Log in

Relevant bibliographies by topics / Obesity – Genetic aspects / Journal articles

To see the other types of publications on this topic, follow the link: Obesity – Genetic aspects.

Journal articles on the topic 'Obesity – Genetic aspects'

Author: Grafiati

Published: 4 June 2021

Last updated: 20 February 2023

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the top 50 journal articles for your research on the topic 'Obesity – Genetic aspects.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Browse journal articles on a wide variety of disciplines and organise your bibliography correctly.

1

BOUCHARD, CLAUDE, and LOUIS PÉRUSSE. "Genetic Aspects of Obesity." Annals of the New York Academy of Sciences 699, no. 1 Prevention an (1993): 26–35. http://dx.doi.org/10.1111/j.1749-6632.1993.tb18834.x.

Full text

APA, Harvard, Vancouver, ISO, and other styles

2

Johnson, P. R., M. R. C. Greenwood, B. A. Horwitz, and J. S. Stern. "Animal Models of Obesity: Genetic Aspects." Annual Review of Nutrition 11, no. 1 (1991): 325–53. http://dx.doi.org/10.1146/annurev.nu.11.070191.001545.

Full text

APA, Harvard, Vancouver, ISO, and other styles

3

Barness, Lewis A., John M. Opitz, and Enid Gilbert-Barness. "Obesity: Genetic, molecular, and environmental aspects." American Journal of Medical Genetics Part A 143A, no. 24 (2007): 3016–34. http://dx.doi.org/10.1002/ajmg.a.32035.

Full text

APA, Harvard, Vancouver, ISO, and other styles

4

Sadaf Farooqi, I. "Genetic and hereditary aspects of childhood obesity." Best Practice & Research Clinical Endocrinology & Metabolism 19, no. 3 (2005): 359–74. http://dx.doi.org/10.1016/j.beem.2005.04.004.

Full text

APA, Harvard, Vancouver, ISO, and other styles

5

Tyrtova, Ludmila Viktorovna, Natalja Vladimirovna Parshina, and Kristina Vladimirovna Skobeleva. "Genetic and Epigenetic Aspects of Obessity and Metabolic Syndrom in Child." Pediatrician (St. Petersburg) 4, no. 2 (2013): 3–11. http://dx.doi.org/10.17816/ped423-11.

Full text

Abstract:

In a review article analyzes the role of heredity in the occurrence of obesity and metabolic syndrome. Debut of hyperphagia and severe obesity from early childhood are typical for monogenic forms and syndromes. Many nonspecific candidate-genes in combination form a polygenic basis for the accumulation of excess body fat, especially under the influence of irrational diet and low physical activity. Examined the role of epigenetic factors in the individual genetic variants in fetus, predisposing to obesity and metabolic syndrome after birth. Discuss the possibilities of early prevention of obesit

APA, Harvard, Vancouver, ISO, and other styles

6

Marklová, Eliška. "Genetic Aspects of Diabetes Mellitus." Acta Medica (Hradec Kralove, Czech Republic) 44, no. 1 (2001): 3–6. http://dx.doi.org/10.14712/18059694.2019.79.

Full text

Abstract:

Practically all types of diabetes mellitus (DM) result from complex interactions of genetic and environmental factors. Multifactorial and polygenic Type 1 DM is strongly influenced by genes controlling the immune system, mainly HLA-DQ and DR. In addition to this, many other predisposition loci, interacting with each other, have some influence on susceptibility to DM. Heterogeneous Type 2 DM, accounting for about 85 % of all diabetic patients, is supposed to be induced by multiple genes defects involved in insulin action and/or insulin secretion. Other genetically influenced traits like obesity

APA, Harvard, Vancouver, ISO, and other styles

7

Clément, Karine, and Arnaud Basdevant. "Pathophysiological Aspects of Human Obesity – What We Know in 2010." European Endocrinology 06 (2010): 10. http://dx.doi.org/10.17925/ee.2010.06.00.10.

Full text

Abstract:

Obesity, a disease of both developed and developing countries, is spreading at an epidemic pace. According to the World Health Organization (WHO), obesity is defined as an increase or abnormal accumulation of body fat mass to the extent that an individual’s health will be negatively affected. Overweight (i.e. body mass index [BMI] >25kg/m2) is considered to be a significant risk factor for the development of many chronic diseases. Environmental, behavioural, genetic and biological factors interact to cause obesity, which can be viewed as a set of phenotypes that evolve over time in stages t

APA, Harvard, Vancouver, ISO, and other styles

8

Oral, Onur, George Nomikos, and Nikitas Nomikos. "Evaluation of Genetics of Obesity and MC4R Deficiency: A Gene-oriented Approach to Obesity." Journal of Endocrinology Research 3, no. 1 (2021): 41. http://dx.doi.org/10.30564/jer.v3i1.2977.

Full text

Abstract:

Obesity is a multifactorial and complex health problem that is affected by several factors including genetic, environmental, social,behavioural, and biological aspects. Even though the influence of other environmental and behavioural factors such as sedentary lifestyle, high-calorie nutritional intake, and the inadequate expenditure of energy are acknowledged as important aspects that cause obesity, the issue of inheritance is indisputable. The study aims to investigate the effects of inheritance on obesity and examine how understanding and detecting genetic reasons behind obesity may benefit

APA, Harvard, Vancouver, ISO, and other styles

9

Kozak, LP, and RA Koza. "Mitochondrial uncoupling proteins and obesity: Molecular and genetic aspects of UCP1." International Journal of Obesity 23, S6 (1999): S33—S37. http://dx.doi.org/10.1038/sj.ijo.0800941.

Full text

APA, Harvard, Vancouver, ISO, and other styles

10

Kireeva, Victoria Vladimirovna, Svetlana Aleksandrovna Lepekhova, Lyubov Nazirovna Mansurova, and Saryuna Chingisovna Dugarova. "EPIGENETIC AND MOLECULAR AND GENETIC ASPECTS OF OBESITY AS A RISK FACTOR OF CARDIOVASCULAR CATASTROPHES." EurasianUnionScientists 5, no. 7(76) (2020): 39–44. http://dx.doi.org/10.31618/esu.2413-9335.2020.5.76.926.

Full text

Abstract:

The review provides current information of obesity in the pathogenesis of cardiovascular diseases the leading cause of death. Showing the genetic basis for the development of metabolic syndrome. The question of external influence on genes, mutations in which lead to the development of obesity is determined. The question of the possible role of exogenous destroyers in the development of metabolic syndrome is considered. The main genes involved in monogenic and polygenic variants of obesity are identified. The review shows that to prevent the development of metabolic syndrome, it is necessary to

APA, Harvard, Vancouver, ISO, and other styles

11

Timasheva, Ya R., Zh R. Balkhiyarova, and O. V. Kochetova. "Current state of the obesity research: genetic aspects, the role of microbiome, and susceptibility to COVID-19." Problems of Endocrinology 67, no. 4 (2021): 20–35. http://dx.doi.org/10.14341/probl12775.

Full text

Abstract:

Obesity affects over 700 million people worldwide and its prevalence keeps growing steadily. The problem is particularly relevant due to the increased risk of COVID-19 complications and mortality in obese patients. Obesity prevalence increase is often associated with the influence of environmental and behavioural factors, leading to stigmatization of people with obesity due to beliefs that their problems are caused by poor lifestyle choices. However, hereditary predisposition to obesity has been established, likely polygenic in nature. Morbid obesity can result from rare mutations having a sig

APA, Harvard, Vancouver, ISO, and other styles

12

Уксуменко, А., A. Uksumenko, Марина Антонюк, and Marina Antonyuk. "PATHOGENETIC ASPECTS OF THE PHENOTYPE OF BRONCHIAL ASTHMA ASSOCIATED WITH OBESITY." Bulletin physiology and pathology of respiration 1, no. 71 (2019): 112–19. http://dx.doi.org/10.12737/article_5c89ac3a1c1ac3.25721118.

Full text

Abstract:

Currently, in parallel with the increase in the prevalence of asthma, there is an increase in the number of obese patients. The results of numerous studies indicate that the asthma phenotype in combination with obesity has well-defined clinical features – a more severe course with frequent exacerbations and reduced control of the disease. The article considers the main pathogenetic mechanisms that determine the development of the asthma phenotype in combination with obesity. The influence of excess adipose tissue in the chest on respiratory mechanics, the correlation of gastroesophageal reflux

APA, Harvard, Vancouver, ISO, and other styles

13

Clément, Karine. "Genetics of human obesity." Proceedings of the Nutrition Society 64, no. 2 (2005): 133–42. http://dx.doi.org/10.1079/pns2005416.

Full text

Abstract:

The rapid development of new concepts and tools has led to a change in the way in which researchers carry out nutrition-related research. Obesity is determined by the interaction between predisposing genetic and environmental aspects, but at present the gene–gene and gene–environment interactions contributing to the development of this complex disease cannot be analysed in detail. The purpose of the present paper is to provide some examples of the knowledge that is available in the field of obesity genetics, and also the new strategies being developed that are aimed at studying the relative co

APA, Harvard, Vancouver, ISO, and other styles

14

Bogomolov, Pavel O., Kseniya Yu Kokina, Aleksander Yu Mayorov, and Ekaterina E. Mishina. "Genetic Aspects of Non-Alcoholic Fatty Liver Disease." Current pediatrics 17, no. 6 (2019): 442–48. http://dx.doi.org/10.15690/vsp.v17i6.1974.

Full text

Abstract:

Non-alcoholic fatty liver disease (NAFLD) is the most commonly diagnosed hepatopathy. There is an increase in the incidence of NAFLD in the structure of liver diseases in children and adolescents, which is directly related to the increasing prevalence of obesity. The spectrum of liver tissue changes in NAFLD ranges from benign hepatocellular steatosis to non-alcoholic steatohepatitis (NASH), fibrosis, cirrhosis of the liver, and hepatocellular carcinoma. With the increasing prevalence of NAFLD in children, we can expect an increase in the incidence of adverse outcomes among people of working a

APA, Harvard, Vancouver, ISO, and other styles

15

Thibault, Louise, Stephen C. Woods, and Margriet S. Westerterp-Plantenga. "The utility of animal models of human energy homeostasis." British Journal of Nutrition 92, S1 (2004): S41—S45. http://dx.doi.org/10.1079/bjn20041141.

Full text

Abstract:

The prevalence of obesity among adults and children has increased steadily over the last few years worldwide, reaching epidemic proportions. Particularly alarming is the link between obesity and the development of chronic disorders such as heart disease, type 2 diabetes, hypertension and some cancers (Bjorntorp, 1997). Environmental causes of obesity are thought to include a sedentary lifestyle and an abundance of highly palatable energy-dense foods (Hill et al. 2003). Genetic factors also contribute to susceptibility to obesity, although the genetic basis of most human obesities is thought to

APA, Harvard, Vancouver, ISO, and other styles

16

Barak, Yaacov, and Suyeon Kim. "Genetic Manipulations of PPARs: Effects on Obesity and Metabolic Disease." PPAR Research 2007 (2007): 1–12. http://dx.doi.org/10.1155/2007/12781.

Full text

Abstract:

The interest in genetic manipulations of PPARs is as old as their discovery as receptors of ligands with beneficial clinical activities. Considering the effects of PPAR ligands on critical aspects of systemic physiology, including obesity, lipid metabolism, insulin resistance, and diabetes, gene knockout (KO) in mice is the ideal platform for both hypothesis testing and discovery of new PPAR functions in vivo. With the fervent pursuit of the magic bullet to eradicate the obesity epidemic, special emphasis has been placed on the impacts of PPARs on obesity and its associated diseases. As detail

APA, Harvard, Vancouver, ISO, and other styles

17

Gutiérrez-Cuevas, Jorge, Silvia Lucano-Landeros, Daniel López-Cifuentes, Arturo Santos, and Juan Armendariz-Borunda. "Epidemiologic, Genetic, Pathogenic, Metabolic, Epigenetic Aspects Involved in NASH-HCC: Current Therapeutic Strategies." Cancers 15, no. 1 (2022): 23. http://dx.doi.org/10.3390/cancers15010023.

Full text

Abstract:

Hepatocellular carcinoma (HCC) is the most common primary liver cancer and is the sixth most frequent cancer in the world, being the third cause of cancer-related deaths. Nonalcoholic steatohepatitis (NASH) is characterized by fatty infiltration, oxidative stress and necroinflammation of the liver, with or without fibrosis, which can progress to advanced liver fibrosis, cirrhosis and HCC. Obesity, metabolic syndrome, insulin resistance, and diabetes exacerbates the course of NASH, which elevate the risk of HCC. The growing prevalence of obesity are related with increasing incidence of NASH, wh

APA, Harvard, Vancouver, ISO, and other styles

18

Precenzano, Francesco, Daniela Smirni, Luigi Vetri, et al. "Childhood Obesity and Maternal Personality Traits: A New Point of View on Obesity Behavioural Aspects." Pediatric Reports 13, no. 3 (2021): 538–45. http://dx.doi.org/10.3390/pediatric13030063.

Full text

Abstract:

The epidemic spread of childhood obesity in Western society has interested many researchers, who agree in defining it as a multifactorial disease in which not only eating habits and sedentary lifestyle play a role, but also genetic predisposition. The aim of this study was to analyze the personality profile of a group of mothers of children with obesity and to compare this profile to that of a group of mothers of children without obesity. A total of 258 mothers participated in the study (126 mothers of children with obesity and 132 mothers of children without obesity). Weight and height were m

APA, Harvard, Vancouver, ISO, and other styles

19

Kadykova, O. I. "GENETIC ASPECTS OF DEVELOPMENT AND PROGRESSION OF CONGESTIVE HEART FAILURE IN PATIENTS WITH ISCHEMIC HEART DISEASE AND OBESITY∗." Problems of Endocrine Pathology 57, no. 3 (2016): 17–21. http://dx.doi.org/10.21856/j-pep.2016.3.02.

Full text

Abstract:

In this article elucidated the influence of allelic polymorphism of Gln27Glu of β2-adrenoceptors gene on patients that have coronary heart disease and obesity on the expansion and progression of congestive heart failure and left ventricular systolic dysfunction by surveying 222 patients. Presence of C allel of polymorphous locus Gln27Glu of β2-adrenoreceptors gene in patients with ischemic heart disease and concomitant obesity was associated with decreased risk of development of congestive heart failure (p < 0.05). The obtained data shown the absence of influence of polymorphous variants of

APA, Harvard, Vancouver, ISO, and other styles

20

STĂNESCU, Ana Maria Alexandra, Ioana Veronica GRĂJDEANU, Anca Angela SIMIONESCU, and Mira FLOREA. "Essential clinical and diagnostic aspects in pediatric psoriasis." Romanian Journal of Medical Practice 16, S4 (2021): 50–53. http://dx.doi.org/10.37897/rjmp.2021.s4.11.

Full text

Abstract:

Psoriasis is a chronic, immune-mediated, inflammatory disease of the skin. The quality of life is significantly affected, being characterized by relapses, remissions and the presence of comorbidities associated with psoriasis. Several factors are implicated in the onset of psoriasis in children, including: genetic factors, environmental factors, psychosocial stress, obesity, trauma, skin irritation, use of certain drugs such as lithium, β-adrenergic antagonists and necrosis factor inhibitors. (TNF), the presence of Crohn's disease or juvenile rheumatoid arthritis. Psoriasis is a burden for the

APA, Harvard, Vancouver, ISO, and other styles

21

Genovesi, Simonetta, and Gianfranco Parati. "Cardiovascular Risk in Children: Focus on Pathophysiological Aspects." International Journal of Molecular Sciences 21, no. 18 (2020): 6612. http://dx.doi.org/10.3390/ijms21186612.

Full text

Abstract:

Cardiovascular diseases are the leading cause of death, disability, and health care costs in industrialized countries. In general, cardiovascular diseases occur in adulthood, but cardiovascular damage, including stiffening of the arteries, begins very early. Already in the first decade of life, alterations that will favor the formation of atherosclerotic plaques may be present. Cardiovascular risk factors, associated with genetic predisposition, may trigger a sequence of pathophysiological changes which are associated with the progression of the atherosclerosis process. In this frame, the role

APA, Harvard, Vancouver, ISO, and other styles

22

Denou, Emmanuel, Katarina Marcinko, Michael G. Surette, Gregory R. Steinberg, and Jonathan D. Schertzer. "High-intensity exercise training increases the diversity and metabolic capacity of the mouse distal gut microbiota during diet-induced obesity." American Journal of Physiology-Endocrinology and Metabolism 310, no. 11 (2016): E982—E993. http://dx.doi.org/10.1152/ajpendo.00537.2015.

Full text

Abstract:

Diet and exercise underpin the risk of obesity-related metabolic disease. Diet alters the gut microbiota, which contributes to aspects of metabolic disease during obesity. Repeated exercise provides metabolic benefits during obesity. We assessed whether exercise could oppose changes in the taxonomic and predicted metagenomic characteristics of the gut microbiota during diet-induced obesity. We hypothesized that high-intensity interval training (HIIT) would counteract high-fat diet (HFD)-induced changes in the microbiota without altering obesity in mice. Compared with chow-fed mice, an obesity-

APA, Harvard, Vancouver, ISO, and other styles

23

Owen, J. B. "Genetic aspects of appetite and feed choice in animals." Journal of Agricultural Science 119, no. 2 (1992): 151–55. http://dx.doi.org/10.1017/s0021859600014052.

Full text

Abstract:

Body composition in wild animals is regulated within a band that encompasses variations due to seasonal food supply and physiological state (e.g. that of the reproducing, lactating female and the growing juvenile). This body composition is characteristic of the genotype and is notable for the avoidance of obesity (Pitts & Bullard 1968). Urgent behavioural responses are also invoked to minimize weight loss. Figure 1 illustrates this homeostasis diagrammatically for the non-lactating, mature animal.In this integrated complex, both food intake (quantity) and diet choice (quality) play a major

APA, Harvard, Vancouver, ISO, and other styles

24

Suter, Paolo M. "Alcohol, nutrition and health maintenance: selected aspects." Proceedings of the Nutrition Society 63, no. 1 (2004): 81–88. http://dx.doi.org/10.1079/pns2003326.

Full text

Abstract:

In view of the developments in health care relating to the increased prevalence and incidence of chronic diseases and the continuing increase in health-care expenditure, more attention should be paid to health maintenance and disease prevention. Any strategy that can influence health maintenance is of interest, especially lifestyle factors such as nutrition, exercise or stress control. Alcohol has an important place in the daily life of many healthy as well as sick individuals. Alcohol has three major characteristics; it is a nutrient (energy source), a psycho-active drug and a toxin. Each con

APA, Harvard, Vancouver, ISO, and other styles

25

Rand Abdulateef Abdullah. "Review of literature: Etiology of obesity, risk factors, and the role of genetics." GSC Biological and Pharmaceutical Sciences 21, no. 2 (2022): 197–201. http://dx.doi.org/10.30574/gscbps.2022.21.2.0443.

Full text

Abstract:

Obesity is considered one of the global most significant public problem as it has been associated with different diseases and even death. It is an excess accumulation of fat in the body as a result of increase calorie intake compared to energy expenditure. It is considered as multifactorial condition as many factors play role in its occurrence including genetic susceptibility, external environmental factors, individual attitude. The exact etiology of obesity is intermingled with different factors and nowadays because of development of different aspects of life, sedentary life style dominates t

APA, Harvard, Vancouver, ISO, and other styles

26

Hedström, Anna Karin, Nicole Brenner, Julia Butt, et al. "Overweight/obesity in young adulthood interacts with aspects of EBV infection in MS etiology." Neurology - Neuroimmunology Neuroinflammation 8, no. 1 (2020): e912. http://dx.doi.org/10.1212/nxi.0000000000000912.

Full text

Abstract:

ObjectiveBecause obesity affects the cellular immune response to infections, we aimed to investigate whether high body mass index (BMI) in young adulthood and high Epstein-Barr nuclear antigen 1 (EBNA-1) antibody levels interact with regard to MS risk. We also aimed at exploring potential 3-way interactions between BMI at age 20 years, aspects of Epstein-Barr virus (EBV) infection (high EBNA-1 antibody levels and infectious mononucleosis [IM] history, respectively) and the human leukocyte antigen (HLA)-DRB1*15:01 allele.MethodsUsing Swedish population-based case-control studies (5,460 cases an

APA, Harvard, Vancouver, ISO, and other styles

27

Elena, Grechi, Cammarata Bruna, Mariani Benedetta, Di Candia Stefania, and Chiumello Giuseppe. "Prader-Willi Syndrome: Clinical Aspects." Journal of Obesity 2012 (2012): 1–13. http://dx.doi.org/10.1155/2012/473941.

Full text

Abstract:

Prader-Willi Syndrome (PWS) is a complex multisystem genetic disorder that shows great variability, with changing clinical features during a patient’s life. The syndrome is due to the loss of expression of several genes encoded on the proximal long arm of chromosome 15 (15q11.2–q13). The complex phenotype is most probably caused by a hypothalamic dysfunction that is responsible for hormonal dysfunctions and for absence of the sense of satiety. For this reason a Prader-Willi (PW) child develops hyperphagia during the initial stage of infancy that can lead to obesity and its complications. Durin

APA, Harvard, Vancouver, ISO, and other styles

28

Mikhailova, Svetlana V., and Dinara E. Ivanoshchuk. "Innate-Immunity Genes in Obesity." Journal of Personalized Medicine 11, no. 11 (2021): 1201. http://dx.doi.org/10.3390/jpm11111201.

Full text

Abstract:

The main functions of adipose tissue are thought to be storage and mobilization of the body’s energy reserves, active and passive thermoregulation, participation in the spatial organization of internal organs, protection of the body from lipotoxicity, and ectopic lipid deposition. After the discovery of adipokines, the endocrine function was added to the above list, and after the identification of crosstalk between adipocytes and immune cells, an immune function was suggested. Nonetheless, it turned out that the mechanisms underlying mutual regulatory relations of adipocytes, preadipocytes, im

APA, Harvard, Vancouver, ISO, and other styles

29

Darmawan, Arif, Sih Ageng Lumadi, and Achmad Dafir Firdaus. "LITERATURE REVIEW : FAKTOR - FAKTOR YANG BERHUBUNGAN DENGAN KEJADIAN OBESITAS PADA REMAJA LITERATURE REVIEW : FACTORS ASSOCIATED WITH OBESITY IN TEENAGER." Journal of Nursing Care and Biomoleculer 7, no. 1 (2022): 52–60. http://dx.doi.org/10.32700/jnc.v7i1.258.

Full text

Abstract:

Obesity is defined as abnormal or excessive fat accumulation that poses a risk to health. Obesity will have a negative impact on adolescent growth and development, especially in organic and psychosocial aspects. Because obesity in adolescents has a high risk of becoming obese in adulthood and has the potential to experience various causes of disease and death. This study uses a Literature Review method obtained from four data bases (Proquest, Pubmed, Google Scholar, and Garuda Portal) with the keywords Obesitas AND Remaja, Obesity AND Adolescent published in the 2015 â€“ 2020 timeframe Indones

APA, Harvard, Vancouver, ISO, and other styles

30

Muscogiuri, G., L. Barrea, F. Faggiano, et al. "Obesity in Prader–Willi syndrome: physiopathological mechanisms, nutritional and pharmacological approaches." Journal of Endocrinological Investigation 44, no. 10 (2021): 2057–70. http://dx.doi.org/10.1007/s40618-021-01574-9.

Full text

Abstract:

AbstractPrader–Willi syndrome (PWS) is a genetic disorder caused by the lack of expression of genes on the paternally inherited chromosome 15q11.2-q13 region. The three main genetic subtypes are represented by paternal 15q11-q13 deletion, maternal uniparental disomy 15, and imprinting defect. Clinical picture of PWS changes across life stages. The main clinical characteristics are represented by short stature, developmental delay, cognitive disability and behavioral diseases. Hypotonia and poor suck resulting in failure to thrive are typical of infancy. As the subjects with PWS age, clinical m

APA, Harvard, Vancouver, ISO, and other styles

31

Jańczuk, Anna, Aneta Brodziak, Tomasz Czernecki, and Jolanta Król. "Lactoferrin—The Health-Promoting Properties and Contemporary Application with Genetic Aspects." Foods 12, no. 1 (2022): 70. http://dx.doi.org/10.3390/foods12010070.

Full text

Abstract:

The aim of the study is to present a review of literature data on lactoferrin’s characteristics, applications, and multiple health-promoting properties, with special regard to nutrigenomics and nutrigenetics. The article presents a new approach to food ingredients. Nowadays, lactoferrin is used as an ingredient in food but mainly in pharmaceuticals and cosmetics. In the European Union, bovine lactoferrin has been legally approved for use as a food ingredient since 2012. However, as our research shows, it is not widely used in food production. The major producers of lactoferrin and the few avai

APA, Harvard, Vancouver, ISO, and other styles

32

Samad, Fahumiya, and Wolfram Ruf. "Inflammation, obesity, and thrombosis." Blood 122, no. 20 (2013): 3415–22. http://dx.doi.org/10.1182/blood-2013-05-427708.

Full text

Abstract:

Abstract Clinical and epidemiological studies support a connection between obesity and thrombosis, involving elevated expression of the prothrombotic molecules plasminogen activator inhibitor-1 and tissue factor (TF) and increased platelet activation. Cardiovascular diseases and metabolic syndrome–associated disorders, including obesity, insulin resistance, type 2 diabetes, and hepatic steatosis, involve inflammation elicited by infiltration and activation of immune cells, particularly macrophages, into adipose tissue. Although TF has been clearly linked to a procoagulant state in obesity, eme

APA, Harvard, Vancouver, ISO, and other styles

33

Kupczak-Wiśniowska, Bogusława, Jolanta Borgosz, Beata Podsiadło, Bogusława Serzysko, and Elżbieta Jędrkiewicz. "Obesity in children - a problem of the contemporary civilization." Pielegniarstwo XXI wieku / Nursing in the 21st Century 16, no. 1 (2017): 44–50. http://dx.doi.org/10.1515/pielxxiw-2017-0007.

Full text

Abstract:

AbstractIntroduction. In the recent thirty years obesity has become one of the most serious and still increasing health problems among children and adults in the world. Scientific magazines inform about world obesity epidemic. Lack of physical activity, excessive energy supply compared to needs of organism, as well as bad eating habits, have made obesity a civilization disease. Excess weight and obesity lead to premature atherosclerosis development and consequently, to other cardiovascular diseases such as arterial hypertension, thrombosis, cardiac insufficiency, hyperlipemia.Aim. The aim of t

APA, Harvard, Vancouver, ISO, and other styles

34

Motevalli, Mohamad, Clemens Drenowatz, Derrick R. Tanous, Naim Akhtar Khan, and Katharina Wirnitzer. "Management of Childhood Obesity—Time to Shift from Generalized to Personalized Intervention Strategies." Nutrients 13, no. 4 (2021): 1200. http://dx.doi.org/10.3390/nu13041200.

Full text

Abstract:

As a major public health concern, childhood obesity is a multifaceted and multilevel metabolic disorder influenced by genetic and behavioral aspects. While genetic risk factors contribute to and interact with the onset and development of excess body weight, available evidence indicates that several modifiable obesogenic behaviors play a crucial role in the etiology of childhood obesity. Although a variety of systematic reviews and meta-analyses have reported the effectiveness of several interventions in community-based, school-based, and home-based programs regarding childhood obesity, the pre

APA, Harvard, Vancouver, ISO, and other styles

35

Boulet, Louis-Philippe, and Qutayba Hamid. "Symposium on Obesity and Asthma –November 2, 2006." Canadian Respiratory Journal 14, no. 4 (2007): 201–8. http://dx.doi.org/10.1155/2007/342618.

Full text

Abstract:

Asthma and obesity are frequently associated, and obesity has been considered a factor contributing to both an increase in severity of asthma and to its development. The present document summarizes the proceedings of a symposium held in Montreal, Quebec, on November 2, 2006, under the auspices of the Réseau en santé respiratoire du Fonds de la recherche en santé du Québec in collaboration with the McGill University – Strauss Severe Asthma Program, Université Laval (Quebec City) and Université de Montréal. It includes an overview of the various aspects of the relationships between asthma and ob

APA, Harvard, Vancouver, ISO, and other styles

36

Yajnik, C. S. "Obesity epidemic in India: intrauterine origins?" Proceedings of the Nutrition Society 63, no. 3 (2004): 387–96. http://dx.doi.org/10.1079/pns2004365.

Full text

Abstract:

The epidemic of ‘obesity’ in India is not appreciated because BMI underestimates the adiposity of Indians. Specific adiposity measurements are necessary for recognition of the adiposity of ‘thin’ Indians. The origin of this adiposity is only beginning to be understood. In addition to a possible genetic predisposition, intrauterine ‘programming’ might be responsible, although in the ‘thrifty phenotype’ hypothesis the adiposity of the ‘thin’ fetus has not been appreciated. Dutch men who faced ‘winter hunger’ during the first trimester of their in utero life have become more obese as adults. Low

APA, Harvard, Vancouver, ISO, and other styles

37

Valenti, Maria Teresa, Angelo Pietrobelli, Maria Grazia Romanelli, et al. "Molecular and Lifestyle Factors Modulating Obesity Disease." Biomedicines 8, no. 3 (2020): 46. http://dx.doi.org/10.3390/biomedicines8030046.

Full text

Abstract:

Obesity adversely affects bone health by means of multiple mechanisms, e.g., alterations in bone-regulating hormones, inflammation, and oxidative stress. Substantial evidence supports the relationship between adiposity and bone disorders in overweight/obese individuals. It is well known that the balance between mutually exclusive differentiation of progenitor cells into osteoblasts or adipocytes is controlled by different agents, including growth factors, hormones, genetic and epigenetic factors. Furthermore, an association between vitamin D deficiency and obesity has been reported. On the oth

APA, Harvard, Vancouver, ISO, and other styles

38

Matys, Tomasz, Anna Szymańska-Chabowska, Rafał Poręba, Grzegorz Mazur, and Paweł Gać. "Genetic aspects of obesity and metabolic syndrome in people occupationally exposed to arsenic and certain heavy metals." Environmental Medicine 22, no. 1-2 (2020): 29–32. http://dx.doi.org/10.26444/ms/122202.

Full text

APA, Harvard, Vancouver, ISO, and other styles

39

Kumar, Rakesh, S. Minerva, Ruchi Shah, et al. "Role of genetic, environmental, and hormonal factors in the progression of PCOS: A review." Journal of Reproductive Healthcare and Medicine 3 (June 28, 2022): 3. http://dx.doi.org/10.25259/jrhm_16_2021.

Full text

Abstract:

Polycystic ovary syndrome (PCOS) can be mainly defined as a gynecological problem accompanied by an endocrine disturbance in females and can be seen mainly during their menstruation age. Worldwide PCOS prevalence ranges between 6% and 10%. Many of the risk factors are responsible for the pathogenesis of PCOS. Environmental factors such as environmental toxins and obesity play a major role in the occurrence of PCOS, followed by the hormonal disturbance in androgen levels, that is, hyperandrogenism, and insulin levels, that is, hyperinsulinemia. The previous studies have suggested that there is

APA, Harvard, Vancouver, ISO, and other styles

40

James, W. P. T., and A. Ralph. "New understanding in obesity research." Proceedings of the Nutrition Society 58, no. 2 (1999): 385–93. http://dx.doi.org/10.1017/s0029665199000506.

Full text

Abstract:

A public-health approach considers the relevance of nutritional research in the prevention and management of obesity. Well-defined and internationally-agreed definitions based on BMI allow an assessment of the worldwide prevalence of overweight and obesity. There are about 250 million obese adults in the world, and many more overweight. Obesity is emerging in the Third World, first in urban middle-aged women. With economic developments, obesity then occurs in men and younger women. In the West childhood obesity is rapidly emerging, with concern that early-onset obesity is especially hazardous.

APA, Harvard, Vancouver, ISO, and other styles

41

Riha, Renata L. "Genetic Aspects of the Obstructive Sleep Apnoea/Hypopnoea Syndrome – Is There a Common Link with Obesity?" Respiration 78, no. 1 (2009): 5–17. http://dx.doi.org/10.1159/000221903.

Full text

APA, Harvard, Vancouver, ISO, and other styles

42

Pinto, Renata Machado, Cristiane Cominetti, and Aparecido Divino da Cruz. "Basic and Genetic Aspects of Food Intake Control and Obesity: Role of Dopamin Receptor D2 TaqIA Polymorphism." Obesity Research - Open Journal 2, no. 4 (2016): 119–27. http://dx.doi.org/10.17140/oroj-2-119.

Full text

APA, Harvard, Vancouver, ISO, and other styles

43

Jeki, Andicha G., and Dwiko F. Rizki. "Tingkat Kegemukan dan Kebugaran Jasmani Siswa Sekolah Menengah Atas Berbasis Gender." Jurnal Ilmiah Universitas Batanghari Jambi 21, no. 1 (2021): 327. http://dx.doi.org/10.33087/jiubj.v21i1.1315.

Full text

Abstract:

Overweight and obesity are serious problems faced in the world, because it continues to increase in all countries. Riskesdas 2013 data shows that nationally, the problem of obesity in school-age children is quite high, namely adolescents at 10.8%. The main cause of obesity is a lack of physical activity which will have a direct impact on decreasing physical fitness. Physical education and sports in schools also aim to foster and develop children's potential in physical, mental, social, emotional, moral and even cognitive aspects. This study aims to see and analyze the level of obesity and phys

APA, Harvard, Vancouver, ISO, and other styles

44

Parker, Victoria E. R., and Robert K. Semple. "GENETICS IN ENDOCRINOLOGY: Genetic forms of severe insulin resistance: what endocrinologists should know." European Journal of Endocrinology 169, no. 4 (2013): R71—R80. http://dx.doi.org/10.1530/eje-13-0327.

Full text

Abstract:

‘Insulin resistance’ (IR) is a widely used clinical term. It is usually defined as a state characterised by reduced glucose-lowering activity of insulin, but it is also sometimes used as a shorthand label for a clinical syndrome encompassing major pathologies such as type 2 diabetes, polycystic ovary syndrome, fatty liver disease and atherosclerosis. Nevertheless, the precise cellular origins of IR, the causal links among these phenomena and the mechanisms underlying them remain poorly understood or contentious. Prevalent IR usually results from a genetic predisposition interacting with acquir

APA, Harvard, Vancouver, ISO, and other styles

45

Milano, Walter, Paola Ambrosio, Francesca Carizzone, et al. "Depression and Obesity: Analysis of Common Biomarkers." Diseases 8, no. 2 (2020): 23. http://dx.doi.org/10.3390/diseases8020023.

Full text

Abstract:

Depression and obesity are very common pathologies. Both cause significant problems of both morbidity and mortality and have decisive impacts not only on the health and well-being of patients, but also on socioeconomic and health expenditure aspects. Many epidemiological studies, clinical studies and meta-analyses support the association between mood disorders and obesity in relationships to different conditions such as the severity of depression, the severity of obesity, gender, socioeconomic status, genetic susceptibility, environmental influences and adverse experiences of childhood. Curren

APA, Harvard, Vancouver, ISO, and other styles

46

Kolovou, Genovefa D., Gerald F. Watts, Dimitri P. Mikhailidis, et al. "Postprandial Hypertriglyceridaemia Revisited in the Era of Non-Fasting Lipid Profile Testing: A 2019 Expert Panel Statement, Narrative Review." Current Vascular Pharmacology 17, no. 5 (2019): 515–37. http://dx.doi.org/10.2174/1570161117666190503123911.

Full text

Abstract:

Postprandial hypertriglyceridaemia, defined as an increase in plasma triglyceride-containing lipoproteins following a fat meal, is a potential risk predictor of atherosclerotic cardiovascular disease and other chronic diseases. Several non-modifiable factors (genetics, age, sex and menopausal status) and lifestyle factors (diet, physical activity, smoking status, obesity, alcohol and medication use) may influence postprandial hypertriglyceridaemia. This narrative review considers the studies published over the last decade that evaluated postprandial hypertriglyceridaemia. Additionally, the gen

APA, Harvard, Vancouver, ISO, and other styles

47

O'Malley, Maureen A., and Karola Stotz. "Intervention, integration and translation in obesity research: Genetic, developmental and metaorganismal approaches." Philosophy, Ethics, and Humanities in Medicine 6, no. 1 (2011): 2. http://dx.doi.org/10.1186/1747-5341-6-2.

Full text

APA, Harvard, Vancouver, ISO, and other styles

48

Hart, Roger J. "Physiological Aspects of Female Fertility: Role of the Environment, Modern Lifestyle, and Genetics." Physiological Reviews 96, no. 3 (2016): 873–909. http://dx.doi.org/10.1152/physrev.00023.2015.

Full text

Abstract:

Across the Western World there is an increasing trend to postpone childbearing. Consequently, the negative influence of age on oocyte quality may lead to a difficulty in conceiving for many couples. Furthermore, lifestyle factors may exacerbate a couple's difficulty in conceiving due mainly to the metabolic influence of obesity; however, the negative impacts of low peripheral body fat, excessive exercise, the increasing prevalence of sexually transmitted diseases, and smoking all have significant negative effects on fertility. Other factors that impede conception are the perceived increasing p

APA, Harvard, Vancouver, ISO, and other styles

49

Diemieszczyk, Inna, Paulina Głuszyńska, Pawel Andrzej Wojciak, Jerzy Robert Ładny, and Hady Razak Hady. "METABOLIC SYNDROME. ETIOLOGY AND PATHOGENESIS." Wiadomości Lekarskie 74, no. 10 (2021): 2510–15. http://dx.doi.org/10.36740/wlek202110126.

Full text

Abstract:

The aim of the study was to assess the impact of individual components of the metabolic syndrome on the human body, taking into account their etiology and pathogenesis. This article is analytical analysis of scientific and medical literature basing on aspects of the etiology and pathogenesis of the metabolic syndrome. The key role in the pathogenesis of the metabolic syndrome is played by insulin resistance, which may be a result of lifestyle conditions (low physical activity, overweight or obesity) or genetic background. A certain role in the pathogenesis of the metabolic syndrome is also att

APA, Harvard, Vancouver, ISO, and other styles

50

I.K., Fedyainova. "LARON SYNDROME: DIFFERENT ASPECTS OF INSULIN-LIKE GROWTH FACTOR-1 DEFICIENCY." Natural resources of the Earth and environmental protection 3, no. 1 (2022): 34–38. http://dx.doi.org/10.26787/nydha-2713-203x-2022-3-1-34-38.

Full text

Abstract:

Annotation: Laron syndrome (Laron-type dwarfism) is a rare endocrine genetic disorder with an autosomal recessive inheritance pattern caused by a variety of mutations in the growth hormone receptor. Typical manifestations include dwarfism, «doll» face and obesity. Currently, the number of patients in the world is about 350. It is noteworthy that these people almost never suffer from cancer, show a delayed age-related decline in cognitive abilities and some of them are quite resistant to type 2 diabetes. Moreover, animals with artificially induced «Laron syndrome» have a markedly increased life

APA, Harvard, Vancouver, ISO, and other styles

We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!