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Dissertations / Theses on the topic 'Nuclear penetration'

Author: Grafiati

Published: 4 June 2021

Last updated: 3 February 2022

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1

Cohn, Adam R. (Adam Robsohn) 1971. "New technoloogy in a changing electric power sector : market penetration strategies for fuel cells." Thesis, Massachusetts Institute of Technology, 1998. http://hdl.handle.net/1721.1/9614.

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Thesis (S.M.)--Massachusetts Institute of Technology, Dept. of Nuclear Engineering, 1998.<br>Includes bibliographical references.<br>Fuel cells are a promising new technology with the potential to benefit society through high energy conversion efficiencies, low environmental impact, and ability to deliver high quality electricity. After decades of development, the technology is on the verge of commercialization. However, fuel cell penetration of the electric power sector will be inhibited by a number of important market barriers, including high initial costs, lack of awareness, and undemonstra

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2

Qin, Han. "Network fault analysis with increased distributed generation penetration and evaluation of solutions to issues caused by distributed generation." Thesis, University of Warwick, 2017. http://wrap.warwick.ac.uk/99672/.

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Due to concerns of climate change, an increasing number of distributed generation (DG) units have been installed globally in the last two decades. This lead to issues on many aspects in the distribution network operation and management, in which the two most concerned issues are the voltage violation and fault level increase. To regulate the voltage profile and control power flow in the network, power electronic devices based soft open point (SOP) has been developed and trailed in the distribution network according to recent research. These studies mainly focused on the functions and control s

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3

Aydin, Inci, Ruth Villalonga-Planells, Lilo Greune, et al. "A central region in the minor capsid protein of papillomaviruses facilitates viral genome tethering and membrane penetration for mitotic nuclear entry." PUBLIC LIBRARY SCIENCE, 2017. http://hdl.handle.net/10150/624633.

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Incoming papillomaviruses (PVs) depend on mitotic nuclear envelope breakdown to gain initial access to the nucleus for viral transcription and replication. In our previous work, we hypothesized that the minor capsid protein L2 of PVs tethers the incoming vDNA to mitotic chromosomes to direct them into the nascent nuclei. To re-evaluate how dynamic L2 recruitment to cellular chromosomes occurs specifically during prometaphase, we developed a quantitative, microscopy-based assay for measuring the degree of chromosome recruitment of L2-EGFP. Analyzing various HPV16 L2 truncation-mutants revealed

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4

Steinmetz, Fabian. "Integration of data quality, kinetics and mechanistic modelling into toxicological assessment of cosmetic ingredients." Thesis, Liverpool John Moores University, 2016. http://researchonline.ljmu.ac.uk/4522/.

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In our modern society we are exposed to many natural and synthetic chemicals. The assessment of chemicals with regard to human safety is difficult but nevertheless of high importance. Beside clinical studies, which are restricted to potential pharmaceuticals only, most toxicity data relevant for regulatory decision-making are based on in vivo data. Due to the ban on animal testing of cosmetic ingredients in the European Union, alternative approaches, such as in vitro and in silico tests, have become more prevalent. In this thesis existing non-testing approaches (i.e. studies without additional

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5

Kratochvíl, Zdeněk. "Obnova hermetických potrubních průchodek." Master's thesis, Vysoké učení technické v Brně. Fakulta strojního inženýrství, 2017. http://www.nusl.cz/ntk/nusl-318139.

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The topic of this work is the renewal of hermetic pipe penetrations within the primary loop of a nuclear power station. A description of the Dukovany nuclear power plant is included at the beginning, ranging from basic description to details of the renewed component and the reasoning for its replacement. Following is a description of the technologies, which are applied in order to restore the hermetic pipes, the choice of the placement of the heterogeneous weld and the compilation of a workflow for the renewal in the environment of the primary loop while maintaining the quality standards and t

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6

DE, LEON RAFAEL. "Modeling the impact of variable renewable energy sources penetration on supply-demand balance : Analysis of France from 2021 to 2025." Thesis, KTH, Skolan för industriell teknik och management (ITM), 2021. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-294583.

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France is planning a strong development of solar photovoltaics (PV) and wind power in the medium term disrupting the power system. This Master Thesis analyzes the impacts of variable renewable energy production on the supply-demand balance from 2021 to 2025 in France. The model used relies on a dynamic programming method. The analysis is based on the assessment of indicators such as price signals, margins, loss of load duration (LOLD), expected energy not served (EENS) and nuclear drop stop that characterize the supply-demand balance and the security of supply of the electricity system. Wind p

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7

Alam, Tariq Rizvi. "Modeling and Design of Betavoltaic Batteries." Diss., Virginia Tech, 2017. http://hdl.handle.net/10919/89648.

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The betavoltaic battery is a type of micro nuclear battery that harvests beta emitting radioactive decay energy using semiconductors. The literature results suggest that a better model is needed to design a betavoltaic battery. This dissertation creates a comprehensive model that includes all of the important factors that impact betavoltaic battery output and efficiency. Recent advancements in micro electro mechanical systems (MEMS) necessitate an onboard miniaturized power source. As these devices are highly functional, longevity of the power source is also preferred. Betavoltaic batteries

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8

Harby, Mohamed Abd Alaal Khaled. "Experimental and Theoretical Study of the Characteristics of Submerged Horizontal Gas Jets and Vertical Plunging Water Jets in Water Ambient." Doctoral thesis, Universitat Politècnica de València, 2012. http://hdl.handle.net/10251/18065.

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En este estudio se han construido dos diferentes instalaciones para investigar primero los chorros de gas horizontales y en segundo lugar los chorros verticales de agua que impactan sobre superficies libres de fluido, también se ha desarrollado un modelo numérico integral para predecir las trayectorias de estos jets y sus parámetros más importantes, validándose con los resultados experimentales obtenidos. En la primera parte de este trabajo, se han realizado experimentos para investigar el comportamiento de chorros de gas horizontales penetrando en agua. Los resultados experimentales indicaron

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9

Kilk, Kalle. "Cell-penetrating peptides and bioactive cargoes : Strategies and mechanisms." Doctoral thesis, Stockholm : Dept. of Neurochemistry and Neurotoxicology, Univ, 2004. http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-308.

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10

Romero, Hamers Adolfo. "STUDY OF THE THERMAL STRATIFICATION IN PWR REACTORS AND THE PTS (PRESSURIZED THERMAL SHOCK) PHENOMENON." Doctoral thesis, Editorial Universitat Politècnica de València, 2014. http://hdl.handle.net/10251/36536.

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In the event of hypothetical accident scenarios in PWR, emergency strategies have to be mapped out, in order to guarantee the reliable removal of decay heat from the reactor core, also in case of component breakdown. One essential passive heat removal mechanism is the reflux condensation cooling mode. This mode can appear for instance during a small break loss-of-coolant-accident (LOCA) or because of loss of residual heat removal (RHR) system during mid loop operation at plant outage after the reactor shutdown. In the scenario of a loss-of-coolant-accident (LOCA), which is caused by the leak

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11

Sengodan, Anand. "The SIMCA algorithm for processing ground penetrating radar data and its practical applications." Thesis, University of Glasgow, 2013. http://theses.gla.ac.uk/4177/.

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The main objective of this thesis is to present a new image processing technique to improve the detectability of buried objects such as landmines using Ground Penetrating Radar (GPR). The main challenge of GPR based landmine detection is to have an accurate image analysis method that is capable of reducing false alarms. However an accurate image relies on having sufficient spatial resolution in the received signal. An Antipersonnel mine (APM) can have a diameter as little as 2cm, whereas many soils have very high attenuation at frequencies above 450 MHz. In order to solve the detection problem

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12

Srimanee, Artita. "Cell-penetrating peptides targeting glioblastomas for nucleic acid delivery in the blood-brain barrier model." Doctoral thesis, Stockholms universitet, Institutionen för neurokemi, 2017. http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-142109.

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Glioblastoma multiforme is the most aggressive form of malignant brain tumor with poor prognosis. The efficacy of brain cancer treatment by chemotherapeutics is limited by the blood-brain barrier (BBB) which allows less than 2% of the small molecules and blocks almost all the macromolecules to transport into the brain. Delivery of the large molecules such as proteins and nucleic acids across the BBB is a great challenge for brain-targeted drug delivery. To overcome this obstacle, cell-penetrating peptides (CPPs) were used as vectors for delivery of nucleic acids across the BBB targeting gliobl

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13

Guterstam, Peter. "Cell-penetrating peptides, novel synthetic nucleic acids, and regulation of gene function : Reconnaissance for designing functional conjugates." Licentiate thesis, Stockholm : Department of Neurochemistry, Stockholm University, 2008. http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-7491.

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14

Gronewold, Anja [Verfasser], Ines [Gutachter] Neundorf, and Ulrich [Gutachter] Baumann. "Design of cancer-selective and nuclei-targeting cell-penetrating peptides and their characterization / Anja Gronewold ; Gutachter: Ines Neundorf, Ulrich Baumann." Köln : Universitäts- und Stadtbibliothek Köln, 2017. http://d-nb.info/115200493X/34.

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15

Abdul, Fabien. "Développement et évaluation de nouvelles stratégies pour le traitement des hépatites B chroniques, dans le modèle du canard de Pékin infecté par le DHBV." Thesis, Lyon 1, 2010. http://www.theses.fr/2010LYO10284.

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Développement et évaluation de nouvelles stratégies pour le traitement des hépatites B chroniques, dans le modèle du canard de Pékin infecté par le DHBVL’infection chronique par le HBV est la cause majeure de cirrhose hépatique et de carcinome hépatocellulaire, conduisant à plus d’un million de décès chaque année. Le faible taux de réussite des thérapies actuelles des hépatites B montre la nécessité du recours à des méthodes thérapeutiques alternatives. Ainsi, nous avons étudié une stratégie pertinente reposant sur l’utilisation de molécules antisens (PNAs) couplées à des peptides perméabilisa

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16

Cordier, Céline. "Internalisation cellulaire et activité biologique de PNA bloqueurs stériques de la traduction, conjugués au peptide (R/W)9." Phd thesis, Université René Descartes - Paris V, 2014. http://tel.archives-ouvertes.fr/tel-00964872.

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Les Peptide Nucleic Acids (PNA) sont des oligonucléotides antisens analogues de l'ADN, dont le squelette phosphodiester a été remplacé par un squelette pseudo-peptidique d'unités 2-aminoéthylglycine, sur lequel sont greffées des bases azotées. Des PNA dirigés contre les ARN messagers peuvent inhiber la traduction in vitro et dans les cellules humaines. Lorsqu'ils sont dirigés contre la partie codante du transcrit, des PNA polypyrimidiques peuvent bloquer physiquement l'élongation de la traduction en stoppant la machinerie ribosomale. Le transcrit n'est pas dégradé et une protéine tronquée est

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17

Wolf, Justine. "Biophysical investigations of the LAH4 family peptides : enhancer of gene delivery, from peptide-peptide interactions to peptide-membrane interactions." Thesis, Strasbourg, 2018. http://www.theses.fr/2018STRAF037/document.

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Les peptides de la famille du LAH4 sont des peptides cationiques capables de se replier en hélice α amphiphile. Ces peptides sont riches en histidines ce qui permet de moduler les interactions de ces peptides de manière pH dépendante et dans une gamme physiologique. Leurs capacités à interagir et perturber les membranes ont été utilisées pour divers applications biologique, et notamment pour l'amélioration de systèmes de transport de gènes.Le travail de cette thèse a été divisé en trois parties dans le but de caractériser de manière biophysique les différentes interactions ayant lieu lors de l

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18

"Methodology for Identifying Inverter-based Renewable Generation Penetration Threshold in a Power System." Master's thesis, 2020. http://hdl.handle.net/2286/R.I.57141.

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abstract: Energy is one of the wheels on which the modern world runs. Therefore, standards and limits have been devised to maintain the stability and reliability of the power grid. This research shows a simple methodology for increasing the amount of Inverter-based Renewable Generation (IRG), which is also known as Inverter-based Resources (IBR), for that considers the voltage and frequency limits specified by the Western Electricity Coordinating Council (WECC) Transmission Planning (TPL) criteria, and the tie line power flow limits between the area-under-study and its neighbors under continge

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19

"Synthetic molecular evolution of hybrid cell penetrating peptides that efficiently deliver peptide and peptide nucleic acid cargoes to cells." Tulane University, 2017.

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acase@tulane.edu<br>Peptides and peptide nucleic acids (PNAs) have long been recognized as promising tools and potential therapeutics. Yet the cell membrane remains a significant barrier to their intracellular targets. Conjugation to cell penetrating peptides like pTat48-60 (tat) and pAntp43-68 (penetratin) facilitates delivery, however delivery efficiencies remain low. Improving the performance of known cell penetrating peptides by rational design is hindered by the lack of explicit design principles. Instead, here we use synthetic molecular evolution to generate and screen a cell penetrating

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20

Wells, G., Marie Suggitt, M. Coffils, et al. "Fluorescent 7-Diethylaminocoumarin Pyrrolobenzodiazepine conjugates: Synthesis, DNA-Interaction, Cytotoxicity and Differential Cellular Localization." 2008. http://hdl.handle.net/10454/4569.

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no<br>The pyrrolo[2,1-c][1,4]benzodiazepines (PBDs) are a class of DNA minor groove binding agents that react covalently with guanine bases, preferably at Pu-G-Pu sites. A series of three fluorescent PBD¿coumarin conjugates with different linker architectures has been synthesized to probe correlations between DNA binding affinity, cellular localization and cytotoxicity. The results show that the linker structure plays a critical role for all three parameters. Graphical abstract A series of three fluorescent PBD¿coumarin conjugates with different linker architectures has been synthesized to p

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21

(5930420), Lei Xu. "INTERACTIONS OF HIGH VOLTAGE ATMOSPHERIC COLD PLASMA WITH MICROORGANISM AND PROTEIN IN FOOD SYSTEMS." Thesis, 2019.

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<p>Multiple studies have demonstrated atmospheric cold plasma (ACP) as an effective non-thermal technology for microbial decontamination, surface modification, and functionality alteration in food processing and packaging. ACP constitutes charged particles, such as positive and negative ions, electrons, quanta of electromagnetic radiation, and excited and non-excited molecules, which corresponds to its predominant reactive properties. However, in many of these applications, the interactions between plasma and the components in food matrix are not well-understood. The <b>overall goals</b> of th

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22

Lu, Jia Yin, and 盧佳吟. "Nuclear Magnetic Resonance study of heparin enhanced micelle interaction on novel cell-penetrating peptide, ECP32-41." Thesis, 2015. http://ndltd.ncl.edu.tw/handle/60578257833621559532.

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碩士<br>國立清華大學<br>生物資訊與結構生物研究所<br>103<br>Human eosinophil cationic protein (hECP) is a heparin-binding ribonuclease secreted by activated eosinophils. ECP is a basic, granule-stored protein known to be cytotoxic toward pathogens and several cell lines involved in the immune innate system. The mechanism of ECP internalization is including HS binding ability and lipid raft-associated micropinocytosis. Previous studies have discovered that the sequence motif 32NYRWRCKNQN41 of ECP was defined to possess in heparin binding and cell penetrating activities, while motif 32NYRWRCKN39 have been proven to

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23

"Comparing densities in the prehistoric architecture of the Cotzumalguapa Nuclear Zone through the use of ground penetrating radar." CALIFORNIA STATE UNIVERSITY, LONG BEACH, 2010. http://pqdtopen.proquest.com/#viewpdf?dispub=1472233.

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