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Journal articles on the topic 'Oapi'

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1

Daniar, Rima, and Nurul Kholidah. "Effect of catalysts on the conversion of polystyrene plastic waste into fuel with the Catalytic Cracking Method." ALKIMIA : Jurnal Ilmu Kimia dan Terapan 4, no. 1 (2020): 24–29. http://dx.doi.org/10.19109/alkimia.v4i1.5469.

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Polystyrene is useful product that widely used today. But when it becomes waste, Polystyrene can cause environmental problem such as air pollution, soil contamination, as well as economical resistence due to the increase of space and disposal costs. On the other hand Polystyrene can be converted into fuel. It is expected can be a solution of the problem. The aim of this research is to convert polystyrene plastic waste into useful fuel with catalytic cracking process. Zeolit and Al2O3 was used as catalyst in this research as musch as 8 % feed. Temperature set at 250 oC. At the optimum reaction
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Liu, Daxue, Jun Wu, and Xin Xu. "Multi-agent reinforcement learning using ordinal action selection and approximate policy iteration." International Journal of Wavelets, Multiresolution and Information Processing 14, no. 06 (2016): 1650053. http://dx.doi.org/10.1142/s0219691316500533.

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Multi-agent reinforcement learning (MARL) provides a useful and flexible framework for multi-agent coordination in uncertain dynamic environments. However, the generalization ability and scalability of algorithms to large problem sizes, already problematic in single-agent RL, is an even more formidable obstacle in MARL applications. In this paper, a new MARL method based on ordinal action selection and approximate policy iteration called OAPI (Ordinal Approximate Policy Iteration), is presented to address the scalability issue of MARL algorithms in common-interest Markov Games. In OAPI, an ord
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Blakeney, Michael, and Getachew Mengistie. "Intellectual property policy formulation in Africa." Queen Mary Journal of Intellectual Property 11, no. 1 (2021): 98–113. http://dx.doi.org/10.4337/qmjip.2021.01.06.

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This article examines continental, sub-regional and national initiatives in the formulation of intellectual property policy Africa. The article is divided into seven parts. The first looks at the relationship between IP and economic development. The second part examines the role of IP regional integration and trade. The third part looks at African regional trade agreements. Next, the article surveys the activities of sub-regional IP systems in Africa: the African Regional Intellectual Property Organization (ARIPO) and the Organisation Africaine de la Propriété (OAPI). The fifth part looks at t
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4

Nwabueze, Caroline Joëlle. "Challenges of Transnational Trademark Law Practice: The Case of Nigerian Companies’ Brands in OAPI States." Revue générale de droit 45, no. 1 (2015): 321–47. http://dx.doi.org/10.7202/1032041ar.

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Nigeria industrial growth has turned the country into an indispensable economic support for its neighbours. Only for the case of Cameroon, Nigeria has been the leading supplier with respectively 22% and 17.8% of imports in 2011 and 2012 with trade amounting to 328 billion FCFA per annum. This results in part from Nigerian companies’ exportations in local markets. Nigerian trademarks related to cosmetics, furniture, electronics, and pharmaceutical goods abound in neighbouring countries. However, a strengthening of Nigerian companies in regional markets encompasses strategies to avoid infringing
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Kongolo, Tshimanga. "The New Oapi Agreement as Revised in February 1999." Journal of World Intellectual Property 3, no. 5 (2005): 717–35. http://dx.doi.org/10.1111/j.1747-1796.2000.tb00151.x.

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6

Cantika, Ria, Hefly Agustian Akbar, Arizal Aswan, et al. "Pengolahan Limbah Plastik Jenis Polypropylene (PP) dan Low Density Polyethylene (LDPE) Menjadi Bahan Bakar Cair Melalui Proses Catalytic Thermal Cracking Menggunakan Katalis FCC." Jurnal Pendidikan dan Teknologi Indonesia 2, no. 10 (2022): 437–45. http://dx.doi.org/10.52436/1.jpti.235.

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Setiap tahunnya penggunaan plastik yang semakin meningkat mengakibatkan jumlah sampah plastik yang sulit terurai semakin tinggi. Upaya mengelola sampah plastik melalui penimbunan dan pembakaran dinilai kurang tepat dan berdampak buruk bagi lingkungan. Proses Catalytic Thermal Cracking (CTC) merupakan metode yang tepat dan menguntungkan untuk mengolah limbah plastik menjadi bahan bakar cair. Pada penelitian ini, pengolahan limbah plastik jenis Polypropylene dan Low Density Polyethylene menjadi bahan bakar cair melalui Proses CatalytIc Thermal Cracking berlangsung pada temperatur CTC 200 oC, 350
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7

Ogiriki, Shadrach Olise, Jennifer Oyindamola Adepoju, Adeyinka Sikiru Yusuff, and Victor Anochie. "Physical Properties of Agbabu and Yegbata Bitumen in Nigeria." Journal of Applied Science & Process Engineering 5, no. 1 (2018): 227–41. http://dx.doi.org/10.33736/jaspe.427.2018.

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This experimental work evaluates the physical properties of Abagbu and Yegbata bitumen from Nigeria with comparison with that of Canada being the world largest producer of crude oil from bitumen. This study employed the American Society for Testing and Materials (ASTM) methods in conducting laboratory experiments in order to determine the viscosity, specific gravity, API gravity, pour point and flash point. A Gas Chromatograph (GC) was used to determine the hydrocarbon content of the bitumen samples. Test results show that the bitumen samples have specific gravity of 1.01 with a 0.9962 OAPI fo
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8

Harlivia, Rara, Tahdid Tahdid, and Sahrul Effendy A. "Pengaruh Persen Katalis Zeolit Alam Terhadap Yield Bahan Bakar Cair Proses Pirolisis dari Limbah Plastik Polypropylene." Jurnal Pendidikan dan Teknologi Indonesia 2, no. 11 (2022): 453–59. http://dx.doi.org/10.52436/1.jpti.241.

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Meningginya konsumsi energi tidak terbarukan tiap tahun terutama minyak bumi sedangkan cadangan minyak bumi di Indonesia semakin menipis dan meningkatnya penggunaan plastik yang tidak seimbang dengan pengolahan limbah merupakan masalah yang dihadapi saat ini. Salah satu upaya yang dapat menangani permasalahan tersebut adalah dengan metode pirolisis. Melalui pirolisis, plastik dapat diolah dengan aman menjadi produk cair yang bisa menjadi alternatif sumber bahan bakar. Penelitian ini bertujuan untuk mengetahui pengaruh katalis zeolit alam terhadap yield yang dihasilkan dan karakteristik dari yi
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9

Harris, Kimberly A., Zhiyuan Zhou, Michelle L. Peters, Sarah G. Wilkins, and Ronald R. Breaker. "A second RNA-binding protein is essential for ethanol tolerance provided by the bacterial OLE ribonucleoprotein complex." Proceedings of the National Academy of Sciences 115, no. 27 (2018): E6319—E6328. http://dx.doi.org/10.1073/pnas.1803191115.

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OLE (ornate, large, extremophilic) RNAs comprise a class of structured noncoding RNAs (ncRNAs) found in many extremophilic bacteria species. OLE RNAs constitute one of the longest and most widespread bacterial ncRNA classes whose major biochemical function remains unknown. In the Gram-positive alkaliphile Bacillus halodurans, OLE RNA is abundant, and localizes to the cell membrane by association with the transmembrane OLE-associated protein called OapA (formerly OAP). These characteristics, along with the well-conserved sequence and structural features of OLE RNAs, suggest that the OLE ribonuc
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10

Rajesh, Sarigama, Jiali Zhai, Calum J. Drummond, and Nhiem Tran. "Novel pH-Responsive Cubosome and Hexosome Lipid Nanocarriers of SN-38 Are Prospective for Cancer Therapy." Pharmaceutics 14, no. 10 (2022): 2175. http://dx.doi.org/10.3390/pharmaceutics14102175.

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pH-responsive nanoparticles enable the selective delivery of a chemotherapeutic agent to tumours while reducing adverse effects. Herein we synthesised four novel aminolipids and developed pH-responsive nanostructured lipid nanoparticles (LNP), which exhibited a slow-releasing hexagonal structure (H2) at physiological pH and quick release bicontinuous cubic phase (Q2) at the acidic tumour pH. The nanoparticles were used to encapsulate and control the release of the chemotherapeutic agent SN-38. High-throughput formulation techniques were employed to fabricate LNP by mixing various amounts of am
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11

Gazaro, Wéré Régine. "Plant variety protection: Which system of protection in the member states of OAPI?" World Patent Information 28, no. 2 (2006): 127–31. http://dx.doi.org/10.1016/j.wpi.2005.12.001.

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12

Ngombe, Laurier Yvon. "Audiovisual Work in the Member States of the African Intellectual Property Organization (OAPI)." Journal of World Intellectual Property 9, no. 4 (2006): 445–57. http://dx.doi.org/10.1111/j.1422-2213.2006.00286.x.

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13

Quansah, Anthony, Zhirong Xiao, and Tresor Ntaryamira. "Parametric Investigation of Plane Frame Structure Using Excel Vba And Sap2000 oapi Based Programming." International Journal of Engineering Research and Applications 07, no. 07 (2017): 14–23. http://dx.doi.org/10.9790/9622-0707091423.

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14

Hula, Ibnu Rawandhy N., Adimawati Helingo, Sitti Nur Adawiyah Jassin, and Suharia Sarif. "Transcription of Pegon Gorontalo Arabic Orthography, Malay and Arabic Standard: A Contraceptive Linguistic Analysis." `A Jamiy : Jurnal Bahasa dan Sastra Arab 11, no. 2 (2022): 322. http://dx.doi.org/10.31314/ajamiy.11.2.322-341.2022.

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Penelitian ini bertujuan untuk mentranskripsi tuturan yang berbentuk bunyi ke dalam bentuk tulisan Ortografi Arab Pegon Gorontalo (OAPG) dan membandingkannya dengan Ortografi Arab Pegon Melayu (OAPM) dan Ortografi Arab standar (OAS). Metode penelitian yang digunakan adalah kualitatif deskriptif dengan pendekatan linguistic kontrastif. Data dikumpulkan berbentuk dokumen manuskrip dari kitab dikili yang berasal dari empat kabupaten di Provinsi Gorontalo. Data OAPG dianalisis dengan menggunakan teknik rekam catat, kemudian membandingkannya dengan OAPM dan OAS. Hasil penelitian ini menunjukkan bah
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15

Pisani, Francesco, Laura Simone, Maria Mola, et al. "Host-Cell Type Dependent Features of Recombinant Human Aquaporin-4 Orthogonal Arrays of Particles—New Insights for Structural and Functional Studies." Cells 8, no. 2 (2019): 119. http://dx.doi.org/10.3390/cells8020119.

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The CNS plasma-membrane water channel aquaporin-4 (AQP4) is expressed as two major isoforms able to aggregate into supramolecular assemblies known as ‘orthogonal arrays of particles’ (OAPs). OAP subnanometric features are largely unknown mainly because a method for the expression, isolation, and crystallization of integral human OAPs has not been developed. Here, the human OAP-forming isoform M23-AQP4 was expressed in insect and mammalian cell lines and AQP4 and OAP features evaluated. Native size exclusion chromatography was employed to isolate and analyze authentically folded OAPs, and neuro
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16

Tankoano, Amadou. "La protection des obtentions végétales dans les états menbres de l'organisation africaine de la propriété intellectuelle(OAPI)." Revue internationale de droit économique XVII, 1, no. 1 (2003): 103. http://dx.doi.org/10.3917/ride.171.0103.

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17

Cucuzza, Raffaele, Marco Martino Rosso, Angelo Aloisio, Jonathan Melchiorre, Mario Lo Giudice, and Giuseppe Carlo Marano. "Size and Shape Optimization of a Guyed Mast Structure under Wind, Ice and Seismic Loading." Applied Sciences 12, no. 10 (2022): 4875. http://dx.doi.org/10.3390/app12104875.

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This paper discusses the size and shape optimization of a guyed radio mast for radiocommunications. The considered structure represents a widely industrial solution due to the recent spread of 5G and 6G mobile networks. The guyed radio mast was modeled with the finite element software SAP2000 and optimized through a genetic optimization algorithm (GA). The optimization exploits the open application programming interfaces (OAPI) SAP2000-Matlab. Static and dynamic analyses were carried out to provide realistic design scenarios of the mast structure. The authors considered the action of wind, ice
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18

Vladkova, Todorka G., Alexander Chr Alaminov, and Milka G. Pankova. "A Study of the Interactions Between Oligoamidephosphate (OAPh) and Curatives in a Sulphenamide-Accelerated Sulphur Vulcanizing System." Journal of Polymer Engineering 19, no. 2 (1999): 95–108. http://dx.doi.org/10.1515/polyeng-1999-0203.

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Abstract The possible interactions between oligoamidephosphate (OAPli) and the curatives of a sulphenamide-accelerated sulphur vulcanizing system were studied by differential scanning calorimetry, IR-spectroscopy, and X-ray analysis. The interactions in double mixtures were between OAPh and zinc oxide (ZnO) and OAPh and sulphur. The OAPh/ZnO interaction that starts at room temperature seems to be the key for understanding the peculiarities of sulphenamide-accelerated sulphur vulcanization in the presence of OAPh.
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19

Prakash, Jay, and Ayşe T. Daloglu. "Teaching-learning-based optimization of unbraced steel frames with semi-rigid connections and column bases." Journal of Structural Engineering & Applied Mechanics 6, no. 1 (2023): 27–44. http://dx.doi.org/10.31462/jseam.2023.01027044.

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The teaching-learning optimization (TLBO) technique is applied to unbraced steel frames with semi-rigid beam-to-column connections and semi-rigid column-to-base connections. The algorithm for design produces optimized steel frames by choosing appropriate sections from a set of standard steel sections. These standard steel sections, including wide-flange profiles (W), are provided by the American Institute of Steel Construction (AISC). The first example is subjected to the displacement, inter-story drift, and stress constraints of AISC-Load and Resistance Factor Design (LRFD) regulations. In ad
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20

Dinh-Cong, D., T. Nguyen-Thoi, and Duc T. Nguyen. "A FE model updating technique based on SAP2000-OAPI and enhanced SOS algorithm for damage assessment of full-scale structures." Applied Soft Computing 89 (April 2020): 106100. http://dx.doi.org/10.1016/j.asoc.2020.106100.

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21

Bello, Ibrahim. "L’appréciation du risque de confusion à l’épreuve du principe de la territorialité des droits de propriété industrielle dans l’espace OAPI." Uniform Law Review 27, no. 3 (2022): 441–59. http://dx.doi.org/10.1093/ulr/unac026.

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Résumé La délimitation du cadre géographique dans lequel le risque de confusion s’apprécie est consubstantielle de la protection des droits querellés dans ledit cadre. C’est l’application du principe de la territorialité des droits qui veut qu’un droit n’est garanti que dans les limites du territoire du pays dans lequel la protection a été acquise. Dès lors, il était récurrent que des personnes exploitant des marques se trouvent démunies de tout argument dans les pays où celles – ci avaient été abusivement déposées. L’application difficultueuse de ce principe a donné l’occasion à une doctrine
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Daloglu, Ayse T., Musa Artar, Korhan Ozgan, and Ali İ. Karakas. "Optimum Design of Braced Steel Space Frames including Soil-Structure Interaction via Teaching-Learning-Based Optimization and Harmony Search Algorithms." Advances in Civil Engineering 2018 (2018): 1–16. http://dx.doi.org/10.1155/2018/3854620.

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Optimum design of braced steel space frames including soil-structure interaction is studied by using harmony search (HS) and teaching-learning-based optimization (TLBO) algorithms. A three-parameter elastic foundation model is used to incorporate the soil-structure interaction effect. A 10-storey braced steel space frame example taken from literature is investigated according to four different bracing types for the cases with/without soil-structure interaction. X, V, Z, and eccentric V-shaped bracing types are considered in the study. Optimum solutions of examples are carried out by a computer
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Gnintedem, Patrick Juvet Lowé. "Les organisations régionales africaines de la propriété intellectuelle et l’accès aux médicaments dans des situations de pandémie." African Yearbook of International Law Online / Annuaire Africain de droit international Online 24, no. 1 (2019): 88–123. http://dx.doi.org/10.1163/22116176_02401007.

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Souvent frappée par des crises sanitaires, l’Afrique est constamment confrontée aux difficultés d’accès aux médicaments résultant de la protection des droits de propriété intellectuelle (DPI). L’avènement de la pandémie de Covid-19 rappelle des débats devenus vifs ces trois dernières décennies, relativement au sort à réserver aux DPI couvrant les médicaments nécessaires à la prise en charge des populations. À cet effet, les organisations régionales africaines de propriété intellectuelle, dans le cadre de l’Union africaine, mais surtout de l’Organisation régionale africaine de la propriété inte
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Hao, W., V. S. Molchanov, Yu M. Chesnokov, P. R. Podlesnyi, and O. E. Philippova. "Effect of Electrostatic Interactions in Wormlike Micelles of Surfactants Based on Betaine and Charged Tertiary Amine with the Same Hydrophobic Groups." Colloid Journal 86, no. 2 (2024): 306–14. http://dx.doi.org/10.1134/s1061933x23601373.

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Abstract The viscoelastic properties and structure of solutions of mixed wormlike micelles based on a zwitterionic surfactant, oleylamidopropyldimethylcarboxybetaine (OAPB), and positively charged oleylamidopropyldimethylamine (OAPA) have been studied at different ratios between the components. At a small fraction of the cationic surfactant, OAPA, the solution exhibits viscoelastic properties characteristic of semidiluted solutions of entangled wormlike micelles, the presence of which has been confirmed by cryogenic electron microscopy data. It has been found that, as the molar fraction of the
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Domingo, Ephraim Viernes. "Coping strategies in oral academic presentations of international undergraduate students in a Philippine university: a small-case study." Language Learning in Higher Education 11, no. 1 (2021): 93–113. http://dx.doi.org/10.1515/cercles-2021-2011.

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Abstract Higher education students are increasingly becoming aware of the importance of being successful in oral academic presentations (OAP) in their academic endeavors. For English as a second language students in English-medium institutions, it also provides them with opportunities for language socialization. However, succeeding in the delivery of an OAP comes with various challenges emerging from linguistic and psychological factors. This small-case study explores OAPs as an oral academic socialization activity by documenting the strategies that 13 international undergraduate students in a
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Kholidah, Nurul. "Pengaruh Temperatur terhadap Persentase Yield pada Proses Perengkahan Katalitik Sampah Plastik menjadi Bahan Bakar Cair." ALKIMIA : Jurnal Ilmu Kimia dan Terapan 2, no. 1 (2018): 28–33. http://dx.doi.org/10.19109/alkimia.v2i1.2259.

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Peningkatan konsumsi energi dan peningkatan timbulan sampah plastik merupakan dua permasalahan besar yang muncul seiring dengan pertumbuhan ekonomi dan pertambahan penduduk. Salah satu jenis sampah plastik polystyrene yang dapat diolah menjadi bahan bakar cair dengan proses perengkahan adalah styrofoam. Pada penelitian ini, proses perengkahan sampah plastik polystyrene dilakukan dengan proses perengkahan katalitik dengan menggunakan katalis Al2O3. Penelitian ini bertujuan untuk mengetahui pengaruh temperatur terhadap persentase yield produk dan karakteristik produk yang dihasilkan dari proses
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Wang, Dejiang, and Haojie Lu. "Development of a BIM Platform for the Design of Single-Story Steel Structure Factories." Buildings 14, no. 3 (2024): 747. http://dx.doi.org/10.3390/buildings14030747.

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Traditional design methods for single-story steel structure factories are characterized by low levels of digitalization and high error rates. To deal with these problems, a building information modeling (BIM) platform for the design of single-story steel structure factories was developed in this paper, which aimed to improve the design process for such structures. Firstly, the components of the factory were categorized, and the Revit API was employed to automate the generation of the BIM model. Load applications and combinations were then established using the Revit API, which relied on a set
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Yang, Yang, Kimberly A. Harris, Danielle L. Widner, and Ronald R. Breaker. "Structure of a bacterial OapB protein with its OLE RNA target gives insights into the architecture of the OLE ribonucleoprotein complex." Proceedings of the National Academy of Sciences 118, no. 9 (2021): e2020393118. http://dx.doi.org/10.1073/pnas.2020393118.

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The OLE (ornate, large, and extremophilic) RNA class is one of the most complex and well-conserved bacterial noncoding RNAs known to exist. This RNA is known to be important for bacterial responses to stress caused by short-chain alcohols, cold, and elevated Mg2+concentrations. These biological functions have been shown to require the formation of a ribonucleoprotein (RNP) complex including at least two protein partners: OLE-associated protein A (OapA) and OLE-associated protein B (OapB). OapB directly binds OLE RNA with high-affinity and specificity and is believed to assist in assembling the
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Widner, Danielle L., Kimberly A. Harris, Lukas Corey, and Ronald R. Breaker. "Bacillus halodurans OapB forms a high-affinity complex with the P13 region of the noncoding RNA OLE." Journal of Biological Chemistry 295, no. 28 (2020): 9326–34. http://dx.doi.org/10.1074/jbc.ra120.012676.

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Noncoding RNAs (ncRNAs) longer than 200 nucleotides are rare in bacteria, likely because bacterial genomes are under strong evolutionary pressures to maintain a small genome size. Of the long ncRNAs unique to bacteria, the OLE (ornate, large, extremophilic) RNA class is among the largest and most structurally complex. OLE RNAs form a ribonucleoprotein (RNP) complex by partnering with at least two proteins, OapA and OapB, that directly bind OLE RNA. The biochemical functions of the OLE RNP complex remain unknown, but are required for proper adaptation to certain environmental stresses, such as
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E.Y.H, Bobobee, Yakanu P.N., Marenya M.O, and Ochanda J.P.O. "THE TEK MECHANICAL CASSAVA HARVESTER DEVELOPMENT IN GHANA – CHALLENGES, OPPORTUNITIES AND PROSPECTS FOR CASSAVA PRODUCTION IN AFRICA." Journal of Engineering in Agriculture and the Environment 5, no. 1 (2019): 20. http://dx.doi.org/10.37017/jeae.v5i1.51.

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The low level of engineering technology inputs into agriculture is a major constraint hindering themodernization of agriculture and food production in many parts of Africa. Cassava (Manihot esculentaCrantz), is a climate resilient crop grown by smallholder farmers in most sub-Saharan Africa countries.Cassava provides dietary carbohydrates for over 800 million people globally. It is also a bio-fuel sourcethat can replace fossil fuels. Africa is not visible in the cassava industrialisation and export marketbecause it depends on over-aged farmers, who use manual tools and traditional production m
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Amalia, Dhea Nurul, Anindya Indrita Putri, Della Agustia Marhani, Putri Vina Amalia, Anwar Muhamad Rizki, and Keryanti Keryanti. "Biogasoline Production from Shallot Skin Waste with KOH-Clay Catalyst to Create Clean Energy." Fluida 16, no. 2 (2023): 85–91. http://dx.doi.org/10.35313/fluida.v16i2.4591.

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Finding alternative fuels to replace fossil fuels has been made easier by the rise in the consumption of fuels like petrol and the fall in the production of national petroleum exploration activities. This research has been prompted using biomass as an alternative fuel. The primary raw material is shallot skin waste because it has enough lignocellulosic content to be used, one of which is to manufacture biogasoline by using the characteristics of petrol E10. A KOH-Clay catalyst is employed in a thermal and catalytic reaction to influence the reaction's pace. Starting with raw material preparati
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Enakrire, Rexwhite Tega, and Joseph M. Ngoaketsi. "Open access practices: roadmap to research paper publications in academic institutions." Library Hi Tech News 37, no. 5 (2020): 13–15. http://dx.doi.org/10.1108/lhtn-01-2020-0003.

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Purpose The purpose of this paper is to investigate open access practices (OAPs): a roadmap to research paper publications in academic institutions. The rationale that necessitates this scenario was the dwindling nature of the inability of researchers and lecturers/academics in African academic institutions to access related materials in their subject areas, while also advancing effort to publish their research papers in open access. Design/methodology/approach This paper applied a qualitative research approach, in which literature was harvested from Web of Science for developing and writing t
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Cunningham, Jessica, Shawn Binkley, Tanya Uritsky, et al. "168. Syndrome-Based Analysis of Oral Antimicrobial Stewardship Opportunities at Hospital Discharge." Open Forum Infectious Diseases 8, Supplement_1 (2021): S193—S194. http://dx.doi.org/10.1093/ofid/ofab466.370.

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Abstract Background Suboptimal oral antibiotic prescriptions (OAPs) are prevalent at discharge and contribute to treatment failure, resistance, toxicity, and excess costs. Syndrome-specific prescribing patterns have not been widely described at discharge, nor have specific reasons for excessive treatment durations (the most commonly cited prescribing error). Methods Retrospective cohort of patients discharged from a general medicine service at an academic hospital with ≥1 OAP for urinary tract infection (UTI), skin and soft tissue infection (SSTI), or lower respiratory tract infection (LRTI).
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Verbavatz, J. M., T. Ma, R. Gobin, and A. S. Verkman. "Absence of orthogonal arrays in kidney, brain and muscle from transgenic knockout mice lacking water channel aquaporin-4." Journal of Cell Science 110, no. 22 (1997): 2855–60. http://dx.doi.org/10.1242/jcs.110.22.2855.

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Freeze-fracture electron microscopy (FFEM) of kidney collecting duct, muscle, astrocytes in brain, and other mammalian tissues has revealed regular square arrays of intramembrane particles called orthogonal arrays of particles (OAPs). Their possible role in membrane structure and transport have been proposed, and their absence or decrease has been noted in a variety of hereditary and acquired diseases. A transgenic mouse lacking water channel AQP4 was used to show that AQP4 is the OAP protein. FFEM was done on kidney, skeletal muscle, and brain from AQP4 wild-type [+/+], heterozygous [+/−] and
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O'Shea, Sebastian J., Jonathan Crosier, James Dorsey, et al. "Revisiting particle sizing using greyscale optical array probes: evaluation using laboratory experiments and synthetic data." Atmospheric Measurement Techniques 12, no. 6 (2019): 3067–79. http://dx.doi.org/10.5194/amt-12-3067-2019.

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Abstract. In situ observations from research aircraft and instrumented ground sites are important contributions to developing our collective understanding of clouds and are used to inform and validate numerical weather and climate models. Unfortunately, biases in these datasets may be present, which can limit their value. In this paper, we discuss artefacts which may bias data from a widely used family of instrumentation in the field of cloud physics, optical array probes (OAPs). Using laboratory and synthetic datasets, we demonstrate how greyscale analysis can be used to filter data, constrai
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Fitzgerald, Heather M., Jason Shepherd, Hollie Bailey, Mia Berry, Jack Wright, and Maxine Chen. "Characterization and Treatment Goals of Patients on Long-Acting Injectable vs Oral Antipsychotics: Results from a Patient/Caregiver/Psychiatrist Survey." CNS Spectrums 26, no. 2 (2021): 154. http://dx.doi.org/10.1017/s109285292000245x.

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AbstractBackgroundPatient preferences in schizophrenia (SCZ), including identification of key goals and outcomes for treatment and relative importance of certain treatment goals to patients, have been assessed by several studies. However, there continues to be a lack of sufficient evidence on US patient attitudes and perceptions towards treatment goals and pharmacotherapy options in SCZ, especially taking into context long-acting injectable antipsychotics (LAIs) in this disease area. This lack of evidence is further pronounced in caregivers of individuals with SCZ. The objective of this analys
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Zhang, Quanwu, Weixing Shi, and Yanze Wang. "Human-Induced Vibration Control of Floor Structures Using MTMD System Optimized by MATLAB-SAP2000 Interface." Buildings 14, no. 2 (2024): 308. http://dx.doi.org/10.3390/buildings14020308.

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Under human-induced excitations, a floor structure may suffer excessive vibrations due to its large span and low damping ratio. Vertical vibrations, in particular, can become intolerable during resonance events. A tuned mass damper (TMD) is a widely used single-degree-of-freedom dynamic vibration absorber. To enhance the serviceability of a floor structure, a multiple TMD (MTMD) system finds broad application. The parameters of the MTMD must be carefully designed to achieve satisfactory performance. However, existing studies often employ a simplified model of the floor structure with closely s
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Crane, Jonathan M., Chiwah Lam, Andrea Rossi, Tripta Gupta, Jeffrey L. Bennett, and A. S. Verkman. "Binding Affinity and Specificity of Neuromyelitis Optica Autoantibodies to Aquaporin-4 M1/M23 Isoforms and Orthogonal Arrays." Journal of Biological Chemistry 286, no. 18 (2011): 16516–24. http://dx.doi.org/10.1074/jbc.m111.227298.

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Autoantibodies against astrocyte water channel aquaporin-4 (AQP4) are highly specific for the neuroinflammatory disease neuromyelitis optica (NMO). We measured the binding of NMO autoantibodies to AQP4 in human astrocyte-derived U87MG cells expressing M1 and/or M23 AQP4, or M23 mutants that do not form orthogonal array of particles (OAPs). Binding affinity was quantified by two-color fluorescence ratio imaging of cells stained with NMO serum or a recombinant monoclonal NMO autoantibody (NMO-rAb), together with a C terminus anti-AQP4 antibody. NMO-rAb titrations showed binding with dissociation
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Silberstein, Claudia, Richard Bouley, Yan Huang, et al. "Membrane organization and function of M1 and M23 isoforms of aquaporin-4 in epithelial cells." American Journal of Physiology-Renal Physiology 287, no. 3 (2004): F501—F511. http://dx.doi.org/10.1152/ajprenal.00439.2003.

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Aquaporin-4 (AQP4) water channels exist as heterotetramers of M1 and M23 splice variants and appear to be present in orthogonal arrays of intramembraneous particles (OAPs) visualized by freeze-fracture microscopy. We report that AQP4 forms OAPs in rat gastric parietal cells but not in parietal cells from the mouse or kangaroo rat. Furthermore, the organization of principal cell OAPs in Brattleboro rat kidney is perturbed by vasopressin (arginine vasopressin). Membranes of LLC-PK1 cells expressing M23-AQP4 showed large, abundant OAPs, but none were detectable in cells expressing M1-AQP4. Measur
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Kaymakcalan, Marina D., Jenafer Thomas, Kristin Nowakowski, et al. "Clinical pharmacist prescription review and modification for oral antineoplastic medications at an academic medical center." JCO Oncology Practice 19, no. 11_suppl (2023): 64. http://dx.doi.org/10.1200/op.2023.19.11_suppl.64.

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64 Background: Collaboration between oncology providers and pharmacy teams has improved the safety of oral antineoplastic (OA) prescribing, but opportunities remain for improvements in care delivery. To this end, starting in March 1, 2021, the Dana Farber Cancer Institute Specialty Pharmacy implemented a new workflow - clinical verification of new specialty prescriptions by dedicated OA clinical pharmacists (OAPs) prior to prescription processing. To reduce the impact of initial prescription errors on efficiency and safety, one component of clinical verification was to expand the purview of OA
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Jorgačevski, Jernej, Robert Zorec, and Maja Potokar. "Insights into Cell Surface Expression, Supramolecular Organization, and Functions of Aquaporin 4 Isoforms in Astrocytes." Cells 9, no. 12 (2020): 2622. http://dx.doi.org/10.3390/cells9122622.

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Aquaporin 4 (AQP4) is the most abundant water channel in the central nervous system (CNS). Its expression is confined to non-neuronal glial cells, predominantly to astrocytes that represent a heterogeneous glial cell type in the CNS. The membrane of astrocyte processes, which align brain capillaries and pia, is particularly rich in AQP4. Several isoforms of AQP4 have been described; however, only some (AQP4a (M1), AQP4 c (M23), AQP4e, and AQP4ex) have been identified in the plasma membrane assemblies of astrocytes termed orthogonal arrays of particles (OAPs). Intracellular splicing isoforms (A
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Indonesia, Alfath Bagus Panuntun El Nur. "Education and Social Mobility For Orang Asli Papua." PCD Journal 9, no. 2 (2022): 121–47. http://dx.doi.org/10.22146/pcd.v9i2.3313.

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Papuan human resources are complicated due to educational barriers that make it difficult for indigenous Papuans (OAP) to achieve upward social mobility. Many factors have contributed to these educational barriers, including poverty, conflict and war, a lack of teachers, and poor infrastructure. These obstacles should be solved through the main feature of the Special Autonomy Law (SAL), namely the "special autonomy fund". Although these funds have been rolled out in Papua since 2001 to address inequality and improve OAP's human resources, their conditions have not improved significantly. This
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Stump, Trevor A., Leigh Anne Nelson, Yifei Liu, et al. "The effects of concurrent oral paliperidone or risperidone use with paliperidone long-acting injection." Mental Health Clinician 11, no. 1 (2021): 12–18. http://dx.doi.org/10.9740/mhc.2021.01.012.

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Abstract Introduction Dosing recommendations for paliperidone long-acting injectable antipsychotic (LAIA) do not include oral antipsychotic (OAP) overlap; however, OAPs are often given concurrently despite limited evidence describing both the risks and benefits of this practice. Methods A retrospective chart review was conducted in patients initiated on paliperidone palmitate (PP) during a psychiatric hospitalization to compare patients who received OAP overlap versus those who did not. The primary outcome is the proportion of patients who receive prescription claims for benztropine, a medicat
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Zafereo, Mark E., Rodney J. Taylor, and Kevin D. Pereira. "S248 – Supraglottoplasty for Laryngomalacia with Sleep Apnea." Otolaryngology–Head and Neck Surgery 139, no. 2_suppl (2008): P158. http://dx.doi.org/10.1016/j.otohns.2008.05.423.

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Objectives To determine if supraglottoplasty is effective in reversing abnormal respiratory parameters in children with laryngomalacia and obstructive sleep apnea. Methods 10 patients with laryngomalacia and obstructive sleep apnea as documented by polysomnography underwent supraglottoplasty at a tertiary referral children's hospital between 2005 and 2007. Retrospective data collection included age, findings on flexible and rigid endoscopy, type of procedure performed, and postoperative course. The postoperative polysomnographies were reviewed to identify changes in obstructive apnea index (OA
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O'Shea, Sebastian, Jonathan Crosier, James Dorsey, et al. "Characterising optical array particle imaging probes: implications for small-ice-crystal observations." Atmospheric Measurement Techniques 14, no. 3 (2021): 1917–39. http://dx.doi.org/10.5194/amt-14-1917-2021.

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Abstract. The cloud particle concentration, size, and shape data from optical array probes (OAPs) are routinely used to parameterise cloud properties and constrain remote sensing retrievals. This paper characterises the optical response of OAPs using a combination of modelling, laboratory, and field experiments. Significant uncertainties are found to exist with such probes for ice crystal measurements. We describe and test two independent methods to constrain a probe's sample volume that remove the most severely mis-sized particles: (1) greyscale image analysis and (2) co-location using stereo
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Kirk, Johnathan P., and Gordon A. Cromley. "Assimilating Weather Data into a Digital Event Gazetteer of Airborne Parachute Operations during the French Indochina War." Weather, Climate, and Society 10, no. 1 (2017): 19–34. http://dx.doi.org/10.1175/wcas-d-17-0016.1.

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Abstract Modern datasets cataloging historical events, known as digital event gazetteers, feature spatiotemporal data regarding events that enable analysis through parameters including location and other descriptive information of those events. Weather and climate data represent two dimensions of spatiotemporal information, which can enhance understanding of historical events. A recently published digital event gazetteer of airborne parachute operations [opérations aéroportées (OAPs)] during and prior to the French Indochina War, spanning from 1945 to 1954, represents an opportunity to associa
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Wicaksono, Wicaksono, Pudji Permadi, Utjok W. R. Siagian, and Tjokorde Walmiki Samadhi. "Very High Temperature Laboratory CO2 Injection." Modern Applied Science 11, no. 12 (2017): 58. http://dx.doi.org/10.5539/mas.v11n12p58.

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Carbon dioxide (CO2) injection is the most promising technique to enhance the recovery of high gravity oil with the existing oil price situation. Even though, challenges still exist for thick and heterogeneous reservoirs at very high temperature. The problems faced in such reservoirs are low displacement efficiency and very high injection pressure requirement for a miscible displacement. The effort being done by researchers to overcome the situations is the use of silica nanoparticle as an agent to form CO2-silica nanoparticle foam. Currently, the related literature shows that CO2 miscible dis
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Rubio, Jose M., Heidi Taipale, Christoph U. Correll, Antti Tanskanen, John M. Kane, and Jari Tiihonen. "Psychosis breakthrough on antipsychotic maintenance: results from a nationwide study." Psychological Medicine 50, no. 8 (2019): 1356–67. http://dx.doi.org/10.1017/s0033291719001296.

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AbstractBackgroundThere is uncertainty about the incidence of breakthrough psychosis in treatment adherent patients, and the role that factors, such as cumulative antipsychotic exposure, play in this phenomenon.MethodsIn a nationwide cohort of individuals treated for schizophrenia-spectrum disorders in Finland between 1 January 1996 and 31 December 2015, ‘Breakthrough Psychosis on Antipsychotic Maintenance Medication’ (BAMM) was defined as hospitalization for psychosis despite ongoing continuous treatment with long-acting injectable antipsychotics (LAIs) or oral antipsychotics (OAPs) for ⩾8 we
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Prami, Tuire, Houssem Khanfir, Pål Hasvold, Eeva Reissell, Juhani Airaksinen, and Ville Kytö. "Concomitant use of drugs known to cause interactions with oral antiplatelets—polypharmacy in acute coronary syndrome outpatients in Finland." European Journal of Clinical Pharmacology 76, no. 2 (2019): 257–65. http://dx.doi.org/10.1007/s00228-019-02777-z.

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Abstract Purpose Use of oral antiplatelets (OAPs) is essential for preventing thrombotic events in patients with acute coronary syndrome (ACS). Effects of clopidogrel, prasugrel, and ticagrelor may be enhanced due to pharmacodynamic interactions, but as CYP substrates, they are prone to pharmacokinetic interactions too. The aim was to study polypharmacy in ACS patients following hospital discharge. Methods This observational drug utilization study linked patient-level data from nationwide registers. The study population consisted of adult ACS patients discharged from Finnish hospitals in 2009–
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Chen, Maxine, Jason Shepherd, Hollie Bailey, Jack Wright, and Heather M. Fitzgerald. "Analysis of Treatment Goals for Patients with Schizophrenia: A US Survey of Psychiatrists, Patients with SCZ and Caregivers." CNS Spectrums 26, no. 2 (2021): 158. http://dx.doi.org/10.1017/s1092852920002539.

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AbstractObjectivesObjectives for this survey are to determine similarities or differences in treatment goals reported by psychiatrists, patients with schizophrenia (SCZ) and caregivers in the US, as well as whether goals differed by patients currently on an oral antipsychotic (OAP) or long-acting injectable (LAI), and whether goals differed by age.MethodsThis was a real-world, cross-sectional survey of US psychiatrists, patients =18 years old diagnosed with SCZ, and caregivers. Data was collected using the Disease Specific Programme (DSP) methodology. Psychiatrists (n=120) completed detailed r
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