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Journal articles on the topic 'Nuclear medicine Dose calibrator 99mTc Quality control'

Author: Grafiati
Published: 4 June 2025
Last updated: 1 August 2025

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1

Belhaj, Omaima Essaad, Siham Belhaj, Tahar Elkhoukhi, et al. "Ionizing radiation metrology at the service of health: quality control of radiopharmaceutical dose calibrators in nuclear medicine unit -accurarcy, reproducibility and linearity tests-." E3S Web of Conferences 351 (2022): 01095. http://dx.doi.org/10.1051/e3sconf/202235101095.

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Ensuring the effective use of a dose calibrator used for the practice of nuclear medicine, and the injection of the correct dose to the patient is the subject of a long traceable calibration chain, which serves to establish the relationship between the values of the activity indicated by the dose calibrator and the activity corresponding to ISO 2919 certified sealed sources whose activity is known with an uncertainty of less than 1 %. Our calibration program consists in carrying out various quality control on the CRC 55TR activimeter, namely the daily control which is carried out in the absenc
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2

Febriana, S., and I. Mirda. "Gamma spectrometer calibration of liquid standard sources of Mix 133Ba, 137Cs and 60Co toward the measurement of 99Mo breakthrough of 99Mo/99mTc generator." Journal of Physics: Conference Series 2596, no. 1 (2023): 012032. http://dx.doi.org/10.1088/1742-6596/2596/1/012032.

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Abstract The expression radionuclide in nuclear medicine is preferred than radioisotope which widely used in physics. Radionuclides have been used regularly in nuclear medicine. Their radiation provide information about the staging of a person’s specific organs and to specify what is triggering the symptoms, injury or disease to treat diseased organs or cancerous tumours in a patient called theranostic. Technetium-99m radionuclide is the most frequently used radionuclide in nuclear medicine. The quality control of technetium-99m (99m Tc) product from 99Mo/99mTc generator is crucial. One that h
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3

Willegaignon, José, Marcelo Tatit Sapienza, George Barberio Coura-Filho, et al. "Dose calibrator linearity test: 99mTc versus 18F radioisotopes." Radiologia Brasileira 48, no. 1 (2015): 26–32. http://dx.doi.org/10.1590/0100-3984.2014.0018.

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Objective: The present study was aimed at evaluating the viability of replacing 18F with 99mTc in dose calibrator linearity testing. Materials and Methods: The test was performed with sources of 99mTc (62 GBq) and 18F (12 GBq) whose activities were measured up to values lower than 1 MBq. Ratios and deviations between experimental and theoretical 99mTc and 18F sources activities were calculated and subsequently compared. Results: Mean deviations between experimental and theoretical 99mTc and 18F sources activities were 0.56 (± 1.79)% and 0.92 (± 1.19)%, respectively. The mean ratio between acti
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4

Hacıosmanoğlu, Tuğba. "Dose Calibrators and Quality Control Tests." Advances in Medical Pyhsics and Applied Sciences 1, no. 2 (2025): 66–70. https://doi.org/10.63187/ampas.17.

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Radiopharmaceuticals are used in nuclear medicine diagnosis and treatment ptotochols. The radiopharmaceutical activity given to the patient should be determined by dose calibrator before administration. The activity given to the patient is very important to know how the radiation affect the patient.It is not possible to understand the presence of radiation with the sense organs. The contact with the substance is essential for radiation to be detected. While doing any practices involving the nuclear medicine administration of a radiopharmaceutical, it is essential to use sensitive instrumentati
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5

Abdur Rahim. "Quality Control Procedure of Clinical Nuclear Medicine Instruments and Comparisons with Standard Protocol (At DINAR Cancer Hospital D. I. Khan)." Tuijin Jishu/Journal of Propulsion Technology 45, no. 04 (2024): 1126–38. http://dx.doi.org/10.52783/tjjpt.v45.i04.8353.

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Quality control of clinical Nuclear medicine instruments” i.e. used, used in this research work i.e. radioisotope dose calibrator and SPECT gamma camera is most important for reliable operational characteristics in this research work different tests has been done taking data from “ GE- Infinia Hawkeye” SPECT Gamma camera at “DINAR” Cancer hospital D.I.Khan.Auto zero, background, linearity, geometry, constancy and accuracy tests were performed in the case of radioisotopes dose calibrator while tests performed in case of SPECT gamma camera includes background, energy peak, C.O.R and uniformity t
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6

Abdur Rahim. "Quality Control Procedure of Clinical Nuclear Medicine Instruments and Comparisons with Standard Protocol (At DINAR Cancer Hospital D. I. Khan)." Tuijin Jishu/Journal of Propulsion Technology 45, no. 04 (2024): 1126–38. http://dx.doi.org/10.52783/tjjpt.v45.i04.8270.

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Quality control of clinical Nuclear medicine instruments” i.e. used, used in this research work i.e. radioisotope dose calibrator and SPECT gamma camera is most important for reliable operational characteristics in this research work different tests has been done taking data from “ GE- Infinia Hawkeye” SPECT Gamma camera at “DINAR” Cancer hospital D.I.Khan.Auto zero, background, linearity, geometry, constancy and accuracy tests were performed in the case of radioisotopes dose calibrator while tests performed in case of SPECT gamma camera includes background, energy peak, C.O.R and uniformity t
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7

Yaseen, Muhammad, Amir Ali, Mohammad Hassan Kharita, et al. "ASSESSMENT OF DOSE CALIBRATOR PERFORMANCE FOR ACCURATE PATIENT DOSE ADMINISTRATION AND BETTER STAFF PROTECTION IN A BUSY NUCLEAR MEDICINE DEPARTMENT QUALITY MATTERS." International Journal of Advanced Research 10, no. 08 (2021): 157–68. http://dx.doi.org/10.21474/ijar01/15161.

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Background: To assess the performance of the Capintec- CRC-15R dose calibrator which is in use atLiaquat National Hospital (LNH) Karachi, Pakistan for patient dose administration. Method: This quantitative study was conducted at Nuclear Medicine department, Liaquat National Hospital,Karachi during the period from July-December 2015. The quality control tests of calibrator were performed using standard sources i.e. Co-57, Ba-133 & CS-137 and data was analyzed for performance assessment of calibrator. Results: Capintec CRC-15R calibrator was found in perfect working condition during daily ph
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8

Nazaroh. "Quality assurance and quality control at dose calibrator to support nuclear medicine services." Journal of Physics: Conference Series 1436 (January 2020): 012004. http://dx.doi.org/10.1088/1742-6596/1436/1/012004.

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9

Razab, Mohammad, Norazlina Nawi, Rosidah Sunaiwi, et al. "Efficiency of marketable decontamination agent and graphene oxide on 99mTc and 131I spillages in nuclear medicine department." Nuclear Technology and Radiation Protection 37, no. 2 (2022): 159–66. http://dx.doi.org/10.2298/ntrp2202159r.

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Dealing with open sources of radioactive substances in nuclear medicine is a daily task since contamination due to radioactive spills may happen frequently. Proper and safe decontamination management is a vital procedure. However, regular purchase of decontamination agents incurs high costs and might be toxic due to their chemical properties. The purpose of this study is to compare graphene oxide, which is an environmentally friendly carbon-based material and marketable decontamination agent, in decontaminating radioactive spillage. Samples of pure 99mTc and 131I from the laboratory were spill
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10

Willegaignon, José, MarceloT Sapienza, GeorgeBarberio Coura-Filho, et al. "Dose Calibrator Linearity Testing: Radioisotope99mTc or18F? An Alternative for Reducing Costs in Nuclear Medicine Quality Control." World Journal of Nuclear Medicine 14, no. 3 (2015): 165. http://dx.doi.org/10.4103/1450-1147.163245.

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11

Tanguay, J., X. Hou, P. Esquinas, et al. "A fast and simple dose-calibrator-based quality control test for the radionuclidic purity of cyclotron-produced99mTc." Physics in Medicine and Biology 60, no. 21 (2015): 8229–47. http://dx.doi.org/10.1088/0031-9155/60/21/8229.

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12

Zelchan, R. V., A. A. Medvedeva, O. D. Bragina, et al. "Study of the diagnostic efficiency of single-photon emission computed tomography with [<sup>99m</sup>Tc]Tc-1-THIO-D-glucose in visualization of brain tumors." Siberian journal of oncology 21, no. 5 (2022): 24–33. http://dx.doi.org/10.21294/1814-4861-2022-21-5-24-33.

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The aim of the study was to evaluate the feasibility of using single-photon emission computed tomography (SPECT) with [99mTc]Tc-1-THIO-D-glucose in the detection of brain tumor malignancy. Material and methods. The study included 70 patients diagnosed with grade II–Iv malignant brain tumors and 10 patients with benign brain tumors. The control group consisted of 20 patients who had no pathological changes in the brain at the time of diagnosis. All patients underwent single-photon emission computed tomography of the brain 40 minutes after intravenous injection of [99mTc]Tc-1-THIO-D-glucose at a
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13

A.K.M., Mizanur Rahman, Reza S., Begum Mahfuza, et al. "STUDY OF SOME ESSENTIAL QUALITY CONTROL TEST PARAMETERS FOR THE PERFORMANCE OF DOSE CALIBRATORS IN NUCLEAR MEDICINE PRACTICES." March 4, 2019. https://doi.org/10.5281/zenodo.2644863.

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The aim of this study is to evaluate and compare the performance of two dose calibrators which are used in Nuclear Medicine Center by standard tests accuracy, constancy, linearity and geometry. To check the performance status of the dose calibrators the activity of radiopharmaceuticals must be accurately known before administered to the patients. Two dose calibrators of Institute Nuclear Medicine and Allied Sciences, Dhaka (Capintec, Inc.,Model no. CRC 25R and Veenstra , model no. VDC 404) performances were compared in accordance with varying geometry because most common measurement geometries
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14

Ali, Javaid, Shujat Ali, Habib Ahmad, et al. "Assessment of Molybdenum Concentration in 99Mo/99mtc Generators (PAKGEN): 6 Years Experience." Pakistan Journal of Nuclear Medicine, 2023, 1. http://dx.doi.org/10.24911/pjnmed.175-1638605076.

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Background Technitium-99m (99mTc) is a widely used radioisotope for the diagnostic procedures in nuclear medicine. The radioisotope is eluted from 99Mo/99mTc generator. Ideally there should be no Molybdenum-99 (99Mo) or any other contamination; however, sometimes traces of 99Mo are co-eluted from the generator. This impurity interferes labeling of 99mTc with pharmaceuticals result in poor quality radiopharmaceutical and unnecessary exposure to patients. The purpose of this study is to assess the contamination level of 99Mo in the eluted activity of 99mTc used for the diagnostic procedures at S
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15

Muhammad, Yaseen Amir Ali, Hassan Kharita Mohammad, Burki Shamsullah, Khan Javaid Iqbal Banaras, and Kamal Eslam. "ASSESSMENT OF DOSE CALIBRATOR PERFORMANCE FOR ACCURATE PATIENT DOSE ADMINISTRATION AND BETTER STAFF PROTECTION IN A BUSY NUCLEAR MEDICINE DEPARTMENT QUALITY MATTERS." August 18, 2022. https://doi.org/10.5281/zenodo.7053712.

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<strong>Background:</strong>&nbsp;To assess the performance of the Capintec- CRC-15R dose calibrator which is in use atLiaquat National Hospital (LNH) Karachi, Pakistan for patient dose administration. <strong>Method:</strong>&nbsp;This quantitative study was conducted at Nuclear Medicine department, Liaquat National Hospital,Karachi during the period from July-December 2015. The quality control tests of calibrator were performed using standard sources i.e. Co-57, Ba-133 &amp; CS-137 and data was analyzed for performance assessment of calibrator. <strong>Results:</strong>&nbsp;Capintec CRC-15R
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16

Vásquez, M., E. Huanca, A. Zambrana, and M. ,. Gunnar. "Precisión y exactitud del calibrador de dosis: Capintec crc 12 del laboratorio de radio- farmacia del instituto de medicina nuclear sucre control." Revista de Técnicas de la Enfermería y Salud, June 30, 2020, 1–5. http://dx.doi.org/10.35429/jnt.2020.11.4.1.5.

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The dose calibrator or activity meter is one of the indispensable tools in the laboratories of Radio - pharmacy of a Nuclear Medicine , to measure the activity of the dose of radiopharmaceuticals prior to administration to the patient, so it is important to provide accurate readings, a very high dose would produce unnecessary radiation exposure to the patient or a very low dose , prolong the acquisition time studies affecting the image quality . The aim of the study was to determine the precision and accuracy of dose calibrator or activimeter Lab Radio- pharmacy. In this work, a retrospective
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17

Ghani, Muhammad, Tooba Mujtaba, Kalim Khan, Saeed Rehman, Mohammad Rauf, and Abdur Rehman. "Assessment of molybdenum-99m content in 99Mo/Tc-99m Generator: A clinical audit at Cancer Hospital." Pakistan Journal of Nuclear Medicine, 2024, 1. https://doi.org/10.24911/pjnmed.175-1711777807.

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Nuclear medicine is a branch of medical diagnosis that uses a radioactive tracer to detect the morphological dysfunctions of organs. Nuclear medicine uses Technetitum-99m which is eluted from the Molybdenum Generator. During the elution the technetium from the generators is molybdenum is sometimes eluted with technetium-99m. The content of molybdenum with eluted Technetium-99m may result in compromised image quality and higher patient radiation dose. The measurement of molybdenum content is called the Moly-breakthrough Test (MBT). The study was conducted in Atomic Energy Cancer Hospital, Bannu
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18

Doruyter, A. G. G., and J. L. Holness. "Dual energy window imaging for optimisation of P/V ratios in VP SPECT." EJNMMI Physics 8, no. 1 (2021). http://dx.doi.org/10.1186/s40658-021-00417-z.

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Abstract Purpose Ventilation–perfusion single-photon emission computed tomography (VP SPECT) plays an important role in pulmonary embolism diagnosis. Rapid results may be obtained using same-day ventilation followed by perfusion imaging, but generally requires careful attention to achieving an optimal count rate ratio (P/V ratio) of ≥ 3:1. This study investigated whether the ratio of counts simultaneously acquired in adjacent primary and Compton scatter energy windows (Eratio) on V SPECT was predictive of final normalised perfusion count rate (PCRnorm) on P SPECT using [99mTc]Tc-macroaggregate
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