Academic literature on the topic 'OLIGONUCLEOTIDE FREQUENCIES'

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Journal articles on the topic "OLIGONUCLEOTIDE FREQUENCIES"

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Wang, G., D. D. Levy, M. M. Seidman, and P. M. Glazer. "Targeted mutagenesis in mammalian cells mediated by intracellular triple helix formation." Molecular and Cellular Biology 15, no. 3 (1995): 1759–68. http://dx.doi.org/10.1128/mcb.15.3.1759.

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As an alternative to standard gene transfer techniques for genetic manipulation, we have investigated the use of triple helix-forming oligonucleotides to target mutations to selected genes within mammalian cells. By treating monkey COS cells with oligonucleotides linked to psoralen, we have generated targeted mutations in a simian virus 40 (SV40) vector contained within the cells via intracellular triple helix formation. Oligonucleotide entry into the cells and sequence-specific triplex formation within the SV40 DNA deliver the psoralen to the targeted site. Photoactivation of the psoralen by
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Martindale, Colin, and Andrzej K. Konopka. "Oligonucleotide frequencies in DNA follow a Yule distribution." Computers & Chemistry 20, no. 1 (1996): 35–38. http://dx.doi.org/10.1016/s0097-8485(96)80005-2.

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Hong, Juan. "Prediction of oligonucleotide frequencies based upon dinucleotide frequencies obtained from the nearest neighbor analysis." Nucleic Acids Research 18, no. 6 (1990): 1625–28. http://dx.doi.org/10.1093/nar/18.6.1625.

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Tyagi, Antariksh, Sumit K. Bag, Virendra Shukla, Sribash Roy, and Rakesh Tuli. "Oligonucleotide Frequencies of Barcoding Loci Can Discriminate Species across Kingdoms." PLoS ONE 5, no. 8 (2010): e12330. http://dx.doi.org/10.1371/journal.pone.0012330.

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Goussarov, Gleb, Ilse Cleenwerck, Mohamed Mysara, et al. "PaSiT: a novel approach based on short-oligonucleotide frequencies for efficient bacterial identification and typing." Bioinformatics 36, no. 8 (2020): 2337–44. http://dx.doi.org/10.1093/bioinformatics/btz964.

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Abstract Motivation One of the most widespread methods used in taxonomy studies to distinguish between strains or taxa is the calculation of average nucleotide identity. It requires a computationally expensive alignment step and is therefore not suitable for large-scale comparisons. Short oligonucleotide-based methods do offer a faster alternative but at the expense of accuracy. Here, we aim to address this shortcoming by providing a software that implements a novel method based on short-oligonucleotide frequencies to compute inter-genomic distances. Results Our tetranucleotide and hexanucleot
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McFarland, JG, RH Aster, JB Bussel, JG Gianopoulos, RS Derbes, and PJ Newman. "Prenatal diagnosis of neonatal alloimmune thrombocytopenia using allele- specific oligonucleotide probes." Blood 78, no. 9 (1991): 2276–82. http://dx.doi.org/10.1182/blood.v78.9.2276.2276.

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Abstract The prediction of neonatal alloimmune thrombocytopenia (NATP) in affected families has, in the past, been based on information about gene frequencies of the antigen systems involved, parental phenotyping, and fetal platelet counts. We explored the feasibility of allele- specific oligonucleotide probe typing for PIA antigens to determine the risk of second or subsequent fetuses in families where one infant had a diagnosis of anti-PIA1-mediated NATP. A total of eight families at risk for delivering an affected fetus were studied with both serologic and oligonucleotide typing. The correl
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McFarland, JG, RH Aster, JB Bussel, JG Gianopoulos, RS Derbes, and PJ Newman. "Prenatal diagnosis of neonatal alloimmune thrombocytopenia using allele- specific oligonucleotide probes." Blood 78, no. 9 (1991): 2276–82. http://dx.doi.org/10.1182/blood.v78.9.2276.bloodjournal7892276.

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The prediction of neonatal alloimmune thrombocytopenia (NATP) in affected families has, in the past, been based on information about gene frequencies of the antigen systems involved, parental phenotyping, and fetal platelet counts. We explored the feasibility of allele- specific oligonucleotide probe typing for PIA antigens to determine the risk of second or subsequent fetuses in families where one infant had a diagnosis of anti-PIA1-mediated NATP. A total of eight families at risk for delivering an affected fetus were studied with both serologic and oligonucleotide typing. The correlation bet
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Obata, Fumiya, Koichi Ito, Takehisa Kaneko, et al. "HLA-DR gene frequencies in the Japanese population obtained by oligonucleotide genotyping." Tissue Antigens 38, no. 1 (1991): 124–32. http://dx.doi.org/10.1111/j.1399-0039.1991.tb02025.x.

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Bai, Yu, Yuki Iwasaki, Shigehiko Kanaya, Yue Zhao, and Toshimichi Ikemura. "A Novel Bioinformatics Method for Efficient Knowledge Discovery by BLSOM from Big Genomic Sequence Data." BioMed Research International 2014 (2014): 1–11. http://dx.doi.org/10.1155/2014/765648.

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With remarkable increase of genomic sequence data of a wide range of species, novel tools are needed for comprehensive analyses of the big sequence data. Self-Organizing Map (SOM) is an effective tool for clustering and visualizing high-dimensional data such as oligonucleotide composition on one map. By modifying the conventional SOM, we have previously developed Batch-Learning SOM (BLSOM), which allows classification of sequence fragments according to species, solely depending on the oligonucleotide composition. In the present study, we introduce the oligonucleotide BLSOM used for characteriz
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Abe, Takashi, Yuta Hamano, and Toshimichi Ikemura. "Visualization of Genome Signatures of Eukaryote Genomes by Batch-Learning Self-Organizing Map with a Special Emphasis onDrosophilaGenomes." BioMed Research International 2014 (2014): 1–8. http://dx.doi.org/10.1155/2014/985706.

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A strategy of evolutionary studies that can compare vast numbers of genome sequences is becoming increasingly important with the remarkable progress of high-throughput DNA sequencing methods. We previously established a sequence alignment-free clustering method “BLSOM” for di-, tri-, and tetranucleotide compositions in genome sequences, which can characterize sequence characteristics (genome signatures) of a wide range of species. In the present study, we generated BLSOMs for tetra- and pentanucleotide compositions in approximately one million sequence fragments derived from 101 eukaryotes, fo
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Dissertations / Theses on the topic "OLIGONUCLEOTIDE FREQUENCIES"

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PRATIBHA. "DISCRIMINATION OF PATHOGENIC SPECIES USING OLIGONUCLEOTIDE FREQUENCIES OF BARCODING." Thesis, 2016. http://dspace.dtu.ac.in:8080/jspui/handle/repository/14707.

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Now days, molecular taxonomy has become a more targeted tool to classify enormous diversity of the organisms present on earth. As a part of molecular taxonomy DNA based methods especially DNA bar coding serves as a more precise tool for identification and subsequent targeted techniques. The genuses of worms which are chosen are the popular organisms of various human and animal diseases. Currently, only physiological mode of diagnoses is available to detect the type of infection. Our proposed technique works on knowledge based methods of diagnosis where the basis of diagnosis is taken as
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Book chapters on the topic "OLIGONUCLEOTIDE FREQUENCIES"

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Wang, Jia, Chuang Ma, Dao Zhou, Libin Zhang, and Yanhong Zhou. "Accurately Predicting Transcription Start Sites Using Logitlinear Model and Local Oligonucleotide Frequencies." In Bio-Inspired Computing and Applications. Springer Berlin Heidelberg, 2012. http://dx.doi.org/10.1007/978-3-642-24553-4_16.

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Conference papers on the topic "OLIGONUCLEOTIDE FREQUENCIES"

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Wu, Hongwei. "PCA-based linear combinations of oligonucleotide frequencies for metagenomic DNA fragment binning." In 2008 IEEE Symposium on Computational Intelligence in Bioinformatics and Computational Biology (CIBCB 2008). IEEE, 2008. http://dx.doi.org/10.1109/cibcb.2008.4675758.

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