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Journal articles on the topic 'Normal delivery'

Author: Grafiati

Published: 4 June 2021

Last updated: 17 June 2025

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1

Yalla, Dheeraj, Alaka N. Nadar, and Usha Rani G. "Spontaneous broad ligament haematoma following a normal vaginal delivery." New Indian Journal of OBGYN 5, no. 2 (2019): 140–41. http://dx.doi.org/10.21276/obgyn.2019.5.2.15.

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2

Brennand, Janet E., and Andrew A. Calder. "Labor and normal delivery." Current Opinion in Obstetrics and Gynecology 3, no. 6 (1991): 764–68. http://dx.doi.org/10.1097/00001703-199112000-00004.

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3

Panni, Moeen K., and Scott Segal. "Local Anesthetic Requirements Are Greater in Dystocia Than in Normal Labor." Anesthesiology 98, no. 4 (2003): 957–63. http://dx.doi.org/10.1097/00000542-200304000-00024.

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Background Dystocia is characterized by abnormal progress of labor and is a common contemporary indication for cesarean delivery in the United States. There has been considerable controversy as to whether epidural analgesia causes dysfunctional labor leading to cesarean delivery for dystocia. The minimum local analgesic concentration (MLAC) is a clinical model used to determine the relative potencies of local anesthetics in the first stage of labor. In this article, the authors report a prospective study determining the MLAC of bupivacaine in early labor of parturients who eventually delivered either vaginally or via cesarean section. Methods An up-down sequential allocation technique was used to determine the MLAC of bupivacaine in 57 nulliparous parturients assigned to either vaginal delivery or cesarean section arms. In addition, patients were assigned to groups receiving or not receiving intravenous oxytocin at the time of epidural placement. Only patients who delivered by the assigned delivery mode were included in the MLAC analyses. Results Parturients who later delivered vaginally had 25% and 31% lower MLAC values (0.078% and 0.085% wt/vol bupivacaine, receiving or not receiving intravenous oxytocin, respectively) than those who later delivered by cesarean section (0.102% and 0.106% wt/vol bupivacaine, receiving or not receiving intravenous oxytocin, respectively). Conclusions These data suggest that an increased local anesthetic requirement for epidural labor analgesia is associated with more intense pain related to dystocia. Women in early, clinically normal labor but who later develop dystocia require more local anesthetic and, by inference, are experiencing more severe pain than women who deliver vaginally. This association should be considered when studying the relation between the method of labor analgesia and the course of labor.

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4

Manapatt, Asokan Keloth, Latha Anoop, Deepna Tharammal, Aiswarya Sathyapal, and Yasmeen Muneer. "Pattern of Prolactin Secretion after Normal Vaginal Delivery and in Cesarean Delivery." International Journal of Infertility & Fetal Medicine 5, no. 1 (2014): 15–17. http://dx.doi.org/10.5005/jp-journals-10016-1074.

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ABSTRACT Prolactin (PRL) is hormone of multiple biological actions and is best known for its role in milk production. This hospital-based study was undertaken to review the impact of PRL hormone in vaginal delivery and cesarean delivery. Our study is meant to create awareness in the society to promote breast feeding and the importance of promoting normal vaginal delivery whenever possible. In this study, we investigated the serum PRL values using enzyme-linked immunoflow assay method in 101 women who underwent normal (56) and cesarean delivery (45) in obstetrics and gynecology department of Kannur Medical College, Anjarakandy. Serum PRL at 24 and 48 hours blood sample was estimated among the two groups, mean PRL in vaginal delivery 24 hours 359.46 ± 119.70 ng/ml, 48 hours 386.67 ± 135.66 ng/ ml and in cesarean delivery 24 hours 245.49 ± 115.49 ng/ml, 48 hours 282.92 ± 69.59 ng/ml. The values of serum PRL are found to be significantly higher in the vaginal delivery group (p < 0.001) as compared with the cesarean section group. Through this study, we concluded that the mothers who delivered by cesarean section had decreased PRL levels than the women who delivered vaginally which may have a significant role in establishment of breastfeeding. How to cite this article Manapatt AK, Anoop L, Tharammal D, Sathyapal A, Muneer Y. Pattern of Prolactin Secretion after Normal Vaginal Delivery and in Cesarean Delivery. Int J Infertility Fetal Med 2014;5(1):15-17.

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Steele, E. Kristine, and D. S. Lowry. "Labial adhesions following normal delivery." Journal of Obstetrics and Gynaecology 22, no. 5 (2002): 555. http://dx.doi.org/10.1080/0144361021000003771.

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6

Griffith, H. B., and J. C. Barnes. "Hamman's syndrome after a normal delivery." Journal of Obstetrics and Gynaecology 7, no. 4 (1987): 272–73. http://dx.doi.org/10.1080/01443615.1987.12088602.

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7

Hofer, Jennifer E., and Barbara M. Scavone. "Microparticle Release During Normal Cesarean Delivery." Anesthesia & Analgesia 126, no. 3 (2018): 925–27. http://dx.doi.org/10.1213/ane.0000000000002290.

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8

KIANI, MOHAMMAD F., RAMIN ANSARI, and M. WALEED GABER. "Oxygen Delivery in Irradiated Normal Tissue." Journal of Radiation Research 44, no. 1 (2003): 15–21. http://dx.doi.org/10.1269/jrr.44.15.

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9

SHAH, P. N., V. A. RANE, and A. S. MOOLGAOKER. "Retroperitoneal abscess complicating a normal delivery." BJOG: An International Journal of Obstetrics and Gynaecology 99, no. 2 (1992): 160–61. http://dx.doi.org/10.1111/j.1471-0528.1992.tb14479.x.

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Hofer, J. E., and B. M. Scavone. "Microparticle Release During Normal Cesarean Delivery." Obstetric Anesthesia Digest 38, no. 3 (2018): 137. http://dx.doi.org/10.1097/01.aoa.0000542357.94577.7b.

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11

Robson, S. C., R. J. Boys, S. Hunter, and W. Dunlop. "Maternal Hemodynamics After Normal Delivery and Delivery Complicated by Postpartum Hemorrhage." Obstetric Anesthesia Digest 10, no. 1 (1990): 14. http://dx.doi.org/10.1097/00132582-199004000-00018.

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12

Brown, Simon, Kim Hinshaw, and Mark Millins. "Clinical Practice Guideline Update—Birth Imminent: Normal Delivery and Delivery Complications." Journal of Paramedic Practice 6, no. 1 (2014): 12–13. http://dx.doi.org/10.12968/jpar.2014.6.1.12.

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13

Shembekar, Chaitanya A., Shantanu C. Shembekar, Manisha C. Shembekar, Parul Sharma Saoji, and Jayshree J. Upadhye. "Maternal body mass index: how much it affects mother and baby." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 9, no. 3 (2020): 1050. http://dx.doi.org/10.18203/2320-1770.ijrcog20200873.

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Background: Overweight, obesity, and morbid obesity in the mother are associated with adverse obstetrics well as neonatal outcome. Aim of this study was to assess the prevalence of overweight and obesity, and the impact of body mass index (BMI) on maternal and neonatal outcome.Methods: This is a retrospective study from January 2018 to September 2018 on 180 women with singleton term pregnancies. Maternal and neonatal outcomes at delivery were noted.Results: In present study, 3 (1.66%) pregnant women were underweight, 57 (31.66%) pregnant women had normal BMI, 71 (39.44%) pregnant women were overweight while 49 (27.22%) pregnant women were obese. Gestational weight gain was less than 8 kgs in 40 (22.22%) pregnant women, weight gain was 8-15.9 kgs in 132 (73.33%) pregnant women while weight gain was more than 16 kgs in 8 (4.44%) pregnant women. Out of 3 underweight women, 1 delivered by cesarean section and 2 had normal delivery, out of 57 women with normal BMI, 21 delivered by cesarean section and 36 had normal delivery, out of 71 overweight women, 47 delivered by cesarean section and 34 had normal delivery while out of 49 obese women, 38 delivered by cesarean section and 11 had normal delivery. PET and GDM was seen in 9 (7.5%) women each while macrosomia were seen in 5 (4.16%) women.Conclusions: Increased association was seen with maternal obesity and adverse outcome of pregnancy like PIH, GDM, cesarean section.

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14

Yoong, Ann, and B. Alderman. "A Large Labial Adhesion following Normal Delivery." Acta Obstetricia et Gynecologica Scandinavica 69, no. 5 (1990): 443. http://dx.doi.org/10.3109/00016349009013311.

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15

Diana, Valsa, and Bhargavi K. "Spontaneous isolated bladder rupture following normal delivery." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 7, no. 4 (2018): 1638. http://dx.doi.org/10.18203/2320-1770.ijrcog20181354.

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Spontaneous bladder rupture in a primipara after normal delivery within the first week of puerperium is a rare surgical emergency. The importance of suspecting and recognizing the voiding dysfunction in the postpartum period and early catheterisation to prevent such catastrophe is highlighted in this case report. We report a case of spontaneous intraperitoneal bladder rupture in a 26 year old primipara 3 days after normal delivery of a 3kg baby with episiotomy

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16

Muthulakshmi, B., I. Francis, A. Magos, M. Roy, and A. Watkinson. "Broad ligament haematoma after a normal delivery." Journal of Obstetrics and Gynaecology 23, no. 6 (2003): 669–70. http://dx.doi.org/10.1080/01443610310001607887.

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17

Sharma, B., R. Arora, and J. Preston. "Postpartum labial adhesions following normal vaginal delivery." Journal of Obstetrics and Gynaecology 25, no. 2 (2005): 215. http://dx.doi.org/10.1080/01443610500051262.

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18

Kibel, Adam S., David R. Staskin, and Victor E. Grigoriev. "Intraperitoneal Bladder Rupture After Normal Vaginal Delivery." Journal of Urology 153, no. 3 (1995): 725–27. http://dx.doi.org/10.1016/s0022-5347(01)67699-7.

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19

Berlinerblau, Rubin, Annie Yessian, Edgar Lichstein, Shoshana Haberman, Edward Oruci, and Raymond Jewelewicz. "Maternal Arrhythmias of Normal Labor and Delivery." Gynecologic and Obstetric Investigation 52, no. 2 (2001): 128–31. http://dx.doi.org/10.1159/000052957.

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20

Cerezo-Ruiz, Antonio, Antonio Luque-Molina, Rafael Gimenez-Domenech, and Antonio Naranjo-Rodriguez. "Attendance to a “normal delivery” of choledocholithiasis." Turkish Journal of Gastroenterology 30, no. 12 (2020): 1072–73. http://dx.doi.org/10.5152/tjg.2019.19362.

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21

Antoine, Jasmine. "The not-so-normal delivery: Neonatal resuscitation." Emergency Medicine Australasia 28, no. 5 (2016): 493–95. http://dx.doi.org/10.1111/1742-6723.12663.

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22

Gupta, A., A. Johnson, A. Johansson, G. Berg, and C. Lennmarken. "Maternal respiratory function following normal vaginal delivery." International Journal of Obstetric Anesthesia 2, no. 3 (1993): 129–33. http://dx.doi.org/10.1016/0959-289x(93)90004-2.

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23

Behera, C., Ravi Rautji, and T. D. Dogra. "Full term normal delivery following suicidal hanging." Forensic Science International 169, no. 1 (2007): e1-e2. http://dx.doi.org/10.1016/j.forsciint.2007.01.018.

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24

Ouzounian, Joseph G., and Uri Elkayam. "Physiologic Changes During Normal Pregnancy and Delivery." Cardiology Clinics 30, no. 3 (2012): 317–29. http://dx.doi.org/10.1016/j.ccl.2012.05.004.

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25

Widayati, Erna Fitri, and Pariyanti Pariyanti. "Delivery Service Pustakawan Di Era New Normal." Pustakaloka 12, no. 2 (2020): 152–70. http://dx.doi.org/10.21154/pustakaloka.v12i2.2321.

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26

Zhang, Hong-Yu, Ren-Fei Guo, Yan Wu, and Yi Ling. "Normal Range of Head-to-body Delivery Interval by Two-step Delivery." Chinese Medical Journal 129, no. 9 (2016): 1066–71. http://dx.doi.org/10.4103/0366-6999.180522.

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27

Lubusky, Marek, Ondrej Simetka, Martina Studnickova, Martin Prochazka, Marta Ordeltova, and Katherine Vomackova. "Fetomaternal hemorrhage in normal vaginal delivery and in delivery by cesarean section." Transfusion 52, no. 9 (2012): 1977–82. http://dx.doi.org/10.1111/j.1537-2995.2011.03536.x.

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28

Yalla, Dheeraj, Alka N. Nadar, and G. Usha Rani. "Spontaneous broad ligament haematoma following a normal vaginal delivery: a case report." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 7, no. 6 (2018): 2521. http://dx.doi.org/10.18203/2320-1770.ijrcog20182383.

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Broad ligament haematoma is a rare complication following a normal vaginal delivery. We report one such case of a woman who developed this complication within 3 hrs of normal vaginal delivery. She is G2P1L1, 38 wks GA, in active labour. Pt was allowed for spontaneous progression of labour, following which she delivered vaginally. Within 3 hrs patient looked clinically very pale with vitals being deranged and complains of inability to void urine, severe perineal pain. On basis of clinical examination and transabdominal ultrasound features a diagnosis of right sided broad ligament haematoma was made. Based on patients haemodynamic instability surgical management in the form of obstetric hysterectomy was done.

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29

Cattaneo, Ruggero, Annalisa Monaco, Oriana Streni, Vittorio Serafino, and Mario Giannoni. "Birth delivery trauma and malocclusion." Journal of Clinical Pediatric Dentistry 29, no. 3 (2005): 185–88. http://dx.doi.org/10.17796/jcpd.29.3.925q02q3267m16l7.

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The aim of the investigation was to determine the dynamic of birth delivery and relate to dental occlusion among a group of adult subjects. The group studied was made up of 106 subjects (57 females and 49 males) referred for dental diagnosis and treatment. The average age was 26 with a range 22 to 30 years. In data collection and analysis the following were used as measures: dental occlusion (Angle Class I, II div 1, II div 2 and III) and type of delivery (normal, short, long, caesarean and other). Results showed that among 106 subjects 72 (68%) had malocclusion versus 34 (32%) with normal occlusion; 24 subjects (22.6%) have been normal delivery versus 82 (77.4%) with non-normal delivery. Class I is present in 34 subjects (32%), class II division 1 in 26 (24%), class II division 2 in 22 (20%), class III in 16 (14%), and 8 subjects (6%) fall in the section "other". Among 24 subjects with normal delivery 100% presented class I occlusion. However, among 82 subjects with non-normal delivery 10 subjects had a class I (12.2%) and the 72 (87.8%) had in the other classes, are distributed in the various subgroups of non-normal labor/delivery. None of the subjects with a malocclusion have a normal labor/delivery. Better understanding of the connections among osteopathic theory, craniosacral treatment and the outcomes upon dental occlusion, more rigorous evaluations are warranted.

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Gudura, Tafese Tadele, Alemu Tamiso Debiso, and Tariku Tadele Gudura. "Factors associated with Institutional delivery in Boricha district of Sidama zone, southern Ethiopia." International Journal of Public Health Science (IJPHS) 3, no. 4 (2014): 224. http://dx.doi.org/10.11591/ijphs.v3i4.4696.

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<p style="color: #000000; font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 10px; font-style: normal; font-variant-ligatures: normal; font-variant-caps: normal; font-weight: 400; letter-spacing: normal; orphans: 2; text-align: start; text-indent: 0px; text-transform: none; white-space: normal; widows: 2; word-spacing: 0px; -webkit-text-stroke-width: 0px; text-decoration-style: initial; text-decoration-color: initial;">Every year, 40 million women give birth at home without the help of a<br />skilled birth attendant. In 2011, 287,000 women died during pregnancy or childbirth. Almost all these deaths occur in developing countries where mothers and children lack access to basic health care. Reports showed the low utilization of health facility for delivery service in Ethiopia. This study aimed to determine the utilization and factors influencing institutional delivery. Community based cross sectional study was conducted from January to February 2013/14 in Boricha District of Southern Ethiopia among mothers who gave birth in the last 1 year. Multistage sampling techniques were used to collect data from 546 mothers. Taking in to account place of birth for the last child, only 4.9% women gave birth in a health facility. Women’s education level (AOR=4.4 (95% CI=1.36-14.33)), timing of firstANC visit (AOR= .03 (95% CI=0.004 - 0.205)), women’s advice to deliver in a health facility during ANC (AOR = 31.15 (95% CI=2.02-479.52)), women’s knowledge of birth related complications (AOR= 12.4 (95% CI=2.67-57.16)) and decision making power (AOR=0.2 (95% CI=0.060.82)) showed significant association with institutionional delivery. Institutional delivery in the study area was found to be very low. Raising awareness on institutional delivery to maximize delivery service utilization and strengthening provision of education and counseling to deliver in health facility during antenatal care visits at individual and community level should be given due emphasis.</p>

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31

Gudura, Tafese Tadele, Alemu Tamiso Debiso, and Tariku Tadele Gudura. "Factors associated with Institutional delivery in Boricha district of Sidama zone, southern Ethiopia." International Journal of Public Health Science (IJPHS) 3, no. 4 (2014): 224. http://dx.doi.org/10.11591/.v3i4.4696.

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<p style="color: #000000; font-family: Verdana, Arial, Helvetica, sans-serif; font-size: 10px; font-style: normal; font-variant-ligatures: normal; font-variant-caps: normal; font-weight: 400; letter-spacing: normal; orphans: 2; text-align: start; text-indent: 0px; text-transform: none; white-space: normal; widows: 2; word-spacing: 0px; -webkit-text-stroke-width: 0px; text-decoration-style: initial; text-decoration-color: initial;">Every year, 40 million women give birth at home without the help of a<br />skilled birth attendant. In 2011, 287,000 women died during pregnancy or childbirth. Almost all these deaths occur in developing countries where mothers and children lack access to basic health care. Reports showed the low utilization of health facility for delivery service in Ethiopia. This study aimed to determine the utilization and factors influencing institutional delivery. Community based cross sectional study was conducted from January to February 2013/14 in Boricha District of Southern Ethiopia among mothers who gave birth in the last 1 year. Multistage sampling techniques were used to collect data from 546 mothers. Taking in to account place of birth for the last child, only 4.9% women gave birth in a health facility. Women’s education level (AOR=4.4 (95% CI=1.36-14.33)), timing of firstANC visit (AOR= .03 (95% CI=0.004 - 0.205)), women’s advice to deliver in a health facility during ANC (AOR = 31.15 (95% CI=2.02-479.52)), women’s knowledge of birth related complications (AOR= 12.4 (95% CI=2.67-57.16)) and decision making power (AOR=0.2 (95% CI=0.060.82)) showed significant association with institutionional delivery. Institutional delivery in the study area was found to be very low. Raising awareness on institutional delivery to maximize delivery service utilization and strengthening provision of education and counseling to deliver in health facility during antenatal care visits at individual and community level should be given due emphasis.</p>

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32

Mehta, Kalpana, Dhanesh Kumar, Dharmendra Singh Fathepuriya, and Leena Verma. "Incidence of cesarean delivery after induction of labour with dinoprostone gel at term in nulliparous women with unfavourable bishops score." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 6, no. 4 (2017): 1253. http://dx.doi.org/10.18203/2320-1770.ijrcog20170956.

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Background: The aim of induction of labour is to achieve vaginal delivery in advance of the normal timing of parturition and to avoid operative delivery. The objective was to study the incidence of instrumental delivery and cesarean section in nulliparous women with unfavourable bishops score at term.Methods: This study was conducted on 200 patients in nulliparous women with unfavourable bishop score, cephalic presentation and no previous history of abortion.Results: The most frequent cause of induction of labour was postdatism (47.5%) followed by PIH (25.5%) and PROM (13%). 143 (71.5%) women had normal vaginal delivery whereas in 54 women (27%) cesarean section was done. 2 women (1%) had forceps application for delivery and remaining 1 women (0.5%) had ventouse delivery. Out of 200 patients 9 had maternal complication of induction of labour.Conclusions: In present study 71.5% women had normal vaginal delivery, 27% had cesarean section. Mean bishop score at induction was 3.31 which improved to 4.0 after 12 hours of gel instillation. The mean induction to delivery interval was 13.38 hrs in present study, 54.5% patients were delivered within 12 hours of gel instillation in this study. Most common indication of cesarean section was failed progress followed by fetal distress.

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33

Rajuddin and Afifi. "Uterine Inversion After Normal Delivery; A Case Report." Indian Journal of Public Health Research & Development 9, no. 12 (2018): 1941. http://dx.doi.org/10.5958/0976-5506.2018.02273.8.

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34

Thérèse, Delvaux, Aké-Tano Odile, Gohou-Kouassi Valérie, Bosso Patrice, Collin Simon, and Ronsmans Carine. "Quality of Normal Delivery Care in Côte d'Ivoire." African Journal of Reproductive Health 11, no. 1 (2007): 22. http://dx.doi.org/10.2307/30032485.

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35

SHAHABI, S. "Primary psoas abscess complicating a normal vaginal delivery." Obstetrics & Gynecology 99, no. 5 (2002): 906–9. http://dx.doi.org/10.1016/s0029-7844(01)01699-4.

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36

Rojas-Marte, Geurys, Anand Rai, On Chen, Sameer Chadha, Vijay Shetty, and Jacob Shani. "A Dreadful Trilogy Complicating a Normal Vaginal Delivery." Chest 146, no. 4 (2014): 288A. http://dx.doi.org/10.1378/chest.1992413.

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Shahabi, Shohreh, Joshua P. Klein, and Paolo F. Rinaudo. "Primary Psoas Abscess Complicating a Normal Vaginal Delivery." Obstetrics & Gynecology 99, no. 5, Part 2 (2002): 906–9. http://dx.doi.org/10.1097/00006250-200205001-00014.

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Akkanti, Bindu, Karthik Kovvuru, Swetha Rao, Kalpalatha Guntupalli, and Prasad Manian. "NOT SO NORMAL VAGINAL DELIVERY: TRAUMATIC DIAPHRAGMATIC RUPTURE." Chest 136, no. 4 (2009): 55S. http://dx.doi.org/10.1378/chest.136.4_meetingabstracts.55s-d.

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A. BUTLER-MANUEL, CATHERINE MORLEY-, S. "Fatal neonatal subdural haemorrhage following normal vaginal delivery." Journal of Obstetrics and Gynaecology 17, no. 6 (1997): 584. http://dx.doi.org/10.1080/01443619768696.

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40

Kovo, Michal, Iris Eshed, and Gustavo Malinger. "Broad ligament hematoma following a normal vaginal delivery." Gynecological Surgery 3, no. 2 (2006): 138–40. http://dx.doi.org/10.1007/s10397-006-0184-2.

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41

Aderi, Aderi, Yayi Suryo Prabandari, and Atik Triratnawati. "Merasa aman karena dianggap normal, kemudahan dan kepasrahan sebagai alasan ibu-ibu memilih persalinan rumah di desa: Studi Kualitatif di Kalimantan Tengah." Berita Kedokteran Masyarakat 32, no. 6 (2016): 203. http://dx.doi.org/10.22146/bkm.6646.

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Feeling safe due to normal antenatal care, easier to going to health facility, and compliance to God decision as reasons for home delivery choice among village mothers: a qualitative study in Central KalimantanPurposeThe purpose of this paper was to explore mothers’ perceptions of delivery at home in Kartika Bhakti Village, Province of Central Kalimantan. MethodsA case study was conducted involving observations, in-depth interviews and focus group discussion with 7 maternity women, 1 maternity women’s husbands, 1 village midwife, 1 community leader and 1 midwife of the village health post in Kartika Bhakti village, Province of Central Kalimantan.ResultsThe study found six reasons why mothers tended to choose to do delivery at home: barriers to delivery at health facilities; attitudes and preparedness of the midwife to deliver home deliveries; delivery at home benefits; based on the results of the pregnancy examination; not afraid of the risks of delivery; and ready to accept the dangers and risks of delivery.ConclusionThe reasons will be used as a consideration for choosing the birthplace. When the results of a pregnancy examination is good, mothers will tend to choose a home delivery. Furthermore, obstacles in health facilities such as barriers in health centers, geographical, hospital barriers, no postpartum services, and economic abilities are also some of the main reasons to choose to deliver at home. Health education and approaches related to delivery safety need to be improved to change mothers’ perceptions.

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Kaku, Shoji, Fuminori Kimura, and Takashi Murakami. "Management of Fetal Growth Arrest in One of Dichorionic Twins: Three Cases and a Literature Review." Obstetrics and Gynecology International 2015 (2015): 1–4. http://dx.doi.org/10.1155/2015/289875.

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Progressive fetal growth restriction (FGR) is often an indication for delivery. In dichorionic diamniotic (DD) twin pregnancy with growth restriction only affecting one fetus (selective fetal growth restriction: sFGR), the normal twin is also delivered prematurely. There is still not enough evidence about the optimal timing of delivery for DD twins with sFGR in relation to discordance and gestational age. We report three sets of DD twins with sFGR (almost complete growth arrest affecting one fetus for ≥2 weeks) before 30 weeks of gestation. The interval from growth arrest to delivery was 21–24 days and the discordance was 33.7–49.8%. A large-scale study showed no difference of overall mortality or the long-term outcome between immediate and delayed delivery for FGR, while many studies have identified a risk of developmental delay following delivery of the normal growth fetus before 32 weeks. Therefore, delivery of DD twins with sFGR should be delayed if the condition of the sFGR fetus permits in order to increase the gestational age of the normal growth fetus.

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Roti, Giovanni, Jun Qi, Samuel Kitara, et al. "Leukemia-specific delivery of mutant NOTCH1 targeted therapy." Journal of Experimental Medicine 215, no. 1 (2017): 197–216. http://dx.doi.org/10.1084/jem.20151778.

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On-target drug delivery remains a challenge in cancer precision medicine; it is difficult to deliver a targeted therapy to cancer cells without incurring toxicity to normal tissues. The SERCA (sarco-endoplasmic reticulum Ca2+ ATPase) inhibitor thapsigargin inhibits mutant NOTCH1 receptors compared with wild type in T cell acute lymphoblastic leukemia (T-ALL), but its administration is predicted to be toxic in humans. Leveraging the addiction of ALL to folic acid, we conjugated folate to an alcohol derivative of thapsigargin via a cleavable ester linkage. JQ-FT is recognized by folate receptors on the plasma membrane and delivered into leukemia cells as a potent antileukemic agent. In mechanistic and translational models of T-ALL, we demonstrate NOTCH1 inhibition in vitro and in vivo. These proof-of-concept studies support the further optimization of this first-in-class NOTCH1 inhibitor with dual selectivity: leukemia over normal cells and NOTCH1 mutants over wild-type receptors. Furthermore, tumor-specific disruption of Notch signaling may overcome legitimate concerns associated with the tumor suppressor function of nontargeted Notch pathway inhibitors.

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Guven, S., C. Kart, E. H. Comert, H. Sal, and E. S. Guvendag Guven. "Elective repeat caesarean delivery may affect bone mineral density compared with normal vaginal delivery." European Journal of Obstetrics & Gynecology and Reproductive Biology 219 (December 2017): 131–32. http://dx.doi.org/10.1016/j.ejogrb.2017.10.005.

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Petrana, Nurul Hikmah, Ova Emilia, and Heru Pradjatmo. "Perbandingan Kejadian Retensi Urin antara Persalinan dengan Vakum Ekstraksi dan Persalinan Normal." Jurnal Kesehatan Reproduksi 3, no. 3 (2016): 188. http://dx.doi.org/10.22146/jkr.36185.

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Background: Urinary retention after vaginal delivery is a common problem with incidence 1.7% - 17.9%. Assissted vaginal delivery is one risk factor for the occurence of urinary retention.Objective: to compare urinary retention between normal vaginal delivery and assissted vaginal delivery using extraction vacum, and evaluate factors related to urinary retention.Method: The study was prospective cohort design, conducted in 3 hospitals and 2 primary health centres during 6 month period since September 2013- February 2014. Subjects were divided into two groups i.e. normal delivery and assissted delivery using extraction vacum, each 118 subjects. Events of urinary retention was assessed and also related factors were identified. Analysis used Chi-Square test, Fisher test and also logistic regression analysis.Result and Discussion: In total 236 subjects were involved, there was no difference in age and parity among the subjects. Incidence of urinary retention among extraction vacum delivery group was higher (32.2%) compare to normal delivery (11.9%). Multivariate analysis using logistic regression showed that extraction vacum (p=0.074; OR 2.71; 95% CI 1.55-4.73), baby weight (p= 0.230; OR 1.95; 95% CI 0.655.84) and perineal injury (p= 0.614; OR 1.35; 95% CI 0.41-4.36) were not significant risk factors for urinary retention. Length of labour (p=0.003; OR 3.71; 95% CI 1.55-8.86) and parity (p= 0.023; OR 2.29; 95% CI 1.2-4.66) were significant risk factors for urinary retention.Conclusion: Urinary retention is higher among vaginal delivery with extraction vacum compare to normal delivery. Length of labour and parity are external factors related to urinary retention. Keywords: Assissted vaginal delivery, extraction vacum, normal delivery, urinary retention, postpartum

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Chang, Tian-You, Chin-Ying Chung, Wei-Min Chuang, Long-Yuan Li, Long-Bin Jeng, and Wen-Lung Ma. "Durable Expression of Minicircle DNA-Liposome-Delivered Androgen Receptor cDNA in Mice with Hepatocellular Carcinoma." BioMed Research International 2014 (2014): 1–9. http://dx.doi.org/10.1155/2014/156356.

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Background. The most common gene-based cancer therapies involve the suppression of oncogenic molecules and enhancement of the expression of tumor-suppressor genes. Studies in noncancer disease animal models have shown that minicircle (MC) DNA vectors are easy to deliver and that the proteins from said MC-carrying DNA vectors are expressed over a long period of time. However, delivery of therapeutic genes via a liposome-mediated, MC DNA complex has never been tested in vascular-rich hepatocellular carcinoma (HCC). Liposome-mediated DNA delivery exhibits highin vivotransfection efficiency and minimal systemic immune response, thereby allowing for repetitive interventions. In this study, we evaluated the efficacy of delivering an MC-liposome vector containing a 3.2 kb androgen receptor (AR; HCC metastasis suppressor) cDNA into Hepatitis B Virus- (HBV-) induced HCC mouse livers.Results. Protein expression and promoter luciferase assays revealed that liposome-encapsulated MC-AR resulted in abundant functional expression of AR protein (100 kD) for up to two weeks. The AR cDNA was also successfully delivered into normal livers and diseased livers, where it was persistently expressed. In both normal livers and livers with tumors, the expression of AR was detectable for up to 60 days.Conclusion. Our results show that an MC/liposome delivery system might improve the efficacy of gene therapy in patients with HCC.

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Ohel, G., O. Fisher, and E. Megory. "Normal Delivery of the Shoulders: Active or Expectant Attitude?" Journal of Maternal-Fetal and Neonatal Medicine 3, no. 5 (1994): 200–202. http://dx.doi.org/10.3109/14767059409017276.

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Kumari, Anju, Anita Kumari, Krishna Choudhari Sinha, Ashok Sharan, Seema Kumari, and Priyanka Prasad. "Blood Pressure Variation During Different Stages of Normal Delivery." International Journal of Physiology 6, no. 1 (2018): 132. http://dx.doi.org/10.5958/2320-608x.2018.00027.6.

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Haar, P. J., Z. J. Chen, P. P. Fatouros, G. T. Gillies, F. D. Corwin, and W. C. Broaddus. "Modelling convection-enhanced delivery in normal and oedematous brain." Journal of Medical Engineering & Technology 38, no. 2 (2014): 76–84. http://dx.doi.org/10.3109/03091902.2013.837532.

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Kim, Se Hoon, In Hee Kim, and Sang Yoon Lee. "Sciatic neuropathy after normal vaginal delivery: A case report." Journal of Clinical Neuroscience 72 (February 2020): 480–82. http://dx.doi.org/10.1016/j.jocn.2019.11.031.

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