Relevant bibliographies by topics / Novozym

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Academic literature on the topic 'Novozym'

Author: Grafiati
Published: 4 June 2021
Last updated: 1 February 2022

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Journal articles on the topic "Novozym"

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Ortiz, Claudia, María Luján Ferreira, Oveimar Barbosa, José C. S. dos Santos, Rafael C. Rodrigues, Ángel Berenguer-Murcia, Laura E. Briand, and Roberto Fernandez-Lafuente. "Novozym 435: the “perfect” lipase immobilized biocatalyst?" Catalysis Science & Technology 9, no. 10 (2019): 2380–420. http://dx.doi.org/10.1039/c9cy00415g.

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Nyari, Nádia Ligianara Dewes, Josiane B. da Silva, Tainára Orlando, Suelen P. Piazza, Rogério L. Cansian, Débora De Oliveira, Jamile Zeni, Rogério M. Dallago, and Natália Paroul. "Processo enzimático para produção de acetato de isoamila livre de solvente orgânico." Brazilian Journal of Food Research 10, no. 1 (December 31, 2019): 129. http://dx.doi.org/10.3895/rebrapa.v10n1.9037.

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Nos últimos anos, a crescente demanda por produtos naturais na indústria de alimentos incentivou esforços notáveis no desenvolvimento de processos biotecnológicos para a produção de compostos aromatizantes. O presente estudo relata a maximização da produção de acetato de isoamila por esterificação de álcool isoamílico e ácido acético em um sistema isento de solventes usando duas lipases diferentes como catalisador. A lipase Novozyme NZL-102-LYO-HQ (Candida antarctica B imobilizada em poliuretano – PU) foi comparada com a comercializada Novozym 435 e foi avaliada em termos de desempenho, rendimento e estabilidade operacional. Os efeitos nas taxas de reação mostraram valores maximizados diferentes, empregando esses dois catalisadores, no entanto as condições reacionais no que se refere a razão molar do substrato (ácido acético: álcool isoamílico), massa de catalisador e tempo de reação foram distintos. Embora Novozym 435 exibisse maior conversão inicial com relação a NZL-102-LYO-HQ, ambas formas lineares e apresentaram uma conversão superior a 90%. Para o catalisador Novozym 435 (razão molar 1:3 de ácido acético:álcool isoamílico e massa de catalisador 17% em peso) em 240 minutos e a Novozyme NZL-102-LYO-HQ (Candida antarctica B imobilizada em poliuretano – PU) (razão molar 1:5 de ácido acético:álcool isoamílico e massa de catalisador 7% em peso) em 360 minutos de reação com 10 ciclos de reutilização. Sendo assim esses resultados são de grande valia para a produção industrial, sobretudo na síntese de ésteres de cadeia média, como acetato de isoamila em diferentes preparações enzimáticas, tornando uma fonte promissora comparado com estudo apresentados na literatura aberta.
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Manurung, Renita, and Alwi Gery Siregar. "Reusability of the Deep Eutectic Solvent - Novozym 435® Enzymes System in Transesterification from Degumming Palm Oil." Advanced Engineering Forum 35 (February 2020): 9–17. http://dx.doi.org/10.4028/www.scientific.net/aef.35.9.

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In this study, deep eutectic solvent (DES) used as co solvent for enzymatic biodiesel production from degumming palm oil (DPO). DES is formed from the salt compound choline-chloride (ChCI) with glycerol at 1:2 molar ratio. Furthermore, the effectiveness of the DES was tested by enzymatic reactions using novozym 435® for the production of palm biodiesel with raw materials DPO. The use of enzymes with the DES system can maintain the activity and stability of the novozyme enzyme measured by the yield produced until the 10th usage produces biodiesel yield > 99% with a concentration of DES 0.5% with a molar ratio of 0.5% water. Spectra of DES ChCI:glycerol and ChCI:glycerol:water characterized by FTIR, morphological structure novozym by characterized SEM and then biodiesel product analyzed by GC-MS. This shows that the ChCI:glycerol:water system in enzymatic biodiesel production has good potential to maintain enzyme activity and stability.
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Zou, Cheng, You Yan Liu, Yi Ming Qin, Ai Xing Tang, and Li Na Lan. "Chemoenzymatic Epoxidation of α-Pinene Catalyzed by Novozym 435." Advanced Materials Research 634-638 (January 2013): 896–900. http://dx.doi.org/10.4028/www.scientific.net/amr.634-638.896.

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The synthesis of α-pinene oxide mediated by Novozym 435 (lipase from Candida antarctica) in a three-phase system was studied in this work. Novozyme 435 catalysed the formation of peroxyoctanoic acid directly from octanoic acid and hydrogen peroxide, which was then applied for in situ oxidation of α-pinene. The highest conversion of a-pinene (approximately 80%) was obtained when the reaction was performed at 30°C and initial hydrogen peroxide concentration in the water phase was set to be 30%. The parameters affecting the lipase activity were also investigated，where the peracid generated in organic phase was obvserved to greatly inactivate the enzyme compared to other components in the organic phase.
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Prošková, A., Z. Kopicová, J. Kučera, and L. Škarková. "Lipase-catalyzed transesterification of rendering plant fat – Short Communication." Research in Agricultural Engineering 56, No. 3 (August 26, 2010): 122–25. http://dx.doi.org/10.17221/40/2009-rae.

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Soluble lipase (Lipozyme CALB L) was immobilized by covalent bond to chitosan pellets prepared from Aspergillus niger mycelium. This immobilized enzyme was compared with commercial immobilized lipase of the same origin (Novozym 435). Novozym 435 is also lipase CALB L commercially immobilized by sorption on poly-(methyl acrylate). Novozym 435 shows much higher conversion of rendering plant fat in methanol under optimum conditions, having, at the same time, lower optimum temperature and lower stability at higher temperature. Lipozyme CALB L immobilized on chitosan leads to a low conversion, regardless its higher thermal stability. Novozym 435 gives conversion of about 50% of theoretical value, which is in good accordance with basically catalyzed transesterification of rendering plant fat described elsewhere. Lipozyme CALB L immobilized on chitosan gives conversion of about 10% of theoretical value only. The use of Novozym 435 in two-step system (enzyme-acid) seems to be more convenient compared with traditional two-step system (base-acid)
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Dalla Rosa, Clarissa, Débora de Oliveira, and José Vladimir Oliveira. "The role of organic solvent amount in the lipase-catalyzed biodiesel production." Food Science and Technology 30, no. 1 (February 26, 2010): 76–78. http://dx.doi.org/10.1590/s0101-20612010005000008.

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This research note addresses the role of organic solvent amount in the production of fatty acid ethyl esters from soybean oil. N-hexane was chosen as solvent and two commercial immobilized lipases as catalysts, Novozym 435 and Lipozyme IM. The reactions were conducted in 6 hours, varying the solvent to oil ratio from zero to 50 (v/wt) and adopting adopting for Novozym 435: 65 ºC, enzyme concentration (E, wt%) = 5, oil to ethanol molar ratio (R) = 1:10, water addition (H, wt%) = 0, and for Lipozyme IM: 35 ºC, E = 5 wt%, R = 1:3, H = 10 wt%. For Lipozyme IM, an increase in solvent amount is shown to lead to an enhancement of reaction conversion, while a negligible effect was found for Novozym 435. When using 30 mL of solvent the reaction conversions were 88% for Lipozyme IM and 15% for Novozym 435.
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Aguieiras, Erika C. G., Cláudia O. Veloso, Juliana V. Bevilaqua, Danielle O. Rosas, Mônica A. P. da Silva, and Marta A. P. Langone. "Estolides Synthesis Catalyzed by Immobilized Lipases." Enzyme Research 2011 (June 20, 2011): 1–7. http://dx.doi.org/10.4061/2011/432746.

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Estolides are vegetable-oil-based lubricants obtained from oleic acid or any source of hydroxy fatty acids. In this work, the estolides synthesis from oleic acid and methyl ricinoleate (biodiesel from castor oil), using immobilized commercial lipases (Novozym 435, Lipozyme RM-IM, and Lipozyme TL-IM) in a solvent-free medium was investigated. Acid value was used to monitor the reaction progress by determining the consumption of acid present in the medium. Novozym 435 showed the best performance. Water removal improved the conversion. Novozym 435 was more active at atmospheric pressure. Novozym 435 was reused four times with conversion reaching 15% after the fourth reaction at 80°C. Estolides produced under the reaction conditions used in this work presented good properties, such as, low temperature properties as pour point (−24°C), viscosity (23.9 cSt at 40°C and 5.2 cSt at 100°C), and viscosity index (153).
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Moreira, Katerine S., Lourembergue S. Moura Júnior, Rodolpho R. C. Monteiro, André L. B. de Oliveira, Camila P. Valle, Tiago M. Freire, Pierre B. A. Fechine, et al. "Optimization of the Production of Enzymatic Biodiesel from Residual Babassu Oil (Orbignya sp.) via RSM." Catalysts 10, no. 4 (April 9, 2020): 414. http://dx.doi.org/10.3390/catal10040414.

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Residual oil from babassu (Orbignya sp.), a low-cost raw material, was used in the enzymatic esterification for biodiesel production, using lipase B from Candida antarctica (Novozym® 435) and ethanol. For the first time in the literature, residual babassu oil and Novozym® 435 are being investigated to obtain biodiesel. In this communication, response surface methodology (RSM) and a central composite design (CCD) were used to optimize the esterification and study the effects of four factors (molar ratio (1:1–1:16, free fatty acids (FFAs) /alcohol), temperature (30–50 °C), biocatalyst content (0.05–0.15 g) and reaction time (2–6 h)) in the conversion into fatty acid ethyl esters. Under optimized conditions (1:18 molar ratio (FFAs/alcohol), 0.14 g of Novozym® 435, 48 °C and 4 h), the conversion into ethyl esters was 96.8%. It was found that after 10 consecutive cycles of esterification under optimal conditions, Novozym® 435 showed a maximum loss of activity of 5.8%, suggesting a very small change in the support/enzyme ratio proved by Fourier Transform Infrared (FTIR) spectroscopy and insignificant changes in the surface of Novozym® 435 proved by scanning electron microscopy (SEM) after the 10 consecutive cycles of esterification.
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Sørensen, Annette, Peter Stephensen Lübeck, Mette Lübeck, Philip Johan Teller, and Birgitte Kiær Ahring. "β-Glucosidases from a new Aspergillus species can substitute commercial β-glucosidases for saccharification of lignocellulosic biomass." Canadian Journal of Microbiology 57, no. 8 (August 2011): 638–50. http://dx.doi.org/10.1139/w11-052.

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β-Glucosidase activity plays an essential role for efficient and complete hydrolysis of lignocellulosic biomass. Direct use of fungal fermentation broths can be cost saving relative to using commercial enzymes for production of biofuels and bioproducts. Through a fungal screening program for β-glucosidase activity, strain AP (CBS 127449, Aspergillus saccharolyticus ) showed 10 times greater β-glucosidase activity than the average of all other fungi screened, with Aspergillus niger showing second greatest activity. The potential of a fermentation broth of strain AP was compared with the commercial β-glucosidase-containing enzyme preparations Novozym 188 and Cellic CTec. The fermentation broth was found to be a valid substitute for Novozym 188 in cellobiose hydrolysis. The Michaelis–Menten kinetics affinity constant as well as performance in cellobiose hydrolysis with regard to product inhibition were found to be the same for Novozym 188 and the broth of strain AP. Compared with Novozym 188, the fermentation broth had higher specific activity (11.3 U/mg total protein compared with 7.5 U/mg total protein) and also increased thermostability, identified by the thermal activity number of 66.8 vs. 63.4 °C for Novozym 188. The significant thermostability of strain AP β-glucosidases was further confirmed when compared with Cellic CTec. The β-glucosidases of strain AP were able to degrade cellodextrins with an exo-acting approach and could hydrolyse pretreated bagasse to monomeric sugars when combined with Celluclast 1.5L. The fungus therefore showed great potential as an onsite producer for β-glucosidase activity.
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Aguilera-Oviedo, Johanna, Edinson Yara-Varón, Mercè Torres, Ramon Canela-Garayoa, and Mercè Balcells. "Sustainable Synthesis of Omega-3 Fatty Acid Ethyl Esters from Monkfish Liver Oil." Catalysts 11, no. 1 (January 13, 2021): 100. http://dx.doi.org/10.3390/catal11010100.

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The search for economic and sustainable sources of polyunsaturated fatty acids (PUFAs) within the framework of the circular economy is encouraged by their proven beneficial effects on health. The extraction of monkfish liver oil (MLO) for the synthesis of omega-3 ethyl esters was performed to evaluate two blending systems and four green solvents in this work. Moreover, the potential solubility of the MLO in green solvents was studied using the predictive simulation software COnductor-like Screening MOdel for Realistic Solvents (COSMO-RS). The production of ethyl esters was performed by one or two-step reactions. Novozym 435, two resting cells (Aspergillus flavus and Rhizopus oryzae) obtained in our laboratory and a mix of them were used as biocatalysts in a solvent-free system. The yields for Novozym 435, R. oryzae and A. flavus in the one-step esterification were 63, 61 and 46%, respectively. The hydrolysis step in the two-step reaction led to 83, 88 and 93% of free fatty acids (FFA) for Novozym 435, R. oryzae and A. flavus, respectively. However, Novozym 435 showed the highest yield in the esterification step (85%), followed by R. oryzae (65%) and A. flavus (41%). Moreover, selectivity of polyunsaturated fatty acids of R. oryzae lipase was evidenced as it slightly esterified docosahexaenoic acid (DHA) in all the esterification reactions tested.
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Dissertations / Theses on the topic "Novozym"

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Rodriguez, De Rodriguez Maria Del Pilar. "Production de biodiesel ?? partir d'une huile mod??le de microalgues par voie de catalyse enzymatique h??t??rog??ne." Mémoire, Universit?? de Sherbrooke, 2014. http://savoirs.usherbrooke.ca/handle/11143/111.

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Le biodiesel, consid??r?? comme une solution pour remplacer le p??trodiesel est un sujet de recherche mondial. Un des principaux probl??mes associ??s au d??veloppement industriel du biodiesel est la source de mati??re premi??re ainsi que le proc??d?? de transformation. Ainsi, la pr??sente ??tude a pour but de trouver une source de mati??re premi??re durable pour la production industrielle de biodiesel et de d??terminer le proc??d?? de transformation de la mati??re premi??re, le plus appropri??, ainsi que les meilleures conditions op??ratoires. Durant la premi??re ??tape de ce projet, une source de mati??re premi??re durable a ??t?? s??lectionn??e : les microalgues. Le proc??d?? de transformation ??tudi?? est la transest??rification enzymatique. L???huile d???olive, huile ayant une composition en acides gras similaires ?? celle de l???huile de la microalgue Chlorella protothecoides, a ??t?? choisie pour effectuer les r??actions. Pendant la deuxi??me ??tape, le proc??d?? de standardisation de la r??action (bior??acteur de 5 mL) consistait ?? faire varier : le type de catalyseur (lipases de Candida antarctica (Novozym?? 435) et de Thermomyces lanuginosus (TL I150)), la concentration du catalyseur (7 ?? 14 % m/mhuile), la temp??rature de r??action (25 ?? 50 ??C) et le ratio molaire alcool:huile (3:1 ?? 4:1) ; la vitesse d???agitation ??tant de 150 rpm pour toutes les r??actions. Des techniques d???optimisation telle que la preincubation de l???enzyme ont ??t?? ??galement essay??es. Le rendement en esters alkyliques de la r??action de transest??rification enzymatique de l???huile en fonction du temps est la variable de contr??le pour toutes les r??actions. La standardisation des variables du proc??d?? a ??t?? faite en fonction de la r??duction du temps de r??action et du rendement en esters alkyliques. Un rendement ??lev?? en esters alkyliques de 92 % (m/m) a ??t?? obtenu sous les conditions op??ratoires suivantes : une concentration de catalyseur (TL I150) de 7 % (m/mhuile), une temp??rature de r??action de 25 ??C, un ratio molaire alcool:huile de 3:1 et un temps de r??action de 4 h ; la lipase a ??t?? preincub??e pendant 6 h avant la r??action de transest??rification. Le temps de r??action, un des param??tres importants lors du proc??d?? de standardisation des variables, a ??t?? r??duit de 24 ?? 4 h. Un autre param??tre significatif de la r??action est la temp??rature : une temp??rature de 25 ??C a ??t?? utilis??e; cette temp??rature de r??action est faible et rend le proc??d?? au niveau industriel plus attrayant.
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Rodriguez, De Rodriguez Maria Del Pilar. "Production de biodiesel à partir d'une huile modèle de microalgues par voie de catalyse enzymatique hétérogène." Mémoire, Université de Sherbrooke, 2014. http://savoirs.usherbrooke.ca/handle/11143/111.

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Le biodiesel, considéré comme une solution pour remplacer le pétrodiesel est un sujet de recherche mondial. Un des principaux problèmes associés au développement industriel du biodiesel est la source de matière première ainsi que le procédé de transformation. Ainsi, la présente étude a pour but de trouver une source de matière première durable pour la production industrielle de biodiesel et de déterminer le procédé de transformation de la matière première, le plus approprié, ainsi que les meilleures conditions opératoires. Durant la première étape de ce projet, une source de matière première durable a été sélectionnée : les microalgues. Le procédé de transformation étudié est la transestérification enzymatique. L’huile d’olive, huile ayant une composition en acides gras similaires à celle de l’huile de la microalgue Chlorella protothecoides, a été choisie pour effectuer les réactions. Pendant la deuxième étape, le procédé de standardisation de la réaction (bioréacteur de 5 mL) consistait à faire varier : le type de catalyseur (lipases de Candida antarctica (Novozym® 435) et de Thermomyces lanuginosus (TL I150)), la concentration du catalyseur (7 à 14 % m/mhuile), la température de réaction (25 à 50 °C) et le ratio molaire alcool:huile (3:1 à 4:1) ; la vitesse d’agitation étant de 150 rpm pour toutes les réactions. Des techniques d’optimisation telle que la preincubation de l’enzyme ont été également essayées. Le rendement en esters alkyliques de la réaction de transestérification enzymatique de l’huile en fonction du temps est la variable de contrôle pour toutes les réactions. La standardisation des variables du procédé a été faite en fonction de la réduction du temps de réaction et du rendement en esters alkyliques. Un rendement élevé en esters alkyliques de 92 % (m/m) a été obtenu sous les conditions opératoires suivantes : une concentration de catalyseur (TL I150) de 7 % (m/mhuile), une température de réaction de 25 °C, un ratio molaire alcool:huile de 3:1 et un temps de réaction de 4 h ; la lipase a été preincubée pendant 6 h avant la réaction de transestérification. Le temps de réaction, un des paramètres importants lors du procédé de standardisation des variables, a été réduit de 24 à 4 h. Un autre paramètre significatif de la réaction est la température : une température de 25 °C a été utilisée; cette température de réaction est faible et rend le procédé au niveau industriel plus attrayant.
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Goma, Doncescu Nathalie. "Synthèse enzymatique de cires en milieux concentrés." Compiègne, 1997. http://www.theses.fr/1997COMP1022.

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Une voie d'accès aux cires est proposée et évaluée par catalyse enzymatique. Elle s'effectue à partir d'un mélange d'esters méthyliques (colza/tournesol) et d'alcool stéarique via une réaction de transestérification en présence de Lipozyme. L'originalité de ces travaux réside dans la simple mise en oeuvre des substrats et de l'enzyme immobilisée en réacteur contrôlé en température sans addition de solvant organique. L'obtention de rendements élevés est réalisée avec une faible quantité d'enzyme, des taux de conversion de 80 à 100 %, suivant le rapport molaire des substrats sont obtenus en 2 heures à 60 °C. L'influence du rapport molaire 1 oléate de méthyle : alcool stéarique 1 ainsi que de la température sont étudiés et donnent des valeurs optimales pour le ratio 1 1 : 0,5 1 à 60 °C. L'effet inhibiteur de l'alcool stéarique a été mis en évidence par une étude cinétique. La présence de limitations diffusionnelles de type externes a été montrée (milieu réactionnel/surface du support enzymatique). Après l'évaluation, l'optimisation de la mise en oeuvre a permis de faire progresser les performances. La validation du procédé a été vérifiée à plus grande échelle. Une autre enzyme immobilisée a été testée, le Novozym, qui permet d'obtenir un rendement optimal pour le mélange équimolaire. Cet avantage conduit à un produit exempt de substrat en fin de réaction. De plus, l'efficacité catalytique du Novozym (0,213 miri-1) est supérieure à celle du Lipozyme (0,144 miri ). Enfin, la réaction de transestérification a été examinée avec élimination simultanée du co-produit, le méthanol, au fur et à mesure de sa formation. Les deux préparations enzymatiques ont été testées en réacteurs fermé, ouvert et sous vide. Quelque soient les conditions, la réaction a'alcoolyse est plus rapide si le méthanol produit pendant la réaction est retiré du mélange. L'utilisation des ratios S1/S2=1 convient à un procédé particulièrement simple puisqu'il amène une production de cire exempte de co-substrat
Wax ester production has been investigated. Transesterification reaction has been realized from methyl ester mix (vegetable oils of rape and sunflower) and stearyl alcohol with Lipozyme. The alcoholysis reaction is controlled in solvent-free medium that is exclusively composed of the reactants and the enzyme. The transesterification is performed by simply mixing the two substrates in a temperature-controlled water bath under stirring. High yields are obtained with a Iow amount of Lipozyme, rate conversion from 80 to 100 % depending on molar ratio in 2 hours at the temperature of 60 °C. The balance between optimal working temperature and the molar ratio of substrates in such a complex medium appears to be 60 °C with a molar ratio I methyl oleate : stearyl alcohol of I 1: 0,5I. Substrate inhibition due to stearyl alcohol has been confirmed by a study of kinetic parameters. More, external diffusional limitations have been showed (reaction medium/surface of enzymatic support). Then, after evaluation, optimization of process has been performed. The validation of results has been verified at a large-scale process. Another enzymatic preparation has been tested. Novozym permits to obtain optimal yield for the equimolar mixing. This advantage directly led to a final product exempted of substrates. More, catalytic efficiency of Novozym (0,213 min-1) is higher than catalytic efficiency of Lipozyme (0,144 min-1). Finally, transesterification reaction has been examined with the elimination of the co-product formed, the methanol in proportion of producing. The two immobilised enzymes have been investigated in covered reactor, cap-opened reactor and under vacuum. More rapid is the methanol elimination, higher is the rate production of stearyl oleate. The use of substrate ratio S 1/Sz=l leads to direct stearyl waxes production exempted from reactive using simple but efficient way
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Yan, Jialu. "Enzymatic Polyesterification to Produce Functionalized Poly(Lactic Acid) and Poly(n-Hydroxyalkanoic Acid)s." University of Akron / OhioLINK, 2013. http://rave.ohiolink.edu/etdc/view?acc_num=akron1375415868.

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Ytredal, Espen Sveine. "Bruk av lipasen Candida antarctica (Novozym 435) som biokatalysator for etanollyse av sild- og selolje, analysert ved 13C NMR spektroskopi, gasskromatografi og tynnsjiktkromatografi med flammeioniseringsdetektor." Thesis, Norges teknisk-naturvitenskapelige universitet, Institutt for bioteknologi, 2013. http://urn.kb.se/resolve?urn=urn:nbn:no:ntnu:diva-21770.

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De flerumettede omega-3 fettsyrene eikosapentaensyre (EPA) og dokosaheksaensyre (DHA) har fått økt oppmerksomhet på grunn av dokumenterte helseeffekter mot hjerte- og karsykdommer. Fettsyrene finnes normalt som etylestere eller triasylglyseroler i oppkonsentrerte fiskeolje produkter. Industrielt produseres fiskeolje produkter ved kjemisk transesterifisering, en prosess som krever høy temperatur og bruk av kjemikalier. Lipaser har i nyere tid fått gradvis økt oppmerksomhet på grunn av deres milde betingelser og spesifisitet ved bruk som biokatalysator under lipid modifikasjon. Denne oppgaven har som hovedformål å studere muligheten for å benytte lipase som biokatalysator ved transesterifiseringsreaksjon av sild- og selolje for produksjon av etylester. Den ikke-spesifikke immobiliserte lipasen Candida antarctica (Novozym 435) er benyttet som biokatalysator for reaksjonen. Reaksjonens progresjon er studert ved bruk av kjernemagnetisk resonans(13C NMR) som etter min beste kjennskap ikke er benyttet i stor grad for studie av etanollyse. Fettsyresammensetningen og fettsyreposisjoneringen på glyserolmolekylet til sild- og selolje er bestemt ved gasskromatografi (GC) og 13C NMR. Temperatur og etanolmengdens innvirkning og optimale betingelser er bestemt ved tynnsjiktkromatografi med flammeioniseringsdetektor (TLC-FID). I sild- og selolje utgjør enumettede fettsyrer den største andelen fettsyrer med henholdsvis 59 og 59% av totale mengde fettsyrer. De flerumettede omega-3 fettsyrene utgjør henholdsvis 16 og 23% for sild- og selolje. Selolje har fettsyrene EPA og DHA esterifisert til sn-1,3 posisjon ved >95%. Sildeolje har DHA esterifisert til sn-2 posisjon ved >95% og EPA esterifisert 49% til posisjon sn-1,3 og 51% til posisjon sn-2. Optimale reaksjonsbetingelser er funnet for etanollysereaksjonen med hensyn til temperatur og etanolmengde. Ved bruk av sildolje under støkiometrisk molarforhold etanol til olje er økende temperatur funnet å øke etylester dannelseshastigheten. Det er vist at 60oC gir en lavere reaksjonshastighet enn optimaltemperaturen 50oC. Dette kan forklares av redusert lipaseaktivitet som resultat av massetransportbegrensninger. Etanolmengdens innvirkning på etanollyse reaksjonen er funnet å gi økt etylester dannelseshastighet, ved økt mengde av etanol i systemet. Ved overskudd av etanol er det funnet at temperaturen ikke har samme innvirkning, som under støkiometrisk molarforhold etanol til olje. På bakgrunn av disse resultatene er 50oC funnet å være optimaltemperatur ved støkiometrisk molarforhold etanol. Ved overskudd av etanol er funnet at 30oC er den mest passende temperatur. 13C NMR er den eneste analysemetoden som gir multi-komponent informasjon i et steg. I denne oppgaven er teknikken benyttet for analyse av reaksjonsprogresjonen til etanollysereaksjonen under de optimaliserte betingelsene. Ved støkiometrisk molarforhold etanol til olje viser lipasen spesifisitet mot sn-1,3 posisjonene på glyserolmolekylet i sild- og selolje. For selolje viser lipasen høyere aktivitet mot fettsyren EPA enn DHA. Undersøkelsen gjort ved 50oC viser endring i sammensetningen asylglyserol gjennom reaksjonsforløpet fra 2MAG og 1,2DAG til 1MAG og 1,3DAG som kan forklares av intramolekylær asylmigrering. Analyse av reaksjonsprogresjonen til etanollysereaksjonen utført med overskudd av etanol og 30oC viser at lipasen fortsatt uttrykker spesifisitet mot sn-1,3 posisjonene på glyserolmolekylet. For selolje viser lipasen også økt aktivitet mot fettsyren EPA sammenlignet med DHA. Analysen viser imidlertid ikke endring i sammensetning asylglyseroler over reaksjonsforløpet noe som tilsier at det ved lavere temperatur ikke forekommer intramolekylær asylmigrering.
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6

Lopes, Catarina Alexandra dos Santos. "Produção de lipidos estruturados dietéticos por catálise enzimática a partir de óleo de bagaço de azeitona." Master's thesis, ISA, 2020. http://hdl.handle.net/10400.5/21311.

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Mestrado em Engenharia Alimentar / Instituto Superior de Agronomia. Universidade de Lisboa
O presente estudo teve como objetivo produzir lípidos dietéticos do tipo MLM, por catálise enzimática, a partir de óleo de bagaço de azeitona bruto (OBA), de elevada acidez (20,2%), com teores elevados de produtos de oxidação (K232: 6,98 e K270:2,22) e de clorofilas totais (91 mg/kg feofitina a). Os MLM são triacilgliceróis (TAG) que contêm ácidos gordos de cadeia longa (L) em posição sn-2 e ácidos gordos de cadeia média (M) nas posições sn-1,3. Os MLM foram obtidos por acidólise de OBA com ácido caprílico (C8:0) ou cáprico (C10:0). As reações decorreram em descontínuo, em meio livre de solvente, razão molar de 1:2 (OBA:M), a 50 ºC durante 48 h. Utilizou-se como fonte de ácidos gordos de cadeia longa o OBA bruto e após remoção, por adsorção, de 99% de pigmentos clorofilinos. Testaram-se como biocatalisadores as lipases imobilizadas comerciais de Rhizomucor miehei (Lipozyme RM IM) (sn-1,3 seletiva) e de Candida antarctica (Novozym 435), e lipases comerciais líquidas (Novozym 388, Lipozyme CALB L e Novozym 735) por nós imobilizadas nos suportes sintéticos Lewatit VP OC 1600 e Accurel MP 1000. A Lipozyme RM IM e Novozym 435 catalisaram preferencialmente a formação de novos TAG com C10:0 em detrimento de C8:0, com rendimento em novos TAG de 56,6% (m/m) e 48,7% (m/m) a partir do óleo bruto e óleo descorado, respetivamente, por ação da Lipozyme RM IM, 52,5% (m/m) e 53,6% (m/m) a partir de óleo bruto e descorado, respetivamente, por ação de Novozym 435. O rendimento em novos TAG (%) obtidos por acidólise catalisada por Novozym 435 diminuiu com o aumento de temperatura (60 ºC). Os rendimentos em novos TAG obtidos por acidólise catalisada pelas lipases imobilizadas no laboratório foram inferiores a 12,6%
N/A
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7

Alves, Da Costa Cardoso Ligia. "Identification de facteurs opératoires influents en vue d'une production microbienne optimale de torularhodine et de sa fonctionnalisation enzymatique, à partir d'études cinétiques." Thesis, Vandoeuvre-les-Nancy, INPL, 2008. http://www.theses.fr/2008INPL082N/document.

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Ce travail a eu pour objectif de déterminer les conditions optimales de production d’un caroténoïde original, la torularhodine, par Sporobolomyces ruberrimus, cultivée en réacteur discontinu. Cette souche est capable d’utiliser le glycérol technique comme source de carbone et d’énergie pour sa croissance et pour la production de caroténoïdes. D’abord, il s’est agi d’identifier les facteurs opératoires majeurs qui sont susceptibles d’avoir une influence sur la production de la torularhodine, au travers d’une étude préliminaire. L’identification expérimentale de ces facteurs d’action - la température, le taux d’oxygène dissous et la supplémentation en acide oléique - a été validée statistiquement, à des degrés divers, avant d’engager une étape d’optimisation par la construction d’un plan d’expériences multicritère. Celui-ci a conduit à l’établissement de modèles polynômiaux du second degré pour représenter l’effet conjugué des facteurs retenus et permettre la prédiction des valeurs de µmax et de concentration de torularhodine rapportée à la biomasse. Cette étude a alors été consacrée à un essai de fonctionnalisation de la torularhodine, à partir de sa fonction carboxylique, en vue de la stabilisation de la molécule dont l’activité antioxydante est élevée. L’acylation enzymatique de la lysine par la torularhodine a été envisagée. Les conditions d’acylation par la lipase B de C. antarctica ont été déterminées avec un caroténoïde modèle, la bixine. Le produit dérivé obtenu après transacylation a été purifié et a montré une activité antiradicalaire supérieure à celle de la bixine. Ces résultats permettent d’envisager la synthèse de peptides acylés avec ce type de caroténoïdes
The aim of this work was to determine the optimum of an original carotenoid, the torularhodin, produced by Sporobolomyces ruberrimus, in batch culture. A very interesting characteristic of this strain is its ability to consume raw glycerol as a carbon and energy source for microbial growth and carotenoid production. In the fist part of this study, the identification of operating parameters that have an influence on the optimum torularhodin production, was achieved. Experimental assays reinforced by a statistical study allowed to identify temperature, dissolved oxygen pressure and oleic acid supplementation, as the major parameters of influence, and then the integration of these data was performed for the construction of a multiobjective optimization based on a multicriteria experimental design. The establishment of a mathematical model of a second degree polynomial type was developed for the prediction of the values of µmax and of the torularhodin concentration reported to biomass. In the last part, considering that torularhodin has an important antioxidant property and it exhibits a free carboxyl acid function which can be used as acyl agent, a study of its structure modifying by an enzymatic way as a stabilization pattern was started. The experimental conditions of lysine acylation by the lipase B of Candida antarctica were determined using a model carotenoid, the bixin. The resulting product of the synthesis of bixin derivative was purified and showed an antiradical activity of 2.5 times higher than that of bixin. This result showed the ability of the acylation reaction of peptides with this kind of carotenoids
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8

Goujard, Laurent. "Synthèse de polyesters biodégradables par des lipases produites par des micro-organismes lipolytiques, isolés de feuilles à cuticule épaisse, et par une lipase immobilisée, le novozym 435." Aix-Marseille 3, 2009. http://www.theses.fr/2009AIX30046.

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L'objectif de cette thèse a été la synthèse par voie enzymatique de polyesters biodégradables à partir de ressources renouvelables provenant de productions d'oléagineux: le glycérol et le diacide oléique (D18 :1). Pour résoudre le problème économique lié au coût du biocatalyseur le plus efficace en polyestérification, la lipase immobilisée de Candida antarctica B (Novozym 435), de nouvelles lipases d'origine microbienne ont été recherchées dans des litières d'espèces végétales méditerranéennes. Dans ce but, a été développée une méthodologie permettant de mesurer le potentiel de synthèse d'enzymes lipolytiques, produites par des micro-organismes dégradant un polyester naturel, la cutine des feuilles. Une bactérie thermophile (BT2) a ainsi été sélectionnée parmi les souches isolées. Sa capacité à catalyser des polyestérifications a été évaluée et comparée à celle du Novozym 435. Ce dernier a été aussi utilisé pour mettre au point un système de synthèse en milieu fondu. Il a permis l'obtention d'un élastomère ayant un poids moléculaire supérieur à 134 kDa. Des mesures de biodégradabilité ont montré que ce polyester produit par voie enzymatique se minéralisé plus vite que des polyesters produits par chauffage à 160°C et 180°C. L'impact de la teneur en eau, du ratio molaire glycéroVacide, de la quantité d'enzyme dans le milieu réactionnel a été analysé
The aim of this thesis has been the enzymatic synthesis of biodegradable polyesters from renewable resources issued from oleaginous plants: glycerol and di-oleic acid. To work out the economical problem, due to the cost of the most efficacious bio-catalyser for polyesterification, the immobilised lipase of Candida antarctica B (Novozym 435), new microbial lipases has been researched in litters of Mediterranean plant species. With this object, a new methodology has been developed allowing to measure the potentialities of lipolytic enzymes to synthesise polyesters. These enzymes has been produced by micro-organisms able to degrade a natural polyester, the cutin. A thermophilic bacterium (BT2) has been selected among the isolated strains. Their capabilities to catalyse polyesterifications has been evaluated and compared to those of Novozym 435. This last bio-catalyser has also been used to study an apparatus to synthesise polyesters in bulk. In this conditions, an elastomer product was obtained with a molecular weight higher than 134 kDa. Biodegradability measures have shown that this polyester is faster mineralised than polyesters produced by heating from 160°C up to 180°C. The impact, of the a[w], molar ratio glycerol/acid and enzyme quantity in the reacting medium, on the yield and on the molecular weight of the polyesters formed has been studied
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9

Siqueira, Ana Karine Pessoa Bastos. "SÃntese de Derivados de Vitamina A utilizando Lipase de Candida antartica Imobilizada (Novozyme 435)." Universidade Federal do CearÃ, 2007. http://www.teses.ufc.br/tde_busca/arquivo.php?codArquivo=2311.

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O objetivo desta dissertaÃÃo foi sintetizar derivados de vitamina A por rota enzimÃtica, como alternativa à rota quÃmica, que à caracteristicamente mais agressiva ao meio ambiente. A sÃntese do palmitato de retinila resultaria em produto com melhor aceitaÃÃo de mercado, jà que à mais estÃvel do que o Ãster que foi utilizado como substrato, acetato de retinila. Jà a sÃntese de adipato de retinila, tinha como principal finalidade, disponibilizar um novo derivado de vitamina A. Para ambos, visava-se a aplicaÃÃo nas indÃstrias farmacÃutica, cosmÃtica e alimentÃcia. Nesse contexto, utilizou-se lipase de Candida antarctica tipo B imobilizada (Novozyme 435 com 571,48 UI/g  55,47) e os substratos acetato de retinila, Ãcidos palmÃtico e adÃpico. AlÃm destes, peneira molecular (PM) 3Ǻ tambÃm foi adicionada, jà que as reaÃÃes propostas liberam Ãgua para o meio reacional, desfavoredendo a sÃntese do Ãster desejado. Dois planejamentos foram realizados para se avaliar a sÃntese de palmitato de retinila, ambos em volume reacional total de 2 mL. No primeiro, trÃs variÃveis foram analisadas: proporÃÃo entre os substratos, solvente e temperatura. A quantidade de acetato de retinila foi mantida em 0,1 mmol e a do Ãcido palmÃtico variando entre 0,1 e 0,5 mmol. Levando em consideraÃÃo o coeficiente de partiÃÃo do Ãcido utilizado, foram testados tolueno e hexano. As temperaturas variaram entre 25 e 40ÂC, de acordo com o planejamento fatorial 23 blocado com ponto central. No segundo, estudou-se a influÃncia da quantidade de lipase (25, 50 e 75 mg) e PM (20, 50, 80 mg) em tolueno e hexano, conforme planejamento fatorial 32. Ensaios em maior escala foram realizados nÃo apenas para o palmitato, o qual foi submetido a teste de estabilidade tÃrmica, mas tambÃm para o adipato, que por nÃo ser comercializado precisou ser separado da reaÃÃo e identificado por ressonÃncia magnÃtica nuclear. Com uma anÃlise estatÃstica dos resultados, pÃde-se observar que os parÃmetros que tiveram efeito significativo no primeiro planejamento, foram a temperatura e a interaÃÃo desta com a razÃo molar entre os substratos. No segundo, tanto a enzima como a relaÃÃo quadrÃtica da PM foram significantes no rendimento de sÃntese com tolueno, e apenas a enzima, quando utilizado o hexano. A separaÃÃo do palmitato de retinila foi realizada em coluna de sÃlica C18, tendo sido avaliada em calorimetria exploratÃria diferencial (do inglÃs, differencial screening calorimetry - DSC) e observado eventos tÃrmicos por volta de 6,54ÂC. Quanto ao adipato de retinila, nenhum procedimento de separaÃÃo foi eficaz para a separaÃÃo da mistura formada entre o mesmo e o adipato de diretinila.
The main objective of this work was to synthesize vitamin A derivatives through an enzymatic route, as an alternative to chemistry route, more aggressive to the environment. The conversion of retinyl acetate into retinyl palmitate would result in a product with better market acceptance, since it is more stable than the ester used as substrate. Retinyl adipate synthesis, on the other hand, was studied in order to prepare a new vitamin A derivative. Both Vitamin A derivatives synthesized in this work were aiming the industrial production of cosmetics and foods. In this context, immobilized Candida antarctica type B lipase (Novozyme 435 with 571,48 UI/g  55,47) was used to catalyze the conversion of the substrates retinyl acetate, palmitic and adipic acids. In addition to these, molecular sieves was also added since the proposed reactions release water to the reaction media, which is not favorable to the desired ester synthesis. The retinyl palmitate synthesis was investigated by two factorial experimental design, using a total reactional volume of 2 mL. In the first, three variables were analyzed: rate between substrates, type of solvent and temperature. Retinyl acetate was kept in 0,1 mmol and palmitic acid varied between 0,1 and 0,5 mmol. Considering the acid partition coefficient, toluene and hexane were tested as solvents. The temperatures varied between 25 and 40ÂC, following a 23 factorial experimental design blocked with central points. In the second design, the influence of lipase (25, 50 e 75 mg) and molecular sieves (20, 50, 80 mg) amounts were studied using toluene or hexane as solvent, in accordance with a 32 factorial design. Experiments in a larger scale were performed not only to the produce retinyl palmitate, which was submitted to termic stability tests, but also to retinyl adipate, which is not commercially available and thereof it was recovered from the reactional media and identified by nuclear magnetic resonance. The statistical analysis of the results allowed the observation of significant effects. In the first planning, temperature and their interaction with the molar rate between the substrates were the significant variables. In the second, enzyme and the molecular sieves quadratic relation were significant in the yield of synthesis with toluene, but only the enzyme was significant when hexane was utilized. The retinyl palmitate separation was performed in silica C18 column and the purified sample was analyzed by differential scanning calorimetric â DS with a thermal event around 6.54ÂC. In the case of retinyl adipate, no separation procedure was effective since there is a mixture formed between retinyl and diretinyl adipates.
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10

Siqueira, Ana Karine Pessoa Bastos. "Síntese de derivados de vitamina A utilizando lipase de Candida antartica imobilizada (Novozyme 435)." reponame:Repositório Institucional da UFC, 2007. http://www.repositorio.ufc.br/handle/riufc/15768.

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SIQUEIRA, A. K. P. B. Síntese de derivados de vitamina A utilizando lipase de Candida antartica imobilizada (Novozyme 435). 93 f. 2007. Dissertação (Mestrado em Engenharia Química) – Centro de Tecnologia, Universidade Federal do Ceará, Fortaleza, 2007.
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The main objective of this work was to synthesize vitamin A derivatives through an enzymatic route, as an alternative to chemistry route, more aggressive to the environment. The conversion of retinyl acetate into retinyl palmitate would result in a product with better market acceptance, since it is more stable than the ester used as substrate. Retinyl adipate synthesis, on the other hand, was studied in order to prepare a new vitamin A derivative. Both Vitamin A derivatives synthesized in this work were aiming the industrial production of cosmetics and foods. In this context, immobilized Candida antarctica type B lipase (Novozyme 435 with 571,48 UI/g ± 55,47) was used to catalyze the conversion of the substrates retinyl acetate, palmitic and adipic acids. In addition to these, molecular sieves was also added since the proposed reactions release water to the reaction media, which is not favorable to the desired ester synthesis. The retinyl palmitate synthesis was investigated by two factorial experimental design, using a total reactional volume of 2 mL. In the first, three variables were analyzed: rate between substrates, type of solvent and temperature. Retinyl acetate was kept in 0,1 mmol and palmitic acid varied between 0,1 and 0,5 mmol. Considering the acid partition coefficient, toluene and hexane were tested as solvents. The temperatures varied between 25 and 40°C, following a 23 factorial experimental design blocked with central points. In the second design, the influence of lipase (25, 50 e 75 mg) and molecular sieves (20, 50, 80 mg) amounts were studied using toluene or hexane as solvent, in accordance with a 32 factorial design. Experiments in a larger scale were performed not only to the produce retinyl palmitate, which was submitted to termic stability tests, but also to retinyl adipate, which is not commercially available and thereof it was recovered from the reactional media and identified by nuclear magnetic resonance. The statistical analysis of the results allowed the observation of significant effects. In the first planning, temperature and their interaction with the molar rate between the substrates were the significant variables. In the second, enzyme and the molecular sieves quadratic relation were significant in the yield of synthesis with toluene, but only the enzyme was significant when hexane was utilized. The retinyl palmitate separation was performed in silica C18 column and the purified sample was analyzed by differential scanning calorimetric – DS with a thermal event around 6.54ºC. In the case of retinyl adipate, no separation procedure was effective since there is a mixture formed between retinyl and diretinyl adipates.
O objetivo desta dissertação foi sintetizar derivados de vitamina A por rota enzimática, como alternativa à rota química, que é caracteristicamente mais agressiva ao meio ambiente. A síntese do palmitato de retinila resultaria em produto com melhor aceitação de mercado, já que é mais estável do que o éster que foi utilizado como substrato, acetato de retinila. Já a síntese de adipato de retinila, tinha como principal finalidade, disponibilizar um novo derivado de vitamina A. Para ambos, visava-se a aplicação nas indústrias farmacêutica, cosmética e alimentícia. Nesse contexto, utilizou-se lipase de Candida antarctica tipo B imobilizada (Novozyme 435 com 571,48 UI/g ± 55,47) e os substratos acetato de retinila, ácidos palmítico e adípico. Além destes, peneira molecular (PM) 3Ǻ também foi adicionada, já que as reações propostas liberam água para o meio reacional, desfavoredendo a síntese do éster desejado. Dois planejamentos foram realizados para se avaliar a síntese de palmitato de retinila, ambos em volume reacional total de 2 mL. No primeiro, três variáveis foram analisadas: proporção entre os substratos, solvente e temperatura. A quantidade de acetato de retinila foi mantida em 0,1 mmol e a do ácido palmítico variando entre 0,1 e 0,5 mmol. Levando em consideração o coeficiente de partição do ácido utilizado, foram testados tolueno e hexano. As temperaturas variaram entre 25 e 40°C, de acordo com o planejamento fatorial 23 blocado com ponto central. No segundo, estudou-se a influência da quantidade de lipase (25, 50 e 75 mg) e PM (20, 50, 80 mg) em tolueno e hexano, conforme planejamento fatorial 32. Ensaios em maior escala foram realizados não apenas para o palmitato, o qual foi submetido a teste de estabilidade térmica, mas também para o adipato, que por não ser comercializado precisou ser separado da reação e identificado por ressonância magnética nuclear. Com uma análise estatística dos resultados, pôde-se observar que os parâmetros que tiveram efeito significativo no primeiro planejamento, foram a temperatura e a interação desta com a razão molar entre os substratos. No segundo, tanto a enzima como a relação quadrática da PM foram significantes no rendimento de síntese com tolueno, e apenas a enzima, quando utilizado o hexano. A separação do palmitato de retinila foi realizada em coluna de sílica C18, tendo sido avaliada em calorimetria exploratória diferencial (do inglês, differencial screening calorimetry - DSC) e observado eventos térmicos por volta de 6,54ºC. Quanto ao adipato de retinila, nenhum procedimento de separação foi eficaz para a separação da mistura formada entre o mesmo e o adipato de diretinila.
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Books on the topic "Novozym"

1

Malakhovskiĭ, Kim Vladimirovich. V Novom Alʹbione. Moskva: "Nauka," Glav. red. vostochnoĭ lit-ry, 1990.

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Khoruzhiĭ, S. S. O starom i novom. Sankt-Peterburg: Aleteĭi︠a︡, 2000.

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Pisʹmennyĭ, Boris. [Na novom meste: Rasskazy. Creskill, NJ: Otvet Right, Inc., 1998.

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O novom ustavu Srbije. Kraljevo: Doroteus, 2002.

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V novom veke: Stikhotvorenii︠a︡. Moskva: Progress-Plei︠a︡da, 2006.

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Blažević, Marin. Razgovori o novom kazalištu. Zagreb: Centar za Dramsku Umjetnost, 2007.

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Golon, Anne. Anzhelika v Novom Svete. Moskva: Izd-vo AST, 2001.

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Khoruzhiĭ, Sergeĭ Sergeevich. O starom i novom. Sankt Peterburg: Aleteĭi︠a︡, 2000.

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Blažević, Marin. Razgovori o novom kazalištu. Zagreb: Centar za Dramsku Umjetnost, 2007.

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Vuksanović, Slobodan. Priče o Novom Pazaru: Pripovetke studenata Državnog univerziteta u Novom Pazaru. Beograd: Šprint, 2013.

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Book chapters on the topic "Novozym"

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Calsavara, Luiza P. V., Flávio F. De Moraes, and Gisella M. Zanin. "Comparison of Catalytic Properties of Free and Immobilized Cellobiase Novozym 188." In Twenty-Second Symposium on Biotechnology for Fuels and Chemicals, 615–26. Totowa, NJ: Humana Press, 2001. http://dx.doi.org/10.1007/978-1-4612-0217-2_52.

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Palmans, Anja R. A., Bart A. C. van As, Jeroen van Buijtenen, and E. W. Meijer. "Ring-Opening of ω-Substituted Lactones by Novozym 435: Selectivity Issues and Application to Iterative Tandem Catalysis." In ACS Symposium Series, 230–44. Washington, DC: American Chemical Society, 2008. http://dx.doi.org/10.1021/bk-2008-0999.ch015.

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Emme, Brandon, and Alex Berlin. "Novozymes: How Novozymes Thinks About Biomass." In Industrial Biorenewables, 409–35. Hoboken, NJ, USA: John Wiley & Sons, Inc., 2016. http://dx.doi.org/10.1002/9781118843796.ch18.

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Mišev, Gordana, Petar Stanojević, and Zoran Jeftić. "Neki aspekti bezbednosti srpske infrastrukture na „Novom putu svile”." In Novi put svile: evropska perspektiva, 193–207. Beograd: Fakultet bezbednosti Univerziteta u Beogradu, 2018. http://dx.doi.org/10.18485/fb_nps.2018.ch12.

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Eames, J. "Using a Combination of Novozym 435 and a Ruthenium Complex." In Alcohols, 1. Georg Thieme Verlag KG, 2008. http://dx.doi.org/10.1055/sos-sd-036-00256.

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Azcar, Laura, Gustavo Ciudad, Robinson Muoz, David Jeison, Claudio Toro, and Rodrigo Navi. "Feasible Novozym 435-Catalyzed Process to Fatty Acid Methyl Ester Production from Waste Frying Oil: Role of Lipase Inhibition." In Enzyme Inhibition and Bioapplications. InTech, 2012. http://dx.doi.org/10.5772/34758.

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Lovelock, James, and Bryan Appleyard. "TEIL EINS." In Novozän, 15–48. Verlag C.H.BECK oHG, 2020. http://dx.doi.org/10.17104/9783406745706-15.

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Lovelock, James, and Bryan Appleyard. "Zum Geleit." In Novozän, 151–58. Verlag C.H.BECK oHG, 2020. http://dx.doi.org/10.17104/9783406745706-151.

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Lovelock, James, and Bryan Appleyard. "Dank." In Novozän, 159. Verlag C.H.BECK oHG, 2020. http://dx.doi.org/10.17104/9783406745706-159.

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Lovelock, James, and Bryan Appleyard. "Autorentext." In Novozän, 160. Verlag C.H.BECK oHG, 2020. http://dx.doi.org/10.17104/9783406745706-160.

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Conference papers on the topic "Novozym"

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SANTIN, C. M. T., D. de OLIVEIRA, J. V. de OLIVEIRA, and C. DALLA ROSA. "ESTUDO DAS LIPASES LIPOZYME RM IM, LIPOZYME TL IM E NOVOZYM 435 PARA A PRODUÇÃO DE BIODIESEL." In XX Congresso Brasileiro de Engenharia Química. São Paulo: Editora Edgard Blücher, 2015. http://dx.doi.org/10.5151/chemeng-cobeq2014-1019-21569-144311.

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FIDALGO, W. R. R., L. F. TEIXEIRA, J. C. SANTOS, and H. F. de CASTRO. "ESTABELECIMENTO DAS CONDIÇÕES OPERACIONAIS PARA A SÍNTESE DE BIODIESEL CATALISADA POR NOVOZYM® 435 EM REATOR DE LEITO FLUIDIZADO." In XX Congresso Brasileiro de Engenharia Química. São Paulo: Editora Edgard Blücher, 2015. http://dx.doi.org/10.5151/chemeng-cobeq2014-1551-18707-155999.

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Gabrik, Peter. "Inštitút vydržania vlastníctva nehnuteľností po novom." In Právne rozpravy on-screen II. Belianum. Vydavateľstvo Univerzity Mateja Bela v Banskej Bystrici, 2021. http://dx.doi.org/10.24040/pros.13.11.2020.ssp.34-42.

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Akchurina, A. R. "The newspaper Novoye Vremya about the 1913 Mendel Beilis case." In 6th Conference "Advanced Studies in Science: Theory and Practice". Global Partnership on Development of Scientific Cooperation LLC., 2015. http://dx.doi.org/10.17809/25(2015)-07.

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Zakić, Marko. "Menadžment u novom poslovnom okruženju – izazovi digitalne ekonomije." In Sinteza 2014. Belgrade, Serbia: Singidunum University, 2014. http://dx.doi.org/10.15308/sinteza-2014-116-120.

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Larsen, M. H., M. K. Pedersen, and K. Viborg Andersen. "IT Governance: Reviewing 17 IT Governance Tools and Analysing the Case of Novozymes A/S." In Proceedings of the 39th Annual Hawaii International Conference on System Sciences (HICSS'06). IEEE, 2006. http://dx.doi.org/10.1109/hicss.2006.234.

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Kliček, Tamara, and Tatjana Vanić. "KONCEPT KREATIVNOG GRADA U FUNKCIJI UNAPREĐENJA RAZVOJA HOTELIJERSTVA U NOVOM SADU." In Sitcon 2015. Belgrade, Serbia: Singidunum University, 2015. http://dx.doi.org/10.15308/sitcon-2015-155-160.

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Jovanović, Irena. "Istraživanje stavova lokalnog stanovništva u funkciji održivog razvoja turizma u Herceg Novom." In Synthesis 2015. Belgrade, Serbia: Singidunum University, 2015. http://dx.doi.org/10.15308/synthesis-2015-558-560.

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Mićanović, Krešimir. "„Jedan narodni jezik i jedan jedinstven književni jezik“. Anketa Letopisa matice srpske i sastanak u Novom Sadu." In Desničini susreti 2018. Filozofski fakultet u Zagrebu, FF Press, 2019. http://dx.doi.org/10.17234/desnicini_susreti2018.10.

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Djokic, Jasmina. "NAKNADA ŠTETE USLIJED PRETRPLjENIH TJELESNIH POVREDA I SMRTI PREMA NOVOM ZAKONU O OBAVEZNOM OSIGURANjU U SAOBRAĆAJU FEDERACIJE BOSNE I HERCEGOVINE." In MODERNE TEHNOLOGIJE, NOVI I TRADICIONALNI RIZICI U OSIGURANjU. Association for Insurance Law of Serbia, 2021. http://dx.doi.org/10.46793/xxsav21.071dj.

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Abstract:
Th e new Law on Compulsory Traffi c Insurance has recently entered into force in the Federation of Bosnia and Herzegovina. By enacting of this Law the high level of harmonization with EU-acquis has been achieved. Besides, the interstate harmonization, i.e. equalization with the same-named Law act in Republic of Srpska has also been achieved. Th e special characteristic of this Law that diff ers it from the similar acts in SEE region and wider, is regulating of the rules for determination of the scope of pecuniary and non-pecuniary damage occurred in a traffi c accident. Th e set of rules is prescribed in form of the Framework criteria for determining the compensation amount for injuries or death, which are an integral part of the Law. In this paperwork, the overview of the mentioned Framework criteria will be shown, as well as their importance with regards of legal certainty in determination of the scope of damage. Also, there is a discussion about overcoming the interstate confl ict of law that occurred by their enacting.
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