Relevant bibliographies by topics / Nucleosideos - Metabolismo

Contents

  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters

Academic literature on the topic 'Nucleosideos - Metabolismo'

Author: Grafiati
Published: 4 June 2021
Last updated: 1 February 2022

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the lists of relevant articles, books, theses, conference reports, and other scholarly sources on the topic 'Nucleosideos - Metabolismo.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Journal articles on the topic "Nucleosideos - Metabolismo"

1

Centelles, J. J., M. Cascante, E. I. Canela, and R. Franco. "A model for adenosine transport and metabolism." Biochemical Journal 287, no. 2 (1992): 461–72. http://dx.doi.org/10.1042/bj2870461.

Full text
Abstract:
1. A model is presented for adenosine transport and metabolism in different steady states. The model considers steady-state equations for metabolic enzymes based on information from the literature on their kinetic behaviour. 2. Assuming that extracellular adenosine and inosine are translocated by three transporters, we have devised rate equations for these nucleoside transporters which are valid when both nucleosides are present. Since the Na(+)-independent transporter can either incorporate nucleosides into the cell or release them, various conditions have been simulated in which inosine was
APA, Harvard, Vancouver, ISO, and other styles
2

Dolinar, Klemen, Vid Jan, Mojca Pavlin, Alexander V. Chibalin, and Sergej Pirkmajer. "Nucleosides block AICAR-stimulated activation of AMPK in skeletal muscle and cancer cells." American Journal of Physiology-Cell Physiology 315, no. 6 (2018): C803—C817. http://dx.doi.org/10.1152/ajpcell.00311.2017.

Full text
Abstract:
AMP-activated kinase (AMPK) is a major regulator of energy metabolism and a promising target for development of new treatments for type 2 diabetes and cancer. 5-Aminoimidazole-4-carboxamide-1-β-d-ribofuranoside (AICAR), an adenosine analog, is a standard positive control for AMPK activation in cell-based assays. Some broadly used cell culture media, such as minimal essential medium α (MEMα), contain high concentrations of adenosine and other nucleosides. We determined whether such media alter AICAR action in skeletal muscle and cancer cells. In nucleoside-free media, AICAR stimulated AMPK acti
APA, Harvard, Vancouver, ISO, and other styles
3

Lecoq, K., I. Belloc, C. Desgranges, M. Konrad, and B. Daignan-Fornier. "YLR209c Encodes Saccharomyces cerevisiae Purine Nucleoside Phosphorylase." Journal of Bacteriology 183, no. 16 (2001): 4910–13. http://dx.doi.org/10.1128/jb.183.16.4910-4913.2001.

Full text
Abstract:
ABSTRACT The yeast YLR209c (PNP1) gene encodes a protein highly similar to purine nucleoside phosphorylases. This protein specifically metabolized inosine and guanosine. Disruption ofPNP1 led to inosine and guanosine excretion in the medium, thus showing that PNP1 plays an important role in the metabolism of these purine nucleosides in vivo.
APA, Harvard, Vancouver, ISO, and other styles
4

Pogosian, L. H., L. S. Nersesova, M. G. Gazariants, Z. S. Mkrtchian, and J. I. Akopian. "Some inhibitors of purine nucleoside phosphorylase." Biomeditsinskaya Khimiya 57, no. 5 (2011): 526–34. http://dx.doi.org/10.18097/pbmc20115705526.

Full text
Abstract:
Purine nucleoside phosphorylase (PNP) catalyzes reversible phosphorolysis of purine deoxy- and ribonucleosides with formation (d)Rib-1-P and corresponding bases. PNP plays a leading role in the cell metabolism of nucleosides and nucleotides, as well as in maintaining the immune status of an organism. The major aim of the majority of studies on the PNP is the detection of highly effective inhibitors of this enzyme, derivatives of purine nucleosides used in medicine as immunosuppressors, which are essential for creating selective T-cell immunodeficiency in a human body for organ and tissue trans
APA, Harvard, Vancouver, ISO, and other styles
5

Kawczyński, W., B. Czochralska, and D. Shugar. "Electrochemical reduction products of azido nucleosides, including zidovudine (AZT): mechanisms and relevance to their intracellular metabolism." Acta Biochimica Polonica 40, no. 2 (1993): 213–23. http://dx.doi.org/10.18388/abp.1993_4821.

Full text
Abstract:
Previous studies on electrochemical reduction of the HIV reverse transcriptase inhibitor, 3'-azido-3'-deoxythymidine (Zidovudine, AZT) and several of its analogues, have been extended to 2'-AZdT and two of the intracellular metabolites of AZT, the 5'-O-glucuronide (GAZT) and the 5'-phosphate (AZTMP). Also investigated were azido nucleosides with aglycons susceptible to electrochemical reduction, cytosine and adenine. The surface activities of these compounds at the mercury electrode were examined. In all instances, reduction of the azido group was a two-electron process, with conversion to an
APA, Harvard, Vancouver, ISO, and other styles
6

Aučynaitė, Agota, Rasa Rutkienė, Daiva Tauraitė, Rolandas Meškys, and Jaunius Urbonavičius. "Identification of a 2′-O-Methyluridine Nucleoside Hydrolase Using the Metagenomic Libraries." Molecules 23, no. 11 (2018): 2904. http://dx.doi.org/10.3390/molecules23112904.

Full text
Abstract:
Ribose methylation is among the most ubiquitous modifications found in RNA. 2′-O-methyluridine is found in rRNA, snRNA, snoRNA and tRNA of Archaea, Bacteria, and Eukaryota. Moreover, 2′-O-methylribonucleosides are promising starting materials for the production of nucleic acid-based drugs. Despite the countless possibilities of practical use for the metabolic enzymes associated with methylated nucleosides, there are very few reports regarding the metabolic fate and enzymes involved in the metabolism of 2′-O-alkyl nucleosides. The presented work focuses on the cellular degradation of 2′-O-methy
APA, Harvard, Vancouver, ISO, and other styles
7

Fisher, Owain, Ruth A. Benson, and Christopher HE Imray. "The clinical application of purine nucleosides as biomarkers of tissue Ischemia and hypoxia in humans in vivo." Biomarkers in Medicine 13, no. 11 (2019): 953–64. http://dx.doi.org/10.2217/bmm-2019-0049.

Full text
Abstract:
During periods of ischemia and hypoxia, intracellular adenosine triphosphate stores are rapidly depleted. Its metabolism results in release of purine nucleosides into the systemic circulation. While the potential of purine nucleosides as a biomarker of ischemia has long been recognized, this has been limited by their complex physiological role and inherent instability leading to problematic sampling and prolonged, complex analysis procedures. Purine release has been demonstrated from cerebral tissue in patients undergoing carotid endarterectomy and patients presenting to hospital with stroke a
APA, Harvard, Vancouver, ISO, and other styles
8

WORMIT, Alexandra, Michaela TRAUB, Martin FLÖRCHINGER, H. Ekkehard NEUHAUS, and Torsten MÖHLMANN. "Characterization of three novel members of the Arabidopsis thaliana equilibrative nucleoside transporter (ENT) family." Biochemical Journal 383, no. 1 (2004): 19–26. http://dx.doi.org/10.1042/bj20040389.

Full text
Abstract:
Research on metabolism of nucleotides and their derivatives has gained increasing interest in the recent past. This includes de novo synthesis, analysis of salvage pathways, breakdown and transport of nucleotides, nucleosides and nucleobases. To perform a further step towards the analysis of nucleoside transport in Arabidopsis, we incubated leaf discs with various radioactively labelled nucleosides. Leaf cells imported labelled nucleosides and incorporated these compounds into RNA, but not into DNA. Furthermore, we report on the biochemical properties of three so far uncharacterized members of
APA, Harvard, Vancouver, ISO, and other styles
9

Griffon, Jean-François, Sue C. Shaddix, William B. Parker та ін. "Synthesis and Biological Evaluation of Some 4'-C-(Hydroxymethyl)-α- and -β-D-Arabinofuranosyl Pyrimidine and Adenine Nucleosides". Collection of Czechoslovak Chemical Communications 71, № 7 (2006): 1063–87. http://dx.doi.org/10.1135/cccc20061063.

Full text
Abstract:
A series of 4'-C-(hydroxymethyl) analogs of pyrimidine and purine nucleosides have been prepared utilizing standard methodologies, and the α and β anomers were separated. These analogs are part of our continuing efforts to identify new anticancer drugs as well as to explore the substrate specificities of these analogs with the initial activating enzymes in the metabolic pathway leading to nucleoside triphosphates. Although not cytotoxic to CCRF-CEM cells (an acute lymphoblastic leukemia of T-cell origin), many of these compounds were utilized as substrates for the various human nucleoside kina
APA, Harvard, Vancouver, ISO, and other styles
10

Young, J. D., S. M. Jarvis, A. S. Clanachan, J. F. Henderson, and A. R. Paterson. "Nitrobenzylthioinosine: an in vivo inhibitor of pig erythrocyte energy metabolism." American Journal of Physiology-Cell Physiology 251, no. 1 (1986): C90—C94. http://dx.doi.org/10.1152/ajpcell.1986.251.1.c90.

Full text
Abstract:
The potential role of plasma nucleosides as metabolic energy substrates for pig erythrocytes, which are impermeable to glucose, was investigated in vivo by infusion of anesthetized pigs with nitrobenzylthioinosine phosphate (NBMPR-P), a soluble prodrug form of the specific nucleoside transport inhibitor, nitrobenzylthioinosine. NBMPR-P administration (1 or 10 mg X kg-1 X h-1) led to complete in vivo blockade of erythrocyte nucleoside transport activity and was associated with a dramatic decrease in the erythrocyte [ATP]-to-[ADP] ratio from 11.4 at time 0 to 2.9 after 4 h (mean results from 3 a
APA, Harvard, Vancouver, ISO, and other styles
More sources

Dissertations / Theses on the topic "Nucleosideos - Metabolismo"

1

Saraiva, Antonio Marcos. "Caracterização funcional e estrutural da nucleotidase SurE de Xyllela fastidiosa." [s.n.], 2009. http://repositorio.unicamp.br/jspui/handle/REPOSIP/316474.

Full text
Abstract:
Orientador: Anete Pereira de Souza<br>Tese (doutorado) - Universidade Estadual de Campinas, Instituto de Biologia<br>Made available in DSpace on 2018-08-14T21:21:36Z (GMT). No. of bitstreams: 1 Saraiva_AntonioMarcos_D.pdf: 12032714 bytes, checksum: 1262a05ca10735e855fa138a2093d04b (MD5) Previous issue date: 2009<br>Resumo: A linhagem 9a5c da bactéria Xylella fastidiosa foi o primeiro fitopatógeno a ter seu genoma completamente sequenciado, o qual gerdu diversas informações sobre seu metabolismo e patogenicidade. Das orfs codificadas por esta bactéria, destaca-se; no presente trabalho, a XF07
APA, Harvard, Vancouver, ISO, and other styles
2

Andrade, Claudia Marlise Balbinotti. "Estudo das ectonucleotidases em células estreladas hepáticas : relação entre a expressão, atividade e significado fisiológico." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2008. http://hdl.handle.net/10183/15499.

Full text
Abstract:
As células estreladas hepáticas (HSCs) são a principal fonte de componentes de matriz extracelular em doenças crônicas do fígado e, por esta razão, exercem um papel fundamental no desenvolvimento e na manutenção da fibrose hepática. Os nucleotídeos e nucleosídeos são moléculas sinalizadoras que regulam diversos processos no fígado e têm um importante papel na patogênese da fibrose hepática. As ecto-nucleosídeo trifosfato difosfoidrolases (E-NTPDases), ecto-nucleotídeo pirofosfatase fosfodiesterases (E-NPPs), ecto-5’-nucleotidase (eNT/CD73) e a fosfatase alcalina tecido inespecífica (TNALP) são
APA, Harvard, Vancouver, ISO, and other styles
3

Cabrera, Pérez Raquel. "Terapia génica para el MNGIE: Estudio comparativo de diferentes vectores adeno-asociados en el modelo preclínico de la enfermedad." Doctoral thesis, Universitat Autònoma de Barcelona, 2017. http://hdl.handle.net/10803/458540.

Full text
Abstract:
El MNGIE (encefalomiopatía neurogastrointestinal mitocondrial) es una enfermedad rara de herencia autosómica recesiva que provoca afectación de la función muscular, neuronal y gastrointestinal y cuya esperanza de vida se sitúa en torno a los 37 años. Está causada por mutaciones en el gen nuclear TYMP, que codifica la timidina fosforilasa (TP). La TP cataliza el primer paso del catabolismo de los nucleósidos timidina (dThd) y desoxiuridina (dUrd), por lo que disfunciones en esta enzima provocan la acumulación sistémica de estos nucleósidos. La sobrecarga de dThd y dUrd da lugar a un exceso de d
APA, Harvard, Vancouver, ISO, and other styles
4

Scott, Allelia Worrall. "Pyrimidine Nucleoside Metabolism in Pseudomonads and Enteric Bacteria." Thesis, University of North Texas, 1991. https://digital.library.unt.edu/ark:/67531/metadc500941/.

Full text
Abstract:
Metabolic differences in the strategies used for pyrimidine base and nucleoside salvage were studied in the pseudomonads and enteric bacteria. Fluoro--analogs were used to select mutant strains of E. coli, S. typhimurium, P. putida, and P. aeruginosa blocked in one or more of the uracil and uridine salvage enzymes. HPLC analysis of cell-free extracts from wild-type and mutant strains examined the effectiveness of the selections. Evidence was found for cytidine kinase in Pseudomonas and for an activity that converted uracil compounds to cytosine compounds. Using media supplemented with 150 μg o
APA, Harvard, Vancouver, ISO, and other styles
5

Cummins, Jane H. "Stereochemical studies in mechanistic enzymology using nucleoside phosphorothioates." Thesis, University of Leicester, 1990. http://hdl.handle.net/2381/34071.

Full text
Abstract:
A simple method for the configurational analysis of the four major 2'-deoxynucleoside 5'-[160, 180] phosphorothioates, (1), and adenosine 5'-[160, 180] phosphorothioate, (1a), is described. The method involves permethylation of (1,1a) with diazomethane or dimethyl sulphate, to generate the corresponding S-methyl-O-methyl phosphorothioate, (2,2a), 8P(3:1 DMF:d4-MeOH) +30ppm. Having assigned the diastereoisomers of (2,2a) to their corresponding 31P.n.m.r. resonances, the 18O-isotope is located by examination of 31P(180) isotope shifts. A larger shift, (0.05ppm), is observed on the diastereoisome
APA, Harvard, Vancouver, ISO, and other styles
6

Borg, Natalia. "Distribution of antiviral nucleoside analogues to brain and skin /." Stockholm, 1999. http://diss.kib.ki.se/1999/91-628-3202-6/.

Full text
APA, Harvard, Vancouver, ISO, and other styles
7

Lee, Yick-Shun. "Pyrimidine Metabolism in Bacteria: Physiological Properties of Nucleoside Hydrolase and Uridine Kinase." Thesis, University of North Texas, 1991. https://digital.library.unt.edu/ark:/67531/metadc798309/.

Full text
APA, Harvard, Vancouver, ISO, and other styles
8

Stow, Ruth Anne. "Purine nucleoside transport and metabolism across the rat small intestine." Thesis, University of York, 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.258382.

Full text
APA, Harvard, Vancouver, ISO, and other styles
9

Vodnala, Munender. "Targeting the nucleotide metabolism of the mammalian pathogen Trypanosoma brucei." Doctoral thesis, Umeå universitet, Institutionen för medicinsk kemi och biofysik, 2013. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-80904.

Full text
Abstract:
Trypanosoma brucei causes African sleeping sickness in humans and Nagana in cattle. There are no vaccines available against the disease and the current treatment is also not satisfactory because of inefficacy and numerous side effects of the used drugs. T. brucei lacks de novo synthesis of purine nucleosides; hence it depends on the host to make its purine nucleotides. T. brucei has a high affinity adenosine kinase (TbAK), which phosphorylates adenosine, deoxyadenosine (dAdo), inosine and their analogs. RNAi experiments confirmed that TbAK is responsible for the salvage of dAdo and the toxicit
APA, Harvard, Vancouver, ISO, and other styles
10

Månsson, Emma. "Resistance mechanisms for nucleoside analogues - with focus on metabolism and apoptosis /." Stockholm : [Karolinska institutets bibl.], 2002. http://diss.kib.ki.se/2002/91-7349-330-9/.

Full text
APA, Harvard, Vancouver, ISO, and other styles
More sources

Books on the topic "Nucleosideos - Metabolismo"

1

S, Bruzik K., and Stec W. J, eds. Biophosphates and their analogues: Synthesis, structure, metabolism, and activity : proceedings of the 2nd International Symposium on Phosphorus Chemistry Directed Towards Biology, Łodz, Poland, 8-12 September 1986. Elsevier, 1987.

Find full text
APA, Harvard, Vancouver, ISO, and other styles
2

1945-, Richter Ch, ed. ADP-ribosylation of proteins: Enzymology and biological significance. Springer-Verlag, 1987.

Find full text
APA, Harvard, Vancouver, ISO, and other styles
3

W, Gehrke Charles, and Kuo, Kenneth C. T., 1936-, eds. Chromatography and modification of nucleosides. Elsevier, 1990.

Find full text
APA, Harvard, Vancouver, ISO, and other styles
4

Gehrke, Charles W., and Kenneth C. T. Kuo. Modified Nucleosides in Cancer and Normal Metabolism - Methods and Applications. Elsevier Science & Technology Books, 1990.

Find full text
APA, Harvard, Vancouver, ISO, and other styles
5

Chromatography and Modification of Nucleosides - Modified Nucleosides in Cancer and Normal Metabolism Methods and Applications. Elsevier, 1990. http://dx.doi.org/10.1016/s0301-4770(08)x6070-1.

Full text
APA, Harvard, Vancouver, ISO, and other styles
6

Gehrke, Charles W., and Kenneth C. T. Kuo. Chromatography and Modification of Nucleosides, Part A: Analytical Methods for Major and Modified Nucleosides Hplc, Gc, Ms, Nmr, Uv and Ft-Ir (Journal of Chromatography Library). Elsevier Publishing Company, 1990.

Find full text
APA, Harvard, Vancouver, ISO, and other styles
7

F, Eccleston J., and Royal Society (Great Britain), eds. Nucleoside triphosphatases in energy transduction, cellular regulation and information transfer in biological systems: A discussion meeting of the Royal Society. Portland Press, 1992.

Find full text
APA, Harvard, Vancouver, ISO, and other styles
8

Gehrke, Charles W. Chromatography And Modification Of Nucleosides Pt.c (Developmental Clinical Psychology and Psychiatry (Cloth)). Edited by Charles Gehrke. Elsevier Science Publishing Company, 1990.

Find full text
APA, Harvard, Vancouver, ISO, and other styles
9

Althaus, Felix R. ADP-Ribosylation of Proteins: Enzymology and Biological Significance. Springer, 2012.

Find full text
APA, Harvard, Vancouver, ISO, and other styles
10

Althaus, Felix R. Adp-Ribosylation of Proteins. Springer, 2013.

Find full text
APA, Harvard, Vancouver, ISO, and other styles

Book chapters on the topic "Nucleosideos - Metabolismo"

1

Ray, Adrian S., and Michael J. M. Hitchcock. "Metabolism of Antiviral Nucleosides and Nucleotides." In Antiviral Research. ASM Press, 2014. http://dx.doi.org/10.1128/9781555815493.ch17.

Full text
APA, Harvard, Vancouver, ISO, and other styles
2

Zhen, Yong-Su, Jian Su, Yu-Chuan Xue, Chang-Qing Qi, and Ji-Lan Hu. "Novel Nucleoside Transport Inhibitors of Natural Origin." In Purine and Pyrimidine Metabolism in Man VIII. Springer US, 1995. http://dx.doi.org/10.1007/978-1-4615-2584-4_163.

Full text
APA, Harvard, Vancouver, ISO, and other styles
3

Bronk, J. R., P. A. Helliwell, and Ruth A. Stow. "Intestinal Transport and Metabolism of Purine and Pyrimidine Nucleosides." In Advances in Experimental Medicine and Biology. Springer US, 1991. http://dx.doi.org/10.1007/978-1-4899-2638-8_92.

Full text
APA, Harvard, Vancouver, ISO, and other styles
4

Cohn, Major L., Faye A. Eggerding, Antonio F. Machado, Stephan J. Cohn, Bart D. Waxman, and Timothy Delaney. "Morphine: Sites of Action in Guanosine Nucleoside Pathway." In Purine and Pyrimidine Metabolism in Man V. Springer US, 1986. http://dx.doi.org/10.1007/978-1-4684-1248-2_8.

Full text
APA, Harvard, Vancouver, ISO, and other styles
5

Gilbertsen, Richard B., and Mi K. Dong. "Blockade of Nucleoside Degradation in Monkey Whole Blood in Vitro by CI-1000, a Purine Nucleoside Phosphorylase (PNP) Inhibitor." In Purine and Pyrimidine Metabolism in Man VIII. Springer US, 1995. http://dx.doi.org/10.1007/978-1-4615-2584-4_37.

Full text
APA, Harvard, Vancouver, ISO, and other styles
6

Abd-Elfattah, Anwar-Saad A., Jeff Hoehner, and Andrew S. Wechsler. "Identification of nucleoside transport binding sites in the human myocardium." In Cardiac Metabolism in Health and Disease. Springer US, 1998. http://dx.doi.org/10.1007/978-1-4615-5687-9_11.

Full text
APA, Harvard, Vancouver, ISO, and other styles
7

Tozzi, M. G., M. Camici, R. Pesi, et al. "Regulation of Calf Thymus Cytosolic 5’-Nucleotidase/Nucleoside Phosphotransferase." In Purine and Pyrimidine Metabolism in Man VIII. Springer US, 1995. http://dx.doi.org/10.1007/978-1-4615-2584-4_120.

Full text
APA, Harvard, Vancouver, ISO, and other styles
8

Véron, Michel, Annemiek Tepper, Martin Hildebrandt, et al. "Nucleoside Diphosphate Kinase: an Old Enzyme with New Functions?" In Purine and Pyrimidine Metabolism in Man VIII. Springer US, 1995. http://dx.doi.org/10.1007/978-1-4615-2584-4_126.

Full text
APA, Harvard, Vancouver, ISO, and other styles
9

Aronow, Bruce, and Buddy Ullman. "Mutant Mouse Cells with Nitrobenzylthioinosine-Insensitive Nucleoside Transport Functions." In Purine and Pyrimidine Metabolism in Man V. Springer US, 1986. http://dx.doi.org/10.1007/978-1-4684-1248-2_13.

Full text
APA, Harvard, Vancouver, ISO, and other styles
10

Gero, Annette M., and Joanne M. Upston. "Altered Purine Nucleoside Transport as a Target for Malaria Chemotherapy." In Purine and Pyrimidine Metabolism in Man VIII. Springer US, 1995. http://dx.doi.org/10.1007/978-1-4615-2584-4_104.

Full text
APA, Harvard, Vancouver, ISO, and other styles
You might also be interested in the extended bibliographies on the topic 'Nucleosideos - Metabolismo' for particular source types:
Journal articles Dissertations / Theses
We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!

To the bibliography