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Dissertations / Theses on the topic 'Number of glial cells'

Author: Grafiati

Published: 4 June 2021

Last updated: 12 February 2022

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1

Förster, Bettina Ulrike. "Talin in glial cells." Thesis, University of Cambridge, 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.612772.

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2

Schuliga, Michael, and michael schuliga@deakin edu au. "Steroidogenesis in cultured mammalian glial cells." Deakin University. School of Biological and Chemical Sciences, 1998. http://tux.lib.deakin.edu.au./adt-VDU/public/adt-VDU20061207.154152.

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A protocol for culturing mammalian type 1 astrocytic cells, using female post-natal rat cerebral cortical tissue, was established and refined for use in steroidogenic metabolic studies incorporating progestin radioisotopes. Cultures were characterised for homogeneity using standard morphological and immunostaining techniques. Qualitative and quantitative studies were conducted to characterise the progesterone (P) metabolic pathways present in astrocytes in vitro. Of particular interest was the formation of the P metabolite, 5á-pregnan-3á-ol-20-one (THP). THP is a GABA(A) receptor agonist,

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3

Mellor, Robert. "Neurochemical studies on cultured glial cells." Thesis, University of Oxford, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.300038.

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4

Nutt, Catherine L. "Mechanisms of drug resistance in glial cells." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1997. http://www.collectionscanada.ca/obj/s4/f2/dsk3/ftp04/nq28512.pdf.

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5

Nieweg, Katja Pfrieger Frank. "Cholesterol biosynthesis in neurons and glial cells." Strasbourg : Université de Strasbourg, 2009. http://eprints-scd-ulp.u-strasbg.fr:8080/1048/01/NIEWEG_Katja_2007.pdf.

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6

Nieweg, Katja. "Cholesterol biosynthesis in neurons and glial cells." Université Louis Pasteur (Strasbourg) (1971-2008), 2007. https://publication-theses.unistra.fr/public/theses_doctorat/2007/NIEWEG_Katja_2007.pdf.

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Cette étude confirme l’hypothèse d’une dépendance des neurones en cholesterol astrocytaire au stade postnatal. Nos travaux montrent que les neurones ne peuvent assurer leurs besoins en cholestérol: L’accumulation de lanostérol et la lente conversion de stérols intermédiaires indiquent que les neurones produisent du cholesterol de façon moins efficace que les cellules gliales. La diminution le taux de cholestérol dans les neurones n’induit pas d’augmentation de l’expression des enzymes de sa voie de biosynthèse. L’absence de synthèse d’ester de cholesterol et d’organelles de stockage de cholest

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7

Gao, Yuanqing. "Hypothalamic Glial Cells in Diet Induced Obesity." University of Cincinnati / OhioLINK, 2015. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1447071648.

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8

Burne, Julia Fiona. "The role of retinal ganglion cell axions in the regulation of glial cell numbers in the rodent optic nerve." Thesis, University College London (University of London), 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.264697.

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9

Cotterill, Claire Louise. "Semliki Forest virus-induced apoptosis in glial cells." Thesis, University of Edinburgh, 2005. http://hdl.handle.net/1842/29712.

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Multiple sclerosis (MS) is the most common neurological disease affecting young adults. The incidence rates in Scotland are among the highest in the world. Virus infection may have a precipitating role, or exacerbate symptoms. That viruses can produce inflammatory central nervous system (CNS) demyelinating disease has been well established from study of several natural and experimental infections; one model system is Semliki Forest virus (SFV) infection of mice. SFV infection of BALB/c mice infected at less than 12 days of age (P12) causes fulminant encephalitis, characterised by apoptotic dea

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10

Göritz, Christian. "Influence of glial cells on postnatal differentiation of rat retinal ganglion cells." [S.l. : s.n.], 2005. http://www.diss.fu-berlin.de/2005/65/index.html.

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11

Göritz, Christian. "Influence of glial cells on postnatal differentiation of rat retinal ganglion cells." Université Louis Pasteur (Strasbourg) (1971-2008), 2005. https://publication-theses.unistra.fr/public/theses_doctorat/2005/GORITZ_Christian_2005.pdf.

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12

Rabah, Yasmine. "Satellite glial cell-proprioceptor interactions in dorsal root ganglia Characterization of transgenic mouse lines for selectively targeting glial cells in dorsal root ganglia Satellite glial cells modulate proprioceptive neuron function." Thesis, Sorbonne Paris Cité, 2018. http://www.theses.fr/2018USPCB208.

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Les neurones propriocepteurs sont nécessaires au contrôle du mouvement et à la locomotion. Ils connectent les fuseaux musculaires et les tendons aux motoneurones de la moelle épinière pour informer le système nerveux central de l’état d’élongation et de contraction des muscles. Leurs corps cellulaires sont localisés dans les ganglions rachidiens dorsaux (GRD), où ils sont intimement entourés de cellules gliales GFAP-positives appelées cellules satellites gliales (CSG). Comme les astrocytes du système nerveux central, les CSG expriment à leur surface des récepteurs couplés aux prote

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13

Blackburn, Daniel J. "The role of glial cells in motor neuron disease." Thesis, University of Sheffield, 2011. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.531123.

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14

Acton, David. "Regulation of mammalian spinal locomotor networks by glial cells." Thesis, University of St Andrews, 2017. http://hdl.handle.net/10023/10133.

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Networks of interneurons within the spinal cord coordinate the rhythmic activation of muscles during locomotion. These networks are subject to extensive neuromodulation, ensuring appropriate behavioural output. Astrocytes are proposed to detect neuronal activity via Gαq-linked G-protein coupled receptors and to secrete neuromodulators in response. However, there is currently a paucity of evidence that astrocytic information processing of this kind is important in behaviour. Here, it is shown that protease-activated receptor-1 (PAR1), a Gαq-linked receptor, is preferentially expressed by glia i

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15

Sinclair, Michael S. "Modulation of Peripheral Taste Function by Glial-like Taste Cells." Scholarly Repository, 2012. http://scholarlyrepository.miami.edu/oa_dissertations/715.

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Taste is detected by cells of taste buds in the oral cavity. Mammalian taste buds contain three types of cells: receptor, presynaptic, and glial-like. Of these three, glial-like cells are the least studied. Their only known function is that they clear neurotransmitters from the extracellular space. The present work describes two previously undocumented properties of glial-like cells. First, Oxytocin receptor (OXTR) mRNA was detected by RT-PCR in taste tissue of mice. In the taste buds of Oxtr-YFP knockin mice, YFP was seen in glial-like taste cells and other cells immediately outside the

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16

Köritzer, Julia. "Biophysical effects of cold atmopheric plasma on glial tumor cells." Diss., Ludwig-Maximilians-Universität München, 2013. http://nbn-resolving.de/urn:nbn:de:bvb:19-162120.

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17

Keen, Leigh John. "The growth and pharmacology of insect glial cells in vitro." Thesis, Oxford Brookes University, 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.359837.

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18

Smith, Peter Michael. "Investigations into the myelinating capability of transplanted porcine glial cells." Thesis, University of Cambridge, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.624554.

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19

Stuckey, Crystal Elaine. "Oxidative Stress and Cell Death in Osmotically Swollen Glial Cells." Wright State University / OhioLINK, 2008. http://rave.ohiolink.edu/etdc/view?acc_num=wright1208492663.

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20

Ng, Wai Yee. "Ginsenosides on the growth and proliferation of glial tumor cells." HKBU Institutional Repository, 2008. http://repository.hkbu.edu.hk/etd_ra/998.

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21

Tassoni, Alessia. "Retinal glial responses to mesenchymal stem cell transplantation." Thesis, University of Cambridge, 2015. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.709042.

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22

李勝修 and Shengxiu Li. "The role of glial cells in the survival and axonal regeneration of retinal ganglion cells." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 1998. http://hub.hku.hk/bib/B31238932.

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23

Li, Shengxiu. "The role of glial cells in the survival and axonal regeneration of retinal ganglion cells /." Hong Kong : University of Hong Kong, 1998. http://sunzi.lib.hku.hk/hkuto/record.jsp?B20897650.

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24

Gale, Zoe. "Glial cell line-derived neurotrophic factor effects on dental pulp cells and osteoblast-like cells." Thesis, University of Birmingham, 2012. http://etheses.bham.ac.uk//id/eprint/3268/.

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Glial cell line-derived neurotrophic factor (GDNF) is a growth factor promoting survival, proliferation and differentiation of neural crest cells. Neural crest cells play an important role within mesenchymal tissues during dental pulp and calvarial bone development. GDNF also has a role within non-neuronal tissues and is expressed during dental development. GDNF null mutations prevent the formation of the mineralised hard tissues of the tooth. The hypothesis for this study was that GDNF affects mesenchymal dental pulp cells (DPC), promoting the regenerative responses of mineralised tissues. Th

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25

Donohue, Carolyn Elizabeth. "EXPRESSION OF Npcl IN GLIAL CELLS CORRECTS STERILITY IN Npcl-/- MICE." Thesis, The University of Arizona, 2009. http://hdl.handle.net/10150/192331.

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26

Teare, Katrina Anne. "Designing a delivery system for glial cells for spinal cord repair." Thesis, University of Nottingham, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.428927.

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27

Mouzannar, Raymond. "Higher order chromatin degradation induced by hydrogen peroxide in glial cells." Morgantown, W. Va. : [West Virginia University Libraries], 2001. https://etd.wvu.edu/etd/controller.jsp?moduleName=documentdata&jsp%5FetdId=2098.

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Thesis (Ph. D.)--West Virginia University, 2001.<br>Title from document title page. Document formatted into pages; contains viii, 84 p. : ill. Includes abstract. Includes bibliographical references (p. 58-84).

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28

De, Pascalis Chiara. "Role of intermediate filaments in collective cell migration of glial cells." Thesis, Paris 6, 2017. http://www.theses.fr/2017PA066026.

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Pendant la morphogenèse, la réparation des tissus et le cancer, les cellules peuvent migrer en manière mésenchymateuse et collective. Le cytosquelette est essentiel pour la migration, mais alors que l'actine et les microtubules ont été largement étudiés, le rôle des filaments intermédiaires (FIs) est encore largement inconnu. La déplétion des FI diminue souvant la vitesse de migration et les FI sont fréquemment surexprimé dans les tumeurs invasives. Pour ces propriétés, nous supposons que les FIs peuvent jouer un rôle clé dans la mécanique cellulaire pendant la migration.Pour étudier le rôle d

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29

Coulibaly, Aminata P. "Changes in Sympathetic Preganglionic Neurons and Associated Glial Cells following Injury." Miami University / OhioLINK, 2010. http://rave.ohiolink.edu/etdc/view?acc_num=miami1281032308.

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30

Eduafo, Augusta K. "Mechanisms of Hyperglycemia-Induced ROS Production in Osmotically Swollen Glial Cells." Wright State University / OhioLINK, 2015. http://rave.ohiolink.edu/etdc/view?acc_num=wright1433185840.

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31

Lawton, Michelle. "The effect of heavy metals on differentiated neuronal and glial cells." Thesis, Nottingham Trent University, 2007. http://irep.ntu.ac.uk/id/eprint/219/.

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Heavy metal poisoning poses a serious health risk among populations worldwide. The symptoms presented by exposure are varied and depend upon the species of the metal, the age of the individual and the exposure dose. All heavy metals have debilitating effects on the CNS. Children are especially sensitive to the neurological effects due to the intense growth and activity of a developing nervous system and inadequately developed defences. The aims of this study were to determine the effects of sub-lethal concentrations of numerous heavy metals on neuronal and glial cell differentiation. Using est

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32

Franceschini, Isabelle A. "Cellular and molecular studies on olfactory bulb ensheathing cells." Thesis, University of Glasgow, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.301803.

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33

Downing, Trevor. "THE RELATIONSHIP BETWEEN LACTIC ACID, REACTIVE OXYGEN SPECIES AND THE HYPOXIA-INDUCED ACIDIFICATION SEEN IN CHEMOSENSITIVE NEURONS OF THE NUCLEUS TRACTUS SOLITARIUS (NTS)." Wright State University / OhioLINK, 2006. http://rave.ohiolink.edu/etdc/view?acc_num=wright1158455199.

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34

Jacques, Cécile Giangrande Angela. "Étude du rôle et du mécanisme d'action des facteurs de transcription Glial cell deficient/Glial cells missing au cours du développement." Strasbourg : Université de Strasbourg, 2009. http://eprints-scd-ulp.u-strasbg.fr:8080/1139/01/JACQUES_Cecile_2007.pdf.

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35

Jacques, Cécile. "Etude du rôle et du mécanisme d'action des facteurs de transcription glial cell deficient/glial cells missing au cours du développement." Université Louis Pasteur (Strasbourg) (1971-2008), 2007. https://publication-theses.unistra.fr/public/theses_doctorat/2007/JACQUES_Cecile_2007.pdf.

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Les facteurs de transcription Gcm et Gcm2 sont connus pour leur rôle de déterminants gliaux et plasmatocytaires chez l’embryon de drosophile. Lors de ma thèse, j’ai mis en évidence que les gènes gcm-gcm2 sont requis pour la différenciation terminale d’une sous-population de cellules tendon. Par la suite, nous avons montré que l’orthologue c-GCM1 chez le poulet est requis lors de l’embryogenèse pour la différenciation des précurseurs neuraux de la moelle épinière en neurones. De façon surprenante, nous avons également mis en évidence que les gènes de type gcm sont exprimés et requis dans des li

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36

楊鐸輝 and Tok-fai Vincent Yeung. "Aspects of the biological interactions between natriuretic peptides and cultured glial cells." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 1997. http://hub.hku.hk/bib/B31981665.

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37

Davis, Hedvika. "Glial differentiation of human umbilical stem cells in 2D and 3D environments." Doctoral diss., University of Central Florida, 2011. http://digital.library.ucf.edu/cdm/ref/collection/ETD/id/4931.

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During differentiation stem cells are exposed to a range of microenvironmental chemical and physical cues. In this study, human multipotent progenitor cells (hMLPCs) were differentiated from umbilical cord into oligodendrocytes and astrocytes. Chemical cues were represented by a novel defined differentiation medium containing the neurotransmitter norepinephrine (NE). In traditional 2 dimensional (2D) conditions, the hMLPCs differentiated into oligodendrocyte precursors, but did not progress further. However, in a constructed 3 dimensional (3D) environment, the hMLPCs differentiated into commit

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38

Yeung, Tok-fai Vincent. "Aspects of the biological interactions between natriuretic peptides and cultured glial cells." Hong Kong : University of Hong Kong, 1997. http://sunzi.lib.hku.hk/hkuto/record.jsp?B18650302.

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39

Coronel, Marco V. "Effects of Brain Injury on Primary Cilia of Glial Cells and Pericytes." Thesis, University of North Texas, 2016. https://digital.library.unt.edu/ark:/67531/metadc955100/.

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Glial cells maintain homeostasis that is essential to neuronal function. Injury to the nervous system leads to the activation and proliferation of glial cells and pericytes, which helps to wall off the damaged region and restore homeostatic conditions. Sonic hedgehog is a mitogen which is implicated in injury-induced proliferation of glial cells and pericytes. The mitogenic effects of sonic hedgehog require primary cilia, but the few reports on glial or pericyte primary cilia do not agree about their abundance and did not address effects of injury on these cilia. Primary cilia are microtubule-

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40

Beligala, Dilshan Harshajith. "Stem-like cells and glial progenitors in the adult mouse suprachiasmatic nucleus." Bowling Green State University / OhioLINK, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=bgsu1566319291491512.

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41

Siqueiros, Márquez Lourdes Montserrat. "Regulation of dystrophin Dp71 during Müller glial cells edema in mouse retina." Thesis, Paris 6, 2017. http://www.theses.fr/2017PA066361/document.

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La rupture de la barrière hémato-rétinienne interne (iBRB) se produit dans de nombreux troubles de la rétine et peut provoquer un œdème rétinien souvent responsable de la perte de vision. Le but de cette étude était de caractériser l'impact d'une rupture de l’iBRB sur les changements homéostatiques rétiniens de la dystrophine Dp71, AQP4 et Kir4.1 provoqués par les altérations les cellules gliales de Müller CGM. L'effet protecteur de la Dex a été étudié dans ce modèle. Par ailleurs, les explants rétiniens ont été utilisé pour étudier la formation et la résolution de l'œdème de CGM sans l'influe

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42

Kanumilli, Srinivasan. "An investigation of glial metabotropic glutamate receptors and their signalling mechanisms." Thesis, University of Bristol, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.364911.

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43

Siefert, Matthew Emerson. "GLIAL CELL REMODELING DURING TERMINAL NERVE TRUNK FORMATION IN DROSOPHILA MELANOGASTER." Miami University / OhioLINK, 2013. http://rave.ohiolink.edu/etdc/view?acc_num=miami1386158957.

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44

Couturier, Aude. "Effect of high lipid exposure on retinal glial cell activation." Thesis, Sorbonne université, 2018. http://www.theses.fr/2018SORUS501.

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La rétinopathie diabétique (RD) reste la première cause de cécité dans la population active dans les pays industrialisés et les traitements actuels ne sont pas totalement satisfaisants. De nombreuses études ont démontré l’implication précoce de l’activation des cellules gliales de Müller (CGMs) dans la survenue de la RD, même avant l’apparition des lésions vasculaires. Par ailleurs, le glucose ne serait pas le seul facteur impliqué dans ces modifications vasculaires et inflammatoires, et des études récentes ont montré le rôle de la dyslipidémie et des acides gras dans la RD. L’objectif de ce t

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45

Siu, Vincent. "MGMT promoter methylation and expression in glial tumours and peripheral blood mononuclear cells." Thesis, McGill University, 2010. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=86563.

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O6-Methylguanine DNA methyltransferase (MGMT) is an inducible DNA repair protein that acts to repair damage by DNA alkylating agents currently used in chemotherapy, such as temozolomide. MGMT removes the alkyl group placed at the O6-position of guanine by these alkylating agents, decreasing their efficacy. It has been shown that epigenetic methylation of the O6-MGMT DNA promoter region in tumour tissue from glioblastoma multiforme (GBM) is associated with improved survival from patients treated with temozolomide and concomitant radiotherapy. We wanted to assess the levels of MGMT promoter meth

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46

di, Domenico Angelique. "Investigating Glial Contributions During Parkinson’s Disease Pathogenesis Using Patient-Specific iPSC-Derived Cells." Doctoral thesis, Universitat de Barcelona, 2017. http://hdl.handle.net/10803/462955.

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La malaltia de Parkinson (PD) s'associa amb la degeneració de les neurones dopaminèrgiques del mesencèfal ventral (vmDA) i l'acumulació d'inclusions citoplasmàtiques, els cossos de Lewy, compostos principalment per la α sinucleina agregada en les neurones vmDA supervivents. Aquest procés, juntament amb els mecanismes patogènics autònoms cel·lulars subjacents, s'ha modelat fins ara amb èxit utilitzant tecnologia de cèl·lules mare pluripotents induïdes de cada pacient (iPSC). En el nostre laboratori, vam generar astròcits de línies d'iPSC derivades de pacients amb PD familiar amb la mutació G20

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47

Janßen, Stefanie [Verfasser]. "Studies on the role of glial cells in inflammation and regeneration / Stefanie Janßen." Hannover : Bibliothek der Tierärztlichen Hochschule Hannover, 2014. http://d-nb.info/1054312990/34.

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48

Sahni, V. "The transplantation and differentiation of glial-biased stem-like cells from peripheral nerves." Thesis, University College London (University of London), 2009. http://discovery.ucl.ac.uk/17969/.

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The generation of Schwann cells is preceded by the generation of the Schwann cell precursor (SCP), a cell type that differs in a number of ways from migrating crest cells and Schwann cells. SCPs can be considered as glial-biased stem-like cells and I report that they have favourable properties as myelin repair cells. In particular, they are able to migrate through normal central nervous system tissue to reach demyelinated lesions, unlike Schwann cells, while at the lesion site they differentiate to generate peripheral type myelin. Although this finding was promising, in order for SCPs to be su

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49

Vrotsos, Emmanuel. "MCP-1 and APP Involvement of Glial Differentiation and Migration of Neuroprogenitor Cells." Doctoral diss., University of Central Florida, 2009. http://digital.library.ucf.edu/cdm/ref/collection/ETD/id/3421.

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Neuroprogenitor cells are an important resource because of their potential to replace damaged cells in the brain caused by trauma and disease. It is of great importance to better understand which factors influence the differentiation and migration of these cells. Previously it has been reported that neuroprogenitor cells undergoing apoptotic stress have increased levels of Amyloid precursor protein (APP) and increased APP expression results in glial differentiation. APP activity was also shown to be required for staurosporine induced glial differentiation of neuroprogenitor cells. Monocyte che

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50

Vrotsos, Emmanuel George. "MCP-1 and APP involvement in glial differentiation and migration of neuroprogenitor cells." Orlando, Fla. : University of Central Florida, 2009. http://purl.fcla.edu/fcla/etd/CFE0002517.

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