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Dissertations / Theses on the topic 'Obstructive sleep apneas'

Author: Grafiati
Published: 4 June 2025
Last updated: 1 August 2025

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1

Turino, Cecilia. "A new approach to obstructive sleep apnoea management." Doctoral thesis, Universitat de Lleida, 2021. http://hdl.handle.net/10803/673267.

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L'aplicació de la pressió positiva contínua en la via aèria superior (CPAP) representa el mètode terapèutic de referència de la Síndrome d'Apnea Obstructiva del Son (SAOS). No obstant això, la SAOS es considera una malaltia amb múltiples fenotips i resposta al tractament variable. Per tant, el tractament amb CPAP hauria d'aconsellar-se segons el fenotip dels pacients. Així doncs, es necessiten noves estratègies per millorar el compliment del mateix tractament. En el primer article hem identificat algunes variables relacionades amb la SAOS . En el segon article hem definit el perfil general d
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2

Bartolucci, Maria Lavinia <1985&gt. "Obstructive sleep apneas naturally occur in mice during REM sleep and are more prevalent in a mouse model of Down syndrome." Doctoral thesis, Alma Mater Studiorum - Università di Bologna, 2021. http://amsdottorato.unibo.it/9675/1/Tesi_finale.pdf.

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Study Objectives. The use of mouse models in sleep apnea research is limited by the belief that central (CSA) but not obstructive sleep apneas (OSA) occur in rodents. With this study we wanted to develop a protocol to look for the presence of OSAs in wild-type mice and, then, to apply it to a mouse model of Down Syndrome (DS), a human pathology characterized by a high incidence of OSAs. Methods. Nine C57Bl/6J wild-type mice were implanted with electrodes for electroencephalography (EEG), neck electromyography (nEMG), diaphragmatic activity (DIA) and then placed in a whole-body-plethysmographi
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3

Martínez, Ocaña Juan Carlos. "Hipertensión arterial resistente y síndrome de apneas-hipopneas obstructivas del sueño." Doctoral thesis, Universitat Autònoma de Barcelona, 2016. http://hdl.handle.net/10803/400224.

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El 60-83% de los pacientes con hipertensión arterial resistente (HTAR) presentan un síndrome de apneas-hipopneas obstructivas del sueño (SAHOS). OBJETIVOS: El objetivo principal del trabajo fue estudiar en pacientes con HTAR y SAHOS el efecto del tratamiento con presión positiva continua en la vía aérea (CPAP) sobre la presión arterial (PA) medida mediante monitorización ambulatoria de 24 horas (MAPA). Además se estudiaron los efectos de la CPAP sobre la rigidez arterial, la función endotelial y la expresión de diversos biomarcadores supuestamente implicados en la relación HTAR-SAHOS. PAC
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4

Vila, Martín Javier. "Tratamiento del síndrome de apneas obstructivas del sueño leve y moderado, con un modelo de férula de avance mandibular regulable: parámetros polisomnográficos y análisis de factores predictivos de éxito." Doctoral thesis, Universitat Autònoma de Barcelona, 2016. http://hdl.handle.net/10803/383051.

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INTRODUCCIÓN:El síndrome de apneas obstructivas del sueño (SAOS) es una patología de elevada prevalencia y potencial nocivo en la salud.La presión positiva continua de la vía aérea (CPAP) es el tratamiento más extendido y eficaz, pero su relativa baja adherencia disminuye su efectividad. El tratamiento alternativo a la CPAP más importanteson lasférulas de avance mandibular (FAM).Su eficacia está demostrada, aunque aproximadamente un tercio de pacientes no responden. Sería importante poder saber qué factores predisponen a su éxito o fracaso, pero faltan modelos predictivos fiables. Además hay
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5

Revol, Bruno. "Pharmacoépidémiologie des apnées du sommeil Impact of concomitant medications on obstructive sleep apnoea Drugs and obstructive sleep apnoeas Diagnosis and management of central sleep apnea syndrome Baclofen and sleep apnoea syndrome: analysis of VigiBase® the WHO pharmacovigilance database Gabapentinoids and sleep apnea syndrome: a safety signal from the WHO pharmacovigilance database Valproic acid and sleep apnea: a disproportionality signal from the WHO pharmacovigilance database Ticagrelor and Central Sleep Apnea What is the best treatment strategy for obstructive sleep apnoea-related hypertension? Who may benefit from diuretics in OSA? A propensity score-matched observational study." Thesis, Université Grenoble Alpes, 2020. http://www.theses.fr/2020GRALV026.

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Avant leur mise sur le marché, l'évaluation clinique des médicaments repose sur des essais contrôlés randomisés. Bien qu'ils représentent la méthode de référence, leurs résultats sont nécessairement limités aux patients inclus dans ces essais. De plus, ils sont d’abord conçus pour mesurer l'efficacité des traitements, avant d’évaluer leurs effets indésirables. Concernant le syndrome d'apnées du sommeil (SAS), alors que de nombreux essais médicamenteux ont été menés, la plupart des résultats sont de faible niveau de preuve, voire contradictoires. Outre la durée et les effectifs limités de ces e
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6

Lam, Chung-mei Jamie, and 林頌眉. "Obstructive sleep apnea and cardiometabolic complications." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2009. http://hub.hku.hk/bib/B43085854.

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7

Mariscal, Norma Linda, and Norma Linda Mariscal. "Management of Postoperative Obstructive Sleep Apnea." Diss., The University of Arizona, 2017. http://hdl.handle.net/10150/624558.

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Background: Obstructive sleep apnea (OSA) is a sleep disorder characterized by episodes of cessation of breathing (apnea) during sleep. Unfortunately, a significant number of surgical patients are unaware they are afflicted with this disorder increasing the risks of postoperative complications. The lingering effect of general anesthesia causes an increase in frequency of airway collapse, leading to longer periods of apnea. This increasingly common sleep disorder is concerning for many anesthesia providers. Purpose: The purpose of this study was to evaluate the anesthesia provider's knowledge
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8

Lam, Chung-mei Jamie. "Obstructive sleep apnea and cardiometabolic complications." Click to view the E-thesis via HKUTO, 2009. http://sunzi.lib.hku.hk/hkuto/record/B43085854.

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9

Wimms, Alison Jane. "Gender Differences in Obstructive Sleep Apnea." Thesis, The University of Sydney, 2019. https://hdl.handle.net/2123/21632.

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The overall aim of this thesis was to understand gender differences in obstructive sleep apnea (OSA) and use this information to develop a tailored therapy for female patients. Specific aims were to determine whether gender differences commonly reported in the literature are present in mild OSA and upper airway resistance syndrome (UARS) patient groups, and whether symptoms could be linked to respiratory parameters in these groups. The final aim was to develop, test and validate a new AutoSet treatment for female OSA patients. CHAPTER 1 of this thesis provides a detailed review of gender diffe
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10

Gunaratnam, Kogulan. "OBSTRUCTIVE SLEEP APNOEA AND PERIODONTITIS." Thesis, Faculty of Dentistry, 2008. http://hdl.handle.net/2123/4057.

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Obstructive sleep apnoea (OSA) and its associated daytime symptoms form a syndrome, obstructive sleep apnoea-hypopnoea syndrome (OSAHS) that affects about 5% of the population worldwide (Young et al 2002a, Pack 2006). OSA is characterized by repeated episodes of upper airway obstruction during sleep, resulting in recurrent hypoxemia and sleep fragmentation (Hensley & Ray 2005). These in turn are associated with neurocognitive disorders, hypertension and cardiovascular complications (Pack 2006). Current therapies for this condition include surgical interventions, oral appliances and continuous
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11

Ulander, Martin. "Psychometric aspects of obstructive sleep apnea syndrome." Doctoral thesis, Linköpings universitet, Avdelningen för neurovetenskap, 2013. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-97475.

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Introduction: Obstructive sleep apnea (OSA) is a common chronic disorder consisting of episodes with impaired breathing due to obstruction of the upper airways. Treatment with Continuous Positive Airway Pressure (CPAP) is a potentially effective treatment, but adherence is low. Several potential factors affecting adherence, e.g., subjective sleepiness and personality, are only quantifiable through questionnaires. Better knowledge about psychometric properties of such questionnaires might improve future research on CPAP adherence and thus lead to better treatment options. Aim: Study I: To descr
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12

Mason, Rebecca Helen. "Vascular complications of obstructive sleep apnoea." Thesis, University of Bristol, 2013. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.619138.

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Obstructive sleep apnoea (OSA) is the third commonest respiratory condition after Asthma and COPD and has been increasingly linked to cardiovascular consequences. This thesis examines how OSA might affect different vascular beds; large (the aorta), medium (the carotid artery) and small (retinal and cerebral blood vessels) through five different studies. Each study will be reported as a separate chapter and a final discussion will assess the overall conclusions. Methodology Study one examines the prevalence of OSA in individuals with an abdominal aortic aneurysm and demonstrates the increased p
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13

Papaioannou, Ioannis. "Glucose intolerance in obstructive sleep apnoea." Thesis, Imperial College London, 2010. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.516557.

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14

Davies, David Paul. "Snoring, obstructive sleep apnoea and stroke." Thesis, University of Newcastle Upon Tyne, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.364858.

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15

McMillan, Alison. "Obstructive sleep apnoea in older people." Thesis, Imperial College London, 2014. http://hdl.handle.net/10044/1/28969.

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Obstructive sleep apnoea (OSA) is common and the prevalence increases with age. When OSA leads to sleep disruption and excessive daytime sleepiness, it is referred to as obstructive sleep apnoea syndrome (OSAS). The aim of this thesis was to investigate the consequences of OSAS in older people (˃ 65 years) and the effect of continuous positive airway pressure (CPAP) therapy. CPAP is the treatment of choice in moderate to severe OSAS in middle aged people. However, there is a paucity of evidence on the therapeutic and economic benefits of CPAP in older people with OSAS. The two studies in this
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16

Shepherd, Kelly. "Gastro-oesophageal reflux in obstructive sleep apnoea : prevalence and mechanisms." University of Western Australia. School of Anatomy and Human Biology, 2009. http://theses.library.uwa.edu.au/adt-WU2009.0085.

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Background. Obstructive Sleep Apnoea (OSA) is associated with an increase in nocturnal gastro-oesophageal reflux (nocturnalGOR) events and symptoms, however the mechanism for this remains undefined. Treatment of OSA with continuous positive airway pressure (CPAP) has been shown to reduce nocturnalGOR in individuals with OSA however the reasons for this reduction are not clear. The combination of OSA and nocturnalGOR could be particularly problematic for individuals who have had a lung transplant in whom Bronchiolitis Obliterans Syndrome (BOS) limits survival. It is thought that GOR plays a rol
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17

Lee, Kevin Chien-Hsun. "Dentofacial morphology in children with obstructive sleep apnea." Thesis, University of British Columbia, 2015. http://hdl.handle.net/2429/54507.

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Objectives: Altered dentofacial morphology has been suggested as an etiology for childhood OSA. Nevertheless, existing reports on the dentofacial characteristics of children with OSA vary significantly and are limited by the infrequent use of polysomnography (PSG) for diagnosis. Therefore, the objective of this study is to establish the prevalence of dentofacial morphology in children with OSA diagnosed using PSG. Methods: The sample comprised 64 children between the ages of 4-16 who were referred to BC Children’s Hospital for PSG. Diagnosis of OSA was provided by an overnight, in-laboratory
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18

Kalra, Maninder. "Genetic Susceptibility to Obstructive Sleep Apnea in Children." University of Cincinnati / OhioLINK, 2008. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1226552538.

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19

Aihara, Kensaku. "Local and systemic inflammation in obstructive sleep apnea." Kyoto University, 2013. http://hdl.handle.net/2433/170073.

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20

Gagnon, Victoria Lee. "Obstructive sleep apnea syndrome and associated health risks /." Abstract Full Text (HTML) Full Text (PDF), 2008. http://eprints.ccsu.edu/archive/00000538/02/1986FT.htm.

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Thesis (M.S.) -- Central Connecticut State University, 2008.<br>Thesis advisor: Ruth Rollin. "... in partial fulfillment of the requirements for the degree of Master of Science in Biology." Includes bibliographical references (leaves 39-41). Also available via the World Wide Web.
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21

Huhtakangas, J. (Jaana). "Evolution of obstructive sleep apnea after ischemic stroke." Doctoral thesis, Oulun yliopisto, 2019. http://urn.fi/urn:isbn:9789526224343.

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Abstract In Finland, the costs of stroke are approximately 1.1 billion euros annually due to long disability and hospitalization episodes. Sleep apnea is a risk factor for stroke. The prevalence of sleep apnea among stroke patients is unknown because sleep recording is not usually performed on stroke patients. There are no previous studies investigating the association of thrombolysis on the prognosis of sleep apnea. The relation between sleep apnea and cardiovascular events is still unclear. In this prospective, observational study, I recruited voluntary, consecutive ischemic stroke patients
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22

Appelberg, Jonas. "Ventilation and Lung Volume During Sleep and in Obstructive Sleep Apnea." Doctoral thesis, Uppsala : Acta Universitatis Upsaliensis : Univ.-bibl. [distributör], 2003. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-3363.

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23

JOFFE, David. "OBSTRUCTIVE SLEEP APNOEA: THE GENESIS OF DAYTIME SOMNOLENCE AND COGNITIVE IMPAIRMENT - AROUSALS, HYPOXIA AND CIRCADIAN RHYTHM." Thesis, The University of Sydney, 1997. http://hdl.handle.net/2123/382.

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Obstructive Sleep Apnoea (OSA) is a disease characterised by repetitive upper airway obstructions which are manifest by desaturation and arousal from sleep. It has been known for many years that this interruption to the normal architecture of sleep may present to the clinician as excessive daytime somnolence often with a complaint of difficulties with concentration and short term memory. Previous work had demonstrated a relationship between variables of cognitive dysfunction in patients with obstructive sleep apnoea, however, little was known about which components of the syndrome contribute
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JOFFE, David. "OBSTRUCTIVE SLEEP APNOEA: THE GENESIS OF DAYTIME SOMNOLENCE AND COGNITIVE IMPAIRMENT - AROUSALS, HYPOXIA AND CIRCADIAN RHYTHM." University of Sydney, Respiratory Medicine, Royal North Shore Hospital, 1997. http://hdl.handle.net/2123/382.

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Obstructive Sleep Apnoea (OSA) is a disease characterised by repetitive upper airway obstructions which are manifest by desaturation and arousal from sleep. It has been known for many years that this interruption to the normal architecture of sleep may present to the clinician as excessive daytime somnolence often with a complaint of difficulties with concentration and short term memory. Previous work had demonstrated a relationship between variables of cognitive dysfunction in patients with obstructive sleep apnoea, however, little was known about which components of the syndrome contribute
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25

West, Sophie Diana. "Obstructive sleep apnoea and type 2 diabetes." Thesis, University of Leicester, 2007. http://hdl.handle.net/2381/29539.

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Aims: To establish the prevalence of OSA in individuals with type 2 diabetes, and whether treatment with CPAP improves glycaemic control and insulin resistance. Methods and Results: A questionnaire was sent to 1682 men with type 2 diabetes from hospital and primary care databases. Fifty-six percent replied; 57% scored as 'high' and 39% as 'low' risk for OSA; 4% had known OSA. Overnight oximetry in 240 respondents from the 'high' and 'low' risk groups showed 31% and 13% respectively had significant OSA, verified by sleep studies. Exploration and oximetry data to the questionnaire respondent pop
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Filtness, Ashleigh J. "Obstructive sleep apnoea and daytime driver sleepiness." Thesis, Loughborough University, 2011. https://dspace.lboro.ac.uk/2134/8338.

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Driver sleepiness is known to be a major contributor to road traffic incidents (RTIs). An initial literature review identified many studies reporting untreated obstructive sleep apnoea (OSA) sufferers as having impaired driving performance and increased RTI risk. It is consistently reported that treatment with continuous positive air pressure (CPAP) improves driving performance and decreases RTI risk, although most of these studies are conducted less than one year after starting treatment. UK law allows treated OSA patients to continue driving if their doctor states that treatment has been suc
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Coughlin, Steven Robert. "The cardiovascular consequences of obstructive sleep apnoea." Thesis, University of Liverpool, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.403099.

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Obstructive sleep apnoea (OSA) is associated with increased cardiovascular morbidity and mortality, possibly because it clusters with a number of cardiovascular risk factors that comprise and underpin the metabolic syndrome. These include, obesity, high blood pressure, insulin resistance, impaired glucose tolerance and dyslipidaemia, and an increased sympathetic activity, altered cardiac autonomic tone and reduced baroreceptor sensitivity. However, it is currently unclear whether OSA clusters with these risk factors independently of obesity as studies investigating these relationships generall
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John, Angela Beatriz. "Avaliação do sono em pacientes com mucopolissacaridose tipo VI." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2008. http://hdl.handle.net/10183/19019.

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Realizamos um estudo transversal prospectivo com o objetivo de determinar a prevalência de apnéia obstrutiva do sono em um grupo de pacientes sul-americanos com mucopolissacaridose tipo VI sem tratamento prévio ou atual com terapia de reposição enzimática ou transplante de medula óssea. Os critérios de inclusão foram: ter 4 anos ou mais de idade e confirmação bioquímica da doença (níveis reduzidos da atividade da arilsulfatase B, aumento de glicosaminoglicanos (GAGs) urinários e atividade normal de outra sulfatase). Foram avaliados 28 pacientes através de anamnese, exame físico, ecocardiograma
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Wong, Keith Keat Huat. "Measuring sleep and neurobiological functional parameters in patients with obstructive sleep apnea." University of Sydney, 2008. http://hdl.handle.net/2123/2245.

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Doctor of Philosophy (Medicine)<br>Sleepiness is an important source of morbidity in the community, with potentially catastrophic consequences of occupational or driving injuries or accidents. Although many measures of sleepiness exist, there is no gold standard. The electroencephalograph (EEG) has been studied as an indicator of sleep pressure in the waking organism, or sleep depth. A mathematical model has been developed, relating the observed EEG to interactions between groups of neurons in the cortex and thalamus (Robinson, Rennie, Rowe, O'Connor, & Gordon, 2005; Robinson, Rennie, & Wrigh
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Wong, Keith K. H. "Measuring sleep and neurobiological functional parameters in patients with obstructive sleep apnea." Connect to full text, 2007. http://hdl.handle.net/2123/2245.

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Thesis (Ph. D.)--University of Sydney, 2008.<br>Title from title screen (viewed Mar. 12, 2008). Submitted in fulfilment of the requirements for the degree of Doctor of Philosophy to the Discipline of Medicine, Faculty of Medicine. Degree awarded 2008; thesis submitted 2007. Includes bibliography. Also issued in print.
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Wong, Keith Keat Huat. "Measuring sleep and neurobiological functional parameters in patients with obstructive sleep apnea." Thesis, The University of Sydney, 2007. http://hdl.handle.net/2123/2245.

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Sleepiness is an important source of morbidity in the community, with potentially catastrophic consequences of occupational or driving injuries or accidents. Although many measures of sleepiness exist, there is no gold standard. The electroencephalograph (EEG) has been studied as an indicator of sleep pressure in the waking organism, or sleep depth. A mathematical model has been developed, relating the observed EEG to interactions between groups of neurons in the cortex and thalamus (Robinson, Rennie, Rowe, O'Connor, & Gordon, 2005; Robinson, Rennie, & Wright, 1997). These interactions are th
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Haddad, Diane. "Oxidative stress and endothelial dysfunction in obstructive sleep apnea." Connect to resource, 2010. http://hdl.handle.net/1811/45466.

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33

Brooks, Dina. "The effects of obstructive sleep apnea on blood pressure." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1996. http://www.collectionscanada.ca/obj/s4/f2/dsk3/ftp04/NQ27881.pdf.

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Iliescu, Eduard Andrei. "Prevalence of proteinuria in the obstructive sleep apnea syndrome." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2000. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape4/PQDD_0018/MQ54460.pdf.

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Champagne, Katéri A. "The association of obstructive sleep apnea and gestational hypertension /." Thesis, McGill University, 2006. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=99328.

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Rationale. Hypertension occurs in 10% of pregnancies. Snoring is a marker for sleep apnea, and is a newly identified risk factor for gestational hypertension. Moreover, sleep apnea is an independent risk factor for hypertension in the non-pregnant population. I hypothesized that sleep apnea was associated with gestational hypertension.<br>Hypothesis. The prevalence of sleep apnea is higher among pregnant women with hypertensive pregnancies than among those without hypertension during pregnancy.<br>Design. Case-control study of 17 pregnant women with gestational hypertension and 33 pregnant wom
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Hlaing, EiEi. "Neuropsychological Sequelae of Obstructive Sleep Apnea in Later Adulthood." OpenSIUC, 2015. https://opensiuc.lib.siu.edu/dissertations/1043.

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The present study examined the neuropsychological relevance of poor sleep in a sample of community dwelling healthy older adults and a clinical sample of patients with untreated obstructive sleep apnea (OSA) between 40 and 90 years of age. The cognitive performance of 67 patients with obstructive sleep apnea (OSA) was compared to those of 46 controls screened for OSA using a portable device called ApneaLinkTM. The current study identified common neuropsychological variables associated with poor sleep quality in general (i.e., as a result of daytime sleepiness) and neuropsychological variable
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Kidwai, Asif. "Technology Acceptance and Compliance in Obstructive Sleep Apnea Patients." ScholarWorks, 2018. https://scholarworks.waldenu.edu/dissertations/5209.

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The focus of this study is the problem of declining trend in obstructive sleep apnea (OSA) patient compliance. Studies reported improved compliance in patients with chronic diseases due to technology-based interventions. However, researchers have not investigated the advantages of technology to improve the compliance of OSA patients in detail. The specific problem was the lack of engagement between patients and healthcare managers, resulting in low compliance within OSA patients. The purpose of this qualitative study was to evaluate how technology-based interventions can improve OSA patient en
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Faria, Cindy. "A Síndrome da Apneia/Hipopneia Obstrutiva do Sono (SAHOS) e seu tratamento com cirurgia ortognática." Master's thesis, [s.n.], 2013. http://hdl.handle.net/10284/4146.

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Projeto de Pós-Graduação/Dissertação apresentado à Universidade Fernando Pessoa como parte dos requisitos para obtenção do grau de Mestre em Medicina Dentária<br>A Síndrome da Apneia/Hipopneia Obstrutiva do Sono (SAHOS) é uma síndrome com grande prevalência na sociedade actual, constituíndo um grande problema de saúde pública. A SAHOS ocorre pelo repetido estreitamento ou colapso das vias aéreas superiores (VAS) durante o sono provocando como principal síntoma uma hipersonolência diurna exessiva. Os factores de riscos mais comuns incluem o sexo masculino, a obesidade, um palato mole alongado e
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Matsumoto, Takeshi. "Microalbuminuria in Patients with Obstructive Sleep Apnea-Chronic Obstructive Pulmonary Disease Overlap Syndrome." Kyoto University, 2018. http://hdl.handle.net/2433/232105.

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40

Melehan, Kerri Louise. "Obstructive sleep apnoea and sexual function in men." Thesis, The University of Sydney, 2014. http://hdl.handle.net/2123/11857.

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Obstructive sleep apnoea (OSA) is associated with sexual dysfunction. Untreated OSA and erectile dysfunction (ED) have both been identified as being indicative of a high risk of developing cardiovascular disease. Treatments for ED, such as testosterone supplementation or PDE-5 inhibitors, and for OSA, such as Continuous Positive Airways Pressure (CPAP) are both readily available. The effects of these treatments on the other associated conditions have not been fully assessed. The efficacy of testosterone supplementation, in untreated OSA, on sexual function and quality of life has not been
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Seto, Boon Hong. "Maxillary Morphology In Patients With Obstructive Sleep Apnoea." Thesis, Faculty of Dentistry, 1996. http://hdl.handle.net/2123/5102.

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Craig, Sonya Elizabeth. "Cardiovascular consequences of obstructive sleep apnoea in minimally symptomatic patients." Thesis, University of Cambridge, 2015. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.708448.

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Shaikh, Zarrin F. "Patent foramen ovale in obstructive sleep apnoea and chronic obstructive pulmonary disease." Thesis, Imperial College London, 2011. http://hdl.handle.net/10044/1/9478.

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The objective of this thesis was to determine the impact of right to left shunting (RLS) through patent foramen ovale (PFO) on oxygen saturation in obstructive sleep apnoea (OSA) and chronic obstructive pulmonary disease (COPD). The first aim was to determine the prevalence of PFO in severe OSA and whether PFO closure improves nocturnal oxygen saturation. The data showed that PFO with large shunts were more prevalent, however overall prevalence was not statistically different when compared to healthy controls. PFO closure did not reduce nocturnal desaturation. The second aim was to determine w
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Tsai, Willis Harvey. "A decision rule for diagnostic testing in obstructive sleep apnea." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape8/PQDD_0021/MQ48052.pdf.

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45

Hagander, Louise. "Quantitative sensory testing, obstructive sleep apnea and peripheral nervous lesions /." Stockholm, 2006. http://diss.kib.ki.se/2006/91-7140-780-4/.

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D'ROZARIO, Angela Louise. "Electroencephalogram (EEG) biomarkers of neurobehavioural dysfunction in obstructive sleep apnea." Thesis, The University of Sydney, 2014. http://hdl.handle.net/2123/9886.

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Obstructive sleep apnea (OSA) affects an estimated 2-4% of middle–aged adults yet we are still exploring how best to delineate the neurophysiological deficits that accompany this disorder. Untreated OSA leads to an increased risk of motor vehicle accidents. Traditional polysomnographic (PSG) metrics do not consistently correlate with daytime functioning. There is a clinical need for simple biomarkers to identify individuals susceptible to OSA-related cognitive deficits. There is a close relationship between EEG-based changes in brain activity and daytime function in healthy sleepers. No studi
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47

Cayanan, Elizabeth Anne. "Obstructive Sleep Apnea and Behavioural Obesity Management in Adult Patients." Thesis, The University of Sydney, 2015. http://hdl.handle.net/2123/14765.

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The association between obstructive sleep apnea (OSA) and obesity is well established and their frequent coexistence induces cardio-metabolic impairment. While mechanical therapies such as continuous positive airway pressure (CPAP) offer symptomatic alleviation, they fail to cure OSA in the absence of treatment use. Potential disease resolution depends on obesity reduction however there is a paucity of data regarding intensive weight loss regimes such as a very low energy diet (VLED) and dietary strategies for long-term weight loss maintenance in patients suffering OSA. This thesis entails a
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48

Rowsell, Luke Joshua. "The Effect of Acute Oral Morphine on Obstructive Sleep Apnea." Thesis, The University of Sydney, 2016. http://hdl.handle.net/2123/16441.

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This thesis aims to evaluate the effect of 40mg oral slow release morphine on obstructive sleep apnea (OSA) and awake ventilatory chemoreflexes in 60 OSA men in a randomised, double-blind placebo controlled crossover study. The study attempts to phenotype and genotype the potentially large variability of OSA response to a common dose of morphine using cutting edge techniques. We found that morphine caused mild respiratory depression but did not affect the percent of TST spent below 90% oxygen saturation (T90), nor apnea-hypopnea index (AHI). However, large inter-individual variability was obse
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49

Tessema, Tizita Gedeon. "Detecting Obstructive Sleep Apnea in an Adult Primary Care Population." ScholarWorks, 2019. https://scholarworks.waldenu.edu/dissertations/6867.

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Obstructive sleep apnea (OSA) is a sleep-related disorder that pauses or decreases air flow during sleep as a result of an obstructed upper airway. About 25 million people in the United States are affected by OSA. OSA has low identification and referral rates, especially in primary care facilities as indicated by the lack of patients' sleep histories. Screening tools such as questionnaires ensure an effective detection of OSA. The practice-focused question examined whether implementing the Epworth sleepiness scale (ESS) in an outpatient primary care setting would increase the number of referra
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50

Bennett, Lesley Samantha. "Sleep fragmentation predictors of daytime sleepiness and health status in sleep apnoea." Thesis, University of Bristol, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.299534.

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