Academic literature on the topic 'Oligodeoxyribonucleotides'

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Journal articles on the topic "Oligodeoxyribonucleotides"

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Arnold, Luboš, Zdeněk Točík, Eliška Bradková, Zdeněk Hostomský, Václav Pačes, and Jiří Smrt. "Automated chloridite and amidite synthesis of oligodeoxyribonucleotides on a long chain support using amidine protected purine nucleosides." Collection of Czechoslovak Chemical Communications 54, no. 2 (1989): 523–32. http://dx.doi.org/10.1135/cccc19890523.

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Preparation of solid supports with long aliphatic spacer for the oligonucleotide synthesis is described. Automated synthesis of oligodeoxyribonucleotides using in situ prepared methylchlorophosphite intermediates from amidine protected purine nucleosides is described. Phosphoramidite synthesis of oligodeoxyribonucleotides mediated by 1-methylimidazole trifluoromethanesulfonate is described. Novel isolation of crude oligonucleotides by ethanol precipitation of potassium salts is described.
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Karpyshev, Nikolay N. "Phosphite Synthesis of Oligodeoxyribonucleotides." Russian Chemical Reviews 57, no. 9 (September 30, 1988): 886–96. http://dx.doi.org/10.1070/rc1988v057n09abeh003398.

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Jonathan Rudolph, M., Michael S. Reitman, Eric W. MacMillan, and Alan F. Cook. "PHOSPHONOACETATE DERIVATIVES OF OLIGODEOXYRIBONUCLEOTIDES." Nucleosides and Nucleotides 15, no. 11-12 (November 1996): 1725–39. http://dx.doi.org/10.1080/07328319608002728.

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Stengele, Klaus-Peter, and Wolfgang Pfleiderer. "Improved synthesis of oligodeoxyribonucleotides." Tetrahedron Letters 31, no. 18 (January 1990): 2549–52. http://dx.doi.org/10.1016/0040-4039(90)80122-3.

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&NA;. "Oligodeoxyribonucleotides to treat cancer, arthritis?" Inpharma Weekly &NA;, no. 1069 (January 1997): 14. http://dx.doi.org/10.2165/00128413-199710690-00017.

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CHRISEY, LINDA A., STEPHEN E. WALZ, MEHRAN PAZIRANDEH, and JAMES R. CAMPBELL. "Internalization of Oligodeoxyribonucleotides byVibrio parahaemolyticus." Antisense Research and Development 3, no. 4 (January 1993): 367–81. http://dx.doi.org/10.1089/ard.1993.3.367.

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MAKINO, Keisuke, Hiroaki OZAKI, Tetsufumi MATSUMOTO, Tamio TAKEUCHI, Toshikazu FUKUI, and Hiroyuki HATANO. "Ion-pair chromatography of oligodeoxyribonucleotides." NIPPON KAGAKU KAISHI, no. 7 (1986): 1043–45. http://dx.doi.org/10.1246/nikkashi.1986.1043.

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Hübner, Philipp, Shigeru Iida, and Werner Arber. "Random mutagenesis using degenerate oligodeoxyribonucleotides." Gene 73, no. 2 (December 1988): 319–25. http://dx.doi.org/10.1016/0378-1119(88)90496-9.

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Rotaru, Alexandru, János Kovács, and Andriy Mokhir. "Red light-activated phosphorothioate oligodeoxyribonucleotides." Bioorganic & Medicinal Chemistry Letters 18, no. 15 (August 2008): 4336–38. http://dx.doi.org/10.1016/j.bmcl.2008.06.079.

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KAPLAN, B. "The automated synthesis of oligodeoxyribonucleotides." Trends in Biotechnology 3, no. 10 (October 1985): 253–56. http://dx.doi.org/10.1016/0167-7799(85)90024-1.

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Dissertations / Theses on the topic "Oligodeoxyribonucleotides"

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Wahl, Franck Olivier. "Synthesis and purification of oligodeoxyribonucleotides." Thesis, University of Edinburgh, 1993. http://hdl.handle.net/1842/14625.

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A new highly hydrophobic 5'-hydroxyl protecting group (Tbf-DMTr) has been designed for the purification of synthetic oligonucleotides. Tbf-DMTr-oligonucleotides are strongly retained on RP-HPLC allowing a facile separation from truncated sequences. Subsequently the group can be removed in acidic conditions. The fluorescent properties of TBf-DMTr enable easy detection. The synthesis and purification of long oligonucleotides (> 100-mer) has been undertaken. Additionally a new fluorescent label for oligonucleotides has been developed which enables detection of DNA probes to concentration down to 10-10 mol/l.
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Bonfils, Edwige. "Nouveaux agents antiviraux : oligodeoxyribonucleotides lies a des transporteurs glycosyles." Orléans, 1991. http://www.theses.fr/1991ORLE2013.

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Dans le but de cibler des oligonucleotides antisens diriges contre des genes du virus de l'immunodeficience humaine (vih) vers les monocytes et les macrophages, nous avons realise des conjugues oligonucleotide-serum albumine mannosylee (man-bsa) ou 6-phosphomannosylee (m6p-bsa) specifiquement reconnus et endocytes par les lectines de ces cellules. Des oligomeres resistants (alpha t#1#2) vis-a-vis des degradations enzymatiques et des oligonucleotides 19 meres beta d(#5aagctttatgaggcttaa#3) antisens complementaires de la region (+64, +63) des ltrs du vih ont ete realises. Ces sequences ont du etre modifiees sur l'extremite 3 par une fonction thiol, permettant leur attachement sur les transporteurs glycosyles, et marquees en position 5 par la fluoresceine ou la tyramine radioiodee. Differents conjugues oligonucleotide-neoglycoproteine (man-sab et m6p-sab) ont ete obtenus par couplage via un pont disulfure de ces oligomeres sur les proteines. D'autre part, des oligomeres portant un residu biotine en position 3 ont ete prepares et complexes avec la streptavidine mannosylee. L'etude de l'internalisation des oligonucleotides libres ou conjugues a ete realisee en cytometrie en flux, microscopie confocale et fractionnement cellulaire. Les resultats montrent que les oligomeres transportes par la man-sab, la m6p-sab ou le streptavidine mannosylee sont reconnus par les lectines membranaires de cellules du type macrophage et internalises selon un processus d'endocytose mediee par ces recepteurs. Le ciblage des oligonucleotides par les transporteurs glycosyles permet d'augmenter d'un facteur 10 a 20 la quantite d'oligonucleotide internalisee par les cellules et conduit a une concentration intracellulaire en oligomere 5 a 6 fois superieure a celle du milieu exterieur. Des experiences de pharmacocinetique sur la souris montrent que les transporteurs mannosyles ou 6-phosphomannosyles assurent le transport des oligonucleotides preferentiellement vers le foie, la rate et les poumons qui sont des organes riches en macrophages
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Payne, Andrew Nicholas. "Synthesis of novel fluorocarbocyclic nucleosides and their intercorporation into oligodeoxyribonucleotides." Thesis, University of Exeter, 1991. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.293998.

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Senthong, Pattama. "Repair of oligodeoxyribonucleotides containing O6-alkylguanine by MGMT variant proteins." Thesis, University of Manchester, 2013. https://www.research.manchester.ac.uk/portal/en/theses/repair-of-oligodeoxyribonucleotides-containing-o6alkylguanine-by-mgmt-variant-proteins(a9b2c412-e6ee-4cf1-a862-e4bdbdc9c6c2).html.

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Alkylating agents are a diverse family of compounds whose toxic, mutagenic and carcinogenic effects in living organisms are due to their ability to damage DNA. Humans are exposed to these agents through lifestyle, diet, occupation and some forms of chemotherapy, but they are also formed endogenously. To protect against these adverse effects, a variety of DNA repair process have evolved. Among these is O6-methylguanine-DNA methyltransferase (MGMT), a damage reversal protein that repairs O6-alkylguanine (O6-alkG) adducts by capturing the alkyl group onto a cysteine residue within the protein in an autoinactivating mechanism. Human MGMT is known to be present in at least 12 polymorphic variant forms and numerous studies have partially characterised one or a few of these in relation to cancer susceptibility. The main objective in this thesis was to compare the substrate specificity of seven MGMT variant proteins, and also a putative size-variant of the normal MGMT, using short ODNs containing 12 different O6-alkylguanines (O6-alkGs). A variety of analytical methods was used in these studies, including radioisotope-based assays, enzyme-linked immunosorbent assays (ELISA), mass spectrometry (MS) and surface plasmon resonance (SPR). The most potent inactivators of all MGMTs were ODNs containing O6-BzG followed by O6-MeG and O6-CMG. For the other ODNs, the MGMT proteins could be classed in three groups: firstly Wt, and the F84, V143/R178 and F84/V143/R178 variants for which the potencies were O6-PrG > O6-PobG > O6-EtG; secondly R160 and F84/R160 for which O6-PrG > O6-EtG > O6- PobG and finally Q128 for which O6- PobG > O6-PrG > O6-EtG. Alkyl group transfer from six of the ODNs to the active site cysteine of Wt MGMT was demonstrated by MS. The Q128 variant was the most resistant to inactivation by all modified ODNs. The R160 and F84/R160 variants were more resistant than the other variants to inactivation by the O6-CMG and O6-PobG containing ODNs. It was also shown that ZnCl2 supplementation during Wt MGMT expression in E.coli significantly increased MGMT specific activity and decreased sensitivity to inactivation by the ODNs. In addition both 5-methylcytosine adjacent and opposite O6-MeG significantly affected the inactivation of Wt MGMT. Finally, it was confirmed that O6-CMG is, contrary to previous reports, a substrate for MGMT, and the inefficient repair of O6-CMG by the E.coli Ogt alkyltransferase protein was shown to be the basis of the error. Studies with human cells suggest that MGMT also repairs O6-CMG in vivo. The results suggest that MGMT variants repair different O6-alkGs at different rates and hence the consequence of alkylating agents exposure will depend not only on the nature of the exposure but also an individual’s own specific MGMT variant.
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Tona, Rolf. "Bioconjugation and cross-linkage of diene-modified oligodeoxyribonucleotides via the Diels-Alder reaction /." [S.l.] : [s.n.], 2004. http://www.zb.unibe.ch/download/eldiss/04tona_r.pdf.

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Kaminski, John J. III. "Suppressive Oligodeoxynucleotides Inhibit Cytosolic DNA Sensing Pathways: A Dissertation." eScholarship@UMMS, 2004. http://escholarship.umassmed.edu/gsbs_diss/669.

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The innate immune system provides an essential first line of defense against infection. Innate immune cells detect pathogens through several classes of Pattern Recognition Receptors (PRR) allowing rapid response to a broad spectrum of infectious agents. Activated receptors initiate signaling cascades that lead to the production of cytokines, chemokines and type I interferons all of which are vital for controlling pathogen load and coordinating the adaptive immune response. Detection of nucleic acids by the innate immune system has emerged as a mechanism by which infection is recognized. Recognition of DNA is complex, influenced by sequence, structure, covalent modification and subcellular localization. Interestingly certain synthetic oligodeoxynucleotides comprised of the TTAGGG motif inhibit proinflammatory responses in a variety of disease models. These suppressive oligodeoxynucleotides (sup ODN) have been shown to directly block TLR9 signaling as well as prevent STAT1 and STAT4 phosphorylation. Recently AIM2 has been shown to engage ASC and assemble an inflammasome complex leading to the caspase-1-dependent maturation of IL-1β and IL-18. The AIM2 inflammasome is activated in response to cytosolic dsDNA and plays an important role in controlling replication of murine cytomegalovirus (MCMV). In the second chapter of this thesis, a novel role for the sup ODN A151 in inhibiting cytosolic nucleic acid sensing pathways is described. Treatment of dendritic cells and macrophages with the A151 abrogated type I IFN, TNF-α and ISG induction in response to cytosolic dsDNA. A151 also reduced INF-β and TNF-α induction in BMDC and BMDM responding to the herpesviruses HSV-1 and MCMV but had no effect on the responses to LPS or Sendai virus. In addition, A151 abrogated caspase-1-dependent IL-1β and IL-18 maturation in dendritic cells stimulated with dsDNA and MCMV. Although inhibition of interferon-inducing pathways and inflammasome assembly was dependent on backbone composition, sequence differentially affected these pathways. While A151 more potently suppressed the AIM2 inflammasome, a related construct C151, proved to be a more potent inhibitor of interferon induction. A151 suppressed inflammasome signaling by binding to AIM2 and competing with immune-stimulatory DNA. The interaction of A151 and AIM2 prevented recruitment of the adapter ASC and assembly of the macromolecular inflammasome complex. Collectively, these findings reveal a new route by which suppressive ODNs modulate the immune system and unveil novel applications for suppressive ODNs in the treatment of infectious and autoimmune diseases. The innate immune response to HSV-1 infection is critical for controlling early viral replication and coordinating the adaptive immune response. The cytokines IL-1β and IL-18 are important effector molecules in the innate response to HSV-1 in vivo. However, the PRRs responsible for the production and maturation of these cytokines have not been fully defined. In the third chapter of this thesis, The TLR2-MyD88 pathway is shown to be essential for the induction of pro-IL-1β transcription in dendritic cells and macrophages responding to HSV-1. The HSV-1 immediate-early protein ICP0 has previously been shown to block TLR2 responses and in keeping with this finding, ICP0 blocked pro-IL-1β expression. Following translation, pro-IL-1β exists as an inactive precursor that must be proteolytically cleaved by a multiprotein complex known as the inflammasome to yield its active form. Inflammasomes are composed of cytoplasmic receptors such as NLRP3 or AIM2, the adapter molecule ASC, and pro-caspase-1. In the present study we found that the NLRP3 inflammasome is important for maturation of IL-1β in macrophages and dendritic cells responding to HSV-1. In contrast the related NLRP12 protein controls IL-1β production in neutrophils. These data indicate that sensing of HSV-1 by TLR2 drives pro-IL-1β transcription and infection activates the inflammasome to mature this cytokine. Moreover, these studies reveal cell type-specific roles for NLRP3 and NLRP12 in inflammasome assembly.
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Kaminski, John J. III. "Suppressive Oligodeoxynucleotides Inhibit Cytosolic DNA Sensing Pathways: A Dissertation." eScholarship@UMMS, 2013. https://escholarship.umassmed.edu/gsbs_diss/669.

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The innate immune system provides an essential first line of defense against infection. Innate immune cells detect pathogens through several classes of Pattern Recognition Receptors (PRR) allowing rapid response to a broad spectrum of infectious agents. Activated receptors initiate signaling cascades that lead to the production of cytokines, chemokines and type I interferons all of which are vital for controlling pathogen load and coordinating the adaptive immune response. Detection of nucleic acids by the innate immune system has emerged as a mechanism by which infection is recognized. Recognition of DNA is complex, influenced by sequence, structure, covalent modification and subcellular localization. Interestingly certain synthetic oligodeoxynucleotides comprised of the TTAGGG motif inhibit proinflammatory responses in a variety of disease models. These suppressive oligodeoxynucleotides (sup ODN) have been shown to directly block TLR9 signaling as well as prevent STAT1 and STAT4 phosphorylation. Recently AIM2 has been shown to engage ASC and assemble an inflammasome complex leading to the caspase-1-dependent maturation of IL-1β and IL-18. The AIM2 inflammasome is activated in response to cytosolic dsDNA and plays an important role in controlling replication of murine cytomegalovirus (MCMV). In the second chapter of this thesis, a novel role for the sup ODN A151 in inhibiting cytosolic nucleic acid sensing pathways is described. Treatment of dendritic cells and macrophages with the A151 abrogated type I IFN, TNF-α and ISG induction in response to cytosolic dsDNA. A151 also reduced INF-β and TNF-α induction in BMDC and BMDM responding to the herpesviruses HSV-1 and MCMV but had no effect on the responses to LPS or Sendai virus. In addition, A151 abrogated caspase-1-dependent IL-1β and IL-18 maturation in dendritic cells stimulated with dsDNA and MCMV. Although inhibition of interferon-inducing pathways and inflammasome assembly was dependent on backbone composition, sequence differentially affected these pathways. While A151 more potently suppressed the AIM2 inflammasome, a related construct C151, proved to be a more potent inhibitor of interferon induction. A151 suppressed inflammasome signaling by binding to AIM2 and competing with immune-stimulatory DNA. The interaction of A151 and AIM2 prevented recruitment of the adapter ASC and assembly of the macromolecular inflammasome complex. Collectively, these findings reveal a new route by which suppressive ODNs modulate the immune system and unveil novel applications for suppressive ODNs in the treatment of infectious and autoimmune diseases. The innate immune response to HSV-1 infection is critical for controlling early viral replication and coordinating the adaptive immune response. The cytokines IL-1β and IL-18 are important effector molecules in the innate response to HSV-1 in vivo. However, the PRRs responsible for the production and maturation of these cytokines have not been fully defined. In the third chapter of this thesis, The TLR2-MyD88 pathway is shown to be essential for the induction of pro-IL-1β transcription in dendritic cells and macrophages responding to HSV-1. The HSV-1 immediate-early protein ICP0 has previously been shown to block TLR2 responses and in keeping with this finding, ICP0 blocked pro-IL-1β expression. Following translation, pro-IL-1β exists as an inactive precursor that must be proteolytically cleaved by a multiprotein complex known as the inflammasome to yield its active form. Inflammasomes are composed of cytoplasmic receptors such as NLRP3 or AIM2, the adapter molecule ASC, and pro-caspase-1. In the present study we found that the NLRP3 inflammasome is important for maturation of IL-1β in macrophages and dendritic cells responding to HSV-1. In contrast the related NLRP12 protein controls IL-1β production in neutrophils. These data indicate that sensing of HSV-1 by TLR2 drives pro-IL-1β transcription and infection activates the inflammasome to mature this cytokine. Moreover, these studies reveal cell type-specific roles for NLRP3 and NLRP12 in inflammasome assembly.
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Claus, Carol L. "Inhibition of troponin C expression in C¦2C¦12 mouse skeletal muscle cells by an antisense oligodeoxyribonucleotide." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2000. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape2/PQDD_0021/MQ47318.pdf.

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Melo, Cristiane Casonato. "Nanopartículas de quitosana como veículo para entrega de oligodeoxiribonucleotídeos antisense." Universidade de São Paulo, 2018. http://www.teses.usp.br/teses/disponiveis/76/76132/tde-17092018-103515/.

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Em 1978, o trabalho realizado por Stephenson e Zamecnik demonstrou a capacidade de um oligonucleotídeo de impedir a expressão de uma proteína específica. Atualmente, duas tecnologias são mais utilizadas para este propósito: os oligodeoxiribonucleotídeos antisense e o RNA de interferência (siRNA), que se aproveitam da capacidade de anelação entre as fitas complementares. A maior diferença entre as duas técnicas é a maquinaria proteica recrutada, isso é, o complexo RISC atua no funcionamento do siRNA, e a protease RNase H atua na clivagem da fita de RNA quando hibridizada com DNA. Apesar da grande aplicabilidade destas tecnologias, tanto para doenças metabólicas quanto para canceres, o veículo de entrega e proteção dessas sequências é de fundamental importância, visto que a aplicação desses oligonucleotídeos livres está sujeita à rápida degradação e ineficiência. A modificação das bases é uma das estratégias para conferir maior estabilidade às sequências, porém estas tem sido relacionadas a um aumento da toxicidade. Nessa dissertação, a quitosana, um polissacarídeo catiônico é utilizado para síntese de nanopartículas e encapsulamento dos oligodeoxiribonucleotídeos antisense (ASO). Para isso, foram realizadas modificações na quitosana comercial como despolimerização, trimetilação ou conjugação com PEG, seguida da síntese das nanopartículas com a adição de tripolifosfato de sódio (TPP) pelo método de gelatinização ionotrópica. A estabilidade das nanopartículas foi medida em função do tempo, da variação de temperatura e da diferença de pH. Além disso, a toxicidade dessas nanopartículas foi analisada através da viabilidade celular em diferentes linhagens, NB-4, HepaRG, HTC e BHK-570. A expressão da proteína verde fluorescente (GFP) na célula NB-4 foi utilizada para avaliar a entrega do ASO desenhado, sendo sua fluorescência monitorada por microscopia confocal. Os resultados demonstram que as nanopartículas se mantiveram estáveis durante o período de tempo analisado, assim como com a temperatura variando de 22 a 45°C e em pH ácido. Cada linhagem celular respondeu de forma diferente ao tratamento com as nanopartículas sem ASO, sendo a linhagem saudável BHK-570 com a maior resistência. Ademais, todas as células apresentaram viabilidade reduzida quando tratadas com concentrações na ordem de 1011 nanopartículas/mL a base de quitosana trimetilada. A fluorescência das células NB-4 quando tratada com as nanopartículas com ASO diminuiu consideravelmente nas 18 primeiras horas, seguida de um aumento após 42 horas. Dessa forma, pode-se concluir que as nanopartículas de quitosana propostas nessa dissertação apresentaram uma excelente alternativa para a entrega de material genético, principalmente para o trato gastro-intestinal, devido à sua estabilidade em pH ácido.
The property of an oligonucleotide to interfere in the expression of a protein was observed in 1978 by Stephenson and Zamecnik. To perform such interference, there are today, two main techniques being explored: antisense oligodeoxyribonucleotides and interference RNA. In both cases, the particularity of their chemical structure is taken into account as soon as they can bind in a complementary manner to the messenger RNA and inhibit its translation. The great difference between these techniques is related to the proteases involved in the process, while for interference RNA the RISC machinery acts, for antisense oligodeoxyribonucleotides RNase H cleaves the RNA in the duplex DNA-RNA. Although these tools to edit the translation process are relevant to the treatment and even cure of metabolic disorders and cancers, it is still not effective when employed without a coating to protect the sequences before it reaches the destiny in vivo. Efforts have been made in developing modified bases to be more stable, but they show some toxicity. In this dissertation, chitosan, a natural cationic polyssacharide, is used to produce nanoparticles to protect the antisense oligodeoxyribonucleotide (ASO). For this reason, the commercial chitosan was modified, depolymerized, trimetilated or PEGlated and the nanoparticles were synthesized with sodium tripolyphosphate (TPP) by ionotropic gelation method. The stability along time, in different pHs and temperatures was assessed. The toxicity of nanoparticles without ASO was quantified by MTT tests in NB-4, HepaRG, HTC and BHK-570 cell lines. A green fluorescent protein (GFP) expressed by NB-4 cells was the target to evaluate the delivery efficiency of the ASO, and its fluorescence was measured by confocal microscopy. Results showed that nanoparticles were stable over time as well as in temperatures ranging from 22 to 45°C and in acidic pH. Each cell line responded in a different manner to the treatment, with the health cell BHK-570 showing higher resistance. Furthermore, all of them presented lower viability when treated with trimetilated chitosan nanoparticles in the highest concentrations (ca 1011 nanoparticles/mL). NB-4 cells presented a decrease in fluorescence in 18 hours of treatment followed by an increase after 42 hours. We conclude that chitosan nanoparticles are a good alternative to the delivery of genetic material even more in the gastro intestinal tract due to its great stability in acid pH values.
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Hartmann, Brigitte. "Contribution a l'etude du polymorphisme et de la structure dynamique de l'adn-z." Orléans, 1987. http://www.theses.fr/1987ORLE2038.

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La conformation des oligonucleotides (m**(5)dc-dg)::(2), (m**(5)dcdg)::(3) et (br**(5)dc-dg)::(3) peut etre sous forme b et z. Les stabilites thermiques de ces 2 formes sont differentes la fusion de la forme b est monophasique, celle de la forme est biphasique. Une premiere transition a ete observe, refletant un remaniement conformationnel intramoleculaire. Ce remaniement intramoleculaire conduit de la forme z a une double helice gauche dont le caractere de nucleotidique de l'unite repetitive est atteint et ou l'empilement des bases est modifie. L'etude du mecanisme d'echange chimique des protons de la guanine montre que dans tous les tampons utilisees catalysent le transfert en accord avec la theorie de biomoted. Etude comparative des cinetiques d'echange des formes z a permis d'attribuer les 2 protons lents aux protons amino de la cytosine
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Book chapters on the topic "Oligodeoxyribonucleotides"

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White, H. A. "Chemical Synthesis of Oligodeoxyribonucleotides." In Techniques in Molecular Biology, 228–50. Boston, MA: Springer US, 1987. http://dx.doi.org/10.1007/978-1-4615-9799-5_13.

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Black, Diane M., and Peter T. Gilham. "Sequence Analysis of Oligodeoxyribonucleotides." In Protocols for Oligonucleotide Conjugates, 265–76. Totowa, NJ: Humana Press, 1994. http://dx.doi.org/10.1007/978-1-59259-513-6_10.

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Singh, Ramendra K., and Shipra Agarwal. "Fluorescent Labeling and Its Effect on Hybridization of Oligodeoxyribonucleotides." In Reviews in Fluorescence 2008, 161–94. New York, NY: Springer New York, 2009. http://dx.doi.org/10.1007/978-1-4419-1260-2_7.

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Inouye, Masayori, Jau-Ren Mao, Tadashi Shimamoto, and Sumiko Inouye. "In vivo Production of Oligodeoxyribonucleotides of Specific Sequences: Application to Antisense DNA." In Novartis Foundation Symposia, 224–34. Chichester, UK: John Wiley & Sons, Ltd., 2007. http://dx.doi.org/10.1002/9780470515396.ch17.

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Yamamoto, S., T. Yamamoto, and T. Tokunaga. "Oligodeoxyribonucleotides with 5′-ACGT-3′ or 5′-TCGA-3′ Sequence Induce Production of Interferons." In Immunobiology of Bacterial CpG-DNA, 23–39. Berlin, Heidelberg: Springer Berlin Heidelberg, 2000. http://dx.doi.org/10.1007/978-3-642-59672-8_2.

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Cooperman, Barry S., Parimi Muralikrishna, and Rebecca W. Alexander. "Photolabile Oligodeoxyribonucleotide Probes of E. coli Ribosome Structure." In The Translational Apparatus, 465–76. Boston, MA: Springer US, 1993. http://dx.doi.org/10.1007/978-1-4615-2407-6_44.

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Otter, Albin, Christopher C. Hanstock, George Kotovych, Bernard Rayner, Jacques J. Vasseur, Jean-Louis Imbach, and J. William Lown. "Molecular Recognition of DNA Binding Agents: High-Field 1H and 3 1P One- and Two-Dimensional NMR Studies on the 1:1 Intercalation Complexes of Mitoxantrone with Selected Oligodeoxyribonucleotides." In Mechanisms of DNA Damage and Repair, 211–18. Boston, MA: Springer US, 1986. http://dx.doi.org/10.1007/978-1-4615-9462-8_22.

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Phillips, L. R., K. A. Gallo, G. Zon, W. J. Stec, and B. Uznanski. "Fast-Atom Bombardment Mass Spectra of O-Isopropyl Oligodeoxyribonucleotide Triesters." In Springer Series in Chemical Physics, 518–20. Berlin, Heidelberg: Springer Berlin Heidelberg, 1986. http://dx.doi.org/10.1007/978-3-642-82724-2_138.

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Lampel, Keith A., James A. Jagow, and Megan L. Troxell. "Oligodeoxyribonucleotide Probe Specific For The 230 Kilobase Pair Virulence Plasmid in Enteroinvasive Escherichia Coli and Shigella." In Microbial Toxins in Foods and Feeds, 119–26. Boston, MA: Springer US, 1990. http://dx.doi.org/10.1007/978-1-4613-0663-4_11.

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Hill, Walter E., David G. Camp, William E. Tapprich, and Anchalee Tassanakajohn. "[26] Probing ribosome structure and function using short oligodeoxyribonucleotides." In Methods in Enzymology, 401–19. Elsevier, 1988. http://dx.doi.org/10.1016/s0076-6879(88)64057-2.

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Conference papers on the topic "Oligodeoxyribonucleotides"

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Rotaru, Alexandru, Janos Kovács, and Andriy Mokhir. "Red light activated phosphothioate oligodeoxyribonucleotides." In XIVth Symposium on Chemistry of Nucleic Acid Components. Prague: Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, 2008. http://dx.doi.org/10.1135/css200810282.

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Guga, Piotr, Anna Maciaszek, and Wojciech J. Stec. "Oxathiaphospholane approach to the synthesis of oligodeoxyribonucleotides containing stereodefined internucleotide phosphoroselenoate function." In XIIIth Symposium on Chemistry of Nucleic Acid Components. Prague: Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, 2005. http://dx.doi.org/10.1135/css200507167.

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Millington, Christopher L., Takayuki Shibata, Geoff Margison, and David M. Williams. "Novel post DNA synthesis chemistry and biological evaluation of O6-alkylguanine-containing oligodeoxyribonucleotides." In XIVth Symposium on Chemistry of Nucleic Acid Components. Prague: Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, 2008. http://dx.doi.org/10.1135/css200810133.

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Ketomäki, Kaisa, and Harri Lönnberg. "Mixed-phase hybridization of short oligodeoxyribonucleotides on microscopic polymer particles: The effects of various one-base mismatches on the duplex stability." In XIIth Symposium on Chemistry of Nucleic Acid Components. Prague: Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, 2002. http://dx.doi.org/10.1135/css200205342.

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Hayakawa, Yoshihiro, Akira Sakakura, Sophie B. Heidenhain, and Masanori Kataoka. "A facile solid-phase synthesis of oligodeoxyribonucleotides and their amino acid conjugates via the allyl-protected phosphoramidite approach with benzimidazolium triflate as a promoter." In XIth Symposium on Chemistry of Nucleic Acid Components. Prague: Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, 1999. http://dx.doi.org/10.1135/css199902105.

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Abdelhady, Rasha A., Perdita E. Barran, David M. Williams, and Andrew C. Povey. "Abstract 4242: Mass spectroscopic analysis of MGMT tryptic peptides allows detection ofO6-alkylguanine adducts in oligodeoxyribonucleotides, temozolomide modified calf thymus DNA and human colorectal cancer DNA." In Proceedings: AACR Annual Meeting 2017; April 1-5, 2017; Washington, DC. American Association for Cancer Research, 2017. http://dx.doi.org/10.1158/1538-7445.am2017-4242.

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De Acha, N., C. Elosua, P. Zubiate, and F. J. Arregui. "P1OS.5 - Luminescent optical fiber Hg2+ sensor based on an oligodeoxyribonucleotide sequence." In 17th International Meeting on Chemical Sensors - IMCS 2018. AMA Service GmbH, Von-Münchhausen-Str. 49, 31515 Wunstorf, Germany, 2018. http://dx.doi.org/10.5162/imcs2018/p1os.5.

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