Academic literature on the topic 'Offending agent'

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Journal articles on the topic "Offending agent"

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Kam, April J., Alex F. Manini, and Lewis S. Nelson. "First, Remove the Offending Agent." American Journal of Cardiology 102, no. 3 (2008): 370–71. http://dx.doi.org/10.1016/j.amjcard.2008.04.005.

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Godlovitch, Stan. "Offending against Nature." Environmental Values 7, no. 2 (1998): 131–50. http://dx.doi.org/10.1177/096327199800700201.

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Some environmental views characterise the human abuse of nature as an offence against nature itself. What conception of nature would best fit that characterisation? To focus upon such a conception, aesthetic offences against nature are examined and distinguished at the outset from moral offences. Aesthetic offences are divided into those internal to our cultural outlook and external to it. The external outlook, conceiving nature as a thing wholly apart from us, is shown to be necessary to any view of nature being offended against. Central to the external outlook is a conception of nature as th
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Keshmiri, Hesam, Anuj Behal, Shawn Shroff, and Charles Berkelhammer. "Clopidogrel-Induced Severe Hepatitis: A Case Report and Literature Review." Case Reports in Hepatology 2016 (2016): 1–4. http://dx.doi.org/10.1155/2016/8068276.

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Clopidogrel is a commonly prescribed antiplatelet agent that carries a rare risk of hepatotoxicity. We describe a case of severe clopidogrel-induced hepatitis with liver biopsy assessment. Prompt recognition and withdrawal of the offending agent are imperative to prevent progression and potentially fatal liver injury.
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Thompson, Brittany M., Joshua M. Brady, and Jeffrey D. McBride. "Bridging the Gap between Dermatology and Psychiatry: Prevalence and Treatment of Excoriation Disorders Secondary to Neuropsychiatric Medications." Psych 5, no. 3 (2023): 670–78. http://dx.doi.org/10.3390/psych5030043.

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(1) Background: The dermatillomania and trichotillomania disorders in this study refer to the subcategory of obsessive-compulsive disorders (OCDs) that are medication-induced. Patients with typical dermatillomania or trichotillomania disorder generally present with other OCD symptoms, although this is not present in the cases of medication-induced skin picking or hair pulling disorders found in the current literature. This paper serves to investigate the prevalence and treatment methods of medication-induced excoriation disorders. (2) Methods: The PubMed database was queried for cases of medic
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Blyth, Dana, Elizabeth Markelz, and Jason Okulicz. "Cutaneous leukocytoclastic vasculitis associated with levofloxacin therapy." Infectious Disease Reports 4, no. 1 (2012): 11. http://dx.doi.org/10.4081/idr.2012.e11.

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Many cases of cutaneous vasculitis are druginduced with histology revealing leukocytoclastic vasculitis (LCV). We present a case of levofloxacin- associated LCV successfully treated with prednisone and cessation of the offending drug. Although case reports describe a link between LCV and older fluoroquinolones, such as ciprofloxacin and ofloxacin, recent reports have implicated the newer fluoroquinolone levofloxacin. Recognition of fluoroquinoloneinduced cutaneous vasculitis is important as continuation or re-exposure of the offending agent may have life-threatening consequences.
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Vucicevic Boras, Vanja, Vlaho Brailo, Ana Andabak Rogulj, Danica Vidovic Juras, Dragana Gabric, and Danko Velimir Vrdoljak. "Oral Adverse Reactions Caused by Over-the-Counter Oral Agents." Case Reports in Dentistry 2015 (March 26, 2015): 1–4. http://dx.doi.org/10.1155/2015/196292.

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Over-the-counter products rarely cause unwanted reactions in the oral cavity. Oral reactions to these agents are not specific and might present with various clinical oral findings. Detailed medical history is a key to the proper diagnosis of these lesions and fortunately other diagnostic procedures are rarely needed. Lesions are usually managed with elimination of the offending agent and with topical steroids. In more severe cases systemic steroids should be applied.
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Dr., Rajkumar Kothiwal, Rakesh Yadav Dr., Deepak S. Bohra Dr., et al. "Trends of steroid modified tinea at tertiary care hospital in India." International Multispeciality Journal of Health 3, no. 7 (2017): 263–67. https://doi.org/10.5281/zenodo.837991.

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<strong><em>Abstract—</em></strong>Dermatophytes are the common fungal agents implicated in superficial skin infections worldwide, commonly known as tinea. They include species of Trichophyton, Microsporum and Epidermophyton. Infections of this organism have dramatically increased in last one decade by misuse of topical corticosteroids cream alone or in combination with topical antibacterial and antifungal agents. So this study was conducted with the aim to study about culprits (prescribers) and various offending agents. This study was conducted on 1239 consecutive patients of tinea between ag
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Dr., Rajkumar Kothiwala, Deepak S. Bohra Dr., Rakesh Kumar Dr., et al. "Alarming tropical steroid misuse on face: A descriptive study." Alarming tropical steroid misuse on face: A descriptive study 3, no. 7 (2017): 210–14. https://doi.org/10.5281/zenodo.837290.

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<strong>Abstract—</strong> Acne vulgaris is a chronic inflammatory disease of the pilosebaceous unit. The clinical lesions are non-inflammatory open and closed comedones and or papules, pustules and nodules of varying degree of inflammation and depth. A lot of steroid, cosmetic and Ayurvedic products containing unlabeled depigmenting agent and steroids are available readily over the counter sale. The side effects of these products are not documented and can lead to adverse effects of continuous usage. This study was aimed to find out various offending depigmenting agents (topical unlabeled ste
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Arshad, Hafiz, Arsalan Khan, Usama Assad, Muaiad Kittaneh, and Charles Berkelhammer. "Antihistamine-Induced Hepatitis: 2 Cases Involving Loratidine." Case Reports in Hepatology 2016 (2016): 1–2. http://dx.doi.org/10.1155/2016/6890313.

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Antihistamine-induced hepatitis is rare. We present 2 cases of antihistamine-induced hepatitis with autoimmune features, caused by loratidine. One case was confirmed by rechallenge. Identifying and discontinuing the offending agent are essential for treatment.
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Williams, DR, and RJ Stark. "Intravenous Lignocaine (Lidocaine) Infusion for the Treatment of Chronic Daily Headache with Substantial Medication Overuse." Cephalalgia 23, no. 10 (2003): 963–71. http://dx.doi.org/10.1046/j.1468-2982.2003.00623.x.

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Patients with chronic daily headache with medication overuse are difficult to treat, especially when the doses of analgesia are substantial. We have previously shown that intravenous lignocaine (lidocaine) infusion is useful in maintaining pain control while the offending analgesic agent is withdrawn in these patients. The published data on long-term efficacy of this treatment is limited. We undertook a retrospective survey of 71 consecutive patients admitted for lignocaine infusion (mean 8.7 days) for treatment of chronic daily headache, with substantial analgesic abuse. Ninety percent of pat
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Dissertations / Theses on the topic "Offending agent"

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Birks, Daniel J. "Computational Agent-Based Models of Offending: Assessing the Generative Sufficiency of Opportunity-Based Explanations of the Crime Event." Thesis, Griffith University, 2012. http://hdl.handle.net/10072/367327.

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This thesis demonstrates that agent-based modelling offers a viable compatriot to traditional experimental methodologies for criminology scholars, that can be applied to explore the divide between micro-level criminological theory and macro-level observations of crime; and in turn, aid in the assessment of those theories which aim to describe the crime event. The following overarching research question is addressed: Are the micro-level mechanisms of the opportunity theories generatively sufficient to explain macroscopic patterns commonly observed in the empirical study of crime? Drawing on the
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Kuyumcuoglu, Simone. "Från kriminalitet till hederlighet : Att förstå vägarna ut ur den kriminella livsstilen." Thesis, Stockholms universitet, Institutionen för socialt arbete - Socialhögskolan, 2019. http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-174722.

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Aim: The aim of this study was to identify and interpret former criminal delinquents experiences of what internal, social and structual factors are contingent on the process of change in offending. Method: A qualitative method was used with a hermeneutic approach. A qualitative inquiry was conducted through three semi-structured life story interviews with former criminal delinquents working on an organization that specifically strives to help delinquents to desist from crime.  The mode of analysis utilized in this study was the concept of turning points and a life course perspective which are
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Books on the topic "Offending agent"

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Cohen, Jeffrey A., Justin J. Mowchun, Victoria H. Lawson, and Nathaniel M. Robbins. A 28-Year-Old Male with Weakness in the Setting of Cancer. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780190491901.003.0016.

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Chemotherapy-induced peripheral neuropathy is a common complication of cancer therapy. The diagnosis is generally straightforward, based on the temporal association of symptoms with the offending agent. However, it can sometimes take on a different form of severe, fulminant neuropathy and must be differentiated from other neurologic conditions that occur in the setting of cancer. Particular care must be taken in the patient with clinical indicators of longstanding, hereditary neuropathy as these can confer a distinctive susceptibility to neurotoxicity. The diagnosis relies on an index of suspi
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Welch, Mary R., and Craig Nolan. Chemotherapy and Radiation Therapy. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199937837.003.0143.

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Neurotoxicity is a common problem in oncology practice and neurologists who care for cancer patients encounter a wide range of symptoms attributable to the side effects of radiation and/or chemotherapy. Complications involving the nervous system may be debilitating. Though generally improved by dose reduction or cessation of an offending agent, such symptoms can be irreversible and frequently have a profound impact on quality of life. The appropriate balance between therapeutic efficacy and drug or radiation toxicity requires close attention to the patient’s complaints as well as a thorough un
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Becker, Jeffrey. Nutraceutical Treatments for Addiction Recovery. Edited by Shahla J. Modir and George E. Muñoz. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190275334.003.0020.

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Current medical treatment in substance-use disorders and addiction recovery often fails to address the underlying molecular pathophysiologic mechanisms of addiction morbidity. Psychopharmacology and behavioral interventions do not directly address the cellular patterns of dysfunction in addiction but natural treatments can and should be employed in a research-based manner to support existing treatment protocols. Research into addiction pathophysiology is clear: removing the offending agent through sobriety is often not enough to restore natural premorbid physiology. Drug-induced oxidative stre
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Izzedine, Hassan, and Victor Gueutin. Drug-induced acute tubulointerstitial nephritis. Edited by Adrian Covic. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199592548.003.0084.

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Drug-induced acute tubulointerstitial nephritis (ATIN) is the most common aetiology of ATIN and a potentially correctable cause of acute kidney injury (AKI). An interval of 7–10 days typically exists between drug exposure and development of AKI, but this interval can be considerably shorter following re-challenge or markedly longer with certain drugs. It occurs in an idiosyncratic and non-dose-dependent manner. Antibiotics, NSAIDs, and proton pump inhibitors are the most frequently involved agents, but the list of drugs that can induce ATIN is continuously increasing. The mechanism of renal in
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Book chapters on the topic "Offending agent"

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Abeykoon, Jithma P., Omar M. Abu Saleh, and Candido E. Rivera. "Thrombocytopenia." In Mayo Clinic Infectious Disease Case Review, edited by Larry M. Baddour, John C. O’Horo, Mark J. Enzler, and Rahul Kashyap. Oxford University Press, 2021. http://dx.doi.org/10.1093/med/9780190052973.003.0030.

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Drug-induced thrombocytopenia (DITP) is commonly attributed to antimicrobial agents; 153 drugs are believed to have a high probability of causing immune-mediated thrombocytopenia. Rifampin is categorized as a definite cause of DITP. Median time to presentation with thrombocytopenia after rifampin exposure is 1 to 2 weeks. DITP in current medical practice largely remains a clinical diagnosis. The therapy for DITP is discontinuation of the offending agent. Although DITP is associated with a high incidence of morbidity and mortality, the possibility of completely reversing it by discontinuing the
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Ali, Farwa, and Eelco F. M. Wijdicks. "Serotonin Syndrome." In Mayo Clinic Critical and Neurocritical Care Board Review, 2nd ed., edited by Eelco F. M. Wijdicks, Rodrigo Cartin-Ceba, William D. Freeman, Alice Gallo de Moraes, and Richard A. Oeckler. Oxford University Press, 2025. https://doi.org/10.1093/med/9780197628638.003.0075.

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Abstract Serotonin syndrome is a clinical toxidrome due to effects of excess serotonergic neurotransmission in the central and peripheral nervous systems. Symptom severity ranges from mild to severe and life-threatening. Treatment is focused on removal of the offending agent and supportive care primarily with sedation, neuromuscular paralysis, hydration, and serotonin antagonism with cyproheptadine. Serotonin syndrome must be distinguished from other similarly appearing toxidromes.
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Khalil, Sarwat, and Omar M. Abu Saleh. "Dermatology Crisis." In Mayo Clinic Infectious Disease Case Review, edited by Larry M. Baddour, John C. O’Horo, Mark J. Enzler, and Rahul Kashyap. Oxford University Press, 2021. http://dx.doi.org/10.1093/med/9780190052973.003.0040.

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Cutaneous reactions after antibiotic use most commonly present as exanthematous drug eruptions (80% of cases) or urticarial reactions (5%-10%). They can, however, manifest as severe cutaneous reactions (&lt;1 per 1,000 new cases) that are associated with severe, diffuse mucocutaneous involvement and severe systemic symptoms. The 3 most important drug reactions to consider are drug rash with eosinophilia and systemic symptoms, Stevens-Johnson syndrome and toxic epidermal necrolysis, and acute generalized exanthematous pustulosis. Diagnosis is confirmed histopathologically. Symptoms resolve rapi
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Koratala, Abhilash, Girish Singhania, and A. Ahsan Ejaz. "Tubulointerstitial Nephropathies." In Kidney Protection, edited by Vijay Lapsia, Bernard G. Jaar, and A. Ahsan Ejaz. Oxford University Press, 2019. http://dx.doi.org/10.1093/med/9780190611620.003.0043.

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Tubulointerstitial nephropathies encompass diverse disease processes involving the part of the renal parenchyma that consists of the tubules and interstitium. Tubulointerstitial diseases can occur as primary or secondary (to a systemic disease) processes, and patients can present with either acute or chronic disease. Depending on the offending agent, the disease may have a particular predilection for the proximal tubules, the distal tubules, or both. Definitive diagnosis is by renal biopsy, which typically reveals variable degrees of cellular infiltration of the interstitium, tubular atrophy,
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McTernan, Emily. "The limits of justified offence." In On Taking Offence. Oxford University PressNew York, 2023. http://dx.doi.org/10.1093/oso/9780197613092.003.0005.

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Abstract This chapter examines a series of potential limits on when offence could be justified. First, in the face of a common focus on anger as the apt response to injustice, the chapter carves out a space for offence as one way to directly resist a particular form of injustice. Second, one may think that whether taking offence is justified depends upon whether an agent intended to offend, or is otherwise culpable for the offending act, but this chapter defends blame and offence as separate, if sometimes overlapping, social practices. Third, the chapter explores the claim that disagreement ov
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Pereboom, Derk. "Love and Freedom." In Wrongdoing and the Moral Emotions. Oxford University Press, 2021. http://dx.doi.org/10.1093/oso/9780192846006.003.0006.

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Chapter 6 contends that love and relationships need not be compromised if we, motivated by ethical considerations and skepticism about free will, relinquished the retributive emotions. When we are wronged in relationships, there are non-retributive emotions available to us, whose expressions can play the relevant roles. These emotions include feeling hurt or shocked or disappointed about what the offending agent has done, and sadness or sorrow and concern for him, and taking on the stance of moral protest against him. Personal relationships might presuppose free will due to being structured by
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McAllister, Peter. "Treatment of Chronic Migraine and Medication Overuse Headache." In Comprehensive Review of Headache Medicine, 2nd ed., edited by Morris Levin. Oxford University PressNew York, 2025. https://doi.org/10.1093/med/9780190888770.003.0021.

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Abstract Chronic migraine (CM) is a more aggressive and disabling form of migraine compared to episodic migraine (EM). The definition of CM has evolved during the past two decades; it is currently defined as 15 days or more of headache per month, of which at least 8 are migraines. Many persons with CM overuse acute medications and are at risk for medication overuse and medication overuse headache (MOH). Principles of CM treatment overlap with those of EM, including trigger identification and elimination, stress reduction, and other lifestyle modification. Virtually all CM patients should be of
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Roger, Simon D. "Acute interstitial nephritis." In Oxford Textbook of Medicine, edited by John D. Firth. Oxford University Press, 2020. http://dx.doi.org/10.1093/med/9780198746690.003.0489.

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Acute interstitial nephritis (AIN) is an inflammation of the tubules and interstitium within the kidney, associated with a relatively sudden onset and rapid decline in renal function. It is usually secondary to drugs (antibiotics, nonsteroidal anti-inflammatory drugs, and proton pump inhibitors being most commonly incriminated), with other causes being infections (classically streptococcal, but this is now less common) and immune disorders (systemic lupus erythematosus, sarcoidosis, and tubulointerstitial nephritis with uveitis). Clinical features—the diagnosis of AIN should be considered in a
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Thomas, Kyle J. "Rational Choice, Gang Membership, and Crime." In The Oxford Handbook of Gangs and Society. Oxford University Press, 2024. http://dx.doi.org/10.1093/oxfordhb/9780197618158.013.9.

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Abstract Rational choice perspectives derive from the standard economic idea that individuals choose to engage in actions when the marginal benefits exceed the marginal risks and costs. Although there is considerable support for rational choice predictions across a range of outcomes related to crime, scholars have rarely invoked choice ideas when explaining issues related to gang involvement. The chapter discusses the foundations of a rational choice model of gang involvement, gang offending and gang disengagement. This perspective differs from traditional sociological views which focus on “ca
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Eid, Abdulmunaim M., and William G. Ondo. "Dopamine Antagonist-Induced Parkinsonism." In Movement Disorders in Psychiatry, edited by Antonio L. Teixeira, Erin Furr Stimming, and William G. Ondo. Oxford University PressNew York, 2022. http://dx.doi.org/10.1093/med/9780197574317.003.0003.

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Abstract Drug-induced parkinsonism (DIP) can be defined as parkinsonism (at least two of four cardinal features) occurring in temporal relationship to medications known to lessen dopaminergic functioning. In fact, one of the first suggestions that dopamine may be involved in the pathogenesis of Parkinson’s disease was based on observing the effects of reserpine, a dopamine depleter, on movements. Individual susceptibility, genetic factors, older age, female sex, and higher doses of offending drugs that have more affinity to D2/D3 receptor for longer durations are known risk factors. However, t
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