Academic literature on the topic 'Normotension'

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Journal articles on the topic "Normotension"

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Seyde, W. C., and D. E. Longnecker. "NORMOTENSION VERSUS HYPERTENSION." Anesthesiology 63, Supplement (1985): A13. http://dx.doi.org/10.1097/00000542-198509001-00013.

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Brunner, M. J., and M. D. Kligman. "Rapid resetting of baroreflexes in hypertensive dogs." American Journal of Physiology-Heart and Circulatory Physiology 262, no. 5 (1992): H1508—H1514. http://dx.doi.org/10.1152/ajpheart.1992.262.5.h1508.

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The hypothesis tested was that the rapid resetting of the arterial baroreflex control of arterial pressure in normotension could be demonstrated in experimental hypertension. After the development of experimental hypertension (using a bilateral renal wrap technique), rapid resetting of arterial pressure and heart rate (HR) was acutely assessed under pentobarbital sodium anesthesia in hypertensive and normotensive vagotomized dogs. The carotid sinus area was isolated and perfused at controlled carotid sinus pressures (CSPs). Baroreflex response [mean arterial pressure (MAP) and HR] curves were measured after three carotid sinus conditioning pressures (50, 125, and 200 mmHg) were applied. For the MAP response, the CSPo (CSP at point of maximum reflex gain) increased significantly to the same extent in both groups with increasing conditioning pressures (with 22.2 and 16.7% resetting in the normotensive group, and 20.3 and 14.2% resetting in the hypertensive group). We conclude that short-term adjustments to changes in prevailing pressure (rapid resetting) occur in the arterial pressure response in experimental hypertension to the same extent seen in normotension.
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Sanz, Jesús, María Paz García‐Vera, Inés Magán, Regina Espinosa, and María Fortún. "Differences in personality between sustained hypertension, isolated clinic hypertension and normotension." European Journal of Personality 21, no. 2 (2007): 209–24. http://dx.doi.org/10.1002/per.605.

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The aim of this study was to determine whether there are differences in personality between hypertension and normotension. Forty‐two male patients with essential hypertension were divided into two groups after self‐assessment of blood pressure, 18 with sustained hypertension and 24 with isolated clinic (white coat) hypertension, and were compared with 25 men with normotension on Spielberger's State‐Trait Anxiety Inventory and the Jenkins Activity Survey. In line with hypotheses, the sustained hypertensive group showed higher levels of trait anxiety, Type A behaviour pattern, and hard‐driving behaviours/competitiveness than the normotensive group, whereas isolated clinic hypertensives occupied an intermediate position between those two groups. Results provide support to the hypothesised relationship between personality and hypertension and stress the need of distinguishing sustained hypertension from isolated clinic hypertension. Copyright © 2006 John Wiley & Sons, Ltd.
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Harper, Alexander A., Julian P. L. Davis, and Alan R. Chipperfield. "Activation of Two Inward Chloride Transport Systems in Rat Femoral Arterial Smooth Muscle in Deoxycorticosterone Acetate/Salt Hypertension." Clinical Science 93, no. 4 (1997): 295–98. http://dx.doi.org/10.1042/cs0930295.

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1. Intracellular [Cl−] ([Cl−]i) was measured with ion-selective microelectrodes in rat femoral arterial smooth muscle in normotensive controls and after the induction of deoxycorticosterone acetate/salt hypertension. 2. Linear regression of [Cl−]i and time after the induction of hypertension showed good correlation (r = 0.96) for 5–6 weeks, as [Cl−]i increased from 30 ± 1 mmol/l (mean ± SD, n = 16), to 49 ± 2 mmol/l (n = 9, P < 0.0001). 3. Arterial systolic blood pressure also increased linearly (r = 0.97) for 5–6 weeks as hypertension developed from 122 ± 1 mmHg (n = 20) to 187 ± 7 mmHg (n = 14): there was consequently a linear relationship between [Cl−]i and arterial systolic blood pressure (r = 0.96). 4. The increase in [Cl−]i was partly because Na+−K+−Cl− co-transport activity, estimated from the fall in [Cl−]i caused by bumetanide, was greater in hypertension (18 mmol/l) than in normotension (10 mmol/l). This finding, and the depolarization of the membrane potential in hypertension (−56 ± 3 mV compared with −64 ± 4 mV in normotension; P < 0.0001), confirms previous studies. 5. The increase in [Cl−]i was also partly due to greater activity of an Na+- and HCO3−-independent, acetazolamide-sensitive inward Cl− transport system; thus acetazolamide reduced [Cl−]i by 7 mmol/l in normotension and by 16 mmol/l in hypertension. 6. In Cl−-free media, the membrane potential in normotension (−59 ± 5 mV) was not significantly different from that in hypertension (−60 ± 4 mV). 7. The role of [Cl−]i in the depolarization of the membrane potential in hypertension is discussed.
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de Leeuw, Peter W., and Abraham A. Kroon. "A sluice to normotension?" Journal of Hypertension 36, no. 12 (2018): 2314–15. http://dx.doi.org/10.1097/hjh.0000000000001926.

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Jannah, Mifthahul, Delmi Sulastri, and Yuniar Lestari. "Perbedaan Asupan Natrium Dan Kalium Pada Penderita Hipertensi Dan Normotensi Masyarakat Etnik Minangkabau di Kota Padang." Jurnal Kesehatan Andalas 2, no. 3 (2013): 132. http://dx.doi.org/10.25077/jka.v2i3.148.

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AbstrakHipertensi adalah peningkatan tekanan darah sistolik ≥140 mmHg atau tekanan darah diastolik ≥90 mmHg. Penyakit ini disebut juga the silent killer karena tidak menunjukkan gejala. Salah satu faktor penyebab hipertensi adalah tingginya asupan natrium dan rendahnya asupan kalium. Rasio Na:K yang dianjurkan adalah 1:1. Penelitian ini bertujuan untuk mengetahui perbedaan asupan natrium dan kalium pada penderita hipertensi dan normotensi masyararakat Etnik Minangkabau di Kota Padang. Desain penelitian study comparative dengan pendekatan cross sectional. Populasi adalah masyarakat etnik Minangkabau usia 35-65 tahun di 4 kecamatan terpilih di Kota Padang. Jumlah sampel sebanyak 254 orang yang diambil secara multi stage random sampling. Data responden dikumpulkan dengan kuisioner, tekanan darah dengan sphygmomanometer, asupan natrium dan kalium dengan food frequency questionnaire (FFQ). Data dianalisis dengan uji Chi-Square pada p-value< 0,05 dan uji beda rata-rata dengan metode Independent sample t-test. Hasil penelitian didapatkan rerata sistolik pada normotensi 118,87 mmHg dan diastolik pada normotensi 76,74 mmHg. Rerata sistolik pada hipertensi 154,50 mmHg dan diastolik pada hipertensi 90,59 mmHg. Tidak ditemukan adanya hubungan antara asupan natrium, asupan kalium dan rasio asupan Na:K dengan tekanan darah. Kesimpulan penelitian ini ialah tidak ada hubungan antara asupan natrium, asupan kalium dan rasio asupan Na:K dengan tekanan darah.Kata kunci: natrium, kalium, rasio Na:K, tekanan darah, normotensi, hipertensiAbstractHypertension is the blood pressure escalation of systolic ≥140 mmHg or diastolic ≥90 mmHg. This is also called the silent killer because it does not show any symptoms. One of the factors causes hypertension is high sodium and low potassium intakes. The ratio of Na:K that is suggested is 1:1. The objective of this study is to know the differences sodium and potassium intake in patients hypertension and normotension on Minangkabau Ethnic society in Padang. The design of this research was comparative study with the cross sectional approach. The population were taken from Minangkabau ethnic age 35-65 years old in four selected districts in Padang. The total sample of 254 people were taken by multi-stage random sampling. The data were collected by questionnaire of respondents, sphygmomanometer blood pressure, sodium and potassium intakes with a Food Frequency Questionnaire (FFQ). The data was analyzed by Chi-Square test at p-value <0.05 and an average of different test methods Independent sample t-test. The result showed that average systolic of normotensive was 118.87 mmHg and diastolic of normotensive was 76.74 mmHg. The average sistolic of hypertension was 154.50 mmHg and diastolic of hypertension was 90.59 mmHg. The conclusion of this study is that there is no significant correlation between the sodium intake, potassium intake and the ratio of Na: K with the blood pressure.Keywords: sodium, potassium, ratio of Na:K, blood pressure, normotension, hypertension
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Funder, John W. "Aldosterone, Normotension, and Diastolic Dysfunction." Journal of Clinical Endocrinology & Metabolism 90, no. 9 (2005): 5500–5501. http://dx.doi.org/10.1210/jc.2005-1613.

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Leffler, C. W., and D. W. Busija. "Prostanoids and pial arteriolar diameter in hypotensive newborn pigs." American Journal of Physiology-Heart and Circulatory Physiology 252, no. 4 (1987): H687—H691. http://dx.doi.org/10.1152/ajpheart.1987.252.4.h687.

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Effects of hypotensive hemorrhage on pial arteriolar diameter and cortical subarachnoid fluid prostanoid concentrations were investigated in newborn pigs. Chloralose-anesthetized piglets were equipped with closed cranial windows over the parietal cortex for observation of pial arterioles and collection of cerebrospinal fluid (CSF) passing over the cerebral surface (cortical subarachnoid CSF). Prostanoids in the CSF were determined by radioimmunoassay. Measurements of pial arterioles were made during normotension (63 +/- 4 mmHg) and hypotension (28 +/- 3 mmHg). Hypotension caused pial arteriolar diameters to increase from 162 +/- 22 to 193 +/- 22 microns. During normotension, the cortical subarachnoid prostanoid concentrations were (in ng/ml) prostaglandin E2 (PGE2) 2.6 +/- 0.7, 6-ketoprostaglandin F1 alpha (6-keto-PGF1 alpha) 1.7 +/- 0.4, thromboxane B2 (TXB2) 0.25 +/- 0.02. Hypotension caused 6-keto-PGF1 alpha to increase 245 +/- 104% and PGE2 to increase 132 +/- 38%. TXB2 increased slightly (37 +/- 21%). Topical application of PGE2 and prostacyclin caused marked dilation of pial arterioles. Treatment of hypotensive newborn pigs with indomethacin caused constriction of pial arterioles to diameters not significantly different from the normotensive diameters. These data are consistent with the hypothesis that the prostanoid system contributes to the maintenance of cerebral blood flow during hypotension in piglets.
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Hatt, Andrew. "Phentolamine continuous infusion in a pediatric patient with uncontrolled hypertension." American Journal of Health-System Pharmacy 78, no. 13 (2021): 1195–99. http://dx.doi.org/10.1093/ajhp/zxab133.

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Abstract Purpose A case of uncontrolled hypertension nonresponsive to traditional pharmacologic management in a pediatric patient with a ventricular assist device awaiting a heart transplant is reported. Summary A 4-month-old male in heart failure was experiencing uncontrolled hypertension. Because of a lack of hemodynamic stability, he was unable to be listed as a heart transplant candidate. He received multiple antihypertensive agents (calcium channel blockers, β-blockers, and direct-acting vasodilators) as both intermittent and continuous infusions over the course of several days without achieving normotension. The decision was then made to administer intravenous phentolamine as a continuous infusion to pursue a different mechanism than with traditional antihypertensive agents to achieve hemodynamic stability. Within 8 hours of initiation of the continuous phentolamine infusion, the patient became normotensive and was listed for a heart transplant. The continuous phentolamine infusion was administered over the next 4 days to maintain normotension, and on day 4 the patient underwent successful orthotopic heart transplantation. Conclusion A 4-month-old male in heart failure with a ventricular assist device, experiencing uncontrolled hypertension nonresponsive to traditional pharmacologic management, was successfully treated with a continuous intravenous infusion of phentolamine.
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Wang, Jian-Bing, Qiu-Chi Huang, Shu-Chang Hu, et al. "Baseline and longitudinal change in blood pressure and mortality in a Chinese cohort." Journal of Epidemiology and Community Health 72, no. 12 (2018): 1083–90. http://dx.doi.org/10.1136/jech-2018-211050.

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BackgroundA J-curve association has been demonstrated for blood pressure (BP) and all-cause mortality, but data on longitudinal change of BP and mortality in Chinese population are limited.MethodsWe performed a retrospective cohort study to examine the association between BP (at baseline and longitudinal change) and risk of mortality in Yinzhou District, Ningbo, China, based on the Yinzhou Health Information System. At baseline, a total of 181 352 subjects aged over 18 years with at least one BP examination record were recruited through the Yinzhou Health Information System. The final analysis was restricted to 168 061 participants after exclusion of outliers of BP.ResultsA U-shaped association was observed for BP at baseline and risk of total and cardiovascular mortality. When compared with normotensive participants, patients with hypotension (HRs=1.51, 95% CI 1.21 to 1.88) and stage 3 hypertension (1.28, 95% CI 1.09 to 1.50) had an increased risk of all-cause mortality. Relative to stable BP of normotension, having a rise in BP from normotension to hypertension or from prehypertension to hypertension both conferred an increased risk of total and cardiovascular mortality (total: 1.39 (95% 1.10 to 1.75) and 1.40 (95% 1.15 to 1.69); cardiovascular: 2.22 (95% CI 1.35 to 3.65) and 1.89 (95% CI 1.20 to 2.96), respectively).ConclusionsOur findings emphasise that hypotension and stage 3 hypertension were associated with an increased risk of all-cause mortality. Longitudinal change from normotensive or prehypertensive levels to 140/90 mm Hg or higher could increase the risk of total and cardiovascular mortality.
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Dissertations / Theses on the topic "Normotension"

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Guillard, Frédérique. "Devenir de 40 sujets jugés normotendus a l'issue d'un bilan hospitalier d'hypertension : étude cas-contrôle." Lyon 1, 1993. http://www.theses.fr/1993LYO1201B.

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Exner, Cécile. "Hyperaldostéronisme primaire par adénome de Conn et normotension : à propos d'un cas." Bordeaux 2, 1995. http://www.theses.fr/1995BOR2M061.

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Campos, Débora Ribeiro. "Avaliação do efeito vascular do diterpeno esclareol em ratos normotensos e hipertensos." Universidade de São Paulo, 2016. http://www.teses.usp.br/teses/disponiveis/17/17137/tde-27072016-152727/.

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INTRODUÇÃO. A hipertensão arterial sistêmica é uma doença cardiovascular comum que afeta cerca de 50 milhões de pessoas nos EUA, e um número proporcional a este no Brasil. Muitos estudos têm mostrado que diversas classes de diterpenóides exercem efeito significante sobre o sistema cardiovascular. Esses estudos apontam essa classe de metabólitos como uma fonte promissora de protótipos para o desenvolvimento de novos agentes na terapêutica cardiovascular. OBJETIVO. O presente estudo foi delineado de forma a investigar os mecanismos envolvidos no efeito cardiovascular (in vitro e in vivo) do diterpeno esclareol em ratos normotensos e hipertensos. MATERIAL E MÉTODOS. Foram utilizados ratos Wistar machos, pesando em média 250 - 300g provenientes do Biotério Central do Campus de Ribeirão Preto, Universidade de São Paulo (USP). Os animais foram acondicionados no Biotério do Departamento de Cirurgia e Anatomia, em ambiente com temperatura (22-25ºC) e ciclo claro/escuro (12:12 horas) controlados. Para a indução da hipertensão utilizou-se o modelo 2 rins - 1 clipe (artéria renal esquerda). A pressão arterial não invasiva da cauda foi avaliada utilizando-se um manguito, conectado a um sensor para registro de pressão arterial sistólica (Kent Scientific Corporation, Connecticut, USA). A monitorização da pressão arterial média foi realizada utilizando-se o MP System 100 A (BioPac System, Inc., Santa Barbara, CA, USA). A reatividade vascular in vitro foi estudada pela avaliação de curvas concentração-resposta para esclareol construídas a partir do registro de forças isométricas obtidas em anéis de aorta, com ou sem endotélio, pré-contraídos com Phe 10-7M em câmaras de órgãos (\"organ chambers\"). As dosagens indiretas de NO plasmático foram realizadas pela determinação dos níveis séricos de nitrito e nitrato utilizando-se o Sievers NOAnalizer 280i (Sievers, Boulder, CO, E.U.A.). Análise de variância de uma ou duas vias (ANOVA), seguida pelo pós-teste de Bonferroni foram realizadas para detectar possíveis diferenças entre os valores em estudo. P<0,05 foi considerado significativo. RESULTADOS. A análise do efeito do Esclareol sobre a ?PAS mostrou que, em ambos os grupos, houve uma importante redução da ?PAS. Os inibidores de óxido nítrico sintase e guanilato ciclase foram tão eficientes quanto a retirada do endotélio, em inibir o relaxamento induzido pelo esclareol. A análise das dosagens do NO plasmático mostrou que não houve diferença significante entre os grupos. CONCLUSÃO. A partir dos dados obtidos no presente estudo, conclui-se que o esclareol mostrou-se promissor quanto aos seus efeitos vasodilatadores, tanto in vivo quanto in vitro. Apesar disso, o esclareol não promoveu alterações do NO, possivelmente devido ao método utilizado
INTRODUCTION. High Blood Pressure is a common cardiovascular disease that affects about 50 million people in the US, and a proportionate number to this in Brazil. Many studies have shown that many diterpenoid classes exert significant effect on the cardiovascular system. These studies suggest these metabolites class as a promising source prototype for the development of new agents in the cardiovascular therapy. OBJECTIVE. This study was designed to investigate the mechanisms involved in cardiovascular effect (in vitro and in vivo) of diterpene esclareol in normotensive and hypertensive rats. MATERIAL AND METHODS. Male Wistar rats were used, weighing an average of 250 - 300g from the Central Animal Facility of the Campus of Ribeirão Preto, University of São Paulo (USP). The animals were kept in the animal house of the Department of Surgery and Anatomy in temperature environment (22-25ºC) and light / dark cycle (12:12 hours) controlled. For the induction of hypertension, the model was used two kidney - one clip (left renal artery). The tail noninvasive blood pressure was measured using a cuff, connected to a sensor for systolic arterial blood pressure ((Kent Scientific Corporation, Connecticut, USA). The monitoring of mean arterial blood pressure was measured using MP System 100 A (BioPac System, Inc., Santa Barbara, CA, USA). The in vitro vascular reactivity was evaluated by measuring concentration-response curves for sclareol built from the record of isometric forces obtained in aortic rings with or without endothelium precontracted with Phe 10-7M in organ chambers. The indirect plasma measurements of NO were carried out by determination of serum levels of nitrite and nitrate using the Sievers NOAnalizer 280i (Sievers, Boulder, CO, USA). One or two-way analysis of variance (ANOVA) followed by Bonferroni posttests were performed to detect possible differences between the values in the study. P <0.05 was considered significant. RESULTS. The analysis of the effect of Esclareol on ?PAS showed that there was a significant reduction in ?PAS in both groups. The nitric oxide synthase and soluble guanylate cyclase inhibitors were as efficient as the removal of endothelium, to inhibit relaxation induced by the sclareol. Analysis of the strengths of plasmatic showed no significant difference between groups. CONCLUSION. From the data obtained in this study, it is concluded that the sclareol showed promise as to their vasodilator effects, both in vivo and in-vitro. Nevertheless, the sclareol showed no change of NO, possibly due to the method used
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Burgi, Katia. "Tirosina hidroxilase como marcador da atividade simpática em artérias musculares esqueléticas e renais de ratos normotensos: efeitos do treinamento fisico." Universidade de São Paulo, 2007. http://www.teses.usp.br/teses/disponiveis/42/42137/tde-19102007-122123/.

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Apesar de não alterar a pressão de normotensos, o treinamento físico (T) promove importantes ajustes periféricos e adapatações centrais do controle cardiovascular mediados pelo vago e simpático. Neste trabalho investigamos os efeitos do T (55% da capacidade máxima) sobre a inervação simpática vascular para os territórios muscular esquelético (locomotor e não locomotor) e renal e adrenais, através de imunohistoquimica e Western Blot para Tirosina-Hidroxilase (TH). T aumentou a capacidade física (+0,07±0,06 Km/h) e reduziu a FC (de 327±7 para 308±10 bpm), sem alterar a PA (126mmHg) e a estrutura de arteriolas dos diferentes territórios. T também determinou redução na imunoreatividade para TH nos músculos locomotores (-48%, p<0,05), sem alterações nos não locomotores e rins. A noradrenalina na artéria femoral (HPLC) encontrava-se reduzida após T. Nenhuma alteração foi detectada nas catecolaminas adrenais.Os dados indicam, que o T não altera as catecolaminas plasmáticas, mas reduz a atividade simpática vascular em normotensos, sendo este efeito tecido-específico.
Exercise training (T) does not reduce pressure in normotensive, but causes peripheral and central adjustments on cardiovascular system, mediated by autonomic nervous system. In this study we investigated whether T (55% maximal exercise capacity) is able to change vascular sympathetic drive to skeletal muscle (locomotor, non-locomotor), kidney and adrenals, using immunohistochemistry and western blot for tyrosine hydroxylase (TH). T improved performance (+0,07±0,06 Km/h) and reduced resting HR (from 327±7 to 308±10 bpm) without changing MAP (126mmHg) and arterioles wall/ lumen ratio in any tissue. T caused 48% decrease on TH-immunoreactivity of exercised muscles arterioles, without changes on non-exercised tissues. Norepinephrine concentration on femoral arteries was reduced after T. There was no change on adrenal. TH content. Decreased sympathetic drive to skeletal muscles arterioles (without changes on plasma cathecolamines) is a beneficial, tissue-specific effect in normotensive individuals.
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Carvalho, Carolina da Silva. "Identificação dos neurotransmissores das fibras mielínicas e amielínicas do nervo depressor aórtico de ratos: uma abordagem imunohistoquímica." Universidade de São Paulo, 2016. http://www.teses.usp.br/teses/disponiveis/17/17140/tde-06012017-115951/.

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O nervo depressor aórtico (NDA) é, primariamente, um conjunto de fibras aferentes que transmitem informações oriundas de alterações da pressão arterial (PA) a partir dos barorreceptores arteriais (mecanorreceptores localizados no arco da aorta ou seio carótico) aos centros de controle cardiovascular localizados no sistema nervoso central (SNC). Este mecanismo é responsável pela regulação reflexa da função cardíaca e vascular, promovendo ajustes nos centros vasoconstritor e vasodilatador, atuando simultaneamente sobre os sistemas simpático e parassimpático. Fato este que, contribui para o aumento da atividade vagal cardíaca e inibição de descargas simpáticas para vasos e coração, garantindo a manutenção dos níveis pressóricos dentro de uma faixa de normalidade. Diversos neurotransmissores foram descritos atuando nos centros de controle cardiocirculatório localizados no tronco encefálico, mais especificamente no bulbo, participando da regulação da PA. Nestas regiões centrais, os neurotransmissores glutamato, GABA (Àcido Gama Aminobutírico) e substância P (SP) foram amplamente investigados. Entretanto, em nenhum destes trabalhos foi realizado um estudo detalhado, investigando a presença da SP em nervos depressores aórticos de forma direta, sendo esta informação ainda desconhecida. Acredita-se que a SP seja um transmissor do reflexo barorreceptor, atuando na modulação deste circuito, na tentativa de atenuar elevações da pressão sanguínea. Existe portanto a necessidade de uma investigação morfológica e imunohistoquímica com o intuito de promover o esclarecimento sobre os neurotransmissores presentes no NDA. Os nervos frênicos foram utilizados como controle positivo, já que neste território a SP já se encontra caracterizada. Inúmeros são os estudos que descrevem a existência da SP em nervos frênicos, fato este que justifica a aplicação do referido nervo como controle do NDA, foco de estudo deste projeto. Baseados nestas necessidades, o objetivo do presente estudo foi primeiramente o de promover a padronização da técnica imunohistoquímica (IHQ), bem como a verificação da viabilidade de utilização do glutaraldeído à 2,5% como um fixativo primário, auxiliando na identificação de neurotransmissores dentro do sistema nervoso periférico. Em seguida, a identificação e quantificação da SP em NDA de ratos normotensos através do método imunohistoquímico indireto (3,3\'- Diaminobenzidina \"DAB\") foram realizados. O referido estudo foi desenvolvido em duas etapas. A primeira parte corresponde a padronização e otimização da técnica de imunohistoquímica em nervos frênicos de ratos Wistar através da localização e caracterização da SP e da enzima colina acetiltransferase (CAT). A segunda fase, trata-se da identificação e quantificação da SP no NDA, sendo este, um possível neurotransmissor ou neuromodulador do reflexo barorreceptor. Para este estudo foram utilizados no total 38 ratos da linhagem Wistar (Rattus Norvegicus), normotensos, com 20 semanas de idade, machos e fêmeas. Deste total, 16 animais machos foram destinados à padronização da técnica de IHQ em nervos frênicos. E para a caracterização e quantificação da SP no NDA foram utilizados 22 ratos Wistar, sendo 12 machos e 10 fêmeas. Nossos resultados demonstram de forma inédita a presença da SP em fibras amielínicas (tipo C) e fibras de pequeno diâmetro (A-delta) no NDA de forma bastante pontualizada em segmentos proximais e difusa distalmente, sugerindo a existência de subpopulações de fibras amielínicas do tipo C. Estes achados confirmam inúmeras suposições de que a SP atue como um dos neurotransmissores de aferências barorreceptoras, podendo participar na modulação do Sistema Nervoso Autônomo (SNA), uma vez que encontra-se localizada em centros responsáveis pela regulação reflexa da PA. Adicionalmente, a análise do percentual de marcação positiva à SP entre os gêneros apresentou um aparente predomínio da SP em machos mas sem diferença significativa entre os grupos. De forma semelhante, a padronização imunohistoquímica em cortes transversais e longitudinais de nervos frênicos apresentaram uma imunomarcação positiva e aleatória da SP em conjuntos de fibras amielínicas (tipo C) e em fibras de pequeno diâmetro localizadas próximo a periferia do espaço endoneural, corroborando com a localização relatada em estudos morfológicos e ultraestruturais, assegurando a especificidade e a reprodutibilidade do método. Distintamente, as fibras de grande e médio diâmetro (A-alfa, beta e gama), consideradas fibras mielinizadas de condução rápida, foram imunorreativas à CAT em nervos frênicos. Por fim, espera-se que a identificação deste neuropeptídeo sirva de gatilho para que futuras pesquisas envolvendo a liberação de neurotransmissores em aferências barorreceptoras sejam explorados. Fato este, que contribuirá para a agregação de informações pertinentes à modulação ou transmissão da informação neural, propiciando desta forma melhor entendimento da comunicação e atividades barorreflexas associadas a mecanismos cardiovasculares.
The aortic depressor nerve (ADN) is primarily a set of afferent fibers that transmit derived information of changes in arterial blood pressure (BP) from arterial baroreceptors (mechanoreceptors located in the aortic arch and carotid sinus) to sites of cardiovascular control located into central nervous system (CNS). This mechanism is responsible for the reflex regulation of cardiac and vascular function, promoting adjustments of vasoconstrictor and vasodilator centers, simultaneously acting on the sympathetic and parasympathetic systems. In addition, contributes to increased cardiac vagal activity and inhibition of sympathetic discharges to vessels and heart, ensuring the maintenance of blood pressure levels within the normal range. Many neurotransmitters have been described operating in cardio-circulatory control centers located in the brainstem, more specifically in the bulb, participating in the regulation of BP. In these central regions, the neurotransmitters glutamate, GABA (Gamma Aminobutyric Acid) and substance P (SP) have been widely investigated. However, none of these works was carried out a detailed study, investigating the presence of SP in aortic depressor nerves directly, and this information is still unknown. It is believed that SP can be a transmitter at the synapse of the baroreceptor reflex, operating in the modulation of this circuit in an attempt to attenuate elevation of blood pressure. Therefore, there is a need to investigate a morphological and immunohistochemical approach in order to promote the clarification on the present neurotransmitters into ADN. The phrenic nerves were used as a positive control, already as substance P (SP) is characterized in this territory. There have been numerous studies describing the existence of SP in phrenic nerves, a fact that justifies the application of the nerve as control of the ADN, study focus of this project. Based on these requirements, the aim of the present study is two-fold. Firstly, it attempts to promote the standardization of the immunohistochemical (IHC) technique as well as the verification of the feasibility of using glutaraldehyde fixative as a primary, assisting in the identification of neurotransmitters in the peripheral nervous system (PNS). Subsequently, the identification and quantification of SP immunoreactivity in the ADN of normotensive rats by indirect immunohistochemical method (3,3\'-Diaminobenzidine \"DAB\") were done. The study was developed in two stages. The first part corresponds to standardization and optimization of immunohistochemical technique in phrenic nerves of Wistar rats through location and characterization of the SP and enzyme choline acetyltransferase (ChAT). The second phase is about the identification and quantification of the SP into ADN, being a possible neurotransmitter or neuromodulator from the baroreceptor reflex. For this study we used a total of 38 Wistar rats (Rattus norvegicus), normotensive, 20 weeks old, male and female. From this total, 16 male animals were used for standardization of IHC technique in the phrenic nerves. Nonetheless, for the characterization and quantification of SP in ADN were used 22 Wistar rats, 12 males and 10 females. Our results showed an unprecedented manner the presence of SP in unmyelinated fibers (type C) and small diameter fibers (A-delta) into ADN, being quite focused on proximal segments and diffuse distally, suggesting the existence of subsets of unmyelinated fibers. These findings confirm numerous assumptions that the SP acts as a neurotransmitter from afferent baroreceptor and may participate in the modulation of the Autonomic Nervous System (ANS), since it is located in centers responsible for regulating reflex of BP. Further, an analysis of the percentage of positive SP staining between genders, presented an apparent predominance of SP in males but no significant difference between the groups were found. Similarly, IHC standardization in transverse and longitudinal sections of phrenic nerves showed a positive random and immunostaining of SP in sets of unmyelinated fibers (type C) and small diameter fibers located near the periphery of endoneural space, corroborating location reported on morphological and ultrastructural studies, ensuring the specificity and reproducibility of the method. Distinctly, the fibers of large and medium diameters (A-alpha, beta and gamma), considered myelinated fibers of fast conducting, were immunoreactive to ChAT in phrenic nerves. Finally, it is expected that the identification of neuropeptide serve as a trigger for that future studies involving the release of neurotransmitters into afferent baroreceptors be explored. These results could contribute to the aggregation of relevant information for the modulation and transmission of neural information, thus providing better understanding of communication and baroreflex activities associated with cardiovascular mechanisms.
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Arantes, Ana Carolina. "Efeitos da redução da ingestão de sal sobre a pressão arterial em normotensos, pré-hipertensos e normotensos." Universidade Federal de Goiás, 2017. http://repositorio.bc.ufg.br/tede/handle/tede/7904.

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Introduction: The effects of salt intake reduction on casual blood pressure (BP) among hypertensive patients have been widely studied. However, there are few data about this issue in the context of arterial stiffness, as well as in normotensive and pre-hypertensive subjects. Objective:To evaluate the effects of progressive reduction in intake of the addition salt (from 6 grams / day to 4 grams/day) on peripheral and central pressure values as well as arterial stiffness in normotensive, prehypertensive and hypertensive. Methodology: This is an interventional, single-blind clinical trial, with 13 weeks of follow-up and 4 weeks interval between evaluations, performed with technical-administrative workers and teachers from a public university. Inclusion criteria were age between 20 and 60 years, both genders and which meal at home at least 4 times per week. Exclusion criteria were BP ≥160/100 mmHg, using two or more antihypertensive drugs, secondary hypertension; diabetes, history of myocardial infarction or stroke in the last 6 months, and special need diet. This study was approved by the institution’s Ethics Committee and all the participants signed the informed consent form. Recruitment was performed at the workplace, with a questionnaire about dietary habits, anthropometric and casual BP measurement (OMRON 705CP automatic device). According to the BP levels, participants were classified as normotensive (≤130/85 mmHg), pre-hypertensive (130-139/85-89 mmHg) and hypertensive stage I (≥140- 159/90-99 mmHg). The other evaluated variables were home blood pressure monitoring (HBPM), central blood pressure (CBP) measurement by tonometry (SphygmoCor® system), 24-hour urinarysodium, and dietary salt intake. The participants were instructed to reduce the consumption of foods with high sodium content. The addition of salt used during the follow-up was controlled by delivering individual packages for daily family consumption. The protocol adherence was evaluated by controlling the returned packages at each visit. The data were structured and analyzed using Stata software (version 12). Descriptive analysis was performed using relative and absolute frequencies, as well as median and interquartile range or mean and standard deviation for distribution of categorical and quantitative variables, respectively. For comparison between groups at visit 1, Kruskal-Wallis and Fisher's Exact tests were used. The comparison between the groups was done before and after the intervention using Wilcoxon test and paired Student T test. The correlation between BP values and urinary sodium levels was performed using the Spearman test. For all tests, the significance level was set at 5% and the confidence interval was 95%. Results: Fifty-five participants were evaluated, 32 males (median age 48 years). According to BP values, 18 were normotensive, 15 pre-hypertensive and 22 hypertensive. The salt of addition was reduced at each visit from 6 to 4 g/day. The groups are similar in relation to age and sex. There was no difference between blood pressure measurements and sodium excretion before and after the intervention. The parameters of arterial stiffness also did not suffer. Conclusion: Gradual reduction of addition salt intake in a 13-week follow-up is not able to reduce the loss of danger and mean values of blood pressure.
Introdução: Os efeitos da redução na ingestão de sal sobre a pressão arterial casual de hipertensos já foram amplamente estudados, entretanto essa análise ainda é escassa no contexto da rigidez arterial e em indivíduos normotensos e pré-hipertensos. Objetivo: Avaliar os efeitos da redução progressiva na ingestão do sal de adição (de 6 gramas/dia para 4 gramas/dia) sobre os valores dapressão periférica e central assim como a rigidez arterial em normotensos, pré-hipertensos e hipertensos. Metodologia: Ensaio clínico, simples cego, com 13 semanas de seguimento e intervalo de 4 semanas entre as consultas, realizado com trabalhadores técnico-administrativos e docentes universitários. Critérios de inclusão: idade entre 20 a 60 anos, para ambos os sexos e refeição principal (almoço e/ou jantar) em casa no mínimo 4x/semana. Critérios de exclusão: pressão arterial (PA) ≥160/100 mmHg, uso de dois ou mais medicamentos anti-hipertensivos, hipertensão secundária; diabéticos, história de infarto do miocárdio ou acidente vascular cerebral nos últimos 6 meses e necessidade de alguma dieta especial. Este estudo foi aprovado pelo Comitê de Ética em Pesquisa da instituição e os participantes assinaram o Termo de Consentimento Livre e Esclarecido. O recrutamento foi realizado no local de trabalho, aplicando-se questionários sobre hábitos alimentares, medidas antropométricas e medida casual da PA com o aparelho automático OMRON 705CP. Os participantes foram classificados, de acordo com a medida casual da pressão arterial, em normotensos (≤130/85 mmHg), pré-hipertensos (130-139/85-89 mmHg) e hipertensos estágio I (≥140-159/90-99 mmHg). As variáveis avaliadas foram a medida casual, monitorização residencial da pressão arterial (MRPA), medida central da pressão arterial (PAC) por tonometria com o aparelho sphygmocor, sódio urinário de 24h e mensuração do sal de adição. Os participantes foram orientados a reduzir o consumo de alimentos com alto teor de sódio e o sal de adição utilizado no período do seguimento foi controlado com a entrega em embalagens individuais, para o consumo diário familiar. A adesão ao protocolo foi avaliada pelo controle das embalagens e pesagem do sal de adição retornado em cada visita. Os dados foram estruturados e analisados no programa Stata versão 12. Foram utilizadas frequências absolutas e relativas para análise estatística descritiva e mediana e intervalo inter-quartil ou média e desvio padrão, para as variáveis categóricas e quantitivas. A distribuição dos dados foi analisada pelo teste Shapiro-Wilk; para a comparação entre grupos na V1B foram realizados os testes de Kruskal-Wallis e Exato de Fisher; comparação intra grupo foi feita antes e após a intervenção pelos testes de Wilcoxon e t-Student pareado; correlação entre valores de PA e níveis de sódio urinário via teste de Spearman. Para todos os testes considerou-se o nível de significância em 5% e intervalo de confiança de 95%. Resultados: Foram avaliados 55 participantes com intervalos de 04 semanas, 32 do sexo masculino (mediana de 48 anos) sendo 18 normotensos, 15 pré-hipertensos e 22 hipertensos, redução progressiva no sal de adição a cada visita de 6 até 4 gramas ao dia. Os grupos foram semelhantes em relação a idade e sexo. Não houve diferença entre medidas de pressão arterial e excreção de sódio antes e depois da intervenção. Os parâmetros de rigidez arterial também não sofreram alterações significativas. Conclusão: A redução gradativa da ingestão de sal de adição num seguimento de 13 semanas não foi capaz de reduzir de maneira significativa os valores periféricos e centrais da pressão arterial.
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Bloos, Frank. "Coronary circulatory reserve in normotensive hyperdynamic sepsis." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape7/PQDD_0011/NQ40242.pdf.

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Matoso, Juliana Magalhães Duarte. "Desempenho cognitivo em idosos hipertensos e normotensos." Universidade do Estado do Rio de Janeiro, 2012. http://www.bdtd.uerj.br/tde_busca/arquivo.php?codArquivo=6174.

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Conselho Nacional de Desenvolvimento Científico e Tecnológico
A população de idosos cresce rapidamente no Brasil. A prevalência de hipertensão arterial sistêmica (HAS) e distúrbios cognitivos é elevada nesta população. Testamos a hipótese de que a HAS reduz o desempenho cognitivos em idosos. Foram selecionamos idosos hipertensos e normotensos com idade ≥ 60 < 80. O desempenho cognitivo foi avaliado pelo Cambridge Cognitive Examination Revised (CAMCOG-R), por subtestes do Wechsler Adult Intelligence Scale v.3 (WAIS III), além do Rey Auditory Verbal Learning Test (RAVLT), e o dos Trail Making Tests A/B (TMT-A/B). O desempenho cognitivo avaliado pelo escore global do CAMCOG-R e do QI estimado do WAIS III está reduzido nos idosos hipertensos mesmo quando controlado pela escolaridade, depressão, estado geral de saúde e qualidade de vida. O desempenho cognitivo em diversos domínios específicos controlados para a escolaridade, depressão, estado geral de saúde e qualidade de vida, e avaliados pelo CAMCOG-R, WAIS III, TMT-A e RAVLT também está reduzido nos idosos hipertensos. O presente estudo sugere que a HAS está associada ao declínio do desempenho cognitivo global em idosos. Notadamente, o desempenho das funções executivas está reduzido nos idosos hipertensos. Especula-se que a HAS seja um fator de risco para o declínio progressivo do desempenho cognitivo e, portanto, para o desenvolvimento de demência.
The elderly population is growing rapidly in Brazil. The prevalence of hypertension and cognitive disorders is high in this population. We tested the hypothesis that hypertension is associated with decreased cognitive performance in the elderly. We selected normotensive and hypertensive subjects aged ≥ 60 <80 years old. Cognition was assessed through Cambridge Cognitive Examination Revised (CAMCOG-R), subtests of the Wechsler Adult Intelligence Scale v.3 (WAIS III), the Rey Auditory Verbal Learning Test (RAVLT), and the Trail Making Tests A/B (TMT-A/B). The cognitive performance assessed by the CAMCOG-R global score and the estimated WAIS III. QI is reduced in elderly hypertensives even when controlled for education, depression, health status and quality of life. The cognitive performance in diverse cognitive domains assessed through CAMCOG-R, WAIS III, TMT-A e RAVLT is also reduced in elderly hypertensives when contolled for education, depression, health status and quality of life. These results suggest that hypertension is associated with reduced global cognitive performance in eldely hypertensives. Notably, executive functions are reduced in eldely hypertensives. We speculate that hypertension might be a risk factor for the progressive decline in cognitive function and, therefore, for the development of dementia.
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Klein, Maria. "Stressreagibilität bei jungen salzsensitiven und salzresistenten normotensiven Frauen /." Berlin, 2008. http://opac.nebis.ch/cgi-bin/showAbstract.pl?sys=000253703.

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Morgan, Jennifer A. "Leucocyte sodium transport in normotensive and hypertensive pregnancy." Thesis, University of Leeds, 1988. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.236321.

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Books on the topic "Normotension"

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Akpogomeh, Benjamin Agbayemie. A Study of alpha-adrenoceptors involved in the neural control of sodium reabsorption by the kidney in normotension, genetic and two models of experimental hypertension. University of Birmingham, 1989.

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Davis, Gerard. Reflex neural regulation of renal function in normotensive and hypertensive rats. University of Birmingham, 1991.

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Laine, Krista. Intraocular pressure lowering activities of endogenous cannabinoids, and their uptake and enzyme hydrolysis inhibitors in normotensive rabbits. University of Kuopio, 2004.

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Yang, Zhuo. The influence of the paraventricular nucleus of the hypothalamus on cardiovascular neurones in the ventrolateral medulla in normotensive and hypertensive rats. University of Birmingham, 1999.

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Jacoby, Anne Catherine. CARDIOVASCULAR CIRCADIAN RHYTHMS IN NORMOTENSIVE AND HYPERTENSIVE ADOLESCENTS. 1988.

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Banasik, Jacquelyn Lou. Endothelin binding in brain of normotensive and spontaneously hypertensive rats. 1991.

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Broege, Phyllis Anne. THE BLOOD PRESSURE RESPONSE TO DAILY STRESS IN NORMOTENSIVE FEMALE NURSES. 1994.

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Moore, R. Leigh Hill. Hypotensive effect of isometric exercise on resting blood pressure in high normotensive subjects. 1986.

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Kelly, Frecia Marie. THE EFFECTS OF ANGER UPON BLOOD PRESSURE REACTIVITY IN NORMOTENSIVE AND HYPERTENSIVE SUBJECTS. 1986.

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Terapia manual del sistema miofascial : la terapia normotensiva aplicada a las disfunciones del sistema musculoesqueletico. Masson, 2002.

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Book chapters on the topic "Normotension"

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Suzuki, Takahiro, Kyuzo Aoki, and Koichi Miyagawa. "Pressor Effects of Calcium Infusion in the Absence and Presence of a Calcium Antagonist in Subjects with Normotension and Hypertension." In Essential Hypertension 2. Springer Japan, 1989. http://dx.doi.org/10.1007/978-4-431-68090-1_24.

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Rost, R., H. Heck, and K. Völker. "Ergometrisches Follow-up des Blutdruckverhaltens bei normotensiven Erwachsenen." In Belastungsblutdruck bei Hochdruckkranken. Springer Berlin Heidelberg, 1993. http://dx.doi.org/10.1007/978-3-642-77975-6_11.

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Naranjo, C. A., K. E. Bremner, P. Sanhueza, and E. M. Sellers. "Enalapril Does not Decrease Alcohol Intake in Normotensive Alcoholics." In Novel Pharmacological Interventions for Alcoholism. Springer New York, 1992. http://dx.doi.org/10.1007/978-1-4612-2878-3_17.

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Pittman, Quentin J. "Brain Vasopressin and Cardiovascular Regulation in Normotensive and Hypertensive Animals." In Neuropeptides and Stress. Springer New York, 1989. http://dx.doi.org/10.1007/978-1-4612-3514-9_11.

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Prager, G., R. Prager, and P. Klein. "Age-Dependent Variation of Diurnal Blood Pressure Profile in Normotensive Subjects." In Temporal Variations of the Cardiovascular System. Springer Berlin Heidelberg, 1992. http://dx.doi.org/10.1007/978-3-662-02748-6_25.

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McCarron, R. M., Y. Yoshihide, M. Spatz, and J. Hallenbeck. "Hypertensive Versus Normotensive Monocyte Adhesion to Cultured Cerebral Microvascular Endothelial Cells." In Biology and Physiology of the Blood-Brain Barrier. Springer US, 1996. http://dx.doi.org/10.1007/978-1-4757-9489-2_48.

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Earle, M. L., T. Horn, N. Kasting, R. Landgraf, and Q. J. Pittman. "Ventral Septal AVP Release in the Febrile Hypertensive and Normotensive Rat." In Thermal Balance in Health and Disease. Birkhäuser Basel, 1994. http://dx.doi.org/10.1007/978-3-0348-7429-8_54.

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Rossi, Gian Paolo, Teresa Maria Seccia, and Paola Caielli. "Primary Aldosteronism: Rare or Common Condition in Hypertensive Patients and Normotensive Individuals?" In Special Issues in Hypertension. Springer Milan, 2012. http://dx.doi.org/10.1007/978-88-470-2601-8_4.

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Podos, S. M., C. B. Camras, J. B. Serle, and P. Y. Lee. "Pharmacologic Alteration of Aqueous Humor Dynamics in Normotensive and Glaucomatous Monkey Eyes." In Glaucoma Update III. Springer Berlin Heidelberg, 1987. http://dx.doi.org/10.1007/978-3-642-71785-7_33.

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Wang, Duo H., and Russell L. Prewitt. "Reduced Aortic and Arteriolar Growth by Captopril in Normotensive and Renal Hypertensive Rats." In Advances in Experimental Medicine and Biology. Springer US, 1991. http://dx.doi.org/10.1007/978-1-4684-6015-5_19.

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Conference papers on the topic "Normotension"

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Lande, K., I. O. S. S. E. Kieldsen, A. Westheim, et al. "PATIENTS WITH MILD ESSENTIAL HYPERTENSION HAVE INCREASED PLATELET SIZE AND RELEASE REACTION ANO SHOW INCREASED RECEPTOR RESPONSE TO INFUSED ADRENALINE." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644261.

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Hypertensive (n = 35) and normotensive {n = 44) men all 42 years old were studied. The hypertensive (HT) had larger venous platelets than the normotensive (HT) (7.46 ± 0.10 vs 7.12 ± 0.09 10-15 1, p = 0.01). Plasma concentration of |3-thromboglobulin (BTG) was increased in arterial blood in hypertensive (40 ± 8 vs 21 ± 2 ug/1, p=0.02) while the venous values were similar in the two groups. Despite similar sampling procedure, the normotensive subjects had markedly higher BTGconcentration in venous compared to arterial blood (p≺0.01) at variance from thehypertensive where the arteriovenous difference in plasma BTG concentration was not present. Adrenaline was infused to 13 hypertensive and 12 normotensive subjects with dose gradually increasing to 0.04 pg/kg/min. Forearm blood flow was measured by strain gauge technique and relative forearm resistance calculated as mean blood pressure divided by flow. Twelve normotensive subjects (control group) received saline infusion.Change in forearm resistance reflectsβ2- activation of smooth vascular cells, change in platelet count reflects splenic liberation of platelets in response to adrenergic stimulation while change in BTG may reflect platelet release upon stimulation of α2 -receptors. Thus, middle aged men with essential hypertension show increased sensitivity to adrenaline infusion in vascular smooth muscle, spleen and platelets.
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Solverson, Kevin, Christopher Humphreys, Zhiying Liang, et al. "Refining risk in normotensive acute pulmonary embolism." In ERS International Congress 2019 abstracts. European Respiratory Society, 2019. http://dx.doi.org/10.1183/13993003.congress-2019.pa3646.

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Boekhoven, R. W., L. Marais, M. C. M. Rutten, F. N. vd Vosse, P. Boutouyrie, and R. G. P. Lopata. "Non-invasive strain imaging in normotensive and hypertensive patients." In 2014 IEEE International Ultrasonics Symposium (IUS). IEEE, 2014. http://dx.doi.org/10.1109/ultsym.2014.0448.

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Tsamis, Alkiviadis, Nikos Stergiopulos, and Alexander Rachev. "A Structure-Based Model of Arterial Remodeling in Response to Sustained Hypertension." In ASME 2009 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2009. http://dx.doi.org/10.1115/sbc2009-206338.

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Pressure-induced remodeling of arteries is an adaptive process, which restores the magnitude of media tensile stress and intimal shear stress to their baseline values under normotensive conditions [1]. Revealing the role that mechanical factors play in arterial adaptation is important for understanding the normal arterial function as well as the pathogenesis of various arterial diseases.
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Bodzenta-Lukaszvk, A., K. Krupiński, and M. Bielawiec. "PLATELET FUNCTION AND KALLIKREIN SYSTEM IN PATIENTS WITH ESSENTIAL HYPERTENSION." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644258.

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Since the pathogenesis of hypertension is still discussed the aim of this study was to investigate behaviour of platelets and kallikrein system in patients suffering from this disease. In 30 patients with essential hypertension, aged 23-31 years and 20 normotensive healthy subjects, aged 21-35 years the following parameters of platelet function were studied: platelet aggregation induced with ADP,platelet activating factor (PAF) and arachidonic acid (AA) according Born's method, plasma beta-thromboglobulin (Beta-TG) and platelet factor 4 (PF4) , plasma thromboxane B2 (TXB2) and cyclic AMP using radioimmunoassay kits. The activity of kallikrein and factor XII was also determined using Chromo-zym PK (Boehringer Mannheim GmbH). The hypertensive patients demonstrated a greater platelet aggregability by ADP and PAF, elevated concentrations of Beta-TG and TXB2 as well as decreased level of cyclic AMP in comparison to normotensive subjects. No significantly changes in platelet aggregability by AA and activity of PF4 were found in the group of hypertensive patients. There were also significantly decreased plasma concentrations of kallikrein and factor XII in these patients. Obtained results have shown hyperfunction of blood platelets and depletion of kallikrein system in the patients with essential hypertension. These results suggest that among different pathogenic factors function of blood platelets and kallikrein system should be taken into consideration.
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Xi, Shou-min, San-qiang Li, and Wei-dong Yin. "Topical Application of Melatonin Analogue Neu-P11 Reduces Intraocular Pressure in Normotensive Rabbit." In 2012 International Conference on Biomedical Engineering and Biotechnology (iCBEB). IEEE, 2012. http://dx.doi.org/10.1109/icbeb.2012.451.

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Ali, S., L. Alnimer, H. A. Rauf, and J. R. Heffernan. "PRES in a Normotensive Patient with Sickle Cell Disease: Low Pressure, Alarming Consequences." In American Thoracic Society 2020 International Conference, May 15-20, 2020 - Philadelphia, PA. American Thoracic Society, 2020. http://dx.doi.org/10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a7211.

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Silveri, Giulia, Lorenzo Pascazio, and Agostino Accardo. "Relationship Between Blood Pressure and Heart Rate Circadian Rhythms in Normotensive and Hypertensive Subjects." In 2018 Computing in Cardiology Conference. Computing in Cardiology, 2018. http://dx.doi.org/10.22489/cinc.2018.273.

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Al-Jahawsheh, Shibley, Basheer Na'amneh, Duha Al-Batayha, and Mohammad Al-Abed. "Analysis of Corrected QT Interval Dispersion (QTcd) in Normotensive Subjects Performing Breath-hold Challenge." In 2020 IEEE 5th Middle East and Africa Conference on Biomedical Engineering (MECBME). IEEE, 2020. http://dx.doi.org/10.1109/mecbme47393.2020.9265167.

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10

Kouchaki, Zahra, Mark Butlin, and Alberto P. Avolio. "Hemodynamics changes with acute carotid baroreceptor field stimulation are age-dependent in normotensive rats*." In 2015 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC). IEEE, 2015. http://dx.doi.org/10.1109/embc.2015.7318790.

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Reports on the topic "Normotension"

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Kramer, George C. Closed-Loop Resuscitation of Hemorrhagic Shock: Novel Solutions Infused to Hypotensive and Normotensive Endpoints. Defense Technical Information Center, 2007. http://dx.doi.org/10.21236/ada470719.

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