To see the other types of publications on this topic, follow the link: Normocytic normochromic.

Journal articles on the topic 'Normocytic normochromic'

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the top 50 journal articles for your research on the topic 'Normocytic normochromic.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Browse journal articles on a wide variety of disciplines and organise your bibliography correctly.

1

Yu, Zhou, Leann Michelle Blankenship, Mohammed Ibrahim, et al. "Does Normal Reticulocyte Hemoglobin Rule out Iron Deficiency As a Cause of Normocytic Normochromic Anemia?" Blood 128, no. 22 (2016): 4826. http://dx.doi.org/10.1182/blood.v128.22.4826.4826.

Full text
Abstract:
Abstract Background: Normochromic, normocytic anemia is the most frequently encountered type of anemia with a wide differential diagnosis. Iron studies are frequently ordered as part of the anemia work up as iron deficiency anemia could be potentially normocytic and normochromic. Recently reticulocyte hemoglobin has emerged as a marker to help identify early stages of iron deficiency at a time that other traditional biochemical studies for iron deficiency are non-informative. We hypothesize that normal reticulocyte hemoglobin level is a sensitive negative predictor of iron deficiency. Aim:To evaluate whether a normal reticulocyte hemoglobin level can be used to exclude iron deficiency anemia in patients with normocytic normochromic anemia. Methods:We reviewed the results of all hematological tests obtained as a part of hematopathology consults which were requested between January to April of 2016. Electronic medical records were screened for inclusion criteria. We included patient with hemoglobin less than 12g/dl, normal MCV (80-100) and normal reticulocyte hemoglobin level (>31 pg). We calculated the percentage of patients who had normal iron store suggested by ferritin, total iron binding capacity and iron saturation studies. Results:We included 41 patients who has normocytic normochromic anemia with normal reticulocyte hemoglobin level. 39 out of 41 patients have normal iron studies indicating iron deficiency anemia was not the cause of anemia. The overall negative predictive value is 95.1%. Among the two patients whose ferritin levels are mildly decreased, suggesting possible iron deficiency, one patient had a blood transfusion prior to checking reticulocyte hemoglobin level. The other patient donates blood frequently and was started on oral iron supplementation trial without any hemoglobin improvement after two weeks. It appeared that these two patients might not have true iron deficiency. Conclusion: Measurement reticulocyte hemoglobin level can serve as a useful marker to rule out iron deficiency as a cause of normocytic normochromic anemia. Serum Iron and ferritin studies are not indicated in patients with normocytic normochromic anemia with normal reticulocyte hemoglobin. Disclosures No relevant conflicts of interest to declare.
APA, Harvard, Vancouver, ISO, and other styles
2

Elis, Avishay, Mordchai Ravid, Yosef Manor, Tamir Bental, and Michael Lishner. "A Clinical Approach to “Idiopathic” Normocytic-Normochromic Anemia." Journal of the American Geriatrics Society 44, no. 7 (1996): 832–34. http://dx.doi.org/10.1111/j.1532-5415.1996.tb03743.x.

Full text
APA, Harvard, Vancouver, ISO, and other styles
3

Bebeshko, V. G., K. M. Bruslova, N. M. Tsvietkova, L. O. Gonchar, and O. G. Aleksieiev. "Causal-Investigative Analysis of the Formation of Anemia in Children." Ukraïnsʹkij žurnal medicini, bìologìï ta sportu 5, no. 5 (2020): 271–77. http://dx.doi.org/10.26693/jmbs05.05.271.

Full text
Abstract:
The purpose of the study was to determine the main causal factors in the formation of anemia in children of Ukraine, depending on the morphometric changes in erythrocytes of blood, indicators of iron metabolism for the formation of a risk group for oncohematological diseases. Material and methods. 770 children were examined: 724 with anemia, 46 with acute lymphoblastic leukemia. We studied the parameters of the erythrocyte lineage of hematopoiesis, morphometric parameters of erythrocytes, indicators of iron metabolism (serum iron, ferritin, transferrin, the transferrin saturation with iron, hematocrit, the content of δ-aminolevulinic acid and coproporphyrin in urine, pituitary thyroid stimulating hormone depending on the type of somatic pathology. Anemic states were distributed taking into account the average erythrocyte volume and the average hemoglobin content in the erythrocyte, and dividing diagnoses microcytic-hypochromic or normocytic-normochromic anemia, respectively. Results and discussion. The study showed that in children with normocytic-normochromic anemia, the number of erythrocytes and hematocrit were lower than in patients with microcytic-hypochromic anemia, while average erythrocyte volume, average hemoglobin content, serum iron, serum ferritin and transferrin saturation with iron were higher. The number of reticulocytes in the peripheral blood in all the examined subjects was standard. That is, the anemic conditions in children differed in ferrokinetic parameters, in particular, with and without iron deficiency. Taking into account the age of the children and the reasons for the development of anemia, a third of the girls of puberty with microcytic-hypochromic anemia had menorrhagias. In children under 6 years of age with normocytic-normochromic anemia, diseases of the gastrointestinal tract were more often registered; in the older 6 years – gastrointestinal diseases, helminthiasis and allergic reactions compared with patients with microcytic-hypochromic anemia. The development of normocytic-normochromic anemia in children and the functioning of the gastrointestinal tract were influenced by drug treatment for chronic pathology in the body. All children with anemia had an irrational diet. Porphyria was diagnosed in 3.8% of children with microcytic-hypochromic anemia. In 12.7% of children with normocytic-normochromic anemia, the serum thyroid stimulating hormone level was at the upper limit of the reference value (mean 3.3±0.6) mU/L), which correlated with a reduced number of erythrocytes in blood (r = -0.65) and increased values of average erythrocyte volume (r = 0.41) and average hemoglobin content (r = 0.35), and indicates changes in the erythrocyte lineage of hematopoiesis associated with the initial manifestations of thyroid hypofunction. An excess of iron was observed in 7.1% of older boys with normocytic-normochromic anemia, which requires additional examination. In patients with acute lymphoblastic leukemia were diagnosed with normocytic-normochromic anemia of varying severity. The serum ferritin level was (272.1±28.4) ng/ml and was significantly higher than in children with normocytic-normochromic anemia. In 12 of 46 patients, transferrin saturation with iron was increased and amounted to (70.2±2.3)%. Moreover, the higher the level of serum iron and serum ferritin, the higher was the transferrin saturation with iron (rs = 0.5; rs = 0.85). An inverse correlation was established between transferrin saturation with iron, patient survival (rs = -0.45) and a higher probability of death (rs = -0.46). Conclusion. Children with normocytic-normochromic anemia require in-depth examination and constitute a risk group for the development of myelodysplastic syndrome and leukemia
APA, Harvard, Vancouver, ISO, and other styles
4

Gul, Ambreen, Umarah Nisar, Safia Rahman, Zahoor Ullah, Muhammad Furqan, and Momina Haq. "PATTERN OF ANEMIA IN DIABETIC PATIENTS PRESENTING TO PRIVATE SECTOR`S TERTIARY CARE HOSPITALS IN PESHAWAR." Journal of Medical Sciences 30, no. 04 (2022): 246–49. http://dx.doi.org/10.52764/jms.22.30.4.2.

Full text
Abstract:
Objective: To determine the frequency and type of anemia based on MCV in diabetic patients. Materials and Methods: A Retrospective descriptive study, done at Peshawar Medical College, Peshawar, and its affiliated teaching hospitals from January 2016 to August 2018. It was a Laboratory and Medical OPD record-based study of 450 diabetic patients presenting to these teaching hospitals. Results: Among 450 diabetic patients, 283(63%) were having anemia (Hb less than 13.5 g/dl in males and 11.5 g/dl in females). Among those who had anemia, 102(36%) had microcytic hypochromic, 176(62%) had normochromic normocytic and 6(2%) had macrocytic anemia on the basis of the mean corpuscular volume of more than 80, 80-95 and 95 fl respectively. Conclusion: More than 60 % of diabetic patients presented with anemia predominantly suffering from normocytic and normochromic anemia. KEYWORDS: Anemia, Diabetes, hemoglobin, MCV, Normocytic and Normochromic anemia.
APA, Harvard, Vancouver, ISO, and other styles
5

T., Glebova,. "Anemic Syndrome in Children in the Children’s Regional Hospital." Bulletin of Science and Practice, no. 1 (January 15, 2023): 197–99. http://dx.doi.org/10.33619/2414-2948/86/26.

Full text
Abstract:
The study of a general blood test determining the nature of anemic syndrome in young children (0-12 years old) and children (3-6 years old) with infectious processes in the infectious department of the Penza Regional Children's Hospital was carried out. In the study, 4 groups were identified according to blood parameters in the age group 0-12 years. The study of the indicators of the general blood test showed that the first group cannot be attributed to the manifestations of severe anemia syndrome. In the second – normochromic, normocytic anemia syndrome. The third group had a manifestation of anemic normochromic, normocytic syndrome. In children in the fourth group, microcytosis of erythrocytes, anisocytosis, poikilocytosis and hypochromia were detected in blood smears. The data of the general blood test indicated the presence of concomitant anemia microcytic, hypochromic syndrome in children. And in children in the age group of 3-6 years, only in 25.8% of cases, the manifestation of anemic syndrome was found in the test’s of 1010 children. In children, the revealed anemic syndrome corresponded to the normochromic, normocytic process. Based on the data obtained, it can be concluded that young children (0-12 years old) and aged 3-6 years who are being treated for the underlying disease have concomitant anemia syndromes in most cases of normochromic, normocytic and in a minority of cases of hypochromic, microcytic nature.
APA, Harvard, Vancouver, ISO, and other styles
6

Rada, N., R. El Qadiry, F. Bennaoui, G. Draiss, and M. Bouskraoui. "Sickle Cell Disease Revealed by Soft Tissue Abscess: One Case Report." Open Infectious Diseases Journal 10, no. 1 (2018): 139–41. http://dx.doi.org/10.2174/1874279301810010139.

Full text
Abstract:
Introduction: Sickle cell disease is a haemoglobinopathy characterized by the occurrence of vaso-occlusive crises and osteoarticular complications. Case-Report: We report the case of an infant with sickle cell disease revealed by a bilateral abscess of the feet. Our patient is an 18-month-old infant who has had bilateral swelling of the feet for a week with fever of 40 °C, a CRP of 129 mg/l and a leukocytosis of 32,000 elements/mm3 together with normochromic normocytic anemia at 7.9 g/dl. The diagnosis of abscess was taken and a puncture was made finding a purulent fluid with isolation of Salmonella. In front of the bilateral character, Salmonella isolation and normochromic normocytic anemia, electrophoresis of hemoglobin was requested confirming the diagnosis of sickle cell disease. The progress was positive with hydration and antibiotic therapy. Conclusion: Soft-tissue Salmonella infections must lead to thinking of sickle cell disease as a diagnosis especially with normochromic normocytic anemia combined.
APA, Harvard, Vancouver, ISO, and other styles
7

Indrati, Agnes Rengga, Yehezkiel Yonathan, Hendro Hendro, Lazuardi Dwipa, and Cissy Kartasasmita. "Characteristics of Anemia in the Elderly: Hospital-Based Study in West Java." INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY 29, no. 3 (2023): 220–23. http://dx.doi.org/10.24293/ijcpml.v29i3.2018.

Full text
Abstract:
Geriatric anemia can cause many problems and is a major health condition worldwide and in Indonesia. It is important to know the characteristics and prevalence of anemia among geriatrics in Indonesia, especially in West Java. By using simple hematology parameters to detect anemia in geriatrics, and then giving adequate treatment, morbidity, and mortality due to anemia may decrease in geriatrics. This study aimed to identify the type of anemia, etiology, age, gender, and prevalence of elderly patients with anemia in West Java. This was a cross-sectional study. Patients above 59 years old attending the geriatric clinic in Hasan Sadikin General Hospital and the geriatric community was included in this study to be evaluated for anemia, the characteristics of anemia (normocytic, microcytic, and macrocytic) based on MCV and MCHC, age group (<=65 and > 65 year old), and gender. Among 247 elderly patients, anemia was found in 33 patients (13.64%) and mostly found in females. Mostly represented as normochromic normocytic anemia (78.8%) and microcytic hypochromic anemia (21.2%), respectively. Individuals older than 65 years old were mostly presented with microcytic hypochromic anemia (66.7%). Meanwhile, normocytic normochromic anemia was more commonly found in individuals below 65 years old (12.1%). Anemia was commonly found in people older than 65 years old. The most common type of anemia in geriatrics in West Java was normocytic normochromic. Females experience anemia more than males.
APA, Harvard, Vancouver, ISO, and other styles
8

Asano, Takeshi, Mariko Sudoh, Makoto Watanabe, and Osamu Fujino. "Concomitant Severe Normocytic and Normochromic Anemia in Poststreptococcal Acute Glomerulonephritis." Journal of Nippon Medical School 76, no. 5 (2009): 272–74. http://dx.doi.org/10.1272/jnms.76.272.

Full text
APA, Harvard, Vancouver, ISO, and other styles
9

Yadav, Rakesh K., Mansoor Ahmad, Manoj K. Mathur, and Vishal Dhingra. "Study of prevalence and types of anemia in primary hypothyroidism." International Journal of Advances in Medicine 6, no. 5 (2019): 1574. http://dx.doi.org/10.18203/2349-3933.ijam20194221.

Full text
Abstract:
Background: Hypothyroidism is common disease with varying frequency between countries. Anemia in hypothyroidism can be normocytic normochromic, microcytic hypochromic and macrocytic hypochromic. Anemia severity is associated with hypothyroidism degree. Objective of this study to study the association between anemia and hypothyroidism and prevalence and types of anemia in primary hypothyroidism (subclinical and overt both).Methods: This cross sectional study was carried out at tertiary care hospital in North India. Newly diagnosed 100 primary hypothyroid patients and 100 controls with age and sex matched evaluated for anemia. Prevalence and types of anemia were studied and severity of anemia was correlated with that of hypothyroidism.Results: Anemia was observed in 90 patients with hypothyroidism. Symptoms due to anemia were higher in cases than in controls. RBCs morphology showed normocytic normochromic in 59, microcytic hypochromic in 26 and macrocytic hypochromic in 15 cases. Serum anti-TPO positivity was present in 71.1% in cases as compared to 33.33% in controls. Anemia was severe in cases with high TSH.Conclusions: Anemia was more prevalent in cases of hypothyroidism than in euthyroid controls. Normocytic normochromic type of anemia was most common type in this study. Serum anti-TPO positivity was 71.1% in cases. There was statistically significant negative correlation between TSH and haemoglobin. Symptoms of anemia were more in hypothyroid patients than in euthyroid anemic patients.
APA, Harvard, Vancouver, ISO, and other styles
10

Kim, Young Ju, Hyeona Bae, Sun Woo Shin, et al. "Two Clinical Cases of Feline Hemoplasmosis in Korea." Korean Journal of Parasitology 60, no. 2 (2022): 127–31. http://dx.doi.org/10.3347/kjp.2022.60.2.127.

Full text
Abstract:
Feline hemotropic mycoplasmosis (hemoplasmosis) is an infection of the red blood cells caused by the Mycoplasma haemofelis (Mhf), Candidatus Mycoplasma haemominutum (CMhm), and Candidatus Mycoplasma turicensis (CMt). The existence of Mhf, CMhm, and CMt has been demonstrated in feral cats in Korea using molecular methods, but no clinical cases have yet been reported. This study reports 2 clinical cases of hemotropic mycoplasmosis caused by CMhm and CMt in 2 anemic cats. The first case was a client-owned intact female domestic shorthair cat that presented with fever, pale mucous membranes, and normocytic normochromic non-regenerative anemia. Prior to referral, an immunosuppressive prednisolone dose was administered at the local veterinary clinic for 1 month. The cat was diagnosed with high-grade alimentary lymphoma. Organisms were found on the surface of the red blood cells on blood smear examination. The second case was of a rescued cat that presented with dehydration and fever. The cat had normocytic normochromic non-regenerative anemia. Necropsy revealed concurrent feline infectious peritonitis. Polymerase chain reaction assay targeting 16S rRNA revealed CMhm infection in case 1 and dual infection of CMhm and CMt in case 2. Normocytic normochromic non-regenerative anemia was observed in both cats before and during the management of the systemic inflammation. This is the first clinical case report in Korea to demonstrate CMhm and CMt infections in symptomatic cats.
APA, Harvard, Vancouver, ISO, and other styles
11

Gray, Naomi D., Duran J. Sood, and Bechtold H. Tamela. "Comorbid normochromic and normocytic anemia in coronary artery disease: retrospective study." American Journal of BioMedicine 11, no. 2 (2023): 96–109. http://dx.doi.org/10.18081/2333-5106/2023.11/96.

Full text
Abstract:
The study's objective was to ascertain the prevalence and defining characteristics of anemia in coronary artery disease patients. Retrospectively, 534 patients with comorbid anemia and coronary artery disease were examined. All patients were determined to have ongoing coronary supply route infection. The normal time of examined patients was 76.2 ± 5.11. Males with hemoglobin levels below 13.5 mg/dL and females with hemoglobin levels below 11.5 mg/dL were diagnosed with comorbid anemia. The patients were randomized by sex, age, and type of coronary corridor infection. Among all analyzed patients with coronary vein sickness frailty is viewed as in almost 75% of cases, which matches with the writing information. In individuals after 50 pallor is more normal in men than in ladies, while in youthful and moderately aged patients weak condition is more run of the mill in females. Just in under 90 case reports the determination of frailty was kept in the last clinical analysis during patients' release from the emergency clinic, in one more case low hemoglobin level was not thought about by doctors. Roughly only 35% of all instances of serious paleness were not analyzed in a medical clinic and no fitting rectification of hemoglobin level was performed. The rate of sickliness doesn't rely upon the type of constant coronary vein infection. In many patients with coronary course sickness comorbid sickliness is of normochromic and normocytic character. Alongside movement of the seriousness of the comorbid paleness, a genuinely critical increment of the hospitalization time frame is noticed. In patients with coronary corridor sickness and comorbid pallor, the recurrence of hospitalizations each year is additionally expanded alongside iron deficiency level of seriousness. In conclusion, constant types of coronary corridor sickness in old and feeble patients in 69.89% of cases are confounded by comorbid paleness of various levels of seriousness. In more established patients with coronary course sickness, the weak disorder is most frequently brought about by respiratory illnesses, stomach ulcers, and duodenal ulcers, diseases of various limitations. In many patients with coronary conduit sickness comorbid sickliness is of normochromic and normocytic character.
APA, Harvard, Vancouver, ISO, and other styles
12

Henrika, Fify, T. Silangit, and Riadi Wirawan. "ANEMIA DAN DEFISIENSI BESI PADA SISWA SLTP NEGERI I CURUG, TANGERANG." INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY 15, no. 1 (2018): 5. http://dx.doi.org/10.24293/ijcpml.v15i1.943.

Full text
Abstract:
A research was conducted to 69 female students from a junior high school (SLtP) Negeri I Curug, tangerang aged 12–14 yearsto obtain percentages of anemia and iron deficiency in female adolescents. Anemia was found on 10.2% of the students, with 4.3%of normocytic normochromic anemia and 5.8% of microcytic hypochromic anemia. Microcytic hypochromic erythrocytes was foundon 21.7% of the subjects which consist of 2.9% iron deficiency anemia, 1.4% phase 2 iron deficiency (latent) with possibility ofhemoglobinopathy, and 2.9% phase 1 iron deficiency (pre-latent) with possibility of hemoglobinopathy. Anemia without iron deficiencywith possibility of chronic diseases and/or hemoglobinopathy was 2.9%, and without anemia nor iron deficiency but with possibility ofhemoglobinopathy was 11.6%. Iron deficiency was found among 26.1% of subjects which consist of 11.6% pre-latent iron deficiency,8.7% latent iron deficiency, and 5.8% iron deficiency anemia with 2.9% and 2.9% were normocytic normochromic anemia andmicrocytic hypochromic anemia, respectively.
APA, Harvard, Vancouver, ISO, and other styles
13

Jitendra, Falodia. "A Study to Assess the Changes in the Hematological Manifestation in Chronic Kidney Disease Patients." International Journal of Pharmaceutical and Clinical Research 15, no. 7 (2023): 988–91. https://doi.org/10.5281/zenodo.11672380.

Full text
Abstract:
Chronic kidney disease (CKD) is a global public health problem, with greater burden and very high cost of care especially in developing countries like India. The objective of this study is to assess the hematological profile of our subjects with CKD. Patients admitted as inpatients in the Department of medicine at Sardar Patel Medical College Hospital, during the period of 2018-2021 were included in this study.13.00% patients had microcytic hypochromic anemia, 91.00% patients had normocytic normochromic, 25.00% patients had relative neutrophila, 11.00% patients had leucocytosisand  9.00% patients had thrombocytopenia. Anemia is a very common clinical manifestation in patients of Chronic Kidney Disease. The most common morphological type of Anemia seen in our study was Normocytic normochromic type. Management of anemia with Iron and Erythropoeitin therapy is an important therapeutic intervention in the optimum treatment of patients with Chronic Kidney Disease.    
APA, Harvard, Vancouver, ISO, and other styles
14

KACZMAREK, BEATA, ŁUKASZ ADASZEK, and KLAUDIA MIĘTKIEWSKA. "Effect of mineral deficiencies on the red blood cell parameters in cattle." Medycyna Weterynaryjna 77, no. 09 (2021): 6570–2021. http://dx.doi.org/10.21521/mw.6570.

Full text
Abstract:
Mineral deficiencies are a common problem in dairy herds around the world. Currently, they most often occur in a subclinical form or with atypical symptoms, which makes their diagnosis difficult. New methods and possibilities of identifying mineral deficiencies are being sought. Hematological changes may occur in the early stages of the development of deficiency diseases, and their detection may be helpful in the early diagnosis of diseases. The aim of the article is to present the most important information on disorders in the red blood cell system in the course of mineral deficiencies in dairy cattle. Hematological tests should become one of the most important elements facilitating the determination of the health condition of cows and enabling the correct diagnosis and therapy of cattle diseases. Copper, iron, magnesium and phosphorus deficiencies cause changes in hematological parameters. In iron and copper deficiency, there are microcytic, hypochromatic or normocytic, normochromic anemia. On the other hand, in the deficiency of magnesium and phosphorus, there is normocytic, normochromic anemia.
APA, Harvard, Vancouver, ISO, and other styles
15

Trivedi, Dhara P., Hetal A. Joshi, and Vijay C. Popat. "Three rare and accidental findings of hemoglobinopathies encountered in high-performance liquid chromatography: case series." International Journal of Research in Medical Sciences 11, no. 1 (2022): 328. http://dx.doi.org/10.18203/2320-6012.ijrms20223656.

Full text
Abstract:
Hemoglobinopathies are the leading cause of some major genetic and social health problem in India. Among all hemoglobinopathies, sickle cell disorder and thalassemia are commonly found in Gujarat state. Double heterozygous state of hemoglobin S and D, hemoglobin E trait, hemoglobin D disease are very uncommon. In present instance, one case of 25-year-old male was diagnosed with sickle cell hemoglobin D disease. The case was confirmed through slide-based sickle test and high-performance liquid chromatography (HPLC). The peripheral smear findings showed presence of microcytic hypochromic red blood cells (RBCs) and many sickled RBCs. Ultrasonography (USG) findings showed hepatomegaly. Second case of 30-year-old female was diagnosed with hemoglobin E trait. The case was confirmed by HPLC. The peripheral findings showed normocytic normochromic RBCs and occasional target cells. Presence of gross hepatomegaly on palpation. Third case of 20-year-old female was diagnosed with hemoglobin D trait. The case was confirmed by HPLC. The peripheral findings showed normocytic normochromic RBCs.
APA, Harvard, Vancouver, ISO, and other styles
16

Asghar, Rabiah, Javera Tariq, Nabeela Naeem, Anila Zafar, Khadija Qureshi, and Shameela Majeed. "Comparison of peripheral blood smear examination with automated haematology analyzer for diagnosing different types of anemia." Professional Medical Journal 28, no. 10 (2021): 1433–37. http://dx.doi.org/10.29309/tpmj/2021.28.10.6179.

Full text
Abstract:
Objective: This study aims to determine diagnostic accuracy of peripheral blood smear and automated haematology analyzer and to determine frequency of different types of anemia diagnosed by peripheral blood smear and automated hematology analyzer. Study Design: Cross Sectional study. Setting: Department of Pathology, Rawal Institute of Health Sciences, Islamabad. Period: November 2015 to April 2016. Material & Methods: Sample size of 149 suspected anemia patients was calculated using WHO calculator with 95% confidence interval. Research approval was taken from hospital ethical board. Patients were approached through non probability consecutive sampling method. Both peripheral blood smear examination and automated haematology analysis of each sample was performed. Diagnostic accuracy and frequency of anemia types was measured. Data analysis was done with the help of SPSS version 25. Chi-square and fissure exact test and ROC curve analysis was applied and significant (p<0.05) results were reported. Results: Total 149 patients were included in study. There were 42(28.2%) male and 107(71.8%) female. Mean age of patients was 35.1±2.1SD. Peripheral blood smear and automated haematology analyzer showed sensitivity (68% vs 92%), specificity (59% vs 88%), PPV (72% vs 92%), NPV (55% vs 88%) and diagnostic accuracy (64% vs 91) respectively. Most common type of anemia diagnosed with peripheral blood smear was microcytic hypochromic anemia with raised RDW 36.7% followed by normocytic normochromic anemia with raised RDW 13.3% and macrocytic anemia (p=0.001) while in automated haematology analyzer microc ytic hypochromic anemia with raised RDW54.4% followed by normochromic normocytic anemoia with normal RDW 11.1% (p=0.000). Conclusion: Automated haematyology analyzer had high diagnostic accuracy for diagnosis of anemia. Microcytic hypochromic anemia and normocytic normochromic are most common anemias diagnosed by peripheral blood smear and automated hematology analyzer and peripheral blood smear cannot be completely replaced by automated haemolytic analyzer. However, if both methods are used simultaneously, more accurate results can be obtained.
APA, Harvard, Vancouver, ISO, and other styles
17

Tănăsescu, Maria-Daniela, Ștefan Popescu, Alexandru Mincă, et al. "Paragangliomas and Anemia: Literature Review and Case Report." Medicina 59, no. 11 (2023): 1925. http://dx.doi.org/10.3390/medicina59111925.

Full text
Abstract:
Paragangliomas are rare neuroendocrine tumors that arise from the extra-adrenal autonomic paraganglia, i.e., small organs consisting mainly of neuroendocrine cells that are derived from the embryonic neural crest and have the ability to secrete catecholamines. Paragangliomas can derive from either parasympathetic or sympathetic paraganglia. Most of the parasympathetic ganglia-derived paragangliomas are nonfunctional, and symptoms result from mass effect. Conversely, the sympathetic paragangliomas are functional and produce catecholamine. Although such patients could have symptoms similar to pheochromocytoma, mass effect symptoms, or non-specific symptoms, being benign tumors, they can also present with anemia, specifically iron-deficiency anemia. Considering that neoplastic pathology is chronically accompanied by moderate, normochromic, normocytic anemia, association between paragangliomas that are mostly benign but with a potential degree of malignancy and anemia is not as frequent as expected, with only 12 cases reported in the literature. We report a case of a 54-year-old female patient diagnosed with a paraganglioma of the carotid glomus accompanied by severe normochromic, normocytic anemia, which reached normal limits after excision of the paraganglioma.
APA, Harvard, Vancouver, ISO, and other styles
18

O’Brien, A. A. J., D. P. Moore, and J. A. B. Keogh. "The response of the normochromic normocytic anaemia of chronic renal failure to Desferrioxamine." Irish Journal of Medical Science 156, no. 8 (1987): 236–37. http://dx.doi.org/10.1007/bf02954052.

Full text
APA, Harvard, Vancouver, ISO, and other styles
19

Manoj U Mahajan, Sunil Goel, Harsh Patel, et al. "Idiopathic pure red cell aplasia: A case series from India." Asian Journal of Medical Sciences 14, no. 5 (2023): 253–56. https://doi.org/10.71152/ajms.v14i5.3734.

Full text
Abstract:
Pure red cell aplasia (PRCA) is a rare hematologic disorder characterized by normocytic normochromic anemia with reticulocytopenia and depleted erythroid precursors. It is reported mainly from western countries. We report our experience in two patients of PRCA from India, the clinical characteristics, differential diagnosis, and their management. Our patients showed improvements following treatment with corticosteroids, blood transfusion, and/or rituximab.
APA, Harvard, Vancouver, ISO, and other styles
20

Mahajan, Manoj U., Sunil Goel, Harsh Patel, et al. "Idiopathic pure red cell aplasia: A case series from India." Asian Journal of Medical Sciences 14, no. 5 (2023): 253–56. http://dx.doi.org/10.3126/ajms.v14i5.49887.

Full text
Abstract:
Pure red cell aplasia (PRCA) is a rare hematologic disorder characterized by normocytic normochromic anemia with reticulocytopenia and depleted erythroid precursors. It is reported mainly from western countries. We report our experience in two patients of PRCA from India, the clinical characteristics, differential diagnosis, and their management. Our patients showed improvements following treatment with corticosteroids, blood transfusion, and/or rituximab.
APA, Harvard, Vancouver, ISO, and other styles
21

Melku, Mulugeta, Zelalem Addis, Meseret Alem, and Bamlaku Enawgaw. "Prevalence and Predictors of Maternal Anemia during Pregnancy in Gondar, Northwest Ethiopia: An Institutional Based Cross-Sectional Study." Anemia 2014 (2014): 1–9. http://dx.doi.org/10.1155/2014/108593.

Full text
Abstract:
Background. Anaemia is a global public health problem which has an eminence impact on pregnant mother. The aim of this study was to assess the prevalence and predictors of maternal anemia.Method. A cross-sectional study was conducted from March 1 to April 30, 2012, on 302 pregnant women who attended antenatal care at Gondar University Hospital. Interview-based questionnaire, clinical history, and laboratory tests were used to obtain data. Bivariate and multivariate logistic regression was used to identify predictors.Result. The prevalence of anemia was 16.6%. Majority were mild type (64%) and morphologically normocytic normochromic (76%) anemia. Anemia was high at third trimester (18.9%). Low family income (AOR [95% CI] = 3.1 [1.19, 8.33]), large family size (AOR [95% CI] = 4.14 [4.13, 10.52]),hookworminfection (AOR [95% CI] = 2.72 [1.04, 7.25]), andHIVinfection (AOR [95% CI] = 5.75 [2.40, 13.69]) were independent predictors of anemia.Conclusion. The prevalence of anemia was high; mild type and normocytic normochromic anemia was dominant. Low income, large family size,hookworminfection, and HIV infection were associated with anemia. Hence, efforts should be made for early diagnosis and management ofHIVandhookworminfection with special emphasis on those having low income and large family size.
APA, Harvard, Vancouver, ISO, and other styles
22

Banga, Vineet, and Aarushi Soota. "RBC histogram: Useful diagnostic tool in evaluating anaemia." Indian Journal of Pathology and Oncology 11, no. 2 (2024): 124–29. http://dx.doi.org/10.18231/j.ijpo.2024.028.

Full text
Abstract:
: Anaemia is a widespread public health problem, more common in developing countries. Red blood cell histogram is a vital part for evaluation and diagnosis of anaemia. Histogram can be a useful modality for arriving at the probable diagnosis of anaemia reporting in short span of time.: To observe various RBC Histogram on haematology Analyser in anaemia and analyse the usefulness of RBC Histogram to correlate with peripheral smear.: A prospective study was done in Department of Pathology of Secondary Care hospital from January 2024 to March 2024 on 300 anaemia patients. RBC Histogram were observed, analysed and correlated with peripheral smear. Out of total 300 patients, Most common anaemia is Microcytic Hypochromic (60%), Normocytic normochromic (21.33%), Dimorphic anaemia (12.33%) and macrocytic anaemia (6%). 95.5% microcytic hypochromic anaemia showed left shifted curve, 84.3% Normocytic normochromic anaemia showed normal curve, 88% macrocytic anaemia showed right shift curve. Considering the speed, reliability and less inter observer variation of the modern haematological analysers RBC histogram are important diagnostic tool for various types of anaemia and provide accurate morphological typing of anaemia in most cases hence presumptive report can be released based on RBC histogram.
APA, Harvard, Vancouver, ISO, and other styles
23

Aini, Aini, Baiq Agustin Saptiana, Pauzan Pauzan, and Ika Nurfajri Mentari. "Erythrocyte Index Profile As An Indication of Anemia Based On Morphology In Patients (Tuberculosis) Undergoing Treatment." JSN : Jurnal Sains Natural 3, no. 1 (2025): 7–13. https://doi.org/10.35746/jsn.v3i1.598.

Full text
Abstract:
Tuberculosis is an infectious disease caused by the Mycobacterium tuberculosis bacteria which usually attacks the lungs but can also attack other organs such as lymph nodes, heart and so on. Tuberculosis is transmitted through the air, from one person to another, usually through the sputum droplets of someone who has had TB. Anaemia in Tuberculosis can be caused by disruption of the erythropoiesis process by inflammatory mediators, shortening of the life span of erythrocytes, impaired iron metabolism, malabsorption, and inadequate nutrition due to low appetite. The research method used is descriptive. Where this study will describe how the erythrocyte index is in tuberculosis patients who take medication for 1 month, 2 months, 3 months, 4 months, 5 months, and 6 months of treatment. The total respondents in this study were 20 respondents, including 10 men and 10 women. Based on the results of the erythrocyte index count, the type of erythrocytes shows the number of respondents with Hypochromic Microcytic anaemia as many as 6 people, Normochromic Microcytic anaemia as many as 3 people, Hypochromic Normocytic anaemia 1 person and Normochromic Normocytic anaemia as many as 10 people.
APA, Harvard, Vancouver, ISO, and other styles
24

Ismawatie, Emma, Resi Tondho Jimat, Yulia Ratna Dewi, and Okti Purwaningsih. "GAMBARAN TIPE ANEMIA PADA IBU HAMIL BERDASARKAN NILAI INDEKS ERITROSIT DI RSIA RESTU IBU TAHUN 2022." Jurnal Farmasindo: Jurnal Penelitian dan Pengabdian Masyarakat 7, no. 1 (2024): 44–48. http://dx.doi.org/10.46808/farmasindo.v7i1.196.

Full text
Abstract:
Anemia in pregnant women is a global problem that impacts both mother and fetus. Anemia in pregnancy is associated with maternal morbidity and is an indirect cause of maternal death in the entire population of pregnant women. Classification of anemia based on the erythrocyte index value is divided into normochromic normocytic, normochromic macrocytic, hypochromic microcytic and hypochromic macrocytic anemia. The erythrocyte index values ​​are divided into Mean Corpuscular Volume (MCV), Mean Corpuscular Hemoglobin (MCH) and Mean Corpuscular Hemoglobin Concentration (MCHC). The aim of the research is to describe the types of anemia in pregnant women based on the erythrocyte index value at RSIA Restu Ibu Sragen in 2022. This research uses a quantitative descriptive research type with a retrospective approach. The research sample was 51 medical records of pregnant women who experienced anemia at RSIA Restu Ibu Sragen in January-December 2022 using purposive sampling. The materials and tools used were secondary data from laboratory examination results of pregnant women diagnosed with anemia which included hematocrit, hemoglobin, index erythrocytes (MCV, MCH, and MCHC), Microsoft Excel and SPSS Version 21 software. Data analysis used analysis univariate. The results of the study concluded that pregnant women who experienced anemia at RSIA Restu Ibu Sragen were aged 21-34 years with a third trimester pregnancy and were primigravida. Based on the erythrocyte index, normocytic anemia was normochromic in 18 people (35.3%), microcytic hypochromic anemia in 20 people (39.2%), and macrocytic hypochromic anemia in 13 people (25.5%). So it can be said that most pregnant women experience microcytic hypochromic anemia.
APA, Harvard, Vancouver, ISO, and other styles
25

Noboa Tapia, Miguel Oswaldo, Karla María Bravo Tinoco, and Santiago Andrés Tapia Mora. "Frecuencia de anemia en expuestos perinatales al VIH en el Hospital Teofilo Dávila, El Oro-Ecuador, 2018." Revista Médica del Hospital José Carrasco Arteaga 13, no. 3 (2021): 158–63. http://dx.doi.org/10.14410/2021.13.3.ao.25.

Full text
Abstract:
BACKGROUND: HIV / AIDS is one of the most significant epidemics in the world; infection in children is the result of mother- to- child transmission in most of the cases. One of the proposed prophylaxis protocols recommends the administration of antiretroviral drugs, such as zidovudine, a drug that, among its side effects, causes anemia in a large percentage of patients who receive it. The aim of this study was to determine the frequency of anemia in newborns, perinatal exposed to HIV, who received zidovudine, at Hospital “Teófilo Dávila,” El Oro- Ecuador, in 2018. METHODS: Observational, descriptive and cross-sectional study, carried out with 50 full-term neonates, delivered by C-section, exposed to HIV, with antiretroviral treatment that includes the use of zidovudine, hospitalized in the neonatology service of Hospital Teófilo Dávila, located in the city of Machala, in 2018. RESULTS: Of the entire population, 56% (n = 28) of the sample were males. The presence of anemia (hemoglobin ˂10g/dl) was demonstrated in 28 (56%) of the 50 patients in the sample, among patients with anemia 75% (n = 21) had normocytic anemia, 64% of the anemias (n = 18) were normochromic. CONCLUSION: 56% of the neonates exposed to HIV during pregnancy who received zidovudine, developed anemia; most of these anemias were normocytic and normochromic.
APA, Harvard, Vancouver, ISO, and other styles
26

Bahadur Singh, Amresh, Nitin Ranjan Gupta, and Seema Singh. "Prevalence and determinants of anemia among hospitalized patients: a cross-sectional study." International Journal of Research in Medical Sciences 13, no. 3 (2025): 1087–93. https://doi.org/10.18203/2320-6012.ijrms20250671.

Full text
Abstract:
Background: Anemia is a prevalent comorbidity among hospitalized patients, often exacerbating the burden of underlying chronic illnesses. Understanding its prevalence, severity, and determinants is critical for improving patient care and outcomes. Methods: This cross-sectional study, conducted at two hospitals in Uttar Pradesh, India, investigated anemia among 372 hospitalized patients aged 15 years and above. Sociodemographic, nutritional, and lifestyle factors were recorded using structured questionnaires, and anemia was classified based on WHO hemoglobin thresholds. Morphological subtypes were determined through hematological analysis. Logistic regression analysis identified factors associated with anemia. Results: Anemia prevalence was 64.2%, with moderate anemia being the most common (34.1%), followed by severe (15.3%) and mild anemia (14.8%). Normocytic normochromic anemia (32.8%) was the predominant type, followed by microcytic hypochromic anemia (28.2%). Significant predictors of anemia included daily alcohol consumption (AOR: 3.75, CI: 1.69-8.27), underweight BMI (AOR: 9.23, CI: 2.87-30.23), malnutrition (AOR: 2.59, CI: 1.15-5.83), and chronic kidney disease (AOR: 11.15, CI: 4.06-30.60). Conclusions: Anemia is highly prevalent among hospitalized patients, driven by chronic diseases, malnutrition, and lifestyle factors. Normocytic normochromic anemia was most common, highlighting the contribution of chronic illnesses like kidney and liver diseases. These findings emphasize the need for targeted interventions addressing nutritional support and management of chronic conditions to mitigate anemia’s burden in hospitalized populations.
APA, Harvard, Vancouver, ISO, and other styles
27

Rajkrishna, Sarkar1* Ajit Kumar Pegu2 Kuldeep Deka3 Anish Hazra4 Mohd Uveash5. "Thymectomy and Immunosuppression in Thymoma-Associated Pure Red Cell Aplasia: A Case Report in a Rare and Treatable Paraneoplastic Syndrome." International Clinical and Medical Case Reports Journal 4, no. 5 (2025): 1–5. https://doi.org/10.5281/zenodo.15364278.

Full text
Abstract:
Pure red cell aplasia (PRCA) is a rare hematological disorder characterized by normocytic normochromic anemia, severe reticulocytopenia, and a marked reduction or absence of erythroid precursors in the bone marrow. Secondary PRCA is often paraneoplastic in origin, with thymoma being a well-recognized but uncommon cause. We report the case of a 70-year-old non-diabetic, non-hypertensive female who presented with fatigue, exertional dyspnea, and palpitations. Clinical examination revealed severe pallor without lymphadenopathy or organomegaly. Laboratory workup showed profound anemia (Hb 3 g/dL), reticulocytopenia (0.2%), and a normocytic normochromic picture on peripheral smear. Bone marrow biopsy confirmed suppression of erythroid precursors, consistent with PRCA. Extensive evaluation for infectious, autoimmune, and other hematologic causes was negative. Contrast-enhanced CT thorax revealed an anterior mediastinal mass suggestive of thymoma. The patient was initiated on immunosuppressive therapy with cyclosporine and responded clinically. She subsequently underwent a successful thymectomy, with follow-up indicating hematologic recovery. This case highlights the paraneoplastic association between thymoma and PRCA, emphasizing the importance of a thorough diagnostic approach in patients presenting with unexplained anemia. Early identification and a combination of immunosuppression and surgical management can lead to favourable outcomes. This report adds to the existing body of literature supporting thymoma-associated PRCA as a rare but treatable condition.
APA, Harvard, Vancouver, ISO, and other styles
28

Khadora, Manal Mustafa, Maysa Saleh, Rawah Idres, Sura Ahmed Al-Doory, and Mahmoud Ahmed Radaideh. "Normocytic Normochromic Anemia Revealed an Early Onset Hashimoto’s Hypothyroidism in an Infant: A Case Report." Dubai Medical Journal 4, no. 4 (2021): 353–57. http://dx.doi.org/10.1159/000519439.

Full text
Abstract:
Autoimmune thyroiditis is very rare etiology of primary hypothyroidism in infancy. Hypothyroidism has a wide range of clinical presentation, from subclinical hypothyroidism to overt type. It is unclear what pathological mechanisms connect thyroid function and erythropoiesis or how thyroid disease can contribute to anemia. We report a 12-month-old infant who presented with anemia associated with early onset of overt autoimmune thyroiditis. The peculiarity of our case enables us to draw attention of physician to consider acquired hypothyroidism in the differential diagnosis of unexplained anemia even if the neonatal screening is normal and congenital hypothyroidism is a remote possibility.
APA, Harvard, Vancouver, ISO, and other styles
29

Khadora, Manal Mustafa, Maysa Saleh, Rawah Idres, Sura Ahmed Al-Doory, and Mahmoud Ahmed Radaideh. "Normocytic Normochromic Anemia Revealed an Early Onset Hashimoto’s Hypothyroidism in an Infant: A Case Report." Dubai Medical Journal 4, no. 4 (2021): 353–57. http://dx.doi.org/10.1159/000519439.

Full text
Abstract:
Autoimmune thyroiditis is very rare etiology of primary hypothyroidism in infancy. Hypothyroidism has a wide range of clinical presentation, from subclinical hypothyroidism to overt type. It is unclear what pathological mechanisms connect thyroid function and erythropoiesis or how thyroid disease can contribute to anemia. We report a 12-month-old infant who presented with anemia associated with early onset of overt autoimmune thyroiditis. The peculiarity of our case enables us to draw attention of physician to consider acquired hypothyroidism in the differential diagnosis of unexplained anemia even if the neonatal screening is normal and congenital hypothyroidism is a remote possibility.
APA, Harvard, Vancouver, ISO, and other styles
30

Anastasilakis, Athanasios D., Mattheos Savvides, Stergios A. Polyzos, Christos Georgopoulos, and Sideris Delaroudis. "Normochromic normocytic anemia in a postmenopausal woman with severe osteoporosis treated with intermittent parathyroid hormone." Journal of Bone and Mineral Metabolism 28, no. 1 (2009): 108–10. http://dx.doi.org/10.1007/s00774-009-0105-3.

Full text
APA, Harvard, Vancouver, ISO, and other styles
31

Saito, Takatoshi, Katsuyoshi Tojo, Aya Morimoto, and Naoko Tajima. "Normocytic normochromic anemia due to autonomic neuropathy in type 2 diabetic patients without severe nephropathy." Diabetes Research and Clinical Practice 70, no. 3 (2005): 239–47. http://dx.doi.org/10.1016/j.diabres.2005.04.003.

Full text
APA, Harvard, Vancouver, ISO, and other styles
32

Cakmak, Hatice Mine. "THE SIGNIFICANCE OF NEXT-GENERATION SEQUENCING IN NON-IMMUNE HEMOLYTIC ANEMIAS AMONG NORMOCHROMIC-NORMOCYTIC ANEMIAS." Hematology, Transfusion and Cell Therapy 45 (October 2023): S24—S25. http://dx.doi.org/10.1016/j.htct.2023.09.040.

Full text
APA, Harvard, Vancouver, ISO, and other styles
33

Manandhar, Seerina Adhikari, Tapas Pramanik, Krishna Chandra Devkota, and Prem Prasad Panta. "Prevalence of Anemia and Morphological Variation in RBC among COPD Patients admitted at a Tertiary Health Care Center, Kathmandu, Nepal." Nepal Medical College Journal 23, no. 4 (2021): 324–28. http://dx.doi.org/10.3126/nmcj.v23i4.42224.

Full text
Abstract:
Many studies have depicted that anemia is one of the most common co-morbidity among Chronic Obstructive Pulmonary Disease (COPD) patients. Therefore, its correction in those patients is an important aspect of the treatment protocol. Our study was designed to explore the prevalence of anemia and morphological alteration, if any, in RBC among COPD patients. The study was conducted from November 2020 to June 2021 among the COPD patients admitted in the Medical ward of Nepal Medical College Teaching Hospital. If hemoglobin level was <13gm/dl in males and <12gm/dl in females and/or hematocrit level was <39%, the patient was considered anemic. Anemia was morphologically classified following standardized procedure with RBC indices as a reference. Among the COPD patients (n=101), 40 (39.6%) were anemic, out of which 21(52.5%) was normocytic normochromic, 10 (25%) were microcytic hypochromic, 5 (12.5%) were normocytic hypochromic, 3 (7.5%) were microcytic normochromic and (2.5%) was macrocytic hyperchromic. Anisocytosis was commonly noted (25.7%) among the COPD patients with microcytosis (20.8%) and macrocytosis (4.9%) among them. Among the patients, 23.8% showed hypochromia while only 0.9% showed hyperchromia. Polycythemia was present in 24 (23.8%) of them. Inflammatory mediators and cytokines in COPD causes a compromised response of marrow cells to erythropoietin and shortens the survival of red blood cells.
APA, Harvard, Vancouver, ISO, and other styles
34

Okafor, Ifeyinwa M., Blessing E. Thompson, Mfoniso Udonkang, Patience A. Akpan, and Enosakhare A. Asemota. "Morphological classification of anaemia and neutrophil patterns in pregnant women with asymptomatic malaria parasite infection." Sokoto Journal of Medical Laboratory Science 9, no. 3 (2024): 22–31. https://doi.org/10.4314/sokjmls.v9i3.3.

Full text
Abstract:
Asymptomatic Plasmodium infection during pregnancy increases the risk of stillbirths, abortion, premature delivery, and low birth weight. It also hinders the control and prevention of malaria as infected hosts serve as silent reservoirs for the transmission of Plasmodium species in the community. This study was conducted to assess the morphological classification of anaemia and neutrophil patterns in asymptomatic malaria parasite-infected pregnant women in Calabar, Nigeria. Fifty pregnant women attending the Antenatal Clinic at the University of Calabar Teaching Hospital in Nigeria, and 50 age-matched non-pregnant women were recruited for the study. The red cell indices and neutrophil lymphocyte ratio (NLR) were determined using Mindray assay automated haematology analyser, while standard microscopy technique was used to detect malaria parasites. The MCV (79.93 ± 9.18fl) was significantly (p<0.05) higher in pregnant women with asymptomatic malaria parasite infection compared to the non-pregnant women (73.04 ± 4.10fl), while their MCH (26.54 ± 2.17pg) was seen to be significantly lower than the non-pregnant women (28.61 ± 1.67). The NLR value in this study was seen to be significantly (2.10 ± 0.76) higher in pregnant women than non-pregnant women (1.22 ± 0.51). The prevalence of anaemia amongst the pregnant women was 48% and normocytic normochromic anaemia (54.2%) was found to be the most prevalent form of anaemia in the pregnant women, followed by microcytic hypochromic anaemia (41.7%) and then macrocytic normochromic anaemia (4.1%). Pregnant women were more susceptible to the parasite, especially Plasmodium falciparum, with a mean parasite density of 692.16 ± 151.95 (parasite/μl). A strong negative correlation was seen between the malaria parasite density and the haematocrits of the pregnant women with asymptomatic malaria parasite infection. Malaria parasite density and NLR were seen to be significantly higher in pregnant women with asymptomatic malaria infection, and normocytic normochromic anaemia was the most prevalent form of anaemia.
APA, Harvard, Vancouver, ISO, and other styles
35

Varghese, Alina Mariam, S. Sankar, and Jayalakshmy P. L. "Efficacy of RBC histogram in the diagnosis of morphological types of anaemia compared with peripheral smear." International Journal of Research in Medical Sciences 11, no. 5 (2023): 1653–59. http://dx.doi.org/10.18203/2320-6012.ijrms20231331.

Full text
Abstract:
Background: Anaemia constitutes an important diagnostic and clinical category of haematological disorders. Along with peripheral smear histogram is used to interpret the abnormal RBC morphology. The present study is to find out the efficacy of RBC histogram in diagnosis of morphological types of anaemia. Methods: A total of 354 blood samples of adults >18 years, Hb <10 mg/dl included in the study conducted at Medical College, Kottayam. Peripheral smear evaluated for RBC morphology without referring to the histogram. RBC histogram from same sample analyzed separately. The results obtained, classified into 4 morphological types of anemia -Normocytic normochromic, microcytic hypochromic, macrocytic and hemolytic anemias. Sensitivity, specificity, positive predictive value, negative predictive value and accuracy were calculated. Results: The major proportion of study is in the age group of 51-70. Major morphologic type in both, is normocytic. Concordant samples for normocytic - 161, microcytic- 97, macrocytic- 7, Hemolytic- 1. Histogram show more sensitivity and less specificity for normocytic. Microcytic has less sensitivity, more specificity. Macrocytic showed >90% sensitivity and specificity. Hemolytic has less sensitivity, more specificity. Overall sensitivity is 75%. Conclusions: Histogram is efficient in detecting normocytic and microcytic anaemia. In macrocytic anaemia among 40 cases detected by histogram only 7 showed concordance because histogram may detect slight variation in morphology not appreciable on light microscopy. In haemolytic anaemia only one case detected by histogram. The discordance is due to low sample size.
APA, Harvard, Vancouver, ISO, and other styles
36

Karam, Dhauna, Sean Swiatkowski, Mamata Ravipati, and Bharat Agrawal. "Aggressive Systemic Mastocytosis in Association with Pure Red Cell Aplasia." Case Reports in Hematology 2018 (July 8, 2018): 1–5. http://dx.doi.org/10.1155/2018/6928571.

Full text
Abstract:
Aggressive systemic mastocytosis (ASM) is characterized by mast cell accumulation in systemic organs. Though ASM may be associated with other hematological disorders, the association with pure red cell aplasia (PRCA) is rare and has not been reported. Pure red cell aplasia (PRCA) is a syndrome, characterized by normochromic normocytic anemia, reticulocytopenia, and severe erythroid hypoplasia. The myeloid and megakaryocytic cell lines usually remain normal. Here, we report an unusual case of ASM, presenting in association with PRCA and the management challenges.
APA, Harvard, Vancouver, ISO, and other styles
37

Lamsal, K. S. "Clinical profile of patients with anemia." Journal of Institute of Medicine Nepal 31, no. 3 (2009): 30–33. http://dx.doi.org/10.59779/jiomnepal.405.

Full text
Abstract:
Introduction: Anemia itself is not a disease but a clinical feature of some other underlying problems and leads to hypoxia and a wide range of clinical consequences. In a tertiary center like Tribhuvan University Teaching Hospital (TUTH), many patients admitted in medical wards have low hemoglobin. The objective of this study is to determine the etiology and evaluate the different components of clinical profile of the patients having anemia in medical wards of TUTH. Methods: Patients having hemoglobin less than 10 in the medical wards of TUTH were enrolled in the study. Estimation of hemoglobin and other investigations were done in hematology lab of TUTH. Data were obtained by history taking, examination findings and investigation reports and analysis was done by statistical software SPSS 11.5v. Results: Among the 237 patients, 138 were male and 99 were female. The commonest age group was 40-49 years. The average hemoglobin was 7.8gm%, the lowest being 2.8gm%. Peripheral blood smear showed hypochromic picture in 140, macrocytic picture in 26 and the morphology was normocytic normochromic in 71 cases. Variceal bleeding leading to anemia was seen in 52, NSAID induced GI bleeding in 22 , peptic ulcer in 18, hookworm infestation in 6, nutritional iron deficiency and anemia of chronic diseases in remaining cases. Among the 26 cases having macrocytic anemia, 11 had megaloblastic changes in bone marrow examination and 6 had vitamin B 12deficiency and 5 had folate deficiency. Among the 71 patients having normocytic normochromic blood picture, 8 had hemolytic anemia, 11 had aplastic anemia and remaining were having anemia of chronic disease mainly chronic kidney disease. Regarding treatment, 84 patients were transfused blood. Out of total 237 patients included in the study, in-hospital mortality was 28. Conclusions: Anemia is associated with a variety of diseases. As chronic blood loss and iron deficiency are among the leading causes of anemia, hypochromic and microcytic picture was the predominant picture in peripheral blood smear. Among the patients having normocytic normochromic blood picture, majority were having chronic kidney disease which may be due to the fact that TUTH is a tertiary referral centre for chronic renal failure. In-hospital mortality due to anemia alone is lower in tertiary care centers, but the mortality in our study is due to associated co-morbid conditions like chronic renal failure and variceal upper GI bleeding.
APA, Harvard, Vancouver, ISO, and other styles
38

Kulkarni, Vrinda K., and Dilip U. Jadhav. "A study of anemia in primary hypothyroidism." International Journal of Advances in Medicine 4, no. 2 (2017): 383. http://dx.doi.org/10.18203/2349-3933.ijam20170522.

Full text
Abstract:
Background: The association between anemia and hypothyroidism has been recognized, although the prevalence of anemia in hypothyroid patients varies widely between studies. The main objectives were to study the prevalence, type, etiology of anemia in primary hypothyroidism and to correlate severity of anemia with severity of hypothyroidism.Methods: A case control study was carried out in a tertiary care hospital. Newly diagnosed 60 overt primary hypothyroid patients and 180 euthyroid controls were evaluated for anemia. Morphological types of anemia, their etiology were studied. Severity of anemia was correlated with that of hypothyroidism.Results: Anemia was observed in 45 patients with hypothyroidism. Symptoms due to anemia were significantly higher in cases than in the anemic controls. RBC morphology showed normocytic normochromic in 39, microcytic hypochromic in 14 and macrocytic in 7 cases. Serum iron was significantly lower in the cases than in the controls. Serum anti-TPO positivity was 63.33% in cases as compared to 10% in controls. Anemia was severe in cases with high TSH.Conclusions: The prevalence of anemia was 75% which was higher than that seen in the euthyroid controls. Hypothyroid patients were more symptomatic for anemia than the controls. Normocytic normochromic type of anemia was the most common type in our study. Autoimmunity in the form of anti-TPO positivity was detected in 69% of anemic cases. Iron deficiency was observed in the cases more than in the controls. There was a statistically significant negative correlation between TSH and hemoglobin.
APA, Harvard, Vancouver, ISO, and other styles
39

Sankar M.K., Uthaya, Raja M, and Damodaran Kumaran P. "To Study the Prevalence and Severity of Anemia in Solid Malignancy Patients." International Journal of Research and Review 9, no. 9 (2022): 316–20. http://dx.doi.org/10.52403/ijrr.20220934.

Full text
Abstract:
Background: Anemia in solid malignancy may be due to tumor-associated bleeding, hemolysis, hypersplenism, reduced production of EPO, nutritional deficiencies, bone marrow failure and toxicity associated with therapies which increases the mortality. Aim: To study the prevalence and severity of anemia in solid malignancy patients. Methods: Hospital based -cross sectional study done on patients above 18 years with solid malignancy with elevated C-reactive protein level (CRP). Sample size was 50.Complete blood count, peripheral smear and CRP were measured. Results: Among 50 patients, the overall prevalence of anemia in solid malignancy with elevated CRP was 100%. The mean hemoglobin was lower in female patients 8.2 ± 1.40 g/dl (mean±SD) compared with male patients 8.4 ± 2.01g/dl (mean±SD). 62% patients were having elevated CRP value ranges from 0.6mg/dl to 1 mg/dl with a mean hemoglobin of 8.3 ± 1.32 (mean±SD) and 38% were having CRP of more than 1mg/dl with a mean hemoglobin of 8.1 ± 1.02 (mean±SD). Among the different types of malignancy, colorectal and gynecological tract group were found to have low mean hemoglobin value of 7.8 ± 1.04 (mean±SD) and 7.9 ± 1.13 (mean±SD).Most of them were having moderate anemia (70%) and normocytic normochromic anemia (78%). Conclusion: The overall prevalence of anemia in solid malignancy patients with elevated inflammatory marker like CRP was 100%. Most of them were having moderate anemia (70%), normocytic normochromic type (78%). Keywords: Anemia, Solid malignancy, Hemoglobin.
APA, Harvard, Vancouver, ISO, and other styles
40

Kengere, Michael, Peter Kalubi, and Melvis Bernis. "Prevalence and Morphological Types of Anaemia among Severely Anaemic Children Admitted in Hospitals in Bushenyi District, Uganda." East African Journal of Health and Science 6, no. 1 (2023): 210–18. http://dx.doi.org/10.37284/eajhs.6.1.1306.

Full text
Abstract:
Severe anaemia is a major cause of paediatric hospital admissions and deaths in many African countries, especially in Sub-Saharan Africa. In resource-limited nations with poor diagnostic capacity, the morphological type of anaemia gives insight into the probable cause of anaemia. The study described the prevalence and morphological types of anaemia among severely anaemic children aged 2 months to 12 years of age admitted at three hospitals in the Bushenyi district. A cross-sectional descriptive study among 225 children aged 2 months to 12 years admitted in paediatric wards of three hospitals in Bushenyi district, Kampala International University Teaching Hospital, Comboni Hospital, and Ishaka Adventist Hospital from April 2017 to December 2017. Data was collected using a structured questionnaire, entered using Excel and analysed using STATA 2016. Proportions were used to obtain the prevalence of children with severe anaemia and the morphological types of anaemia. The prevalence of severe anaemia was 8.1%. Of this prevalence, 71.6% were under the age of five years. The morphological types of anaemia were normocytic normochromic anaemia (56.4%), microcytic hypochromic anaemia (27.1%) and macrocytic anaemia (16.4%). Severe anaemia was common among children admitted to hospitals in Bushenyi district. The majority of the children had normocytic normochromic, followed by microcytic hypochromic and macrocytic anaemia. We therefore recommend that clinicians should routinely screen and type anaemia for the proper management of children presenting with anaemia at our health facilities.
APA, Harvard, Vancouver, ISO, and other styles
41

Kaur, Dupinder, and Pooja Agarwal. "To study and analyze hematological parameters in anaemia in males." IP Journal of Diagnostic Pathology and Oncology 6, no. 2 (2021): 132–34. http://dx.doi.org/10.18231/j.jdpo.2021.028.

Full text
Abstract:
Hematological parameters like Hb (haemoglobin), TC (total count), DC (differential count), PCV (packed cell volume), MCV (mean red cell corpuscular volume) done in the automated cell counter and peripheral smear findings were studied. Observational study.Out of 250 cases, 192 i.e. 76.8% cases showed microcytic hypochromic anaemia, 30 cases i.e. 12% had normocytic hypochromic anaemia, 27 cases i.e. 10.6% had normocytic normochromic anaemia and dimorphic anaemia was seen in 02 cases i.e. 0.6% cases.Out of 250 cases, 193 i.e. 77.2% cases showed microcytosis maximally in 0-5 years age group and 57 cases i.e. 22.8% had normocytic picture. The distribution of peripheral smear (RBC size) finding with age varied significantly (p value <0.05). Iron deficiency is almost universal when dealing with this magnitude of anaemia. However, clinically speaking, many technical experts believe that to differentiate severe anaemia, a screening for other causes is desirable, all males are recommended to be screened. In the present study of pediatric cases 0-5 years age group males were most affected and prevalence was more in males as compared to females and the predominant morphological pattern was microcytic hypochromic anaemia.
APA, Harvard, Vancouver, ISO, and other styles
42

Goti, Raina, Pragnesh H. Shah, and Jay Raval. "Comparison between Automated Hematology Analyzer and Peripheral Blood Smear Examination for Assessment of Morphological Types of Anemia." GAIMS Journal of Medical Sciences 4, no. 1 (2024): 188–91. https://doi.org/10.5281/zenodo.10775031.

Full text
Abstract:
<strong>Background</strong>Anemia represents a major healthcare burden in developing country like India. Since decades peripheral blood smear has been used&nbsp;for diagnosis of anemia. Cell counter has been introduced with increasing efficacy and a decreasing cost all over the world. Aim of&nbsp;this study was to correlate morphological typing of anemia based on RBC indices and RDW obtained from automated hematology&nbsp;analyzer with PBS (Peripheral Blood Smear) and to give better approach in diagnosis of anemia and analyze their limitations. <strong>Materials and Methods</strong>This prospective study was undertaken at Sir T hospital, Bhavnagar comprising of total 300 cases of anemia over a period of 4&nbsp;months between July to October, 2021. Anemia typing was done by NIHONKODEN 9100 hematology analyzer and peripheral&nbsp;blood smear. <strong>Results</strong>Out of 300 cases, 265 cases of anemia typed by RBC indices and RDW obtained from hematology analyzer were correct. 35 cases&nbsp;needed blood smear examination for correct typing of anemia. Microcytic hypochromic anemia was the most common&nbsp;morphological type of anemia followed by normocytic normochromic anemia. Anemia was found to be more common in females.&nbsp;Microcytic hypochromic anemia and normocytic normochromic anemia was the most common type in females and males&nbsp;respectively. <strong>Conclusions</strong>PBS examination remains the gold standard test for morphological typing of anemia. With new advances in hematology analyzer&nbsp;typing of anemia can be done with indices and RDW but PBS confirmation is must. Both the methods should be used complementary&nbsp;to each other for better diagnostic accuracy.
APA, Harvard, Vancouver, ISO, and other styles
43

Tukira, Alex Jekson, Lucia Sincu Gunawan, and Edy Prasetya. "Erythrocyte Morphology in Women of Reproductive Age (WORA) with Anemia." Biomedika 13, no. 1 (2020): 83–91. http://dx.doi.org/10.31001/biomedika.v13i1.613.

Full text
Abstract:
Anemia is a decrease in the number of erythrocytes in the blood circulation or the level of hemoglobin that is less than normal. The three major body mechanisms that cause anemia are excessive destruction of erythrocytes, blood loss, and decreased erythrocyte production. Based on the Basic Health Research (Riskesdas) in 2013, the prevalence of anemic women of reproductive age (WORA) aged 15-44 years in Indonesia was 35.3%. Anemia is classified based on the morphology of erythrocytes, including hypochromic microcytic, normocytic normochromic, and macrocytic. Erythrocyte morphology can be observed using peripheral blood smear examination. The objective of this study was to determine the morphology of erythrocytes in anemic women of reproductive age. This study belongs to descriptive research. The population of the study was 136 women of reproductive age, covering the students of D-IV in Medical Laboratory Technology at Setia Budi University. Forty-one respondents suffering from anemia were taken using a purposive sampling technique. The types of anemia were determined with examination using an Easy Touch hemoglobinometer with the Hb level of less than 12g/dL. Preparation of peripheral blood smear examination using EDTA venous blood and stained with Giemsa. Microscopic examination was performed with 1000x objective magnification. The peripheral blood smear reading showed the erythrocyte morphology that includes normocytic normochromic (38 samples or 93%), microcytic hypochromic (three samples or 7%), and poikilocytosis consisting of teardrop cells, target cells, ellipstocytes, and stomatocytes (five samples or 18%). Further study is required to investigate the correlation of erythrocyte index and peripheral blood smear in anemia.
APA, Harvard, Vancouver, ISO, and other styles
44

Prasetya, Hieronymus Rayi, Sistiyono Sistiyono, and Maria Elisabeth Enjel Naur. "Gambaran Anemia pada Lanjut Usia di Panti Sosial Tresna Werdha Abiyoso Yogyakarta Tahun 2013." Journal of Health 1, no. 1 (2014): 23. http://dx.doi.org/10.30590/vol1-no1-p23-28.

Full text
Abstract:
Background: Anemia is a main health problem of elderly. The aging process causes many psychological changes in nearly all body systems of elderly that causes many kinds of processes of nutrient absorptions in the body disturbed. There is an opinion says that generally elderly has lower hemoglobin levels compared to the younger people. Other research showed that elderly often suffered from calorie and protein malnutrition and micronutrient. It happened because the HCL and pepsin secretion was reduced. Consequently, the absorption of Vitamin B12 and iron decreased that causes Anemia.&#x0D; Method: It was a descriptive analysis with laboratory tests. The sample of this research was 60 year-old and older patients in TresnaWerdhaAbiyoso Nursing Home Yogyakarta. There were 96 patients. The data of research results were analyzed descriptively and presented in the forms of tables and graphs.&#x0D; Results: Of the 96 old patients, there were 31 patients suffered from anemia that consisted of 27 patients with mild anemia and 10 patients with moderate anemia. Based on the morphology of erythrocytes in elderly, there were two kinds of anemia. They were normocytic-normochromic anemia with 84 patients and microcytic-hypochromic anemia with 12 patients.&#x0D; Conclusion: The description of anemia in elderly who stayed in TresnaWerdhaAbiyoso Nursing Home Yogyakarta showed that 32.29% of the elderly suffered from anemia. 72.97% suffered from mild anemia. 27.03% suffered from moderate anemia. The anemia classifications based on morphology in elderly in Tresna Werdha Abiyoso Nursing Home Yogyakarta were 87.5% normocytic-normochromic anemia and 12.5% microcytic-hypochromic anemia.
APA, Harvard, Vancouver, ISO, and other styles
45

Patil, Omkareshwar, Sukesh ., and Jayaprakash CS. "To Study the Pattern of Anemia in Type 2 Diabetes Mellitus in Elderly Hospitalized Patients." International Journal of Science and Healthcare Research 8, no. 4 (2023): 203–8. http://dx.doi.org/10.52403/ijshr.20230429.

Full text
Abstract:
Background: Anemia found in diabetes patients is often unrecognized like many other chronic diseases. Anemia is more common in people with diabetes due to a variety of causes. The aim of this study was to determine the severity and morphological types of anemia among type II diabetic elderly hospitalized patients. Methodology: The present study was a hospital based cross sectional study conducted at Father Muller Medical Collage Hospital, Mangalore Karnataka over a period of 6 months. The cases for the study included 129 elderly patients with having Type 2 Diabetes Mellitus (DM). 129 Hospitalized elderly patients over the age of 60 years who were confirmed to have type 2 DM patient’s demographic data and the blood samples are analyzed for Complete blood count, Peripheral smear for type of anemia, Random blood glucose, Glycated hemoglobin. Result: A total 129 Hospitalized elderly type 2 DM patients were included in the study. Out of 129 subjects, 55.03% were males and 44.97% were females. Of these 24.8% patients had mild anemia, 63.56% had moderate anemia and 11.64% had severe anemia according to clinical degree of anemia based on hemoglobin level. 67.76% patients had microcytic hypochromic anemia, and 30.24% patients had normocytic normochromic anemia. The prevalence of type 2DM is high in male than the female population. Conclusion: The study results exhibit a higher level of the prevalence of anemia in Type 2 DM subjects. The findings of our study suggest that moderate degree of anemia is a common finding, and morphologically, the leading type of anemia was normocytic normochromic anemia. Keywords: Diabetes Mellitus, Anemia, Hemoglobin, Hyperglycemia.
APA, Harvard, Vancouver, ISO, and other styles
46

Lucky, Sriwastwa, Jaiswal C.P., and Kumar Sunil. "Hematological Parameters versus Peripheral Smear in Anemic Patients: A Comparative Study." International Journal of Current Pharmaceutical Review and Research 15, no. 06 (2023): 392–98. https://doi.org/10.5281/zenodo.12606070.

Full text
Abstract:
AbstractAim: The present study was designed to find out the association between cell countergenerated hematological parameters and peripheral smear findings in the diagnosis of anemiaMethods: This study was carried out in Department of Pathology, Nalanda Medical Collegeand Hospital, Patna, Bihar, India for 12 months. 100 patients with low Hb level withreference to age and sex were selected for the comparison of PS findings with that of cellcounter parameters.Results: Anemia was more common in our study was age group more than 60 years (32 outof 100 cases, 32%) followed by between 41 to 50 years (26 out of 100, 26%). In males,normocytic normochromic anemia was more common (38 out of 52 cases,) and in females,microcytic hypochromic anemia was more common (34 out of 40 cases). Out of 40 cases ofmicrocytic hypochromic anemia 33 cases showed low MCV but 6 cases showed normalMCV. When compared, the anemia diagnosed based on MCV values and by manualexamination there was a significant difference. Out of 52 cases of normocytic normochromicanemia, 46 cases showed normal MCV level. 37 cases of Microcytic hypochromic anemiahad high RDW which was normally expected but 26 cases of Normocytic normochromicanemia showed raised RDW.Conclusion: Despite all the advances in laboratory sciences, peripheral smear examinationremains an important diagnostic tool in diagnosis of anemia.
APA, Harvard, Vancouver, ISO, and other styles
47

Dr., Mihirkumar J. Bhalodia. "Correlation between Morphological Typing of Anemia Based On RBC Indices and RDW Obtained from Sysmex KX-21, an Automated Hematological Analyser with Peripheral Blood Smear Examination." International Journal of Medical and Pharmaceutical Research 4, no. 4 (2023): 291–97. https://doi.org/10.5281/zenodo.8286084.

Full text
Abstract:
<strong>INTRODUCTION</strong> - Anemia affects millions of people globally. Once anemia is diagnosed clinically, a morphological typing of anemia pathologically helps the treating physician to come up to the cause of anemia. In the new era of laboratory diagnostics, the automated hematology analyzers give accurate results for the RBC indices and hence have replaced the manual methods in the majority. The expertise needed to see the peripheral blood smear is unquestionably far more than that needed to run the analyzers. Moreover, in morphological typing of anemia based on peripheral blood smear examination, there is intra and inter observer variation. Further peripheral blood smear review performed by pathologists hardly ever provide unique information and provide incremental helpful information in few of the cases. Hence, the aim of the present study was to correlate morphological typing of anemia based on RBC indices and RDW obtained from KX-21, an 3 &ndash;part automated hematology analyzer with peripheral blood smear evaluation and to discover if the rate of manual peripheral blood smear review in cases of anemia already morphologically typed on automated analyzer can be reduced. &nbsp; <strong>METHODS</strong> - A total of 1100 cases of anemia were studied over a period of five years between January 2017 to December 2021 at Central Diagnostic Laboratory, Dhiraj hospital, Department of Pathology, Smt. B. K. Shah Medical Institute &amp; Research Centre, Piparia, Vadodara. Anemia typing was done by two methods &ndash; to start with using RBC indices &amp; RDW only. Subsequently on peripheral blood smear examination. The results were then correlated and analyzed. &nbsp; <strong>RESULTS</strong> - All the cases were typed as Microcytic Hypochromic Anemia with normal and raised RDW, Macrocytic Anemia and Normocytic Normochromic Anemia with normal RDW (91.82 %) on RBC indices with RDW alone. Then all these were confirmed as the same by peripheral blood smear examination. However all cases typed as Normocytic Normochromic Anemia with raised RDW (8.18 %) on RBC indices with RDW alone were typed as either Dimorphic Anemia or Microcytic Hypochromic Anemia with polychromasia on subsequent peripheral blood smear examination. &nbsp; <strong>CONCLUSION</strong> - Morphological typing of anemia in cases of Microcytic hypochromic anemia with normal and raised RDW and Macrocytic anemia using RBC indices and RDW from 3 part automated hematology analyzer shows very high specificity and high sensitivity. In cases of Normocytic normochromic anemia, the cases with normal RDW showed high specificity and sensitivity but the cases with high RDW were wrongly typed on indices alone and had a low sensitivity and specificity signifying that additional peripheral blood smear examination as an extremely essential tool in morphological typing of anemia.
APA, Harvard, Vancouver, ISO, and other styles
48

Baker, Dale C., Stephen D. Gaunt, and Shirley S. Babin. "Anemia of inflammation in dogs infected with Ehrlichia platys." American Journal of Veterinary Research 49, no. 7 (1988): 1014–16. https://doi.org/10.2460/ajvr.1988.49.07.1014.

Full text
Abstract:
SUMMARY Ten adult male dogs were inoculated with Ehrlichia platys, and blood samples were collected throughout the infection to evaluate the hematologic changes with respect to serum biochemical analytes. All dogs developed a mild, normocytic, normochromic anemia by postinoculation day 7, with significantly (P &lt; 0.05) decreased serum iron concentration and total iron-binding capacity. Stainable bone marrow iron appeared normal or increased throughout the infection. By postinoculation day 31, the pcv was not significantly different from the pretreatment value. All dogs became hypergammaglobulinemic, leukopenic, hypoalbuminemic, and hypocalcemic during the infection. These findings were compatible with the syndrome of anemia of inflammation.
APA, Harvard, Vancouver, ISO, and other styles
49

Żórawski, M., B. Musiałowska, M. Rudzińska, E. Koc-Żórawska, and J. S. Małyszko. "Anaemia in chronic kidney disease- new treatment options." Progress in Health Sciences 8, no. 2 (2018): 210–14. http://dx.doi.org/10.5604/01.3001.0012.8349.

Full text
Abstract:
In recent years anaemia has been recognized as one of the most specific and evident manifestations of chronic renal failure. In the majority of cases, renal anaemia is normocytic and normochromic with normal cellularity of bone marrow. Multiple factors contribute to the molecular origins of the anaemia of chronic kidney disease. Within those factors, the disturbances in the production of erythropoietin have the greatest impact on the disease pathogenesis. However, other components such as shortened erythrocyte survival, blood loss, iron or other nutritional deficiencies, hemolysis, the presence of uremic inhibitors of erythropoiesis among others can also significantly contribute to the occurrence of anaemia.
APA, Harvard, Vancouver, ISO, and other styles
50

Verma, Shubhangi, and Sohail Sheikh. "Prevalence of anaemia and its correlation with glycosylated haemoglobin among patients with type 2 diabetes mellitus: an observational study." International Journal of Advances in Medicine 8, no. 6 (2021): 800. http://dx.doi.org/10.18203/2349-3933.ijam20212102.

Full text
Abstract:
Background: Anaemia and type 2 diabetes mellitus are two sides of a coin affecting the quality of life of the patients. Anaemia associated with diabetic status of the patients disturbs the exercise capacity, increases fatigue, anorexia, depression, cognitive dysfunction and decreased libido. Hence, we conducted a study to find the prevalence of anaemia among patients with type 2 diabetic patients and its correlation with glycosylated haemoglobin.Methods: An observational study was conducted in the department of medicine in a tertiary care hospital in Maharashtra. The data was collected from patients with type 2 diabetes attending the outpatient department during a span of 5 months (September 2020 to February 2021). The patients with pre-existing hypertension, chronic renal failure, congestive cardiac failure, stroke and other haematological disorders were excluded from the study. Patients on hormonal therapy, pregnant and lactating patients were also excluded from the study. Prior to the start of the study necessary permissions were taken from the institutional ethics committee. Relevant statistics were used to analyse the data.Results: The prevalence of anaemia in the present study was 45 (56.25%). Among these 45 patients 37 patients had normocytic normochromic anaemia, 6 cases of microcytic hypochromic anaemia and 2 cases of macrocytic anaemia. The mean haemoglobin levels among patients with Hba1c more than 7% was 9.7±1.12 and among Hba1c less than 7% was 12. 23±1.08 and this difference was statistically significant.Conclusions: About half of the patients were anaemic in the present study. Normochromic normocytic anaemia was the most common type of anaemia. There was significant association with levels of anaemia with Hb1ac in the present study.
APA, Harvard, Vancouver, ISO, and other styles
We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!