Relevant bibliographies by topics / Novel Bile Acid Conjugates

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  1. Journal articles
  2. Dissertations / Theses
  3. Book chapters
  4. Conference papers
  5. Reports

Academic literature on the topic 'Novel Bile Acid Conjugates'

Author: Grafiati
Published: 4 June 2021
Last updated: 6 September 2023

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Journal articles on the topic "Novel Bile Acid Conjugates"

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Mishra, Satyendra, and Sejal Patel. "Design, Synthesis, and Anti-bacterial Activity of Novel Deoxycholic Acid- Amino Alcohol Conjugates." Medicinal Chemistry 16, no. 3 (2020): 385–91. http://dx.doi.org/10.2174/1573406415666190206231002.

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Background: Numerous synthetic bile acid derivatives have been recognized for their various biological activities. Among these, bile acid amides have emerged as an attractive antibacterial agent. We herein illustrate the synthesis and antibacterial evaluation of deoxycholic acidamino alcohols conjugates. Objective: Design and Synthesis of novel deoxycholic acid-amino alcohol conjugates to investigate their antibacterial activity against E. coli and S. aureus. Methods: Novel deoxycholic acid-amino alcohol conjugates were synthesized, from conjugation of deoxycholic acid-NHS ester with amino alc
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Ahonen, Kari V., Manu K. Lahtinen, Miika S. Löfman, et al. "Structural studies of five novel bile acid-4-aminopyridine conjugates." Steroids 77, no. 11 (2012): 1141–51. http://dx.doi.org/10.1016/j.steroids.2012.06.003.

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Chong, Hyun-Soon, Yunwei Chen, Chi Soo Kang, Xiang Sun, and Ningjie Wu. "Novel 64Cu-radiolabeled bile acid conjugates for targeted PET imaging." Bioorganic & Medicinal Chemistry Letters 25, no. 5 (2015): 1082–85. http://dx.doi.org/10.1016/j.bmcl.2015.01.008.

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Li, Yan, Weijun Chu, and Yong Ju. "Novel bile acid derivedH-phosphonate conjugates: Synthesis and spectroscopic characterization." Heteroatom Chemistry 19, no. 4 (2008): 402–7. http://dx.doi.org/10.1002/hc.20447.

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Jin, Xue-Yuan, Chuan-Bao Zhu, Shi-Yong Fan, et al. "Novel hypolipidemic conjugates of fatty acid and bile acid with lysine for linkage." Drug Development and Industrial Pharmacy 45, no. 6 (2019): 995–98. http://dx.doi.org/10.1080/03639045.2019.1590393.

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Koivukorpi, Juha, and Erkki Kolehmainen. "Novel bile acid conjugates with aryl/alkenyl linker: Synthesis and characterization." Journal of Molecular Structure 889, no. 1-3 (2008): 211–16. http://dx.doi.org/10.1016/j.molstruc.2008.01.050.

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Noponen, Virpi, Shreedhar Bhat, Elina Sievänen, and Erkki Kolehmainen. "Novel two-step synthesis of gold nanoparticles capped with bile acid conjugates." Materials Science and Engineering: C 28, no. 7 (2008): 1144–48. http://dx.doi.org/10.1016/j.msec.2007.10.001.

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Blagbrough, I. S., A. J. Geall, and A. P. Neal. "Polyamines and novel polyamine conjugates interact with DNA in ways that can be exploited in non-viral gene therapy." Biochemical Society Transactions 31, no. 2 (2003): 397–406. http://dx.doi.org/10.1042/bst0310397.

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As a part of our continuing studies on ‘Polyamines and their role in human disease’ we are investigating how polyamines, and especially how novel polyamine conjugates, interact with DNA. We are studying how these conjugates interact with circular plasmids in order to produce nanometre-sized particles suitable for transfecting cells. Our considerations of structure--activity relationships (SAR) within naturally occurring and synthetic polyamines have shown the significance of the inter-atomic distances between the basic nitrogen atoms. As these atoms are typically fully protonated under physiol
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Yang, Min, Yu Gu, Lingfeng Li, et al. "Bile Acid–Gut Microbiota Axis in Inflammatory Bowel Disease: From Bench to Bedside." Nutrients 13, no. 9 (2021): 3143. http://dx.doi.org/10.3390/nu13093143.

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Inflammatory bowel disease (IBD) is a chronic, relapsing inflammatory disorder of the gastrointestinal tract, with increasing prevalence, and its pathogenesis remains unclear. Accumulating evidence suggested that gut microbiota and bile acids play pivotal roles in intestinal homeostasis and inflammation. Patients with IBD exhibit decreased microbial diversity and abnormal microbial composition marked by the depletion of phylum Firmicutes (including bacteria involved in bile acid metabolism) and the enrichment of phylum Proteobacteria. Dysbiosis leads to blocked bile acid transformation. Thus,
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Thorpe, Cheleste M., Xi Qian, Karin Yanagi, et al. "2567. Effect of Broad vs. Narrow-Spectrum Clostridioides difficile Treatment on Human Stool Bile Acid Composition Over Time." Open Forum Infectious Diseases 6, Supplement_2 (2019): S891. http://dx.doi.org/10.1093/ofid/ofz360.2245.

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Abstract Background Secondary bile acid production by a diverse commensal flora may be a critical factor in preventing recurrence of Clostridioides difficile infection (CDI). Key enzymes involved are bacterial-encoded bile salt hydrolases (BSHs), felt to be “gatekeepers” to secondary bile acid synthesis. Ridinilazole, a novel narrow-spectrum drug for CDI, demonstrated superior sustained clinical response compared with vancomycin in Phase 2. Longitudinal sampling during this trial allowed for assessment of metabolites differentially present in stools during/after therapy with either broad or na
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Dissertations / Theses on the topic "Novel Bile Acid Conjugates"

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CHINAGLIA, Nicola. "Design, synthesis and biological evaluation of novel nucleoside and oligonucleotide conjugates of bio-medical interest." Doctoral thesis, Università degli studi di Ferrara, 2019. http://hdl.handle.net/11392/2487947.

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Bioconjugation is the process of linking or connecting a biological molecule with another moiety. This moiety may include another biomolecule: in this case a hybrid is formed, in which the properties of the parent molecules are integrated, yielding a single entity with two different functions. With the aim to discover new nucleoside-based compounds of bio-medical interest, we consider bioconjugation as a powerful approach. In light of the well-known therapeutic potential of nucleosides as antitumorals and antivirals, in the first work reported in this thesis a conjugate between 2'-deoxyadenosi
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Trusova, Tatyana. "Quantitative estimation of bile acid conjugates in human bile using HPLC /." Connect to online version, 1995. http://hdl.handle.net/1989/3555.

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Hurley, J. P. "Novel bile acid-hydrogel systems as potential nedical device biomaterials." Thesis, Queen's University Belfast, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.269055.

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Tierney, Juliann Jude. "The synthesis and testing of novel cholic acid based stationary phases." Thesis, University of Bristol, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.247854.

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Bhattacharya, Shiladitya. "Novel folate amphiphile conjugates for targeted drug delivery." Scholarly Commons, 2008. https://scholarlycommons.pacific.edu/uop_etds/2360.

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Cancer is not only difficult to treat but the patients also suffer from the pain associated with anticancer treatments. Targeted chemotherapeutics can reduce the adverse effects by reducing the dose required for tumor cell kill. Cancers of various origins often have characteristic marker molecules that distinguish them from the normal tissues. Folate receptors are such marker molecules present in ovarian and cervical cancers. The hypothesis for the current study is that amphiphiles constructed out of folic acid, the natural ligand for the folate receptor, can deliver paclitaxel, a chemotherape
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Duncan, Kenneth William. "Development of a synthetic methodology towards novel bile acid and cholesterol analogues." Thesis, University of Strathclyde, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.248838.

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Gopaul, Vedwatee Sashi. "The identification, characterization and profiling of novel thiol and amino acid conjugates of valproic acid in humans and animals." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1998. http://www.collectionscanada.ca/obj/s4/f2/dsk2/tape17/PQDD_0007/NQ34524.pdf.

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Trujillo, Jesse, та Jesse Trujillo. "A Novel Mechanism for Bile Acid Induced Activation of Estrogen Receptor β in Colorectal Cancer". Diss., The University of Arizona, 2016. http://hdl.handle.net/10150/622961.

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Primary bile acids are a group of cholesterol metabolites that are synthesized in the liver and stored in the gallbladder. The main role of bile acids is to aid in the digestion of dietary fats and lipids. More recently, a signaling role for bile acids has been characterized. Secondary bile acids are formed when the bacteria of the colon metabolize primary bile acids. Secondary bile acids that escape enterohepatic re-uptake to the liver can have a deleterious effect in the colon. Deoxycholic acid (DCA) and ursodeoxycholic acid (UDCA) are two secondary bile acids that have been studied for thei
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Almarghalani, Daniyah Abduljalil. "Molecular Cloning, Expression, and Characterization of A Novel ZebrafishCytosolic Sulfotransferase, SULT5A1." University of Toledo Health Science Campus / OhioLINK, 2016. http://rave.ohiolink.edu/etdc/view?acc_num=mco1470097207.

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Delsol, Anne Aline Germaine. "Microbial 7-hydroxylation of the steroid lithocholic acid : a novel approach to produce bile acids for gallstone therapy." Thesis, University of Exeter, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.297640.

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Book chapters on the topic "Novel Bile Acid Conjugates"

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Kuipers, Folkert, Charles M. A. Bijleveld, C. M. Frank Kneepkens, John Fernandes, and Roel J. Vonk. "Sulfated Lithocholic Acid Conjugates and Cholestasis: Clinical Implications and Protecting Factors." In Liver, Nutrition, and Bile Acids. Springer US, 1985. http://dx.doi.org/10.1007/978-1-4615-9427-7_20.

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Xie, W., and T. Wada. "Novel roles of liver X receptor in bile acid homeostasis and haptobiliary diseases." In Bile Acid Biology and Therapeutic Actions. Springer Netherlands, 2009. http://dx.doi.org/10.1007/978-1-4020-9644-0_16.

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Barton, Derek H. R., Jocelyne Wozniak, and Samir Z. Zard. "A SHORT AND EFFICIENT DEGRADATION OF THE BILE ACID SIDE CHAIN.: SOME NOVEL REACTIONS OF SULPHINES AND α-KETOESTERS." In World Scientific Series in 20th Century Chemistry. WORLD SCIENTIFIC / IMPERIAL COLLEGE PRESS, 1996. http://dx.doi.org/10.1142/9789812795984_0116.

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Conference papers on the topic "Novel Bile Acid Conjugates"

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Šnajdr, Ivan, Zbyněk Janoušek, and Martin Kotora. "Synthesis of novel C-(o-carboranyl)-2-deoxy-D-ribose conjugates." In XVth Symposium on Chemistry of Nucleic Acid Components. Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, 2011. http://dx.doi.org/10.1135/css201112465.

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Sapra, Puja Sapra, Lioudmila Tchistiakova, Russell Dushin, et al. "Abstract 5691: Novel site-specific antibody drug conjugates based on novel amino acid incorporation technology have improved pharmaceutical properties over conventional antibody drug conjugates." In Proceedings: AACR 103rd Annual Meeting 2012‐‐ Mar 31‐Apr 4, 2012; Chicago, IL. American Association for Cancer Research, 2012. http://dx.doi.org/10.1158/1538-7445.am2012-5691.

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Atkins, Jonathan S., Brian G. Keevil та James M. Hawley. "P164 Bile acid malabsorption: the development of a novel serum 7α-hydroxy-4-cholesten-3-one (C4) method to aid diagnosis". У BSG LIVE’23, 19–22 June, ACC Liverpool. BMJ Publishing Group Ltd and British Society of Gastroenterology, 2023. http://dx.doi.org/10.1136/gutjnl-2023-bsg.235.

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Goldman, Aaron, Mohammad Shahidullah, Hwudaurw Chen, Nicholas Delamere, and Katerina Dvorak. "Abstract 4105: Nitric-oxide-mediated inhibition of Na+/H+ exchange (NHE) is a novel mechanism of bile acid induced damage: Relevance to esophageal carcinogenesis." In Proceedings: AACR 101st Annual Meeting 2010‐‐ Apr 17‐21, 2010; Washington, DC. American Association for Cancer Research, 2010. http://dx.doi.org/10.1158/1538-7445.am10-4105.

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Reports on the topic "Novel Bile Acid Conjugates"

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Shapira, Roni, Judith Grizzle, Nachman Paster, Mark Pines, and Chamindrani Mendis-Handagama. Novel Approach to Mycotoxin Detoxification in Farm Animals Using Probiotics Added to Feed Stuffs. United States Department of Agriculture, 2010. http://dx.doi.org/10.32747/2010.7592115.bard.

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T-2 toxin, a toxic product belongs to the trichothecene mycotoxins, attracts major interest because of its severe detrimental effects on the health of human and farm animals. The occurrence of trichothecenes contamination is global and they are very resistant to physical or chemical detoxification techniques. Trichothecenes are absorbed in the small intestine into the blood stream. The hypothesis of this project was to develop a protecting system using probiotic bacteria that will express trichothecene 3-O-acetyltransferase (Tri101) that convert T-2 to a less toxic intermediate to reduce inges
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