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Journal articles on the topic 'NSPFS'

Author: Grafiati

Published: 3 June 2025

Last updated: 31 July 2025

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1

Zabolotskiy, Egor. "Using Financial Instruments of PPP Projects for NSPF’s Investment." Moscow University Economics Bulletin 2017, no. 2 (2017): 22–44. http://dx.doi.org/10.38050/01300105201722.

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The purpose of this paper is to analyze investments of Russian non-state pension funds (NSPF) into financial instruments for public-private partnership (PPP) projects. The scope of the study refers to basic models of PPP, pension resources investment models using PPP and State regulations of investment pension resources in PPP projects. The theoretical framework of research relates to the Russian normative legal acts, regulating the activities of NSPFs and PPP applications, and works of foreign and domestic organizations and scientists in PPP, NSPFs and pension resources investment areas. The

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2

Brandenburg, Dale C. "NSPFs New Technology Council: Current Efforts." Performance Improvement Quarterly 2, no. 3 (2008): 106–14. http://dx.doi.org/10.1111/j.1937-8327.1989.tb00414.x.

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3

Druzhynina, Viktoriia, Olena Zahorianska, and Andrii Kutsevol. "HR-MANAGEMENT AND SOCIAL GUARANTEES OF EMPLOYEES: MODERN CHALLENGES AND INNOVATIVE SOLUTIONS." Economic scope, no. 198 (March 10, 2025): 31–36. https://doi.org/10.30838/ep.198.31-36.

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In the article the directions for the development of the personnel management system through mechanisms for ensuring social guarantees for employees are identified. The activities of the National Pension Fund of Ukraine for 2020-2024 are analysed and the pension assets by levels of the pension system are distributed. Non-state pension funds (NSPFs) play a key role in the funded pension system, contributing to the formation of additional pension benefits through the effective management of investment assets. It is proven that over the past five years a stable growth in NPF has been asserted and

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4

Tereshchenko, Hanna, and Leonid Dolinskyi. "THE ROLE OF FINANCIAL AND INVESTMENT LITERACY IN SHAPING AN EFFECTIVE NON-STATE PENSION SYSTEM." Educational Analytics of Ukraine, no. 1 (2025): 85–98. https://doi.org/10.32987/2617-8532-2025-1-85-98.

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The article explores the current state and prospects for the development of the non-state pension provision (NSPP) system in Ukraine, taking into account the role of financial and investment literacy of citizens in building trust in long-term savings instruments. Emphasis is placed on the need to improve public awareness of the functioning of non-state pension funds (NSPFs), investment principles, and risk assessment, which are critically important for effective pension planning. A comparative analysis of financial literacy levels and population participation in NSPP systems in Ukraine and Eur

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5

Oruche, E.N., T.K. Atala, J.G. Akpoko, and J. Chikaire. "Impact of the National Special Programme for Food Security on Livestock Farmers in Ideato South Local Government Area of Imo State, Nigeria." Greener Journal of Agricultural Sciences 2, no. 6 (2012): 251–58. https://doi.org/10.5281/zenodo.3373411.

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This study was designed to assess the impact of the National Special Programme for food Security on livestock farmers in Ideato South Local Government Area, Imo State. Sixty participating farmers from three villages where the NSPFS programme was implemented were interviewed to examine their socio-economic characteristics, level of living, level of awareness, adoption level and income level. Another sixty non participant farmers from the three villages where National Special Programme for Food Security (NSPFS) was not implemented were also interviewed making a total sample size of 120 livestock

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I., Tafida, and Danwanka H.A. "ASSESSMENT OF FARMERS' PARTICIPATION LEVEL IN NATIONAL SPECIAL PROGRMME FOR FOOD SECURITY: A CASE STUDY OF WARAWA LOCAL GVERNMENT AREA OF KANO STATE." Continental J. Agricultural Economics 2 (June 16, 2017): 69–73. https://doi.org/10.5281/zenodo.809993.

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The study focused on the assessment of farmers’ participation in National Special Programme for Food Security (NSPFS) in Warawa Local Government Area of Kano State. Data were collected from 100 randomly selected farmers’ through the use of interview schedule, while the information collected was analyzed using descriptive statistics, regression (logit) and ranking. The result indicated that, the age of the farmers range from 15 to 72 with a mean of 37 years. They also have a mean household size of 13 members with an average farm size of 3.42ha as well as a mean farming experience of 22years. Si

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A, E. Agwu, and U. Ugwu P. "Farmers perception of the performance of the National Special Programme for Food Security (NSPFS) in Enugu State, NIgeria." African Journal of Biotechnology 7, no. 12 (2008): 1911–23. http://dx.doi.org/10.5897/ajb2008.000-5040.

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8

Rudyk, V. K. "Development of Private Pension Provision in the Conditions of Reforming the Pension System of Ukraine." Business Inform 11, no. 526 (2021): 235–40. http://dx.doi.org/10.32983/2222-4459-2021-11-235-240.

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The efficient functioning of the non-state pension system, which forms the third level of the domestic pension system, is essential for increasing the incomes of citizens of retirement age. The article is aimed at defining the main ways of further development of the non-state pension system in the context of reforming the national pension system, creating favorable conditions for attracting an increasing number of the population to participate in voluntary accumulation pension programs. The article provides an assessment of the status of the non-state pension system in Ukraine, analyzes its ma

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9

Animashaun, Jubril Olayinka, and M. O. Adewumi. "Assessment of the Contributions of National Special Program for Food Security (nspfs) to Food Security in Kwara-state, Nigeria." Delhi Business Review 14, no. 2 (2013): 19–28. http://dx.doi.org/10.51768/dbr.v14i2.142201312.

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10

Gong, Yongshun, Tiantian Xu, Xiangjun Dong, and Guohua Lv. "e-NSPFI: Efficient Mining Negative Sequential Pattern from Both Frequent and Infrequent Positive Sequential Patterns." International Journal of Pattern Recognition and Artificial Intelligence 31, no. 02 (2017): 1750002. http://dx.doi.org/10.1142/s0218001417500021.

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Negative sequential patterns (NSPs), which focus on nonoccurring but interesting behaviors (e.g. missing consumption records), provide a special perspective of analyzing sequential patterns. So far, very few methods have been proposed to solve for NSP mining problem, and these methods only mine NSP from positive sequential patterns (PSPs). However, as many useful negative association rules are mined from infrequent itemsets, many meaningful NSPs can also be found from infrequent positive sequences (IPSs). The challenge of mining NSP from IPS is how to constrain which IPS could be available use

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11

Stephen J, Beebe. "Considerations for Exploring Nanosecond Pulsed Electric Fields (nsPEFs) for Treatments of Cancer, Benign Skin Diseases, Atrial Fibrillation, and for New Mechanistic Understandings." Records of Cell & Bioscience 1, no. 1 (2024): 001–7. http://dx.doi.org/10.17352/rcb.000001.

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Pulsed power includes acquiring electrical energy, compressing it, and releasing it in instantaneous bursts that are low in energy but very high in power. When the pulse duration is near the plasma membrane charging time constant, which is the time during which the cell interior is exposed to the applied pulsed electric field, it affects intracellular structures and functions. The technology is called nanosecond Pulsed Electric Fields (nsPEFs), nanosecond electric pulses (nsEP), or Nanopulse Stimulation (NPSTM) according to Pulse Biosciences, Inc., a company taking the technology to the market

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Ajani, EN, and EM Igbokwe. "Occupational diversification among rural women in sub-saharan Africa: A review." African Journal of Food, Agriculture, Nutrition and Development 13, no. 60 (2013): 8224–37. http://dx.doi.org/10.18697/ajfand.60.11450.

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Rural women need to diversify their occupations since farming in sub - Saharan Africa is rain - fed and , therefore , seasonal. This is to enable them to acquire additional income to take care of economic responsibilities during off - season periods. This paper reviews current literature in the field in both farm and non - farm occupations and effects of occupational diversification, which varies from negative to positive effects . One major negative effect is withdrawal of critical labour from the family farm which serves as a distress push factor while t he positive effects include raisin g

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Galuta, A., A. Yassin Kassab, D. Ghinda, R. Sandarage, J. Kwan, and E. Tsai. "P.235 Differences in Human, Pig, and Rat Spinal Cord Stem Cells in Response to Inflammatory and Regenerative Factors In Vitro." Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques 48, s3 (2021): S88. http://dx.doi.org/10.1017/cjn.2021.526.

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Background: While the use of neural stem/progenitor cells has been reported as a promising therapeutic approach for spinal cord injury, direct comparison of adult primary animal spinal cord NSPCs have not been compared to human NSPCs under the same conditions to characterize intrinsic differences between human/animal NSPC response to inflammatory/regenerative factors. Methods: To mimic post-injury inflammation, primary-derived NSPCs from adult humans, pigs, and rats were treated with pro-inflammatory factors.To direct regeneration, NSPCs were treated with retinoic acid, platelet-derived growth

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Fukusumi, Hayato, Yukako Handa, Tomoko Shofuda, and Yonehiro Kanemura. "Small-scale screening of anticancer drugs acting specifically on neural stem/progenitor cells derived from human-induced pluripotent stem cells using a time-course cytotoxicity test." PeerJ 6 (January 4, 2018): e4187. http://dx.doi.org/10.7717/peerj.4187.

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Since the development of human-induced pluripotent stem cells (hiPSCs), various types of hiPSC-derived cells have been established for regenerative medicine and drug development. Neural stem/progenitor cells (NSPCs) derived from hiPSCs (hiPSC-NSPCs) have shown benefits for regenerative therapy of the central nervous system. However, owing to their intrinsic proliferative potential, therapies using transplanted hiPSC-NSPCs carry an inherent risk of undesired growth in vivo. Therefore, it is important to find cytotoxic drugs that can specifically target overproliferative transplanted hiPSC-NSPCs

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15

Sandarage, RV, A. Galuta, and EC Tsai. "P.145 Uncovering differences in oligodendrogenesis between human and rodent spinal cord stem cells." Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques 50, s2 (2023): S96. http://dx.doi.org/10.1017/cjn.2023.233.

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Background: Spinal cord regeneration in pre-clinical rodent studies is feasible by promoting oligodendrocyte regrowth, which is necessary for axon myelination. It is uncertain whether human neural stem/progenitor cells (NSPCs) are capable of differentiation into oligodendrocytes, similar to rat. In this study, we compare the functional and transcriptional features of primary spinal cord NSPCs from adult humans and rats. Methods: Oligodendrogenesis between human & rat NSPCs from adult donors and rats was cultured using the Neurosphere assay. NSPCs were exposed to 1% FBS to trigger different

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16

Rohmah, Martina Kurnia. "Pengaruh Variasi Jumlah Tembakan Nanosecond Pulsed Electric Fields (Nspefs) Terhadap Ekspresi Gen Socs3 pada Sel Kanker Serviks Hela S3." JRST: JURNAL RISET SAINS DAN TEKNOLOGI 1, no. 2 (2017): 45. http://dx.doi.org/10.30595/jrst.v1i2.1702.

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AbstrakNanosecond Pulsed Electric Fields (NsPEFs) merupakan teknologi bioelektrik yang berkembang dari teknologi elektroporasi. NsPEFs diberikan dengan intensitas tinggi namun dalam waktu yang sangat singkat yaitu 1 - 300 nanosekon. NsPEFs terbukti memiliki sejumlah efek biologis dan telah banyak dikembangkan dalam berbagai terapi salah satunya pada terapi kanker. Pada kanker serviks, protein HPV dapat menekan sejumlah ekspresi supresor tumor salah satunya yaitu gen Socs3. Penelitian ini bertujuan untuk mengetahui pengaruh perbedaan jumlah tembakan NsPEFs pada ekspresi gen Socs3. Sel HeLa S3 d

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17

Scharlach, Werner. "Don't change NSFs mission." Eos, Transactions American Geophysical Union 74, no. 43 (1993): 491. http://dx.doi.org/10.1029/93eo00644.

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18

Li, Wen-Qing, Ze-jian Wang, Sha Liu, Yue Hu, Ming Yin та Yang Lu. "N-Stearoyl-L-Tyrosine Inhibits the Senescence of Neural Stem/Progenitor Cells Induced by Aβ1–42via the CB2 Receptor". Stem Cells International 2016 (2016): 1–9. http://dx.doi.org/10.1155/2016/7419389.

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Alzheimer’s disease, one of the neurodegenerative diseases, shows the progressive senescence of neural progenitor/stem cells. N-Stearoyl-L-tyrosine (NsTyr) showed neuroprotective effect against chronic brain ischemia in previous reports. In the present study, we find the antisenescent effects of NsTyr-2K in NSPCs induced by Aβ1–42in vitro. Cell viability of NSPCs was evaluated by CCK8 assay; SA-β-gal staining was used to evaluate senescence of NSPCs. CB receptors were detected by immunohistochemistry in NSPCs. AM251 or AM630 was used to offset the anti-senescence effects afforded by NsTyr-2K.

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Jagadeesan, Sasi Kumar, Ahmad Galuta, Ryan Vimukthi Sandarage, and Eve Chung Tsai. "Transcriptomic and Functional Landscape of Adult Human Spinal Cord NSPCs Compared to iPSC-Derived Neural Progenitor Cells." Cells 14, no. 2 (2025): 64. https://doi.org/10.3390/cells14020064.

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The adult human spinal cord harbors diverse populations of neural stem/progenitor cells (NSPCs) essential for neuroregeneration and central nervous system repair. While induced pluripotent stem cell (iPSC)-derived NSPCs offer significant therapeutic potential, understanding their molecular and functional alignment with bona fide spinal cord NSPCs is crucial for developing autologous cell therapies that enhance spinal cord regeneration and minimize immune rejection. In this study, we present the first direct transcriptomic and functional comparison of syngeneic adult human NSPC populations, inc

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Deshpande, Sachin S., Subash C. Malik, Pasquale Conforti, et al. "P75 neurotrophin receptor controls subventricular zone neural stem cell migration after stroke." Cell and Tissue Research 387, no. 3 (2021): 415–31. http://dx.doi.org/10.1007/s00441-021-03539-z.

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AbstractStroke is the leading cause of adult disability. Endogenous neural stem/progenitor cells (NSPCs) originating from the subventricular zone (SVZ) contribute to the brain repair process. However, molecular mechanisms underlying CNS disease-induced SVZ NSPC-redirected migration to the lesion area are poorly understood. Here, we show that genetic depletion of the p75 neurotrophin receptor (p75NTR−/−) in mice reduced SVZ NSPC migration towards the lesion area after cortical injury and that p75NTR−/− NSPCs failed to migrate upon BDNF stimulation in vitro. Cortical injury rapidly increased p75

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Kulbatski, Iris, and Charles H. Tator. "Region-specific Differentiation Potential of Adult Rat Spinal Cord Neural Stem/Precursors and Their Plasticity in Response to In Vitro Manipulation." Journal of Histochemistry & Cytochemistry 57, no. 5 (2009): 405–23. http://dx.doi.org/10.1369/jhc.2008.951814.

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This study characterized the differentiation of neural stem/precursor cells (NSPCs) isolated from different levels of the spinal cord (cervical vs lumbar cord) and different regions along the neuraxis (brain vs cervical spinal cord) of adult male Wistar enhanced green fluorescent protein rats. The differentiation of cervical spinal cord NSPCs was further examined after variation of time in culture, addition of growth factors, and changes in cell matrix and serum concentration. Brain NSPCs did not differ from cervical cord NSPCs in the percentages of neurons, astrocytes, or oligodendrocytes but

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Sandarage, RV, A. Galuta, and E. Tsai. "P.144 Comparative analysis of spinal cord-derived and induced pluripotent-derived neural stem & progenitor cells for SCI therapy." Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques 51, s1 (2024): S55—S56. http://dx.doi.org/10.1017/cjn.2024.245.

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Background: Induced pluripotent stem cells (iPSCs) have revolutionized spinal cord injury (SCI) treatment by generating neural stem/progenitor cells (NSPCs). However, understanding how iPSC-derived NSPCs compare to authentic spinal cord NSPCs remains unclear. This study thoroughly characterizes bona fide spinal cord NSPCs and their isogenic iPSC-derived counterparts, iPSC-SC and iPSC-Br. Methods: Human spinal cord and skin tissue were obtained with ethics approval to establish primary NSPC cultures. iPSCs were derived from these primary cells and differentiated into iPSC-SC and iPSC-Br NSPCs.

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Sandarage, Ryan Vimukthie, Ahmad Galuta, and Eve C. Tsai. "372 Differences in Oligodendrogenesis Between Human and Rodent Spinal Cord Stem Cells." Neurosurgery 70, Supplement_1 (2024): 111–12. http://dx.doi.org/10.1227/neu.0000000000002809_372.

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INTRODUCTION: Research in pre-clinical rodent models suggests that targeting the endogenous neural stem/progenitor cells (NSPCs) in the spinal cord may hold the key to stimulating oligodendrocyte regeneration. However, it remains to be seen whether human spinal cord NSPCs possess the same regenerative potential as their rat counterparts. METHODS: To assess the potential for oligodendrogenesis between human and rat spinal cord NSPCs, primary tissue from adult donors and female rats was harvested and cultured using the Neurosphere assay. To induce spontaneous differentiation, primary-derived NSP

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Pilz, Gregor-Alexander, Sara Bottes, Marion Betizeau, et al. "Live imaging of neurogenesis in the adult mouse hippocampus." Science 359, no. 6376 (2018): 658–62. http://dx.doi.org/10.1126/science.aao5056.

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Neural stem and progenitor cells (NSPCs) generate neurons throughout life in the mammalian hippocampus. We used chronic in vivo imaging and followed genetically labeled individual NSPCs and their progeny in the mouse hippocampus for up to 2 months. We show that NSPCs targeted by the endogenous Achaete-scute homolog 1 (Ascl1) promoter undergo limited rounds of symmetric and asymmetric divisions, eliciting a burst of neurogenic activity, after which they are lost. Further, our data reveal unexpected asymmetric divisions of nonradial glia-like NSPCs. Cell fates of Ascl1-labeled lineages suggest a

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Kirby, Elizabeth D., Akela A. Kuwahara, Reanna L. Messer, and Tony Wyss-Coray. "Adult hippocampal neural stem and progenitor cells regulate the neurogenic niche by secreting VEGF." Proceedings of the National Academy of Sciences 112, no. 13 (2015): 4128–33. http://dx.doi.org/10.1073/pnas.1422448112.

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The adult hippocampus hosts a population of neural stem and progenitor cells (NSPCs) that proliferates throughout the mammalian life span. To date, the new neurons derived from NSPCs have been the primary measure of their functional relevance. However, recent studies show that undifferentiated cells may shape their environment through secreted growth factors. Whether endogenous adult NSPCs secrete functionally relevant growth factors remains unclear. We show that adult hippocampal NSPCs secrete surprisingly large quantities of the essential growth factor VEGF in vitro and in vivo. This self-de

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Liu, Zhenguo, Yawen Zou, Ying Sun, Xiaolong Chen, Xinhua Chen, and Zhigang Ren. "Effects of Nanosecond Pulsed Electric Fields in Cell Vitality, Apoptosis, and Proliferation of TPC-1 Cells." Analytical Cellular Pathology 2021 (October 13, 2021): 1–7. http://dx.doi.org/10.1155/2021/9913716.

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Objective. To evaluate the effects of nanosecond pulsed electric fields (nsPEFs) with different pulse durations in cell vitality, apoptosis, and proliferation of TPC-1 cells, optimize pulse parameters and expand the application range of nsPEFs. Methods. The pulse duration of 0, 300 ns, 500 ns, and 900 ns is generated with nsPEF generator. CCK-8 was used to investigate the effect of nsPEFs on the viability of TPC-1 cells. Flow cytometry was used to evaluate the apoptosis of TPC-1 after pulse treatment. The effect of nsPEFs on the proliferation ability of TPC-1 cells was detected by 5-ethy-nyl-2

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Roitbak, Tamara, Lu Li та Lee Anna Cunningham. "Neural Stem/Progenitor Cells Promote Endothelial Cell Morphogenesis and Protect Endothelial Cells against Ischemia via HIF-1α-Regulated VEGF Signaling". Journal of Cerebral Blood Flow & Metabolism 28, № 9 (2008): 1530–42. http://dx.doi.org/10.1038/jcbfm.2008.38.

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Vascular cells provide a neural stem/progenitor cell (NSPC) niche that regulates expansion and differentiation of NSPCs within the germinal zones of the embryonic and adult brain under both physiologic and pathologic conditions. Here, we examined the NSPC—endothelial cell (NSPC/EC) interaction under conditions of ischemia, both in vitro and after intracerebral transplantation. In culture, embryonic mouse NSPCs supported capillary morphogenesis and protected ECs from cell death induced by serum starvation or by transient oxygen and glucose deprivation (OGD). Neural stem/progenitor cells constit

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Lang, Grazia, Torsten Schlesinger, Markus Lamprecht, et al. "Types of professionalization." Sport, Business and Management: An International Journal 8, no. 3 (2018): 298–316. http://dx.doi.org/10.1108/sbm-11-2017-0076.

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Purpose The purpose of this paper is to identify types of professionalization in Swiss national sport federations (NSFs) and analyze organizational characteristics associated with specific types of professionalization. Such types reveal common patterns among the increasingly complex organizational designs of NSFs and thus contribute to the understanding of professionalization in NSFs. Design/methodology/approach An online survey of all Swiss NSFs was conducted to identify types of professionalization in these organizations using hierarchical cluster analysis, based on a multi-dimensional frame

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Tran The, Tung, Bao-Huy Truong, Khanh Dang Tuan, and Dieu Vo Ngoc. "A Nondominated Sorting Stochastic Fractal Search Algorithm for Multiobjective Distribution Network Reconfiguration with Distributed Generations." Mathematical Problems in Engineering 2021 (February 11, 2021): 1–20. http://dx.doi.org/10.1155/2021/6638559.

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This paper aims to propose a new multiobjective algorithm for multiobjective distributed network reconfiguration (DNR) with the placements of distributed generation (DG) in radial distribution networks (RDNs). The new proposed algorithm, called the nondominated sorting stochastic fractal search (NSSFS), is a new multiobjective version of the original SFS algorithm. NSSFS incorporated fast nondominated sorting strategies, crowding distance computation, and selection mechanism into SFS to find and maintain the best nondominated solutions. The proposed NSSFS algorithm was tested with eight multio

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Tanada, Shuichi, Takayuki Nakagomi, Akiko Nakano-Doi, et al. "Human-Brain-Derived Ischemia-Induced Stem Cell Transplantation Is Associated with a Greater Neurological Functional Improvement Compared with Human-Bone Marrow-Derived Mesenchymal Stem Cell Transplantation in Mice After Stroke." International Journal of Molecular Sciences 25, no. 22 (2024): 12065. http://dx.doi.org/10.3390/ijms252212065.

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The transplantation of injury/ischemia-induced stem cells (iSCs) extracted from post-stroke human brains can improve the neurological functions of mice after stroke. However, the usefulness of iSCs as an alternative stem cell source remains unclear. The current study aimed to assess the efficacy of iSC and mesenchymal stem cell (MSC) transplantation. In this experiment, equal numbers of human brain-derived iSCs (h-iSCs) (5.0 × 104 cells/μL) and human bone marrow-derived MSCs (h-MSCs) (5.0 × 104 cells/μL) were intracranially transplanted into post-stroke mouse brains after middle cerebral arter

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Sakayori, Nobuyuki, Ryuichi Kimura, and Noriko Osumi. "Impact of Lipid Nutrition on Neural Stem/Progenitor Cells." Stem Cells International 2013 (2013): 1–12. http://dx.doi.org/10.1155/2013/973508.

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The neural system originates from neural stem/progenitor cells (NSPCs). Embryonic NSPCs first proliferate to increase their numbers and then produce neurons and glial cells that compose the complex neural circuits in the brain. New neurons are continually produced even after birth from adult NSPCs in the inner wall of the lateral ventricle and in the hippocampal dentate gyrus. These adult-born neurons are involved in various brain functions, including olfaction-related functions, learning and memory, pattern separation, and mood control. NSPCs are regulated by various intrinsic and extrinsic f

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Campagnolo, Alberto, Paolo Ferro, Luca Romanin, and Giovanni Meneghetti. "Residual Notch Stress Intensity Factors in Welded Joints Evaluated by 3D Numerical Simulations of Arc Welding Processes." Materials 14, no. 4 (2021): 812. http://dx.doi.org/10.3390/ma14040812.

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Approaches based on calculating Residual Notch Stress Intensity Factors (R-NSIFs) assume the weld toe to be a sharp V-notch that gives rise to a residual singular stress distribution close to the weld toe. Once R-NSIFs are determined, they might be included in local fatigue criteria for the structural strength assessment of welded joints based on NSIFs due to external cyclic loading. However, the numerical calculation of R-NSIFs through finite element (FE) simulations of the welding process requires extremely refined meshes to properly capture the residual stress singularity. In this context,

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Guo, Yu-Yi, Fu-Kun Shi, Qun Wang, Zhen-Yu Ji, and Jie Zhuang. "A review on bioelectrical effects of cellular organelles by high voltage nanosecond pulsed electric fields." Acta Physica Sinica 71, no. 6 (2022): 068701. http://dx.doi.org/10.7498/aps.71.20211850.

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The biomedical application of high-voltage nanosecond pulsed electric fields (nsPEFs) has become an emerging interdisciplinary research field in recent years. Compared with microsecond and millisecond pulsed electric fields, high-voltage nsPEFs can not only lead the cell membrane structure to polarize and dielectric break down the cell membrane structure, i.e. membrane electroporation, but also penetrate into the cell, triggering off organelle bioelectrical effects such as cytoskeleton depolymerization, intracellular calcium ion release, and mitochondrial membrane potential dissipation. Extens

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Li, Jingzheng, Yafang Shang, Lin Wang, et al. "Genome integrity and neurogenesis of postnatal hippocampal neural stem/progenitor cells require a unique regulator Filia." Science Advances 6, no. 44 (2020): eaba0682. http://dx.doi.org/10.1126/sciadv.aba0682.

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Endogenous DNA double-strand breaks (DSBs) formation and repair in neural stem/progenitor cells (NSPCs) play fundamental roles in neurogenesis and neurodevelopmental disorders. NSPCs exhibit heterogeneity in terms of lineage fates and neurogenesis activity. Whether NSPCs also have heterogeneous regulations on DSB formation and repair to accommodate region-specific neurogenesis has not been explored. Here, we identified a regional regulator Filia, which is predominantly expressed in mouse hippocampal NSPCs after birth and regulates DNA DSB formation and repair. On one hand, Filia protects stall

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Stronati, Eleonora, Roberta Conti, Emanuele Cacci, Silvia Cardarelli, Stefano Biagioni, and Giancarlo Poiana. "Extracellular Vesicle-Induced Differentiation of Neural Stem Progenitor Cells." International Journal of Molecular Sciences 20, no. 15 (2019): 3691. http://dx.doi.org/10.3390/ijms20153691.

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Neural stem progenitor cells (NSPCs) from E13.5 mouse embryos can be maintained in culture under proliferating conditions. Upon growth-factor removal, they may differentiate toward either neuronal or glial phenotypes or both. Exosomes are small extracellular vesicles that are part of the cell secretome; they may contain and deliver both proteins and genetic material and thus play a role in cell–cell communication, guide axonal growth, modulate synaptic activity and regulate peripheral nerve regeneration. In this work, we were interested in determining whether NSPCs and their progeny can produc

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Cornillez-Ty, Cromwell T., Lujian Liao, John R. Yates, Peter Kuhn, and Michael J. Buchmeier. "Severe Acute Respiratory Syndrome Coronavirus Nonstructural Protein 2 Interacts with a Host Protein Complex Involved in Mitochondrial Biogenesis and Intracellular Signaling." Journal of Virology 83, no. 19 (2009): 10314–18. http://dx.doi.org/10.1128/jvi.00842-09.

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ABSTRACT The severe acute respiratory syndrome coronavirus (SARS-CoV) generates 16 nonstructural proteins (nsp's) through proteolytic cleavage of a large precursor protein. Although several nsp's exhibit catalytic activities that are important for viral replication and transcription, other nsp's have less clearly defined roles during an infection. In order to gain a better understanding of their functions, we attempted to identify host proteins that interact with nsp's during SARS-CoV infections. For nsp2, we identified an interaction with two host proteins, prohibitin 1 (PHB1) and PHB2. Our r

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Carucci, Nicoletta, Emanuele Cacci, Paola S. Nisi, et al. "Transcriptional response of Hoxb genes to retinoid signalling is regionally restricted along the neural tube rostrocaudal axis." Royal Society Open Science 4, no. 4 (2017): 160913. http://dx.doi.org/10.1098/rsos.160913.

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During vertebrate neural development, positional information is largely specified by extracellular morphogens. Their distribution, however, is very dynamic due to the multiple roles played by the same signals in the developing and adult neural tissue. This suggests that neural progenitors are able to modify their competence to respond to morphogen signalling and autonomously maintain positional identities after their initial specification. In this work, we take advantage of in vitro culture systems of mouse neural stem/progenitor cells (NSPCs) to show that NSPCs isolated from rostral or caudal

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Kanemura, Yonehiro, Hideki Mori, Atsuyo Nakagawa, et al. "In Vitro Screening of Exogenous Factors for Human Neural Stem/Progenitor Cell Proliferation Using Measurement of Total ATP Content in Viable Cells." Cell Transplantation 14, no. 9 (2005): 673–82. http://dx.doi.org/10.3727/000000005783982701.

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One of the newest and most promising methods for treating intractable neuronal diseases and injures is the transplantation of ex vivo-expanded human neural stem/progenitor cells (NSPCs). Human NSPCs are selectively expanded as free-floating neurospheres in serum-free culture medium containing fibroblast growth factor 2 (FGF2) and/or epidermal growth factor (EGF); however, the culture conditions still need to be optimized for performance and cost before the method is used clinically. Here, to improve the NSPC culture method for clinical use, we used an ATP assay to screen the effects of various

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Watanabe, Kota, Masaya Nakamura, Hideyuki Okano, and Yoshiaki Toyama. "Establishment of three-dimensional culture of neural stem/progenitor cells in collagen Type-1 Gel." Restorative Neurology and Neuroscience 25, no. 2 (2007): 109–17. https://doi.org/10.3233/rnn-2007-00373.

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Purpose: Recent studies demonstrated that transplanting neural stem/precursor cells (NSPCs) into an injured spinal cord of adult rat promotes functional recovery. The functional recovery from spinal cord injury might be enhanced by transplanting NSPCs with a scaffold that fills the cavity, entraps the NSPCs in the cavity, and acts as an attachment for neurite extension. We recently focused on collagen type-1 as a scaffold for NSPC transplantation into the injured spinal cord. In the present study, we determined the optimal conditions for culturing NSPCs in 3D collagen type-1 gel with respect t

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Li, Qing-Gang, Zhen-Guo Liu, Gang Dong, et al. "Nanosecond pulsed electric field ablates rabbit VX2 liver tumors in a non-thermal manner." PLOS ONE 18, no. 3 (2023): e0273754. http://dx.doi.org/10.1371/journal.pone.0273754.

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Background Liver tumor remains an important cause of cancer-related death. Nanosecond pulsed electric fields (nsPEFs) are advantageous in the treatment of melanoma and pancreatic cancer, but their therapeutic application on liver tumors need to be further studied. Methods Hep3B cells were treated with nsPEFs. The biological behaviors of cells were detected by Cell Counting Kit-8, 5-ethynyl-20-deoxyuridine, and transmission electron microscopy (TEM) assays. In vivo, rabbit VX2 liver tumor models were ablated by ultrasound-guided nsPEFs and radiofrequency ablation (RFA). Contrast-enhanced ultras

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Rushing, Gabrielle V., Asa A. Brockman, Madelyn K. Bollig, et al. "Location-dependent maintenance of intrinsic susceptibility to mTORC1-driven tumorigenesis." Life Science Alliance 2, no. 2 (2019): e201800218. http://dx.doi.org/10.26508/lsa.201800218.

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Neural stem/progenitor cells (NSPCs) of the ventricular–subventricular zone (V-SVZ) are candidate cells of origin for many brain tumors. However, whether NSPCs in different locations within the V-SVZ differ in susceptibility to tumorigenic mutations is unknown. Here, single-cell measurements of signal transduction intermediates in the mechanistic target of rapamycin complex 1 (mTORC1) pathway reveal that ventral NSPCs have higher levels of signaling than dorsal NSPCs. These features are linked with differences in mTORC1-driven disease severity: introduction of a pathognomonic Tsc2 mutation onl

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Jay, Joanna, Erika L. Pfaunmiller, Norman J. Huang, Gal Cohen, and Donald W. Graff. "Five-Day Changes in Biomarkers of Exposure Among Adult Smokers After Completely Switching From Combustible Cigarettes to a Nicotine-Salt Pod System." Nicotine & Tobacco Research 22, no. 8 (2019): 1285–93. http://dx.doi.org/10.1093/ntr/ntz206.

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Abstract Introduction This study examined changes in biomarkers of exposure (BoE) after 5 days of nicotine-salt pod system (NSPS) use, compared with continuation of usual-cigarette smoking and cigarette abstinence, among adult combustible cigarette smokers. Aims and Methods A randomized, open-label, parallel-cohort, confinement study of healthy adult smokers, naive to NSPS use, was conducted. Participants (N = 90) were randomized to six cohorts (n = 15 each): exclusive ad libitum use of NSPS (four flavors: Virginia Tobacco, Mint, Mango, Creme), continuation of usual-brand cigarette smoking, or

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Felicia and Michael Jaya. "Identifikasi dan Manajemen pada Nyeri Sentral Paska Stroke." Damianus Journal of Medicine 22, no. 1 (2023): 69–75. http://dx.doi.org/10.25170/djm.v22i1.3943.

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Pendahuluan: Nyeri sentral paska stroke (NSPS) merupakan nyeri neuropatik sentral yang timbul setelah terjadinya stroke. Kondisi ini ditemukan pada 1-12% dari penderita stroke dan umumnya terjadi dalam 6 bulan pertama setelah terjadinya stroke. Nyeri yang ditimbulkan pada NSPS dapat mengakibatkan penurunan kualitas hidup, menghambat proses rehabilitasi, serta menimbulkan keterbatasan aktivitas dan interaksi sosial. Tujuan: Sebagai bahan pembelajaran yang membahas mengenai diagnosis, manifestasi klinis, patofisiologi hingga tatalaksana dari NSPS. Metode: Penulisan artikel ini menggu

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Setiawan, Setiawan. "Capital Structure and Firm Performance: A Comparative Study of Shariah-Compliant and Non-Shariah-Compliant Firms in Indonesia." Indonesian Journal of Economics and Management 3, no. 1 (2022): 106–13. http://dx.doi.org/10.35313/ijem.v3i1.4665.

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This study seeks to examine the extent of influence of capital structure towards firm performance in shariah-compliant firms (SCFs) and non-shariah-compliant firms (NSCFs) in Indonesia. Data used are from the companies listed in Indonesian Stock Exchange. For SCFs, it was the companies listed in Jakarta Islamic Index and Sharia Stock Index while NSCFs are companies that not listed there. Data collected are 273 SCFs and 71 NSCFs. Data analysis using Mann Whitney, Panel Fixed Effects Regression and Generalized Methods of Moments. The result of this study shows that debt-financed capital structur

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Kwak, Minhye, Sanghee Lim, Eunchai Kang, et al. "Effects of Neonatal Hypoxic-Ischemic Injury and Hypothermic Neuroprotection on Neural Progenitor Cells in the Mouse Hippocampus." Developmental Neuroscience 37, no. 4-5 (2015): 428–39. http://dx.doi.org/10.1159/000430862.

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Neonatal hypoxic-ischemic injury (HI) results in widespread cerebral encephalopathy and affects structures that are essential for neurocognitive function, such as the hippocampus. The dentate gyrus contains a reservoir of neural stem and progenitor cells (NSPCs) that are critical for postnatal development and normal adult function of the hippocampus, and may also facilitate the recovery of function after injury. Using a neonatal mouse model of mild-to-moderate HI and immunohistochemical analysis of NSPC development markers, we asked whether these cells are vulnerable to HI and how they respond

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Liu, Yu, Xinlangji Fu, Hang Zhou, et al. "Different Types of Non-Starch Polysaccharides Alter the Growth, Intestinal Flora and Serum Metabolite Profile of Grass Carp, Ctenopharyngodon idella." Metabolites 12, no. 10 (2022): 1003. http://dx.doi.org/10.3390/metabo12101003.

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Dietary non-starch polysaccharides (NSPs) broadly influence fish intestinal flora and physiological metabolism, but limited information is available on grass carp (Ctenopharyngodon idella). This study investigated the effects of different types of NSPs on the growth, nutrient metabolism status, gut microbiota, and serum metabolome of grass carp. Fish were fed with diets containing 4.4% insoluble NSPs (INSP), 9.24% soluble NSPs (SNSP), 13.64% NSPs (4.4% INSP + 9.24% SNSP, NSP) and non NSPs (FM), respectively, for 9 weeks. Results showed that dietary SNSP decreased protein efficiency ratio and s

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Lee, Changoo. "The origin problem of the ancient ‘Nine-Squares Field System’ and the Gojoseon Dynasty: Centering on Mengzi's comparisons to the Xia, Yin, and Zhou eras." Barun Academy of History 20 (June 30, 2024): 7–57. http://dx.doi.org/10.55793/jkhc.2024.20.7.

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This study aims to investigate the ‘nine-square field system’ (NSFS, Jeongjeonje井田制) of the Xia(夏), Yin(殷), and Zhou(周) Dynasties mentioned by Meng zi(孟子) over 2300 years ago and the NSFS mentioned in The I Ching or Book of Changes(周易), respectively, and to consider its origin from the perspective of Gojoseon Dynasty(Dangun-Joseon), away from these three countries-centered studies in China. Meng zi initially called it ‘Well Field’ (井地, Jing di) instead of NSFS, but later Zhū Xī(朱熹) called it NSFS and this name became common. Meng zi argued that for a monarch to practice virtuous politics, the

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LEPKOWSKI, WIL. "NSFs Nicholson named head of AAAS." Chemical & Engineering News 67, no. 5 (1989): 5. http://dx.doi.org/10.1021/cen-v067n005.p005.

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Zurer, R. S. "Changes in NSFs science education unit." Chemical & Engineering News 68, no. 26 (1990): 21–22. http://dx.doi.org/10.1145/86701.86705.

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Anonymous. "Sullivan to head NSFs polar programs." Eos, Transactions American Geophysical Union 74, no. 10 (1993): 114. http://dx.doi.org/10.1029/93eo00355.

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