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Relevant bibliographies by topics / Odorant/xenobiotic metabolism

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Journal articles
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Academic literature on the topic 'Odorant/xenobiotic metabolism'

Author: Grafiati

Published: 20 July 2024

Last updated: 31 July 2025

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Journal articles on the topic "Odorant/xenobiotic metabolism"

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Rogers, M. E., M. K. Jani, and R. G. Vogt. "An olfactory-specific glutathione-S-transferase in the sphinx moth Manduca sexta." Journal of Experimental Biology 202, no. 12 (1999): 1625–37. http://dx.doi.org/10.1242/jeb.202.12.1625.

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Insect antennae have a primary function of detecting odors including sex pheromones and plant volatiles. The assumption that genes uniquely expressed in these antennae have an olfactory role has led to the identification of several genes that are integral components of odorant transduction. In the present study, differential display polymerase chain reaction (ddPCR) was used to isolate 25 antennal-specific mRNAs from the male sphinx moth Manduca sexta. Northern blot analyses revealed that one clone, designated G7-9, was antennal-specific and was highly enriched in male antennae relative to fem

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2

Boichot, Valentin, Franck Menetrier, Jean-Michel Saliou, et al. "Characterization of human oxidoreductases involved in aldehyde odorant metabolism." Scientific Reports 13, no. 1 (2023). http://dx.doi.org/10.1038/s41598-023-31769-4.

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AbstractOxidoreductases are major enzymes of xenobiotic metabolism. Consequently, they are essential in the chemoprotection of the human body. Many xenobiotic metabolism enzymes have been shown to be involved in chemosensory tissue protection. Among them, some were additionally shown to be involved in chemosensory perception, acting in signal termination as well as in the generation of metabolites that change the activation pattern of chemosensory receptors. Oxidoreductases, especially aldehyde dehydrogenases and aldo–keto reductases, are the first barrier against aldehyde compounds, which inc

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Shirai, Tomohiro, Dan Takase, Junkichi Yokoyama, et al. "Functions of human olfactory mucus and age-dependent changes." Scientific Reports 13, no. 1 (2023). http://dx.doi.org/10.1038/s41598-023-27937-1.

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AbstractOdorants are detected by olfactory sensory neurons, which are covered by olfactory mucus. Despite the existence of studies on olfactory mucus, its constituents, functions, and interindividual variability remain poorly understood. Here, we describe a human study that combined the collection of olfactory mucus and olfactory psychophysical tests. Our analyses revealed that olfactory mucus contains high concentrations of solutes, such as total proteins, inorganic elements, and molecules for xenobiotic metabolism. The high concentrations result in a capacity to capture or metabolize a speci

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4

Godoy, Ricardo, Ana Mutis, Leonela Carabajal Paladino, and Herbert Venthur. "Genome-Wide Identification of Aldehyde Oxidase Genes in Moths and Butterflies Suggests New Insights Into Their Function as Odorant-Degrading Enzymes." Frontiers in Ecology and Evolution 10 (February 8, 2022). http://dx.doi.org/10.3389/fevo.2022.823119.

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Aldehyde oxidases (AOXs) are common detoxifying enzymes in several organisms. In insects, AOXs act in xenobiotic metabolism and as odorant-degrading enzymes (ODEs). These last appear as crucial enzymes in the life cycle of insects, helping to reset their olfactory system, particularly in lepidopterans, which fulfill important ecological roles (e.g., pollination or destructive life cycles). A comprehensive understanding of their olfactory system has provided opportunities to study key chemosensory proteins. However, no significant advance has been made around lepidopteran AOXs research, and eve

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5

Yang, An-Jin, Ning-Na Yin, Dan-Lu Chen, Yu-Ruo Guo, Yu-Jie Zhao, and Nai-Yong Liu. "Identification and characterization of candidate detoxification genes in Pharsalia antennata Gahan (Coleoptera: Cerambycidae)." Frontiers in Physiology 13 (September 16, 2022). http://dx.doi.org/10.3389/fphys.2022.1015793.

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The wood-boring beetles, including the majority of Cerambycidae, have developed the ability to metabolize a variety of toxic compounds derived from host plants and the surrounding environment. However, detoxification mechanisms underlying the evolutionary adaptation of a cerambycid beetle Pharsalia antennata to hosts and habitats are largely unexplored. Here, we characterized three key gene families in relation to detoxification (cytochrome P450 monooxygenases: P450s, carboxylesterases: COEs and glutathione-S-transferases: GSTs), by combinations of transcriptomics, gene identification, phyloge

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Dissertations / Theses on the topic "Odorant/xenobiotic metabolism"

1

Mérignac-Lacombe, Jeanne. "Approches innovantes dans la caractérisation des enzymes du métabolisme des xénobiotiques dans les muqueuses nasales : du modèle animal à l’ingénierie tissulaire." Electronic Thesis or Diss., Bourgogne Franche-Comté, 2024. http://www.theses.fr/2024UBFCI003.

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La sensibilité de notre odorat dépend des enzymes du métabolisme des xénobiotiques (EMX). Non seulement les EMX détoxifient la muqueuse nasale mais elles arrêtent aussi le signal olfactif pour en permettre la détection d’un nouveau. Parfois appelées enzymes du métabolisme des odorants (EMO), certaines participent aussi à la genèse de nouveaux métabolites odorants. L’objectif de cette thèse était d’étudier les EMX nasales en utilisant deux modèles innovants respectant au mieux les principes éthiques des 3R (Remplacement, Réduction, Raffinement des expérimentations animales). Alors que les expla

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