Academic literature on the topic 'Nuclear disruption'

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Journal articles on the topic "Nuclear disruption"

1

Riccardo, V., and JET EFDA contributors. "Disruptions and disruption mitigation." Plasma Physics and Controlled Fusion 45, no. 12A (2003): A269—A284. http://dx.doi.org/10.1088/0741-3335/45/12a/018.

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2

Aymerich, E., G. Sias, F. Pisano, et al. "Disruption prediction at JET through deep convolutional neural networks using spatiotemporal information from plasma profiles." Nuclear Fusion 62, no. 6 (2022): 066005. http://dx.doi.org/10.1088/1741-4326/ac525e.

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Abstract In view of the future high power nuclear fusion experiments, the early identification of disruptions is a mandatory requirement, and presently the main goal is moving from the disruption mitigation to disruption avoidance and control. In this work, a deep-convolutional neural network (CNN) is proposed to provide early detection of disruptive events at JET. The CNN ability to learn relevant features, avoiding hand-engineered feature extraction, has been exploited to extract the spatiotemporal information from 1D plasma profiles. The model is trained with regularly terminated discharges
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3

Thornton, J. W. "Nonmammalian nuclear receptors: Evolution and endocrine disruption." Pure and Applied Chemistry 75, no. 11-12 (2003): 1827–39. http://dx.doi.org/10.1351/pac200375111827.

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Most research to identify endocrine-disrupting chemicals and their impacts has relied on mammalian models or in vitro systems derived from them. But nuclear receptors (NRs), the proteins that transduce hydrophobic hormonal signals and are major mediators of endocrine disruption, emerged early in animal evolution and now play biologically essential roles throughout the Metazoa. Nonmammalian vertebrates and invertebrates, many of which are of considerable ecological, economic, and cultural importance, are therefore potentially subject to endocrine disruption by synthetic environmental pollutants
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4

Yang, Zongyu, Fan Xia, Xianming Song, Zhe Gao, Shuo Wang, and Yunbo Dong. "In-depth research on the interpretable disruption predictor in HL-2A." Nuclear Fusion 61, no. 12 (2021): 126042. http://dx.doi.org/10.1088/1741-4326/ac31d8.

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Abstract In-depth research is implemented on the disruption predictor in HL-2A to improve the accuracy and interpretability of the model. For higher accuracy, four adjustments are tried to solve four corresponding problems in a baseline model. Reductive comparison experiments are designed to evaluate their contribution to performance. The result shows that these adjustments together can improve the AUC (area under receiver operating characteristic curve) of the baseline model by 0.039. For interpretability of model, an interpretation method is proposed to evaluate the real-time importance of e
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5

Fyfe, Ian. "TDP pathology leads to nuclear disruption." Nature Reviews Neurology 14, no. 3 (2018): 127. http://dx.doi.org/10.1038/nrneurol.2018.2.

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6

Wie, B. "Hypervelocity nuclear interceptors for asteroid disruption." Acta Astronautica 90, no. 1 (2013): 146–55. http://dx.doi.org/10.1016/j.actaastro.2012.04.028.

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7

Furukawa, Manabu, Yanping Zhang, Joseph McCarville, Tomohiko Ohta, and Yue Xiong. "The CUL1 C-Terminal Sequence and ROC1 Are Required for Efficient Nuclear Accumulation, NEDD8 Modification, and Ubiquitin Ligase Activity of CUL1." Molecular and Cellular Biology 20, no. 21 (2000): 8185–97. http://dx.doi.org/10.1128/mcb.20.21.8185-8197.2000.

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ABSTRACT Members of the cullin and RING finger ROC protein families form heterodimeric complexes to constitute a potentially large number of distinct E3 ubiquitin ligases. We report here that the highly conserved C-terminal sequence in CUL1 is dually required, both for nuclear localization and for modification by NEDD8. Disruption of ROC1 binding impaired nuclear accumulation of CUL1 and decreased NEDD8 modification in vivo but had no effect on NEDD8 modification of CUL1 in vitro, suggesting that ROC1 promotes CUL1 nuclear accumulation to facilitate its NEDD8 modification. Disruption of NEDD8
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8

Clark-Walker, G. D., and X. J. Chen. "Dual Mutations Reveal Interactions Between Components of Oxidative Phosphorylation in Kluyveromyces lactis." Genetics 159, no. 3 (2001): 929–38. http://dx.doi.org/10.1093/genetics/159.3.929.

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Abstract Loss of mtDNA or mitochondrial protein synthesis cannot be tolerated by wild-type Kluyveromyces lactis. The mitochondrial function responsible for ρ0-lethality has been identified by disruption of nuclear genes encoding electron transport and F0-ATP synthase components of oxidative phosphorylation. Sporulation of diploid strains heterozygous for disruptions in genes for the two components of oxidative phosphorylation results in the formation of nonviable spores inferred to contain both disruptions. Lethality of spores is thought to result from absence of a transmembrane potential, ΔΨ,
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9

Ohkawa, Taro, and Matthew D. Welch. "Baculovirus Actin-Based Motility Drives Nuclear Envelope Disruption and Nuclear Egress." Current Biology 28, no. 13 (2018): 2153–59. http://dx.doi.org/10.1016/j.cub.2018.05.027.

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10

Spann, Timothy P., Anne E. Goldman, Chen Wang, Sui Huang, and Robert D. Goldman. "Alteration of nuclear lamin organization inhibits RNA polymerase II–dependent transcription." Journal of Cell Biology 156, no. 4 (2002): 603–8. http://dx.doi.org/10.1083/jcb.200112047.

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RTegulation of gene activity is mediated by alterations in chromatin organization. In addition, chromatin organization may be governed in part by interactions with structural components of the nucleus. The nuclear lamins comprise the lamina and a variety of nucleoplasmic assemblies that together are major structural components of the nucleus. Furthermore, lamins and lamin-associated proteins have been reported to bind chromatin. These observations suggest that the nuclear lamins may be involved in the regulation of gene activity. In this report, we test this possibility by disrupting the norma
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