Academic literature on the topic 'Nucleophilic reactions'

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Journal articles on the topic "Nucleophilic reactions"

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Tsuji, Yutaka, and John P. Richard. "Swain–Scott relationships for nucleophile addition to ring-substituted phenonium ions." Canadian Journal of Chemistry 93, no. 4 (2015): 428–34. http://dx.doi.org/10.1139/cjc-2014-0337.

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The products of the reactions of 2-(4-methoxyphenyl)ethyl tosylate (MeO-1-OTs) and 2-(4-methyphenyl)ethyl tosylate (Me-1-OTs) with nucleophilic anions were determined for reactions in 50:50 (v/v) trifluoroethanol (TFE) / water at 25 °C. In many cases, the nucleophile selectivity kNu/ks ((mol/L)−1) for reactions of nucleophile and solvent, calculated from the ratio of product yields, depends upon [Nu−]. This demonstrates the existence of competing reaction pathways, which show different selectivities for reactions with nucleophiles. A 13C NMR analysis of the products of the reactions of substra
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Selimović, Enisa, and Tanja Soldatović. "Study on the reactions between dichlorido[2,2′:6′,2″-terpyridine] zinc(II) and biologically relevant nucleophiles in aqueous solution." Progress in Reaction Kinetics and Mechanism 44, no. 2 (2019): 105–13. http://dx.doi.org/10.1177/1468678319825724.

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Substitution reactions of square-pyramidal [ZnCl2(terpy)] complex (terpy = 2,2′:6′,2″-terpyridine) with biologically relevant nucleophiles such as imidazole, glutathione, 1,2,4-triazole, and pyrazine were investigated at pH 7.0 as a function of nucleophile concentration. The reactions were followed under pseudo first-order conditions by UV-Vis spectrophotometry. The substitution reactions comprised two steps of consecutive displacement of chlorido ligands. Different reaction pathways for the first reaction step of nucleophilic substitution were defined. The order of reactivity of the investiga
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Vilotijevic, Ivan, Markus Lange, and You Zi. "Latent (Pro)Nucleophiles in Enantioselective Lewis Base Catalyzed Allylic Substitutions." Synlett 31, no. 13 (2020): 1237–43. http://dx.doi.org/10.1055/s-0040-1707130.

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The use of latent nucleophiles, which are molecules that are not nucleophilic but can be activated to act as a nucleophile at an opportune time during the reaction, expands the scope of Lewis base catalyzed reactions. Here, we provide an overview of the concept and show examples of applications to N- and C-centered nucleophiles in allylic substitutions. N- and C-silyl compounds are superior latent (pro)nucleophiles in Lewis base catalyzed reactions with allylic fluorides in which the formation of the strong Si–F bond serves as the driving force for the reactions. The latent (pro)nucleophiles e
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Kimura, Tsutomu. "Recent Advances in Magnesium Carbenoid Chemistry." Synthesis 49, no. 23 (2017): 5105–19. http://dx.doi.org/10.1055/s-0036-1590894.

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Magnesium carbenoids are a class of organomagnesium species possessing a halo group at the α-position. The reactions of magnesium carbenoids can be classified into the following three categories: nucleophilic reactions resembling Grignard reagents, electrophilic reactions resembling organic halides, and rearrangements resembling carbenes. This short review summarizes recent studies on magnesium carbenoids reported between 2010 and 2016, and milestone studies reported before 2010 according to the classification of the reactions into the aforementioned three categories.1 Introduction2 Structures
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Purwono, Bambang, and Estiana R. P. Daruningsih. "NUCLEOPHILIC SUBSTITUTION REACTION OF CYANIDE AND METHOXYDE IONS TO QUATERNARY MANNICH BASE FROM VANILLIN." Indonesian Journal of Chemistry 5, no. 3 (2010): 203–6. http://dx.doi.org/10.22146/ijc.21789.

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The nucleophilic substitution reaction to quaternary Mannich base from vanillin has been investigated. Mannich reaction to vanillin was carried out by refluxing mixture of vanillin, formaldehyde and dimethyl amine. Quaternary ammonium halide salt was obtained from reaction of Mannich vanillin base with methyl iodide in THF solvents and yielded 93.28 %. Nucleophilic substituion to the halide salts with cyanide nucleophile produced 4-hidroxy-3-methoxy-5-(cyano)methylbenzaldehyde in 54.39% yield. Reaction with methoxyde ion yielded 4-hydroxy- 3-methoxy-5-(methoxy) -methylbenzaldehyde in 67.80% yi
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Bosov, Konstantin K., Ekaterina V. Pivovarova, Irina A. Krupnova, Gennady T. Sukhanov, Anna G. Sukhanova, and Yulia V. Filippova. "Alkyl Substituent in Heterocyclic Substrate, Carbon Skeleton Length of O-Nucleophilic Agent and Conditions Influence the Product Composition from Competitive Reactions of SNipso Substitution by Aliphatic Oligoethers." Materials 16, no. 22 (2023): 7068. http://dx.doi.org/10.3390/ma16227068.

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Using 1H NMR spectroscopy, we studied the relative mobility of the NO2 group in 1-alkyl-5-nitro-1,2,4-triazoles in the reaction of nucleophilic heterocyclic substitution by aliphatic oligoethers. The main pathways of the SNipso substitution process and the composition of resultant products from competitive reactions were examined, and the key factors influencing the relative mobility of the nitro group, such as the nitrotriazole substrate constitution, the carbon skeleton length of the O-nucleophilic agent and the process conditions, were discussed. Several independent competitive reactions di
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Undheim, Kjell. "Bond Formation at C8 in the Nucleoside and Nucleotide Purine Scaffold: An Informative Selection." Molecules 29, no. 8 (2024): 1815. http://dx.doi.org/10.3390/molecules29081815.

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This paper presents methods for the introduction and exchange of substituents in a nucleobase and its nucleosides and nucleotides with emphasis on the C8-position in the purine skeleton. The nucleobase is open for electrophilic and nucleophilic chemistry. The nucleophilic chemistry consists mainly of displacement reactions when the C8-substituent is a good leaving group such as a halogen atom. The heteroatom in amines, sulfides, or oxides is a good nucleophile. Halides are good reaction partners. Metal-promoted cross-coupling reactions are important for carbylations. Direct oxidative metalatio
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Imada, Yasushi, Yukihiro Arakawa, Shun Ueta, Takuma Okamoto, and Keiji Minagawa. "Nucleophilic Addition to Nitrones Using a Flow Microreactor." Synlett 31, no. 09 (2020): 866–70. http://dx.doi.org/10.1055/s-0039-1691601.

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Nucleophilic addition reactions of soft carbon nucleophiles to nitrones in a flow microreactor are reported for the first time. Under microflow conditions at 30 to 0 °C, a range of nitrones can be efficiently transformed into the corresponding oxyiminium ions by reaction with either acyl halides or trialkylsilyl triflates. These can subsequently undergo the addition of nucleophiles including allyltributylstannane, ketene methyl tert-butyldimethylsilyl acetal, and N-silyl ketene imines to afford the corresponding adducts in high yields; such reactions at a similar temperature under batch condit
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Kolodiazhnyi, Oleg I. "Stereochemistry of electrophilic and nucleophilic substitutions at phosphorus." Pure and Applied Chemistry 91, no. 1 (2019): 43–57. http://dx.doi.org/10.1515/pac-2018-0807.

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Abstract Nucleophilic and electrophilic substitutions are the most often applied reactions in organophosphorus chemistry. They are closely interrelated, because in a reacting pair always one reagent is an electrophile, and another nucleophile. The reactions of electrophilic and nucleophilic substitutions at the phosphorus center proceed via the formation of a pentacoordinated intermediate. The mechanism of nucleophilic substitution involves the exchange of ligands in the pentacoordinate phosphorane intermediate, leading to the more stable stereomer under the thermodynamic control. Electrophili
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Zhang, Xiao, Guo-ping Lu, and Chun Cai. "Correction: Facile aromatic nucleophilic substitution (SNAr) reactions in ionic liquids: an electrophile–nucleophile dual activation by [Omim]Br for the reaction." Green Chemistry 18, no. 22 (2016): 6143. http://dx.doi.org/10.1039/c6gc90108e.

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Correction for ‘Facile aromatic nucleophilic substitution (S<sub>N</sub>Ar) reactions in ionic liquids: an electrophile–nucleophile dual activation by [Omim]Br for the reaction’ by Xiao Zhang, et al., Green Chem., 2016, 18, 5580–5585.
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Dissertations / Theses on the topic "Nucleophilic reactions"

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Duff, Jack Lawrence. "Single electron transfer in nucleophilic reactions of substituted norbornanes." Thesis, Georgia Institute of Technology, 1989. http://hdl.handle.net/1853/27444.

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Martin, Peter Arnold. "Nucleophilic substitution reactions of some polyhalogenated compounds." Thesis, Durham University, 1987. http://etheses.dur.ac.uk/6876/.

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Rate measurements for the reactions of a series of polyfluoro - and polychloro - pyridines with aniline and ammonia in 60/40 dioxan/water at 25ºC has shown that chlorine, when ortho and para to the position of attack, is activating with respect to fluorine, but at the position meta to the point of attack, chlorine and fluorine are virtually equivalent in their effect on reaction rate. The trifluoromethyl and nitrile groups were found to be activating relative to fluorine when ortho and para to the position of substitution and the nitrile group was thus found to be ortho/para directing. The ort
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Beaumont, Andrew J. "A study of some selective nucleophilic fluorination reactions." Thesis, University of York, 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.306248.

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Jones, Craig Warren. "Nucleophilic aromatic substitution using supported copper(I) reagents." Thesis, University of York, 1989. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.236184.

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Iagrossi, Anna. "Stereochemical studies of reactions of phosphate and thiophosphate esters." Thesis, University of Leicester, 1988. http://hdl.handle.net/2381/33748.

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Nucleophilic substitution reactions involving phosphate monoesters have been investigated. Two general syntheses of O-alkyl or O-aryl [16O,18O] thiophosphate monoesters are reported. An independent and general method for the determination of the enantiomeric excess of isotopically chiral thiophosphate monoesters has been developed and the absolute configurations of the diastereoisomers of (2R)-O-(O-ethyl thiophosphoryl)-3, 4S-dimethyl-5S-phenyl-l,3,2-oxazaphos- pholidin-2-one have been assigned. The solvolysis of p-nitrophenyl [R-16O,18O] thiophosphate in ethanol gives rise to ethyl [16O, 18O]
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Drew, S. M. "Photochemical nucleophilic substitution reactions of quinones and related systems." Thesis, University of Leeds, 1986. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.374182.

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Van, der Westhuizen Carl Johan. "Nucleophilic substitution reactions of α-haloketones : a computational study". Diss., University of Pretoria, 2017. http://hdl.handle.net/2263/63346.

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This dissertation describes the computational modelling of reactions between α-haloketones and various nucleophiles. Nucleophilic substitution reactions of α-haloketones (also known as α- halocarbonyls in literature) are utilised in synthetic laboratories to obtain 1,2-disconnections; which are typically difficult to obtain otherwise. To gain insight into these reactions, DFT modelling was carried out in this project, with further understanding into these reactions being obtained using Quantum Fragment Along Reaction Pathway (QFARP) which is an extension of Interacting Quantum Atoms (IQA
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Baxter, Nicholas James. "The mechanisms of reactions of #beta#-sultams." Thesis, University of Huddersfield, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.285584.

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Liu, Jiangqiong. "Kinetic Studies of 6-Halopurine Nucleoside in SNAr Reactions; 6-(Azolyl, Alkylthio and Fluoro)-purine Nucleosides as Substrates for Suzuki Reactions." Diss., CLICK HERE for online access, 2007. http://contentdm.lib.byu.edu/ETD/image/etd1821.pdf.

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Annandale, Michael Thomas. "NMR spectroscopic studies of nucleophilic attack on dinitroaniline herbicides, reactions of selected nucleophiles with trifluralin and benefin." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1997. http://www.collectionscanada.ca/obj/s4/f2/dsk2/ftp04/mq22268.pdf.

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Books on the topic "Nucleophilic reactions"

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Milton, Harris J., McManus Samuel P, American Chemical Society Meeting, and American Chemical Society. Division of Organic Chemistry., eds. Nucleophilicity. American Chemical Society, 1987.

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Mieczkowski, Józef Bogusław. Zastosowanie reakcji substytucji nukleofilowej do pełnych syntez wybranych alkaloidów i nowych układów heterocyklicznych. Wydawnictwa Uniwersytetu Warszawskiego, 1990.

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Russia) Konferent͡sii͡a Aromaticheskoe nukleofilʹnoe zameshchenie (1989 Novosibirsk. Konferent͡sii͡a Aromaticheskoe nukleofilʹnoe zameshchenie: Tezisy dokladov. Novosibirskiĭ in-t organicheskoĭ khimii SO AN SSSR, 1989.

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Burgers, Martijn Hendrik Willem. Zeolite-catalyzed nucleophilic aromatic substitution reactions =: Nucleofiele aromatische substitutie-reakties gekatalyseerd door metaalhoudende zeolieten. Delft University Press, 1995.

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Burgers, Martijn Hendrik Willem. Zeolite-catalyzed nucleophilic aromatic substitution reactions =: Nucleofiele aromatische substitutie-reakties gekatalyseerd door metaalhoudende zeolieten. Delft University Press, 1995.

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Persson, Jonas. ¹⁸F/¹⁹F and ¹¹C/¹⁴C kinetic isotope effects in nucleophilic substitution reactions. Acta Universitatis Upsaliensis, 1995.

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El-Naby, Sultan Ahmed Abd. A study of the reactions of nucleophiles with [(Indenyl)Fe(CO)2([eta]1-dppa)]BF4 a=m,e,p. University College Dublin, 1997.

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Moore, Patrick A. Synthetic studies of aminoketenes and isocyanatoketenes and nucleophilic reactions of 2,3-bis(trimethylsilyl)-1,3-diene-1,4-dione. National Library of Canada = Bibliothèque nationale du Canada, 1999.

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El-Khomssi, Younis Omar S. Studies of the reactions of nucleophiles with the cycloheptadienyl tetracarbonyl molybdenum cation. University College Dublin, 1997.

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Omar, Abdirahman Hagi Hassan. Reactions of trihalomethyl derivatives of pyridines and pyrimidines with nucleophiles. University of Salford, 1986.

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Book chapters on the topic "Nucleophilic reactions"

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Groutas, William C., and Athri D. Rathnayake. "Nucleophilic Acyl Substitution Reactions." In Organic Reaction Mechanisms, Selected Problems, and Solutions. CRC Press, 2023. http://dx.doi.org/10.1201/9781003390961-16.

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Ross, Sidney D. "Nucleophilic Aromatic Substitution Reactions." In Progress in Physical Organic Chemistry. John Wiley & Sons, Inc., 2007. http://dx.doi.org/10.1002/9780470171806.ch2.

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Ila, Hiriyakkanavar, Anand Acharya, and Saravanan Peruncheralathan. "Domino Reactions Initiated by Nucleophilic Substitution." In Domino Reactions. Wiley-VCH Verlag GmbH & Co. KGaA, 2013. http://dx.doi.org/10.1002/9783527671304.ch4.

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Bäckvall, J. E. "Nucleophilic Attack on Coordinated Alkenes." In Reactions of Coordinated Ligands. Springer US, 1986. http://dx.doi.org/10.1007/978-1-4613-1785-2_11.

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Groutas, William C., and Athri D. Rathnayake. "Nucleophilic Substitution Reactions (SN2) Elimination Reactions (E2)." In Organic Reaction Mechanisms, Selected Problems, and Solutions. CRC Press, 2023. http://dx.doi.org/10.1201/9781003390961-9.

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Went, Charles. "Nucleophilic Reactions of Carbonyl Compounds." In Ionic Organic Mechanisms. Macmillan Education UK, 1986. http://dx.doi.org/10.1007/978-1-349-07964-3_7.

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Afanas'ev, Igor B. "Nucleophilic Reactions of Superoxide Ion." In Superoxide Ion Chemistry and Biological Implications. CRC Press, 2024. https://doi.org/10.1201/9781003574538-6.

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Chambers, R. D., and J. F. S. Vaughan. "Nucleophilic reactions of fluorinated alkenes." In Organofluorine Chemistry. Springer Berlin Heidelberg, 1997. http://dx.doi.org/10.1007/bfb0119264.

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Carey, Francis A., and Richard J. Sundberg. "Alkylation of Nucleophilic Carbon Intermediates." In Part B: Reactions and Synthesis. Springer Berlin Heidelberg, 2001. http://dx.doi.org/10.1007/978-3-662-39510-3_1.

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Åkermark, B., and K. Zetterberg. "π-Allyl Complexes by Nucleophilic Attack." In Inorganic Reactions and Methods. John Wiley & Sons, Inc., 2007. http://dx.doi.org/10.1002/9780470145272.ch21.

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Conference papers on the topic "Nucleophilic reactions"

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Kuznetsov, Yu I. "The Role of Chemical Structure of Organic Compounds in Corrosion Inhibition." In CORROSION 1989. NACE International, 1989. https://doi.org/10.5006/c1989-89134.

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Abstract Some achievements in corrosion inhibition of metals by organic compounds are considered on the basis of analysing the scientific publications during the last decade. The influence of chemical structure of organic compounds on inhibitor protection of various metals dissolving from the active state or undergoing localized corrosion is given special attention. The great importance of considering both the electronic and solvation effects as well as further development of the complex formation concept for better understanding of the inhibition process is emphasized. Attention is drawn to t
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Lyu, Wenyao, and Federico Galvanin. "Automated Identification of Kinetic Models for Nucleophilic Aromatic Substitution Reaction via DoE-SINDy." In The 35th European Symposium on Computer Aided Process Engineering. PSE Press, 2025. https://doi.org/10.69997/sct.107548.

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Nucleophilic aromatic substitutions (SNAr) are key chemical transformations in pharmaceutical and agrochemical synthesis, yet their complex mechanisms (concerted or two-step) complicate kinetic model identification. Accurate kinetic models for SNAr are essential for scale-up, optimization, and control of the reaction process, but conventional methods struggle with mechanism uncertainty driven by substrates, nucleophiles, and reaction conditions, with data collection being difficult due to its source-intensive nature. We address this using DoE-SINDy, a data-driven framework for generative model
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Peixoto, Bárbara Pereira, José Walkimar de M. Carneiro, and Rodolfo Goetze Fiorot. "Substituição nucleofílica alifática: qual o mecanismo preferencial? Estudo computacional dos efeitos da estrutura do substrato e solvente." In VIII Simpósio de Estrutura Eletrônica e Dinâmica Molecular. Universidade de Brasília, 2020. http://dx.doi.org/10.21826/viiiseedmol2020122.

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Nucleophilic aliphatic substitution reactions constitute important steps in the synthesis of substances with biological activity and industrial appeal, beyond to participating in steps in biosynthetic routes of natural products. Unimolecular (SN1) and bimolecular (SN2) pathways can be understood as limiting cases of a mechanistic continuum. In between them, borderline mechanisms are proposed. The preference for one path over another depends on several factors, such as the structure of the substrate, the nucleophile and the solvent used. This plurality is still a topic of discussion and needs f
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Jovanović-Stević, Snežana, Jovana Bogojeski, A. Caković, and B. Petrović. "NUCLEOPHILIC SUBSTITUTION REACTIONS OF THE CAFFEINE- DERIVED PT(II) AND PD(II) COMPLEXES WITH IMPORTANT BIOMOLECULES." In 1st INTERNATIONAL Conference on Chemo and BioInformatics. Institute for Information Technologies, University of Kragujevac, 2021. http://dx.doi.org/10.46793/iccbi21.383js.

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The application of transition metal complexes as chemotherapeutics has been presented throughout the history. Platinum-based drugs are widely used as anticancer agents with a broad range of antitumor activities. The study of the substitution reactions of metal complexes with nitrogen containing biomolecules can help to develop new antitumor drugs with improved characteristics. Kinetics of the substitution reactions of [Pt(caffeine)2Cl2] and [Pd(caffeine)2Cl2] (caffeine = 1,3,7-trimethylxanthine) complexes with biologically important ligands such as 9-methylguanine (9-MetGua) and guanosine-5’-m
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Sucman, Natalia. "Nucleophilic addition of pyridine amines to the double bond of in situ generated morita-baylis-hillman adducts from indole-2,3-dione." In Scientific seminar with international participation "New frontiers in natural product chemistry". Institute of Chemistry, Republic of Moldova, 2023. http://dx.doi.org/10.19261/nfnpc.2023.ab19.

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This report will present the results of addition reactions of indole-2,3-dione to methyl or nitryl acrylate and amino-methyl-pyridine. The addition of an activated alkene like methyl acrylate and nitryl acrylate to a carbon electrophile in the presence of a nucleophilic catalyst is named Morita-Bailys Hillman (MBH) addition. Such adducts are very popular in organic chemistry [1-3]. As a result of screening various substances in search of new catalysts in MBH reactions, substances were discovered that not only catalyzed the addition of olefin to a carbonyl compound but also acted as a reagent t
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Quattrociocchi, Daniel Garcez Santos, Antonio Rafael de Oliveira, Douglas da Motta Pio, and Vinicius Rangel Campos. "Estudo teórico da formação da isatina e de seus derivados dimetoxilados pelo método Sandmeyer." In VIII Simpósio de Estrutura Eletrônica e Dinâmica Molecular. Universidade de Brasília, 2020. http://dx.doi.org/10.21826/viiiseedmol2020109.

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Isatin has been attracted the researchers attention due the structural versatility and can be used to synthesized other molecules with pharmacological activities. The Sandmeyer method is one of the most common methods for the synthesis of this molecule. Where the reaction with from aniline with chloral hydrate and hydroxyl amine occurs with good yield. When the same reaction is performed with dimethoxylated aniline show low yield or is not observed experimentally. These observations motivate this work and the justification for these facts are given in terms of thermodynamic parameters and by t
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Taylor, Grahame, Jonathan Wylde, Walter Samaniego, and Ken Sorbie. "Amorphous Polymeric Dithiazine apDTZ Solid Fouling: Critical Review, Analysis and Solution of an Ongoing Challenge in Triazine-Based Hydrogen Sulphide Mitigation." In SPE International Conference on Oilfield Chemistry. SPE, 2021. http://dx.doi.org/10.2118/204397-ms.

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Abstract Despite attempts to inhibit or avoid the formation of fouling deposits (polymeric amorphous dithiazine or apDTZ for short) from the use of MEA triazine, this remains a major operational problem and limits the use of this most popular and ubiquitous hydrogen sulphide (H2S) scavenger. This paper (a) reviews and summarizes previous work, (b) provides fresh insights into the reaction product and mechanism of formation, (c) proposes an effective method of removal, and (d) proposes some mechanisms of apDTZ digestion. The mechanism of apDTZ formation is discussed and reasoning is provided fr
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Sucman, Natalia. "Diastereoselective synthesis of a novel cyclic derivative based on 2,3-indolinedione." In Scientific seminar with international participation "New frontiers in natural product chemistry". Institute of Chemistry, Republic of Moldova, 2023. http://dx.doi.org/10.19261/nfnpc.2023.ab18.

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Generally, organic synthesis is renowned for its predictability in determining results. Nevertheless, there are situations where instead of the expected products, unexpected compounds with unique structures may arise. This report is a presentation of one such remarkable cyclic compound with four chiral centres prepared by diastereoselective dimerization of Morita-Baylis-Hillman (MBH) adducts of acrylonitrile to 5-chloro-indole-2,3dione. MBH adducts are very popular in organic chemistry. They are synthesized by the addition of an activated alkene and a carbon electrophile in the presence of a n
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Xinglei, Hu. "Experiment and Mechanism Study on the Effect of Coal Ash on the Capture of Alkali Metals in Zhundong Coal." In ASME 2017 Power Conference Joint With ICOPE-17 collocated with the ASME 2017 11th International Conference on Energy Sustainability, the ASME 2017 15th International Conference on Fuel Cell Science, Engineering and Technology, and the ASME 2017 Nuclear Forum. American Society of Mechanical Engineers, 2017. http://dx.doi.org/10.1115/power-icope2017-3570.

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A large number of Xinjiang Zhundong coal was found in China. Its high content of alkali metals can cause serious fouling/slagging problems which may lead to economic losses. It is significant to control the release of alkali metals from Zhundong coal during the combustion. Si-Al additives are used to capture Na released from the Zhundong coal. In this work, a combination of experimental research and quantum chemical calculation was used to study the effect of coal ash on the capture of alkali metal in Zhundong high alkali Coal and the related mineral evolution mechanism during melting processe
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Bastrakov, Maxim, Alexey Starosotnikov, Alexey Fedorenko, and Vladislav Nikol’skyа. "REACTIONS OF NITROPYRIDINES WITH NUCLEOPHILES: SUBSTITUTION, ADDITION, CYCLOADDITION." In Chemistry of nitro compounds and related nitrogen-oxygen systems. LLC MAKS Press, 2019. http://dx.doi.org/10.29003/m744.aks-2019/168-170.

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Reports on the topic "Nucleophilic reactions"

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Cole, Larry L., and John R. Williams. Nucleophilic Displacement Reactions of 4-Substituted-1,2-Dinitrobenzenes with Trialkyl Phosphites. Defense Technical Information Center, 1987. http://dx.doi.org/10.21236/ada185022.

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Borch, Thomas, Yitzhak Hadar, and Tamara Polubesova. Environmental fate of antiepileptic drugs and their metabolites: Biodegradation, complexation, and photodegradation. United States Department of Agriculture, 2012. http://dx.doi.org/10.32747/2012.7597927.bard.

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Abstract:
Many pharmaceutical compounds are active at very low doses, and a portion of them regularly enters municipal sewage systems and wastewater-treatment plants following use, where they often do not fully degrade. Two such compounds, CBZ and LTG, have been detected in wastewater effluents, surface waters, drinking water, and irrigation water, where they pose a risk to the environment and the food supply. These compounds are expected to interact with organic matter in the environment, but little is known about the effect of such interactions on their environmental fate and transport. The original o
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