Log in

Relevant bibliographies by topics / Npl3 / Journal articles

To see the other types of publications on this topic, follow the link: Npl3.

Journal articles on the topic 'Npl3'

Author: Grafiati

Published: 9 March 2023

Last updated: 31 July 2025

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the top 50 journal articles for your research on the topic 'Npl3.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Browse journal articles on a wide variety of disciplines and organise your bibliography correctly.

1

Henry, Michael, Christina Z. Borland, Mark Bossie, and Pamela A. Silver. "Potential RNA Binding Proteins in Saccharomyces cerevisiae Identified as Suppressors of Temperature-Sensitive Mutations in NPL3." Genetics 142, no. 1 (1996): 103–15. http://dx.doi.org/10.1093/genetics/142.1.103.

Full text

Abstract:

The NPL3 gene of the yeast Saccharomyces cerevisiae encodes a protein with similarity to heterogeneous nuclear ribonucleoproteins (hnRNPs). Npl3p has been implicated in many nuclear-related events including RNA export, protein import, and rRNA processing. Several temperature-sensitive alleles of NPL3 have been isolated. We now report the sequence of these alleles. For one allele, npl3-1, four complementation groups of suppressors have been isolated. The cognate genes for the two recessive mutants were cloned. One of these is the previously known RNA15, which, like NPL3, also encodes a protein

APA, Harvard, Vancouver, ISO, and other styles

2

Nelson, M. K., T. Kurihara, and P. A. Silver. "Extragenic suppressors of mutations in the cytoplasmic C terminus of SEC63 define five genes in Saccharomyces cerevisiae." Genetics 134, no. 1 (1993): 159–73. http://dx.doi.org/10.1093/genetics/134.1.159.

Full text

Abstract:

Abstract Mutations in the SEC63 gene of Saccharomyces cerevisiae affect both nuclear protein localization and translocation of proteins into the endoplasmic reticulum. We now report the isolation of suppressors of sec63-101 (formerly npl1-1), a temperature-sensitive allele of SEC63. Five complementation groups of extragenic mutations, son1-son5 (suppressor of npl1-1), were identified among the recessive suppressors. The son mutations are specific to SEC63, are not bypass suppressors, and are not new alleles of previously identified secretory (SEC61, SEC62, KAR2) or nuclear protein localization

APA, Harvard, Vancouver, ISO, and other styles

3

Henry, M. F., and P. A. Silver. "A novel methyltransferase (Hmt1p) modifies poly(A)+-RNA-binding proteins." Molecular and Cellular Biology 16, no. 7 (1996): 3668–78. http://dx.doi.org/10.1128/mcb.16.7.3668.

Full text

Abstract:

RNA-binding proteins play many essential roles in the metabolism of nuclear pre-mRNA. As such, they demonstrate a myriad of dynamic behaviors and modifications. In particular, heterogeneous nuclear ribonucleoproteins (hnRNPs) contain the bulk of methylated arginine residues in eukaryotic cells. We have identified the first eukaryotic hnRNP-specific methyltransferase via a genetic screen for proteins that interact with an abundant poly(A)+-RNA-binding protein termed Npl3p. We have previously shown that npl3-1 mutants are temperature sensitive for growth and defective for export of mRNA from the

APA, Harvard, Vancouver, ISO, and other styles

4

Lund, Mette K., Tracy L. Kress, and Christine Guthrie. "Autoregulation of Npl3, a Yeast SR Protein, Requires a Novel Downstream Region and Serine Phosphorylation." Molecular and Cellular Biology 28, no. 11 (2008): 3873–81. http://dx.doi.org/10.1128/mcb.02153-07.

Full text

Abstract:

ABSTRACT Npl3 is an SR-like protein with documented roles in mRNA export and transcription termination. Maintaining appropriate levels of Npl3 protein is critical for cell survival. Here we show that Npl3 negatively regulates its own expression via modulation of its mRNA levels. By creating gene chimeras, we demonstrate that the region downstream of the coding sequence of Npl3 is necessary and sufficient to confer regulation. The use of different polyadenylation sites in this region results in at least two stable RNAs; read-through of these sites causes the formation of 3′-extended RNAs that a

APA, Harvard, Vancouver, ISO, and other styles

5

Loo, S., P. Laurenson, M. Foss, A. Dillin, and J. Rine. "Roles of ABF1, NPL3, and YCL54 in silencing in Saccharomyces cerevisiae." Genetics 141, no. 3 (1995): 889–902. http://dx.doi.org/10.1093/genetics/141.3.889.

Full text

Abstract:

Abstract A sensitized genetic screen was carried out to identify essential genes involved in silencing in Saccharomyces cerevisiae. This screen identified temperature-sensitive alleles of ORC2 and ORC5, as described elsewhere, and ABF1, NPL3, and YCL54, as described here. Alleles of ABF1 that caused silencing defects provided the genetic proof of Abflp's role in silencing. The roles of Npl3p and Ycl54p are less clear. These proteins did not act exclusively through any one of the three protein binding sites of the HMR-E silencer. Unlike the orc2, orc5, and abf1 mutations that were isolated in t

APA, Harvard, Vancouver, ISO, and other styles

6

Sandhu, Rima, Aniketa Sinha, and Ben Montpetit. "The SR-protein Npl3 is an essential component of the meiotic splicing regulatory network in Saccharomyces cerevisiae." Nucleic Acids Research 49, no. 5 (2021): 2552–68. http://dx.doi.org/10.1093/nar/gkab071.

Full text

Abstract:

Abstract The meiotic gene expression program in Saccharomyces cerevisiae involves regulated splicing of meiosis-specific genes via multiple splicing activators (e.g. Mer1, Nam8, Tgs1). Here, we show that the SR protein Npl3 is required for meiotic splicing regulation and is essential for proper execution of the meiotic cell cycle. The loss of Npl3, though not required for viability in mitosis, caused intron retention in meiosis-specific transcripts, inefficient meiotic double strand break processing and an arrest of the meiotic cell cycle. The targets of Npl3 overlapped in some cases with othe

APA, Harvard, Vancouver, ISO, and other styles

7

Bossie, M. A., C. DeHoratius, G. Barcelo, and P. Silver. "A mutant nuclear protein with similarity to RNA binding proteins interferes with nuclear import in yeast." Molecular Biology of the Cell 3, no. 8 (1992): 875–93. http://dx.doi.org/10.1091/mbc.3.8.875.

Full text

Abstract:

We have isolated mutants of the yeast Saccharomyces cerevisiae that are defective in localization of nuclear proteins. Chimeric proteins containing the nuclear localization sequence from SV40 large T-antigen fused to the N-terminus of the mitochondrial F1 beta-ATPase are localized to the nucleus. Npl (nuclear protein localization) mutants were isolated by their ability to grow on glycerol as a consequence of no longer exclusively targeting SV40-F1 beta-ATPase to the nucleus. All mutants with defects in localization of nucleolar proteins and histones are temperature sensitive for growth at 36 d

APA, Harvard, Vancouver, ISO, and other styles

8

Flach, J., M. Bossie, J. Vogel, et al. "A yeast RNA-binding protein shuttles between the nucleus and the cytoplasm." Molecular and Cellular Biology 14, no. 12 (1994): 8399–407. http://dx.doi.org/10.1128/mcb.14.12.8399-8407.1994.

Full text

Abstract:

RNA-binding proteins have been suggested to move in association with RNA as it leaves the nucleus. The NPL3 gene of the yeast Saccharomyces cerevisiae encodes in nuclear protein with consensus RNA-binding motifs and similarity to heterogeneous nuclear ribonucleoproteins and members of the S/R protein family. We show that although Npl3 is located in the nucleus, it can shuttle between nuclei in yeast heterokaryons. In contrast, other nucleus-targeted proteins do not leave the nucleus under similar conditions. Mutants missing the RNA-binding motifs or the N terminus are still capable of shuttlin

APA, Harvard, Vancouver, ISO, and other styles

9

Flach, J., M. Bossie, J. Vogel, et al. "A yeast RNA-binding protein shuttles between the nucleus and the cytoplasm." Molecular and Cellular Biology 14, no. 12 (1994): 8399–407. http://dx.doi.org/10.1128/mcb.14.12.8399.

Full text

Abstract:

RNA-binding proteins have been suggested to move in association with RNA as it leaves the nucleus. The NPL3 gene of the yeast Saccharomyces cerevisiae encodes in nuclear protein with consensus RNA-binding motifs and similarity to heterogeneous nuclear ribonucleoproteins and members of the S/R protein family. We show that although Npl3 is located in the nucleus, it can shuttle between nuclei in yeast heterokaryons. In contrast, other nucleus-targeted proteins do not leave the nucleus under similar conditions. Mutants missing the RNA-binding motifs or the N terminus are still capable of shuttlin

APA, Harvard, Vancouver, ISO, and other styles

10

Singleton, D. R., S. Chen, M. Hitomi, C. Kumagai, and A. M. Tartakoff. "A yeast protein that bidirectionally affects nucleocytoplasmic transport." Journal of Cell Science 108, no. 1 (1995): 265–72. http://dx.doi.org/10.1242/jcs.108.1.265.

Full text

Abstract:

We have identified a temperature-sensitive mutant of Saccharomyces cerevisiae (npl3) that accumulates polyadenylated RNA in the nucleus at 37 degrees C, as judged by in situ hybridization. The strong nuclear signal is not simply due to increased cytoplasmic turnover of mRNA, as reincubation at 37 degrees C with an RNA polymerase inhibitor shows no diminution in the in situ signal. Over several hours at 37 degrees C, the average poly(A) tail length increases and a characteristic ultrastructural alteration of the nucleoplasm occurs. Cloning and sequencing indicate that the corresponding gene is

APA, Harvard, Vancouver, ISO, and other styles

11

Rollenhagen, Christiane, Christine A. Hodge, and Charles N. Cole. "Following Temperature Stress, Export of Heat Shock mRNA Occurs Efficiently in Cells with Mutations in Genes Normally Important for mRNA Export." Eukaryotic Cell 6, no. 3 (2007): 505–13. http://dx.doi.org/10.1128/ec.00317-06.

Full text

Abstract:

ABSTRACT Heat shock leads to accumulation of polyadenylated RNA in nuclei of Saccharomyces cerevisiae cells, transcriptional induction of heat shock genes, and efficient export of polyadenylated heat shock mRNAs. These studies were conducted to examine the requirements for export of mRNA following heat shock. We used in situ hybridization to detect SSA4 mRNA (encoding Hsp70) and flow cytometry to measure the amount of Ssa4p-green fluorescent protein (GFP) produced following heat shock. Npl3p and Yra1p are mRNA-binding proteins recruited to nascent mRNAs and are essential for proper mRNA biogen

APA, Harvard, Vancouver, ISO, and other styles

12

McBride, Anne E., Cecilia Zurita-Lopez, Anthony Regis, et al. "Protein Arginine Methylation in Candida albicans: Role in Nuclear Transport." Eukaryotic Cell 6, no. 7 (2007): 1119–29. http://dx.doi.org/10.1128/ec.00074-07.

Full text

Abstract:

ABSTRACT Protein arginine methylation plays a key role in numerous eukaryotic processes, such as protein transport and signal transduction. In Candida albicans, two candidate protein arginine methyltransferases (PRMTs) have been identified from the genome sequencing project. Based on sequence comparison, C. albicans candidate PRMTs display similarity to Saccharomyces cerevisiae Hmt1 and Rmt2. Here we demonstrate functional homology of Hmt1 between C. albicans and S. cerevisiae: CaHmt1 supports growth of S. cerevisiae strains that require Hmt1, and CaHmt1 methylates Npl3, a major Hmt1 substrate

APA, Harvard, Vancouver, ISO, and other styles

13

Windgassen, Merle, Dorothée Sturm, Iván J. Cajigas, et al. "Yeast Shuttling SR Proteins Npl3p, Gbp2p, and Hrb1p Are Part of the Translating mRNPs, and Npl3p Can Function as a Translational Repressor." Molecular and Cellular Biology 24, no. 23 (2004): 10479–91. http://dx.doi.org/10.1128/mcb.24.23.10479-10491.2004.

Full text

Abstract:

ABSTRACT A major challenge in current molecular biology is to understand how sequential steps in gene expression are coupled. Recently, much attention has been focused on the linkage of transcription, processing, and mRNA export. Here we describe the cytoplasmic rearrangement for shuttling mRNA binding proteins in Saccharomyces cerevisiae during translation. While the bulk of Hrp1p, Nab2p, or Mex67p is not associated with polysome containing mRNAs, significant amounts of the serine/arginine (SR)-type shuttling mRNA binding proteins Npl3p, Gbp2p, and Hrb1p remain associated with the mRNA-protei

APA, Harvard, Vancouver, ISO, and other styles

14

Xu, Chong, and Michael F. Henry. "Nuclear Export of hnRNP Hrp1p and Nuclear Export of hnRNP Npl3p Are Linked and Influenced by the Methylation State of Npl3p." Molecular and Cellular Biology 24, no. 24 (2004): 10742–56. http://dx.doi.org/10.1128/mcb.24.24.10742-10756.2004.

Full text

Abstract:

ABSTRACT Eukaryotic mRNA processing and export are mediated by a series of complexes composed of heterogeneous nuclear ribonucleoproteins (hnRNPs). Many of these hnRNPs are methylated at arginine residues within their RGG domains. Although cellular arginine methylation is required for the efficient nuclear export of several hnRNPs, its role in this process is unknown. To address this question, we replaced the methylated RGG tripeptides of two hnRNPs, Npl3p and Hrp1p, with KGG. We found that these substitutions specifically abolish their methylation but have different effects on their nuclear e

APA, Harvard, Vancouver, ISO, and other styles

15

BADENE, Abdelkader, та Boulerbah BOUKHARI. "جودة الأصول بالقطاع المصرفي الجزائري بين البنوك العمومية والبنوك الخاصة للفترة (2014-2022)". Dirassat Journal Economic Issue 15, № 2 (2024): 1–19. http://dx.doi.org/10.34118/djei.v15i2.3931.

Full text

Abstract:

هدف الدراسة هو تحليل ودراسة مؤشرات جودة الأصول بالقطاع المصرفي الجزائري من خلال المقارنة بين البنوك العمومية والبنوك الخاصة خلال فترة 2014-2022، تم تجميع البيانات من تقارير بنك الجزائر. مع اعتماد ثلاث مؤشرات لجودة الأصول (نسبة القروض المتعثرة الصافية من المؤونات إلى رأس المال الخاص القانوني NPL1 ونسبة القروض المتعثرة NPL2) حسب دليل مؤشرات السلامة المالية لصندوق النقد الدولي، ومؤشر (نسبة مؤونات القروض المتعثرة NPLP) الذي يتعامل به بنك الجزائر، تم استخدام أساليب الإحصاء الوصفي لتحديد المتوسط الحسابي، أعلى وأدنى قيمة للمؤشرات، وأساليب الإحصاء الاستدلالي (اختبارt) لتحديد الفروق بين متوسط مؤشرات جو

APA, Harvard, Vancouver, ISO, and other styles

16

Wong, Chi-Ming, Hongfang Qiu, Cuihua Hu, Jinsheng Dong, and Alan G. Hinnebusch. "Yeast Cap Binding Complex Impedes Recruitment of Cleavage Factor IA to Weak Termination Sites." Molecular and Cellular Biology 27, no. 18 (2007): 6520–31. http://dx.doi.org/10.1128/mcb.00733-07.

Full text

Abstract:

ABSTRACT Nuclear cap binding complex (CBC) is recruited cotranscriptionally and stimulates spliceosome assembly on nascent mRNAs; however, its possible functions in regulating transcription elongation or termination were not well understood. We show that, while CBC appears to be dispensable for normal rates and processivity of elongation by RNA polymerase II (Pol II), it plays a direct role in preventing polyadenylation at weak termination sites. Similarly to Npl3p, with which it interacts, CBC suppresses the weak terminator of the gal10-Δ56 mutant allele by impeding recruitment of termination

APA, Harvard, Vancouver, ISO, and other styles

17

Dermody, Jessica L., Jonathan M. Dreyfuss, Judit Villén, et al. "Unphosphorylated SR-Like Protein Npl3 Stimulates RNA Polymerase II Elongation." PLoS ONE 3, no. 9 (2008): e3273. http://dx.doi.org/10.1371/journal.pone.0003273.

Full text

APA, Harvard, Vancouver, ISO, and other styles

18

Estrella, Luis A., Miles F. Wilkinson, and Carlos I. González. "The Shuttling Protein Npl3 Promotes Translation Termination Accuracy in Saccharomyces cerevisiae." Journal of Molecular Biology 394, no. 3 (2009): 410–22. http://dx.doi.org/10.1016/j.jmb.2009.08.067.

Full text

APA, Harvard, Vancouver, ISO, and other styles

19

Metur, Shree Padma, Xinxin Song, Sophie Mehta, et al. "Yeast TIA1 coordinates with Npl3 to promote ATG1 translation during starvation." Cell Reports 44, no. 2 (2025): 115316. https://doi.org/10.1016/j.celrep.2025.115316.

Full text

APA, Harvard, Vancouver, ISO, and other styles

20

Metur, Shree Padma, Xinxin Song, Sophie Mehta, et al. "Yeast TIA1 coordinates with Npl3 to promote ATG1 translation during starvation." Cell Reports 44, no. 6 (2025): 115847. https://doi.org/10.1016/j.celrep.2025.115847.

Full text

APA, Harvard, Vancouver, ISO, and other styles

21

Moehle, Erica A., Colm J. Ryan, Nevan J. Krogan, Tracy L. Kress, and Christine Guthrie. "The Yeast SR-Like Protein Npl3 Links Chromatin Modification to mRNA Processing." PLoS Genetics 8, no. 11 (2012): e1003101. http://dx.doi.org/10.1371/journal.pgen.1003101.

Full text

APA, Harvard, Vancouver, ISO, and other styles

22

Aubol, Brandon E., Leslie Ungs, Randy Lukasiewicz, Gourisankar Ghosh, and Joseph A. Adams. "Chemical Clamping Allows for Efficient Phosphorylation of the RNA Carrier Protein Npl3." Journal of Biological Chemistry 279, no. 29 (2004): 30182–88. http://dx.doi.org/10.1074/jbc.m402797200.

Full text

APA, Harvard, Vancouver, ISO, and other styles

23

Baierlein, C., A. Hackmann, T. Gross, L. Henker, F. Hinz, and H. Krebber. "Monosome Formation during Translation Initiation Requires the Serine/Arginine-Rich Protein Npl3." Molecular and Cellular Biology 33, no. 24 (2013): 4811–23. http://dx.doi.org/10.1128/mcb.00873-13.

Full text

APA, Harvard, Vancouver, ISO, and other styles

24

Santos-Pereira, J. M., A. B. Herrero, M. L. Garcia-Rubio, A. Marin, S. Moreno, and A. Aguilera. "The Npl3 hnRNP prevents R-loop-mediated transcription-replication conflicts and genome instability." Genes & Development 27, no. 22 (2013): 2445–58. http://dx.doi.org/10.1101/gad.229880.113.

Full text

APA, Harvard, Vancouver, ISO, and other styles

25

Hackmann, Alexandra, Thomas Gross, Claudia Baierlein, and Heike Krebber. "The mRNA export factor Npl3 mediates the nuclear export of large ribosomal subunits." EMBO reports 12, no. 10 (2011): 1024–31. http://dx.doi.org/10.1038/embor.2011.155.

Full text

APA, Harvard, Vancouver, ISO, and other styles

26

Kress, Tracy L., Nevan J. Krogan, and Christine Guthrie. "A Single SR-like Protein, Npl3, Promotes Pre-mRNA Splicing in Budding Yeast." Molecular Cell 32, no. 5 (2008): 727–34. http://dx.doi.org/10.1016/j.molcel.2008.11.013.

Full text

APA, Harvard, Vancouver, ISO, and other styles

27

Bucheli, Miriam E., and Stephen Buratowski. "Npl3 is an antagonist of mRNA 3′ end formation by RNA polymerase II." EMBO Journal 24, no. 12 (2005): 2150–60. http://dx.doi.org/10.1038/sj.emboj.7600687.

Full text

APA, Harvard, Vancouver, ISO, and other styles

28

Querl, Luisa, and Heike Krebber. "Defenders of the Transcriptome: Guard Protein-Mediated mRNA Quality Control in Saccharomyces cerevisiae." International Journal of Molecular Sciences 25, no. 19 (2024): 10241. http://dx.doi.org/10.3390/ijms251910241.

Full text

Abstract:

Cell survival depends on precise gene expression, which is controlled sequentially. The guard proteins surveil mRNAs from their synthesis in the nucleus to their translation in the cytoplasm. Although the proteins within this group share many similarities, they play distinct roles in controlling nuclear mRNA maturation and cytoplasmic translation by supporting the degradation of faulty transcripts. Notably, this group is continuously expanding, currently including the RNA-binding proteins Npl3, Gbp2, Hrb1, Hrp1, and Nab2 in Saccharomyces cerevisiae. Some of the human serine–arginine (SR) splic

APA, Harvard, Vancouver, ISO, and other styles

29

Santos-Pereira, José M., Ana B. Herrero, Sergio Moreno, and Andrés Aguilera. "Npl3, a new link between RNA-binding proteins and the maintenance of genome integrity." Cell Cycle 13, no. 10 (2014): 1524–29. http://dx.doi.org/10.4161/cc.28708.

Full text

APA, Harvard, Vancouver, ISO, and other styles

30

Holmes, Rebecca K., Alex C. Tuck, Chenchen Zhu, et al. "Loss of the Yeast SR Protein Npl3 Alters Gene Expression Due to Transcription Readthrough." PLOS Genetics 11, no. 12 (2015): e1005735. http://dx.doi.org/10.1371/journal.pgen.1005735.

Full text

APA, Harvard, Vancouver, ISO, and other styles

31

Gupta, Adity, Ashutosh Kumar, Neha Singh, et al. "The Saccharomyces cerevisiae SR protein Npl3 interacts with hyperphosphorylated CTD of RNA Polymerase II." International Journal of Biological Macromolecules 253 (December 2023): 127541. http://dx.doi.org/10.1016/j.ijbiomac.2023.127541.

Full text

APA, Harvard, Vancouver, ISO, and other styles

32

Bucheli, M. E., X. He, C. D. Kaplan, C. L. Moore, and S. Buratowski. "Polyadenylation site choice in yeast is affected by competition between Npl3 and polyadenylation factor CFI." RNA 13, no. 10 (2007): 1756–64. http://dx.doi.org/10.1261/rna.607207.

Full text

APA, Harvard, Vancouver, ISO, and other styles

33

Deka, Pritilekha, Miriam E. Bucheli, Claire Moore, Stephen Buratowski, and Gabriele Varani. "Structure of the Yeast SR Protein Npl3 and Interaction with mRNA 3′-End Processing Signals." Journal of Molecular Biology 375, no. 1 (2008): 136–50. http://dx.doi.org/10.1016/j.jmb.2007.09.029.

Full text

APA, Harvard, Vancouver, ISO, and other styles

34

Colombo, Chiara Vittoria, Camilla Trovesi, Luca Menin, Maria Pia Longhese, and Michela Clerici. "The RNA binding protein Npl3 promotes resection of DNA double-strand breaks by regulating the levels of Exo1." Nucleic Acids Research 45, no. 11 (2017): 6530–45. http://dx.doi.org/10.1093/nar/gkx347.

Full text

APA, Harvard, Vancouver, ISO, and other styles

35

McBride, Anne E., Jeffrey T. Cook, Elizabeth A. Stemmler, Kate L. Rutledge, Kelly A. McGrath, and Jeffrey A. Rubens. "Arginine Methylation of Yeast mRNA-binding Protein Npl3 Directly Affects Its Function, Nuclear Export, and Intranuclear Protein Interactions." Journal of Biological Chemistry 280, no. 35 (2005): 30888–98. http://dx.doi.org/10.1074/jbc.m505831200.

Full text

APA, Harvard, Vancouver, ISO, and other styles

36

Benedicta OWONYE and Godwin OBONOFIEMRO. "DETERMINANTS OF NON-PERFORMING LOANS IN THE NIGERIA BANKING INDUSTRY." International Journal of Management & Entrepreneurship Research 4, no. 11 (2022): 428–40. http://dx.doi.org/10.51594/ijmer.v4i11.402.

Full text

Abstract:

This study examined the determinants of non-performing loans (NPLs) in the Nigeria banking industry between the periods of 2011-2020. The specific objective of the study is to examine the relationship between the measures of bank specific variables [Bank Size (BS), Capital Adequacy (CA), Profitability (PROF), Bank Age (BA), Liquidity (LIQ) and Loan to Total Assets (LTA)] and [NPLs proxy with Non Performing Loans Ratio (NPLR)] in Nigeria. The focus on the banks in Nigeria listed in the Nigeria Stock Exchange and the difficulty in assessing their annual reports and account of 10 banks were drawn

APA, Harvard, Vancouver, ISO, and other styles

37

Muddukrishna, Bhavana, Christopher A. Jackson, and Michael C. Yu. "Protein arginine methylation of Npl3 promotes splicing of the SUS1 intron harboring non-consensus 5′ splice site and branch site." Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms 1860, no. 6 (2017): 730–39. http://dx.doi.org/10.1016/j.bbagrm.2017.04.001.

Full text

APA, Harvard, Vancouver, ISO, and other styles

38

Stochaj, U., M. A. Bossie, K. van Zee, A. M. Whalen, and P. A. Silver. "Analysis of conserved binding proteins for nuclear localization sequences." Journal of Cell Science 104, no. 1 (1993): 89–95. http://dx.doi.org/10.1242/jcs.104.1.89.

Full text

Abstract:

Correct targeting of nuclear proteins is mediated by nuclear localization sequences (NLS) which permit specific binding to the nucleus and subsequent translocation across the nuclear envelope via the nuclear pore complex. It is proposed that nuclear import is facilitated by NLS-receptors which reside in the cytoplasm and at the nuclear pore. These NLS-receptors could facilitate an early step of nuclear protein import, i.e. targeting and binding of nuclear proteins at the nuclear pore. We have generated anti-idiotype antibodies against the SV40 T-antigen nuclear localization sequence that allow

APA, Harvard, Vancouver, ISO, and other styles

39

Chen, Yin-Chu, Eric J. Milliman, Isabelle Goulet, et al. "Protein Arginine Methylation Facilitates Cotranscriptional Recruitment of Pre-mRNA Splicing Factors." Molecular and Cellular Biology 30, no. 21 (2010): 5245–56. http://dx.doi.org/10.1128/mcb.00359-10.

Full text

Abstract:

ABSTRACT Cotranscriptional recruitment of pre-mRNA splicing factors to their genomic targets facilitates efficient and ordered assembly of a mature messenger ribonucleoprotein particle (mRNP). However, how the cotranscriptional recruitment of splicing factors is regulated remains largely unknown. Here, we demonstrate that protein arginine methylation plays a novel role in regulating this process in Saccharomyces cerevisiae. Our data show that Hmt1, the major type I arginine methyltransferase, methylates Snp1, a U1 small nuclear RNP (snRNP)-specific protein, and that the mammalian Snp1 homolog,

APA, Harvard, Vancouver, ISO, and other styles

40

Ariyachet, Chaiyaboot, Norma V. Solis, Yaoping Liu, Nemani V. Prasadarao, Scott G. Filler, and Anne E. McBride. "SR-Like RNA-Binding Protein Slr1 Affects Candida albicans Filamentation and Virulence." Infection and Immunity 81, no. 4 (2013): 1267–76. http://dx.doi.org/10.1128/iai.00864-12.

Full text

Abstract:

ABSTRACTCandida albicanscauses both mucosal and disseminated infections, and its capacity to grow as both yeast and hyphae is a key virulence factor. Hyphal formation is a type of polarized growth, and members of the SR (serine-arginine) family of RNA-binding proteins influence polarized growth of bothSaccharomyces cerevisiaeandAspergillus nidulans. Therefore, we investigated whether SR-like proteins affect filamentous growth and virulence ofC. albicans. BLAST searches withS. cerevisiaeSR-like protein Npl3 (ScNpl3) identified twoC. albicansproteins: CaNpl3, an apparent ScNpl3 ortholog, and Slr

APA, Harvard, Vancouver, ISO, and other styles

41

Smith, Daniela-Lee, Michael Götze, Tara K. Bartolec, Gene Hart-Smith, and Marc R. Wilkins. "Characterization of the Interaction between Arginine Methyltransferase Hmt1 and Its Substrate Npl3: Use of Multiple Cross-Linkers, Mass Spectrometric Approaches, and Software Platforms." Analytical Chemistry 90, no. 15 (2018): 9101–8. http://dx.doi.org/10.1021/acs.analchem.8b01525.

Full text

APA, Harvard, Vancouver, ISO, and other styles

42

Zheng, Wenwen, Wei Jiang, Qingna Wu, et al. "Comparisons of different lymph node staging systems for predicting overall survival of node-positive patients with renal cell carcinoma: a retrospective cohort study using the Surveillance, Epidemiology and End Results database." BMJ Open 13, no. 4 (2023): e068044. http://dx.doi.org/10.1136/bmjopen-2022-068044.

Full text

Abstract:

ObjectivesTo compare the prognostic values of three lymph node staging systems in renal cell carcinoma (RCC), including the number of positive lymph nodes (NPLN), lymph node ratio (LNR) and log odds of positive lymph nodes (LODDS).DesignA retrospective cohort study using data from the Surveillance, Epidemiology and End Results (SEER) database.Setting and participants1904 patients with pathological N1 RCC, diagnosed from 2004 to 2015 and underwent nephrectomy combined with lymph node dissection, were identified from the SEER database.Primary outcome measureThe primary outcome of this study was

APA, Harvard, Vancouver, ISO, and other styles

43

Markovich, Sarit, Aya Yekutiel, Itamar Shalit, Yona Shadkchan, and Nir Osherov. "Genomic Approach to Identification of Mutations Affecting Caspofungin Susceptibility in Saccharomyces cerevisiae." Antimicrobial Agents and Chemotherapy 48, no. 10 (2004): 3871–76. http://dx.doi.org/10.1128/aac.48.10.3871-3876.2004.

Full text

Abstract:

ABSTRACT The antifungal agent caspofungin (CAS) specifically interferes with glucan synthesis and cell wall formation. To further study the cellular processes affected by CAS, we analyzed a Saccharomyces cerevisiae mutant collection (4,787 individual knockout mutations) to identify new genes affecting susceptibility to the drug. This collection was screened for increased CAS sensitivity (CAS-IS) or increased CAS resistance (CAS-IR). MICs were determined by the broth microdilution method. Disruption of 20 genes led to CAS-IS (four- to eightfold reductions in the MIC). Eleven of the 20 genes are

APA, Harvard, Vancouver, ISO, and other styles

44

Al Zyood, Dr Mahmoud M. Al Zyood*,. "Impact of Non-Performing Loans on Saudi Bank Profitability." Indian Journal of Economics and Finance 2, no. 2 (2022): 21–24. http://dx.doi.org/10.54105/ijef.d2521.111422.

Full text

Abstract:

Non-performing loans (NPLs) have become increasingly worrying to the Saudi banking sector. Sanctioned loans have a repayment schedule, including principal and interest amounts. Excessive defaults on loans leads to a liquidity crisis throughout the banking sector, and can even cause bank failure. As a result, banks have to cover non-performing loans and maintain reserves under the instructions of the Saudi Arabia Central Bank, which severely affects profitability. This study analyzes the comparative position of non-performing loans in the Saudi banking sector over the period 2009-2017 to determ

APA, Harvard, Vancouver, ISO, and other styles

45

Dr., Mahmoud M. Al Zyood. "Impact of Non-Performing Loans on Saudi Bank Profitability." Indian Journal of Economics and Finance (IJEF) 2, no. 2 (2022): 21–24. https://doi.org/10.54105/ijef.D2521.111422.

Full text

Abstract:

<strong>Abstract:</strong> Non-performing loans (NPLs) have become increasingly worrying to the Saudi banking sector. Sanctioned loans have a repayment schedule, including principal and interest amounts. Excessive defaults on loans leads to a liquidity crisis throughout the banking sector, and can even cause bank failure. As a result, banks have to cover non-performing loans and maintain reserves under the instructions of the Saudi Arabia Central Bank, which severely affects profitability. This study analyzes the comparative position of non-performing loans in the Saudi banking sector over the

APA, Harvard, Vancouver, ISO, and other styles

46

Barreto, Angela, Joana Santos, Mónica J. B. Amorim, and Vera L. Maria. "Polystyrene Nanoplastics Can Alter the Toxicological Effects of Simvastatin on Danio rerio." Toxics 9, no. 3 (2021): 44. http://dx.doi.org/10.3390/toxics9030044.

Full text

Abstract:

Once in the environment, nanoplastics (NPls) may interact with other contaminants, such as pharmaceuticals, potentially acting as carriers and modulating their toxicity. Thus, the main aim of the current study is to investigate how polystyrene (PS) NPls (mean diameter: 60 nm) interact with simvastatin (SIM), an anticholesterolemic drug, and modulate its toxicity to zebrafish (Danio rerio) embryos. PS NPls were carboxyl group functionalized, to promote the interaction/binding of NPls with SIM (worst-case scenarios) and it was fluorescently dyed, allowing to detect the intake. Exposure was 96 h

APA, Harvard, Vancouver, ISO, and other styles

47

Barreto, Angela, Joana Santos, Mónica J. B. Amorim, and Vera L. Maria. "How Can Nanoplastics Affect the Survival, Reproduction, and Behaviour of the Soil Model Enchytraeus crypticus?" Applied Sciences 10, no. 21 (2020): 7674. http://dx.doi.org/10.3390/app10217674.

Full text

Abstract:

Nanoplastics (NPls) are ubiquitous in terrestrial environments, with numerous consequences for biodiversity and ecosystems. Research is urgently required to clarify the NPls environmental behaviour, fate and ecotoxicological effects to soil ecosystems. The aim of this research was to assess and comprehend the effects of polystyrene NPls to the terrestrial species Enchytraeus crypticus using survival, reproduction and avoidance behaviour as endpoints. A range of concentrations, 0.015 to 1500 mg NPls/kg LUFA 2.2 (Landwirtschaftliche Untersuchungs- und Forschungsanstalt Speyer, Germany) soil, was

APA, Harvard, Vancouver, ISO, and other styles

48

DeHoratius, C., and P. A. Silver. "Nuclear transport defects and nuclear envelope alterations are associated with mutation of the Saccharomyces cerevisiae NPL4 gene." Molecular Biology of the Cell 7, no. 11 (1996): 1835–55. http://dx.doi.org/10.1091/mbc.7.11.1835.

Full text

Abstract:

To identify components involved in nuclear protein import, we used a genetic selection to isolate mutants that mislocalized a nuclear-targeted protein. We identified temperature-sensitive mutants that accumulated several different nuclear proteins in the cytoplasm when shifted to the semipermissive temperature of 30 degrees C; these were termed npl (nuclear protein localization) mutants. We now present the properties of yeast strains bearing mutations in the NPL4 gene and report the cloning of the NPL4 gene and the characterization of the Np14 protein. The npl4-1 mutant was isolated by the pre

APA, Harvard, Vancouver, ISO, and other styles

49

Staresincic, Lidija, Jane Walker, A. Barbara Dirac-Svejstrup, Richard Mitter, and Jesper Q. Svejstrup. "GTP-dependent Binding and Nuclear Transport of RNA Polymerase II by Npa3 Protein." Journal of Biological Chemistry 286, no. 41 (2011): 35553–61. http://dx.doi.org/10.1074/jbc.m111.286161.

Full text

Abstract:

We identified XAB1 in a proteomic screen for factors that interact with human RNA polymerase II (RNAPII). Because XAB1 has a conserved Saccharomyces cerevisiae homologue called Npa3, yeast genetics and biochemical analysis were used to dissect the significance of the interaction. Degron-dependent Npa3 depletion resulted in genome-wide transcription decreases, correlating with a loss of RNAPII from genes as measured by chromatin immunoprecipitation. Surprisingly, however, transcription in vitro was unaffected by Npa3, suggesting that it affects a process that is not required for transcription i

APA, Harvard, Vancouver, ISO, and other styles

50

Bredl, Sebastian. "The Role of Non-performing Loans for Bank Lending Rates." Jahrbücher für Nationalökonomie und Statistik 242, no. 2 (2021): 223–76. http://dx.doi.org/10.1515/jbnst-2021-0004.

Full text

Abstract:

Abstract Based on bank level data from the euro area, I investigate the role of non-performing loans (NPLs) for lending rates on newly granted loans. The focus is on an effect caused by the stock of NPLs that extends beyond losses that banks have already incorporated into their reported capital positions. The paper assesses the channels through which such an effect occurs. The results indicate that a higher stock of NPLs is associated with higher lending rates. This relation is driven by net NPLs, which constitute the part of NPLs that is not covered by loan loss reserves. Although the stock o

APA, Harvard, Vancouver, ISO, and other styles

We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!