Academic literature on the topic 'Novel psychoactive substances (NPSs)'

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Journal articles on the topic "Novel psychoactive substances (NPSs)"

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Chung, Heesun, Jaesin Lee, and Eunmi Kim. "Trends of novel psychoactive substances (NPSs) and their fatal cases." Forensic Toxicology 34, no. 1 (2015): 1–11. http://dx.doi.org/10.1007/s11419-015-0286-5.

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Kelečević, Igor, Ljubica Gugleta, Ana-Marija Vejnović, and Vesna Mijatović Jovin. "New Synthetic Compounds with Psychoactive Action—Preliminary Results Among Primary and High School Students on the Territory of Novi Sad." Medicines 12, no. 1 (2025): 6. https://doi.org/10.3390/medicines12010006.

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Introduction: Novel psychoactive substances (NPSs) are substances not controlled by the United Nations’ 1961 Narcotic Drugs and 1971 Psychotropic Substances convention, which pose a threat to public health. The use of NPSs is growing among recreational drug users. NPSs mimic the effects of the existing illegal drugs; they are used as substitutes for the traditional drugs of use. NPSs are commonly marketed as safe substances. NPS abuse is especially risky among vulnerable individuals, such as children and adolescents. The Aim: This study aims to analyze the knowledge and attitudes of primary an
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Almeida, Ana Sofia, Paula Guedes de Pinho, Fernando Remião, and Carla Fernandes. "Uncovering the Metabolic Footprint of New Psychoactive Substances by Metabolomics: A Systematic Review." Molecules 30, no. 2 (2025): 290. https://doi.org/10.3390/molecules30020290.

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New psychoactive substances (NPSs) emerged in the 2000s as legal alternatives to illicit drugs and quickly became a huge public health threat due to their easy accessibility online, limited information, and misleading labels. Synthetic cannabinoids and synthetic cathinones are the most reported groups of NPSs. Despite NPSs being widely studied, due to their structural diversity and the constant emergence of novel compounds with unknown properties, the development of new techniques is required to clarify their mode of action and evaluate their toxicological effects. Metabolomics has been a usef
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Tan, Fang, Jamie P. Smith, Oliver B. Sutcliffe, and Craig E. Banks. "Regal electrochemistry: sensing of the synthetic cathinone class of new psychoactive substances (NPSs)." Analytical Methods 7, no. 16 (2015): 6470–74. http://dx.doi.org/10.1039/c5ay01820j.

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Regal electrochemistry: discovering new economical electrochemical sensors by utilising a British 2 pence coin; proof-of-concept protocol successfully applied towards the detection of novel psychoactive substances.
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Higgins, Kathryn, Nina O’Neill, Leeanne O’Hara, et al. "Evidence for public health on novel psychoactive substance use: a mixed-methods study." Public Health Research 7, no. 14 (2019): 1–150. http://dx.doi.org/10.3310/phr07140.

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Background Novel psychoactive substances (NPSs) contribute to the public health impact of substance misuse. This report provides research evidence addressing 11 research questions related to NPSs, covering types, patterns and settings of use; supply sources; and implications for policy and practice. Methods The study used a conceptually linked three-phase mixed-methods design with a shared conceptual framework based on multiple-context risk and protective factors. Phase 1 was a quantitative phase involving secondary data analysis of the longitudinal Belfast Youth Development Study (BYDS), a la
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dos Santos, Christiano, and Aline Thais Bruni. "Evaluation of Density Functional Theory-Generated Data for Infrared Spectroscopy of Novel Psychoactive Substances Using Unsupervised Learning." Psychoactives 3, no. 2 (2024): 265–84. http://dx.doi.org/10.3390/psychoactives3020017.

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Novel psychoactive substances (NPSs) are compounds plotted to modify the chemical structures of prohibited substances, offering alternatives for consumption and evading legislation. The prompt emergence of these substances presents challenges in health concerns and forensic assessment because of the lack of analytical standards. A viable alternative for establishing these standards involves leveraging in silico methods to acquire spectroscopic data. This study assesses the efficacy of utilizing infrared spectroscopy (IRS) data derived from density functional theory (DFT) for analyzing NPSs. Va
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Greco, Enrico. "AI Methods for New Psychoactive Substance (NPS) Design and Analysis." Analytica 6, no. 2 (2025): 17. https://doi.org/10.3390/analytica6020017.

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Over the past decade, more than a thousand new psychoactive substances (NPSs) have emerged worldwide. This rapid proliferation of “designer drugs” poses significant challenges for drug control, forensic analysis, and public health. Artificial intelligence (AI) has increasingly been applied to address these challenges in NPS design and analysis. This review provides a comprehensive overview of AI methodologies—including deep learning, generative models, and quantitative structure–activity relationship (QSAR) modeling—and their applications in the synthesis, prediction, and identification of NPS
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Lovrecic, Barbara, Mercedes Lovrecic, Branko Gabrovec, et al. "Non-Medical Use of Novel Synthetic Opioids: A New Challenge to Public Health." International Journal of Environmental Research and Public Health 16, no. 2 (2019): 177. http://dx.doi.org/10.3390/ijerph16020177.

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Background: In the last decade there has been a progressive increase in the use of new psychoactive substances (NPSs) that are not yet under international control. In particular, novel synthetic opioids (NSOs) have reappeared on the recreational drug market in the last few years. As a result, the use of NSOs has increased rapidly. This poses an emerging and demanding challenge to public health. Aim: To raise awareness among clinicians and other professionals about NPSs, especially NSOs, to summarize current knowledge about pharmacological properties, forms of NSO on the market, pattern of use,
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Parrott, A. C., O. Corazza, F. Schifano, et al. "Editorial: Second International Conference on Novel Psychoactive Substances (NPSs): Keynote Addresses and Conference Abstracts." Current Drug Abuse Reviews 6, no. 4 (2014): 255–56. http://dx.doi.org/10.2174/187447370604140616121012.

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Martinotti, G., C. Montemitro, M. Corbo, et al. "Use of Novel Psychoactive Substances and Induced Psychiatric Symptoms: Outcomes From the Eivissa Project." European Psychiatry 41, S1 (2017): S206. http://dx.doi.org/10.1016/j.eurpsy.2017.01.2164.

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IntroductionPolydrug abuse seems to be especially popular in Ibiza, an important market for new psychoactive substances (NPS). The misuse of psychoactive substances can lead to serious psychiatric symptoms.AimsTo evaluate symptoms induced by NPSs and other club drugs, correlating with the main classes of drugs.MethodsNinety subjects (M/F 59/31) admitted in the Psychiatric Unit of Can Misses Hospital (Ibiza) referring a recent intake of substances were enrolled. The following scales were administered: TLFB (Timeline follow-back); Positive and Negative Symptoms Scale (PANSS); Symptom checklist-9
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Dissertations / Theses on the topic "Novel psychoactive substances (NPSs)"

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Simonato, Pierluigi. "Evaluating and expanding knowledge and awareness of health professionals on the consumption and adverse consequences of Novel Psychoactive Substances (NPS) through innovative information technologic tools." Thesis, University of Hertfordshire, 2015. http://hdl.handle.net/2299/16557.

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Background: The rapid diffusion of Novel Psychoactive Substances (NPS) constitutes an important challenge in terms of public health and a novelty in clinical settings, where these compounds may lead to erratic symptoms, unascertained effects and multi-intoxication scenarios, especially in emergency situations. The number of NPS available on the illicit drug market is astonishing: official reports suggest the appearance of a new drug every week. NPS may be enlisted in many different families such as synthetic phenethylamines, tryptamines, cathinones, piperazines, ketamine-like compounds, cannab
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Freeman, Jodie. "Young people's perceptions of novel psychoactive substances." Thesis, University of Wolverhampton, 2018. http://hdl.handle.net/2436/621953.

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Novel Psychoactive Substances (NPS) also known as "legal highs" replicate the effects of illegal substances such as ecstasy and cocaine. The most common NPS reported are stimulants and synthetic cannabinoids. Despite the Psychoactive Ban (2016) recent reports identified the UK as having the largest market of NPS use anywhere in Europe. These substances have a short history of consumption and consequently little is known about their effects and health implications. Despite this, the sale of NPS is easily achieved through the internet and street dealers. Increased reports of negative health cons
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Ritchie, Joseph. "Novel psychoactive substances : implications for UK drugs policy." Thesis, University of Manchester, 2017. https://www.research.manchester.ac.uk/portal/en/theses/novel-psychoactive-substances-implications-for-uk-drugs-policy(e54b7355-3ef5-49b6-8090-3f8458e5018a).html.

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In January 2016, the UK Government legislated for the blanket prohibition of 'new psychoactive substances' (NPS), i.e. unregulated substances that were viewed as similar to already controlled drugs. This followed a six-year period over which these substances have, with increasing speed, been scheduled as drugs, while the harms associated with these substances has increased. This thesis critiques policy here in terms of the way 'NPS' has been represented as a problem for policy makers. Drawing on post-structuralist theory and Science and Technology Studies, it seeks to account for first, how an
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Loi, Barbara. "Neurochemical and neuropharmacological studies on a range of novel psychoactive substances." Thesis, University of Hertfordshire, 2018. http://hdl.handle.net/2299/21073.

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Introduction: Over recent decades, there has been an increase in the availability and use of Novel Psychoactive Substances (NPS) all over the world. They include several classes of chemicals that mimic the effects of illicit drugs and have been purposefully introduced into the market to circumvent or undermine the purpose of legal regulation. Currently, there is information lacking on the pharmacology of these substances; however, the increasing number of cases and outbreaks of intoxications/deaths is becoming a cause for deepening concern. Multi-disciplinary research in the fields of biology,
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Arunotayanun, W. "Chemical and biological studies on natural and synthetic Novel Psychoactive Substances." Thesis, University College London (University of London), 2014. http://discovery.ucl.ac.uk/1432658/.

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Over the past decade, the availability of novel psychoactive substances (NPS), so called “legal highs”, has been increasing dramatically worldwide. Natural products (NP) and synthetic compounds based on NP are amongst the most commonly offered by online vendors. Most synthetic substances have recently been introduced and very little is known about their chemical and biological properties. In this project, 18 novel synthetic NPS were selected and purchased online. The full chemical characterizations using NMR, ESI-MS, HRMS, IR and UV techniques as well as in vitro neurological assays were carri
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Rutherford, Benjamin. "Novel psychoactive substances - Methods for identification, predictive modelling software and an experimental design." Thesis, Rutherford, Benjamin (2017) Novel psychoactive substances - Methods for identification, predictive modelling software and an experimental design. Masters by Research thesis, Murdoch University, 2017. https://researchrepository.murdoch.edu.au/id/eprint/39825/.

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In recent years novel psychoactive substances (NPS) have begun to pose a serious threat to public health and safety. Not only because of their dramatic increase in production and the reported increase of their abuse, but because of their ability to circumvent legislation and the difficulties involved in attempting to identify them. This literature review discusses NPS, the more prevalent classes of NPS, and current methods used for identifying them. The potential for algorithm based predictive modelling software as a technique for identifying NPS will also be investigated.
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Jebadurai, Jeshoor Kumar. "Qualitative research of online drug misuse communities with reference to the novel psychoactive substances." Thesis, University of Hertfordshire, 2013. http://hdl.handle.net/2299/11352.

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Objective: This research aimed at reviewing the information provided by the online drug misuse communities with reference to the available evidence-based literature on the novel psychoactive substances. Methodology: Among hundreds of novel psychoactive substances, four groups (phenethylamines, tryptamines, piperazines and miscellaneous) were selected for the study. Various website drug fora were identified by Google and Yahoo search engines using a set of specific key words. The methods consisted of extracting and analysing qualitative data from the identified website fora. This was also suppl
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Seither, Joshua Zolton. "Application of High Resolution Mass Spectrometry for the Screening and Confirmation of Novel Psychoactive Substances." FIU Digital Commons, 2018. https://digitalcommons.fiu.edu/etd/3823.

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There has been an emergence of novel psychoactive substances (NPS) in forensic casework globally. Although the reported prevalence of these compounds has been relatively low in comparison to traditional drugs of abuse, published case studies suggest that some NPS have significant pharmacological effects that may cause severe impairment and/or death. Because of these effects, it is important that toxicology laboratories have the capability of identifying these compounds to complete a comprehensive toxicological analysis for human performance and post-mortem investigations. Recently, mass spectr
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Mohd, Fauzi Fazlin Binti. "In silico target prediction : applications to traditional medicine and novel psychoactive substances and the extension to biological space." Thesis, University of Cambridge, 2015. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.708743.

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Eckberg, Melanie N. "Forensic Toxicological Screening and Confirmation of 800+ Novel Psychoactive Substances by LC-QTOF-MS and 2D-LC Analysis." FIU Digital Commons, 2018. https://digitalcommons.fiu.edu/etd/3923.

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Novel psychoactive substances (NPS) represent a great challenge to toxicologists due to the ability of illicit drug manufacturers to alter NPS chemical structures quickly and with ease to circumvent legislation regulating their use. Each time a new structure is introduced, there is a possibility that it has not been previously recorded in law enforcement or scientific databases. Many toxicology laboratories use targeted analytical methods that rely on libraries of known compounds to identify drugs in samples. However, these libraries do not include large numbers of NPS which could result in no
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Books on the topic "Novel psychoactive substances (NPSs)"

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Corazza, Ornella, and Andres Roman-Urrestarazu, eds. Novel Psychoactive Substances. Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-60600-2.

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Corazza, Ornella, and Andres Roman-Urrestarazu, eds. Handbook of Novel Psychoactive Substances. Routledge, 2018. http://dx.doi.org/10.4324/9781315158082.

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Corazza, Ornella, and Andres Roman-Urrestarazu. Handbook of Novel Psychoactive Substances: What Clinicians Should Know about NPS. Taylor & Francis Group, 2018.

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Corazza, Ornella, and Andres Roman-Urrestarazu. Handbook of Novel Psychoactive Substances: What Clinicians Should Know about NPS. Taylor & Francis Group, 2018.

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Corazza, Ornella, and Andres Roman-Urrestarazu. Handbook of Novel Psychoactive Substances: What Clinicians Should Know about NPS. Taylor & Francis Group, 2018.

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Handbook of Novel Psychoactive Substances: What Clinicians Should Know about NPS. Taylor & Francis Group, 2018.

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Recent Changes in Drug Abuse Scenario The Novel Psychoactive Substances (NPS) Phenomenon. MDPI, 2019. http://dx.doi.org/10.3390/books978-3-03897-508-3.

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Novel Psychoactive Substances. Elsevier, 2022. http://dx.doi.org/10.1016/c2018-0-04223-1.

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Novel Psychoactive Substances. Elsevier, 2013. http://dx.doi.org/10.1016/c2011-0-04205-9.

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Bowden-Jones, Owen, and Dima Abdulrahim. Club Drugs and Novel Psychoactive Substances. Royal College of Psychiatrists, 2020.

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Book chapters on the topic "Novel psychoactive substances (NPSs)"

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Stiegel, Ute. "Legislating NPS in the European Union." In Novel Psychoactive Substances. Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-60600-2_2.

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Colson, Renaud N. "Harmonizing NPS Legislation Across the European Union: An Utopia." In Novel Psychoactive Substances. Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-60600-2_11.

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Soderholm, Alexander. "Regulating NPS in the Middle East: A Critical Juncture." In Novel Psychoactive Substances. Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-60600-2_6.

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Corazza, Ornella, Hui Yun Chan, and Andres Roman-Urrestarazu. "NPS: Moving from Blanket Prohibition to a Functionalist Approach." In Novel Psychoactive Substances. Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-60600-2_9.

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Collins, John. "Regulation as Global Drug Governance: How New Is the NPS Phenomenon?" In Novel Psychoactive Substances. Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-60600-2_3.

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Tettey, Justice N., and Sabrina Levissianos. "The Global Emergence of NPS: An Analysis of a New Drug Trend." In Novel Psychoactive Substances. Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-60600-2_1.

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Wilkins, Chris, Marta Rychert, Bogumiła Byrska, Marie Claire Van Hout, Ornella Corazza, and Andres Roman-Urrestarazu. "Exploring Innovative Policy Responses to NPS and ‘Legal Highs’ in New Zealand, Poland, Republic of Ireland and the UK." In Novel Psychoactive Substances. Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-60600-2_5.

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Shafi, Abu, Paul Gallagher, Bhaskar Punukollu, and Giovanni Martinotti. "NPS Policy Pitfalls: The Implementation and Management Challenges Within the Prison, Police and Health Services in the United Kingdom." In Novel Psychoactive Substances. Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-60600-2_8.

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Prilutskaya, Maria, and Hui Yun Chan. "Finding Novel Policy Response to the Challenge of NPS in Kazakhstan: Reconsidering Existing Policy and the Work of Health Professionals." In Novel Psychoactive Substances. Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-60600-2_7.

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Kapitány-Fövény, Máté, Aviv M. Weinstein, and Zsolt Demetrovics. "NPS." In Handbook of Novel Psychoactive Substances. Routledge, 2018. http://dx.doi.org/10.4324/9781315158082-3.

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Conference papers on the topic "Novel psychoactive substances (NPSs)"

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"PV-086 - EL RETO DE LAS NUEVAS DROGAS PSICOACTIVAS EN TRASTORNO MENTAL GRAVE." In 24 CONGRESO DE LA SOCIEDAD ESPAÑOLA DE PATOLOGÍA DUAL. SEPD, 2022. http://dx.doi.org/10.17579/abstractbooksepd2022.pv086.

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OBJETIVOS Explorar la información disponible hasta el momento sobre el consumo de Nuevas Drogas Psicoactivas (NDP) en personas con Trastorno Mental Grave (TMG), así como detectar los retos de cara a mejorar el conocimiento en este campo. MATERIAL Y MÉTODOS Se ha realizado una revisión de estudios científicos hasta 2022 sobre el tema a tratar en PubMed y MedLine, incluyendo estudios en inglés que indagasen sobre el uso de NDP en adultos con TMG. Palabras clave: “Novel/New Psychoactive Substances/NPS”, “Schizophrenia”, “bipolar disorder”, “Severe Mental Illness/SMI”. También se han consultado re
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Akgür, Serap Annette. "Controlled Psychoactive Substances and Workplace Drug Testing." In Panel on "Effective Drug Control Strategies in Northern Cyprus: Challenges and Opportunities in 2024". Emanate Publishing House Ltd., 2024. http://dx.doi.org/10.70020/ehass.2024.7.3.

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The use of psychoactive substances has been on the rise around the world. Psychoactive substances, such as amphetamine, codeine, cocaine, marijuana, methamphetamine, etc. have potent pharmacological activities that cause cognitive and behavioral disorders. New psychoactive substances (NPSs) have also emerged that produce similar effects to those induced by illegal drugs, such as cocaine, cannabis, and amphetamines, but are not strictly regulated by international conventions. The rapid emergence since the mid-2000s of a large and diverse range of substances termed new psychoactive substances or
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Reports on the topic "Novel psychoactive substances (NPSs)"

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Chapman, Stephen. Novel Psychoactive Spectra: NMR of (mostly) Novel Psychoactive Substances. Isomer Design, 2017. http://dx.doi.org/10.16889/isomerdesign-6.

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