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Dissertations / Theses on the topic 'Object replication'

Author: Grafiati

Published: 4 June 2021

Last updated: 31 May 2022

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1

Little, Mark Cameron. "Object replication in a distributed system." Thesis, University of Newcastle Upon Tyne, 1991. http://hdl.handle.net/10443/188.

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A number of techniques have been proposed for the construction of fault—tolerant applications. One of these techniques is to replicate vital system resources so that if one copy fails sufficient copies may still remain operational to allow the application to continue to function. Interactions with replicated resources are inherently more complex than non—replicated interactions, and hence some form of replication transparency is necessary. This may be achieved by employing replica consistency protocols to mask replica failures and maintain consistency of state between functioning replicas. To

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2

Reiser, Hans P. "Flexible and reconfigurable support for fault-tolerant object replication." [S.l. : s.n.], 2007. http://nbn-resolving.de/urn:nbn:de:bsz:289-vts-58013.

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3

Soria-Rodriguez, Pedro. "Multicast-Based Interactive-Group Object-Replication For Fault Tolerance." Digital WPI, 1999. https://digitalcommons.wpi.edu/etd-theses/1069.

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"Distributed systems are clusters of computers working together on one task. The sharing of information across different architectures, and the timely and efficient use of the network resources for communication among computers are some of the problems involved in the implementation of a distributed system. In the case of a low latency system, the network utilization and the responsiveness of the communication mechanism are even more critical. This thesis introduces a new approach for the distribution of messages to computers in the system, in which, the Common Object Request Broker Architectu

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4

Chen, Chih-yung. "A framework for supporting fault-tolerant objects in distributed systems." Thesis, University of Essex, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.364551.

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5

Fan, Rui 1977. "Efficient replication of large data objects." Thesis, Massachusetts Institute of Technology, 2003. http://hdl.handle.net/1721.1/29581.

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Thesis (S.M.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, 2003.<br>Includes bibliographical references (p. 77-78).<br>Replication is an important technique for improving the reliability and scalability of data services. The primary problem encountered in replication is the trade-off between amount of replication, performance, and consistency. A rule of thumb states that any replication algorithm must sacrifice at least one of these criteria. In this thesis, we investigate replicating large data objects, such as files, whose size is large compar

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6

Баглай, Іванна Юріївна. "Онлайн-гра клієнт-серверної архітектури". Bachelor's thesis, КПІ ім. Ігоря Сікорського, 2020. https://ela.kpi.ua/handle/123456789/34948.

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Кваліфікаційна робота включає пояснювальну записку (58 с., 21 рис., 3 табл., список використаної літератури з 18 найменувань, 3 додатки). Метою бакалаврського дипломного проєкту є дослідження та структуризація теоретичних відомостей, необхідних для розробки та реалізації онлайн-гри, і на основі отриманих даних розробити власну онлайн-гру клієнт-серверної архітектури. Для досягнення поставленої мети проведено аналіз існуючих топологій з’єднання вузлів у мережі, шаблони проектів, призначених для синхронізації процесів, алгоритмів оптимізації кількості синхронізуючої інформації. В результаті р

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7

Jalan, Manisha. "Investigating the recombinational response to replication fork barriers in fission yeast." Thesis, University of Oxford, 2016. https://ora.ox.ac.uk/objects/uuid:aed1673a-f967-41a5-9643-2e432052e174.

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Timely completion of DNA replication in each cell cycle is crucial for maintaining genomic integrity. This is often challenged by the presence of various replication fork barriers (RFBs). On collision with a RFB, the fate of the replication fork remains uncertain. In some cases, the integrity of the fork is maintained until the barrier is removed or the fork is rescued by merging with the incoming fork. However, fork stalling can cause dissociation of all of the associated replication proteins (fork collapse). If this occurs, the cell's recombination machinery can intervene to help restart rep

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8

Nguyen, Michael Ong. "Investigating the molecular mechanism of replication restart in fission yeast." Thesis, University of Oxford, 2014. http://ora.ox.ac.uk/objects/uuid:b90fff59-d5b7-43b2-b648-61c0bc977ee9.

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Successful replication of the genome during each cell cycle requires that every replication fork merge with its opposing fork. However, lesions in the template DNA or protein-DNA barriers often impede replication forks and threaten the timely completion of genome duplication. If a fork encounters a replication fork barrier (RFB), it can be subject to a variety of fates. In some cases the replisome is maintained in a manner such that it can resume DNA synthesis when the barrier is removed. Alternatively the stalled fork is simply held in a competent state to merge with the opposing fork when it

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9

Nilsson, Benjamin Erik. "Viral and host factors regulating influenza virus replication." Thesis, University of Oxford, 2017. https://ora.ox.ac.uk/objects/uuid:b8953952-e6d5-4f6d-a7ba-cd55277611d1.

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Avian influenza A viruses typically do not replicate very efficiently when exposed to a mammalian host species. One of the reasons for this is the low activity of the viral RNA-dependent RNA polymerase of avian influenza viruses in mammalian cells. This host restrictive effect can be overcome by adaptive mutations in the avian polymerase, many of which are found in the 627-domain of the PB2 polymerase subunit. Deletion of the 627-domain revealed that this domain is not required for enzymatic functions of the polymerase in vitro, but that it essential for viral replication in a cellular environ

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10

Foskolou, Iosifina Petrina. "The role of hypoxia-induced RRM2B in DNA replication." Thesis, University of Oxford, 2016. https://ora.ox.ac.uk/objects/uuid:e552002e-9303-4968-babe-6092331c2540.

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Regions of low oxygen (hypoxia) occur in most solid tumours and correlate with poor patient prognosis due to their resistance to chemo- and radiotherapy and to their increased metastatic potential. Severe levels of hypoxia induce DNA replication stress characterised by an increased number of stalled replication forks and significantly reduced replication rates, which occurs in the absence of DNA damage. Ribonucleotide Reductase (RNR) is the only enzyme capable of de novo synthesis of dNTPs - the building blocks of DNA synthesis and repair. However, oxygen is essential for mammalian RNRs (RRM1/

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11

Kilwein, Mark L. "Basic objects in natural categories revisited : a replication with sighted and blind college students /." The Ohio State University, 1993. http://rave.ohiolink.edu/etdc/view?acc_num=osu1487841975357728.

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12

Hua, Hui. "Regulation of DNA replication during meiosis in fission yeast." Thesis, University of Oxford, 2012. http://ora.ox.ac.uk/objects/uuid:5d4d66ab-5441-4e96-adb1-28f4b51a975b.

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The interval between meiotic nuclear divisions can be regarded as a modified mitotic cell cycle where DNA replication is blocked. Mechanisms regulating this critical aspect of meiosis that allows haploid cells to be generated from a diploid progenitor were investigated in this project. Licensing is restricted after meiosis I due to down-regulation of Cdc18 and Cdt1. Late meiotic expression of Cdc18 and Cdt1, which load the MCM helicase onto replication origins, can lead to partial DNA replication after meiosis I. This implies that block to initiation via licensing forms an important component

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13

Maiorano, Domenico. "Role of cdc21+ and related genes in eukaryotic chromosome replication." Thesis, University of Oxford, 1995. http://ora.ox.ac.uk/objects/uuid:e4813692-f9c5-4f81-9fb8-2a13413c04bb.

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The Schizosaccharomyces pombe cdc21<sup>+</sup> gene product is related to the Mcm2-3-5 family of replication proteins. By phylogeny analysis of their protein sequences and screening for cdc21<sup>+</sup>-related sequences using molecular probes I have suggested that at least six types of cdc21<sup>+</sup>-related genes may be present in the yeast genome. The isolation of interaction suppressors of the cdc21<sup>ts</sup> mutant was attempted by overexpression of an S. pombe cDNA library. Two cDNAs were isolated, ts11<sup>+</sup> and dom1<sup>+</sup>, whose overexpression specifically affected

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Muftic, Diana. "The role of topoisomerase II in replication in mammalian cells." Thesis, University of Oxford, 2011. http://ora.ox.ac.uk/objects/uuid:8c2399d3-5cca-4c50-b1ca-8a5b96890f83.

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Topoisomerase 2α (Topo2α) is an essential protein with DNA decatenating enzymatic properties, indispensable for chromosome decatenation and segregation. It is a target for a plethora of antitumour drugs and Topo2α protein levels have been associated with the success of treatment, but also drug resistance and secondary malignancies. Although unique in its ability to resolve catenated chromosomes, the role of Topo2α in other steps of DNA metabolism, such as DNA replication elongation and termination have been elusive. A thorough understanding of the role of Topo2α in the cell will not only allow

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Horscroft, Nigel John. "Orbivirus non-structural protein NS2 : its role in virus replication." Thesis, University of Oxford, 1997. http://ora.ox.ac.uk/objects/uuid:9b550db6-dd9d-4127-941f-93eab2b6e038.

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16

Zimmer, Jutta. "Roles of BRCA1 and BRCA2 in DNA replication and genome stability." Thesis, University of Oxford, 2017. https://ora.ox.ac.uk/objects/uuid:3f595c71-7b99-4133-b215-dd5d5f19463f.

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Genomic instability is a hallmark of cancer. The tumour suppressors BRCA1 and BRCA2 play key roles in genome integrity by promoting homologous recombination DNA repair and replication fork stability. Deficiency in these functions has been described as the Achilles heel of BRCA-defective tumours. This provides an important rationale for further exploring the roles of BRCA1 and BRCA2 in DNA replication and genome stability. G-quadruplexes, alternative DNA structures formed by guanine-rich single- stranded DNA, represent natural replication fork barriers. This study demonstrates that treatment wi

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Halder, Swagata. "The role of p97 cofactors SPRTN and FAF1 in DNA replication." Thesis, University of Oxford, 2016. https://ora.ox.ac.uk/objects/uuid:8cb572fc-c426-4899-9965-f16ef48136bc.

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It is well known that cancer cells are loaded with excess proteins. To survive this proteotoxic crisis cancer cells rely heavily on the ubiquitin proteasome system (UPS). Valosin containing protein (VCP) or p97 has recently emerged as a central player of UPS. Moreover, p97 inhibitors were shown to possess potent anti-cancer properties. Owing to the essential function of p97, it can be assumed that general p97 inhibition will be equally toxic to surrounding normal tissues. Interestingly, p97 employs diverse sets of cofactors to govern distinct biological pathways. Thus understanding the p97-cof

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Beattie, Thomas R. "The molecular biology of DNA replication in the archaeon Sulfolobus solfataricus." Thesis, University of Oxford, 2012. http://ora.ox.ac.uk/objects/uuid:99d668a5-2d7a-4c7f-a1f8-b514e699347e.

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DNA replication is essential for the propagation of all living organisms. The ability of a cell to accurately duplicate its entire genome is dependent upon the activity of numerous proteins. Identifying the molecular mechanisms by which these proteins act, and determining how they are physically and functionally coordinated at sites of active DNA replication, is central to understanding this essential cellular process. Archaea possess a DNA replication machinery which is ancestral to the one present in eukaryotes, and thus these organisms serve as simplified model systems for understanding the

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LESOT, JEAN-PHILIPPE. "De l'amelioration des performances par la replication des objets : une approche par estampillage." Paris 6, 1999. http://www.theses.fr/1999PA066299.

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L'amelioration des performances d'un service distribue vis-a-vis de ses utilisateurs est un critere important de satisfaction. Or, les canaux de communication introduisent des temps de propagation et de latence qui penalisent le client. L'utilisation de portables connectes par intermittence ou avec des debits faibles et irreguliers ajoute des contraintes supplementaires. Notre travail a comme objectif principal d'ameliorer les performances des clients dans un systeme distribue a objets. Notre contribution principale est d'une part un cadre de travail (architecture partielle d'un systeme a obje

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Neo, Jacqueline Pei Shan. "The importance of DNA replication termination and the MHF complex to genome stability." Thesis, University of Oxford, 2015. http://ora.ox.ac.uk/objects/uuid:d8f726f9-e18e-43e0-b1f7-96c4f9afb064.

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The final stages of replication fork termination requires the timely and orderly orchestration of catalytic and enzymatic activities. Given the complexity of this process, it is conceivable that the final stages of fork termination is susceptible to problems that could trigger recombination, which could lead to deleterious genomic rearrangements if ectopic homologous sequences are recombined. Using the site-specific RTS1 barrier in fission yeast, I demonstrated that fork termination is generally not a recombinogenic process, and that hyper-recombination-induced by fork blockage at RTS1 is larg

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Cooper, Lisa May. "Bioprocessing of oncolytic group B adenovirus for scalable production." Thesis, University of Oxford, 2014. https://ora.ox.ac.uk/objects/uuid:bc62bd13-f43f-4d35-8975-7fc341ce209c.

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The central aim of this thesis was to develop strategies to improve the manufacture of the group B chimeric oncolytic adenovirus, ColoAd1, which rapidly kills and lyses host cells. In attempting to improve the cellular yield of ColoAd1, this thesis therefore sought to identify host infection-related factors that limited ColoAd1 production. In the widely-used manufacturing cell line, HEK293, ColoAd1 replication depleted intracellular ATP earlier than Ad11p and activated the intracellular energy sensor, AMPK. This might have reflected earlier ATP depletion, or possibly the absence of the E4orf4

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Turrell, Lauren. "The role of nucleoprotein in transcription and replication of the influenza A virus genome." Thesis, University of Oxford, 2015. https://ora.ox.ac.uk/objects/uuid:abe7310c-9b7e-4023-86a2-bae0182adb2f.

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The eight vRNA genome segments of influenza A virus are bound by the viral RNA polymerase at the 5' and 3' ends, and associated with oligomeric nucleoprotein (NP) to form viral ribonucleoprotein (vRNP) complexes. These vRNP complexes carry out both viral transcription and replication within the nucleus of the host cell. The role of NP in viral transcription and replication, although essential, is not well understood. The findings presented in this thesis support a role for NP in the elongation phase of viral transcription and replication, but suggest that NP does not play a role in the regulat

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Lee, Marvin J. R. "Targeting host cell processing glucosidase activity as a potential strategy for reducing viral replication." Thesis, University of Oxford, 2011. https://ora.ox.ac.uk/objects/uuid:f5f32e9f-fe97-44d5-8d24-5c61a109178a.

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The anti-viral efficacy of N-butyl-deoxynojirimycin (NB-DNJ, Miglustat, Zavesca) against a broad spectrum of viruses including bovine viral diarrhoea virus (BVDV), hepatitis C virus (HCV) and human immunodeficiency virus (HIV) is attributed to the disruption of viral envelope glycoprotein formation through the inhibition of the host ER alpha(α)-glucosidase activity. The DNJ-derived compound, N-(6'-4"-azido-2"-nitrophenylamino) hexyl-1-deoxynojirimycin (NAP-DNJ) is a more potent ER α-glucosidase inhibitor than NB-DNJ and together with the HCV surrogate model, BVDV, was used in this

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Abdullah, Ummi. "Biochemical studies on the role of the XPF-ERCC1 endonuclease in repairing damaged DNA replication forks." Thesis, University of Oxford, 2015. https://ora.ox.ac.uk/objects/uuid:e42b78ee-667a-4545-9ddd-27be5aea99b4.

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The human XPF (ERCC4) and ERCC1 proteins form a heterodimeric endonuclease that plays a critical role in maintaining genome stability. Mutations in the XPF gene cause several heritable disorders including Fanconi anemia (FA). This highlights the importance of DNA repair processes controlled by XPF-ERCC1, including the repair at replication forks stalled by DNA interstrand crosslinks (ICLs), for human health. Unrepaired ICLs, formed by by-products of cellular metabolism, are believed to be responsible for the genomic instability, cellular attrition and cancer predisposition seen in FA patients.

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Smith, Zoe Elizabeth. "Analysis of the 16p telomere to examine the relationship between DNA replication, chromosome structure and gene expression." Thesis, University of Oxford, 1998. https://ora.ox.ac.uk/objects/uuid:fefcbb7b-9829-4a48-8edd-9608a613922d.

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The overall aim of the laboratory is to understand how the human α globin genes are expressed in a tissue-specific and developmental-stage specific manner from their natural chromosomal environment. This gene cluster has been studied in great detail from this point of view, and it now represents an important general model to address how eukaryotic genes are regulated. Ultimately, this information may be important for the further development of strategies for effective gene transfer, particularly for patients who suffer from inherited anaemias which result from abnormal globin gene expression (

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Meyer, Robin. "Iranian-Armenian language contact in and before the 5th century CE." Thesis, University of Oxford, 2017. https://ora.ox.ac.uk/objects/uuid:38e2dcfa-4051-4e5f-a761-844526cc6449.

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This study provides new insights into the historical language contact between Classical Armenian and West Middle Iranian, specifically Parthian. Next to an up-to-date account of known lexical, morphological, and phraseological Iranian loans in Armenian, the discussion focuses on one major and three minor syntactic patterns which, it is argued, are the result of pattern replication. The major pattern, the Classical Armenian periphrastic perfect, has previously been the focus of numerous papers owing to its unusual construction: while intransitive verbs construe with nominative subjects and an o

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Ayling, Jonathan. "Epigenetic regulation of chronological and replicative longevity in Saccharomyces cerevisiae." Thesis, University of Oxford, 2012. https://ora.ox.ac.uk/objects/uuid:4f59670e-5783-4548-b553-abe1c1c0a9ab.

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Ageing and senescence remain among the most intriguing questions in biology. Saccharomyces cerevisiae has become well established as a fertile model system for the investigation of ageing. Remarkable conservation has been found to exist between interventions extending lifespan in higher animals and yeast â genetic, chemical, and nutritional â suggesting a network of common regulatory pathways controlling large-scale shifts in gene expression involved in senescence. While it has been proposed that epigenetic regulation controls these shifts, evidence remains incomplete. To address this ques

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Shepherd, Marianne E. A. "The cell cycle and DNA damage-dependent regulation of Cdt1 in schizosaccharomyces pombe." Thesis, University of Oxford, 2012. http://ora.ox.ac.uk/objects/uuid:7f2ebafb-7d0d-4c0d-b6a6-277025f71850.

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Cdt1 is a conserved and essential eukaryotic protein that is required for the licensing step of DNA replication. In order to control replication licensing and ensure a single round of DNA replication occurs per cell cycle, Cdt1 is subject to strict regulation. In Metazoa and S. pombe, Cdt1 is targeted for ubiquitylation and proteolysis in S phase and after DNA damage by the CRL4Cdt2 ubiquitin ligase. CRL4Cdt2 is activated in Metazoa by an unusual mechanism that requires an interaction between the substrate and chromatin-loaded proliferating cell nuclear antigen (PCNA). This study addressed the

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Olcina, del Molino Mónica. "Hypoxia-induced chromatin changes and ATM signalling." Thesis, University of Oxford, 2014. http://ora.ox.ac.uk/objects/uuid:dbef3c19-b7f6-42a4-a321-97d00c572ae3.

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The DNA damage response (DDR) is a complex signalling cascade triggered in response to stress, in an attempt to maintain genomic integrity. Components of this pathway, such as ATM-mediated signalling, have been proposed to act as a barrier in the early stages of tumourigenesis. Regions of low oxygen concentrations (hypoxia) occur in most solid tumours and are associated with a poor prognostic outcome. Here, we investigated the DDR induced following hypoxia-induced replication stress in an attempt to decipher the mechanism of ATM activation in response to physiological stresses that do not indu

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Marletto, Chiara. "Issues of control and causation in quantum information theory." Thesis, University of Oxford, 2013. http://ora.ox.ac.uk/objects/uuid:dba641e6-feb3-44df-968f-1b9a6564e836.

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Issues of control and causation are central to the Quantum Theory of Computation. Yet there is no place for them in fundamental laws of Physics when expressed in the prevailing conception, i.e., in terms of initial conditions and laws of motion. This thesis aims at arguing that Constructor Theory, recently proposed by David Deutsch to generalise the quantum theory of computation, is a candidate to provide a theory of control and causation within Physics. To this end, I shall present a physical theory of information that is formulated solely in constructor-theoretic terms, i.e., in terms of whi

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Tsai, Ming-Han Chloe. "The impact of HLA-driven escape mutation on viral replicative capacity and immune control in HIV infection." Thesis, University of Oxford, 2017. https://ora.ox.ac.uk/objects/uuid:398b1b9b-c8e8-49db-826d-cdbc915317a8.

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Despite the introduction of antiretroviral therapy, the HIV/HIV epidemic remains an unsolved global health problem. Amongst all the host defence mechanisms, HLA class I molecules have shown the strongest genetic association with delayed disease progression, in particular HLA-B alleles. Numerous studies have shown that the HLAmediated CD8+ T cell responses play a central role in the immune control of HIV. Yet our understanding of HLA-mediated immune control of HIV remains incomplete, even when considering the best-defined epitopes restricted by the protective HLA alleles at a population level.

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Latusek, Robert. "The role of LATS1 in DNA damage signalling." Thesis, University of Oxford, 2012. http://ora.ox.ac.uk/objects/uuid:7f21ecaf-20a6-45a9-8403-c8255955920e.

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Genomic DNA is constantly exposed to assaults, which if not dealt with, can lead to genomic instability and carcinogenesis. In response to stress including either Ionising Radiation (IR) or replication stress, ATM and ATR promote the activation of cell cycle checkpoints and initiate repair of DNA damage. Recent studies have revealed that ATM signalling can activate LATS1 via a cascade through RASSF1A and MST2. LATS1 is a tumour suppressor, which forms a barrier to carcinogenesis restricting cell proliferation and promoting apoptosis by stabilising a YAP/p73 transcriptional complex, hence upreg

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Ameling, Michael. "Systemunterstützung für den Abgleich von Geschäftsobjekten zwischen Anwendungsservern über WebServices." Doctoral thesis, Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2009. http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-24568.

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Geschäftsanwendungen wie Supply Chain Management (SCM) oder Customer Relationship Management (CRM) werden repliziert, um eine hohe Skalierbarkeit und schnellen lokalen Zugriff zu erreichen. Die Geschäftsobjekte als Datencontainer der Anwendungen müssen infolge von Änderungen synchronisiert werden. Diese Arbeit leistet einen Beitrag zur Effizienzsteigerung des Synchronisationsprozesses durch die Reduzierung der Anzahl der Synchronisationsnachrichten sowie der zu übertragenden Datenmenge - auch unter Berücksichtigung des entstehenden Mehraufwands durch zusätzliche Verarbeitungsprozesse<br>Busine

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Wright, Sam Mathew. "Structural and biophysical studies of RNA-dependent RNA polymerases." Thesis, University of Oxford, 2010. http://ora.ox.ac.uk/objects/uuid:d5c2a16d-e1e2-4c22-aca5-70f72aa96853.

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RNA-dependent RNA polymerases (RdRps) play a vital role in the life cycle of RNA viruses, being responsible for genome replication and mRNA transcription. In this thesis viral RdRps (vRdRps) of dsRNA bacteriophage phi6 (phi6 RdRp) and Severe Acute Respiratory Syndrome (SARS) coronavirus [non structural protein 12 (NSP-12)] are studied. For SARS polymerase NSP-12, a library-based screening method known as ESPRIT (Expression of Soluble Protein by Random Incremental Truncation) was employed in an attempt to isolate domains of NSP-12 that express solubly in Escherichia coli (E. coli) and are there

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Pfister, Sophia Xiao. "The three methyls : the function and therapeutic potential of histone H3K36 trimethylation." Thesis, University of Oxford, 2014. http://ora.ox.ac.uk/objects/uuid:83cfd649-b75c-49f6-b881-1c1e96cafb08.

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DNA is wrapped around proteins called histones, whose modification regulates numerous cellular processes. Therefore it is not surprising that mutations in the genes that modify the histones are frequently associated with human cancer. For example, mutations in SETD2, encoding the sole enzyme that catalyses histone H3 lysine 36 trimethylation (H3K36me3), occur frequently in multiple cancer types. This identifies H3K36me3 loss as an important event in cancer development, and also as a potential therapeutic target. This thesis investigates the following questions: (1) how does the loss of H3K36me

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Reiser, Hans Peter [Verfasser]. "Flexible and reconfigurable support for fault-tolerant object replication / vorgelegt von Hans Peter Reiser." 2006. http://d-nb.info/995639108/34.

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Cheng, Ya-Ling. "On the Design and Implementation of a Wide-Area Object-Oriented Distributed File System with Replication Management on MOSP." 2008. http://www.cetd.com.tw/ec/thesisdetail.aspx?etdun=U0001-1707200817053300.

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Cheng, Ya-Ling, and 鄭雅玲. "On the Design and Implementation of a Wide-Area Object-Oriented Distributed File System with Replication Management on MOSP." Thesis, 2008. http://ndltd.ncl.edu.tw/handle/85646602845446943654.

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碩士<br>國立臺灣大學<br>資訊管理學研究所<br>96<br>With the rapid growth of computer networks and the price-reduction of computer storage, more and more personal computer users are able to afford large hard drives and high speed internet services. Now, it is common for personal users to possess more than one storage device on different computers and backup their critical files. This is an increased demand to access, share and backup files remotely through the Internet or other networks with reasonable performance and reliability. However, most of the current distributed file systems are designed for LANs, and

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Cabrita, Gonçalo Mendes. "Non-uniform replication for replicated objects." Master's thesis, 2017. http://hdl.handle.net/10362/21766.

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A large number of web applications/services are supported by applications running in cloud computing infrastructures. Many of these application store their data in georeplicated key-value stores, that maintain replicas of the data in several data centers located across the globe. Data management in these settings is challenging, with solutions needing to balance availability and consistency. Solutions that provide high-availability, by allowing operations to execute locally in a single data center, have to cope with a weaker consistency model. In such cases, replicas may be updated concu

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