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Relevant bibliographies by topics / Normetanephrine

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Academic literature on the topic 'Normetanephrine'

Author: Grafiati

Published: 4 June 2021

Last updated: 11 February 2022

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Journal articles on the topic "Normetanephrine"

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Iinuma, K., I. Ikeda, T. Ogihara, K. Hashizume, K. Kurata, and Y. Kumahara. "Radioimmunoassay of metanephrine and normetanephrine for diagnosis of pheochromocytoma." Clinical Chemistry 32, no. 10 (1986): 1879–83. http://dx.doi.org/10.1093/clinchem/32.10.1879.

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Abstract Sensitive and specific radioimmunoassays of metanephrine and normetanephrine were developed by use of 125I-labeled synephrine and specific metanephrine antibody, and 125I-labeled octopamine and specific normetanephrine antibody. Specific antibody for both metanephrine and normetanephrine was raised in rabbits by immunization with bovine serum albumin conjugated with the corresponding hapten, prepared by the method of Grota and Brown (Endocrinology 1976;98:615). The detection limits of the metanephrine and the normetanephrine radioimmunoassays were 2 and 6 pg/tube, respectively. Mean p

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Cho, Yoon Y., Young N. Kim, Jung-Han Kim, Byong C. Jeong, Soo-Youn Lee, and Jae H. Kim. "Different values of urinary fractionated metanephrines after unilateral adrenalectomy for pheochromocytoma according to time intervals after surgery." Annals of Clinical Biochemistry: International Journal of Laboratory Medicine 54, no. 1 (2016): 165–69. http://dx.doi.org/10.1177/0004563215620822.

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Background After adrenalectomy, urinary fractionated metanephrine concentrations are expected to be reduced. However, there are few studies suggesting cut-offs for adrenalectomy patients. Methods Urinary metanephrine and normetanephrine concentrations in adrenalectomy patients and two controls were compared and hormonal concentrations were evaluated via time intervals after surgery. Results The median urinary metanephrine level after unilateral adrenalectomy was lower than that of the non-pheochromocytoma controls but comparable to healthy controls. Urinary normetanephrine concentrations did n

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Pamporaki, Christina, Michael Bursztyn, Manja Reimann, et al. "Seasonal variation in plasma free normetanephrine concentrations: implications for biochemical diagnosis of pheochromocytoma." European Journal of Endocrinology 170, no. 3 (2014): 349–57. http://dx.doi.org/10.1530/eje-13-0673.

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BackgroundHigher plasma concentrations of catecholamines in winter than in summer are established; whether this impacts plasma concentrations of metanephrines used for the diagnosis of pheochromocytoma is unknown.ObjectiveIn this study, we examined seasonal variations in plasma concentrations of metanephrines, the impact of this on diagnostic test performance and the influences of forearm warming (‘arterialization’ of venous blood) on blood flow and measured concentrations.MethodsMeasurements of plasma concentrations of metanephrines were recorded from 4052 patients tested for pheochromocytoma

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Bloomer, Zachary W., Elizabeth M. Bauer, Thanh D. Hoang, and Mohamed K. M. Shakir. "ELETRIPTAN (RELPAXA™) CAUSING FALSE POSITIVE ELEVATIONS IN URINARY METANEPHRINES." AACE Clinical Case Reports 6, no. 6 (2020): e286-e289. http://dx.doi.org/10.4158/accr-2020-0225.

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Objective: Pheochromocytoma is diagnosed biochemically by demonstrating an excessive production of catecholamines and their metabolites in the blood and urine. However, these tests are at times fraught with false-positive results due to drug effects. We report here a patient with markedly elevated urinary metanephrines associated with the use of eletriptan for migraine treatment. Methods: A literature search was conducted using the PubMed and Google Scholar databases for eletriptan and false positive metanephrine elevation. Urine and plasma metanephrine tests were performed via liquid chromato

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Crockett, David K., Elizabeth L. Frank, and William L. Roberts. "Rapid Analysis of Metanephrine and Normetanephrine in Urine by Gas Chromatography-Mass Spectrometry." Clinical Chemistry 48, no. 2 (2002): 332–37. http://dx.doi.org/10.1093/clinchem/48.2.332.

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Abstract Background: Widely used HPLC methods for quantification of metanephrine and normetanephrine in urine often have long analysis times and are frequently plagued by drug interferences. We describe a gas chromatography-mass spectrometry method designed to overcome these limitations. Methods: Metanephrine and normetanephrine conjugates were converted to unconjugated metanephrine and normetanephrine by acid hydrolysis. To avoid the rapid decomposition of the deuterated internal standards (metanephrine-d3 and normetanephrine-d3) under hydrolysis conditions, the internal standards were added

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Peitzsch, Mirko, Talia Novos, Denise Kaden, et al. "Harmonization of LC-MS/MS Measurements of Plasma Free Normetanephrine, Metanephrine, and 3-Methoxytyramine." Clinical Chemistry 67, no. 8 (2021): 1098–112. http://dx.doi.org/10.1093/clinchem/hvab060.

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Abstract Background Plasma-free normetanephrine and metanephrine (metanephrines) are the recommended biomarkers for testing of pheochromocytoma and paraganglioma (PPGL). This study evaluated the status of harmonization of liquid chromatography-tandem mass spectrometry-based measurements of plasma metanephrines and methoxytyramine and clinical interpretation of test results. Methods 125 plasma samples from patients tested for PPGLs were analyzed in 12 laboratories. Analytical performance was also assessed from results of a proficiency-testing program. Agreement of test results from different la

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Troshina, E. A., D. G. Bel'tsevich, and M. Iu Iukina. "Laboratory diagnostics of pheochromocytoma." Problems of Endocrinology 56, no. 4 (2010): 39–43. http://dx.doi.org/10.14341/probl201056439-43.

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Biochemical diagnosis of pheochromocytoma is based on the measurement of altered levels of normetanephrine and metanephrine in plasma or 24-hour urine samples. Plasma normetanephrine and metanephrine levels four times the upper limit of the normal value or metanephrine and normetanephrine excretion in urine above 700 and 1500 mcg/24 hours respectively makes further testing unnecessary and subsequent examination must be focused on the determination of tumour localization. In patients presenting with the above parameters elevated within the "grey zone", effect of medicinal products needs to be e

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Canfell, P. C., S. R. Binder, and H. Khayam-Bashi. "Pediatric reference intervals for normetanephrine/metanephrine." Clinical Chemistry 32, no. 1 (1986): 222–23. http://dx.doi.org/10.1093/clinchem/32.1.222.

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Roy, Alec, David Pickar, Patrice Douillet, Farouk Karoum, and Markku Linnoila. "Urinary monoamines and monoamine metabolites in subtypes of unipolar depressive disorder and normal controls." Psychological Medicine 16, no. 3 (1986): 541–46. http://dx.doi.org/10.1017/s0033291700010308.

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SynopsisAn examination was made of urinary catecholamine and metabolite outputs in 28 unipolar depressed patients and 25 normal controls. The total group of depressed patients had significantly higher urinary outputs of norepinephrine (NE) and its metabolite normetanephrine (NM), and significantly lower urinary outputs of the dopamine metabolite dihydroxyphenylacetic acid (DOPAC), than controls. Patients who met DSM-III criteria for a major depressive episode with melancholia (N = 8) had significantly higher urinary outputs of normetanephrine than controls, whereas patients with a major depres

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Eisenhofer, Graeme, Jacques WM Lenders, David S. Goldstein, et al. "Pheochromocytoma Catecholamine Phenotypes and Prediction of Tumor Size and Location by Use of Plasma Free Metanephrines." Clinical Chemistry 51, no. 4 (2005): 735–44. http://dx.doi.org/10.1373/clinchem.2004.045484.

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Abstract Background: Measurements of plasma free metanephrines (normetanephrine and metanephrine) provide a useful test for diagnosis of pheochromocytoma and may provide other information about the nature of these tumors. Methods: We examined relationships of tumor size, location, and catecholamine content with plasma and urinary metanephrines or catecholamines in 275 patients with pheochromocytoma. We then prospectively examined whether measurements of plasma free metanephrines could predict tumor size and location in an additional 16 patients. Results: Relative proportions of epinephrine and

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Dissertations / Theses on the topic "Normetanephrine"

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Cameron, Kristin Nicole. "The effects of illness on urinary catecholamines and their metabolites in dogs." Thesis, Virginia Tech, 2010. http://hdl.handle.net/10919/76977.

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Background: Urinary catecholamines and metanephrines have been proposed as a diagnostic tool for identifying canine pheochromocytomas, but the effects of critical illness on urine concentrations of catecholamines and metanephrines is currently unknown. Objectives: To examine the effects of illness on urine concentrations of catecholamines and metanephrines in dogs. Animals: Twenty-five critically ill dogs and twenty-five healthy age- and gender-matched control dogs. Methods: Prospective observational study. Urine was collected from healthy and critically ill dogs and urine concentrat

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Eisenhofer, Graeme, Sebastian Brown, Mirko Peitzsch, et al. "Levodopa therapy in Parkinson’s disease: Influence on liquid chromatographic tandem mass spectrometricbased measurements of plasma and urinary normetanephrine, metanephrine and methoxytyramine." Sage, 2014. https://tud.qucosa.de/id/qucosa%3A35427.

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Background: Medication-related interferences with measurements of catecholamines and their metabolites represent important causes of false-positive results during diagnosis of phaeochromocytomas and paragangliomas (PPGLs). Such interferences are less troublesome with measurements by liquid chromatography with tandem mass-spectrometry (LC-MS/MS) than by other methods, but can still present problems for some drugs. Levodopa, the precursor for dopamine used in the treatment of Parkinson’s disease, represents one potentially interfering medication. Methods: Plasma and urine samples, obtained from

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Adaway, Joanne E., Mirko Peitzsch, and Brian G. Keevil. "A novel method for the measurement of plasma metanephrines using online solid phase extraction-liquid chromatography tandem mass spectrometry." Sage, 2015. https://tud.qucosa.de/id/qucosa%3A35429.

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Background: Measurement of plasma metanephrine, normetanephrine and 3-methoxytyramine is useful in the diagnosis of phaeochromocytomas, but many assays require a large volume of plasma due to poor assay sensitivity, and often require lengthy sample preparation. Our aim was to develop a method for measurement of plasma metanephrines using a small sample volume with minimal hands-on preparation. Methods: Samples were deproteinised using 10 K spin filters prior to online solid phase extraction using a Waters Acquity UPLC Online SPE Manager (Waters, Manchester, UK) coupled to a Waters Xevo TQ-S ma

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Peterson, Zlatuse Durda. "Analysis of Clinically Important Compounds Using Electrophoretic Separation Techniques Coupled to Time-of-Flight Mass Spectrometry." BYU ScholarsArchive, 2004. https://scholarsarchive.byu.edu/etd/23.

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Capillary electrophoretic (CE) separations were successfully coupled to time-of-flight mass spectrometric (TOFMS) detection for the analysis of three families of biological compounds that act as mediators and/or indicators of disease, namely, catecholamines (dopamine, epinephrine, norepinephrine) and their O-methoxylated metabolites (3-methoxytyramine, norepinephrine, and normetanephrine), indolamines (serotonin, tryptophan, and 5-hydroxytryptophan), and angiotensin peptides. While electrophoretic separation techniques provided high separation efficiency, mass spectrometric detection afforded

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Book chapters on the topic "Normetanephrine"

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Aydogan, Berna Imge, Pinar Kubilay, Ali Riza Uysal, and Sevim Güllü. "Sulfasalazine related false positive urinary normetanephrine." In The Endocrine Society's 95th Annual Meeting and Expo, June 15–18, 2013 - San Francisco. The Endocrine Society, 2013. http://dx.doi.org/10.1210/endo-meetings.2013.ahpaa.11.mon-50.

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Gabler, Jessica, and Sihe Wang. "Quantification of Metanephrine and Normetanephrine in Urine Using Liquid Chromatography-Tandem Mass Spectrometry." In Clinical Applications of Mass Spectrometry in Biomolecular Analysis. Springer New York, 2016. http://dx.doi.org/10.1007/978-1-4939-3182-8_17.

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Lenders, Jacques W. M., and Graeme Eisenhofer. "Normetanephrine and Metanephrine." In Encyclopedia of Endocrine Diseases. Elsevier, 2017. http://dx.doi.org/10.1016/b978-0-12-801238-3.03975-1.

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Lenders, Jacques W. M., and Graeme Eisenhofer. "Normetanephrine and Metanephrine." In Encyclopedia of Endocrine Diseases. Elsevier, 2004. http://dx.doi.org/10.1016/b0-12-475570-4/00929-x.

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Raum, William J. "[65] Enzymatic radioimmunoassay of epinephrine, norepinephrine, metanephrine, and normetanephrine." In Methods in Enzymology. Elsevier, 1987. http://dx.doi.org/10.1016/s0076-6879(87)42067-3.

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"Normetanephrin." In Springer Reference Medizin. Springer Berlin Heidelberg, 2019. http://dx.doi.org/10.1007/978-3-662-48986-4_312761.

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