacology 49, no. 2 (1997): 145–49. http://dx.doi.org/10.1111/j.2042-7158.1997.tb06769.x.

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28

Nunes, Wilhan Donizete Gonçalves, André Luiz Carneiro Soares do Nascimento, Aniele Moura, et al. "Correction to: Thermal, spectroscopic and antimicrobial activity characterization of some norfloxacin complexes." Journal of Thermal Analysis and Calorimetry 133, no. 3 (2018): 1673. http://dx.doi.org/10.1007/s10973-018-7080-7.

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29

Upadhyay, S. K., P. Kumar, and V. Arora. "Complexes of quinolone drugs norfloxacin and ciprofloxacin with alkaline earth metal perchlorates." Journal of Structural Chemistry 47, no. 6 (2006): 1078–83. http://dx.doi.org/10.1007/s10947-006-0428-z.

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30

Qu, Zhi-Rong, Hong Zhao, Li-Xin Xing, et al. "Two Polymeric Complexes of Norfloxacin with Iron(II) and Their Magnetic Properties." European Journal of Inorganic Chemistry 2003, no. 16 (2003): 2920–23. http://dx.doi.org/10.1002/ejic.200300242.

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31

Luo, Hui, Xi Li, Chenggang Wang, et al. "Biological effect studies of norfloxacin complexes on Tetrahymena and Escherichia coli by microcalorimetry." Journal of Wuhan University of Technology-Mater. Sci. Ed. 31, no. 3 (2016): 684–88. http://dx.doi.org/10.1007/s11595-016-1429-1.

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32

Evstigneev, M. P., K. A. Rybakova, and D. B. Davies. "Formation of complexes of antimicrobial agent norfloxacin with antitumor antibiotics of anthracycline series." Russian Journal of Physical Chemistry A 81, no. 5 (2007): 802–7. http://dx.doi.org/10.1134/s0036024407050275.

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33

Chattah, Ana K., Yamila Garro Linck, Gustavo A. Monti, et al. "NMR and IR characterization of the aluminium complexes of norfloxacin and ciprofloxacin fluoroquinolones." Magnetic Resonance in Chemistry 45, no. 10 (2007): 850–59. http://dx.doi.org/10.1002/mrc.2058.

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34

Malik, Muhammad, Syed Hussain, and Karl Drlica. "Effect of Anaerobic Growth on Quinolone Lethality with Escherichia coli." Antimicrobial Agents and Chemotherapy 51, no. 1 (2006): 28–34. http://dx.doi.org/10.1128/aac.00739-06.

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ABSTRACT Quinolone activity against Escherichia coli was examined during aerobic growth, aerobic treatment with chloramphenicol, and anaerobic growth. Nalidixic acid, norfloxacin, ciprofloxacin, and PD161144 were lethal for cultures growing aerobically, and the bacteriostatic activity of each quinolone was unaffected by anaerobic growth. However, lethal activity was distinct for each quinolone with cells treated aerobically with chloramphenicol or grown anaerobically. Nalidixic acid failed to kill cells under both conditions; norfloxacin killed cells when they were grown anaerobically but not

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35

Mendes, Cassiana, Bárbara Paula Wiemes, Aline Buttchevitz та ін. "Investigation of β-cyclodextrin–norfloxacin inclusion complexes. Part 1. Preparation, physicochemical and microbiological characterization". Expert Review of Anti-infective Therapy 13, № 1 (2014): 119–29. http://dx.doi.org/10.1586/14787210.2015.982091.

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36

Mendes, Cassiana, Aline Buttchevitz, Andersson Barison та ін. "Investigation of β-cyclodextrin–norfloxacin inclusion complexes. Part 2. Inclusion mode and stability studies". Expert Review of Anti-infective Therapy 13, № 1 (2014): 131–40. http://dx.doi.org/10.1586/14787210.2015.982092.

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37

Pohlhaus, Jennifer Reineke, and Kenneth N. Kreuzer. "Norfloxacin-induced DNA gyrase cleavage complexes blockEscherichia colireplication forks, causing double-stranded breaksin vivo." Molecular Microbiology 56, no. 6 (2005): 1416–29. http://dx.doi.org/10.1111/j.1365-2958.2005.04638.x.

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38

Efthimiadou, Eleni K., George Psomas, Yiannis Sanakis, Nikos Katsaros, and Alexandra Karaliota. "Metal complexes with the quinolone antibacterial agent N-propyl-norfloxacin: Synthesis, structure and bioactivity." Journal of Inorganic Biochemistry 101, no. 3 (2007): 525–35. http://dx.doi.org/10.1016/j.jinorgbio.2006.11.020.

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39

Patel, Mohan, Deepen Gandhi, and Pradhuman Parmar. "Antibacterial, nuclease, and SOD-mimic behaviors of copper(II) complexes of norfloxacin and phenanthrolines." Journal of Coordination Chemistry 64, no. 7 (2011): 1276–88. http://dx.doi.org/10.1080/00958972.2011.566922.

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40

Fawaz, F., F. Bonini, M. Guyot, J. Bildet, M. Maury, and A. M. Lagueny. "Bioavailability of norfloxacin from PEG 6000 solid dispersion and cyclodextrin inclusion complexes in rabbits." International Journal of Pharmaceutics 132, no. 1-2 (1996): 271–75. http://dx.doi.org/10.1016/0378-5173(95)04387-x.

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41

Chattah, Ana K., Kamal H. Mroue, Laura Y. Pfund, Ayyalusamy Ramamoorthy, Marcela R. Longhi та Claudia Garnero. "Insights into Novel Supramolecular Complexes of Two Solid Forms of Norfloxacin and β-Cyclodextrin". Journal of Pharmaceutical Sciences 102, № 10 (2013): 3717–24. http://dx.doi.org/10.1002/jps.23683.

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42

Fang, Si’an, Yuhao Jiang, Di Xiao, et al. "Synthesis and Evaluation of Novel Norfloxacin Isonitrile 99mTc Complexes as Potential Bacterial Infection Imaging Agents." Pharmaceutics 13, no. 4 (2021): 518. http://dx.doi.org/10.3390/pharmaceutics13040518.

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To develop potential technetium-99m single-photon emission computed tomography (SPECT) imaging agents for bacterial infection imaging, the novel norfloxacin isonitrile derivatives CN4NF and CN5NF were synthesized and radiolabeled with a [99mTc][Tc(I)]+ core to obtain [99mTc]Tc-CN4NF and [99mTc]Tc-CN5NF. These compounds were produced in high radiolabeling yields and showed hydrophilicity and good stability in vitro. The bacterial binding assay indicated that [99mTc]Tc-CN4NF and [99mTc]Tc-CN5NF were specific to bacteria. Compared with [99mTc]Tc-CN4NF, biodistribution studies of [99mTc]Tc-CN5NF s

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43

Adebayo, Joseph, Elizabeth Balogun, O. Ajadi, Caroline Akinremi, and Joshua Obaleye. "Alterations in some organ function indices in rats administered metal complexes of ofloxacin and norfloxacin." Journal of Investigational Biochemistry 3, no. 4 (2014): 159. http://dx.doi.org/10.5455/jib.20141119115356.

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44

Ataklti, Abraha, Gholap Ashok, and Belay Abebe. "Determinations of norfloxacin complexes with caffeine, and its optical transition probabilities using UV-Vis spectroscopy." International Journal of Physical Sciences 12, no. 8 (2017): 95–102. http://dx.doi.org/10.5897/ijps2017.4611.

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45

Ponce-Ponte, Micaela, Carolina Aloisio, Diana Marcela Romero-Guerra, Sandra Gracia-Vásquez, Claudia Garnero, and Marcela Longhi. "Binary and ternary complexes of norfloxacin to improve the solubility of the active pharmaceutical ingredient." Therapeutic Delivery 9, no. 9 (2018): 639–52. http://dx.doi.org/10.4155/tde-2018-0028.

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46

Abbass, L. M., S. A. Sadeek, W. A. Zordok, M. El-Telbany, and W. H. El-Shwiniy. "Synthesis, Structure, DFT, and Biological Activity of Metal Complexes of Norfloxacin and Metformin Mixed Ligand." Russian Journal of General Chemistry 91, no. 9 (2021): 1774–82. http://dx.doi.org/10.1134/s1070363221090243.

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47

Wu, Zhelun, Zhirui Fan, and Peipei Song. "Efficient degradation of Cu-Norfloxacin complexes in wastewater by electro-activated peroxymonosulfate coupled with electrocoagulation." Journal of Water Process Engineering 70 (February 2025): 107140. https://doi.org/10.1016/j.jwpe.2025.107140.

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48

Doga, P. G., A. I. Marynin, A. V. Yegorova, Yu V. Skripinets, and V. P. Antonovich. "Influence Of The Size Of Colloid Nanorized Systems On The Luminescence Intensity Of Eu(III) And Tb(III) Complexes." Methods and Objects of Chemical Analysis 16, no. 1 (2021): 15–24. http://dx.doi.org/10.17721/moca.2021.15-24.

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Abstract:

Optimal conditions for complexation of Tb(III) ions with norfloxacin, keterolac, 2-oxo-4-hydroxyquinoline-3-carboxylic acid amide derivative and Eu(III) with oxytetracycline were established. The dependence of the luminescence intensity (Ilum) of complexes on the acidity of the medium, the type of solvent, the luminescent characteristics of complex compounds were determined, the average lifetime of the excited state of europium and terbium ions in complex compounds in the presence and absence of cationic, anionic and nonionic substances, and the size of colloidal nanoscale systems based on the

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49

Patel, Mohan N., Hardik N. Joshi, and Chintan R. Patel. "Copper(II) complexes with norfloxacin and neutral terpyridines: Cytotoxic, antibacterial, superoxide dismutase and DNA-interaction approach." Polyhedron 40, no. 1 (2012): 159–67. http://dx.doi.org/10.1016/j.poly.2012.03.050.

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50

LI, Shikun, Yanjun WANG, Qiuyue LIN, Weidong LIU, Jiehong DING, and Yunyun WANG. "Synthesis, crystal structures of novel complexes of rare earth with norfloxacin, interaction with DNA and BSA." Journal of Rare Earths 30, no. 5 (2012): 460–66. http://dx.doi.org/10.1016/s1002-0721(12)60073-8.

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