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1

Rupa, Shamima Nazneen, Bedowra Begum, Sayeeda Sultana Jolly, et al. "Effect of Combined Oral Contraceptive Pill on Serum Bilirubin and Alkaline Phosphatase." TAJ: Journal of Teachers Association 35, no. 2 (2023): 133–41. http://dx.doi.org/10.3329/taj.v35i2.63762.

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Background: Combined oral contraceptive is the most known and popular method of contraception. The combined oral contraceptive pill was the first oral contraceptive method and was commercially marketed in 1960. Earlier investigators reported that early oral contraceptive pills had many side effects. Despite the modifications on early OCPs in terms of content and dosage to lessen their side effects, newer contraceptives still have some hepatotoxic effects. Aim and Objectives: The objective of this study was to investigate the effect of low-dose OCP on S. bilirubin and ALP- one of the most impor
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Fumero, Ascensión, Rosario J. Marrero, Wenceslao Peñate, Juan M. Bethencourt, and Pedro Barreiro. "Adherence to Oral Contraception in Young Women: Beliefs, Locus of Control, and Psychological Reactance." International Journal of Environmental Research and Public Health 18, no. 21 (2021): 11308. http://dx.doi.org/10.3390/ijerph182111308.

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Background: There is a high dropout rate of oral contraceptive pills (OCP), mainly due to a lack of adherence to treatment. The aim of this study was to identify the psychological processes and attitudes toward medication involved in adherence to OCP, depending on the prescription, to avoid unintended pregnancies (AUP) or gynecological problems (GP). Methods: This cross-sectional study was conducted by asking 689 young women in the fertile period, mean age 23.41 (SD = 5.90), to complete questionnaires related to attitudes, beliefs, psychological reactance, locus of control, and adherence to co
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Shenouda, Ninette, Stacey E. Priest, Vanessa I. Rizzuto, and Maureen J. MacDonald. "Brachial artery endothelial function is stable across a menstrual and oral contraceptive pill cycle but lower in premenopausal women than in age-matched men." American Journal of Physiology-Heart and Circulatory Physiology 315, no. 2 (2018): H366—H374. http://dx.doi.org/10.1152/ajpheart.00102.2018.

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Sex hormone concentrations differ between men, premenopausal women with natural menstrual cycles (NAT), and premenopausal women using oral contraceptive pills (OCP), as well as across menstrual or OCP phases. This study sought to investigate how differences in sex hormones, particularly estradiol, between men and women and across cycle phases might influence brachial artery endothelial function. Fifty-three healthy adults (22 ± 3 yr, 20 men, 15 NAT women, and 18 second-, third-, or fourth-generation OCP women) underwent assessments of sex hormones and endothelial [flow-mediated dilation (FMD)
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Alameer, Mohammed I., Khalid Y. Muqri, Abdulaziz A. Awlaqi, et al. "Knowledge, Attitude and Practices regarding Contraceptive Pill and Its Side Effects among Women in Jazan Region, Saudi Arabia." Clinics and Practice 12, no. 3 (2022): 268–75. http://dx.doi.org/10.3390/clinpract12030032.

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Contraception is one of the common methods of family planning. The oral contraceptive pill (OCP) is among the most effective methods of contraception. This study aimed to assess the knowledge, attitude, and practice of oral contraception use and its side effects among women in the Jazan region, Saudi Arabia. A cross-sectional study was carried out among adult women 18 years and older in the Jazan region. A pre-tested questionnaire was used to assess their demographic characteristics, knowledge, attitudes, previous experience, and pattern of OCP usage. Descriptive analysis and a logistic regres
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Cree, Julia M. E., Niamh M. Brennan, Sally D. Poppitt, and Jennifer L. Miles-Chan. "The Effect of the Oral Contraceptive Pill on Acute Glycaemic Response to an Oral Glucose Bolus in Healthy Young Women: A Randomised Crossover Study." Nutrients 16, no. 20 (2024): 3490. http://dx.doi.org/10.3390/nu16203490.

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Background/Objective: The oral contraceptive pill (OCP) is widely used by women worldwide, yet the influence of the OCP on carbohydrate metabolism remains under-investigated, with existing studies being few and largely cross-sectional. The study objective was to assess, for the first time, the effect of the combined OCP on postprandial glycaemic response to an oral glucose bolus, using a randomised crossover design. Methods: The effect of a combined monophasic OCP phase on glucose homeostasis and metabolic profile was investigated in 21 healthy young women, who were regular users of either and
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Partha Sarathi Mitra, Medhatithi Barman, Pramit Goswami, Jayita Saha, and Debjit Saha. "Correlation of cervical cancers with long-term use of hormonal oral contraceptive pills - A retrospective observational multicentric study in suburban-based medical colleges in West Bengal." Asian Journal of Medical Sciences 14, no. 12 (2023): 99–105. https://doi.org/10.71152/ajms.v14i12.3387.

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Background: Hormonal oral contraceptive pills (OCP) may increase the risk of carcinoma cervix by changing the susceptibility of cervical cells to persistent infection with high-risk human papilloma virus. There is a causal and promoting association with long-term use of these pills for more than 5 years of use, and the association is diminished 10 years after last use. Aims and Objectives: In this study, retrospective data were collected to analyze the risk of association of carcinoma cervix with hormonal contraceptive pill use. Materials and Methods: Interview-based retrospective observationa
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Partha Sarathi Mitra, Medhatithi Barman, Pramit Goswami, Jayita Saha, and Debjit Saha. "Correlation of cervical cancers with long-term use of hormonal oral contraceptive pills - A retrospective observational multicentric study in suburban-based medical colleges in West Bengal." Asian Journal of Medical Sciences 14, no. 12 (2023): 99–105. http://dx.doi.org/10.3126/ajms.v14i12.58493.

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Background: Hormonal oral contraceptive pills (OCP) may increase the risk of carcinoma cervix by changing the susceptibility of cervical cells to persistent infection with high-risk human papilloma virus. There is a causal and promoting association with long-term use of these pills for more than 5 years of use, and the association is diminished 10 years after last use. Aims and Objectives: In this study, retrospective data were collected to analyze the risk of association of carcinoma cervix with hormonal contraceptive pill use. Materials and Methods: Interview-based retrospective observationa
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8

Hossain, Md Golam, Amirul Islam Talukdar, Abdullah Al-Mahmud, et al. "Oral Contraceptive Pill Use and Heart Disease Risk among Premenopausal Women." Saudi Journal of Biomedical Research 7, no. 10 (2022): 261–65. http://dx.doi.org/10.36348/sjbr.2022.v07i10.001.

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Introduction: Women's cardiovascular risk is not adequately addressed, particularly during the menopausal transition when the risk of cardiovascular events rises. Women die from cardiovascular disease (CVD) more frequently than any other cause. The study's objective was to evaluate pre-menopausal women's heart disease risk in connection to oral contraceptive tablets. Method: A comparative observational study was conducted at the department of cardiology, Prime Medical College Hospital, Rangpur, Bangladesh during the period of January 2020 to December 2020. A total of 140 participants were incl
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Priest, Stacey E., Ninette Shenouda, and Maureen J. MacDonald. "Effect of sex, menstrual cycle phase, and monophasic oral contraceptive pill use on local and central arterial stiffness in young adults." American Journal of Physiology-Heart and Circulatory Physiology 315, no. 2 (2018): H357—H365. http://dx.doi.org/10.1152/ajpheart.00039.2018.

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Arterial stiffness is associated with increased cardiovascular disease risk. Previous sex-based investigations of local and central stiffness report inconsistent findings and have not controlled for menstrual cycle phase in women. There is also evidence that sex hormones influence the vasculature, but their impact on arterial stiffness across a natural menstrual (NAT) or oral contraceptive pill (OCP) cycle has been understudied. This study sought to 1) examine potential sex differences in local and central stiffness, 2) compare stiffness profiles between NAT and OCP cycles, and 3) investigate
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Cromer, Barbara A., R. David Smith, Jennifer Dwyer, Jamie McArdle Blair, and Robert T. Brown. "A Prospective Study of Adolescents Who Choose Among Levonorgestrel Implant (Norplant), Medroxyprogesterone Acetate (Depo-Provera), or the Combined Oral Contraceptive Pill as Contraception." Pediatrics 94, no. 5 (1994): 687–94. http://dx.doi.org/10.1542/peds.94.5.687.

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Objectives. Levonorgestrel implants (Norplant) and medroxyprogesterone acetate injections (Depo-Provera) represent additional contraception options for adolescents. The purpose of this study was to examine prospectively clinical profiles among adolescents who chose one of the two long-term contraceptives compared with profiles among those who chose the combined oral contraceptive pill (OCP). Methods. Girls who needed contraception and did not require confidentiality were presented with a contraceptive menu consisting of Norplant (n = 58), Depo-Provera (n = 66), or OCP (n = 75). At baseline and
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Joseph, Jijo, Krishnapriya Pradeepkumar, and Thejalakshmi Chettyparambil Lalchand. "Myths and Misconceptions – Unraveling the Paradox of Oral Contraceptive Pills." International Journal of Health Sciences and Research 14, no. 5 (2024): 368–75. http://dx.doi.org/10.52403/ijhsr.20240549.

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Since its introduction, the oral contraceptive pill [OCP] has developed into the most utilized birth control technique, setting other birth control methods aside. These tablets have comparable benefits as well as drawbacks, with the highest level of contraceptive effectiveness and the potential for adverse effects such as venous thromboembolism [VTE]. Contraceptives have significantly improved women's health by preventing unintended pregnancies, decreasing the risk of unsafe abortions, extending the time between pregnancies, and giving women the opportunity to recuperate from the physical dema
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Ottaviano, Giancarlo, Erich Cosmi, Valentina Iacono, Bruno Scarpa, Alberto Staffieri, and Glenis K. Scadding. "Does the contraceptive pill influence peak nasal inspiratory flow values?" Rhinology journal 52, no. 4 (2014): 355–59. http://dx.doi.org/10.4193/rhino14.004.

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Background: Early oral contraceptive pills (OCP) had higher estrogen levels and have been thought to cause nasal obstruction in about 40% of women users. A recent small study conducted on women taking OCP showed no significant effects on nasal patency. The aim of the present study was to analyse in a large number of volunteers if Peak Nasal Inspiratory Flow (PNIF) values could be influenced by modern OCP. Methodology: PNIF was measured in 257 women (from 14 to 51 years old), divided into two groups: the study group composed of 109 healthy women taking modern OCP; the control group composed of
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Odutayo, Ayodele, David Cherney, Judith Miller, et al. "Transdermal contraception and the renin-angiotensin-aldosterone system in premenopausal women." American Journal of Physiology-Renal Physiology 308, no. 6 (2015): F535—F540. http://dx.doi.org/10.1152/ajprenal.00602.2014.

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The oral contraceptive pill (OCP) activates the renin-angiotensin-aldosterone system (RAAS) through first-pass hepatic metabolism. Although usually benign, RAAS activation may have detrimental effects on renal and hemodynamic function in some women. Since combined hormonal contraception with the transdermal patch (EVRA) does not undergo first-pass hepatic metabolism, we hypothesized that the RAAS response would be different from that of OCP subjects. Thirty-five nonsmoking, premenopausal women (15 control subjects, 10 OCP subjects, and 10 contraceptive patch subjects) without evidence of cardi
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Sarwat Faridi, Mehwish Rasheed, Khiaynat Sarwar Hashmi, Aashir Mehmood, Noreen Rasul, and Farhana Shabnam. "Comparison of Unintended Pregnancy Rates between OCP and Injectable Contraceptive Users; A Prospective Cohort Study in Bahawalpur." Journal of The Society of Obstetricians and Gynaecologists of Pakistan 15, no. 1 (2025): 33–36. https://doi.org/10.71104/jsogp.v15i1.878.

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Objective: To compare the rates of unintended pregnancies, adherence, and contraceptive usage patterns between oral contraceptive pill (OCP) users and injectable contraceptive users in Bahawalpur, Pakistan. Methodology: A Prospective cohort study was conducted at family planning clinics from June 2022 to May 2023 on 400 women aged 20 to 45 years using OCPs or injectable methods for at least three months. Participants were followed for one year to assess adherence, method continuation, and unintended pregnancies through regular follow-ups. SPSS version 26 was applied for data analysis. Results:
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Adawiyah, Rabiah, Inu Mulyantoro, Julian Dewantiningrum, and Noor Pramono. "Randomized Controlled Trial of Tranexamic Acid’s Effect on Bleeding Length: A Study on DMPA Users with Abnormal Uterine Bleeding Who Receive Low-Dose Oral Contraceptive Pill." Journal of Biomedicine and Translational Research 6, no. 1 (2020): 1–5. http://dx.doi.org/10.14710/jbtr.v6i1.4450.

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ABSTRACTBackground: Contraceptive injection is the most common contraception used in Indonesia. Among the contraceptive injections, depomedroxy progesterone acetate (DMPA) is the most effective method with pregnancy rate of 0,3 pregnancy in 100 women annually. Abnormal uterine bleeding (AUB) is a common side effect occurred in DMPA users which leads to the discontinuation of contraception.Objective: To explore the effect of tranexamic acid on bleeding length for DMPA users with AUB who receive low dose Oral Contraceptive Pills (OCP).Methods: We performed double blind randomized control trial b
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Khowailed, Iman Akef, Lena Volland, Ibrahim Moustafa, Cheryl Peters-Brinkerhoff, Abdulrahman M. Alsubiheen, and Haneul Lee. "Doppler Ultrasound Assessment of Blood Flow Indices in Childbearing Age Women Across the Menstrual Cycle." Medicina 61, no. 3 (2025): 389. https://doi.org/10.3390/medicina61030389.

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Background and Objectives: This study investigates the effects of hormonal fluctuations during the menstrual cycle and oral contraceptive (OCP) cycles on peripheral vascular circulation in the lower limbs of healthy childbearing-age women across different phases of the menstrual cycle. Materials and Methods: Fourteen eumenorrheic non-oral contraceptive (non-OCP) users (mean age 28.9 ± 3.5 years; height 165.0 ± 5.8 cm; weight 66.8 ± 11.2 kg) were evaluated during the follicular and ovulatory phases. Fifteen monophasic oral contraceptive (OCP) users (mean age 26.4 ± 2.67 years; height 162.3 ± 8.
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Sim, Marc, Brian Dawson, Grant Landers, et al. "Interleukin-6 and Hepcidin Levels during Hormone-Deplete and Hormone-Replete Phases of an Oral Contraceptive Cycle: A Pilot Study." Annals of Nutrition and Metabolism 70, no. 2 (2017): 100–105. http://dx.doi.org/10.1159/000465530.

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Background: In the past, elevated estradiol levels were reported to downregulate the iron regulatory hormone hepcidin, thereby potentially improving iron metabolism. As estrogen plays a role in regulating the menstrual cycle and can influence the cytokine interleukin-6 (IL-6; a hepcidin up-regulator), this investigation examined the effects of estradiol supplementation achieved by the use of a monophasic oral contraceptive pill (OCP) on IL-6, hepcidin levels and iron status during the hormone-deplete versus hormone-replete phases within an oral contraceptive cycle (OCC). Methods: Fifteen healt
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Peng, Kuan-Po, and Arne May. "Oral contraceptive use and its association with symptomatology in migraine patients." Cephalalgia Reports 2 (January 1, 2019): 251581631985600. http://dx.doi.org/10.1177/2515816319856007.

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Background: Hormonal changes in natural menstrual cycles are known to modulate and even worsen headache symptoms in migraineurs; however, the impact of oral contraceptive pills (OCP), including combined oral contraceptive (COC) and progestogen-only pills on migraine symptomatology, is little investigated. Method: In this retrospective cohort study of 1758 migraine patients, data from 1032 female patients aged 15–45 years were accessed and their contraceptive methods, if any, were analyzed. Further comparisons were conducted between patients with OCP use and those without OCP use regarding the
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Hicks, K. M., G. Onambélé-Pearson, K. Winwood, and C. I. Morse. "Oral contraceptive pill use and the susceptibility to markers of exercise-induced muscle damage." European Journal of Applied Physiology 117, no. 7 (2017): 1393–402. http://dx.doi.org/10.1007/s00421-017-3629-6.

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Abstract Purpose Firstly, to establish whether oral contraceptive pill (OCP) users are more susceptible to muscle damage compared to non-users, and secondly, to establish whether differences can be attributed to differences in patella tendon properties. Methods Nine female OCP users and 9 female non-users participated in the investigation. Combining dynamometry, electromyography and ultrasonography, patella tendon properties and vastus lateralis architectural properties were measured pre and during the first of 6 sets of 12 maximal voluntary eccentric knee extensions. Serum oestrogen levels we
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Ősz, Bianca-Eugenia, Ruxandra Ștefănescu, Amelia Tero-Vescan, et al. "Medical Knowledge, Religious Beliefs, and Free Will: Attitudes and Opinions of Various Undergraduate Female Respondents Regarding Oral Contraception. A Questionnaire-Based Study." International Journal of Environmental Research and Public Health 18, no. 7 (2021): 3502. http://dx.doi.org/10.3390/ijerph18073502.

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The decision to use oral contraception varies and is based on several considerations: Personal reasons, the evaluation of the benefit/ risk ratio, and religious beliefs. In this research, a questionnaire was distributed to 422 female students from the George Emil Palade University of Medicine, Pharmacy, Science, and Technology of Târgu Mureş, Romania (UMPhST Târgu Mureș, Romania), aged between 19 and 24 years old. The first endpoint of the study was to evaluate the use of hormonal contraception by the sexually active female population. The second endpoint was to assess the degree of awareness
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McGuinness, Ailsa, and Sarah Foley. "“Is it doing something to me?”: A qualitative study of the embodied experience of Irish women using the oral contraceptive pill." HRB Open Research 8 (July 4, 2025): 75. https://doi.org/10.12688/hrbopenres.14017.1.

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Background The oral contraceptive pill (OCP) is the most prescribed form of contraception worldwide and in Ireland. The common use of contraception in Ireland is noteworthy given the previous moral influences in Irish society. Research exploring the social and embodied experience of OCP users in this context is lacking. Methods Participants were recruited online and 11 female, Irish participants aged 23 – 29 years old took part in online, semi-structured video interviews to examine their lived experiences. Interviews were analysed using Reflexive Thematic Analysis (TA). Results Participants in
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Phillips, John, Perumal Chokkalingam, and Don McFerran. "Advice given to women who are prescribed antibiotics while taking the oral contraceptive pill." Clinical Risk 13, no. 4 (2007): 133–34. http://dx.doi.org/10.1258/135626207781251004.

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Introduction It is well established that the concurrent use of antibiotics and the oral contraceptive pill (OCP) may result in unplanned pregnancy. An audit project was conducted to ascertain the proportion of patients that were appropriately informed regarding the consequences of using antibiotics while taking the combined OCP. Patients and Methods Over two 6-month periods all female inpatients between the ages of 16 and 55 years who were discharged from the ENT ward on a course of oral antibiotics were asked if they had been made aware of the possible interaction between antibiotics and the
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Yeasmin, Tahmina, Md Shahidul Haque, Shahanara Yeasmin, and Md Ruhul Amin. "Iron status in women using oral contraceptives." Bangladesh Journal of Physiology and Pharmacology 26, no. 1-2 (2014): 25–29. http://dx.doi.org/10.3329/bjpp.v26i1-2.19963.

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Objectives: To assess the iron status of women using oral contraceptive pill (OCP) and compare this status with that of women of non-OCP users. Methods: This prospective cross-sectional comparative study was done in Dhaka Medical College from January 2006 to December 2006. Total 61 apparently healthy women of low socioeconomic class, age ranged 20-40 years were selected from different areas of Dhaka city. Of them 41 women were OCP users (Study group) and 20 women were non-OCP users (for comparison). OCP users again subdivided into subgroups according to duration of OCP use. Serum ferritin and
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Samsunnahar, Qazi Shamima Akhter, Atiquzzaman, Najneen Akhter, US Naima Begum, and Farhana Rahman. "Assessment of Coagulation Disorder in Women Taking Oral Contraceptives." Journal of Bangladesh Society of Physiologist 9, no. 1 (2015): 1–5. http://dx.doi.org/10.3329/jbsp.v9i1.22786.

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Background: Oral contraceptive pill (OCP) is related to development of hypercoagulability and the risk of thromboembolic effects in women. Objectives: To assess the coagulability status in women taking oral contraceptives by estimation of plasma fibrinogen level and total count of platelets. Methods: This cross sectional study was conducted in the Department of Physiology, Dhaka Medical College, Dhaka, during the period of January 2012 to December 2012 on sixty apparently healthy female subjects aged 25 to 45 years taking OCPs for 1 to 10 years. Thirty subjects were 1 to 5 years user group and
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Ramirez, Maria Paula Reyes, Tien-Hao Lee, Robert C. Galagan, and Dragana Lovre. "RF32 | PSUN65 Effect of Oral Contraceptive Medication on Blood Pressure, Plasma Renin, and Aldosterone Levels." Journal of the Endocrine Society 6, Supplement_1 (2022): A262. http://dx.doi.org/10.1210/jendso/bvac150.538.

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Abstract Background Combination oral contraceptive medications may cause elevations of plasma renin activity and aldosterone levels. Clinical Case A 20-year-old female with a past medical history of chronic migraines and allergic rhinitis was referred to endocrinology for evaluation of secondary hypertension after she was found to have elevated renin levels by her primary care physician. The patient was noted to be hypertensive during a tonsillectomy 4 months prior and had also experienced an increased frequency of headaches prompting an evaluation for secondary hypertension and the initiation
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Kasem, Setara Binte, TA Chowdhury, Shaikh Abdur Razzaque, Ferdousi Begum, Raisa Adiba, and Selma Anika. "Effect of Low Dose Oral Contraceptive Pill on Coagulation Status in Women with Normal and Low Body Mass Index." Journal of Bangladesh College of Physicians and Surgeons 35, no. 1 (2017): 3–8. http://dx.doi.org/10.3329/jbcps.v35i1.32564.

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Background: Oral contraceptive pill (OCP) is widely used by millions of women of various socioeconomic conditions.Use of low dose oestrogen and newer progesterone in OCP now associated with less thromboembolic and cardiovascular risk. The safety aspects of these pills had not been investigated in details in malnourished women of developing countries. In the present study the effects of the pillson coagulation status have been studied.Objective: To explore the effect of the most widely used low dose OCP (Shukhi) on coagulation status of Bangladeshi women with normal and low BMI(Body Mass Index)
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Acmaz, G., L. Cınar, B. Acmaz, et al. "The Effects of Oral Isotretinoin in Women with Acne and Polycystic Ovary Syndrome." BioMed Research International 2019 (April 7, 2019): 1–5. http://dx.doi.org/10.1155/2019/2513067.

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Introduction. Many patients who were diagnosed as polycystic ovary syndrome- (PCOS-) related acne were not capable of sustaining or beginning oral contraceptive pills (OCPs) due to pill scaring, contraindications of OCP use, migraine, or smoking. In this situation, oral isotretinoin treatment may become an important option for PCOS-related acne. The aim of the study was to determine the effects of isotretinoin treatment on PCOS patients who were complicated with severe cystic acne. Materials and Methods. This study consisted of 40 female patients diagnosed as PCOS complicated with severe cysti
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Concepcion, Kristine, Sarina Lacey, Kevin McGeechan, Jane Estoesta, Deborah Bateson, and Jessica Botfield. "Cost–benefit analysis of enhancing the uptake of long-acting reversible contraception in Australia." Australian Health Review 44, no. 3 (2020): 385. http://dx.doi.org/10.1071/ah18190.

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Objective Long-acting reversible contraception (LARC) is the most effective form of reversible contraception, but its use in Australia is low compared with other countries. The aim of this study was to evaluate the economic effect of an increase in LARC uptake to international rates. Methods An economic model was designed to assess two scenarios, namely increasing the current rate of LARC uptake of 12.5% to the international benchmark of 14.8% among: (1) women currently using the oral contraceptive pill (OCP); and (2) women at risk of pregnancy and not using contraception. Model inputs include
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Concepcion, Kristine, Sarina Lacey, Kevin McGeechan, Jane Estoesta, Deborah Bateson, and Jessica Botfield. "Corrigendum to: Cost–benefit analysis of enhancing the uptake of long-acting reversible contraception in Australia." Australian Health Review 44, no. 3 (2020): 501. http://dx.doi.org/10.1071/ah18190_co.

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ObjectiveLong-acting reversible contraception (LARC) is the most effective form of reversible contraception, but its use in Australia is low compared with other countries. The aim of this study was to evaluate the economic effect of an increase in LARC uptake to international rates.MethodsAn economic model was designed to assess two scenarios, namely increasing the current rate of LARC uptake of 12.5% to the international benchmark of 14.8% among: (1) women currently using the oral contraceptive pill (OCP); and (2) women at risk of pregnancy and not using contraception. Model inputs included c
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Chen, Ke Xun, Sandie Worley, Henry Foster, et al. "Oral contraceptive use is associated with smaller hypothalamic and pituitary gland volumes in healthy women: A structural MRI study." PLOS ONE 16, no. 4 (2021): e0249482. http://dx.doi.org/10.1371/journal.pone.0249482.

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The effects of hormonal contraceptives on structural features of the hypothalamus and pituitary are incompletely understood. One prior study reported microstructural changes in the hypothalamus with oral contraceptive pill (OCP) use. However, effects on hypothalamic volume have not been reported. One prior study reported volumetric changes in the pituitary. However, this study was limited by including participants evaluated for neurological symptoms. We sought to determine if OCP use is associated with alteration of hypothalamic or pituitary volume. High-resolution 3T MRI was performed for a p
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Chakrabartty, Sangita, Hanwang Zhang, Xiyuan Dong, and Martin Omondi Alfred. "Benefits of Oral Contraceptive Pill Pretreatment in Endometriosis for IVF/ICSI-ET: A Retrospective Cohort Study." International Current Pharmaceutical Journal 6, no. 8 (2017): 49–52. http://dx.doi.org/10.3329/icpj.v6i8.34497.

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Pretreatment with oral contraceptive pills (OCP) has been widely applied in IVF/ICSI –ET treatment. However, it remains unclear whether OCP influences pregnancy rate of fresh cycle and subsequent cumulative pregnancy rate in patients with endometriosis. In this retrospective study, a total of 512 first attempt IVF/ICSI cycles of patients with endometriosis were included and divided into two groups: the study group included 216 cycles of patients undergoing pretreatment with OCP before pituitary suppression and ovarian stimulation, while 296 cycles of patients without pretreatment were consider
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Mahendira, Dharini, Arane Thavaneswaran, Adele Carty, et al. "Analysis of the Effect of the Oral Contraceptive Pill on Clinical Outcomes in Women with Ankylosing Spondylitis." Journal of Rheumatology 41, no. 7 (2014): 1344–48. http://dx.doi.org/10.3899/jrheum.130996.

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Objective.There are unexplained sex-specific changes in the clinical expression of ankylosing spondylitis (AS). We sought to examine the potential effect of exogenous estrogen in the form of oral contraceptive pills (OCP) on AS initiation and severity.Methods.This cross-sectional study consisted of women with AS from the membership of the Spondylitis Association of America. Measures of disease severity included use of biological agents and hip replacement surgery, while Bath AS Functional Index (BASFI) scores served as a surrogate marker of disability. Information was obtained using a patient
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Samsunnahar, Farzana Akonjee Mishu, Md Abdur Razzaque Mia, Nadia Ferdous, and Sajuti Sarkar. "Study of serum zinc status in Bangladeshi women taking oral contraceptives." BIRDEM Medical Journal 10, no. 1 (2019): 12–15. http://dx.doi.org/10.3329/birdem.v10i1.44742.

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Background: Birth control pills alter women’s reproductive cycle and suppress various endocrine functions. Primary alterations of endocrine functions have secondary effects on other chemical and enzyme functions of the body. A general lowering of the body’s nutrient base occurs in women on hormonal contraception. The biochemical profile of oral contraceptive pill user women showed different changes in plasma total protein, albumin and various trace minerals like serum zinc, copper, magnesium etc. Trace minerals are necessary for endocrine function. This study was designed to evaluate serum zin
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Sultana, Abida, Shamima Rahman, and Al Mamun Mahbub Alam. "Comparison of Lipid Profiles among the Women with or without Oral Contraceptive Pill Users." Journal of Current and Advance Medical Research 3, no. 2 (2018): 43–46. http://dx.doi.org/10.3329/jcamr.v3i2.36163.

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Background: The label of Lipid profiles may vary among the oral contraceptive pill users and non-users.Objective: This present study was undertaken to compare the lipid profiles among women with or without OCP users.Methodology: This comparative cross-sectional study was conducted in the Department of Obstetrics & Gynaecology and Family Planning Department in collaboration with the Biochemistry Department at Sir Salimullah Medical College & Mitford Hospital, Dhaka from June 2009 to May 2010 for a period of one (1) year. Women using low-dose OC pill for more than one year were considere
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Zafreen, Farzana, Md Abdul Wahab, Md Abdur Razzak, and Md Habibur Rahman. "Pattern of Contraceptive Used by Tribal Couples of Chattogram Hill Tract." Journal of Armed Forces Medical College, Bangladesh 15, no. 2 (2020): 158–60. http://dx.doi.org/10.3329/jafmc.v15i2.50825.

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Introduction: Chattogram hill tract is the least economically developed area of Bangladesh where, education and health care facilities are hard to reach. Pattern of contraceptive use depends on couples’ socio-cultural, education and economic condition.
 Objective: To find out the pattern of contraceptive used by selected tribal couples of Guimara Upazila of Khagrachari District.
 Materials and Methods: This descriptive cross-sectional study was conducted from October 2016 to March 2017 on 145 married women age ranging from 15 to 45 years reported to outpatient department of Border Gu
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Arthur-Norman, Priscilla, Desmond Asamoah Bruce Otu, Frederick William Akuffo Owusu, Annabella Agyemang Aboagye, and Rahel Adutwiwah Aboagye. "Knowledge, Attitude and Usage of Female Oral Contraceptive Pills among Female Hawkers in the Central Business District, Kumasi, Ghana." International STD Research & Reviews 13, no. 1 (2024): 71–80. http://dx.doi.org/10.9734/isrr/2024/v13i1172.

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Background: The use of oral contraceptive pills (OCPs) can prevent pregnancy and improve menstrual health. Their effectiveness, ease of use, and reversibility make them a preferred choice. Accessible birth control options for all individuals, regardless of age or finances, is crucial. Understanding cultural attitudes and usage patterns of contraceptives is vital for effective reproductive health care, including emergency contraception options. Aims: This study evaluated the awareness, perceptions, and usage of oral contraceptives among women (female hawkers) in the central business district of
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El-Reshaid, Kamel, Shaikha Al-Bader, and Zaneta Markova. "Acute renal artery thrombosis associated with the use of an oral contraceptive pill." Journal of Drug Delivery and Therapeutics 10, no. 6-s (2021): 8–10. http://dx.doi.org/10.22270/jddt.v10i6-s.4494.

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Peripheral, and even visceral, venous thromboembolism is a known complication of oral contraceptive drugs (OCPs) but arterial disease, leading to renal infarction, is rarely reported. We describe a 36-year-old female patient who presented with sudden left loin pain for 2 days. Ultrasound examination showed a wedge-shaped echogenic lesion at lateral side of the left kidney. Computed tomography with contrast showed the area to be avascular and the arteriogram showed abrupt loss of the dorsal branch of left main renal artery, which lacked any deformities, confirming diagnosis of thrombosis-in-sit
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Dr., Aqsa Akram Dr. Muhammad Qasim Dr. Ayesha Hussain. "A CROSS-SECTIONAL STUDY TO EXAMINE ANTIOXIDANT STATUS OF WOMEN BY APPLYING FOUR DISSIMILAR CONTRACEPTION METHODS." INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES 05, no. 12 (2018): 13843–48. https://doi.org/10.5281/zenodo.1745494.

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<strong><em>Objective:</em></strong><em> This research is designed to examine the antioxidant status of women through the application of four dissimilar methods of contraception. </em> <strong><em>Methodology: </em></strong><em>We selected a sample of (60) non-pregnant women whose age ranged between (16 - 45) years and applied four diverse methods as, oral contraceptive pills, Norplant, injectable and intra-uterine devices (IUD) who were attending Nishter Hospital Multan. For the control group, we selected fifty-eight women, ranged from (16 &ndash; 45), seemed healthy who were not observing an
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Rahman, Md Atiqur, Md Mahfuzar Rahman, Sazia Huq, and Sardar Mahmud Hossain. "Contraceptive Practice of Married Women: Experience from a Rural Community of Bangladesh." Anwer Khan Modern Medical College Journal 5, no. 1 (2014): 14–18. http://dx.doi.org/10.3329/akmmcj.v5i1.18767.

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Bangladesh is a country having high density of population in the world. Its fertility rate ranges from 4.1 to 5.49 and life expectancy is 66years while the total fertility rate of Asia is 2.2 and life expectancy 70 years. This descriptive type of cross sectional survey was carried out among 240 married women of reproductive age from July to December, 2012 in some villages of Keranigonj, Upazila, Dhaka. 73(31%) were practicing some methods of contraception, while 167 (69%) were not using it. OCP (Oral Contraceptive Pill) was the commonest method of contraception followed by Condoms 12(5%), Inje
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Lã, Filipa M. B., and Nuria Polo. "Fundamental Frequency Variations Across the Menstrual Cycle and the Use of an Oral Contraceptive Pill." Journal of Speech, Language, and Hearing Research 63, no. 4 (2020): 1033–43. http://dx.doi.org/10.1044/2020_jslhr-19-00277.

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Purpose Concentrations of sex steroid hormones—estrogens, progesterone, and testosterone—have been associated with premenstrual and menstrual vocal symptoms. However, the extent to which these symptoms may be reflected on acoustical features of the voice is still debated. This study investigates variations in fundamental frequency ( f o ) and related parameters in connected speech across phases of the menstrual cycle and during the use of a combined oral contraceptive pill (OCP). Method Electrolaryngographic recordings were made, and blood samples were collected at three different phases of th
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Braiteh, Nabil, Raheel Chaudhry, Ibraheem Rehman, Jowana Breiteh, and Alon Yarkoni. "Acute Nonatherosclerotic Coronary Thromboembolism Presenting with an Inferior STEMI in a Patient on Oral Contraception." Case Reports in Cardiology 2021 (December 24, 2021): 1–5. http://dx.doi.org/10.1155/2021/5450376.

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Background. Direct coronary embolism in the setting of oral contraceptive pill (OCP) use is a rare adverse effect. It is known for OCP to increase the risk of thrombosis; however, leading to an inferior ST elevated myocardial infarction (STEMI) due to an acute occlusive embolism is a rare entity. Coronary embolism occurs in about 3% of patients with acute coronary syndrome. Case Report. We present a case of a young 41-year-old female with a past medical history significant for dysfunctional uterine bleeding on oral contraceptive pills, who presented to the hospital with chest pain. Her workup
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Burchall, Genia, Terrence Piva, Sanjeeva Ranasinha, and Helena Teede. "Differential Effects on Haemostatic Markers by Metformin and the Contraceptive Pill: A Randomized Comparative Trial in PCOS." Thrombosis and Haemostasis 117, no. 11 (2017): 2053–62. http://dx.doi.org/10.1160/th17-04-0248.

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Background Polycystic ovarian syndrome (PCOS) affects up to 18% of reproductive-aged women with increased risks of cardiovascular disease and venous thromboembolic disease, related to metabolic and hormonal features, obesity and an apparent hypofibrinolytic state, possibly exacerbated by current PCOS treatments. Objective To investigate and compare haemostatic impacts of common pharmacological treatments and explore relationships with hormonal and metabolic variables in PCOS. Patients/Methods This mechanistic sub-study using biobanked samples from a 6-month randomized comparative trial of phar
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Mahmood, Namra. "Activated protein C resistance in women using second generation oral contraceptives." Rawal Medical Journal 48, no. 4 (2023): 926. http://dx.doi.org/10.5455/rmj.20220902105133.

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Objective: To observe the effect of Combined oral contraceptive pills (COCPs) on activated protein C (APC) resistance after three months of its use and mean change from baseline and was stratified according to age groups and parity. Methodology: This cross-sectional prospective descriptive study was conducted in Department of Pathology, Post Graduate Medical Institute, Lahore from 1/03/2018 to 02/03/2019. It included 54 female patients aged between 18-45 years who were scheduled by the family planning clinic of Lahore General Hospital, Lahore to start second generation oral contraceptive pills
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Sultana, Abida, Kashefa Khatun, and Al Mamun Mahbub Alam. "Duration of Oral Contraceptives Use and Risk of Development of Dyslipidemia among Women in Dhaka City." Journal of Science Foundation 14, no. 2 (2017): 40–43. http://dx.doi.org/10.3329/jsf.v14i2.33443.

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AbstractBackground: Duration of oral contraceptive use is an important issue for the development of dyslipidemia among women.Objective: The purpose of the present study was to see the duration of use of OCP and the development of dyslipidemia among the women.Methodology: This case control study was carried out in the Department of Obstetrics &amp; Gynaecology and Family Planning Department in collaboration with the Biochemistry Department at Sir Salimullah Medical College &amp; Mitford Hospital, Dhaka from June 2009 to May 2010 for a period of one (1) year. Women using low-dose OC pill for mor
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Begum, Kazi Shahnaz, Shah Alam, and Tahmina Tamanna. "Changes in the Contraceptive Practice among the Women of Reproductive Age in a Selected Hospital of Dhaka City." Medicine Today 27, no. 2 (2016): 33–36. http://dx.doi.org/10.3329/medtoday.v27i2.30042.

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Family planning is an essential tool for reducing fertility rate. An increase in contraceptive prevalence rate results in reduction of population growth, which in turn contributes significantly to the improvement of people's health. This is a cross-sectional, descriptive type of study carried out among the married women attending in the gynaeout patient department of MARKS Medical College and Hospital. This study was conducted from 1st June 2013 to 31st May 2014. Sample size was 250 which were selected purposively.Reproductive history was used as research instrument for data collection. Data w
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Montoya-Botero, Pedro, Francisca Martinez, Jorge Rodríguez-Purata, Ignacio Rodríguez, Buenaventura Coroleu, and Nikolaos P. Polyzos. "The effect of type of oral contraceptive pill and duration of use on fresh and cumulative live birth rates in IVF/ICSI cycles." Human Reproduction 35, no. 4 (2020): 826–36. http://dx.doi.org/10.1093/humrep/dez299.

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Abstract STUDY QUESTION Are there any differences in the fresh (LB) and cumulative live birth rates (CLBR) of women undergoing controlled ovarian stimulation (COS) for IVF/ICSI following pretreatment with different types of oral contraceptive pills (OCP) for different durations as compared to no-OCP? SUMMARY ANSWER OCP administration for an interval of 12- to 30-day treatment period and with a 5-day washout period does not affect clinical pregnancy, LB nor cumulative LB in patients undergoing COS for an IVF cycle. WHAT IS KNOWN ALREADY The use of OCP is an effective way of treatment planning i
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Samuelson, Kathleen, Ethan M. Balk, Erika L. Sevetson, and Braden C. Fleming. "Limited Evidence Suggests a Protective Association Between Oral Contraceptive Pill Use and Anterior Cruciate Ligament Injuries in Females: A Systematic Review." Sports Health: A Multidisciplinary Approach 9, no. 6 (2017): 498–510. http://dx.doi.org/10.1177/1941738117734164.

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Context: Female athletes aged 14 to 18 years are at particular risk for anterior cruciate ligament (ACL) injuries. Hormonal factors are thought to predispose them to this injury. Oral contraceptive pills (OCPs) might reduce ACL injury risk, although the literature appears controversial. Objective: To evaluate the association between OCP use and ACL injuries in women. The secondary objective was to determine the rates of ACL injuries in the pre- and postovulatory phases of the menstrual cycle in OCP and non-OCP (NOCP) users. Data Sources: Searches were performed across 4 reference databases (Pu
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Hedin, Tosha, Poorvi Kirit Desai, and Faiza Manji. "Impact of the oral contraceptive pill on the rate of ovarian cancer incidence in different races of women." Journal of Clinical Oncology 42, no. 16_suppl (2024): 10521. http://dx.doi.org/10.1200/jco.2024.42.16_suppl.10521.

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10521 Background: The rate of ovarian cancer incidence has drastically decreased over the years, though it is the fifth most leading cause of cancer death in women. Oral contraceptive pills (OCP) are a major cause for the decline due to decreasing the number of ovulations in a woman’s lifetime. In fact, women who have ever used OCPs have a 30-50% lower risk of ovarian cancer incidence compared to women who have never used OCP. This study compares the use of OCP in different races of women and its effect on the decline in incidence of ovarian cancer. Methods: The average rate of incidence per 1
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Alhagbaker, Jawdat Mamand, Nazar Ali Shreen, Awaz Aziz Saeed, and Madiha Abbas Muhammad. "Assessment of Combined Oral Contraceptive Pill Side Effects among Women Attending Maternal Child Health Centers in Erbil." JOURNAL OF UNIVERSITY OF BABYLON for Pure and Applied Sciences 30, no. 2 (2022): 1–10. http://dx.doi.org/10.29196/jubpas.v30i2.4170.

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Purpose: Studies exploring the adverse effects of oral contraceptive pill (OCP) use among women living in Erbil/Iraq are lacking. This study aimed to assess the patterns of use and associated side effects among women in Erbil.&#x0D; Patients and methods: A face-to-face questionnaire survey inquiring about demographic information and issues related to the use of OCPs and related side effects was completed by 235 women who had used OCPs at least once in their lifetime.&#x0D; Results: The women exhibited positive attitudes towards OCP efficacy and safety, positively associated with their patterns
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Rahman, Md Atiqur, M. Rahman, M. R. Siddiqui, and J. A. Zaman. "Contraceptive Practice of Married Women: Experience from a Rural Community of Bangladesh." Journal of Medicine 15, no. 1 (2014): 09–13. http://dx.doi.org/10.3329/jom.v15i1.19852.

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Background: Bangladesh is a country having high density of population in the world. Its fertility rate ranges from 4.1 to 5.49. This study was conducted to investigate socio-demographic characteristics, type of used contraceptive method, reasons for non use of contraceptive methods and also the side effects due to use of contraceptive method among the married women in some villages of Keranigonj Upazila, Dhaka. Material and Methods: This descriptive cross sectional survey was carried out among 240 married women of reproductive age from July to December, 2012 in some villages of Keranigonj, Upa
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