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Journal articles on the topic 'Octadecadienoic acid'

Author: Grafiati

Published: 4 June 2021

Last updated: 14 February 2022

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1

Britton, Mary, Christopher Fong, David Wickens, and John Yudkin. "Diet as a source of phospholipid esterified 9,11-octadecadienoic acid in humans." Clinical Science 83, no. 1 (1992): 97–101. http://dx.doi.org/10.1042/cs0830097.

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1. Diene-conjugated fatty acids are one of the products of free-radical attack upon lipids and therefore have been used as markers of such attack. The major diene-conjugated fatty acid in human tissue and serum is an isomer of linoleic acid (9,12-octadecadienoic acid), namely 9,11-octadecadienoic acid. Diet may be another source of this isomer, raising questions as to its value as a free-radical marker. The aim of this study was to determine the importance of diet as a source of 9,11-octadecadienoic acid in phospholipid esterified fatty acids in human serum. 2. Foodstuffs rich in 9,11-octadeca

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2

Yang, Nian-Yun, Yi-Fang Yang, and Kun Li. "Analysis of Hydroxy Fatty Acids from the Pollen of Brassica campestris L. var. oleifera DC. by UPLC-MS/MS." Journal of Pharmaceutics 2013 (October 10, 2013): 1–6. http://dx.doi.org/10.1155/2013/874875.

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Ultraperformance liquid chromatography coupled with negative electrospray tandem mass spectrometry (UPLC-ESI-MS/MS) was used to determine 7 hydroxy fatty acids in the pollen of Brassica campestris L. var. oleifera DC. All the investigated hydroxy fatty acids showed strong deprotonated molecular ions [M–H]−, which underwent two major fragment pathways of the allyl scission and the β-fission of the alcoholic hydroxyl group. By comparison of their molecular ions and abundant fragment ions with those of reference compounds, they were tentatively assigned as 15,16-dihydroxy-9Z,12Z-octadecadienoic a

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3

Chen, Chien-An, Wei Lu, and Charles J. Sih. "Synthesis of 9Z,11E-octadecadienoic and 10E,12Z-octadecadienoic acids, the major components of conjugated linoleic acid." Lipids 34, no. 8 (1999): 879–84. http://dx.doi.org/10.1007/s11745-999-0436-y.

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4

Shantha, Nalur Chandrasekaran, Eric Andrew Decker, and Bernhard Hennig. "Comparison of Methylation Methods for the Quantitation of Conjugated Linoleic Acid Isomers." Journal of AOAC INTERNATIONAL 76, no. 3 (1993): 644–49. http://dx.doi.org/10.1093/jaoac/76.3.644.

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Abstract Four methylation methods were evaluated for use in the gas chromatographic (GC) quantitation of conjugated linoleic acid (CLA) isomers, which are potential anticarcinogen. The methods were (1) sodium methoxide in methanol (NaOMe-MeOH), (2) American Oil Chemists' Society (AOCS) procedure Ce 2-66, which involves methanolic sodium hydroxide followed by boron trifluoride in methanol, (3) tetramethylguanidine in methanol (TMG-MeOH), and (4) direct transesterification with methanolbenzene- acetyl chloride (DAC). Purified methyl esters of isomerized linoleic acid containing 86% CLA isomers w

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5

Ogawa, Jun, Kenji Matsumura, Shigenobu Kishino, Yoriko Omura, and Sakayu Shimizu. "Conjugated Linoleic Acid Accumulation via 10-Hydroxy-12-Octadecaenoic Acid during Microaerobic Transformation of Linoleic Acid by Lactobacillus acidophilus." Applied and Environmental Microbiology 67, no. 3 (2001): 1246–52. http://dx.doi.org/10.1128/aem.67.3.1246-1252.2001.

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ABSTRACT Specific isomers of conjugated linoleic acid (CLA), a fatty acid with potentially beneficial physiological and anticarcinogenic effects, were efficiently produced from linoleic acid by washed cells ofLactobacillus acidophilus AKU 1137 under microaerobic conditions, and the metabolic pathway of CLA production from linoleic acid is explained for the first time. The CLA isomers produced were identified as cis-9, trans-11- ortrans-9, cis-11-octadecadienoic acid andtrans-9, trans-11-octadecadienoic acid. Preceding the production of CLA, hydroxy fatty acids identified as 10-hydroxy-cis-12-o

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6

Yu, Qiong, and Shengming Ma. "An Enantioselective Synthesis of (R)-5,6-Octadecadienoic Acid." European Journal of Organic Chemistry 2015, no. 7 (2015): 1596–601. http://dx.doi.org/10.1002/ejoc.201403588.

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7

Yu, Qiong, and Shengming Ma. "An Enantioselective Synthesis of (R)-5,6-Octadecadienoic Acid." European Journal of Organic Chemistry 2017, no. 8 (2017): 1237. http://dx.doi.org/10.1002/ejoc.201700242.

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8

Spiteller, Peter, and Gerhard Spiteller. "9-Hydroxy-10,12-octadecadienoic acid (9-HODE) and 13-hydroxy-9,11-octadecadienoic acid (13-HODE): excellent markers for lipid peroxidation." Chemistry and Physics of Lipids 89, no. 2 (1997): 131–39. http://dx.doi.org/10.1016/s0009-3084(97)00070-4.

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9

Zhu, Bing Qing, Li Jing Lin, Ji Hua Li, Guo Ti Lv, and Mao Fang Huang. "Comparison of Four Different Extraction Methods of Oil from Macadamia integrifolia." Advanced Materials Research 610-613 (December 2012): 3382–86. http://dx.doi.org/10.4028/www.scientific.net/amr.610-613.3382.

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Four different extraction methods, solvent extraction, ultrasonic wave-assisted extraction, Soxhlet extraction and supercritical CO2 extraction, were used to extract oil from Macadamia integrifolia, which also named Macadamia nut oil. Fatty acid compositions of Macadamia nut oil were analyzed by gas chromatography and mass spectrometry (GC-MS). The results showed the highest extraction rate was 74.63% via Soxhlet extraction, while supercritical CO2 extraction was 70.53%, ultrasonic wave-assisted extraction was 57.19% and Solvent extraction was 50.37%. Six unsaturated fatty acids, including Z-9

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10

Psodorov, Dragan, Vera Lazic, Marijana Acanski, et al. "Fatty acid profile changes in Ricotta-filled pastry during storage investigated by a GC/MS-ANOVA." Chemical Industry and Chemical Engineering Quarterly 24, no. 2 (2018): 149–55. http://dx.doi.org/10.2298/ciceq170412027p.

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Fatty acid composition of Ricotta cheese filled bakery product was examined using a GC-MS method immediately after production and packaging in the case of a control sample, and after production, packaging under air atmosphere in a seven-layer packaging material consisting of PE/Ad/PA/Ad/PE/Ad/PET, and storing during a four weeks period at room temperature, in the case of the experimental samples. The statistical significance of the fatty acid profile change was examined using ANOVA method. The results of this research showed that there are no significant changes of fatty acids composition and

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11

Yurawecz, Martin P., Jennifer K. Hood, Magdi M. Mossoba, John A. G. Roach, and Yuoh Ku. "Furan fatty acids determined as oxidation products of conjugated octadecadienoic acid." Lipids 30, no. 7 (1995): 595–98. http://dx.doi.org/10.1007/bf02536995.

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12

Endo, Jyun-ichi, Wataru Takahashi, Mineyuki Yokoyama, and Osamu Tanaka. "Induction of gene expression for systemic acquired resistance in tobacco by 9-hydroxy-10-oxo-12(Z),15(Z)-octadecadienoic acid (KODA)." Canadian Journal of Plant Science 93, no. 5 (2013): 827–30. http://dx.doi.org/10.4141/cjps2013-060.

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Endo, J., Takahashi, W., Yokoyama, M. and Tanaka, O. 2013. Induction of gene expression for systemic acquired resistance in tobacco by 9-hydroxy-10-oxo-12( Z ),15( Z )-octadecadienoic acid (KODA). Can. Plant Sci. 93: 827–830. The reaction of 9-hydroxy-10-oxo-12(Z),15(Z)-octadecadienoic acid (KODA) with (–)-norepinephrine (NE) generates the flowering inducer FN1 of duckweed Lemna paucicostata, although KODA and NE themselves do not promote flowering. We examined the effects of FN1, KODA, and NE on the induction of gene expression for systemic acquired resistance (SAR) in tobacco (Nicotiana taba

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13

Wanga, Li, Shuguang Jian, Peng Nan, and Yang Zhong. "Chemical Composition of the Essential Oil of Elephantopus scaber from Southern China." Zeitschrift für Naturforschung C 59, no. 5-6 (2004): 327–29. http://dx.doi.org/10.1515/znc-2004-5-606.

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The essential oil of Elephantopus scaber, a famous medicinal herb from Yangjiang County in Southern China was analyzed for the first time using GC-MS. The major constituents were hexadecanoic acid (42.3%), isopropyl dimethyl tetrahydronaphthalenol (14.1%), β-sesquiphellandrene (8.3%), octadecadienoic acid (5.5%), and phytol (5.2%).

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14

St ȩ, Krystyna, Alicja Zajdel, Grażyna Świerczek, Adam Wilczok, and Tadeusz Wilczok. "Reduction of 13-Hydroperoxy-9,11-octadecadienoic Acid by Dopamine-Melanin." Biochemical and Biophysical Research Communications 244, no. 3 (1998): 781–84. http://dx.doi.org/10.1006/bbrc.1997.7678.

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15

Houston, Michelle, Matheau A. Julien, Sampath Parthasarathy, and Elliot L. Chaikof. "Oxidized linoleic acid regulates expression and shedding of syndecan-4." American Journal of Physiology-Cell Physiology 288, no. 2 (2005): C458—C466. http://dx.doi.org/10.1152/ajpcell.00001.2004.

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Syndecan-4, a heparan sulfate proteoglycan that is widely expressed in the vascular wall and as a cell surface receptor, modulates events relevant to acute tissue repair, including cell migration and proliferation, cell-substrate interactions, and matrix remodeling. While syndecan-4 expression is regulated in response to acute vascular wall injury, its regulation under chronic proatherogenic conditions such as those characterized by prolonged exposure to oxidized lipids has not been defined. In this investigation, arterial smooth muscle cells were treated with 13-hydroperoxy-9,11-octadecadieno

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16

Muellner, Markus K., Sabine M. Schreier, Hilde Laggner, et al. "Hydrogen sulfide destroys lipid hydroperoxides in oxidized LDL." Biochemical Journal 420, no. 2 (2009): 277–81. http://dx.doi.org/10.1042/bj20082421.

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LOOHs (lipid hydroperoxides) in oxLDL [oxidized LDL (low-density lipoprotein)] are potentially atherogenic compounds. Recently, H2S was identified as the third endogenous gasotransmitter in the vasculature. H2O2 is known to be destroyed by H2S. Assuming that H2S may also react with LOOHs, the results show that H2S can destroy LOOHs in oxLDL. The ability of LOOH-enriched LDL to induce HO-1 (haem oxygenase 1) in endothelial cells was abolished by H2S pretreatment. HPLC analysis showed that 9-HPODE [(9S)-hydroperoxy-(10E,12Z)-octadecadienoic acid], a compound found in oxLDL, was reduced to 9-HODE

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17

Manini, P., E. Camera, M. Picardo, A. Napolitano, and M. d’Ischia. "Free radical oxidation of coriolic acid (13-(S)-hydroxy-9Z,11E-octadecadienoic Acid)." Chemistry and Physics of Lipids 134, no. 2 (2005): 161–71. http://dx.doi.org/10.1016/j.chemphyslip.2005.01.005.

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18

Sidorov, R. A., E. I. Kuznetsova, V. P. Pchelkin, A. V. Zhukov, E. N. Gorshkova, and V. D. Tsydendambaev. "Fatty acid composition of the pollen lipids of Cycas revoluta Thunb." Grasas y Aceites 67, no. 4 (2016): 163. http://dx.doi.org/10.3989/gya.0446161.

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The fatty acid (FA) composition of total extractable and non extractable with chloroform lipids of C. revoluta pollen was determined. Among other minor FAs, unusual Δ5 polymethylene-interrupted FA, Δ5, 11-octadecadienoic acid was found. This FA was found in the seed lipids of C. revoluta earlier, but it was discovered for the first time in pollen lipids.

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19

RAYNER, Benjamin S., Roland STOCKER, Peter A. LAY, and Paul K. WITTING. "Regio- and stereo-chemical oxidation of linoleic acid by human myoglobin and hydrogen peroxide: Tyr103 affects rate and product distribution." Biochemical Journal 381, no. 2 (2004): 365–72. http://dx.doi.org/10.1042/bj20031924.

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Mb (myoglobin) plus H2O2 catalyses the oxidation of various substrates via a peroxidase-like activity. A Y103F (Tyr103→Phe) variant of human Mb has been constructed to assess the effect of exchanging an electron-rich oxidizable amino acid on the peroxidase activity of human Mb. Steady-state analyses of reaction mixtures containing Y103F Mb, purified linoleic acid and H2O2 revealed a lower total yield of lipid oxidation products than mixtures containing the wild-type protein, consistent with the reported decrease in the rate constant for reaction of Y103F Mb with H2O2 [Witting, Mauk and Lay (20

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20

Formisano, Carmen, Felice Senatore, Nelly Apostolides Arnold, Franco Piozzi, and Sergio Rosselli. "GC and GC/MS Analysis of the Essential Oil of Salvia hierosolymitana Boiss. Growing Wild in Lebanon." Natural Product Communications 2, no. 2 (2007): 1934578X0700200. http://dx.doi.org/10.1177/1934578x0700200215.

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The essential oil of the aerial parts of Salvia hierosolymitana Boiss. (Lamiaceae), growing wild in Lebanon, was obtained by hydrodistillation and analysed by GC and GC-MS. Ninety-two compounds, representing 92.7% of the oil, were identified. The major components were hexadecanoic acid (15.5%), phytol (5.4%), hexahydrofarnesyl acetone (4.6%), (Z,Z)-9,12-octadecadienoic acid (4.5%) and 4-vinylguaiacol (4.4%).

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21

Kulkarni, B., S. Chattopadhyay, A. Chattopadhyay, and V. Mamdapur. "Synthesis of the Demospongic Compounds, (6Z, 11Z)-Octadecadienoic Acid and (6Z, 11Z)-Eicosadienoic Acid." Molecules 2, no. 12 (1997): 99. http://dx.doi.org/10.3390/20600099.

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22

Kulkarni, B., S. Chattopadhyay, A. Chattopadhyay, and V. Mamdapur. "Synthesis of the Demospongic Compounds, (6Z, 11Z)-Octadecadienoic Acid and (6Z, 11Z)-Eicosadienoic Acid." Molecules 2, no. 12 (1997): 3–6. http://dx.doi.org/10.3390/jan97p2.

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23

Shibahara, Akira, Kohei Yamamoto, Kaori Shinkai, Takao Nakayama, and Goro Kajimoto. "cis-9,cis-15-Octadecadienoic acid: a novel fatty acid found in higher plants." Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism 1170, no. 3 (1993): 245–52. http://dx.doi.org/10.1016/0005-2760(93)90006-u.

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24

Natrajan, Anand, Sidney M. Hecht, Gijs A. Van der Marel, and Jacques H. Van Boom. "Activation of iron(III)-bleomycin by 10-hydroperoxy-8,12-octadecadienoic acid." Journal of the American Chemical Society 112, no. 11 (1990): 4532–38. http://dx.doi.org/10.1021/ja00167a062.

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25

Nor Omar, Muhammad, Humphrey A. Moynihan, and Richard J. Hamilton. "AsymmetricSharpless epoxidation of 13S-hydroxy- 9Z, 11E-octadecadienoic acid (13S-HODE)." European Journal of Lipid Science and Technology 105, no. 1 (2003): 43–44. http://dx.doi.org/10.1002/ejlt.200390005.

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26

Hadjiagapiou, Christos, Jeffrey Travers, Richard Fertel, and Howard Sprecher. "Metabolism of 13-hydroxy-9,11-octadecadienoic acid by MOLT-4 lymphocytes." Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism 1046, no. 2 (1990): 167–72. http://dx.doi.org/10.1016/0005-2760(90)90184-y.

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27

Adeoye-Isijola, Morenike Olutunmbi, Olufunmiso Olusola Olajuyigbe, Segun Gbolagade Jonathan, and Roger Murugas Coopoosamy. "BIOACTIVE COMPOUNDS IN ETHANOL EXTRACT OF LENTINUS SQUARROSULUS MONT - A NIGERIAN MEDICINAL MACROFUNGUS." African Journal of Traditional, Complementary and Alternative medicines 15, no. 2 (2018): 42. http://dx.doi.org/10.21010/ajtcamv15i2.6.

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Background: The continuous search for new lead compounds of therapeutic importance has become necessary in the face of treatment failures and multidrug resistance plaguing the world. While many plants and higher fungi are sources of bioactive compounds yet to be fully harnessed, understanding the bioactive components in macrofungus could serve as a lead for investigating its biological activities and medicinal potentials. Materials and Methods: The bioactive compounds in the ethanolic extract of Lentinus Squarrosulus, an edible Nigerian macrofungus, were investigated by Gas Chromatograph

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28

Toporkova, Yana Y., Elena O. Smirnova, Natalia V. Lantsova, Lucia S. Mukhtarova, and Alexander N. Grechkin. "Detection of the First Epoxyalcohol Synthase/Allene Oxide Synthase (CYP74 Clan) in the Lancelet (Branchiostoma belcheri, Chordata)." International Journal of Molecular Sciences 22, no. 9 (2021): 4737. http://dx.doi.org/10.3390/ijms22094737.

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The CYP74 clan cytochromes (P450) are key enzymes of oxidative metabolism of polyunsaturated fatty acids in plants, some Proteobacteria, brown and green algae, and Metazoa. The CYP74 enzymes, including the allene oxide synthases (AOSs), hydroperoxide lyases, divinyl ether synthases, and epoxyalcohol synthases (EASs) transform the fatty acid hydroperoxides to bioactive oxylipins. A novel CYP74 clan enzyme CYP440A18 of the Asian (Belcher’s) lancelet (Branchiostoma belcheri, Chordata) was biochemically characterized in the present work. The recombinant CYP440A18 enzyme was active towards all subs

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29

Kudumula, Neelima, Noota Divya, Nagamalla Sravika, Saketha Priya, Pachava Anusha, and Mudavath Sai Jyotsna. "MOLECULAR PROPERTIES, BIOACTIVITY SCORES, AND TOXICITY PREDICTIONS OF THE PHYTOCONSTITUENTS PRESENT IN BAUHINIA ACUMINATA." International Journal of Scientific Research and Management 9, no. 07 (2021): 408–14. http://dx.doi.org/10.18535/ijsrm/v9i07.mp02.

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ABSTRACT: To develop the herbal drug with the least side effects, there are superior opportunities to discover the medicinal and other biological properties. Natural products serve as sources of beneficial chemical molecules. For this study, Bauhinia acuminata an important medicinal plant of the Indian subcontinent that belongs to the family Fabaceae was chosen. The plant is well known for its precautionary action in tuberculosis. It has been established to possess some pharmacological activities such as membranes Stabilizing activity1, antibacterial2, anti-nociceptive3, thrombolytic act

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30

GRECHKIN, Alexander N., Lucia S. MUKHTAROVA, and Mats HAMBERG. "The lipoxygenase pathway in tulip (Tulipa gesneriana): detection of the ketol route." Biochemical Journal 352, no. 2 (2000): 501–9. http://dx.doi.org/10.1042/bj3520501.

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The in vitro metabolism of [1-14C]linoleate, [1-14C]linolenate and their 9(S)-hydroperoxides was studied in cell-free preparations from tulip (Tulipa gesneriana) bulbs, leaves and flowers. Linoleate and its 9-hydroperoxide were converted by bulb and leaf preparations into three ketols: (12Z)-9-hydroxy-10-oxo-12-octadecadienoic acid (α-ketol), (11E)-10-oxo-13-hydroxy-11-octadecadienoic acid (γ-ketol) and a novel compound, (12Z)-10-oxo-11-hydroxy-12-octadecadienoic acid (10,11-ketol), in the approximate molar proportions of 10:3:1. The corresponding 15,16-dehydro α- and γ-ketols were the main me

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31

Chou, Shen-Chieh, Tsurng-Juhn Huang, En-Hung Lin, Chun-Huei Huang, and Chang-Hung Chou. "Antihepatitis B Virus Constituents of Solanum Erianthum." Natural Product Communications 7, no. 2 (2012): 1934578X1200700. http://dx.doi.org/10.1177/1934578x1200700205.

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Eleven compounds were isolated from the methanol extract of the leaves of Solanum erianthum D. Don, including five α-linolenic acid analogs, α-linolenic acid (1), 13 S-hydroxy-9( Z),11( E)-octadecadienoic acid (2), 9S-hydroxy-10( E),12( Z), 15( Z)-octadectrienoic acid (3), 9( Z),11( E)-octadecadienoic acid (4), and octadecanoic acid (5); two benzofuran-type lactones, loliolide (6) and dihydroactinidiolide (7); two steroidal alkaloids, solasonine (8) and solamargine (9); a flavonol glycoside, camelliaside C (10); and a flavone, 5-methoxy-(3″,4″-dihydro-3″,4″-diacetoxy)-2″,2″-dimethylpyrano-(7,8

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32

Jargalsaikhan, U., S. Javzan, D. Selenge, D. Nedelcheva, S. Philipov, and J. Nadmid. "Fatty acids and their esters from Cicuta virosa L." Mongolian Journal of Chemistry 14 (October 3, 2014): 71–74. http://dx.doi.org/10.5564/mjc.v14i0.203.

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n-Hexane and chloroform fractions of aerial parts and roots of Cicuta virosa L. were investigated by GC-MS. As a result of the study 25 fatty acids and their esters have been identified. Two unsaturated esters such as linoleic acid ethyl ester (IX, 16.66%), and n- hexadecanoic acid ethyl ester (VII, 10.12%), the fatty acid n-hexadecanioc acid (VI, 8.10%) made up the bulk of the aerial parts. Four unsaturated esters such as linoleic acid ethyl ester (IX, 10.15%), dibutylphthalate (XII, 9.55%), n-hexadecanoic acid ethyl ester (VII, 8.19%) and 9, 12, 15 - octadecatrienoic acid ethyl ester (X, 5.9

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33

Holková, Ivana, Drahomíra Rauová, Michaela Mergová, Lýdia Bezáková, and Peter Mikuš. "Purification and Product Characterization of Lipoxygenase from Opium Poppy Cultures (Papaver somniferum L.)." Molecules 24, no. 23 (2019): 4268. http://dx.doi.org/10.3390/molecules24234268.

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Opium poppy (Papaver somniferum L.) is an ancient medicinal plant producing pharmaceutically important benzylisoquinoline alkaloids. In the present work we focused on the study of enzyme lipoxygenase (LOX, EC 1.13.11.12) from opium poppy cultures. LOX is involved in lipid peroxidation and lipoxygenase oxidation products of polyunsaturated fatty acids have a significant role in regulation of growth, development and plant defense responses to biotic or abiotic stress. The purpose of this study was to isolate and characterize LOX enzyme from opium poppy callus cultures. LOX was purified by ammoni

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34

Nuñez, A., T. A. Foglia, and G. J. Piazza. "Anaerobic lipoxygenase activity from Chlorella pyrenoidosa." Biochemical Society Transactions 28, no. 6 (2000): 950–53. http://dx.doi.org/10.1042/bst0280950.

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The micro-alga Chlorella pyrenoidosa expresses an enzymatic activity that cleaves the 13hydroperoxide derivatives of linoleic acid [13-hydroperoxy-9(Z),11 (E-octadecadienoic acid, 13-HPOD] and linolenic acid [13-hydroperoxy-9(Z),11(E),15(Z)-octadecatrienoic acid, 13-HPOT] into volatile C5 and non-volatile C13 oxo-products. This enzymic activity initially was attributed to a hydroperoxide lyase enzyme; however, subsequent studies showed that this cleavage activity is the result of lipoxygenase activity under anaerobic conditions. Headspace analysis of the volatile products by GC/MS showed the f

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35

Kwon, So Yeon, Karen Massey, Mark A. Watson, et al. "Oxidised metabolites of the omega-6 fatty acid linoleic acid activate dFOXO." Life Science Alliance 3, no. 2 (2020): e201900356. http://dx.doi.org/10.26508/lsa.201900356.

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Obesity-induced inflammation, or meta-inflammation, plays key roles in metabolic syndrome and is a significant risk factor in diabetes and cardiovascular disease. To investigate causal links between obesity, meta-inflammation, and insulin signaling we established a Drosophila model to determine how elevated dietary fat and changes in the levels and balance of saturated fatty acids (SFAs) and polyunsaturated fatty acids (PUFAs) influence inflammation. We observe negligible effect of saturated fatty acid on inflammation but marked enhancement or suppression by omega-6 and omega-3 PUFAs, respecti

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36

Buland, Justin R., Karla J. Wasserloos, Vladimir A. Tyurin, et al. "Biosynthesis of oxidized lipid mediators via lipoprotein-associated phospholipase A2 hydrolysis of extracellular cardiolipin induces endothelial toxicity." American Journal of Physiology-Lung Cellular and Molecular Physiology 311, no. 2 (2016): L303—L316. http://dx.doi.org/10.1152/ajplung.00038.2016.

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We (66) have previously described an NSAID-insensitive intramitochondrial biosynthetic pathway involving oxidation of the polyunsaturated mitochondrial phospholipid, cardiolipin (CL), followed by hydrolysis [by calcium-independent mitochondrial calcium-independent phospholipase A2-γ (iPLA2γ)] of oxidized CL (CLox), leading to the formation of lysoCL and oxygenated octadecadienoic metabolites. We now describe a model system utilizing oxidative lipidomics/mass spectrometry and bioassays on cultured bovine pulmonary artery endothelial cells (BPAECs) to assess the impact of CLox that we show, in v

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Corsato Alvarenga, Isabella, Charles Aldrich, and Dennis Jewell. "Influence of Liver Condition and Copper on Selective Parameters of Post-Mortem Dog Tissue Samples." Animals 8, no. 12 (2018): 237. http://dx.doi.org/10.3390/ani8120237.

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One of the liver functions is copper storage, which can be toxic when in excess. The objective of this retrospective study was to determine the relationship between hepatic copper and pathology conditions in stored samples from 55 post-mortem dogs (37 Beagles, 12 Labrador Retrievers, and 6 Labrador Mixes). The analyses evaluated data from blood chemistry and complete blood count (CBC) that were measured immediately before euthanasia, and liver biopsies which were harvested at necropsy and frozen at −80 °C. Slides for microscopic evaluation were prepared, and liver copper and plasma metabolites

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38

Adlof, R. O., and E. A. Emken. "Distribution of hexadecenoic, octadecenoic and octadecadienoic acid isomers in human tissue lipids." Lipids 21, no. 9 (1986): 543–47. http://dx.doi.org/10.1007/bf02534049.

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Kittikorn, M., K. Okawa, H. Ohara, et al. "9,10-KETOL OCTADECADIENOIC ACID (KODA) LEVELS AND FLOWER BUD FORMATION IN APPLES." Acta Horticulturae, no. 884 (December 2010): 133–37. http://dx.doi.org/10.17660/actahortic.2010.884.14.

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Chan, Cecil, Philip B. Cox, and Stanley M. Roberts. "Convergent stereocontrolled synthesis of 13-hydroxy-9Z, 11E-octadecadienoic acid (13-HODE)." Journal of the Chemical Society, Chemical Communications, no. 14 (1988): 971. http://dx.doi.org/10.1039/c39880000971.

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41

Bloch, Robert, and Marie-Thérèse Perfetti. "An efficient synthesis of 13(S)-hydroxy-9Z,11E-octadecadienoic (coriolic) acid." Tetrahedron Letters 31, no. 18 (1990): 2577–80. http://dx.doi.org/10.1016/0040-4039(90)80129-a.

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42

Jahn, Michael, and Gerhard Spiteller. "Oxidation of D-(-)-Ribose with H2O2 and Lipid Hydroperoxides." Zeitschrift für Naturforschung C 51, no. 11-12 (1996): 870–76. http://dx.doi.org/10.1515/znc-1996-11-1216.

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ᴅ-(-)-ribose was subjected to oxidation with equimolar amounts of H2O2/Fe2+ and 13-hydro-peroxy-9-cis-11-trans-octadecadienoic acid/Fe2+. Smaller carbohydrates, carbonyl compounds, hydroxy acids and polyols were produced. Identification of carbonyl compounds was achieved by trapping with pentafluorobenzylhydroxylamine hydrochloride (PFBHA-HCl). All products were identified by GC/MS after derivatization with N-methyl-N-trimethylsilyl-trifluoroacetamide (MSTFA). The reactions were repeated with ᴅ-[13C1]-ribose in order to reveal the mechanism of oxidation. A possible reaction pathway is outlined

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43

Schild, Ralf L., W. Timothy Schaiff, Matthew G. Carlson, Emily J. Cronbach, D. Michael Nelson та Yoel Sadovsky. "The Activity of PPARγ in Primary Human Trophoblasts Is Enhanced by Oxidized Lipids". Journal of Clinical Endocrinology & Metabolism 87, № 3 (2002): 1105–10. http://dx.doi.org/10.1210/jcem.87.3.8284.

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The ligand-dependent nuclear receptor PPARγ plays an important role in murine and human trophoblast differentiation. Oxidized lipids, which are implicated in the pathophysiology of placental dysfunction, have recently been identified as ligands for PPARγ. We therefore hypothesized that oxidized lipids activate PPARγ in human trophoblasts and influence placental function. To test our hypothesis, we examined the effect of 9S-hydroxy-10E,12Z-octadecadienoic acid (9-HODE), 13S-hydroxy-9Z,11E-octadecadienoic acid (13-HODE), and 15S-hydroxy-5Z,8Z,11Z,13E-eicosatetraenoic acid (15-HETE) on PPARγ acti

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44

Sutrisno, Rini Retnosari, Siti Marfu'ah, and Fauziatul Fajaroh. "Fatty Acids in Tamarindus indica L. Seeds Oil and Antibacterial Activity Assay." Key Engineering Materials 811 (July 2019): 40–46. http://dx.doi.org/10.4028/www.scientific.net/kem.811.40.

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The research was conducted to investigate the oil and fatty acids contained in Tamarindus indica Linn (tamarind) seeds oil. Tamarind seeds oil was isolated by extraction and fractionation. The fatty acids content in oil were identified as fatty acid methyl ester. Fatty acid methyl ester was produced from trans-esterification reaction of tamarind seed oil with methanol and boron trifluoride catalyst (MeOH/BF3). Identification of fatty acid methyl ester was carried out by gas chromatograph mass spectrometry (GC-MS). The fatty acids in the Tamarindus indica seed oil are saturated and unsaturated

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Wei, Xin Jun, Yong Sheng Zhang, and Ben Guo Liu. "Characterization of the Flavor Compounds in Paprika Sausage by Gas Chromatography Mass Spectrometry." Advanced Materials Research 554-556 (July 2012): 1585–88. http://dx.doi.org/10.4028/www.scientific.net/amr.554-556.1585.

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The flavor compounds in paprika sausage were investigated by using gas chromatography mass spectrometry (GC-MS) in this study. By comparing with NIST mass spectral database, 11 flavor compounds including caryophyllene, 9, 12-Octadecadienoic acid, 4-Heptyn-2-ol, were identified. The obtained results could be used to establish the method analyzing the flavor ingredients in low temperature-heated meat product.

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Weber, Daniela, Gilda Erosa, Olov Sterner, and Timm Anke. "New Bioactive Sesquiterpenes from Ripartites metrodii and R. tricholoma." Zeitschrift für Naturforschung C 61, no. 9-10 (2006): 663–69. http://dx.doi.org/10.1515/znc-2006-9-1009.

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AbstractThe metabolites of two different Ripartites species, R. tricholoma (A. & S. ex Fr.) Karst. and R. metrodii Huijsm. were investigated. Three new sesquiterpenes were isolated from three different strains. In addition, the strains produced 13-oxo-9(Z),11(E)-octadecadienoic acid, psathyrellon A, 5-desoxyilludosin, an illudane (previously isolated from a Bovista sp.) 96042 and demethylovalicin, five known compounds.

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Reddy, P. Srinivas, T. Charles Kumar, M. Narsa Reddy, C. Sarada, and P. Reddanna. "Differential formation of octadecadienoic acid and octadecatrienoic acid products in control and injured/infected potato tubers." Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids 1483, no. 2 (2000): 294–300. http://dx.doi.org/10.1016/s1388-1981(99)00191-2.

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Yohko, Fujimoto, Sumiya Toshiki, Tsunomori Masahide, Nlshida Hlroko, Sakuma Satoru, and Fujita Tadashi. "Effect of 13-hydroperoxy-9,11-octadecadienoic acid (13-hpode) on arachidonic acid metabolism in rabbit platelets." International Journal of Biochemistry 26, no. 1 (1994): 127–31. http://dx.doi.org/10.1016/0020-711x(94)90205-4.

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Wang, Bao Qin, Ze Ping Xu, and Chuan Lun Yang. "The Chemical Compositions of the Lipid Extracted from Fermented Mycelium of Grifola frondosa." Advanced Materials Research 503-504 (April 2012): 412–15. http://dx.doi.org/10.4028/www.scientific.net/amr.503-504.412.

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The lipids from fermented mycelium of G. frondosa were extracted using supercritical flow CO2 and analyzed by GC-MS. There were 24 compounds detected in the lipids and the main compositions were octadecadienoic acid, eicosadienoic acid and hexadecanoic acid, with a little terpenoid compounds of cedrene, caryophyllene, isopropenylcarene, squalene, and some ergosterol. The total fatty acid content of the lipid was 89.18%, in which, the unsaturated fatty acid was 71.09%. The main compositions of saturated fatty acid were hexadecanoic acid and the main compositions of unsaturated fatty acid were l

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Razmaitė, V., R. Šveistienė, and G. J. Švirmickas. "Compositional characteristics and nutritional quality of Eurasian beaver (Castor fiber) meat." Czech Journal of Food Sciences 29, No. 5 (2011): 480–86. http://dx.doi.org/10.17221/313/2010-cjfs.

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The meat of Eurasian beaver (Castor fiber) as obtained in Lithuania contained 21.4% crude protein with high amounts of glutamic acid (152.6 mg/g), aspartic acid (87.6 mg/g), lysine (81.8 mg/g), leucine (75.7 mg/g), arginine (60.4 mg/g), and isoleucine (60.1 mg/g). This meat could be a high quality protein source because of its well-balanced essential amino acid composition. Polyunsaturated fatty acids were predominant with a percentage of 41.58% in thighs and of 42.12% in the fat depot of tails. Hexadecanoic acid (C16:0) was the dominant fatty acid in thigh muscles, followed by octadecadienoic

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