Relevant bibliographies by topics / Normalized Index of Hemolysis (NIH)

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Academic literature on the topic 'Normalized Index of Hemolysis (NIH)'

Author: Grafiati
Published: 7 June 2025
Last updated: 2 August 2025

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Journal articles on the topic "Normalized Index of Hemolysis (NIH)"

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Pradeepa, P., S. S. Murugan, Sangeetha V. Naveen, and T. S. Kumaravel. "Evaluation of Mechanical Hemolysis of Bare Metallic and Drug-Eluting Cardiovascular Stents." Indian Journal Of Science And Technology 18, no. 13 (2025): 1079–86. https://doi.org/10.17485/ijst/v18i13.645.

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Objectives: To investigate the hemolytic potential of different types of experimental cardiovascular stents [Bare Metal Stents (BMS), Sirolimus Eluting Stents (SES), and Everolimus Eluting Stents (EES)] in an in vitro study using a bovine blood circulatory model. Methods : Fresh bovine blood was circulated through the loop containing the stents, using the peristaltic pump for 6 hours at 37°C at a constant flow of 200 mL/minute. Plasma Free Hemoglobin (PFH) was measured spectrophotometrically at defined intervals. The Normalized Index of Hemolysis (NIH) and the Modified Index of Hemolysis (MIH)
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P, Pradeepa, S. Murugan S, V. Naveen Sangeetha, and S. Kumaravel T. "Evaluation of Mechanical Hemolysis of Bare Metallic and Drug-Eluting Cardiovascular Stents." Indian Journal of Science and Technology 18, no. 13 (2025): 1079–86. https://doi.org/10.17485/IJST/v18i13.645.

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Abstract <strong>Objectives:</strong>&nbsp;To investigate the hemolytic potential of different types of experimental cardiovascular stents [Bare Metal Stents (BMS), Sirolimus Eluting Stents (SES), and Everolimus Eluting Stents (EES)] in an in vitro study using a bovine blood circulatory model.&nbsp;<strong>Methods :</strong>&nbsp;Fresh bovine blood was circulated through the loop containing the stents, using the peristaltic pump for 6 hours at 37&deg;C at a constant flow of 200 mL/minute. Plasma Free Hemoglobin (PFH) was measured spectrophotometrically at defined intervals. The Normalized Inde
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3

Chan, Chris, Katrina Ki, Meili Zhang, et al. "Extracorporeal Membrane Oxygenation-Induced Hemolysis: An In Vitro Study to Appraise Causative Factors." Membranes 11, no. 5 (2021): 313. http://dx.doi.org/10.3390/membranes11050313.

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In vitro hemolysis testing is commonly used to determine hemocompatibility of ExtraCorporeal Membrane Oxygenation (ECMO). However, poor reproducibility remains a challenging problem, due to several unidentified influencing factors. The present study investigated potential factors, such as flow rates, the use of anticoagulants, and gender of blood donors, which could play a role in hemolysis. Fresh human whole blood was anticoagulated with either citrate (n = 6) or heparin (n = 12; 6 female and 6 male blood donors). Blood was then circulated for 360 min at 4 L/min or 1.5 L/min. Regardless of fl
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Oota-Ishigaki, Akiko, Takashi Yamane, Daisuke Sakota, Ryo Kosaka, Osamu Maruyama, and Masahiro Nishida. "In vitro hemocompatibility investigation for the development of low-flow centrifugal blood pumps with less platelet clogging." International Journal of Artificial Organs 45, no. 4 (2021): 431–37. http://dx.doi.org/10.1177/03913988211052570.

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Low-flow blood pumps rated under 1 L/min are emerging for new medical applications, such as hemofiltration in acute use. In those pumps, platelet adhesion and aggregation have to be carefully considered because of clogging risk in the filter part. To find an acceptable hemocompatibility that can be applied to low-flow centrifugal blood pump design, the platelet aggregation index, clogging on a micromesh filter, and the hemolysis index were investigated using a low-flow blood pump designed for hemofiltration use. We conducted circulation testing in vitro using fresh porcine blood and two centri
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WU, GUANGHUI, CHUANGYE XU, XIUJIAN LIU, et al. "HYDRAULICS AND IN VITRO HEMOLYSIS TEST OF A MAGLEV IMPLANTABLE VENTRICULAR ASSIST DEVICE." Journal of Mechanics in Medicine and Biology 17, no. 07 (2017): 1740023. http://dx.doi.org/10.1142/s0219519417400231.

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A small implantable centrifugal left ventricular assist device, the CH-VAD (CH Biomedical Inc, JiangSu, China), featuring a magnetically levitated impeller is under development. The goal of this study is to validate hydrodynamic performance and hemocompatibility of the pump through in vitro studies. The hydraulic performance was quantified experimentally by using in vitro circulation loop system, and it turned out that the pump could deliver 5[Formula: see text]L/min under a pressure of 100[Formula: see text]mmHg at a rotational speed of approximate 3400[Formula: see text]rpm. A series of in v
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Kameneva, Marina, Phil Marascalco, Trevor Snyder, and James Antaki. "VALIDITY OF NORMALIZED INDEX OF HEMOLYSIS IN PEDIATRIC MECHANICAL CIRCULATORY ASSIST DEVICES." ASAIO Journal 52, no. 2 (2006): 41A. http://dx.doi.org/10.1097/00002480-200603000-00179.

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7

Chen, Wei, and Rongliang Chen. "High-Resolution Hemodynamic Analysis of a Wearable Oxygenator Using High-Performance Computing." Journal of Physics: Conference Series 2441, no. 1 (2023): 012055. http://dx.doi.org/10.1088/1742-6596/2441/1/012055.

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Abstract In this paper, we study the hydrodynamics of a wearable oxygenator using computational fluid dynamics on a supercomputer. In this computation, the fiber bundle of the oxygenator is modeled by a porous medium model, and the incompressible Navier-Stokes equations with a K-ε turbulence model are used to model the flow in the channels. The blood flow velocity, pressure, and shear stress are carefully studied and the hemolysis index of the oxygenator NIH is calculated by using the fast three-dimensional numerical hemolysis approximation method, which is in the range 0.006 ~ 0.094 g/100L. T
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8

Song, Xinwei, Amy L. Throckmorton, Houston G. Wood, James F. Antaki, and Don B. Olsen. "Quantitative Evaluation of Blood Damage in a Centrifugal VAD by Computational Fluid Dynamics." Journal of Fluids Engineering 126, no. 3 (2004): 410–18. http://dx.doi.org/10.1115/1.1758259.

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This study explores a quantitative evaluation of blood damage that occurs in a continuous flow left ventricular assist device (LVAD) due to fluid stress. Computational fluid dynamics (CFD) analysis is used to track the shear stress history of 388 particle streaklines. The accumulation of shear and exposure time is integrated along the streaklines to evaluate the levels of blood trauma. This analysis, which includes viscous and turbulent stresses, provides a statistical estimate of possible damage to cells flowing through the pump. Since experimental data for hemolysis levels in our LVAD are no
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9

Fang, Peng, Jianjun Du, and Shunzhou Yu. "Impeller (straight blade) design variations and their influence on the performance of a centrifugal blood pump." International Journal of Artificial Organs 43, no. 12 (2020): 782–95. http://dx.doi.org/10.1177/0391398820913559.

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Introduction: The miniaturization of blood pumps has become a trend due to the advantage of easier transplantation, especially for pediatric patients. In small-scale pumps, it is much easier and more cost-efficient to manufacture the impeller with straight blades compared to spiral-profile blades. Methods: Straight-blade impeller designs with different blade angles, blade numbers, and impeller flow passage positions are evaluated using the computational fluid dynamics method. Blade angles (θ = 0°, 20°, 30°, and 40°), blade numbers ( N = 5, 6, 7, and 8), and three positions of impeller flow pas
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Bockeria, L. A., O. L. Bockeria, S. V. Selishchev, et al. "Experimental Determination of the Normalized Index of Hemolysis for the Sputnik Implantable Pediatric Rotary Blood Pump." Biomedical Engineering 50, no. 6 (2017): 416–19. http://dx.doi.org/10.1007/s10527-017-9668-9.

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Conference papers on the topic "Normalized Index of Hemolysis (NIH)"

1

Heshmat, Hooshang, James F. Walton, Michael J. Tomaszewski, and Said Jahanmir. "Magnetically Suspended Rotary Blood Pump (Keynote)." In World Tribology Congress III. ASMEDC, 2005. http://dx.doi.org/10.1115/wtc2005-63681.

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MiTiHeart™ LVAD is a rotary centrifugal blood pump with a hybrid passive/active magnetic bearing support system. It exhibits low power loss, low vibration, and high reliability under transient operating conditions. Unique features of the design include a simple and direct flow path for both main and washing blood flows, non-contact pump rotor, i.e., no rubbing surfaces, and relatively large clearances between the pump rotor and housing. The first prototype was constructed from medical grade polycarbonate. To reduce the possibility of thrombosis, the internally exposed surfaces were coated with
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