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1

Gaines, Alan. "Olfactory Disorders." American Journal of Rhinology & Allergy 27, no. 3_suppl (2013): S45—S47. http://dx.doi.org/10.2500/ajra.2013.27.3898.

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2

Gros, A., V. Manera, C. A. De March, et al. "Olfactory disturbances in ageing with and without dementia: towards new diagnostic tools." Journal of Laryngology & Otology 131, no. 7 (2017): 572–79. http://dx.doi.org/10.1017/s0022215117000858.

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AbstractBackground:Olfactory disorders increase with age and often affect elderly people who have pre-dementia or dementia. Despite the frequent occurrence of olfactory changes at the early stages of neurodegenerative disorders such as Alzheimer's disease, olfactory disorders are rarely assessed in daily clinical practice, mainly due to a lack of standardised assessment tools. The aims of this review were to (1) summarise the existing literature on olfactory disorders in ageing populations and patients with neurodegenerative disorders; (2) present the strengths and weaknesses of current olfact
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3

Snow, James B. "Clinical Investigation of Disorders of Olfaction." American Journal of Rhinology 2, no. 4 (1988): 145–48. http://dx.doi.org/10.2500/105065888781692970.

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The receptor cells in the olfactory neuroepithelium are regularly replaced and, when injured, regenerate from basal cells and reestablish their central connections. This process of reconstitution occurs throughout the life span after mechanical, chemical, and infectious injury. The history and physical findings in association with the quantification of the olfactory loss allow an etiologic diagnosis in many patients. Olfactory losses can be categorized as transport or sensorineural defects. Therapy for transport olfactory losses is frequently effective in restoring the sense of smell. Reasonab
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4

Ziuzia-Januszewska, Laura, and Marcin Januszewski. "Pathogenesis of Olfactory Disorders in COVID-19." Brain Sciences 12, no. 4 (2022): 449. http://dx.doi.org/10.3390/brainsci12040449.

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Since the outbreak of the SARS-CoV-2 pandemic, olfactory disorders have been reported as a frequent symptom of COVID-19; however, its pathogenesis is still debated. The aim of this review is to summarize the current understanding of the pathogenesis of smell impairment in the course of COVID-19 and to highlight potential avenues for future research on this issue. Several theories have been proposed to explain the pathogenesis of COVID-19-related anosmia, including nasal obstruction and rhinorrhea, oedema of the olfactory cleft mucosa, olfactory epithelial damage either within the olfactory rec
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5

Peyvandi, Aliasghar, Shahrokh Khoshsirat, Narges Bazgir, et al. "Olfactory dysfunction as a diagnostic and prognostic marker for movement disorders." Annals of Movement Disorders 7, no. 3 (2024): 171–80. https://doi.org/10.4103/aomd.aomd_75_24.

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Abstract Olfactory dysfunction (OD) is a common nonmotor symptom observed in several movement disorders. The severity and pattern of olfactory impairment vary among these conditions. Notably, olfactory impairment often precedes the clinical diagnosis of movement disorders by several years, yet it remains frequently unrecognized by patients and physicians until formal olfactory tests are undertaken. This review focuses on exploring OD across various movement disorders. A systemic search strategy incorporating key terms such as movement disorders, dystonic disorders, tic disorders, parkinsonian
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6

Lebedeva, G. V., M. V. Svistushkin, L. V. Selezneva, et al. "Possibilities of using the domestic olfactory test in the diagnosis of typical olfactory disorders." Russian Medical Inquiry 8, no. 8 (2024): 470–76. http://dx.doi.org/10.32364/2587-6821-2024-8-8-5.

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Background: the diagnosis of olfactory disorders remains a critical issue in clinical practice. Olfactory testing is the most commonly utilized diagnostic tool. Previously, we developed an olfactory test and validated it on healthy volunteers. Aim: to evaluate the diagnostic efficacy of a domestic olfactory test in detecting various olfactory disorders. Materials and Methods: this study included 100 patients presenting with typical olfactory disorders. Subjects were categorized into three groups: acute rhinosinusitis (AR) (n=50), polypous rhinosinusitis (PR) (n=25), and post-viral olfactory dy
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7

Langstaff, Lorna, Nisha Pradhan, Allan Clark, et al. "Validation of the olfactory disorders questionnaire for English‐speaking patients with olfactory disorders." Clinical Otolaryngology 44, no. 5 (2019): 715–28. http://dx.doi.org/10.1111/coa.13351.

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8

Park, Yong-Jin. "Treatment of the Olfactory Disorders." Journal of Clinical Otolaryngology Head and Neck Surgery 18, no. 1 (2007): 23–27. http://dx.doi.org/10.35420/jcohns.2007.18.1.23.

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9

Ryo, Yusuke, Mina Takeuchi, Naoko Ueda, et al. "Olfactory function in neuropsychiatric disorders." Psychiatry Research 252 (June 2017): 175–79. http://dx.doi.org/10.1016/j.psychres.2017.02.058.

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10

Sirota, P., D. Shamir, and E. Mitrany. "Olfactory sensitivity in eating disorders." Biological Psychiatry 39, no. 7 (1996): 572. http://dx.doi.org/10.1016/0006-3223(96)84195-3.

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11

Clepce, Marion, Karin Reich, Andrea Gossler, Johannes Kornhuber, and Norbert Thuerauf. "Olfactory abnormalities in anxiety disorders." Neuroscience Letters 511, no. 1 (2012): 43–46. http://dx.doi.org/10.1016/j.neulet.2012.01.034.

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12

Friedrich, Hergen, Marco Caversaccio, and Basile Nicolas Landis. "Olfactory disorders after general anesthesia." Journal of Clinical Anesthesia 25, no. 1 (2013): 73. http://dx.doi.org/10.1016/j.jclinane.2012.07.002.

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13

Shetty, Sandeep, Harishnath Vishwanathan, and Sean Carrie. "The management of olfactory disorders." British Journal of Hospital Medicine 68, no. 5 (2007): 241–45. http://dx.doi.org/10.12968/hmed.2007.68.5.23329.

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14

Sirota, Pinkhas, David Shamir, and Edith Mitrany. "Olfactory sensitivity in eating disorders." European Neuropsychopharmacology 6 (June 1996): 13. http://dx.doi.org/10.1016/0924-977x(96)87356-1.

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15

Yang, Jingpu, and Jayant M. Pinto. "The Epidemiology of Olfactory Disorders." Current Otorhinolaryngology Reports 4, no. 2 (2016): 130–41. http://dx.doi.org/10.1007/s40136-016-0120-6.

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16

Ruan, Yang, Xiang-Yu Zheng, Hong-Liang Zhang, Wei Zhu, and Jie Zhu. "Olfactory dysfunctions in neurodegenerative disorders." Journal of Neuroscience Research 90, no. 9 (2012): 1693–700. http://dx.doi.org/10.1002/jnr.23054.

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17

Vladimirova, T. Yu, S. S. Chaplygin, A. V. Kurenkov, E. N. Berkovich, and M. K. Blashentsev. "Modern directions of correction of olfactory disorders in clinical practice." Russian Otorhinolaryngology 22, no. 5 (2023): 69–75. http://dx.doi.org/10.18692/1810-4800-2023-5-69-75.

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Introduction. According to statistics, about 20% of the population have olfactory disorders of various etiologies. Among the older age group, the prevalence of the symptom is significantly higher and ranges from 40% to 65%. Olfactory disorders are most often found in diseases of the nose and paranasal sinuses of viral and infectious genesis and traumatic brain injury. There are currently no approved schemes for the correction of olfactory disorders. However, in chronic rhinosinusitis, the role of endonasal surgical interventions, systemic and topical glucocorticoids, and biological targeted th
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18

Petersen, Marcela Leão, Monia Bresolin, and Ariane Madruga Monteiro. "539 - The association between olfactory dysfunction and psychiatric disorders." International Psychogeriatrics 33, S1 (2021): 82–83. http://dx.doi.org/10.1017/s1041610221002349.

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It is known that olfactory dysfunction occurs early in neurodegenerative diseases, such as Alzheimer’s and Parkinson’s diseases and frontotemporal dementia (FTD). Dementia and psychiatric disorders share a number of clinical features, such as psychosis and depression. As such, misdiagnoses across these conditions are not uncommon. A variety of studies show smell dysfunction in schizophrenia, but little is known about other psychiatric disorders. In order to verify the link between olfaction and psychiatric disorders, a medical literature search was carried out in may 2021 using PubMed, and Coc
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19

Yang, Kun, Carlos Ayala-Grosso, Janardhan P. Bhattarai, et al. "Unraveling the Link between Olfactory Deficits and Neuropsychiatric Disorders." Journal of Neuroscience 43, no. 45 (2023): 7501–10. http://dx.doi.org/10.1523/jneurosci.1380-23.2023.

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Smell loss has caught public attention during the recent COVID-19 pandemic. Research on olfactory function in health and disease gains new momentum. Smell deficits have long been recognized as an early clinical sign associated with neuropsychiatric disorders. Here we review research on the associations between olfactory deficits and neuropathological conditions, focusing on recent progress in four areas: (1) human clinical studies of the correlations between smell deficits and neuropsychiatric disorders; (2) development of olfactory mucosa-derived tissue and cell models for studying the molecu
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20

Vandersteen, Clair, Magali Payne, Louise-Emilie Dumas, et al. "Persistent olfactory complaints after COVID-19: a new interpretation of the psychophysical olfactory scores." Rhinology Online 4 (April 1, 2021): 66–72. http://dx.doi.org/10.4193/rhinol/21.010.

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Background: Sudden olfactory loss is a major symptom of SARS-CoV-2 infection and has a negative impact on daily life quality. Almost 80% of disorders regress spontaneously. No precise characterization of the medium- and long-term olfactory symptoms has been carried out yet, apart from self-assessments. The main objective of this work was to characterize persistent smell disorders in this population. Methodology: Consecutive patients consulting to the ENT department with post-Covid19 olfactory loss were included. The clinical examination included an analog scale for the self-assessment of olfac
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21

Hidalgo, J., G. Chopard, J. Galmiche, L. Jacquot, and G. Brand. "Just noticeable difference in olfaction: a discriminative tool between healthy elderly and patients with cognitive disorders associated with dementia." Rhinology journal 49, no. 5 (2011): 513–18. http://dx.doi.org/10.4193/rhino11.013.

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Olfactory dysfunction appears to be one of the earliest signs of several age-related neurodegenerative disorders, including Alzheimer`s disease (AD) or Parkinson`s disease (PD). To rate performance and olfactory deficits in patients with cognitive disorders, various olfactory tasks have been used such as odor detection, discrimination, recognition memory, identification and naming but no study has been focused on just noticeable difference (JND), a sensitive tool of detection. The aim of this study was to investigate and compare variations in JNDs in healthy elderly and in patients with cognit
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22

Pratama, Yudistira, Anna Mailasari Kusuma Dewi, Muyassaroh, Riece Hariyati, and Willy Yusmawan. "Relationship Between Obesity and Allergies with Olfactory Disorders in Covid-19 Patients." Medica Hospitalia : Journal of Clinical Medicine 10, no. 3 (2023): 319–23. http://dx.doi.org/10.36408/mhjcm.v10i3.949.

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Background: The prevalence of olfactory disorders is around 68% - 85% which occurs in COVID-19 patients with obesity and allergies as risk factors. The abnormalities olfactory pathways can cause by inflammatory response in adipose tissue in obese patients and excessive inflammation due to hyperreactivity of the immune system to allergens in allergic patients. This study aims to analyze the relationship between obesity and allergies to the occurrence of olfactory disorders in COVID-19. Method: It was an observational study during pandemic. Subjects were adult COVID-19 patients in the dr. Kariad
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23

Bhatia-Dey, Naina, and Thomas Heinbockel. "The Olfactory System as Marker of Neurodegeneration in Aging, Neurological and Neuropsychiatric Disorders." International Journal of Environmental Research and Public Health 18, no. 13 (2021): 6976. http://dx.doi.org/10.3390/ijerph18136976.

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Research studies that focus on understanding the onset of neurodegenerative pathology and therapeutic interventions to inhibit its causative factors, have shown a crucial role of olfactory bulb neurons as they transmit and propagate nerve impulses to higher cortical and limbic structures. In rodent models, removal of the olfactory bulb results in pathology of the frontal cortex that shows striking similarity with frontal cortex features of patients diagnosed with neurodegenerative disorders. Widely different approaches involving behavioral symptom analysis, histopathological and molecular alte
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24

Melinte, Gabriela-Violeta, and Codrut Sarafoleanu. "Difficulties of olfactometric evaluation in patients accusing smell disorders after head trauma." Romanian Journal of Rhinology 8, no. 29 (2018): 39–45. http://dx.doi.org/10.2478/rjr-2018-0005.

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Abstract Head trauma is considered to be the third cause of olfactory function disorders. Olfactometric assessment in patients accusing anosmia following head injury produced by car accident or aggression is important, because most of them are involved in law trials in order to obtain financial compensations from the author. It is compulsory to use both subjective and objective olfactory evaluation methods combined with a detailed anamnesis, a complete ENT examination and a good cranio-facial imaging (computed tomography or MRI) in order to exclude malingerers and to obtain an accurate diagnos
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25

Fiorentino, Julie, Magali Payne, Elisa Cancian, et al. "Correlations between Persistent Olfactory and Semantic Memory Disorders after SARS-CoV-2 Infection." Brain Sciences 12, no. 6 (2022): 714. http://dx.doi.org/10.3390/brainsci12060714.

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Background: One of the main symptoms of COVID-19 is hyposmia or even anosmia. Olfactory identification is most often affected. In addition, some cognitive disorders tend to appear following the infection, particularly regarding executive functions, attention, and memory. Olfaction, and especially olfactory identification, is related to semantic memory which manages general knowledge about the world. The main objective of this study was to determine whether semantic memory is impaired in case of persistent post COVID-19 olfactory disorders. Methods: 84 patients (average age of 42.8 ± 13.6 years
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26

Welge-Lussen, Antje, Andrea Hilgenfeld, Thomas Meusel, and Thomas Hummel. "Long-term follow-up of posttraumatic olfactory disorders." Rhinology journal 50, no. 1 (2012): 67–72. http://dx.doi.org/10.4193/rhino11.141.

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Objective: This study aims to determine the long-term recovery rate of posttraumatic olfactory disorders and to evaluate whether a lateralized disorder influences recovery. Method: Olfactory function of 67 patients with posttraumatic olfactory disorders were examined twice using the `Sniffin` Sticks` test battery. Olfactory function was classified based on composite TDI (Threshold, Discrimination and Identification) score. Subjective impairment was rated by visual analogue scale ranging from 0 to 10. Results: First and second examinations were conducted an average of 16.7 months and 74 months
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27

Bezeha, Bohdan. "Our observations regarding olfactory disorders in COVID-19." OTORHINOLARYNGOLOGY, No3-4(5) 2022 (July 29, 2022): 71–76. http://dx.doi.org/10.37219/2528-8253-2022-3-71.

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Topicality: Despite a large number of patients and, accordingly, the large number of publications in the medical literature, numerous clinical manifestations of the disease due to COVID-19 have not yet been sufficiently studied. One of the leading symptoms of COVID-19 is impaired olfactory function, primarily anosmia. According to the literature, anosmia is noted in 30 to 60% of patients. It can be an early and sometimes the only characteristic symptom of the disease. Treatment of olfactory disorders is a difficult task. Therefore timely detection of disorders and early targeted therapy is of
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28

Mun, Sue Jean. "Testing for Olfactory and Gustatory Disorders." Journal of Clinical Otolaryngology Head and Neck Surgery 31, no. 2 (2020): 148–54. http://dx.doi.org/10.35420/jcohns.2020.31.2.148.

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29

Doty, Richard. "The Olfactory System and Its Disorders." Seminars in Neurology 29, no. 01 (2009): 074–81. http://dx.doi.org/10.1055/s-0028-1124025.

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30

Amali, Amin, Amir Arvin Sazgar, Maziar Motiee Langeroudi, and Babak Saedi. "Olfactory Disorders in HIV Positive Patients." Otolaryngology–Head and Neck Surgery 147, no. 2_suppl (2012): P252. http://dx.doi.org/10.1177/0194599812451426a405.

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31

Guekht, A. B., A. I. Kryukov, A. A. Kazakova, R. G. Akzhigitov, N. V. Gulyaeva, and T. A. Druzhkova. "Olfactory disorders as a multidisciplinary problem." Zhurnal nevrologii i psikhiatrii im. S.S. Korsakova 122, no. 12 (2022): 32. http://dx.doi.org/10.17116/jnevro202212212132.

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32

Usova, O. M. "Comparative assessment of the role of TMPRSS2 and ACE-2 receptors in the development of olfactory disorders in infection with coronavirus SARS-CoV-2." Morphologia 18, no. 1 (2024): 78–82. http://dx.doi.org/10.26641/1997-9665.2024.1.78-82.

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Background. Today, evidence of the impact of the SARSCoV-2 coronavirus not only on the cells of the olfactory epithelium, but also on the components of the deeper parts of the olfactory system (olfactory bulbs and the olfactory area of the cerebral cortex), indicates the expression of proteins by the cells of the olfactory epithelium that contribute to further penetration of the virus. An urgent problem is the lack of comprehensive studies of the role of morphological and immunological features of various parts of the olfactory system in the occurrence of olfactory disorders and insufficient u
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33

Simonini, Ludovica, Francesca Frijia, Lamia Ait Ali, et al. "A Comprehensive Review of COVID-19-Related Olfactory Deficiency: Unraveling Associations with Neurocognitive Disorders and Magnetic Resonance Imaging Findings." Diagnostics 14, no. 4 (2024): 359. http://dx.doi.org/10.3390/diagnostics14040359.

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Olfactory dysfunction (OD) is one of the most common symptoms in COVID-19 patients and can impact patients’ lives significantly. The aim of this review was to investigate the multifaceted impact of COVID-19 on the olfactory system and to provide an overview of magnetic resonance (MRI) findings and neurocognitive disorders in patients with COVID-19-related OD. Extensive searches were conducted across PubMed, Scopus, and Google Scholar until 5 December 2023. The included articles were 12 observational studies and 1 case report that assess structural changes in olfactory structures, highlighted t
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34

Pan, Xiaodan, Yuan Zhang, Chengshuo Wang, and Luo Zhang. "Evaluation of nasal symptoms to distinguish eosinophilic from noneosinophilic nasal polyps based on peripheral blood." Allergy and Asthma Proceedings 42, no. 3 (2021): 214–21. http://dx.doi.org/10.2500/aap.2021.42.210004.

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Background: Patients with eosinophilic chronic rhinosinusitis with nasal polyps (eCRSwNP) have poorer outcomes after endoscopic sinus surgery and a higher recurrence rate. Objective: This study aimed to investigate the profile of clinical symptoms of eCRSwNP and the related risk factors. Methods: We prospectively enrolled 298 inpatients with CRSwNP from February 2019 to December 2019. The patients were divided into eCRSwNP and non-eCRSwNP groups based on the percentage of blood eosinophils; the cutoff value was set at 3.05%. Clinical data on questionnaires, visual analog scale (VAS) scores, an
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35

Yu, Yunqing, Ping Liao, and Ruotian Jiang. "Ion Channels in Odor Information Processing of Neural Circuits of the Vertebrate Olfactory Bulb." International Journal of Molecular Sciences 25, no. 24 (2024): 13259. https://doi.org/10.3390/ijms252413259.

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Olfactory disorders and their associated complications present a considerable challenge to an individual’s quality of life and emotional wellbeing. The current range of treatments, including surgical procedures, pharmacological interventions, and behavioral training, frequently proves ineffective in restoring olfactory function. The olfactory bulb (OB) is essential for odor processing and plays a pivotal role in the development of these disorders. Despite the acknowledged significance of ion channels in sensory functions and related pathologies, their specific involvement in OB remains unexplo
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36

Harf Poluan, Fransiskus, and Lina Marlina. "Analysis of the Effect of Life Disorders on Taste Perception." Galore International Journal of Health Sciences and Research 8, no. 4 (2023): 45–54. http://dx.doi.org/10.52403/gijhsr.20230406.

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Smell disorders mostly damage the olfactory membrane of the sense of smell. This can reduce the ability to detect smells, reduce the ability to taste, or food, and even lose appetite. This research aimed to find real evidence of the influence of olfactory disturbances on taste perception carried out on the FK UKI Students’ class of 2012. This research used an experimental design; data was taken in July 2015, and 32 students were used as research subjects. The research examined participants' taste perceptions through an intervention by covering the patient's nose as a symbol of olfactory distur
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37

Suharta, M. Tata. "Symptoms of Depression in Patients with Chemosensory Disorders." Open Access Indonesian Journal of Medical Reviews 1, no. 1 (2021): 12–15. http://dx.doi.org/10.37275/oaijmr.v1i1.549.

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Chemosenses are frequently reported in patients with chemosensory impairment. The present investigation intends to clarify whether there are differential pacts on symptoms of depression between the types (smell dysfunction, taste dysfunction, and combination smell and taste dysfunction), severe- ity, length or source of dysfunction. At the same time, diminished olfaction input and taste appear to have a detrimental influence on emotional dysfunction aggravation. In patients with mixed olfactory or gustatory dysfunction in clinical practice, early management should be considered for depressure
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38

Ozdemir, Nuriye Guzin, Ibrahim Burak Atci, Sevda Bag, Hakan Yilmaz, Yesim Karagoz, and Adem Yilmaz. "Magnetic resonance imaging study; does the olfactory bulb volume change in major depression?" Romanian Neurosurgery 30, no. 1 (2016): 98–103. http://dx.doi.org/10.1515/romneu-2016-0015.

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Abstract Goal: The olfactory region function disorders and olfactory bulb volume changes in neurodegenerative and neuropsychiatric disorders are defined. In this study, the olfactory bulb values of patients diagnosed with major depression in accordance with DMS-IV criteria, are measured with MRI, and these values are compared with the values of healthy volunteers to see if there are any statistically significant changes. Method: The study was carried out with 20 healthy volunteers and 20 patients who had been diagnosed with acute major depression in accordance with ‘diagnostic and statistical
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39

Araújo, Laura, Vanessa Arata, and Ricardo G. Figueiredo. "Olfactory Disorders in Post-Acute COVID-19 Syndrome." Sinusitis 5, no. 2 (2021): 116–22. http://dx.doi.org/10.3390/sinusitis5020012.

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Altered smell is one of the most prevalent symptoms in acute COVID-19 infection. Although most patients recover normal neurosensory function in a few weeks, approximately one-tenth of patients report long-term smell dysfunction, including anosmia, hyposmia, parosmia and phantosmia, with a particularly notable impact on quality of life. In this complex scenario, inflammation and cellular damage may play a key role in the pathogenesis of olfactory dysfunctions and may affect olfactory signaling from the peripheral to the central nervous system. Appropriate management of smell disturbances in COV
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40

Rapiejko, Piotr. "Sense of smell disorders in family physician practice." Alergoprofil 17, no. 2 (2021): 47–53. http://dx.doi.org/10.24292/01.ap.172260521.

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A properly functioning sense of smell recognizes both food and danger and provides sensory input. Sense of smell is lost and/or impaired in diseases accompanied by impaired nasal patency such as chronic rhinosinusitis with or without nasal polyps, allergic rhinitis, respiratory infections including acute rhinosinusitis. In the case of rhinosinusitis in adults, olfactory impairment is one of the four main symptoms of the disease. They can also be caused by damage to the olfactory neuron, e.g. in the course of a viral infection. Loss of smell and/or taste reported by patients with COVID-19 may b
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41

Qiu, Chenghao, Chong Cui, Charlotte Hautefort, et al. "Olfactory and Gustatory Dysfunction as an Early Identifier of COVID-19 in Adults and Children: An International Multicenter Study." Otolaryngology–Head and Neck Surgery 163, no. 4 (2020): 714–21. http://dx.doi.org/10.1177/0194599820934376.

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Objective To evaluate the prevalence and characteristics of olfactory or gustatory dysfunction in coronavirus disease 2019 (COVID-19) patients. Study Design Multicenter case series. Setting Five tertiary care hospitals (3 in China, 1 in France, 1 in Germany). Subjects and Methods In total, 394 polymerase chain reaction (PCR)–confirmed COVID-19-positive patients were screened, and those with olfactory or gustatory dysfunction were included. Data including demographics, COVID-19 severity, patient outcome, and the incidence and degree of olfactory and/or gustatory dysfunction were collected and a
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42

Zhang, Jingjing, Zixuan Zhao, Siqi Sun, et al. "Olfactory Evaluation in Alzheimer’s Disease Model Mice." Brain Sciences 12, no. 5 (2022): 607. http://dx.doi.org/10.3390/brainsci12050607.

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Olfactory dysfunction is considered a pre-cognitive biomarker of Alzheimer’s disease (AD). Because the olfactory system is highly conserved across species, mouse models corresponding to various AD etiologies have been bred and used in numerous studies on olfactory disorders. The olfactory behavior test is a method required for early olfactory dysfunction detection in AD model mice. Here, we review the olfactory evaluation of AD model mice, focusing on traditional olfactory detection methods, olfactory behavior involving the olfactory cortex, and the results of olfactory behavior in AD model mi
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43

Adamova, A. S., E. G. Klocheva, and V. V. Goldobin. "Variants of persistent olfactory dysfunction associated with Novel Coronavirus infection and treatment results." Medical alphabet, no. 21 (November 8, 2024): 57–62. http://dx.doi.org/10.33667/2078-5631-2024-21-57-62.

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The problem of the occurrence of persistent olfactory dysfunction (OD) associated with Novel Coronavirus infection (COVID-19) has now become relevant, however, a regulated standard of therapy has not been developed. According to the literature, about 60 % of patients report the presence of olfactory disorders that persist for several months or more after recovery from COVID-19. However, no more than 5 % seek medical help for olfactory disorders, which indicates the importance of the problem and the need for treatment in a polyclinic setting. Currently, two main areas of treatment for quantitat
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44

Vladimirova, T. Yu, A. M. Popova, and M. N. Popov. "The use of intranasal glucocorticosteroids in the treatment of persistent allergic rhinitis after COVID-19 infection." Meditsinskiy sovet = Medical Council, no. 8 (May 17, 2022): 106–10. http://dx.doi.org/10.21518/2079-701x-2022-16-8-106-110.

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Introduction. Modern algorithms for the diagnosis and treatment of allergic rhinitis (AR) recommend a stepwise approach for managing symptoms of the disease. A part of patients with AR have symptoms that indicate to the past COVID-19 followed by significant impairment of the olfactory function. The article places special emphasis on the intranasal glucocorticosteroid option of treatment to manage nasal and general symptoms in persistent AR.The aim of the study is to evaluate the efficacy of mometasone furoate in patients with a confirmed diagnosis of persistent AR, olfactory disorders, and pas
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45

Kazour, François, Sami Richa, Chantale Abi Char, Boriana Atanasova, and Wissam El-Hage. "Olfactory Memory in Depression: State and Trait Differences between Bipolar and Unipolar Disorders." Brain Sciences 10, no. 3 (2020): 189. http://dx.doi.org/10.3390/brainsci10030189.

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Background: Changes in olfactory recognition memory may constitute sensory markers in depression. Significant differences may exist between unipolar and bipolar depression. Our study compares olfactory memory between control, unipolar, and bipolar patients in depressed and euthymic states in order to identify potential markers of depression. Methods: 176 participants were recruited in 5 groups: depressed bipolar (DB), euthymic bipolar (EB), depressed unipolar (DU), euthymic unipolar (EU), and controls (HC). The participants had a standardized clinical and olfactory assessment (olfactory memory
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46

Scangas, George A., and Benjamin S. Bleier. "Anosmia: Differential Diagnosis, Evaluation, and Management." American Journal of Rhinology & Allergy 31, no. 1 (2017): e3-e7. http://dx.doi.org/10.2500/ajra.2017.31.4403.

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The ability to scrutinize our surroundings remains heavily dependent on the sense of smell. From the ability to detect dangerous situations such as fires to the recollection of a fond memory triggered by an odor, the advantages of an intact olfactory system cannot be overstated. Outcomes studies have highlighted the profound negative impact of anosmia and parosmia on the overall quality of life. The National Institute on Deafness and Other Communication Disorders estimates that ∼1.4% of the United States population experiences chronic olfactory dysfunction and smell loss. Efforts have focused
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47

Doležal, Pavel, E. Račeková, Marcela Martončíková, et al. "Results of treatment of olfactory disorders after COVID-19 disease using olfactory training." Otorinolaryngologie a foniatrie 71, no. 3 (2022): 147–55. http://dx.doi.org/10.48095/ccorl2022147.

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Objective: The aim of this study is to fi nd out how many patients with an ongoing smell and taste disorder after COVID-19 infection, can improve the subjective perception of smell by olfactory training method. Methods: Patients after COVID-19 (fi rst and second wave of the pandemic in 2020 and 2021) with persisting smell disorder (hyposmia, anosmia, parosmia, fantosmia) with or without taste disorder and while the olfactory disorder did not improve within one month afterrecovery, signed up on the website www.cuch.sk and asked for a testing set (perfumed felt-tip pens) to be sent. After a self
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48

Avrunin, Oleg, Yana Nosova, Sergii Zlepko, Ibrahim Younouss Abdelhamid, and Nataliia Shushliapina. "ASSESSMENT OF THE DIAGNOSTIC VALUE OF THE METHOD OF COMPUTER OLFACTOMETRY." Informatyka, Automatyka, Pomiary w Gospodarce i Ochronie Środowiska 9, no. 3 (2019): 18–21. http://dx.doi.org/10.35784/iapgos.236.

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Olfactory studies can be a criterion for evaluating rhinosurgical intervention, and olfactory impairment may indicate respiratory impairment. Therefore, the urgent task is to develop an integrated approach to determining respiratory and olfactory disorders. A structural scheme was developed for the method of objective diagnosis of respiratory and olfactory disorders, taking into account the measu, rement of both the aerodynamic parameters of nasal breathing and the calculation of energy characteristics, which are used to determine olfactory sensitivity. The diagnostic significance of the propo
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49

Beloglazov, V. A., E. V. Burtseva, I. A. Yatskov, K. V. Bubley, A. S. Novosad, and N. A. Shadchneva. "Using essential oils in rehabilitation of olfactory disorders in patients who have had a new coronavirus infection." Acta Biomedica Scientifica 9, no. 5 (2024): 107–13. http://dx.doi.org/10.29413/abs.2024-9.5.11.

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Background. SARS-CoV-2 infection often results in olfactory disorder at different levels of the nervous system, which may persist as anosmia, parosmia, hyperosmia, hyposmia, cacosmia, and olfactory hallucinations after recovery.The aim. To study the effect of essential oils on the restoration of the olfactory apparatus in patients with coronavirus.Materials and methods. We examined 138 people (mean age 19.9 ± 7.05 years) with olfactory complaints, 60 of them underwent olfactory training with essential oils (EO) for 2 months. Olfactory function was assessed using the Hansen – Roseburg method be
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Arpaia, Pasquale, Andrea Cataldo, Sabatina Criscuolo, Egidio De Benedetto, Antonio Masciullo, and Raissa Schiavoni. "Assessment and Scientific Progresses in the Analysis of Olfactory Evoked Potentials." Bioengineering 9, no. 6 (2022): 252. http://dx.doi.org/10.3390/bioengineering9060252.

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The human sense of smell is important for many vital functions, but with the current state of the art, there is a lack of objective and non-invasive methods for smell disorder diagnostics. In recent years, increasing attention is being paid to olfactory event-related potentials (OERPs) of the brain, as a viable tool for the objective assessment of olfactory dysfunctions. The aim of this review is to describe the main features of OERPs signals, the most widely used recording and processing techniques, and the scientific progress and relevance in the use of OERPs in many important application fi
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