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Journal articles on the topic '(Norman Barnett)'

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Published: 4 June 2021
Last updated: 28 January 2023

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1

Badham, G., C. Hollingsworth, F. F. Fenech, H. M. Lenicker, T. G. G. Davies, A. O'Carroll, J. O. Hunter, et al. "Norman John Badham Godfrey Malcolm ("Mac") Baker Emanuel Alfred Cachia John Emsley Coates John Costello Alexander Peter Dick John Michael Faccini Thomas John Fairbank John Cedric Goligher Harold Barnett Hewitt John MacDonald ("Angus") Holmes." BMJ 316, no. 7148 (June 20, 1998): 1908. http://dx.doi.org/10.1136/bmj.316.7148.1908.

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Webb, D., R. Barnett, and L. Davies. "POS0083-PARE DRIVING IMPROVEMENT IN AXIAL SPONDYLOARTHRITIS SERVICES: THE USE OF QUALITY IMPROVEMENT APPROACHES AND TOOLS." Annals of the Rheumatic Diseases 81, Suppl 1 (May 23, 2022): 262–63. http://dx.doi.org/10.1136/annrheumdis-2022-eular.4749.

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BackgroundQuality Improvement (QI) methods have been used in healthcare since the late 1980s across a wide range of healthcare settings. However, in the UK they have not been applied widely within rheumatology including axial Spondyloarthritis (axial SpA). In 2017, the UK healthcare regulator, NICE, produced a national clinical guideline for axial SpA, but there was no mechanism to encourage uptake of its recommendations.The National Axial Spondyloarthritis Society created a programme to use QI approaches to help encourage uptake of the Guidelines and act as a catalyst for wider improvement in
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SALAH, H. H., M. DARWISH, and A. S. F. OBADA. "GENERALIZED EXCITED NEGATIVE BINOMIAL STATES OF ELECTROMAGNETIC FIELD AND SOME OF THEIR NON-CLASSICAL PROPERTIES." International Journal of Modern Physics B 17, no. 07 (March 20, 2003): 1071–86. http://dx.doi.org/10.1142/s0217979203015899.

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New states of electromagnetic field, generalized excited negative binomial states are introduced here. These states interpolate between the superposition of two excited coherent states and number states. The non-classical properties for these states are discussed, such as, second order correlation function, squeezing phenomena [normal squeezing and amplitude squared squeezing], phase properties in Pegg–Barnett formalism and the quasi-probability distribution functions (Q-function and Wigner function).
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Alexandrov, Dmitry, Leo Eisner, Umair bin Waheed, SanLinn Isma'il Ebrahim Kaka, and Stewart Alan Greenhalgh. "Normal faulting activated by hydraulic fracturing: A case study from the Barnett Shale, Fort Worth Basin." Leading Edge 39, no. 3 (March 2020): 204–11. http://dx.doi.org/10.1190/tle39030204.1.

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Surface microseismic arrays enable long-term field-scale monitoring over multiple stimulations during the life of an unconventional field. In this study, we show highly economic methods of monitoring with sparse surface arrays in the Barnett Shale and develop an alternatative method of processing to enable good vertical and horizontal resolution of located events. We show that sparse surface monitoring arrays enable not only the detection and location of high numbers of microseismic events but also source mechanism characterization. This case study illustrates how hydraulic fracturing activate
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Michael, Andreas, and Ipsita Gupta. "A Semianalytical Modeling Approach for Hydraulic Fracture Initiation and Orientation from Perforated Wells." SPE Production & Operations 36, no. 03 (January 12, 2021): 501–15. http://dx.doi.org/10.2118/204480-pa.

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Summary Accurate prediction of fracture initiation pressure and orientation is paramount to the design of a hydraulic fracture stimulation treatment and is a major factor in the treatment's eventual success. In this study, closed-form analytical approximations of the fracturing stresses are used to develop orientation criteria for relative-to-the-wellbore (longitudinal or transverse) fracture initiation from perforated wells. These criteria were assessed numerically and found to overestimate the occurrence of transverse fracture initiation, which only takes place under a narrow range of condit
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Cote, Gregory Michael, Sant P. Chawla, Melissa Amber Burgess, Katherine Anne Thornton, Robert K. Oldham, Scott H. Okuno, Karla V. Ballman, Susan Matlow, Daryl Barnett, and Steven Attia. "CBT-1 in combination with doxorubicin in patients with metastatic, unresectable sarcomas who previously progressed on doxorubicin." Journal of Clinical Oncology 37, no. 15_suppl (May 20, 2019): TPS11077. http://dx.doi.org/10.1200/jco.2019.37.15_suppl.tps11077.

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TPS11077 Background: The response rates of advanced soft tissue sarcomas (STS) to single-agent, first-line anthracycline are typically less than 25%. P-glycoprotein 1 (P-gp), a cell membrane drug efflux pump, is believed to be a resistance mechanism in STS. CBT-1 is a small molecule, orally administered, P-gp antagonist currently under clinical development. This is a multi-institutional open label phase I study of CBT-1 in combination with doxorubicin in patients with anthracycline-refractory sarcoma. The study is designed to determine a maximum tolerable dose (MTD), recommended phase II dose
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Bravo Melo, Luis Carlos, Jennyfer Portilla Yela, and José Rafael Tovar Cuevas. "Using Copula Functions to Estimate The AUC for Two Dependent Diagnostic Tests." Revista Colombiana de Estadística 43, no. 2 (July 1, 2020): 315–44. http://dx.doi.org/10.15446/rce.v43n2.80288.

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When performing validation studies on diagnostic classification procedures, one or more biomarkers are typically measured in individuals. Some of these biomarkers may provide better information; moreover, more than one biomarker may be significant and may exhibit dependence between them. This proposal intends to estimate the Area Under the Receiver Operating Characteristic Curve (AUC) for classifying individuals in a screening study. We analyze the dependence between the results of the tests by means of copula-type dependence (using FGM and Gumbel-Barnett copula functions), and studying the re
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Romero Gavilán, Serapio, and Guillermo Carrasco Aquino. "Aeromicología de locales administrativos de la Universidad Nacional de San Cristóbal de Huamanga, Ayacucho 2017." Investigación 26, no. 1 (January 1, 2018): 83–87. http://dx.doi.org/10.51440/unsch.revistainvestigacion.2018.1.62.

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Trabajo de investigación realizado con el objetivo de describir la aeromicologia de los locales administrativos de la ciudad universitaria de la Universidad Nacional de San Cristobal de Huamanga. El tipo de estudio fue no experimental con un diseño descriptivo simple, la población estuvo conformada por la totalidad de los locales administrativos, para la toma de muestra se uso el método gravimétrico de sedimentación en placa propuesto por Omeliansky, la identificación fue realizada por la observación macroscópica y microscópica de las colonias de hongos basado en la clave de Barnett (2003). Se
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9

Lemieux, Vincent. "L'articulation des réseaux sociaux." Recherches sociographiques 17, no. 2 (April 12, 2005): 247–60. http://dx.doi.org/10.7202/055716ar.

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Sous l'influence première d'un article de Barnes (1954), les études anthropologiques sur les réseaux sociaux ont ouvert une voie de recherches qui apparaît encore pleine de promesses. Il faut bien avouer, pourtant, que jusqu'à maintenant peu d'analyses fondées sur des données empiriques ont emporté la conviction. Les études de réseaux n'ont pas encore fait la preuve de leur fécondité. Il leur manque un fondement théorique, pourtant disponible dans la théorie des graphes qui est justement une théorie des réseaux, qu'ils soient sociaux ou autres. Comme l'a noté Mitchell, la jonction n'existe pas
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10

Taleghani, Arash Dahi, and Jon E. Olson. "How Natural Fractures Could Affect Hydraulic-Fracture Geometry." SPE Journal 19, no. 01 (August 18, 2013): 161–71. http://dx.doi.org/10.2118/167608-pa.

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Summary Hydraulic fracturing is recognized as the main stimulating technique to enhance recovery in tight fissured reservoirs. These fracturing treatments are often mapped by use of hypocenters of induced microseismic events. In some cases, the microseismic mapping shows asymmetry of the induced-fracture geometry with respect to the injection well. In addition, the conventional theories predict fracture propagation along a path normal to the least compressive in-situ stresses, whereas in some cases the microseismic data suggest fracture propagation parallel to the minimum compressive stress. I
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Tygel, M., J. Schleicher, and P. Hubral. "Reply by the authors to Arthur E. Barnes." GEOPHYSICS 60, no. 6 (November 1995): 1944–46. http://dx.doi.org/10.1190/1.1487021.

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We highly appreciate the useful remarks of Dr. Barnes relating our work to well‐known practical seismic processing effects. This is of particular interest as normal‐moveout (NMO) correction and post‐stack time migration are still two very important processing steps. Most exploration geophysicists know about the significance of pulse distortions known as “NM0 stretch” and “frequency shifting due to zero‐offset time migration.” As a result of the discussion of Dr. Barnes, it should now be possible to better appreciate the importance of our very general formulas (27) describing the pulse distorti
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12

Kassab, Kalthoum. "Transfer of Learning Outcomes from an English-for-Specific-Academic-Writing Course to Subject-Specific Courses." Journal of English Language Teaching and Applied Linguistics 3, no. 7 (June 30, 2021): 40–59. http://dx.doi.org/10.32996/jeltal.2021.3.7.4.

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This study investigated the transfer of ten learning outcomes from an ESAP writing course to subject-specific courses. It was a longitudinal study carried over one academic year. It followed 40 undergraduate students of English under normal classroom conditions. A mixed-methods approach was used. It included analysis of students’ written exams from four subjects, student semi-structured interviews, and a student questionnaire. Elements from Barnett and Ceci’s (2002) transfer taxonomy were also used. They helped classify the targeted learning outcomes in terms of specificity/generality and help
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13

Verma, Surendra P., Lorena Díaz-González, Mauricio Rosales-Rivera, and Alfredo Quiroz-Ruiz. "Comparative Performance of Four Single Extreme Outlier Discordancy Tests from Monte Carlo Simulations." Scientific World Journal 2014 (2014): 1–27. http://dx.doi.org/10.1155/2014/746451.

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Using highly precise and accurate Monte Carlo simulations of 20,000,000 replications and 102 independent simulation experiments with extremely low simulation errors and total uncertainties, we evaluated the performance of four single outlier discordancy tests (Grubbs test N2, Dixon test N8, skewness test N14, and kurtosis test N15) for normal samples of sizes 5 to 20. Statistical contaminations of a single observation resulting from parameters calledδfrom ±0.1 up to ±20 for modeling the slippage of central tendency orεfrom ±1.1 up to ±200 for slippage of dispersion, as well as no contamination
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14

Srinivasan, A., and G. Geetharamani. "Linear Programming Problem with Interval Type 2 Fuzzy Coefficients and an Interpretation for Its Constraints." Journal of Applied Mathematics 2016 (2016): 1–11. http://dx.doi.org/10.1155/2016/8496812.

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Interval type 2 fuzzy numbers are a special kind of type 2 fuzzy numbers. These numbers can be described by triangular and trapezoidal shapes. In this paper, first, perfectly normal interval type 2 trapezoidal fuzzy numbers with their left-hand and right-hand spreads and their core have been introduced, which are normal and convex; then a new type of fuzzy arithmetic operations for perfectly normal interval type 2 trapezoidal fuzzy numbers has been proposed based on the extension principle of normal type 1 trapezoidal fuzzy numbers. Moreover, in this proposal, linear programming problems with
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15

Deaville, E. R., and D. L. Givens. "Factors affecting the prediction of organic matter Digestibility of grass silage by near infrared reflectance spectroscopy." Proceedings of the British Society of Animal Production (1972) 1994 (March 1994): 73. http://dx.doi.org/10.1017/s0308229600026209.

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Earlier studies (Barber et al., 1990) showed the superiority of near infrared reflectance spectroscopy (NIRS) for predicting the organic matter digestibility (OMD) in vivo of grass silage over fibre and in vitro procedures. However, during routine application occasional erroneous values were predicted for which there were no obvious reasons. Baker and Barnes (1990) reported that the likely sources of the problems contributing to the errors were instrumental and environmental noise, sample particle size effects and variable moisture content of the samples. These authors also reported that stand
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16

Kuang, Wenhuan, Mark Zoback, and Jie Zhang. "Estimating geomechanical parameters from microseismic plane focal mechanisms recorded during multistage hydraulic fracturing." GEOPHYSICS 82, no. 1 (January 1, 2017): KS1—KS11. http://dx.doi.org/10.1190/geo2015-0691.1.

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We extend a full-waveform modeling method to invert source focal-plane mechanisms for microseismic data recorded with dual-borehole seismic arrays. Combining inverted focal-plane mechanisms with geomechanics knowledge, we map the pore pressure distribution in the reservoir. Determining focal mechanisms for microseismic events is challenging due to poor geometry coverage. We use the P-wave polarities, the P- and S-wave similarities, the SV/P amplitude ratio, and the SH/P amplitude ratio to invert the focal-plane mechanisms. A synthetic study proves that this method can effectively resolve focal
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17

Focardi, P., B. Kelm, and G. G. C. Palumbo. "Seyfert Galaxies and Their Environment." Symposium - International Astronomical Union 186 (1999): 355. http://dx.doi.org/10.1017/s0074180900113026.

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The role played by environment on nuclear activity in galaxies is not clear and largely debated (see e.g. Barnes & Hernquist 1992, Kelm 1996). To overcome statistical uncertainties, environment properties of two large samples of Seyfert galaxies (Sy 1 and Sy 2 have been kept separated) have been computed and compared with equivalent size “normal galaxy” sample ones. Seyfert samples have been extracted from the Veron & Veron catalogue (Veron & Veron 1996), whilst “normal galaxies” have been randomly extracted from ZCAT (Huchra 1993). The samples are limited in cz ([1500–9500] km/sec
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18

Stein, Ivar S., Michaela S. Donaldson, and Johannes W. Hell. "CaMKII binding to GluN2B is important for massed spatial learning in the Morris water maze." F1000Research 3 (August 12, 2014): 193. http://dx.doi.org/10.12688/f1000research.4660.1.

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Learning and memory as well as long-term potentiation (LTP) depend on Ca2+ influx through the NMDA-type glutamate receptor (NMDAR) and the resulting activation of the Ca2+ and calmodulin-dependent protein kinase (CaMKII). Ca2+ influx via the NMDAR triggers CaMKII binding to the NMDAR for enhanced CaMKII accumulation at post-synaptic sites that experience heightened activity as occurring during LTP. Previously, we generated knock-in (KI) mice in which we replaced two residues in the NMDAR GluN2B subunit to impair CaMKII binding to GluN2B. Various forms of LTP at the Schaffer collateral synapses
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19

Alexander, Rosemary, and Adrian White. "Acupuncture in a Rheumatology Clinic." Acupuncture in Medicine 18, no. 2 (December 2000): 100–103. http://dx.doi.org/10.1136/aim.18.2.100.

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An acupuncture clinic was established, for a limited period, within a rheumatology department of Barnet and Chase Farm Hospital Trust. Courses of six to eight sessions of traditional and trigger-point acupuncture were offered for a specified range of conditions. Pain and use of analgesics were measured routinely. A prospective observational study is presented of the outcome for a series of 41 patients, who had a mean age of 57 years and pain duration of 3 years. The mean score for daytime pain fell from 6.8 (SD 1.2) to 4.9 (2.5) points which is highly significant (p < 0.001). A total of 30
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20

Garcia, Delia M., Hamid R. Latifi, Joseph R. Simpson, and Selwyn Picker. "Astrocytomas of the cerebellum in children." Journal of Neurosurgery 71, no. 5 (November 1989): 661–64. http://dx.doi.org/10.3171/jns.1989.71.5.0661.

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✓ Between 1928 and 1980, 84 children (aged 19 years or younger) with an astrocytoma of the cerebellum were managed at Washington University Medical Center-Barnes Hospital. Fifty-eight children were treated with surgery only and 26 received surgery and postoperative irradiation. The 5-, 10-, and 25-year actuarial disease-free survival rates for the entire group were 92%, 88%, and 88%, respectively. Age at diagnosis and extent of surgery were prognostic factors, but no correlation with survival times was found for gross appearance of the tumor or postoperative irradiation. Posttreatment neurolog
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Medeiros, Jordânia Xavier de, Ana Lícia Patriota Feliciano, Jamile Erica de Medeiros, Helder Henrique Duarte Santos, and Valderez Pontes Matos. "MORFOLOGIA DA GERMINAÇÃO DE SEMENTES DE Senna cana (Nees & Mart.) H.S. Irwin & Barneby." Nativa 7, no. 6 (November 11, 2019): 784. http://dx.doi.org/10.31413/nativa.v7i6.8626.

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O objetivo do estudo foi descrever a morfologia da germinação de plântulas normais de Senna cana (Nees & Mart.) H. S. Irwin & Barneby e, descrever as plântulas anormais. A coleta das sementes foi realizada no Parque Nacional Vale do Catimbau, Buíque - PE. As sementes foram escarificadas, desinfestadas e lavadas com água deionizada. Foram utilizadas quatro repetições de 25 sementes, semeadas sobre papel toalha e postas para germinar em B.O.D a 20-30ºC. A emissão da radícula ocorreu no terceiro dia após semeadura, coloração bege amarelada, tenra, cilíndrica, com pelos radiculares. Do 7º
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Djera, Adelvia Tamu Ina Pay. "ALIENASI ISRAEL UTARA." Pute Waya : Sociology of Religion Journal 1, no. 01 (March 6, 2021): 24–39. http://dx.doi.org/10.51667/pwjsa.v1i01.217.

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Masyarakat sebagai elemen dasar dari peradaban manusia, sejatinya terbentuk dalam berbagai upaya dan interaksi sosial. Interaksi yang terjalin disebabkan oleh berbagai aspek, hubungan biologis, lokasi tempat tinggal, suku, pemahaman ideologi yang sama termasuk usaha untuk mencapai tujuan bersama melalui kesepakatan-kesepakatan sosial tertentu yang mengikat. Tulisan ini bertujuan untuk mengkaji fenomena ini dengan teori Karl Marx sebagai acuan dari munculnya konflik dalam kehidupan Bangsa Israel, lebih lanjut didukung oleh beberapa teori sosial lainnya. Adapun tulisan ini menggunakan metode her
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Parfait, Bouvourné, Beppe Galba Jean, Ponka Roger, Ngatanko Abaissou Hervé Hervé, Kamleu Kwingwa Balbine, Camdi Woumitna Guillaume, Guedang Nyayi Simon Desire, Damo Kamda Jorelle Linda, Kenko Djoumessie Léa Blondelle, and Sotoing Taiwe Germain. "Antioxidant and Anticholinesterase Properties of the Aqueous Extract of Balanites aegyptiaca L. Delile Fruit Pulp on Monosodium Glutamate-Induced Excitotoxicity in Swiss Mice." Evidence-Based Complementary and Alternative Medicine 2022 (April 11, 2022): 1–15. http://dx.doi.org/10.1155/2022/7576132.

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Balanites aegyptiaca L. Delile (B. aegyptiaca) is used in traditional medicine for the treatment of memory impairment. This work aims to evaluate the antioxidant and anticholinesterase potential of BA fruit pulp extract on excitotoxicity induced by monosodium glutamate (MSG). MSG was administered 30 minutes after treatment with B. aegyptiaca aqueous fruit pulp extract (50, 125, 250, and 500 mg/kg) and vitamin C (100 mg/kg) for 30 days. The negative control group received only MSG, while the control group was given distilled water daily. Behavioral tests parameters (using the novel object recog
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Makaryus, Rany, Hedok Lee, John Robinson, Grigori Enikolopov, and Helene Benveniste. "Noninvasive Tracking of Anesthesia Neurotoxicity in the Developing Rodent Brain." Anesthesiology 129, no. 1 (July 1, 2018): 118–30. http://dx.doi.org/10.1097/aln.0000000000002229.

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Abstract Background Potential deleterious effect of multiple anesthesia exposures on the developing brain remains a clinical concern. We hypothesized that multiple neonatal anesthesia exposures are more detrimental to brain maturation than an equivalent single exposure, with more pronounced long-term behavioral consequences. We designed a translational approach using proton magnetic resonance spectroscopy in rodents, noninvasively tracking the neuronal marker N-acetyl-aspartate, in addition to tracking behavioral outcomes. Methods Trajectories of N-acetyl-aspartate in anesthesia naïve rats (n
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25

Little, Mark, Peter Pereira, and Jamie Seymour. "Differences in Cardiac Effects of Venoms from Tentacles and the Bell of Live Carukia barnesi: Using Non-Invasive Pulse Wave Doppler." Toxins 13, no. 1 (December 29, 2020): 19. http://dx.doi.org/10.3390/toxins13010019.

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Carukia barnesi was the first in an expanding list of cubozoan jellyfish whose sting was identified as causing Irukandji syndrome. Nematocysts present on both the bell and tentacles are known to produce localised stings, though their individual roles in Irukandji syndrome have remained speculative. This research examines differences through venom profiling and pulse wave Doppler in a murine model. The latter demonstrates marked measurable differences in cardiac parameters. The venom from tentacles (CBVt) resulted in cardiac decompensation and death in all mice at a mean of 40 min (95% CL: ± 11
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Silva, Aparecida Leonir da, Daniel Teixeira Pinheiro, Eduardo Euclydes de Lima e. Borges, Laércio Junio da Silva, and Denise Cunha Fernandes dos Santos Dias. "Salinity tolerance in Senna macranthera (DC. ex Collad.) H. S. Irwin & Barneby seeds with sodium nitroprusside (SNP) promoted by cyanide." Journal of Seed Science 40, no. 3 (September 2018): 323–30. http://dx.doi.org/10.1590/2317-1545v40n3198495.

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Abstract: Studies show the positive effect of the nitric oxide donor in the seed germination process. However, there are no precise reports about which compound present in sodium nitroprusside would cause these effects in seeds under salt stress. The aim of this study was to evaluate the effects of SNP on germination of Senna macranthera seeds under salt stress. The osmotic potentials of -0.3, -0.4, and -0.5 MPa of NaCl were used, as well as the concentration of 100 μM of sodium nitroprusside, inactive sodium nitroprusside, and ferrocyanide. The sodium nitroprusside in germination was applied
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Ho, Herbert L., Charles L. Bauer, Subhash Mahajan, David E. Laughlin, and Arthur G. Milnes. "Microstructural characterization of ordered nickel silicide structures grown on (111) nickel silicide films." Journal of Materials Research 11, no. 4 (April 1996): 904–11. http://dx.doi.org/10.1557/jmr.1996.0112.

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The formation processes of epitaxial nickel silicides, resulting from the interaction of nickel silicide films (10 nm–100 nm) on (111) silicon (Si) substrates after furnace annealing, have been studied using transmission electron microscopy (TEM) and x-ray diffraction (XRD) techniques. The formation of type-A epitaxial grains (i.e., grown with the same orientation of the underlying Si substrate) and type-B epitaxial grains (i.e., rotated by 180± around the surface normal) in “thick” epitaxial films (i.e., greater than 35 nm) is proposed to be linked to the formation of a fluorite-based CuPt (L
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McCreadie, R. G., R. Thara, S. Kamath, R. Padmavathy, S. Latha, N. Mathrubootham, and M. S. Menon. "Abnormal Movements in Never-Medicated Indian Patients with Schizophrenia." British Journal of Psychiatry 168, no. 2 (February 1996): 221–26. http://dx.doi.org/10.1192/bjp.168.2.221.

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BackgroundHistorical records suggest dyskinesia was observed in severely ill institutionalised patients with schizophrenia in the pre-neuroleptic era More recent work has not found dyskinesia in never-medicated younger and middle aged patients. The present study complements this recent work and avoids the confounders of severity of illness and institutionalism by examining elderly patients in a wide variety of community settings.MethodMovement disorders were examined in 308 elderly individuals in Madras, India, using the Abnormal Involuntary Movements Scale, the Simpson and Angus Parkinsonism
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29

Nanou, Evanthia, Todd Scheuer, and William A. Catterall. "Calcium sensor regulation of the CaV2.1 Ca2+ channel contributes to long-term potentiation and spatial learning." Proceedings of the National Academy of Sciences 113, no. 46 (October 31, 2016): 13209–14. http://dx.doi.org/10.1073/pnas.1616206113.

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Many forms of short-term synaptic plasticity rely on regulation of presynaptic voltage-gated Ca2+ type 2.1 (CaV2.1) channels. However, the contribution of regulation of CaV2.1 channels to other forms of neuroplasticity and to learning and memory are not known. Here we have studied mice with a mutation (IM-AA) that disrupts regulation of CaV2.1 channels by calmodulin and related calcium sensor proteins. Surprisingly, we find that long-term potentiation (LTP) of synaptic transmission at the Schaffer collateral-CA1 synapse in the hippocampus is substantially weakened, even though this form of syn
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Mima, Yurina, Nobuo Izumo, Jiun-Rong Chen, Suh-Ching Yang, Megumi Furukawa, and Yasuo Watanabe. "Effects of Coriandrum sativum Seed Extract on Aging-Induced Memory Impairment in Samp8 Mice." Nutrients 12, no. 2 (February 11, 2020): 455. http://dx.doi.org/10.3390/nu12020455.

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The purpose of this study was to investigate whether or not Coriandrum sativum seed extract (CSSE) can ameliorate memory impairment in senescence-accelerated mouse-prone 8 (SAMP8) mice. Sixteen 10-week-old male SAMP8 mice were divided into two groups, which were orally administrated water (SAMP8(−)) or CSSE (200 mg/kg/day; SAMP8(+)). Eight 10-week-old male Institute of Cancer Research (ICR) mice were used as a normal control group and were also orally administrated water. The mean escape time in the Barnes maze test of SAMP8(−) mice was significantly longer than that of ICR mice. However, SAMP
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Patel, Swetal, Francis Oyebanji та Kurt J. Marfurt. "A method to compensate for migration stretch to improve the resolution of amplitude variation with offset, S-impedance (ZS), and density (ρ)". Interpretation 8, № 4 (31 серпня 2020): T687—T699. http://dx.doi.org/10.1190/int-2019-0226.1.

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Because of their improved leverage against ground roll and multiples, as well as the ability to estimate azimuthal anisotropy, wide-azimuth 3D seismic surveys routinely now are acquired over most resource plays. For a relatively shallow target, most of these surveys can be considered to be long offset as well, containing incident angles up to 45°. Unfortunately, effective use of the far-offset data often is compromised by noise and normal moveout (NMO) (or, more accurately, prestack migration) stretch. The conventional NMO correction is well-known to decrease the frequency content and distort
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Heck, Ralph Leal. "Uma comparação entre a interpretação de Kretzmann sobre a correção dos nomes no Crátilo de Platão e as teorias do significado de David Lewis." Nuntius Antiquus 12, no. 2 (January 26, 2017): 225–61. http://dx.doi.org/10.17851/1983-3636.12.2.225-261.

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O presente artigo tem o objetivo de propor a continuidade dos temas tratados no diálogo Crátilo de Platão pelo filósofo analítico David Lewis, a partir da associação entre suas teorias do significado e as teorias da linguagem contidas na obra platônica, em especial, aquelas defendidas pelo personagem Sócrates, deduzidas assim, pela leitura de Norman Kretzmann e revisadas segundo algumas críticas direcionadas ao intérprete, de modo a provar a semelhança de escopo e dimensão linguística entre a teoria filosófica da linguagem em Platão e a teoria filosófica da linguagem em Lewis. Para executar es
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33

Carrillo-Parra, Artemio, Rahim Foroughbakhch-Pournavab, and Verónica Bustamante-García. "CALIDAD DEL CARBÓN DE Prosopis laevigata (Humb. & Bonpl. ex Willd.) M.C. Johnst. y Ebenopsis ebano (Berland.) Barneby & J.W. Grimes ELABORADO EN HORNO TIPO FOSA." Revista Mexicana de Ciencias Forestales 4, no. 17 (September 27, 2018): 62–71. http://dx.doi.org/10.29298/rmcf.v4i17.421.

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 La biomasa se utiliza para la generación de calor y la preparación de alimentos por aproximadamente dos mil millones de personas en el mundo. En el área metropolitana de Monterrey, Nuevo León el consumo de carbón vegetal con fines recreativos tiene una demanda de 5 500 t mes-1. En México su comercialización se basa en conocimientos empíricos: especie, duración del encendido, producción de chispas y cenizas. Sin embargo, para su exportación se deben cumplir esquemas de calidad. Por lo anterior, en la presente investigación se comparó el rendimiento y calidad de
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34

So, Simon W., Kendra M. Fleming, Cayla M. Duffy, Joshua P. Nixon, David A. Bernlohr, and Tammy A. Butterick. "Microglial FABP4-UCP2 Axis Modulates Neuroinflammation and Cognitive Decline in Obese Mice." International Journal of Molecular Sciences 23, no. 8 (April 14, 2022): 4354. http://dx.doi.org/10.3390/ijms23084354.

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The microglial fatty-acid-binding protein 4-uncoupling protein 2 (FABP4-UCP2) axis is a key regulator of neuroinflammation in high-fat-diet (HFD)-fed animals, indicating a role for FABP4 in brain immune response. We hypothesized that the FABP4-UCP2 axis is involved in regulating diet-induced cognitive decline. We tested cognitive function in mice lacking microglial FABP4 (AKO mice). Fifteen-week-old male AKO and wild-type (WT) mice were maintained on 60% HFD or normal chow (NC) for 12 weeks. Body composition was measured using EchoMRI. Locomotor activity, working memory, and spatial memory wer
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35

Quandt, P., and M. D. R. Cejas Méndez. "Pseudoakathisia in a patient with clotiapine abuse: Report of a case." European Psychiatry 33, S1 (March 2016): S550. http://dx.doi.org/10.1016/j.eurpsy.2016.01.2030.

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IntroductionObjective symptoms of akathisia in the absence of subjective symptoms is known as pseudoakathisia, more often diagnosed in older patients with long-term antipsychotic treatment.ObjectiveTo describe a case of pseudoakathisia in a patient with clotiapine abuse.AimsPseudoakathisia management.MethodsX is a 47-year-old male with chronic insomnia treated with clotiapine 40 mg/day for four years. He admits abusive neuroleptic consumption in the past eight months (160 mg/day), without any psychiatric control for years. In recent months he has experienced different organic complications, re
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36

Ahring, Kirsten K., Frederik Dagnæs-Hansen, Annemarie Brüel, Mette Christensen, Erik Jensen, Thomas G. Jensen, Mogens Johannsen, et al. "The effect of casein glycomacropeptide versus free synthetic amino acids for early treatment of phenylketonuria in a mice model." PLOS ONE 17, no. 1 (January 11, 2022): e0261150. http://dx.doi.org/10.1371/journal.pone.0261150.

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Introduction Management of phenylketonuria (PKU) is mainly achieved through dietary control with limited intake of phenylalanine (Phe) from food, supplemented with low protein (LP) food and a mixture of free synthetic (FS) amino acids (AA) (FSAA). Casein glycomacropeptide (CGMP) is a natural peptide released in whey during cheese making by the action of the enzyme chymosin. Because CGMP in its pure form does not contain Phe, it is nutritionally suitable as a supplement in the diet for PKU when enriched with specific AAs. Lacprodan® CGMP-20 (= CGMP) used in this study contained only trace amoun
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Ohiemi Amedu, Nathaniel, and Michael Olim Obu. "Atrazine-Induced Hippocampal Degeneration and Behavioral Deficits in Wistar Rats: Mitigative Role of Avocado Oil." Iranian Journal of Toxicology 16, no. 3 (July 15, 2022): 211–20. http://dx.doi.org/10.32598/ijt.16.3.949.2.

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Background: Glutamate is essential to learning and memory as an excitatory neurotransmitter. This study evaluated the atrazine effect on the hippocampus and examined the mitigative role of avocado oil against the neuronal degeneration and behavioral deficits in Wistar rats. Methods: Fifty adult male Wistar rats were divided into four groups of ten. Group 1 (controls) received 0.5 ml distilled water; group 2 received atrazine (215 mg/kg/d); group 3 received avocado oil (1 ml/ 250 g/d); group 4 received avocado oil (1 ml/ 250 g/d) 60 minutes before atrazine. Treatments were given by oral gavage
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38

Wang-Gillam, Andrea, Albert C. Lockhart, Benjamin R. Tan, Rama Suresh, Preet Paul Singh, Kian-Huat Lim, Katrina Pedersen, Manik A. Amin, William G. Hawkins, and David G. DeNardo. "Phase I study of defactinib combined with pembrolizumab and gemcitabine in advanced cancer." Journal of Clinical Oncology 35, no. 4_suppl (February 1, 2017): TPS505. http://dx.doi.org/10.1200/jco.2017.35.4_suppl.tps505.

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TPS505 Background: Focal adhesion kinase (FAK) is consistently hyperactivated in pancreatic ductal adenocarcinoma (PDAC), and FAK signaling is a key driver in forming its fibrotic and proinflammatory tumor microenvironment. Inhibition of FAK signaling leads to significant reduction of pancreatic tumor growth in animal models. Indeed, tumors treated with FAK inhibitors displayed markedly reduced tumor fibrosis and decreased immunosuppressive myeloid cells. Furthermore, our preclinical work has demonstrated that FAK- and PD-1 inhibitors elicit significant tumor regression, and the maximal respon
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Yi, Xin, Jia yong Liu, Jie Dai, Jun Guo, Cong ying Wu, Lu Si, Lili Mao, and Zhong Hui Qi. "Characterization of mechano-microenvironment of acral melanoma and its potential impact on tumor cell invasion." Journal of Clinical Oncology 37, no. 15_suppl (May 20, 2019): e21062-e21062. http://dx.doi.org/10.1200/jco.2019.37.15_suppl.e21062.

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e21062 Background: Acral melanoma is the main subtype in Asia, and tends to be insensitive to conventional and novel therapies compared with cutaneous melanomas. It has been proved that biomechanical alterations inside the tumor microenvironment significantly affect tumor progression in breast, pancreatic and other cancers(Hepatology. 2016 July ; 64(1): 261–275; Cold Spring Harbor Symposia on Quantitative Biology, Volume LXXXI) . Hence, we hypothesized that the biomechanical microenvironment plays critical roles in proliferation and invasion in acral melanoma. In this study, the main purpose i
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Siqueira, Ana Cristina O., and Benson Honig. "Entrepreneurs’ ingenuity and self-imposed ethical constraints: creating sustainability-oriented new ventures and knowledge." Journal of Knowledge Management 23, no. 10 (December 9, 2019): 1965–83. http://dx.doi.org/10.1108/jkm-11-2018-0707.

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Purpose Ingenuity can be viewed as the use of creativity to develop innovation within constraints. The authors investigate how entrepreneurial ingenuity is enhanced by self-imposed ethical constraints, by using a case study of sustainability-driven technology enterprises in an emerging economy. The authors find that self-imposed ethical constraints can enhance entrepreneurial ingenuity because they encourage entrepreneurs to solve more complex problems as a result of considering the impact of the business on a more diverse set of stakeholders. The aim of this study is to show that while additi
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Barnett, Burton Earle, Xinxin Wang, David L. Hermanson, Yening Tan, Eric M. Osertag, and Devon J. Shedlock. "Development of Novel Non-Immunoglobulin Centyrin-Based Cars (CARTyrins) Targeting Human Bcma." Blood 128, no. 22 (December 2, 2016): 4557. http://dx.doi.org/10.1182/blood.v128.22.4557.4557.

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Abstract Chimeric-antigen receptor (CAR)-T cell immunotherapy is a promising type of cancer therapy and substantial progress has been made in developing adoptive T cell approaches for B cell malignancies. B cell maturation antigen (BCMA) is an attractive target for patients with multiple myeloma (MM) due to its high level of expression on tumor cells and restricted expression on normal tissues. Traditionally, the antigen-binding domain of a CAR is a single chain variable fragment (scFv) comprised of heavy chain (HC) and light chain (LC) variable fragments joined by a flexible linker that has b
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Anagnostis, Panagiotis, Rodis Paparodis, Julia Bosdou, Christina Bothou, Dimitrios G. Goulis, Djuro P. Macut, Andrea Elizabeth Dunaif, and Sarantis Livadas. "The Major Impact of Obesity on the Development of Type 2 Diabetes (T2D) in Women With PCOS: A Systematic Review and Meta-Analysis of Observational Studies." Journal of the Endocrine Society 5, Supplement_1 (May 1, 2021): A746—A747. http://dx.doi.org/10.1210/jendso/bvab048.1517.

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Abstract Background/Aims: Polycystic ovary syndrome (PCOS) is associated with disordered carbohydrate metabolism and an increased risk for T2D. However, there are limited data on the magnitude of this risk. Furthermore, 50-80% of women with PCOS are obese and obesity is known to have a synergistic deleterious effect on glucose tolerance in affected women. We systematically reviewed the literature regarding the association between PCOS, obesity and T2D risk. Methods: A comprehensive search was conducted in PubMed, CENTRAL and Scopus databases. Data are expressed as relative risk (RR) with 95% c
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43

Beltran de Heredia Ruiz, Ignasi. "Personal interino del sector público y nombramientos abusivos a la luz del asunto "Sánchez Ruiz/Fernández Álvarez"." RVGP 18, no. 18 (June 1, 2020): 8–37. http://dx.doi.org/10.47623/ivap-rvgp.18.2020.01.

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Laburpena: Laburpena: Aldi baterako kontratazioan gehiegikeriari aurre egiteko Europar Batasuneko eta barneko neurriek ez dute sistema bateratu bat osatu, logika estratifikatu bati erantzun diote. Arkitektura horri esker, barne-zuzenbideak Europako gidalerroetatik eta horiei eusteko tresnetatik aldendu da. Horren ondorioz (beste arrazoi batzuekin batera), behin-behinekotasun tasa onartezinak sortu dira eta fenomeno patologiko eta kroniko bihurtu da. Azterlan honek Europar Batasuneko Justizia Auzitegiaren (EBJA) doktrina aztertzen du, «Sánchez Ruiz/Fernández Álvarez» gai garrantzitsuraino, bai
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44

Lopez, David Cobeta, Kerstin Klingner, Marie Carkill, Robert Nunan, Anya Avrutskaya, Paula Miliani de Marval, Amber Blackwell, et al. "Abstract 5612: A streamlined workflow for preclinical assessment of monoclonal antibody therapies: A case study." Cancer Research 82, no. 12_Supplement (June 15, 2022): 5612. http://dx.doi.org/10.1158/1538-7445.am2022-5612.

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Abstract Monoclonal antibody (mAb) therapies have become the dominant product class within the biopharmaceutical industry mainly due to their intrinsic capacity to bind endogenous immune receptors and targeted antigens. In fact, this kind of therapeutic agent accounts for one fifth of the FDA’s new drug approvals each year. In addition, their stability and specificity make them the ideal scaffold to develop more complex and efficacious drug modalities such as bispecific antibodies and antibody-drug conjugates. However, in order to advance mAb therapies to the clinic, there are a number of para
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Kidwell, Adam P., Nidhi Bhatt, Mindy L. Simpson, and Lisa N. Boggio. "Dosing Factor in Pediatric and Adult Hemophilia Patients Using Ideal Body Weight Versus actual Body Weight." Blood 128, no. 22 (December 2, 2016): 4958. http://dx.doi.org/10.1182/blood.v128.22.4958.4958.

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Abstract Background: Hemophilia A (factor VIII deficiency) and hemophilia B (factor IX deficiency) are X-linked inherited bleeding disorders which cause recurrent bleeding into the joints leading to significant morbidity. The cornerstone of management is treatment of bleeding with infusions of factor concentrate.(Barnes et al 2013) Adoption of prophylactic treatment with regular factor infusions has dramatically improved life expectancy and quality of life in patients with hemophilia. (Manco-Johnson et al 2007) Dosing of factor replacement therapy is currently based on actual body weight (AW).
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How, Joan, Stephen T. Oh, and Kathryn M. Trinkaus. "Distinct Clinical, Laboratory, and Molecular Features of Myeloproliferative Neoplasm Patients Presenting with Splanchnic Vein Thrombosis." Blood 128, no. 22 (December 2, 2016): 3121. http://dx.doi.org/10.1182/blood.v128.22.3121.3121.

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Abstract BACKGROUND: Myeloproliferative neoplasms (MPN), including polycythemia vera (PV), essential thrombocythemia (ET), and primary meylofibrosis (PMF), are frequently associated with splanchnic vein thromboses (SVT). Risk factors for SVT in MPN patients differ from risk factors for all-cause thrombosis. This is likely due to differing disease mechanisms at play, and suggest a separate disease phenotype for MPN/SVT patients. While several studies have characterized the features of MPN patients with SVT, a direct comparison of MPN/SVT versus all MPN patients has been lacking. METHODS: We per
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Rahardjo, Budi, Fachrul Rozie, and Jessika Maulina. "Parents’ Role in Children's Learning During and After the Covid-19 Pandemic." JPUD - Jurnal Pendidikan Usia Dini 16, no. 1 (April 30, 2022): 69–84. http://dx.doi.org/10.21009/jpud.161.05.

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When children only see their friends in little squares via Google Meet or Zoom, can teachers really address concepts like the importance of teamwork or how to manage conflict? This is a learning phenomenon during the COVID-19 pandemic and the era after it. This study aims to see the role of parents as children's learning companions in terms of mentors and motivators when online education takes place. This research using photovoice within phenomenological methodology and have been doing with thematic analysis and collecting data through interviews and observations. The participants were eight p
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Martinez, Alexandra, Jacques Malavieille, Serge Lallemand, and Jean-Yves Collot. "Strain partitioning in an accretionary wedge, in oblique convergence : analogue modelling." Bulletin de la Société Géologique de France 173, no. 1 (January 1, 2002): 17–24. http://dx.doi.org/10.2113/173.1.17.

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Abstract In subduction zones undergoing oblique convergence, strain partitioning is often expressed by an important deformation inducing strike-slip faulting. In accretionary wedges, parameters such as obliquity of the convergence and friction at the bottom of the wedge play an important role in the strain partitioning. The impact of these parameters is studied using sandbox experiments. Two backstop geometries have been designed to account for different geological settings. These experiments show that the wedge taper remains constant and close to αcoulomb for variable obliquities. Measurement
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Bhandari, Sudhir, Ajit Singh Shaktawat, Bhoopendra Patel, Amitabh Dube, Shivankan Kakkar, Amit Tak, Jitendra Gupta, and Govind Rankawat. "The sequel to COVID-19: the antithesis to life." Journal of Ideas in Health 3, Special1 (October 1, 2020): 205–12. http://dx.doi.org/10.47108/jidhealth.vol3.issspecial1.69.

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The pandemic of COVID-19 has afflicted every individual and has initiated a cascade of directly or indirectly involved events in precipitating mental health issues. The human species is a wanderer and hunter-gatherer by nature, and physical social distancing and nationwide lockdown have confined an individual to physical isolation. The present review article was conceived to address psychosocial and other issues and their aetiology related to the current pandemic of COVID-19. The elderly age group has most suffered the wrath of SARS-CoV-2, and social isolation as a preventive measure may furth
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50

Bubshait, Abdulrahman, and Birendra Jha. "Revisiting 2013-2014 Azle seismicity to understand the role of Barnett production on stress propagation and fault stability." GEOPHYSICS, May 6, 2022, 1–79. http://dx.doi.org/10.1190/geo2021-0317.1.

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Propagation of production- and injection-induced stresses from reservoir layers to basement faults is not well understood, especially in reservoirs with hydraulically segregated production and injection units situated across low-permeability structural or stratigraphic boundaries. This is one of the challenges in understanding the 2013–2014 Azle-Reno earthquake sequence (maximum magnitude M w 3.8) in the Fort Worth Basin of Texas, which occurred after several billion cubic meters of gas and several million cubic meters of brine were produced from the Barnett Shale and several million cubic met
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