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Dissertations / Theses on the topic 'ODBC'
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Cozin, Kátia Mitiko Firmino Suzuki. "Sistema Reastreador de Operações ODBC em Ambientes Intranet." Universidade de São Paulo, 1999. http://www.teses.usp.br/teses/disponiveis/55/55134/tde-06032018-114505/.
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Os avatars, ou ferramentas de análise de desempenho de sistemas distribuídos baseadas em tecnologias de realidade virtual, surgem como novas ferramentas de monitoramento e visualização gráfica do comportamento dos sistemas paralelos e distribuídos. Neles o formato de arquivo utilizado é o SDDF (Self-Defining Data Format) que vem se tornando padrão de armazenamento entre as ferramentas baseadas nesta tecnologia. A finalidade desde trabalho é investigar e desenvolver um sistema de captura e rastreamento das operações no formato ODBC (Open Database Connectivity), que ocorrem no ambiente intranet e disponibilizar tais dados no formato especifico, o SDDF possibilitando a visualização em avatars.The avatars or analyzer of performance toolkits appear as new tools to monitoring and graphics visualization for parallel and distributed systems. They are based on virtual reality technologies. Where, their file formats are SDDF (Self-Defining Data Format), which are becoming a storage standard among these technology-based tools. In this work have been investigated and developed a system that provides the capture and the rastering of aze ODBC (Open Database Connectivity), and these operations occur on intranet environment. The system aini is to disponibilize the collected of information in the SDDF specified formar, becoming able their visualiza tion on avatars.
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Challa, Varshi. "Accessing timesheets via internet through ASP and ODBC." CSUSB ScholarWorks, 2000. https://scholarworks.lib.csusb.edu/etd-project/1605.
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The purpose of this project is to develop a computerized timesheet application. Using this application, an employee of a company can log onto the company's Web site and fill out a timesheet from anywhere in the world. The project involved automating timesheet data entry and approval procedures using contemporary technologies like Active Server Pages (ASP), JavaScript, VB Script, Component Object Model (COM), Components and Open Database connectivity (ODBC).
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He, Weihua. "A Java-based architecture design tool based on ODBC access to a geometric database." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1998. http://www.collectionscanada.ca/obj/s4/f2/dsk2/ftp03/MQ39661.pdf.
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Hadiani, Saman. "Design och implementation av konfigurationsverktyg för funktionsblock." Thesis, Linköping University, Department of Computer and Information Science, 2004. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-2328.
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Abstract In high voltage substations there is an increasing demand for computerized equipment, and automation of operation and supervision. The future primary equipment will provide the possibility to collect more information and to provide better control for improved effectiveness.
Since ABB has got a large customer target, each product must be custom made to fulfil the customers (often from different countries) demands. Later these products will be configured by engineers who may not be familiar with the tools used at ABB. This is a very expensive and time consuming. To solve the problem, ABB was looking for a low cost, easy managed and more advanced replacement.
This report includes an investigation for a function block configuration tool based on Microsoft Visio. The tool is connected to a general database using ODBC for the latest ABB Substation Automation SW platform for protection in power transmission equipment.
The thesis report mainly contains a description of the functions and features that are requested. Then methods used to build the prototype is explained and at the end the result is presented.
At the same time the possibilities and problems that will arise from using ODBC based interface for control and monitoring of real-time systems were investigated.
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Zdeněk, Michal. "Vývoj aplikací nad databází Oracle v prostředí Lotus Notes/Domino, .NET a Java." Master's thesis, Vysoká škola ekonomická v Praze, 2008. http://www.nusl.cz/ntk/nusl-2813.
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Diplomová práce se zaměřuje na propojení databáze Oracle s vývojovými platformami Java, .Net a Lotus Notes/Domino. Po vysvětlení základních principů a technik práce s databází následuje část, která si klade za cíl jednotlivé možnosti propojení porovnat a otestovat. Na všech 3 platformách existují vyspělé propojovací technologie pro práci s databází, mezi nejznámější patří ODBC, JDBC, ADO.NET a LC (Lotus Connectors). Jednotlivé možnosti propojení se na všech třech vývojových platformách značně liší. Společná zůstává jen základní funkcionalita pro práci s databází (sestavení připojení, řízení transakcí, volání SQL příkazů, přenášení základních datových typů a volání uložených procedur). Pro praktické ověření jednotlivých propojovacích produktů byla vyvinuta testovací/benchmark aplikace, která byla z jazyka Java naimplementována i do prostředí .NET (C#) a Lotus Notes/Domino (Lotus Script). Bylo naimplementováno a spuštěno 253 testů na 12 produktech od 8 výrobců. Podkladem pro zpracování diplomové práce a realizaci testů byla dokumentace k těmto systémům a další odborná literatura. Díky těmto testům bylo možné, v rámci možností, porovnání jednotlivých produktů i platforem. Systematické testování a práce s těmito produkty ukázaly, že jednotlivé produkty jsou velmi rozdílné v ceně, kvalitě, výkonu, ale i ve svých specifických funkcích.
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Zou, Hanzheng. "Build an Inventory Tracking System." Thesis, Växjö University, School of Mathematics and Systems Engineering, 2007. http://urn.kb.se/resolve?urn=urn:nbn:se:vxu:diva-1580.
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This thesis paper introduces you about the process of how to build an inventory tracking system in a local Swedish company. The related project is to support the thesis paper, and is also for the company’ using. The software product of this project is an application that works for managing various types’ instruments in the company of SWECO-Vaxjo. It will play an important role in the further management work of the company.
In this thesis paper, the candidate techniques and theories for implementing this system are discussed. And in the end a good solution for this problem will be presented in the paper.
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Кривопуск, О. В. "Розробка web-додатку з підтримки діяльності торгівельної компанії." Thesis, Чернігів, 2021. http://ir.stu.cn.ua/123456789/23049.
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Кривопуск, О. В. Розробка web-додатку з підтримки діяльності торгівельної компанії : випускна кваліфікаційна робота : 123 "Кoмп’ютepнa iнжeнepiя" / О. В. Кривопуск ; керівник роботи В. А. Бичко ; НУ "Чернігівська політехніка", кафедра iнфopмaцiйниx тa кoмп’ютepниx cиcтeм. – Чернігів, 2021. – 55 с.Розроблено веб-додаток для підтримки діяльності компанії. Проведено аналіз існуючих веб-сайтів, розглянуто методи побудови, тестування, експлуатації, модернізації веб-сайтів. Виконано розробку схеми бази даних, блок-схеми авторизації та реєстрації користувачів. Розроблено веб-сайт торгівельної компанії. Реалізовано алгоритми авторизації та реєстрації користувачів на сайті, та механізм додавання новин до сайту. Сайт розроблено за допомогою мови програмування PHP.
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Юрченко, О. О. "Аналіз та розробка програмного забезпечення для оптимізації пропозицій на основі zend framework." Thesis, Київський національний університет технологій та дизайну, 2017. https://er.knutd.edu.ua/handle/123456789/8192.
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Valério, Carlos Alberto da Encarnação. "Sistema de extracção, publicação e análise de informação geográfica." Master's thesis, Universidade de Évora, 2011. http://hdl.handle.net/10174/12191.
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Com o objectivo de generalizar a possibilidade de visualizar e analisar informação geográfica, desenvolveu-se este trabalho que propõe um sistema de extracção, publicação e análise de informação geográfica, tendo como ponto de partida, a independência da fonte de dados e da temática. O trabalho realizado passou por três fases de desenvolvimento, sendo a primeira fase, a criação de uma interface simples e o desenvolvimento de todos os processos de extracção de informação com o recurso a ligações ODBC com as diferentes fontes de dados. A segunda fase teve como objectivo todo o processo intermédio de geração de ficheiros KML e por fim a última fase, que consistiu no processo de publicação da informação, através do recurso a uma ferramenta de visualização e divulgação de informação geográfica, onde a escolha recaiu sobre o Google Earth. O trabalho desenvolvido teve resultados muito interessantes que possibilitam analisar e visualizar informação geográfica, não apenas do projecto no âmbito do qual surgiu (FCOMP-01-0124-FEDER-007360 – Inquirir da Honra: Comissários do Santo Oficio e das Ordens Militares em Portugal (1570 – 1773)) e que até ao momento conseguia a visualização desta mesma informação apenas textualmente, como fornece ferramentas essenciais e de aplicação prática noutros âmbitos similares em diferentes áreas e contextos, trazendo incrementos à informação anteriormente disponível, ao permitir visualizar as variáveis com geo-referenciação sobre mapas de fundo histórico e a cartografia em todo o planeta, sem dificuldade; ### Abstract: With the purpose of opening to the general public the possibility of visualization and analisys of geographic information, this work proposes the development of a system of extraction, publication and analysis of geographic information, based on independent sources and themes. This work has been developed within three stages; the first, creation of an interface and the development of all processes of information extraction based on ODBC connections with the different data sources. In the second stage, KML files were generated based on the previous extracted data, and in the final stage, all information was published with the help of a geographic visualization tool, where the choice was Google Earth. This study was developed over the (FCOMP-01-0124-FEDER-007360 – Inquirir da Honra: Comissários do Santo Oficio e das Ordens Militares em Portugal (1570 – 1773)) Project, in order to improve the resulting data, which was only textual, providing new tools and visualization interface with the increment of the resulting information. The results obtained with this work in the field of geographic visualization were very interesting and showed potencial in multiple purposes, such as geo-mapping over layers of ancient maps and cartography.
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Jandák, Miroslav. "Napojení .NET / Java technologie na SAS BI." Master's thesis, Vysoká škola ekonomická v Praze, 2009. http://www.nusl.cz/ntk/nusl-15551.
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This thesis is focused on SAS Enterprise Intelligence Platform product and it's capabilities to integrate within a Business Intelligence solution. The aim of the thesis is to describe integration technolgies that the platform features, as well as to determine their application field and compare them, eventually add usage examples. The first part of the thesis explains the general concept and architecture of Business Intelligence, afterwards the reader gets familiar with the SAS Enterprise Intelligence Platform, it's stucture and components and it's Business Intelligence market position. The second part of the thesis contains description (how they work and what they are good for) of the integration technologies available in SAS Enterprise Intelligence Platform. Those technologies are mostly implementations of the most common industry standards (database APIs, COM/DCOM, CORBA, web services). The study also includes description of these standards supported by SAS. The thesis features also comparisions of the integration technologies, namely comparison of database API implementations and comparision of Integrated Object Model API with SAS BI Web Services.
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Drake, Fred L. Jr. "odb/Tools Project Report." Thesis, Virginia Tech, 1995. http://hdl.handle.net/10919/36972.
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odb/Tools is a suite of object classes providing scriptable access to the object database facility of ProjectEnvision. It implements an interface to the base ODB library for the Python embeddable language using both a C-language module linked to the host runtime environment and several native Python modules to provide the high level access to the facilityMaster of Science
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Holub, Martin. "Datový standard zdravotnických informačních systémů." Master's thesis, Vysoké učení technické v Brně. Fakulta elektrotechniky a komunikačních technologií, 2010. http://www.nusl.cz/ntk/nusl-218778.
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The diploma thesis "Data Standard of the Health Information Systems" deals with the structure of data standard including XML language. Further the thesis is focusing on hospital information system CLINICOM with the inclusion of the access to data records from its database Caché company InterSystems. Description of the National registers of health is also included.The concept of web application is also one part of the thesis which enables to generate reports in the data standard of the Ministry of Healt of the Czech Republic for mandatory reporting by NHIS registers in the time interval from the Caché database. Found records from the database can be printed for archiving. The work also deals with security access to the HIS server and data communication between health organizations.
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Kutik, Ilʹja Vitalʹevič. "The ode and the odic : essays on Mandelstam, Pasternak, Tsvetaeva and Mayakovsky." Doctoral thesis, Stockholms universitet, Slaviska institutionen, 1994. http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-68065.
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Kutik, Ilʹâ Vitalʹevič. "The Ode and the Odic : essays on Mandelstam, Pasternak, Tsvetaeva and Mayakovsky /." Stockholm : Almqvist och Wiksell, 1994. http://catalogue.bnf.fr/ark:/12148/cb37671636q.
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Slade, Christopher Ryan. "On-Disk Sequence Cache (ODSC): Using Excess Disk Capacity to Increase Performance." Diss., CLICK HERE for online access, 2005. http://contentdm.lib.byu.edu/ETD/image/etd1020.pdf.
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Ghersgorin, Raquel. "A sem-odb application for the western cultures database." FIU Digital Commons, 1998. https://digitalcommons.fiu.edu/etd/3926.
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This thesis presents the evolution of the Western Cultures Database. The project starts with a database design using a Semantic modeling, and continues with the implementation following two techniques: a Relational and a Semantic approach. The project continues with them in parallel, reaching a point where the Relational is left aside because of the advantages of the Semantic (Sem-ODB) approach.
The Semantic implementation produces as a result the Western Culture Semantic Database Application - web interface (the main contribution of this thesis). The database is created and populated using Sem ODB and the web interface is built using WebRG (report generator), HTML, JavaScript and JavaChart (applets for graphical representation). The resulting semantic application permits the storage and retrieval of data, the display of reports and the graphical representation of the data through a Web interface. All of these to support research assertions about the impact of historical figures in Western Cultures.
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Bengtsson, Dan. "Test Process Evaluation by Combining ODC and Test Technique Effectiveness." Thesis, Blekinge Tekniska Högskola, Institutionen för programvaruteknik och datavetenskap, 2001. http://urn.kb.se/resolve?urn=urn:nbn:se:bth-5978.
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This report discusses the importance of test process evaluation in order to improve a test model and to provide developer- and management feedback. The report results in a test evaluation framework, developed in cooperation with a department at Ericsson Software Technology in Karlsrona. The framework is a result of discussions with the developers regarding performed testing, studying defect types from past projects and by analyzing the result from a small survey answered by some of the developers at Ericsson. The overall project aim was to evaluate performed testing in order to improve the test model. This requires a good insight of the test process, which is provided by the developed test evaluation framework. The test process is visualized by extracting test process data, making it possible to achieve the project aim. The project aim can be divided into the three following areas: Firstly to evaluate if the current test model is followed as expected, for example are all test techniques used according to the test model? Secondly to evaluate how well the test model fulfills predefined expectations, i.e. is a defect detected with the expected test technique and in the expected test phase? Finally to evaluate if there are any problematic defects that should receive extra attention during a project such as if one or several defect types occurs more frequently than others? The framework is based on another framework, Orthogonal Defect Classification [Chillarege92], combined with the research area Test Technique Effectiveness. The aim of this combination was to support the developed framework. Further a specific part of the framework is focusing on developer- and management feedback.Dan Bengtsson Västra Stationstorget 7 222 37 Lund
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Fournier, Jessica. "Etude spectroscopique de micro fractures sous surfaciques dans la silice vitreuse dans la gamme proche IR-proche UV." Phd thesis, Université Sciences et Technologies - Bordeaux I, 2011. http://tel.archives-ouvertes.fr/tel-00649867.
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Cette thèse entre dans le contexte des études portant sur l'endommagement laser des optiques en silice utilisées sur le Laser MégaJoule (LMJ) au CEA/CESTA. L'étude par spectroscopie de luminescence des défauts présents dans les micro-fractures sous surfaciques des pièces de silice polie, supposés être à l'origine de l'amorçage de l'endommagement laser, a été choisie pour cette recherche. Les micros fractures étant difficiles à détecter, nous avons créé des fractures modèles en faisant des indentations dans la silice. Une comparaison des spectres de luminescence sous excitation à 325 nm, proche de la longueur d'onde utilisée sur le LMJ, entre les indentations et les dommages laser dont l'analyse a donné lieu à des interprétations indiscutables dans la bibliographie, est proposée. Des expériences de luminescence à basse température ou sur des pièces acidées sont présentées pour compléter les informations obtenues sur les différents défauts observés.
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Goto, Yasuyuki, Kazuko Nishio, Yoshiko Ishida, Sayo Kawai, Tomo Osafune, Mariko Naito, Nobuyuki Katsuda, and Nobuyuki Hamajima. "No Association Between Helicobacter Pylori Seropositivity and Ornithine Decarboxylase (ODC) A317G Polymorphism, and No Modification by NAD(P)H : Qinone Oxidoreductase 1 (NQO1) C609T." Nagoya University School of Medicine, 2007. http://hdl.handle.net/2237/7474.
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Kartberg, Emma. "OCD and Empathy Games : Using empathy games to inform the public about ODC." Thesis, Högskolan i Skövde, Institutionen för informationsteknologi, 2019. http://urn.kb.se/resolve?urn=urn:nbn:se:his:diva-17846.
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This research focuses on obsessive-compulsive disorder (OCD) and how games focused on making the player feel empathy (empathy games) can increase the public’s general knowledge of the disorder. The disorder is currently commonly misunderstood and is not always taken seriously, something that potentially could hurt those with OCD. The stigma surrounding OCD sometimes makes people avoid getting the help they need, making them suffer in silence. The objective of the research was to define several game design principles that suggests what a developer should focus on when making an empathy game about OCD with the purpose to inform the general public. This was done by analyzing several scientific articles discussing either OCD or empathy games, and concluding the most important parts from them into game design principles. Four game design principles were found; target audience, reality, clarity, and includation. These have not been tested in a practical setting, but can possibly serve as guidelines when making an empathy game focusing on OCD.
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Silva, Mariane Arnoldi da. "Papel das poliaminas periféricas no desenvolvimento da dor inflamatória em ratos." Universidade Federal de Santa Maria, 2010. http://repositorio.ufsm.br/handle/1/11131.
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Conselho Nacional de Desenvolvimento Científico e TecnológicoPolyamines (putrescine, spermidine and spermine) are aliphatic amines produced by the action of ornithine descarboxylase (ODC), a rate-limiting and protein kinease C (PKC)-regulated step in polyamine synthesis. Since the levels of polyamines were found to be high in synovial fluid of arthritic patients, the aim of the present study was to identify the role of peripherally produced polyamines in the model of inflammatory pain induced by adjuvant arthritis. The subcutaneous injection of complete Freund s adjuvant (CFA, 50 μL/paw) caused the development of mechanical allodynia and edema. Moreover, it increased ODC expression and activity as well as PKC activation. The previous administration of the selective ODC inhibitor DFMO (10 μmol/paw) was capable of preventing the development of allodynia and edema as well as the increase in ODC activity produced by CFA injection. Furthermore, the previous administration of the PKC inhibitor GF109203X (1 nmol/paw) reduced allodynia and the increase of ODC activity in animals injected with CFA. Accordingly with the synthesis inhibition, we have observed that subcutaneous injection of putrescine (10 μmol/paw), spermidine (3-10 μmol/paw) or spermine (0.3-3 μmol/paw) into the rat paw also caused mechanical allodynia and edema. The present results suggest that endogenously synthesized polyamines are involved in the development of nociception and edema caused by the adjuvant. Moreover, the polyamine production in inflammatory site seems to be related with the increase in ODC activity stimulated by PKC activation. Thus, the control of polyamine synthesis and action could be an interesting target to control inflammatory pain.
Poliaminas (putrescina, espermidina e espermina) são aminas alifáticas produzidas pela ação da ornitina descarboxilase (ODC), enzima limitante e proteína quinase C (PKC), passo regulatório da síntese de poliaminas. Desde que níveis elevados de poliaminas foram encontrados no fluído sinovial em pacientes com artrite, o objetivo do presente estudo foi investigar a produção de poliaminas perifericamente em modelo de dor inflamatória induzido por CFA. A injeção subcutânea do adjuvante completo de Freund (CFA, 50 μL/pata) causou o desenvolvimento de alodínia mecânica e edema, bem como um aumento na expressão e atividade da ODC e na ativação da PKC. A administração prévia do inibidor seletivo da ODC, o DMFO (10 μmol/pata), foi capaz de prevenir o desenvolvimento da alodínia e edema, bem como o aumento da atividade produzida pela injeção de CFA. Além disso, a pré-administração do inibidor da PKC o GF109203 (1 nmol/pata), reduziu a alodínia e o aumento da atividade da ODC em animais injetados com CFA. De acordo com a inibição da síntese, também observamos que a injeção subcutânea de putrescina (10 μmol/pata), espermidina (3-10 μmol/pata) ou espermina (0,3-3 μmol/pata) na pata de ratos desenvolveu alodínia mecânica e edema. O presente estudo sugere que as poliaminas sintetizadas endogenamente estão envolvidas no desenvolvimento da nocicepção e edema causado pelo CFA. Além disso, as poliaminas produzidas nos sítios de inflamação estão relacionadas com o aumento na atividade da ODC estimulada pela ativação da PKC. Assim, o controle da síntese das poliaminas e função poderia ser um interessante alvo para o controle da dor inflamatória.
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Manhães, Marcelo Mota. "Classificação e resolução de defeitos em manutenção de software utilizando ODC e histórico de soluções." Universidade Tecnológica Federal do Paraná, 2014. http://repositorio.utfpr.edu.br/jspui/handle/1/1004.
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Nos dias atuais, com o aumento da demanda de serviços de suporte, como, por exemplo, no campo da alta disponibilidade e do desempenho para o cliente e da demanda de custos mais baixos para as empresas de manutenção e hospedagem de software, a resolução de incidentes de software em um tempo menor junto ao cliente e a prevenção de defeitos tornaram-se um tópicos fundamentais. Além disso, a atividade de manutenção de software é uma das fases que consome mais tempo, esforço e consequentemente custo no ciclo de desenvolvimento de software. Balancear eficiência e custo torna-se um desafio para qualquer empresa de suporte em manutenção de software. A abordagem utilizada nesta pesquisa estabelece um processo para classificar defeitos e delinear um conjunto de melhores soluções para os defeitos classificados a partir do histórico de defeitos e a base de conhecimento do cliente. Esta classificação também separa complexidade de problemas para serem gerenciados pelo time de suporte mais adequado. O método base utilizado é o ODC (Classificação Ortogonal de Defeitos) e extensões voltadas ao suporte de software são propostas e utilizadas. Por meio desta pesquisa, é possível verificar se a classificação e associação de soluções podem acarretar em uma redução no tempo de atendimento dos incidentes de suporte. Foi observado em quatro amostras de dois clientes diferentes (X e Y) que utilizando a classificação dos defeitos, direcionamento correto aos times de suporte e agrupamento de soluções, promoveu uma redução no tempo de atendimento em 70% dos incidentes de suporte no cliente Y e 92,5% dos incidentes de suporte para o cliente X. A redução de tempo foi obtida pela redução no número de transferências entre os times de suporte e a redução de incidentes. O processo apresentado é incremental, pois é baseado no aumento das informações históricas e na eficácia das soluções propostas. Este método de soluções pode favorecer a redução dos recursos necessários para suportar sistemas computacionais em provedores de serviço.Nowadays with the increasing of demand in support services such as high availability and performance faced by customers and low cost operations to software maintenance and hosting enterprises, the resolution of software incidents in less time and defect prevention turned a key point. Moreover, the software maintenance is one most time consuming and effort demanding and by consequence cost in software development life cycle. Balancing effectiveness and costs turn a challenge to any enterprise that manages support in software maintenance. The approach used on this research defines a process to classify defects and boundary a set of best solutions associated to these classes from defects history and customer knowledge base. Also this classification separates different problem complexities that can be handled to different support teams. The base method used is the ODC (Orthogonal Defect Classification). With this research is possible to verify that the classification and solutions associations with problem class can undertake a time reduction in incidents resolution in software maintenance. It was verified using four service provider samples in two different customers (X and Y) that classification of defects, correct support team redirection and best solution grouping helps on reduction of incidents resolution time between 70% of incidents to customer Y and 92,5 % of incidents to customer X. The reduction was reached with reduction in number of transfers between supporting teams and incidents number reduction. The process is incremental because it is unfolded from history information and from effectiveness into solutions purposed. This process can leverage human resources nedded to support computational systems in service providers.
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Reynolds, Jonathan James. "Structure-based drug discovery against a novel antimalarial drug target, S-adenosylmethionine decarboxylase/ornithine decarboxylase." Diss., University of Pretoria, 2012. http://hdl.handle.net/2263/27172.
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Malaria is one of the most life-threatening diseases affecting mankind, with over 3 billion people being at risk of infection, with most of these people living in Africa, South America and Asia. As the malaria parasite is rapidly becoming resistant to many of the possible treatments on the market, it is of upmost importance to identify new possible drug targets and describe drugs against these that are inexpensive, easy to manufacture and have a long shelf-life in order to combat malaria. One such target is the polyamine pathway. The polyamines putrescine, spermidine, and spermine are crucial for cell differentiation and proliferation. Interference with polyamine biosynthesis by inhibition of the rate-limiting enzymes ornithine decarboxylase (ODC) and S-adenosylmethionine decarboxylase (AdoMetDC) has been discussed as a potential chemotherapy of cancer and parasitic infections. Usually, both enzymes are individually transcribed and highly regulated as monofunctional proteins. However, ODC and AdoMetDC from P. falciparum (PfODC and PfAdoMetDC, respectively) are found as a unique bifunctional protein (PfAdoMetDC/ODC) in the malaria parasite, making it an enticing target for new, selective antimalarial chemotherapies. In order to apply structure-based drug discovery strategies to design inhibitors for PfAdoMetDC/ODC, the atomic resolution structures of these proteins are needed. Each individual domain has had its structure proposed through homology modelling; however atomic resolution structures of these domains are not yet available. The homology model of PfAdoMetDC/ODC has not yet been elucidated due to the interactions between the domains of the bifunctional protein not being fully understood. High levels of recombinant expression of the bifunctional protein have been either unsuccessful or resulted in the formation of insoluble proteins being produced. The purpose of this project is to optimise the recombinant expression of PfAdoMetDC/ODC, and the PfODC domain, to produce high yields of pure, soluble protein for subsequent atomic resolution structure determination. Ultimately, this will enable the utilisation of PfAdoMetDC/ODC in structure-based drug discovery strategies. Overexpression of P. falciparum proteins in E. coli is notoriously difficult, mainly due to the codon bias between the two species. Comparative studies were performed on four constructs of the PfAdoMetDC/ODC gene, containing either the wild-type, fully codon harmonised, or partially codon harmonised gene sequences to analyse the effect codon harmonisation had on protein expression and activity of both domains of PfAdoMetDC/ODC as well as on the monofunctional PfODC domain. Codon harmonisation did not improve the expression levels or the purity of recombinantly expressed PfAdoMetDC/ODC or the monofunctional PfODC domain. Truncated versions of both proteins, and contamination by the E. coli chaperone proteins DnaK and GroEL, were present in the protein samples even after purification by affinity chromatography. However, codon harmonisation improved the activity levels of the PfAdoMetDC domain, while decreasing the activity of the PfODC domain of PfAdoMetDC/ODC. Harmonisation of the monofunctional PfODC domain resulted in a decrease in the activity of the protein. In order to identify possible inhibitors of the PfODC domain of the bifunctional protein, a structure-based drug discovery study was initiated based on a homology model for PfODC. Four hundred compounds with known antimalarial activity were virtually screened against the PfODC homology model and the top two scoring compounds were selected for enzyme inhibition assays based on their predictive binding affinity against the enzyme, and two medium scoring compounds were selected as controls. Enzyme inhibition studies were performed on the bifunctional PfAdoMetDC/ODC to determine the effect the compounds had on both domains of the protein. Of the compounds assayed one of the compounds significantly reduced the activity levels of both domains of PfAdoMetDC/ODC. Additionally, one compound significantly reduced the activity level of the PfAdoMetDC domain of PfAdoMetDC/ODC. This work therefore contributes towards characterisation of the unique PfAdoMetDC/ODC in malaria parasites as a novel drug target.Dissertation (MSc)--University of Pretoria, 2012.
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Jiménez, Álvarez Luis Gonzalo. "Diseño y Especificación del ocio digital con fines de aprendizaje ODFA Subproblema: Ocio digital formativo en competencias ODFC para la UCE." Doctoral thesis, Universidad de Alicante, 2021. http://hdl.handle.net/10045/115210.
Full textAbstract:
El desarrollo humano en la sociedad digital debe ser integral, una alternativa, es la fusión del ocio formal y los recursos digitales que generan el ocio digital, al añadirle el aprendizaje (individual y colaborativo) se forja el ocio digital con fines de aprendizaje ODFA, de este modelo se desprenden varios subproblemas, uno de ellos es el ocio digital formativo en competencia ODFC y su instancia denominada ocio digital formativo que integra competencias ODFIC, constituyendo en nuevas alternativas para enseñar y aprender. La investigación tiene como objetivos: establecer los fundamentos conceptuales y el estado del arte, establecer la especificación funcional y estructural del ODFA, realizar actividades de diseño del ODFC y el ODFIC, controlar y contribuir a la valorización del ocio digital, analizar los datos estadísticos sobre el ODFA y establecer un plan de acción para la Universidad Central del Ecuador UCE. La metodología como proceso de investigación utilizó el método causal formal MCF y el análisis estadístico descriptivo. Antes de construir un edificio se requiere los planos, igualmente, para desarrollar un software para el ODFA previamente se diseña y especifica el sistema, para ello se aplicó el MCF que permite identificar el problema y darle solución [1]. Se estableció que la conjetura (hipótesis inicial) es: “con el ocio digital es posible obtener conocimiento ubicuo para aprender o crear”. La finalidad es especificar y diseñar sistemas de ocio digital para ayudar al aprendizaje que se motiva porque se quiere sacar provecho docente al ocio digital y porque se quiere buscar estrategias para producir aprendizaje en tiempo libre. Posteriormente, se determinó la especificación funcional, estructural y contextual. Aplicando el modelado, dentro del conjunto de las “actividades en ocio digital” se determinó el modelo ODFA, que es el empleo formativo de sistemas digitales en tiempo libre. Se establecieron los objetivos o “para qué” siguientes: explotar el esfuerzo, el tiempo, el factor de complacencia, los rasgos específicos que tiene el ocio digital y ampliar el desarrollo curricular con aprendizaje ubicuo con fines docentes, uso recreativo de los recursos digitales con aprendizaje, ocio digital incorporado a la teoría de la educación, cubrir competencias curriculares, avanzar en la organización escolar, control y valorización del ocio digital. Dado lo extenso del proyecto ODFA, se resolvieron los tres últimos objetivos a través de los “cómo” o módulos siguientes: ODFC, ODFIC, FODA, rastreando y evaluando la actividad, promoviendo la percepción social sobre el ocio digital, gestionando la trazabilidad de los procesos del ODFC y apoyando académica y económicamente al ocio digital formativo, además, se analiza los “con qué” o los componentes de la solución. Adicionalmente se generan los grafos que indican la funcionalidad del problema y subproblemas. En la parte contextual se responden a las cuestiones: ¿cuándo?, ¿quién?, ¿cuánto?, ¿dónde? ¿a quienes? La aportación científica está en avanzar en la identificación de modelos, potenciar la resolución de problemas y la toma de decisiones en el marco del ODFA, en justificar el ocio como “scholé”, describir los recursos digitales orientados al aprendizaje, en plantear que el ODFA se alinea al “constructivismo conectado” a través del MCF que siendo usado en el diseño y especificación de sistemas también permite investigar conocimiento conocido (aprender) y generar conocimiento nuevo (crear) en forma ubicua. El ODFA involucra a la institución universitaria, docentes, el currículo, las actividades de los discentes (actores principales), el rastreo, la evaluación, el MCF (con el soporte de la App Mayéutica) y la ética. Mientras que el subproblema ODFC como una asignatura plantea potenciar las habilidades y capacidades, el ODFIC como un proyecto integrador de varias disciplinas propone la integración de las competencias: resolución de problemas, colaboración, creación y comunicación. Se concluye que el ODFA no solo plantea la transformación de la estrategia educativa sino que agrega valor reflexivo al proceso de aprendizaje con base a la “escuela digital” y “constructivismo conectado”, en este marco, el subproblema ODFC potencia las competencias gracias a MCF fuera de lo tradicional, fortalece el autoaprendizaje formal dirigido por el docente, porque lo que cuenta es la percepción observacional e intelectual hacia la causalidad a fin de comunicar los resultados, inventos o prototipos con objetividad de forma individual o grupal.
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Casali, Valesca Veiga Cardoso. "Padrões de atividade da ornitina decarboxilase (ODC) e sua regulação hormonal sob estresse de temperatura em Anastrepha fraterculus (Diptera, Tephritidae)." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2005. http://hdl.handle.net/10183/5159.
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Ornitina decarboxilase (ODC) (EC 4.1.1.17) é a primeira enzima que desencadeia a síntese das poliaminas putrescina, espermidina e espermina nas células. As poliaminas são cátions alifáticos envolvidos no controle de crescimento e são requeridas para uma variedade de eventos biológicos como síntese de proteína, replicação do DNA e divisão celular. No presente estudo, a atividade da ODC foi medida em ovo, larva, pupa, fêmea jovem e adulta de Anastrepha fraterculus. Durante o desenvolvimento de A. fraterculus, a atividade da ODC apresentou flutuações. Entre os estágios anteriores à emergência, o ovo teve a mais alta atividade específica, provavelmente devido à embriogênese que é caracterizada pela alta taxa de divisão celular. A atividade da ODC foi também altamente significativa em ovários e corpo gorduroso de fêmeas jovens possivelmente devido ao avanço da oogênese e vitelogênese. Parâmetros cinéticos (Km app e Vmax) para atividade da ODC foram determinados em pupa, larva e ovário de fêmeas jovens e apresentaram grande variação. A guanosina trifosfato (GTP) demonstrou afetar grandemente estes parâmetros cinéticos, sugerindo estarem ocorrendo modificações pós-traducionais. Fêmeas jovens (4 dias) de A. fraterculus também foram analisadas quanto ao efeito do estresse de temperatura (6ºC e 20/6ºC) e da aplicação tópica do hormônio juvenil isolados ou em conjunto. . Os principais resultados foram que a concentração de 500 ng e os tempos de incubação de 3, 7 e 18 horas aumentaram a atividade da ODC. As fêmeas mantidas a 6ºC e 20/6ºC tiveram atividade da ODC mais alta do que as fêmeas mantidas a 25ºC. O tempo de incubação de 1 hora com o HJ aumentou a atividade da ODC no tratamento de 6ºC, quando comparado com fêmeas mantidas apenas com o estresse de temperatura sem a adição do hormônio (controle). No entanto, no tratamento das fêmeas mantidas a 20/6ºC, somente os tempos de 3 e 18 horas de incubação com o HJ demonstraram aumento na atividade da ODC quando comparadas com o tempo de incubação de 1 hora e com as fêmeas mantidas sem a adição do hormônio (controle). Os machos não apresentaram diferença na atividade da ODC quando submetidos ao estresse de temperatura de 6ºC, mas as medidas do apódema ejaculatório foram maiores a 25ºC que a 6ºC. Estes resultados podem ser considerados como parte de um processo adaptativo a mudanças ambientais. Por último, observamos que as medidas dos ovários (comprimento e largura) de fêmeas jovens mantidas com o inibidor da ODC, -difluormetilornitina (-DFMO; 50mM) são diferentes significativamente quando comparadas com às medidas das fêmeas controle sem o inibidor. O conjunto desses resultados indica a importância da relação entre ODC, HJ e estresse de temperatura para a A. fraterculus. Como esta mosca é uma das piores pragas para a fruticultura brasileira, estes dados, além de contribuírem para um maior conhecimento de sua biologia básica, poderão também ser usados para a escolha de melhores estratégias de controle populacional.
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Dukas, Kostantinos. "Etude et régulation de l'expression des proto-oncogènes c-Ki-ras et ODC dans les cellules pancréatiques tumorales AR4-2J." Toulouse 3, 1995. http://www.theses.fr/1995TOU30040.
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L'identification des proto-oncogenes impliques dans la transduction des signaux mitogenes a ete determinante dans la comprehension des mecanismes qui controlent la croissance tumorale. Dans ce travail nous avons etudie l'expression des proto-oncogenes c-ki-ras et odc (ornithine decarboxylase) dans la lignee pancreatique tumorale de rat ar4-2j. Pour cela, nous avons developpe une methodologie de reverse transcription-polymerase chain reaction qui permet l'amplification, simultanee et avec la meme efficacite, de plusieurs arnm meme lorsque leurs niveaux sont tres differents. Nos resultats suggerent que ces proto-oncogenes, actives par un mecanisme de sur-expression genique, sont impliques dans le phenotype tumoral des cellules ar4-2j. De plus, ils jouent un role important dans la transduction du signal mitogene puisqu'ils sont induits durant la phase exponentielle de croissance cellulaire et que leur expression est stimulee par les facteurs de croissance, egf (facteur de croissance de l'epiderme) et gastrine. Par ailleurs, ces facteurs de croissance stimulent l'expression des proto-oncogenes nucleaires c-fos et c-myc. Par contre, la somatostatine, agent antiproliferatif sur ce modele cellulaire, inhibe leur expression. La mesure des quantites de proteines p21#c#-#k#i#-#r#a#s et de l'activite enzymatique de l'odc confirment les phenomenes transcriptionnels observes. Bien que les mecanismes intracellulaires de leur regulation transcriptionnelle ne soient pas encore elucides, le fait que l'ensemble des facteurs etudies stimulent et/ou inhibent des reactions de tyrosine phosphorylation suggere que celles-ci sont impliquees. Cependant, les voies proteine kinase c-, phospholipase a#2- et ampc-dependantes peuvent etre des mediateurs de leur regulation transcriptionnelle. Enfin, l'utilisation d'oligonucleotides anti-sens phosphorothioates stabilises et diriges contre le proto-oncogene c-ki-ras suggere que les proteines p21#c#-#k#i#-#r#a#s constituent un intermediaire de la cascade d'evenements conduisant a la proliferation terminale tandis que l'odc peut representer un element de transduction en aval de p21#r#a#s
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Irmscher, Thomas. "Orthogonal defect classification als QM in der SW-Erstellung Vorstellung, Implementierung und Evaluation der ODC in der SW-Entwicklung für Fluggeräte." München AVM, 2010. http://d-nb.info/1001972503/04.
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Dobesch, Aleš. "Optický D/A převodník pro VLC aplikace." Doctoral thesis, Vysoké učení technické v Brně. Fakulta elektrotechniky a komunikačních technologií, 2017. http://www.nusl.cz/ntk/nusl-364609.
Full textAbstract:
Disertační práce se zabývá optickým digitálně-analogovým převodníkem, jako alternativou optické části koncové vysílací jednotky (optický front-end) určené pro VLC (visible light communication) aplikace. Stěžejní část práce, která se věnuje numerickému modelování optického kanálu, prezentuje vliv bitové hloubky, topologie koncové části optického vysílače a geometrického uspořádání na přenášený signál. Součástí práce je návrh, realizace a ověření parametrů optického digitálně-analogového převodníku vycházející z předcházejících simulací. V poslední řadě práce obsahuje demonstraci vysokorychlostní optické komunikace s využitím navrženého VLC optického vysílače.
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Lavergne, Christopher Leon Joseph. "Peri-Ovulatory Supplementation of L-Ornithine to Increase Reproductive Success in Aged Mice." Thesis, Université d'Ottawa / University of Ottawa, 2018. http://hdl.handle.net/10393/38341.
Full textAbstract:
In all mammalian species examined thus far, the ovaries produce a burst of ornithine decarboxylase (ODC) and putrescine during ovulation or after application of a bolus of human chorionic gonadotropin (hCG). Aged mice are deficient in this peri-ovulatory ODC and putrescine burst. Moreover, peri-ovulatory putrescine supplementation in aged mice increases egg quality and reduces miscarriage rates. These studies suggest that peri-ovulatory putrescine supplementation may be a simple and effective therapy for reproductive aging for women. However, putrescine has never been used in humans and, currently no pure source of putrescine is suitable for human trials. Given that ODC is highly expressed in the ovaries during ovulation but otherwise exhibits low activity in most tissues, we hypothesized that L-ornithine, the substrate of ODC, might be a better alternative. In this study, we have demonstrated that systemic application of L-ornithine increased ovarian putrescine levels; the increase was restricted to animals that had been injected with hCG. Furthermore, L-ornithine specifically increased ovarian putrescine levels without affecting putrescine levels in most other tissues. Unfortunately, thus far peri-ovulatory L-ornithine supplementation in mouse drinking water produced mixed effects on reproductive outcome in aged mice. Therefore, our studies demonstrated the potential of L-ornithine supplementation as a possible therapy for aging-related infertility, but further work is required to produce an effective application method.
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DELACROIX, CATHERINE. "Mesure du contenu mineral osseux vertebral par absorptiometrie biphotonique : etude de la reproductibilite du densitometre oris-odc 200 ; determination des valeurs normales et du seuil fractuaire." Amiens, 1988. http://www.theses.fr/1988AMIEM087.
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Diado, Aleksandra. "Využití PCR pro druhovou identifikaci a pro vyhledávání vybraných genů laktobacilů." Master's thesis, Vysoké učení technické v Brně. Fakulta chemická, 2016. http://www.nusl.cz/ntk/nusl-240520.
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Probiotic food products - food additives contain different species of probiotic bacteria. Accurate species identification with their characteristics is very important from the view of products quality. Methods of DNA diagnostics are used for these purposes. In this thesis DNA was isolated from 4 probiotic products. The presence of bacterial of genus Lactobacillus and species L. acidophilus, L. casei, L. plantarum, L. rhamnosus were detected in three products by PCR. This information was in accordance with the data provided by the manufacturer. Two sets of primers were used for identification of species. Using other primers sequences of genes such as bsh, lai and odc were detected in DNA isolated from the products. Differences were estimated among products concerning the detection of lai gene Lactobacillus acidophilus.
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Oliveira, J?lio C?sar Melo Gomes de. "Soft sensor veicular para medi??o de emiss?es de gases." PROGRAMA DE P?S-GRADUA??O EM ENGENHARIA EL?TRICA E DE COMPUTA??O, 2017. https://repositorio.ufrn.br/jspui/handle/123456789/24834.
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Historicamente as cidades seguem modelos de planejamento reativos onde o gestor toma decis?es conforme a ocorr?ncia dos problemas. Por outro lado, o crescimento exponencias das Tecnologias da Informa??o e Comunica??o (TIC) tem permitido que diversos sensores, dispositivos, sistemas e objetos se conectem, gerando dados que podem ser transformados em informa??o e usados em um paradigma de planejamento urbano mais eficiente onde as decis?es podem ser tomadas antes que os problemas ocorram. Assim, nesse trabalho ser? desenvolvido um software capaz de estimar a quantidade de di?xido de carbono, a partir de leituras de sensores existentes em ve?culos, que ir? contribuir para o planejamento proativo das cidades a partir do monitoramento da polui??o veicular. T?cnicas de CrowdSensing e um leitor On-Board Diagnostic (OBD-II) ser?o utilizados para extrair dados dos ve?culos em tempo real, armazenados localmente nos aparelhos que foram coletados. Por fim, podemos ver que a partir das informa??es obtidas, existe a possibilidade de se extrair informa??es a respeito do funcionamento do ve?culo e at? mesmo realizar infer?ncias sobre a din?mica dos ve?culos nas cidades, mostrando potencial para o desenvolvimento de ferramentas auxiliares a gest?o dos centros urbanos.
Traditionally, cities planning has followed reactive decision models based on the occurrence of problems. With the development and spread of communication and information technologies, the interconnection of electronic devices has opened a new era of data exchanging and processing, potentially supporting more efficient decisions in modern cities. This paper then proposes a software, capable of estimating the amount of carbon dioxide from existing sensor readings in vehicles, which aims to support more proactive planning and management of modern cities, addressing the problem of vehicular pollution monitoring. For that, a crowdsensing approach and the OBD-II standard are exploited to dynamically extract data from vehicles to be processed and delivered. Finally, we can see that with the information obtained, it is possible to extract information about the operation of the vehicle and even make inferences about the dynamics of the vehicles in the cities, showing potential for the development of auxiliary tools for the management of urban centers .
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Birkholtz, Lyn-Marie. "Molecular characterisation of the ornithine decarboxylase gene of the human malaria parasite, plasmidium falciparum." Diss., University of Pretoria, 1998. http://hdl.handle.net/2263/37299.
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Malaria is one of the most serious tropical infectious diseases affecting mankind. The
prevention of the disease is hampered by the increasing resistance of the parasite to
existing chemotherapy and -prophylaxis drugs. The need for novel therapeutic targets
and drugs is therefore enormous and the understanding of the biochemistry of the parasite
is imperative. The aim of this study was the identification and molecular characterisation
of the eDNA of one such metabolic target protein, ornithine decarboxylase (ODC), in the
human malaria parasite P. falciparum.
The P. falciparum ODC eDNA was isolated by means of a modified RT-PCR technique,
RACE. No sequence data were available and the primers used were based on consensus
areas identified in the protein sequences from other related organisms. The isolation and
identification of the eDNA with degenerate primers was successful in 3' -RACE, but
necessitated the optimisation of the eDNA synthesis protocol and the use of total RNA as
starting material. The sequence obtained facilitated the application of 5' -RACE with
ODC-specific primers based on the 3' -RACE sequence data. The full-length ODC
eDNA sequence was obtained by overlap-alignment of various segments. A novel
suppression PCR technology was applied during the 5' -RACE in order to create an
uncloned eDNA library of amplified cDNAs representing only the mRNA population. The P. falciparum ODC eDNA contains an open reading frame of ---2847 bp and
translates to a large 939 amino acid protein. The protein contained large internal
insertions and was extended by '""273 N-terminal residues compared to ODCs from other
organisms. Several possible signature motifs were identified for phosphorylation,
glycosylation and transamidation. The P. falciparum ODC protein seems to contain more
hydrophilic and a-helix forming residues. These characteristics should be further
investigated after expression of the recombinant protein.
The isolation of the P. falciparum ODC eDNA facilitates the validation of this protein as
an antimalarial target.Dissertation (MSc)--University of Pretoria, 1998.
gm2014
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Brun, Christophe. "ETUDE DE COMPOSES QUASI-UNIDIMENSIONNELS A ONDE DE DENSITE DE CHARGE PAR MICROSCOPIE A EFFET TUNNEL." Phd thesis, Université Paris Sud - Paris XI, 2006. http://tel.archives-ouvertes.fr/tel-00126135.
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Ce travail s'inscrit dans le cadre de l'étude des systèmes physiques de basse dimension. Nous présentons une étude des propriétés électroniques locales de deux composés quasi-unidimensionnels (Q1D) à onde de densité de charge (ODC), le bronze bleu Rb0.3MoO3 et NbSe3, par microscopie à effet tunnel (STM), sous ultra-haut vide (UHV) et à basse température. Ces matériaux ont été clivés in-situ suivant leur plan naturel, (-201) pour Rb0.3MoO3 et (100) pour NbSe3. Notre étude montre que la distribution spatiale de surface des ODC peut être qualitativement différente de celle du volume et qu'une préparation in-situ des surfaces de ces composés est nécessaire pour avoir accès à leurs propriétés électroniques véritables. En surface de Rb0.3MoO3, l'ODC a été visualisée par STM. Un phénomène nouveau a été observé: la composante qb=2kf du vecteur d'onde de l'ODC n'est pas homogène en surface. Nous proposons que ces déviations résultent d'inhomogénéités de surface du vecteur de Fermi, dues à la distribution inhomogène des atomes alcalins sur la surface, après clivage du matériau. Les implications de ces résultats sont discutées. Nos mesures STM sur NbSe3 offrent une première étude cohérente des états ODC q1 et q2, et de leur distribution spatiale sur les différentes chaînes de la structure. A basse température, l'existence d'une interaction entre les ODC q1 et q2 est révélée par l'apparition d'une nouvelle superstructure. Enfin, tandis que l'ODC q1 possède en surface une température de transition (Tc) comparable à celle du volume, l'ODC q2 possède une Tc de 10 à 15K plus élevée en surface. Différents mécanismes reposant sur des effets spécifiques de surface sont discutés.
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Reinicke, Michael. "Dienstauswahlverfahren im Grid /." Göttingen : Sierke, 2007. http://www.gbv.de/dms/zbw/52764790X.pdf.
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Li, Xiaolin. "An Empirical Examination of Factors Affecting Adoption of An Online Direct Sales Channel by Small and Medium-Sized Enterprises." Kent State University / OhioLINK, 2008. http://rave.ohiolink.edu/etdc/view?acc_num=kent1214531897.
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Djoko, Kamwa Ghislain. "Fluctuations supracondictrices dans les conducteurs organiques quasi-1D." Mémoire, Université de Sherbrooke, 2007. http://savoirs.usherbrooke.ca/handle/11143/4778.
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L'origine des déviations observées aux basses températures sur la conductivité des matériaux organiques quasi-1D reste à ce jour contreversée. Il est établi pour ces matériaux que les fluctuations magnétiques y sont présentes. L'objectif visé par notre travail est d'évaluer l'influence des fluctuations supraconductrices induites par l'antiferromagnétisme dans les conducteurs quasi-1D. Il ressort de nos calculs que la paraconductivité à un canal (Cooper), calculée à partir du courant de paires coïncide à celle d'Aslamazov-Larkin. Pour une dimension spatiale donnée, plus l'anisotropie est prononcée plus les fluctuations deviennent importantes. Dans le cas quasi-1D avec mélange des canaux de Cooper et de Peierls, on retrouve le résultat d'Aslamazov-Larkin à une constante près. Nos résultats s'accordent qualitativement aux données expérimentales avec un paramètre d'anisotropie fortement influencé par la pression. De même, on remarque que la pression lorsqu'elle augmente diminue les fluctuations supraconductrices. En outre l'interférence des canaux augmente la conductivité des conducteurs organiques quasi-1D de manière significative.
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Lamalice, André. "En temps de guerre comme en temps de paix, gouvernement manquant, gouvernance manquée : la protection civile au Canada, 1938-1988." Thesis, Université d'Ottawa / University of Ottawa, 2011. http://hdl.handle.net/10393/19839.
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À travers l'étude des cinquante premières années de l'histoire de la protection civile au Canada, le présent travail discute de la capacité et de la volonté politique de gouvernements nationaux successifs d'assurer la sécurité de la population en temps de crises et d'urgences. Cette thèse soutient qu'à l'exclusion d'un bref intermède au plus fort de la Guerre froide, la fonction de protection civile ne parviendra pas à s'imposer au
nombre des priorités de la gouvernance canadienne au cours de cette période. Entre la création administrative d'un sous-comité sur les précautions contre les raids aériens à la veille de la Seconde Guerre mondiale, qui marque les débuts de la fonction de protection civile au Canada, et l'adoption en 1988 de la Loi sur la protection civile, un demi-siècle s'écoule. L'histoire de cette fonction se développe en réaction à l'évolution du contexte international et au gré des impératifs politiques, économiques et sociaux nationaux qui marquent la seconde moitié du XXe siècle. Sa généalogie emprunte à la défense nationale à la fois le vocabulaire et la structure. Longtemps confondue dans la forme et dans le fond à la défense civile, la protection civile en arrive
tard dans le siècle à se défaire de ses origines imposées et à se forger une personnalité propre orientée vers la gestion des urgences. Néanmoins, comme le démontre le présent travail, son évolution est marquée par d'importantes failles de gouvernance qui se traduisent inter alia par une mise en oeuvre aléatoire du système canadien de protection civile, l'absence continue d'un cadre législatif national, le développement de politiques fédérales inconsistantes, voire même à certaines périodes incohérentes, un financement trop souvent déficient et une direction indécise qu'exprime une série quasi ininterrompue de transferts administratifs et de réorganisations successives. Le présent travail en conclut que ces failles de gouvernance ont empêché l'atteinte d'un état de préparation national à la hauteur du mandat premier du gouvernement qui est d'assurer la sécurité de ses citoyens en temps de guerre comme en temps de paix.
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Lan, Xin Shan, and 藍新善. "A distributed transactional service for ODBC databases in windows NT environments." Thesis, 1995. http://ndltd.ncl.edu.tw/handle/90091125968917788293.
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Lan, Hsin-Shan, and 藍新善. "A Distributed Transactional Service for ODBC Databases in Windows NT Environments." Thesis, 1995. http://ndltd.ncl.edu.tw/handle/29210435540422721724.
Full textAbstract:
碩士國立交通大學
資訊科學學系
83
The main goal of our system is to provide a common user interface to users who used to use a particular database management system (DBMS) and its Structured Query Language (SQL) grammar. This user interface makes it possible that users can access different DBMS without spending time to learn the different interface and grammar between different DBMS. Our system also provide the functionality, users can access different DBMS files from hosts. The Open DataBase Connectivity (ODBC), Microsoft*s plays an important role on making it possible that integrating different DBMS. In the following chapters, I'll introduce what is ODBC and the detail of our implementation.
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羅雲忠. "The Implementation of a Logic Programming Interface for accessing RDB via ODBC." Thesis, 1997. http://ndltd.ncl.edu.tw/handle/46473624740098515371.
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碩士國立成功大學
工程科學研究所
85
Prolog is the language used widely in artificial intelligence (AI). If we can extend the ability of Prolog to access general database systems, two benefits can be found. First, we can use the power of DBMS to manage more facts and to reduce the cost of developing programs using mumerous data. Second, the DBMS can use the power of Prolog to build front-end programs that need AI technique, such as data mining or natural language interface, etc. The purpose of this thesis is to consider the problems in connecting Prolog programs with the relational database management systems (RDBMS). These problems include the relationship between Prolog and RDBMS, the transformation from Prolog language to SQL, and the relevant function about database management. After considering the system structure of deductive database systems (DDB) and three-tier structure in distributive environment, we design an interface that Prolog application program can easily access the data in the general RDBMS. This structure is based on open database connectivity (ODBC). After the adequate transformation, we hope that the part of dealing with database can be collected in one place and the front end program can concentrate on the part of not dealing with database. Then the application structure of Prolog programs can be more modular and uniform but great flexibility.
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Zeng, Zun-Ren, and 曾俊仁. "A study of middleware roles under client/server computing environment : ODBC & DB-library." Thesis, 1995. http://ndltd.ncl.edu.tw/handle/77134126955958047765.
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曾俊仁. "A study of Middleware roles Under Client/Server Computing Environment -ODBC & DB-Library." Thesis, 1994. http://ndltd.ncl.edu.tw/handle/91468484976907487104.
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碩士國立臺灣科技大學
機械工程研究所
83
Despite the increasing maturity of the client/serverchnology, the interaction between the front-end applicationd back-end servers is still a "black box" often beyond aogrammer's understanding. Program developers dealing withient/server architecture utilize limited functions of newhcnologies. If the overall efficiency of a application systemscomes undesirable, developers often cannot seek an effectivelution and locate the blind spot which affects the efficiencythe application programs, since they are restricted by thenctions of the middleware incorporated in the programvelopment tools. This study adopts an analytical approach and selects SQLrver of SYBASE/Micorsoft as the back-end server, and Visualsic 3.0 and PowerBuilder 4.0 as the front-end tools. Theudy also utilizes two types of middleware with differentaracteristics, such as the common ODBC(Open DataBasennectivity) and native DB-Library. The major goal is toscuss their operations and settings to locate factorsffecting the overall efficiency of a system, so as tofer suggestions and methods to program developers to helpprove their system efficiency.
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Боднар, Микола Орестович, and Mykola Bodnar. "Розробка автоматизованої системи управління для санаторію-профілакторію «Барвінок» Зборівського району." Bachelor's thesis, 2021. http://elartu.tntu.edu.ua/handle/lib/35741.
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Об’єкт аналізу – медичні інформаційні системи. Мета роботи – проектування автоматизованої системи санаторію-профілакторію, розробка програмного забезпечення до задачі створення АІС, пошуку інформації в БД.
Основні результати – АІС, сучасні комп’ютерні технології, БД. Розроблена теоретична модель проекту автоматизованої системи ведення ведення обліку санаторію-профілакторію. Розроблена структурна схема модулів системи, схема бази даних. Проведений аналіз існуючих медичних інформаційних систем. Розроблені завдання виконано засобами Delphi та Access. Розроблено програмне забезпечення до задачі збереження та редагування даних, пошуку інформації.The object of analysis is medical information systems. The purpose of work - designing of the automated system of sanatorium-dispensary, development of the software to a task of creation of AIS, search of the information in a DB. The main results - AIS, modern computer technology, database. The theoretical model of the project of the automated system of conducting the account of sanatorium-dispensary is developed. The structural scheme of modules of system, the scheme of a database is developed. The analysis of existing medical information systems is carried out. The developed tasks were performed using Delphi and Access. Developed software for the task of saving and editing data, information retrieval.
ВСТУП 10 РОЗДІЛ 1. АНАЛІЗ ПРЕДМЕТНОЇ ОБЛАСТІ 11 1.1 Теоретичне обґрунтування 11 1.2 Важливість дизайну бази даних 12 1.3 Життєвий цикл розробки баз даних 13 1.4 Методи проектування баз даних 14 1.5 Основи проектування БД 17 1.6 Висновок до першого розділу 25 РОЗДІЛ 2. ПРАКТИЧНА РЕАЛІЗАЦІЯ 26 2.1 Огляд систем керування базами даних 26 2.2 Огляд медичних інформаційних систем 27 2.3 Опис об’єкту автоматизації 29 2.3.1 Характеристика предметної області 29 2.4 Структурна схема розроблюваної системи 32 2.4.1 Постановка задачі 32 2.4.2 Опис функціональної структури автоматизованої підсистеми 33 2.5 Реалізація системи 39 2.5.1 Модель бази даних в Delphi 39 2.5.2 Створення таблиці 39 2.5.3 Програма управління базою даних 42 2.5.4 Механізм з'єднання з сховищем даних ADO 44 2.5.5 Приклад зв'язку з Access через ADO 45 2.6 Демонстрація та результати роботи системи 46 2.7 Висновок до другого розділу 49 РОЗДІЛ 3. БЕЗПЕКА ЖИТТЄДІЯЛЬНОСТІ, ОСНОВИ ХОРОНИ ПРАЦІ 50 3.1 Гігієнічні вимоги до організації обладнання робочих місць з ВДТ 50 3.2 Дія електричного струму на організм людини, види електротравм 51 3.3 Безпека життєдіяльності в екстремальних умовах 54 3.4 Наслідки забруднення навколишнього середовища 57 ВИСНОВКИ 61 ПЕРЕЛІК ЛІТЕРАТУРНИХ ДЖЕРЕЛ 62
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Gibson, Lindsay Gail. "Wordsworth and the odic tradition /." 2009. http://hdl.handle.net/10288/1167.
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Tsai, Hong-Je, and 蔡宏哲. "The preliminary research of measurement of two-dimensional peri- odic flow." Thesis, 1993. http://ndltd.ncl.edu.tw/handle/34773560589888687718.
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Wu, Yi-Ting, and 吳易庭. "Identify the binding partners of ODC-AZ1 complex in the 19S proteasome." Thesis, 2016. http://ndltd.ncl.edu.tw/handle/62348803817314536311.
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碩士國立中興大學
生命科學系所
104
Human ornithine decarboxylase (hODC) is the key enzyme for polyamine synthesis in mammals. The function of ODC is catalyzing ornithine to putrescine and then releasing carbon dioxide. Active ornithine decarboxylase is a homodimer. ODC is an ubiquitin-independent enzyme through a degradation process without ubiquitination, and antizyme (AZ) can bind to ODC to inhibit it activity and promote the ubiquitin-independent degradation by 26S proteasome. The 26S proteasome can be divided into two parts: 19S and 20S, the function of 20S is protein degradation; the function of 19S is regulation. The 19S is composed of many Rpn proteins, we found some candidate Rpn protein which could combine with ODC and AZ to affect ODC degradation rate in reticulocyte lysate : Rpn1, Rpn2, Rpn8, Rpn10, Rpn11, and Rpn13. In our results of degradation, (1) Rpn8 didn’t influence on ODC or AZ degradation； (2) Rpn10 and high concentration of Rpn2 and Rpn13 can increase ODC degradation rate; (3) additionally found that both Rpn2 and Rpn13 can retard AZ degradation rate, and further experiment found the reason is that Rpn2 is the main factor and Rpn13 is the secondary factor. Using analytical ultracentrifuge (AUC) for analysis, the Rpn2 and Rpn13 can interact with each other, but ODC or AZ can’t interact with Rpn proteins. Using enzyme activity assay, we can observe whether Rpn10 can disrupt ODC dimer to lose ODC enzyme activity. The result showed that Rpn10 has no influence on ODC enzyme activity. Therefore, our study provides three subunits, Rpn2, Rpn10, and Rpn13 on 19S proteasome, mediate the ODC degradation in an AZ-dependent and ubiquitin-independent pathway.
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Origanti, Sofia S. "Multiple mechanisms of ODC regulation by activated Ras studies in an epithelial cell model /." 2007. http://etda.libraries.psu.edu/theses/approved/WorldWideIndex/ETD-1793/index.html.
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Nölke, Greta [Verfasser]. "Engineering and characterization of single chain antibody fragments (scFvs) specific to key enzymes in polyamine biosynthesis and manipulation of polyamine pathway by constitutive expression of recombinant ODC and SDE enzymes in transgenic tobacco / vorgelegt von Greta Nölke." 2002. http://d-nb.info/965683427/34.
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