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Journal articles on the topic 'Nutrigenomic'

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1

Akintunde, Adeyinka, Imam Mustofa, Lois Ndubuisi-Ogbonna, et al. "<b>Nutrigenomics: A tool to unlock genetic potential of Nigerian indigenous goat breeds</b>." Open Veterinary Journal 15, no. 6 (2025): 2298. https://doi.org/10.5455/ovj.2025.v15.i6.4.

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Nigerian indigenous goats represent a valuable genetic resource for meat and milk production. However, their productivity often falls below their genetic potential due to suboptimal nutrition. Nutrigenomics offers a revolutionary approach to bridge this gap by exploring the interaction between nutrients and goat genes. It explores how nutrigenomic tools can be used to identify gene variants associated with feed efficiency, meat quality, and milk production. There are various technologies designed to ensure genetic potentials are realized. Nutrigenomics is aimed at exploiting the non-coding sec
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Maranhão, Priscila, Gustavo Bacelar-Silva, Duarte Ferreira, Conceição Calhau, Pedro Vieira-Marques, and Ricardo Cruz-Correia. "Nutrigenomic Information in the openEHR Data Set." Applied Clinical Informatics 09, no. 01 (2018): 221–31. http://dx.doi.org/10.1055/s-0038-1635115.

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Background The traditional concept of personalized nutrition is based on adapting diets according to individual needs and preferences. Discussions about personalized nutrition have been on since the Human Genome Project, which has sequenced the human genome. Thenceforth, topics such as nutrigenomics have been assessed to help in better understanding the genetic variation influence on the dietary response and association between nutrients and gene expression. Hence, some challenges impaired the understanding about the nowadays important clinical data and about clinical data assumed to be import
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Miroshina, Tatiana, and Irina Reznichenko. "Nutrigenomics and Nutrigenetics Importance in the Food Science." Food Industry 8, no. 2 (2023): 105–15. http://dx.doi.org/10.29141/2500-1922-2023-8-2-11.

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Nutrigenomics is a relatively new discipline, but it has huge potential for the prevention and treatment of certain types of diseases. The presented review enables scientists and medical professionals to get useful information about the nutrigenomics role in the prevention of diseases related to nutrition and lifestyle. The study aims at analyzing, systematizing and generalizing scientific data on the nutrigenetics and nutrigenomics role in the food systems technology development. The manuscript describes the search results for scientific articles and regulatory documents in the electronic dat
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Ανεστίδου (Anastasia Ioanna Anestidou), Αναστασία Ιωάννα, Τατιανή Σπυροπούλου (Tatiani Spyropoulou), Μαρία Κουρκουτίδου (Maria Kourkoutidou) та ін. "Η Διατροφογονιδιωματική και οι εμπορικά διαθέσιμες εφαρμογές της υπό το πρίσμα της Βιοηθικής". Bioethica 3, № 1 (2017): 15. http://dx.doi.org/10.12681/bioeth.19863.

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Nutrigenomics, an emerging genomics field, aims to explore the interactions between nutrition and genes. Notably, nutrigenomics information and applications seem to be directly accessible to the public, partly due to advertising and direct-to-consumer online sales of nutrigenomics-related products and services. Nowadays, consumers have direct access to their genetic information. Access, however, does not guarantee interpretation and utility.This article, discusses the ethical and regulatory aspects of direct-to-consumer genetic services, focusing on nutrigenomic tests and the means they are pr
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ADEMILUYI, DARE DAMILOLA. "Knowledge and Perception of Undergraduate Students towards Nutrigenomics for Personalized Nutrition in Federal University of Agriculture, Abeokuta, Ogun State." International Journal of Innovative Science and Research Technology 7, no. 5 (2022): 545–98. https://doi.org/10.5281/zenodo.6612656.

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Nutrigenomics is a scientific study of the molecular interaction between genes and nutrients. Personalized Nutrition is the practice of adapting the diet to meet specific nutritional needs or prevent chronic disease in individuals or genetic subgroups based on the results of genetic testing. Few studies have examined how college students perceive the possibility of targeted recommendations based on their genetic make-up. Multiple companies are now offering personalized dietary advice based on the results of genetic testing. College students, who are educated and more familiar with new technolo
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Nowacka-Woszuk, Joanna. "Nutrigenomics in livestock—recent advances." Journal of Applied Genetics 61, no. 1 (2019): 93–103. http://dx.doi.org/10.1007/s13353-019-00522-x.

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Abstract The study of the effects of nutrients on genome functioning, in terms of gene transcription, protein levels, and epigenetic mechanisms, is referred to as nutrigenomics. Nutrigenomic studies in farm animals, as distinct from rodents, are limited by the high cost of keeping livestock, their long generational distance, and ethical aspects. Yet farm animals, and particularly pigs, can serve as valuable animal models for human gastrological diseases, since they possess similar size, physiology, and nutritional habits and can develop similar pathological states. In livestock, the effects of
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Putra, Agus Indra Yudhistira Diva, Nyoman Budhi Wirananda Setiawan, Made Indira Dianti Sanjiwani, Ida Ayu Ika Wahyuniari, and Agung Wiwiek Indrayani. "Nutrigenomic and Biomolecular Aspect of Moringa oleifera Leaf Powder as Supplementation for Stunting Children." Journal of Tropical Biodiversity and Biotechnology 6, no. 1 (2021): 60113. http://dx.doi.org/10.22146/jtbb.60113.

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Stunting is a global health problem. Based on WHO data, there are 161 million children who experience stunting. Breastmilk supplementation in the form of Moringa oleifera leaves powder is known to be beneficial in suppressing the stunting incidence. Moringa oleifera leaves powder contains protein, micronutrients, and minerals such as calcium, iron, sodium, vitamins C and E, beta carotene, and antioxidants (flavonoid acids, phenolic acids, glucosinolates, isothiocyanates, and saponins). The use of Moringa oleifera leaves powder in stunting cases has been carried out, but further studies in the
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8

Constantin, Nathalie, and Walter Wahli. "Nutrigenomic foods." Nutrafoods 12, no. 1 (2013): 3–12. http://dx.doi.org/10.1007/s13749-013-0014-x.

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Anna Milella, Rosa, Marica Gasparro, Maria Angela Giannandrea, Maria Notarnicola, Valeria Tutino, and Donato Antonacci. "Nutrigenomics to reveal the effects of grape consumption in healthy subjects." BIO Web of Conferences 68 (2023): 04012. http://dx.doi.org/10.1051/bioconf/20236804012.

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The Mediterranean diet places fruit and vegetables as the basis of daily nutrition. Table grape is a typical fruit of the Mediterranean tradition and is consumed worldwide. The CREA Research Centre for Viticulture and Enology has conducted nutrigenomics studies in recent years to investigate the effects of table grapes on human health. This note summarises two trials in which healthy subjects ate the black seedless grape Autumn Royal for three consecutive weeks. For our first nutrigenomic study, we used the microarray technique to analyze thousands of genes' expressions simultaneously. The res
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Riu, Deviana Soraya, Isharyah Sunarno, and Efendi Lukas. "MCM6 rs4988235 Allele G, AGT rs699 Allele C, ACE rs4343 Allele A, FADS1 rs174547 Allele C, DCHR7 rs12785878 Allele G, and GC rs7041 Allele T: Candidate Genes for Preeclampsia Prevention." Indonesian Biomedical Journal 17, no. 2 (2025): 162–71. https://doi.org/10.18585/inabj.v17i2.3422.

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BACKGROUND: Preeclampsia is the primary cause of maternal and neonatal morbidity and mortality; however, currently there is no definitive method exists to prevent preeclampsia. Recent findings indicate a possible genetic influence on preeclampsia. Therefore, this study was conducted to assess nutrigenomic patterns in preeclampsia as a potential mechanism for identifying appropriate preventive strategies through a nutrigenomic approach.METHODS: This descriptive study focused on 15 primiparous pregnant women diagnosed with preeclampsia. The nutrigenomic test was performed using DNA microarray me
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Mortensen, Alicja, Ilona K. Sorensen, Colin Wilde, et al. "Biological models for phytochemical research: from cell to human organism." British Journal of Nutrition 99, E-S1 (2008): ES118—ES126. http://dx.doi.org/10.1017/s0007114508965806.

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Nutrigenomics represents a shift of nutrition research from epidemiology and physiology to molecular biology and genetics. Nutrigenomics seeks to understand nutrition influences on homeostasis, the mechanism of genetic predispositions for diseases, to identify the genes influencing risk of diet related diseases. This review presents some in vitro models applicable in nutrigenomic studies, and discuses the use of animal models, their advantages and limitations and relevance for human situation. In vitro and in vivo models are suitable for performance of DNA microarrays, proteomic and transcript
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Meiliana, Anna, and Andi Wijaya. "Nutrigenetics, Nutrigenomics and Precision Nutrition." Indonesian Biomedical Journal 12, no. 3 (2020): 189–200. http://dx.doi.org/10.18585/inabj.v12i3.1158.

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BACKGROUND: Since our conception to death, we were permanently exposed to nutrition. Indeed, food intake is the key of the environmental factor that modulates our gene. Nutrigenomics focus on how common dietary chemicals altering an individual’s genetic makeup including genome, proteome, and metabolome. While nutrigenetics refer to how the genetic variation gives different responses to nutrients.CONTENT: Nutrigenomics applied the high-throughput genomic-related tools to find out the influence of nutrients on the genes’ expression. While nutrigenetics (nutritional genetics) focus on the heterog
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Fauzi, Nurulwahidah, Robiatul Adawiyah Mohd @ Amat, and Norzulaili Mohd Ghazali. "Integrating Nutrigenomics and Traditional Wisdom: A Study of Dietary Ethics in Islamic Hadith and Kitab Al-Rahmah Fi Al-Tibb Wa Al-Hikmah." Ulum Islamiyyah 36, no. 03 (2024): 79–97. https://doi.org/10.33102/uij.vol36no03.619.

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This paper explores the integration of nutrigenomics with traditional wisdom, specifically focusing on dietary ethics found in Islamic Hadith and Malay medicine manuscripts. By merging contemporary scientific approaches with indigenous practices, the study aims to provide a holistic understanding of how these combined methodologies can enhance health and wellness. The research delves into various herbs and plants, examining their medicinal properties and the traditional methods of their use as documented in historical texts. The goal is to identify potential synergies between modern nutrigenom
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Batheja, Sapna, Emma M. Schopp, Samantha Pappas, Siri Ravuri, and Susan Persky. "Characterizing Precision Nutrition Discourse on Twitter: Quantitative Content Analysis." Journal of Medical Internet Research 25 (October 12, 2023): e43701. http://dx.doi.org/10.2196/43701.

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Background It is possible that tailoring dietary approaches to an individual’s genomic profile could provide optimal dietary inputs for biological functioning and support adherence to dietary management protocols. The science required for such nutrigenetic and nutrigenomic profiling is not yet considered ready for broad application by the scientific and medical communities; however, many personalized nutrition products are available in the marketplace, creating the potential for hype and misleading information on social media. Twitter provides a unique big data source that provides real-time i
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Dhanapal, Anto Cordelia T. A., Ramatu Wuni, Eduard F. Ventura, et al. "Implementation of Nutrigenetics and Nutrigenomics Research and Training Activities for Developing Precision Nutrition Strategies in Malaysia." Nutrients 14, no. 23 (2022): 5108. http://dx.doi.org/10.3390/nu14235108.

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Nutritional epidemiological studies show a triple burden of malnutrition with disparate prevalence across the coexisting ethnicities in Malaysia. To tackle malnutrition and related conditions in Malaysia, research in the new and evolving field of nutrigenetics and nutrigenomics is essential. As part of the Gene-Nutrient Interactions (GeNuIne) Collaboration, the Nutrigenetics and Nutrigenomics Research and Training Unit (N2RTU) aims to solve the malnutrition paradox. This review discusses and presents a conceptual framework that shows the pathway to implementing and strengthening precision nutr
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Marotta, Francesco, Gulcin Sagdicoglu Celep, Anna Cabeca, and Ascanio Polimeni. "Novel concepts on functional foods and nutrigenomics in healthy aging and chronic diseases: a review of fermented papaya preparation research progress." Functional Foods in Health and Disease 2, no. 5 (2012): 120. http://dx.doi.org/10.31989/ffhd.v2i5.94.

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Functional foods are an emerging research field corresponding with genomical, epidemiological and clinical studies integrated with the food industry in accordance with the consumer demands. Consequently, the features of the functional foods are being discussed by various researchers and related institutions, and a common view has been pointed out about the availability and the nature of the components of functional foods. Recently, the outcomes of functional foods are being assessed by the help of all the available scientific tools. Genomic medicine is one of the most promising areas of resear
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Caradonna, Fabio, Ornella Consiglio, Claudio Luparello, and Carla Gentile. "Science and Healthy Meals in the World: Nutritional Epigenomics and Nutrigenetics of the Mediterranean Diet." Nutrients 12, no. 6 (2020): 1748. http://dx.doi.org/10.3390/nu12061748.

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The Mediterranean Diet (MD), UNESCO Intangible Cultural Heritage of Humanity, has become a scientific topic of high interest due to its health benefits. The aim of this review is to pick up selected studies that report nutrigenomic or nutrigenetic data and recapitulate some of the biochemical/genomic/genetic aspects involved in the positive health effects of the MD. These include (i) the antioxidative potential of its constituents with protective effects against several diseases; (ii) the epigenetic and epigenomic effects exerted by food components, such as Indacaxanthin, Sulforaphane, and 3-H
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Ray, Subhasree. "Personalized Modification of Breast Milk to Help Enhancing Nutrition Profile of Neonates: A short Communication." Current Research in Nutrition and Food Science Journal 2, no. 1 (2014): 47–50. http://dx.doi.org/10.12944/crnfsj.2.1.07.

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Personalized Nutrition means in practice, adapting food to individual needs, depending on the host’s genome, this calls for an emerging field of nutrigenomic approach in order to build the tools for individualized diet, health maintenance and disease prevention. Based on this principle, breast milk is now being analyzed, modified and administered in smaller infants to provide them personalized diet, ensuring the premature infants are receiving correct amounts of nutrients they need to thrive. In the past, all milk was fortified to the same and it was ‘one-size-fits-all’. Now, nutrigenomics is
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Janssens, A. Cecile JW, Eline M. Bunnik, Wylie Burke, and Maartje HN Schermer. "Uninformed consent in nutrigenomic research." European Journal of Human Genetics 25, no. 7 (2017): 789–90. http://dx.doi.org/10.1038/ejhg.2017.63.

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Tucker, Katherine L., Caren E. Smith, Chao-Qiang Lai, and Jose M. Ordovas. "Quantifying Diet for Nutrigenomic Studies." Annual Review of Nutrition 33, no. 1 (2013): 349–71. http://dx.doi.org/10.1146/annurev-nutr-072610-145203.

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Takahashi, Yoko. "Nutrigenomic analysis of food functionality." Journal of Lipid Nutrition 21, no. 1 (2012): 51–57. http://dx.doi.org/10.4010/jln.21.51.

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Kaput, Jim. "Nutrient selection through nutrigenomic approaches." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 292, no. 1 (2007): R204—R206. http://dx.doi.org/10.1152/ajpregu.00658.2006.

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Elliott, R. M., and I. T. Johnson. "Nutrigenomic approaches for obesity research." Obesity Reviews 8, s1 (2007): 77–81. http://dx.doi.org/10.1111/j.1467-789x.2007.00323.x.

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Duchnik, Ewa, Joanna Kruk, Aleksandra Tuchowska, and Mariola Marchlewicz. "The Impact of Diet and Physical Activity on Psoriasis: A Narrative Review of the Current Evidence." Nutrients 15, no. 4 (2023): 840. http://dx.doi.org/10.3390/nu15040840.

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Psoriasis is an inflammatory disease with strong genetic links and numerous features of autoimmunity that are also influenced by environment and lifestyle, including nutritional factors and physical activity (PA), with regards to the condition of patients. Recent reports in the field of nutrigenomics indicate a significant impact of nutrients in modulating microRNAs. However, few studies have evaluated the effect of nutritional systems and PA on treating psoriasis. This narrative review updates information regarding the current dietary recommendations for individuals with psoriasis and discuss
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Ruskovska, Tatjana, Marika Massaro, Maria Annunziata Carluccio, et al. "Systematic bioinformatic analysis of nutrigenomic data of flavanols in cell models of cardiometabolic disease." Food & Function 11, no. 6 (2020): 5040–64. http://dx.doi.org/10.1039/d0fo00701c.

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Utkina, Aleksandra, and Vasiliy Karagodin. "Opportunities of Digital Technologies as a Tool for Improving and Personalizing Specialized Nutrition." SHS Web of Conferences 93 (2021): 04013. http://dx.doi.org/10.1051/shsconf/20219304013.

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The possibilities of nutrigenomics as an approach to determining the effectiveness of specialized food products have been studied. For this purpose, the influence of consumption of whey protein concentrate FitPROTEIN and the carrier of branched-chain amino acids SPORTAMIN®BCAA 6000 on the expression of the target gene FTO was determined. Despite a certain similarity in the composition of these products, their effect on the average level of FTO gene expression is significantly different. The results obtained are discussed from the standpoint of identification of the target gene, detection of ge
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Riccardi, Bruno, Sergio Resta, and Roberto Fabbroni. "From Nutrigenomics to Microbiomics: New Interpretations." Journal of Biotechnology & Bioinformatics Research 3, no. 1 (2021): 1–8. http://dx.doi.org/10.47363/jbbr/2021(3)128.

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In this work we analyze the current interpretations based on the studies of Nutrigenomic and Microbiomics, according to which, at the base of many pathological and dysmetabolic manifestations, there would be or variations of single nucleotide polymorphisms (Snps), in the Nutrigenomic vision, or changes of the normal gut microbiota, in the Microbiomic conception. In particular, we analyze critically, the singular pathogenic coincidence, which for the same pathologies calls into question or Snps mutations or the presence of specific modifications of the Microbiota. Other possible causes of obser
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Kaput, Jim, Jose M. Ordovas, Lynnette Ferguson, et al. "The case for strategic international alliances to harness nutritional genomics for public and personal health." British Journal of Nutrition 94, no. 5 (2005): 623–32. http://dx.doi.org/10.1079/bjn20051585.

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Nutrigenomics is the study of how constituents of the diet interact with genes, and their products, to alter phenotype and, conversely, how genes and their products metabolise these constituents into nutrients, antinutrients, and bioactive compounds. Results from molecular and genetic epidemiological studies indicate that dietary unbalance can alter gene–nutrient interactions in ways that increase the risk of developing chronic disease. The interplay of human genetic variation and environmental factors will make identifying causative genes and nutrients a formidable, but not intractable, chall
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Penders, Bart, Rein Vos, and Klasien Horstman. "Side effects of problem-solving strategies in large-scale nutrition science: towards a diversification of health." British Journal of Nutrition 102, no. 10 (2009): 1400–1403. http://dx.doi.org/10.1017/s0007114509990651.

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Solving complex problems in large-scale research programmes requires cooperation and division of labour. Simultaneously, large-scale problem solving also gives rise to unintended side effects. Based upon 5 years of researching two large-scale nutrigenomic research programmes, we argue that problems are fragmented in order to be solved. These sub-problems are given priority for practical reasons and in the process of solving them, various changes are introduced in each sub-problem. Combined with additional diversity as a result of interdisciplinarity, this makes reassembling the original and ov
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Franzago, Marica, Daniele Santurbano, Ester Vitacolonna, and Liborio Stuppia. "Genes and Diet in the Prevention of Chronic Diseases in Future Generations." International Journal of Molecular Sciences 21, no. 7 (2020): 2633. http://dx.doi.org/10.3390/ijms21072633.

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Nutrition is a modifiable key factor that is able to interact with both the genome and epigenome to influence human health and fertility. In particular, specific genetic variants can influence the response to dietary components and nutrient requirements, and conversely, the diet itself is able to modulate gene expression. In this context and the era of precision medicine, nutrigenetic and nutrigenomic studies offer significant opportunities to improve the prevention of metabolic disturbances, such as Type 2 diabetes, gestational diabetes, hypertension, and cardiovascular diseases, even with tr
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Houghton, Christine A., Robert G. Fassett, and Jeff S. Coombes. "Sulforaphane and Other Nutrigenomic Nrf2 Activators: Can the Clinician’s Expectation Be Matched by the Reality?" Oxidative Medicine and Cellular Longevity 2016 (2016): 1–17. http://dx.doi.org/10.1155/2016/7857186.

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The recognition that food-derived nonnutrient molecules can modulate gene expression to influence intracellular molecular mechanisms has seen the emergence of the fields of nutrigenomics and nutrigenetics. The aim of this review is to describe the properties of nutrigenomic activators of transcription factor Nrf2 (nuclear factor erythroid 2-related factor 2), comparing the potential for sulforaphane and other phytochemicals to demonstrate clinical efficacy as complementary medicines. Broccoli-derived sulforaphane emerges as a phytochemical with this capability, with oral doses capable of favou
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Takamatsu, Kiyoharu, Nobuhiko Tachibana, Ichiro Matsumoto, and Keiko Abe. "Soy protein functionality and nutrigenomic analysis." BioFactors 21, no. 1-4 (2004): 49–53. http://dx.doi.org/10.1002/biof.552210110.

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Sánchez, José Antonio Cayuela, and Abdelaziz Elamrani. "Nutrigenomics of Essential Oils and their Potential Domestic Use for Improving Health." Natural Product Communications 9, no. 11 (2014): 1934578X1400901. http://dx.doi.org/10.1177/1934578x1400901128.

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The use of essential oils as industrial food additives is notorious, like their medicinal properties. However, their use in household food spicing is for now limited. In this work, we have made a review to reveal the nutrigenomic actions exerted by their bioactive components, to promote awareness of their modulating gene expression ability and the potential that this implies. Also considered is how essential oils can be used as flavoring and seasoning after cooking and before consumption, such as diet components which can improve human health. Genetic mechanisms involved in the medicinal prope
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Konstantinidou, Valentini, and Sarela Garcia-Santamarina. "Moving forward the Effects of Gene–Diet Interactions on Human Health." Nutrients 14, no. 18 (2022): 3782. http://dx.doi.org/10.3390/nu14183782.

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Dave, Asim, Eun-Jung Park, Sumi Piya, and John M. Pezzuto. "Long-Term Dietary Consumption of Grapes Alters Phenotypic Expression in Skeletal Muscle of Aged Male and Female Mice." Foods 14, no. 4 (2025): 695. https://doi.org/10.3390/foods14040695.

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(1) Background: Nutrigenomics investigates how diet influences gene expression and how genetic variation impacts dietary responses. Grapes, rich in phytochemicals, exhibit potential disease-preventive properties through nutrigenomic mechanisms rather than direct chemical interactions. This study aimed to explore the modulation of gene expression in muscle tissue resulting from long-term grape consumption. (2) Methods: A mouse model was employed to assess gene expression in the skeletal muscles of males and females fed a grape-enriched diet versus a bland diet over 2.5 years. Heatmaps and princ
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Musa, Ibrahim Suleiman, Hafsat Ibrahim Okuba, and Bilkisu Azores Musa. "PREDICTING THE EFFECTS OF NUTRIENTS AND BIOACTIVE COMPOUNDS ON THE EXPRESSION OF LOW DENSITY LIPOPROTEIN RECEPTOR (LDLR) USING IN SILICO APPROACH." FUDMA JOURNAL OF SCIENCES 8, no. 6 (2024): 598–600. https://doi.org/10.33003/fjs-2024-0806-3192.

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The objective of the study was to evaluate the effects of some nutrients and bioactive compounds on the expression of low density lipoprotein receptor using computational method. Low density lipoprotein accounts for 70% of circulating plasma cholesterol which is regulated by low density lipoprotein receptor. The evaluation of low density lipoprotein receptor expression was done using the Nutrigenome Data Base which is composed of manually curated differentially expressed genes from treatments with nutrients and bioactive compounds obtained from nutrigenomic experiments. Significant up regulati
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Samuel O. Olorunkoya, Oluwatobi Fijabi, Oluseyi V. Alagbe, and Mowumi Olatinwo. "Harnessing the role of nutrigenomics for feed efficiency utilization in cattle: Opportunities and challenges." Engineering Science & Technology Journal 5, no. 7 (2024): 2139–56. http://dx.doi.org/10.51594/estj.v5i7.1308.

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Nutrigenomics, the study of the interaction between nutrition and genes, presents a transformative approach to enhancing feed efficiency in cattle. This field leverages genetic insights to optimize dietary formulations, aiming to improve nutrient utilization and overall productivity. With the global demand for meat and dairy products rising, increasing feed efficiency is critical for economic viability and environmental sustainability in the livestock industry. The role of nutrigenomics in cattle feed efficiency encompasses several key areas. Precision nutrition is one of the foremost opportun
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Bhattacharya, Tanima, Soumam Dutta, Rokeya Akter, et al. "Role of Phytonutrients in Nutrigenetics and Nutrigenomics Perspective in Curing Breast Cancer." Biomolecules 11, no. 8 (2021): 1176. http://dx.doi.org/10.3390/biom11081176.

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Breast cancer (BC) is one of the most common type of cancer and an important contributor to female mortality. Several genes and epigenetic modifications are involved in the development and progression of BC. Research in phytochemistry, nutrigenomics, and nutrigenetics has provided strong evidence that certain phytonutrients are able to modulate gene expression at transcriptional and post-transcriptional levels. Such phytonutrients may also be beneficial to prevent and treat BC. In this review, we will focus on the nutrigenomic effects of various phytochemicals including polyphenols, phytostero
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Hassan, Faiz-ul, Asif Nadeem, Zhipeng Li, et al. "Role of Peroxisome Proliferator-Activated Receptors (PPARs) in Energy Homeostasis of Dairy Animals: Exploiting Their Modulation through Nutrigenomic Interventions." International Journal of Molecular Sciences 22, no. 22 (2021): 12463. http://dx.doi.org/10.3390/ijms222212463.

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Peroxisome proliferator-activated receptors (PPARs) are the nuclear receptors that could mediate the nutrient-dependent transcriptional activation and regulate metabolic networks through energy homeostasis. However, these receptors cannot work properly under metabolic stress. PPARs and their subtypes can be modulated by nutrigenomic interventions, particularly under stress conditions to restore cellular homeostasis. Many nutrients such as polyunsaturated fatty acids, vitamins, dietary amino acids and phytochemicals have shown their ability for potential activation or inhibition of PPARs. Thus,
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Hervina, Hervina, I. Dewa Made Sukrama, and I. Made Jawi. "IMPLEMENTATION NUTRIGENOMIC OF VITAMIN D IN PERIODONTITIS." Journal of Vocational Health Studies 6, no. 1 (2022): 73–77. http://dx.doi.org/10.20473/jvhs.v6.i1.2022.73-77.

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Background: Nutrition is a significant risk factor for the incidence of periodontal disease. Nutrients acting on the human genome, either directly or indirectly, can change the expression and structure of genes. One of the micronutrients associated with periodontitis is vitamin D. Vitamin D has an important role in bone and calcium metabolism and regulates serum calcium and phosphate concentrations at normal limits. Purpose: To discuss the nutritional vitamin D as an essential micronutrient in preventing and accelerating healing in periodontitis. Review: Searched two databases from article pub
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Mlodzik-Czyzewska, Monika A., and Agata Chmurzynska. "The State of Nutrigenomic Education in Poland." Lifestyle Genomics 11, no. 2 (2018): 90–98. http://dx.doi.org/10.1159/000494332.

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Chung, Soonkyu, Young Jun Kim, Soo Jin Yang, Yunkyoung Lee, and Myoungsook Lee. "Nutrigenomic Functions of PPARs in Obesogenic Environments." PPAR Research 2016 (2016): 1–17. http://dx.doi.org/10.1155/2016/4794576.

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Peroxisome proliferator-activated receptors (PPARs) are ligand-activated transcription factors that mediate the effects of several nutrients or drugs through transcriptional regulation of their target genes in obesogenic environments. This review consists of three parts. First, we summarize current knowledge regarding the role of PPARs in governing the development of white and brown/beige adipocytes from uncommitted progenitor cells. Next, we discuss the interactions of dietary bioactive molecules, such as fatty acids and phytochemicals, with PPARs for the modulation of PPAR-dependent transcri
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Gladine, Cécile, and André Mazur. "Nutrigenomic effects of omega-3 fatty acids." Lipid Technology 26, no. 10 (2014): 227–29. http://dx.doi.org/10.1002/lite.201400055.

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Ozanne, Susan. "Nutrigenomic programming of cardiovascular and metabolic diseases." Free Radical Biology and Medicine 75 (October 2014): S11. http://dx.doi.org/10.1016/j.freeradbiomed.2014.10.857.

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Varghese, Naveen Jacob, and Pinku Thekkemelathethil Thomas. "Nutrigenomic Aspects Over Dental Health: A Review." Journal of Pharmaceutical Research International 37, no. 1 (2025): 77–82. https://doi.org/10.9734/jpri/2025/v37i17649.

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People living in different cultures have different genetic compositions, which affects the uptake and breakdown of nutrients. Investigators found that certain changes have resulted in the genomes due to the nutrient demand. Dental diseases like periodontitis are caused by the disparity between the oral microorganisms and the inflammatory condition of the individual. The disease development is affected by genetic and environmental factors, which can affect the immune system, thereby altering the connective tissue and bone support. Even periodontitis is seen mostly in adults, as well as in child
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De Santis, Stefania, Marica Cariello, Elena Piccinin, Carlo Sabbà, and Antonio Moschetta. "Extra Virgin Olive Oil: Lesson from Nutrigenomics." Nutrients 11, no. 9 (2019): 2085. http://dx.doi.org/10.3390/nu11092085.

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Extra virgin olive oil (EVOO) consumption has a beneficial effect on human health, especially for prevention of cardiovascular disease and metabolic disorders. Here we underscore the peculiar importance of specific cultivars used for EVOO production since biodiversity among cultivars in terms of fatty acids and polyphenols content could differently impact on the metabolic homeostasis. In this respect, the nutrigenomic approach could be very useful to fully dissect the pathways modulated by different EVOO cultivars in terms of mRNA and microRNA transcriptome. The identification of genes and miR
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Ruskovska, Tatjana, Irena Budić-Leto, Karla Fabiola Corral-Jara, et al. "Systematic Bioinformatic Analyses of Nutrigenomic Modifications by Polyphenols Associated with Cardiometabolic Health in Humans—Evidence from Targeted Nutrigenomic Studies." Nutrients 13, no. 7 (2021): 2326. http://dx.doi.org/10.3390/nu13072326.

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Cardiometabolic disorders are among the leading causes of mortality in the human population. Dietary polyphenols exert beneficial effects on cardiometabolic health in humans. Molecular mechanisms, however, are not completely understood. Aiming to conduct in-depth integrative bioinformatic analyses to elucidate molecular mechanisms underlying the protective effects of polyphenols on cardiometabolic health, we first conducted a systematic literature search to identify human intervention studies with polyphenols that demonstrate improvement of cardiometabolic risk factors in parallel with signifi
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Veterini, Anna Surgean, Bambang Pujo Semedi, Prananda Surya Airlangga, et al. "Preliminary study: the future insight of relationship between nutrigenomic risk and sepsis." Bali Medical Journal 13, no. 1 (2024): 581–91. https://doi.org/10.15562/bmj.v13i1.4994.

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Link of Video Abstract: https://youtu.be/K5y8Rmm7JZk Introduction: In field observations, we frequently encountered cases of sepsis at a young age and rarely in older individuals. Most cases are caused by a bacterial infection, which causes pneumonia that progresses to septic shock. There are several possible causes of infection and subsequent septic shock. Among these, certain genetic code abnormalities cause disturbances in nutrient metabolism, which facilitates the emergence of infections. This study aimed to explore the nutrigenomic patterns in patients with septic shock. Methods: Nutrigen
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Kuzmar, Isaac. "Food, Genomic and Nutrigenomic: Fighting the Obesity Epidemic." International Journal of Food and Nutritional Science 2, no. 6 (2015): 1–2. http://dx.doi.org/10.15436/2377-0619.15.e005.

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Milenkovic, Dragan. "MicroRNAs as novel nutrigenomic targets for cardiovascular health." Free Radical Biology and Medicine 75 (October 2014): S11. http://dx.doi.org/10.1016/j.freeradbiomed.2014.10.856.

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