Academic literature on the topic 'Nuclear periphery'

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Journal articles on the topic "Nuclear periphery"

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Burke, Brian, and Valérie Doye. "The nuclear periphery." Molecular Biology of the Cell 23, no. 6 (2012): 968. http://dx.doi.org/10.1091/mbc.e11-12-0969.

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Garvey Brickner, Donna, and Jason H. Brickner. "Cdk Phosphorylation of a Nucleoporin Controls Localization of Active Genes through the Cell Cycle." Molecular Biology of the Cell 21, no. 19 (2010): 3421–32. http://dx.doi.org/10.1091/mbc.e10-01-0065.

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Many inducible genes in yeast are targeted to the nuclear pore complex when active. We find that the peripheral localization of the INO1 and GAL1 genes is regulated through the cell cycle. Active INO1 and GAL1 localized at the nuclear periphery during G1, became nucleoplasmic during S-phase, and then returned to the nuclear periphery during G2/M. Loss of peripheral targeting followed the initiation of DNA replication and was lost in cells lacking a cyclin-dependent kinase (Cdk) inhibitor. Furthermore, the Cdk1 kinase and two Cdk phosphorylation sites in the nucleoporin Nup1 were required for p
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Hiraga, Shin-ichiro, Sotirios Botsios, David Donze, and Anne D. Donaldson. "TFIIIC localizes budding yeast ETC sites to the nuclear periphery." Molecular Biology of the Cell 23, no. 14 (2012): 2741–54. http://dx.doi.org/10.1091/mbc.e11-04-0365.

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Chromatin function requires specific three-dimensional architectures of chromosomes. We investigated whether Saccharomyces cerevisiae extra TFIIIC (ETC) sites, which bind the TFIIIC transcription factor but do not recruit RNA polymerase III, show specific intranuclear positioning. We show that six of the eight known S. cerevisiae ETC sites localize predominantly at the nuclear periphery, and that ETC sites retain their tethering function when moved to a new chromosomal location. Several lines of evidence indicate that TFIIIC is central to the ETC peripheral localization mechanism. Mutating or
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Tuma, Rabiya S. "Repair at the nuclear periphery." Journal of Cell Biology 172, no. 2 (2006): 164. http://dx.doi.org/10.1083/jcb1722iti1.

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GAMBHIR, Y. K., and A. A. BHAGWAT. "NUCLEON DISTRIBUTIONS AT NUCLEAR PERIPHERY." Modern Physics Letters A 17, no. 19 (2002): 1215–25. http://dx.doi.org/10.1142/s0217732302006278.

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The experimental ratios of the neutron to the proton densities at the nuclear periphery (≃ half-density radius + 2.5 fm) determined using very low energy anti-proton annihilation studies are compared with the predictions of the semi-phenomenological model of the nucleon density distributions. The model incorporates correctly two physical requirements: the correct asymptotic behavior (r → ∞) and the behavior near the center (r → 0). The model gives a good account of the experiment. The results of the more sophisticated, microscopic mean field calculations like non-relativistic Hartree–Fock–Bogo
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Yang, Qiaoxin, Roy Riblet, and Carl L. Schildkraut. "Sites That Direct Nuclear Compartmentalization Are near the 5′ End of the Mouse Immunoglobulin Heavy-Chain Locus." Molecular and Cellular Biology 25, no. 14 (2005): 6021–30. http://dx.doi.org/10.1128/mcb.25.14.6021-6030.2005.

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ABSTRACT VDJ rearrangement in the mouse immunoglobulin heavy chain (Igh) locus involves a combination of events, including a large change in its nuclear compartmentalization. Prior to rearrangement, Igh moves from its default peripheral location near the nuclear envelope to an interior compartment, and after rearrangement it returns to the periphery. To identify any sites in Igh responsible for its association with the periphery, we systematically analyzed the nuclear positions of the Igh locus in mouse non-B- and B-cell lines and, importantly, in primary splenic lipopolysaccharide-stimulated
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Veselsky, Martin, and G. A. Souliotis. "Effect of nuclear periphery on nucleon transfer in peripheral collisions." Nuclear Physics A 765, no. 1-2 (2006): 252–61. http://dx.doi.org/10.1016/j.nuclphysa.2005.11.001.

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Smith, Cheryl L., Andrey Poleshko, and Jonathan A. Epstein. "The nuclear periphery is a scaffold for tissue-specific enhancers." Nucleic Acids Research 49, no. 11 (2021): 6181–95. http://dx.doi.org/10.1093/nar/gkab392.

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Abstract Nuclear architecture influences gene regulation and cell identity by controlling the three-dimensional organization of genes and their distal regulatory sequences, which may be far apart in linear space. The genome is functionally and spatially segregated in the eukaryotic nucleus with transcriptionally active regions in the nuclear interior separated from repressive regions, including those at the nuclear periphery. Here, we describe the identification of a novel type of nuclear peripheral chromatin domain that is enriched for tissue-specific transcriptional enhancers. Like other chr
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Kumaran, R. Ileng, and David L. Spector. "A genetic locus targeted to the nuclear periphery in living cells maintains its transcriptional competence." Journal of Cell Biology 180, no. 1 (2008): 51–65. http://dx.doi.org/10.1083/jcb.200706060.

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The peripheral nuclear lamina, which is largely but not entirely associated with inactive chromatin, is considered to be an important determinant of nuclear structure and gene expression. We present here an inducible system to target a genetic locus to the nuclear lamina in living mammalian cells. Using three-dimensional time-lapse microscopy, we determined that targeting of the locus requires passage through mitosis. Once targeted, the locus remains anchored to the nuclear periphery in interphase as well as in daughter cells after passage through a subsequent mitosis. Upon transcriptional ind
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Trzcińska, A. "Nuclear periphery studied with antiprotonic atoms." Hyperfine Interactions 194, no. 1-3 (2009): 271–76. http://dx.doi.org/10.1007/s10751-009-0078-6.

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Dissertations / Theses on the topic "Nuclear periphery"

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Lemaître, Charlène. "Nuclear architecture and DNA repair : double-strand breaks repair at the nuclear periphery." Thesis, Strasbourg, 2014. http://www.theses.fr/2014STRAJ079/document.

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L'ADN peut être endommagé par des facteurs environnementaux ou intrinsèques au fonctionnement des cellules. Ces facteurs induisent différents types de lésions dont les cassures double brins (CDBs). Les CDBs sont particulièrement dangereuses pour les cellules et une réparation inefficace ou non précise de ces cassures peut entraîner des mutations ou des translocations qui peuvent être à l'origine de cancer. Afin d'éviter l'instabilité génétique que peuvent induire les CDBs, les cellules ont développé deux principaux mécanismes de réparation: la ligature d'extrémités non homologues (NHEJ pour no
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Roman, William. "Positioning nuclei at the periphery of skeletal muscle cells." Thesis, Paris 6, 2016. http://www.theses.fr/2016PA066408/document.

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Les mouvements nucléaires sont importants pour une multitude de fonctions cellulaires et sont induits par des forces produites par des protéines moteurs et le cytosquelette. Lors de la formation et régénération de myofibres, les noyaux migrent du centre à la périphérie de la cellule pour son bon fonctionnement. De plus, certaines maladies musculaires sont caractérisées par une accumulation de noyaux centraux. En utilisant une approche théorique et empirique, nous démontrons que le mouvement de noyaux vers la périphérie des myofibres est induit par des forces centripètes autour des noyaux ainsi
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Goos, Carina [Verfasser], Susanne [Gutachter] Kramer, and Thomas [Gutachter] Dandekar. "Nuclear periphery granules of trypanosomes - A characterization of composition and function / Carina Goos ; Gutachter: Susanne Kramer, Thomas Dandekar." Würzburg : Universität Würzburg, 2021. http://d-nb.info/1232178470/34.

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Détourné, Gwénaëlle. "Characterisation of Nuclear Envelope-Associated Proteins (NEAPs) in Arabidopsis thaliana." Thesis, Université Clermont Auvergne‎ (2017-2020), 2019. http://www.theses.fr/2019CLFAC021/document.

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Au cours de l'évolution, les cellules eucaryotes ont acquis une enveloppe nucléaire (NE) renfermant et protégeant le génome organisé en chromatine, une structure où l'ADN s’enroule autour de protéines histones. La NE est composé de deux membranes : du côté nucléoplasmique, la membrane nucléaire interne (INM) et du côté cytoplasmique, la membrane nucléaire externe. La NE permet la communication entre les deux compartiments par le biais des complexes de pores nucléaires et relie le cytosquelette au nucléosquelette via le complexe LINC (LInker of Nucleoskeleton to Cytoskeleton). Ainsi, le nucléos
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Walther, Tobias. "The role of Peripheral Nuclear Pore Complex (NPC) structures in nuclear transport and NPC architecture." Diss., lmu, 2002. http://nbn-resolving.de/urn:nbn:de:bvb:19-4945.

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Zeng, Yi. "Effect of peripheral wall conduction in pool boiling." Thesis, University of Ottawa (Canada), 1985. http://hdl.handle.net/10393/22397.

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Chodak, Paul. "Destruction of plutonium using non-uranium fuels in pressurized water reactor peripheral assemblies." Thesis, Massachusetts Institute of Technology, 1996. http://hdl.handle.net/1721.1/39999.

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Roman, William [Verfasser]. "Positioning nuclei at the periphery of skeletal muscle cells / William Roman." Berlin : Freie Universität Berlin, 2016. http://d-nb.info/112041024X/34.

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Morton, Paul D. "Nuclear Factor-κB Activation in Schwann Cells Regulates Regeneration and Re-Myelination". Scholarly Repository, 2011. http://scholarlyrepository.miami.edu/oa_dissertations/673.

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Schwann cells (SCs) are crucial for peripheral nerve development and regeneration; however, the intrinsic regulatory mechanisms governing post-injury responses are poorly understood. Activation and deacetylation of nuclear factor-κB (NF- κB) in SCs have been implicated as prerequisites for peripheral nerve myelination. Using GFAP-IκBα-dn mice, in which NF- κB transcriptional activation is inhibited in SCs, we found no discernable differences in the quantity or structure of myelinated axons in adult facial nerves. Following crush injury, axonal regeneration was impaired at 31 days and greatl
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Nuñez, Lautaro. "Complex Formative Settlements in the Central-South Andes: When the Periphery became the Nucleus." Pontificia Universidad Católica del Perú, 2012. http://repositorio.pucp.edu.pe/index/handle/123456789/113341.

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In this paper we discuss the diffusionist implications derived from centre-periphery relationships and the establishment of dependency links between western valley and circunpuna societies within the nuclear zone of the central and southern highlands during the Early and Middle Formative periods in northern Chile (1500 BC up to AD 400). By analyzing two complex settlements, Tulán-54 (located 3000 meters above sea level) and Caserones-1 (900 meters above sea level), we have observed that there has been an over-interpretation of foreign contributions in explaining the rise of sedentism that is a
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Books on the topic "Nuclear periphery"

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Fisch, Adam. Cranial Nerves 5, 7, 9, 10. Oxford University Press, 2013. http://dx.doi.org/10.1093/med/9780199845712.003.0187.

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Rahman, Shamima, and Mirian C. H. Janssen. Disorders of Mitochondrial Energy Metabolism. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199972135.003.0007.

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Mitochondrial disease can be diagnosed at every age, and the clinical presentation is very heterogeneous. In rare cases only a single organ is affected, but multisystem involvement may develop with progression of the disease. Organ systems relying most on aerobic metabolism are preferentially affected, including the central nervous system, peripheral nerves, eye, skeletal and cardiac muscle, and endocrine organs. These disorders can be classified according to whether the causative mutations affect mitochondrial DNA or nuclear DNA. Since specific treatment options are still limited, the managem
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Waldmann, Carl, Neil Soni, and Andrew Rhodes. Death and dying. Oxford University Press, 2011. http://dx.doi.org/10.1093/med/9780199229581.003.0032.

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Confirming death using neurological criteria (brainstem death) 530Withdrawing and withholding treatment 532The potential heart-beating organ donor 534Non-heart-beating organ donation 538The brainstem provides the anatomical link between the spinal cord and cerebral hemispheres relaying sensory and motor impulses between the periphery and higher cortical centres. It also contains cranial nerve nuclei, the reticular activating system and cardiorespiratory control centres, the destruction of which underlies the process of confirming death according to neurological criteria (brainstem death)....
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Nikravan, Sara, and Frederick Mihm. Pathophysiology and management of functional endocrine tumours in the critically ill. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199600830.003.0264.

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Thyroid hormones act on most tissues via nuclear T3 receptors. Thyroid hormones stimulate oxygen consumption and heat production, influence cell growth and maturation (central nervous system, bone), and modulate metabolism (carbohydrates, lipids, proteins, drugs). Treatment for presumed thyroid disease frequently has to be initiated before the results of diagnostic tests are available. Treatment of hyperthyroidism should result in the reduction of serum thyroid hormone levels and their action on peripheral tissues with concurrent treatment of the precipitating event. In severe hypothyroidism t
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Skopeteas, Stavros. Information Structure in Modern Greek. Edited by Caroline Féry and Shinichiro Ishihara. Oxford University Press, 2016. http://dx.doi.org/10.1093/oxfordhb/9780199642670.013.15.

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This chapter deals with the prosodic and syntactic reflexes of information structure in Modern Greek. The relevant properties of this language are: (a) the word order is sensitive to information structure, such that topics and foci target positions in the left periphery and background information is right dislocated; (b) the intonational nucleus depends on the focus domain and is realized through pitch accents; and (b) definite complements must be doubled through co-referent clitic pronouns if they are not accented, which depends on information structure. This chapter introduces these phenomen
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Effects of low-intensity, pain-free exercise on muscle metabolism in patients with peripheral vascular disease evaluated by ³¹P-NMR spectroscopy. 1992.

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Effects of low-intensity, pain-free exercise on muscle metabolism in patients with peripheral vascular disease evaluated by ³¹P-NMR spectroscopy. 1992.

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Effects of low-intensity, pain-free exercise on muscle metabolism in patients with peripheral vascular disease evaluated by ℗đ℗£P-NMR spectroscopy. 1992.

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Effects of low-intensity, pain-free exercise on muscle metabolism in patients with peripheral vascular disease evaluated by p31sP-NMR spectroscopy. 1992.

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Mason, Peggy. Cranial Nerves and Cranial Nerve Nuclei. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780190237493.003.0005.

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The functions of cranial nerves, conduits for sensory information to enter and motor information to exit the brain, and the common complaints arising from cranial nerve injuries are described. The modified anatomical arrangement of sensory and motor territories in the brainstem provides a framework for understanding the organization of the cranial nerve nuclei. A thorough grounding in the anatomy of cranial nerves and cranial nerve nuclei allows the student to deduce whether a given set of symptoms arises from a central or peripheral lesion. The near triad, pupillary light reflex, and Bell’s p
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Book chapters on the topic "Nuclear periphery"

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Trzcińska, A. "Nuclear periphery studied with antiprotonic atoms." In EXA/LEAP 2008. Springer Berlin Heidelberg, 2009. http://dx.doi.org/10.1007/978-3-642-02803-8_90.

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Taddei, Angela, Marc R. Gartenberg, Frank R. Neumann, Florence Hediger, and Susan M. Gasser. "Multiple Pathways Tether Telomeres and Silent Chromatin at the Nuclear Periphery: Functional Implications for Sir-Mediated Repression." In Nuclear Organization in Development and Disease. John Wiley & Sons, Ltd, 2008. http://dx.doi.org/10.1002/0470093765.ch10.

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Lusk, C. Patrick, and Megan C. King. "The Molecular Composition and Function of the Nuclear Periphery and Its Impact on the Genome." In Nuclear Pore Complexes in Genome Organization, Function and Maintenance. Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-71614-5_2.

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Bi, Xiuli, and Chang Liu. "Genome-Wide Identification of Chromatin Domains Anchored at the Nuclear Periphery in Plants." In Methods in Molecular Biology. Springer New York, 2018. http://dx.doi.org/10.1007/978-1-4939-8657-6_23.

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Stewart, Rachel M., Megan C. King, and Valerie Horsley. "Integration of Biochemical and Mechanical Signals at the Nuclear Periphery: Impacts on Skin Development and Disease." In Stem Cell Biology and Regenerative Medicine. Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-16769-5_11.

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Voisin, Maxime, Emmanuel Vanrobays, and Christophe Tatout. "Investigation of Nuclear Periphery Protein Interactions in Plants Using the Membrane Yeast Two-Hybrid (MbY2H) System." In The LINC Complex. Springer New York, 2018. http://dx.doi.org/10.1007/978-1-4939-8691-0_16.

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Robinson, P. J. A., and A. Parkin. "Peripheral vascular disease." In Clinical Nuclear Medicine. Springer US, 1998. http://dx.doi.org/10.1007/978-1-4899-3356-0_15.

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Greyson, N. D. "Peripheral vascular disorders." In Clinical Nuclear Medicine. Springer US, 1991. http://dx.doi.org/10.1007/978-1-4899-3358-4_4.

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Rosenthall, Leonard. "Coagulation and Peripheral Vascular Disease." In Molecular Nuclear Medicine. Springer Berlin Heidelberg, 2003. http://dx.doi.org/10.1007/978-3-642-55539-8_10.

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Xu, Feng. "Nuclear Medicine Imaging in the Diagnosis of Peripheral Lymphedema: Lymphoscintigraphy." In Peripheral Lymphedema. Springer Singapore, 2021. http://dx.doi.org/10.1007/978-981-16-3484-0_19.

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Conference papers on the topic "Nuclear periphery"

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JASTRZȨBSKI, J., A. TRZCIŃSKA, P. LUBIŃSKI, et al. "ANTIPROTONS AND NUCLEAR PERIPHERY." In Proceedings of the Conference “Bologna 2000: Structure of the Nucleus at the Dawn of the Century”. WORLD SCIENTIFIC, 2001. http://dx.doi.org/10.1142/9789812799753_0015.

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Trzcińska, A. "Antiprotonic atoms — a tool for the investigation of the nuclear periphery." In PHYSICS WITH ULTRA SLOW ANTIPROTON BEAMS. AIP, 2005. http://dx.doi.org/10.1063/1.2121984.

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Kawaguchi, Munemichi, Shinya Miyahara, and Masayoshi Uno. "Discussion About Sodium-Concrete Reaction in Presence of Internal Heater." In 2018 26th International Conference on Nuclear Engineering. American Society of Mechanical Engineers, 2018. http://dx.doi.org/10.1115/icone26-82233.

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Sodium-concrete reaction (SCR) is one of the important phenomena during severe accidents in sodium-cooled fast reactors (SFRs) owing to the generation of large sources of hydrogen and aerosols in the containment vessel [1–3]. In this study, SCR experiments were performed to investigate the chemical reaction beneath the internal heater (800 °C), which was used to simulate the obstacle and heating effect for SCR. Furthermore, the effects of the internal heater on the self-termination mechanism were discussed. The internal heater on the concrete seemed to hinder the transport of Na into the concr
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Pecinka, Ladislav, Jaroslav Svoboda, and Vladimír Zeman. "Fretting Wear of the Zr Fuel Rod Cladding." In 2014 22nd International Conference on Nuclear Engineering. American Society of Mechanical Engineers, 2014. http://dx.doi.org/10.1115/icone22-31103.

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Fretting wear is a particular type of wear that is expected to occur in fuel assemblies of pressurized water cooled nuclear reactors. Fretting damage of fuel rods may cause Nuclear Power Plant (NPP) operations problems and are very expensive to repair. As utilities and fuel vendors adopt higher utilization of uranium and improved thermal margins plants, burned fuel rods will be loaded at core the periphery as part of the margin mechanisms. Pressurized Water Reactors (PWRs) have experienced fuel rods fretting wear failures due to flow induced vibrations. This study describes basic results of th
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Zhang, Yunhuang, and Jean C. Ragusa. "Advanced MOX and IMF Fuel Assembly Designs for Multi-Recycling Transuranics." In 18th International Conference on Nuclear Engineering. ASMEDC, 2010. http://dx.doi.org/10.1115/icone18-30153.

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Several new fuel assembly designs for multi-recycling Transuranics from spent nuclear fuel are proposed and investigated. Among these are (1) Mixed Oxide Fuel with Enriched Uranium (MOX-EU), in which Plutonium oxide and U-235 enriched Uranium oxide are mixed (2) MOX fuel with Americium coating, in which a thin layer of Americium is applied to the outer surface of the MOX fuel pellet, and (3) an heterogeneous fuel assembly consists of Inert-Matrix Fuel (IMF) pins at the periphery and UOX pins in the inner zone. All these designs are compatible with standard PWR utilizing 17×17 fuel assemblies.
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Serikov, Arkady. "Shielding Analyses for Gamma Spectrometer GAMMACELL in Experiments on Neutron Generator." In 12th International Conference on Nuclear Engineering. ASMEDC, 2004. http://dx.doi.org/10.1115/icone12-49196.

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The paper is devoted to computational analysis of shielding properties of spectrometer GAMMACELL irradiated by neutrons from 14.1 MeV Neutron Generator (NG). The shielding is required to protect the BaF2 crystals of the gamma spectrometer GAMMACELL from background thermal neutrons, scattered from the walls and equipment in experimental room. GAMMACELL is a scintillation spectrometer of full gamma particles absorption. It consists of 9 BaF2 crystals; each of them has 40×40×100 mm3 dimensions and is viewed by photomultiplier tube. Neutrons also cause flashes in BaF2 crystals and give spurious pu
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Yin, Junlian, Jingjing Li, Hui Chen, Yaoyu Hu, and Dezhong Wang. "Investigation on the Backflow Induced Pre-Rotation of RCP." In 2014 22nd International Conference on Nuclear Engineering. American Society of Mechanical Engineers, 2014. http://dx.doi.org/10.1115/icone22-30896.

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The pre-rotation phenomenon found at the inlet pipe of a pump under small flow rate was observed but the mechanism was not discovered. To do this, an unsteady CFD simulation with the flow rate decreasing from the best design point to a small flow rate was carried out. The numerical results show that a critical point when pre-rotation occurs exists. The flow pattern evolution on the S1 and S2 stream surface, as well as the pressure distribution at in the inlet, was analyzed. It is shown that it is the reverse flow appeared near the shroud at the leading edge which leads to the occurrence of pre
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Chen, Jie, Bingde Chen, and Hong Zhang. "The Research on Scale of Cluster Fuel Assembly Spacer Grids." In 18th International Conference on Nuclear Engineering. ASMEDC, 2010. http://dx.doi.org/10.1115/icone18-29835.

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The existence of boundary walls will impact flow and heat transfer to some extent. The boundary walls decrease the lateral velocities and change the flow direction to form some eddies, so the flow instability increases. Besides, they stop the mass transfer between the inner areas and outside. For the spacer grids of cluster fuel assembly, in order to confirm the scale of simulation object or experiment noumenon, the first thing is to research the influence depth of boundary effect, and try to eliminate its influence to the concerned object or area. This paper is focused on the spacer grids of
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Miyashita, Tohru, Yasuo Koizumi, and Hiroyasu Ohtake. "Rising Velocity of a Gas Plug in Vertical-Rectangular-Narrow Channels." In 18th International Conference on Nuclear Engineering. ASMEDC, 2010. http://dx.doi.org/10.1115/icone18-30235.

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Bubble rising velocity in stagnant water in rectangular channels was examined. The width of the flow channels and the gap space between parallel walls were varied from 10 mm through 150 mm and from 1 mm through 10 mm, respectively. When the bubble had plug shape in the long side and also the short side, the bubble velocity took the same velocity as that in a circular pipe that had the same periphery. When the bubble lost the plug shape in the long side, the rising velocity became fast as the long side shape departed from the plug shape. When the long side was large enough for the bubble to hav
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Li, Xilin, and Ming Jiao. "Sealing Structure Design for Normal Residual Heat Removal Exchanger." In 2017 25th International Conference on Nuclear Engineering. American Society of Mechanical Engineers, 2017. http://dx.doi.org/10.1115/icone25-66424.

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Normal residual heat removal exchanger (RNS HX) is used to remove reactor residual heat during the second stage of reactor shutdown. A hypothetical over-pressurized accident, during which RNS HX would suffer the normal operating pressure and operating temperature of RCS should be considered during the design of RNS HX. This paper introduces Bolt-Flange-Gasket seal structures for RNS HX, considering the leakage-proof during over pressurized situation and some other operating-related aspects. At tube side, Metal-to-metal contact (MMC), with which a mass energy could be stored in metals during bo
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