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1

Brenes-Álvarez, Mercedes, Pedro García-García, Eva María Ramírez, Eduardo Medina, Manuel Brenes, and Concepción Romero. "Potassium Hydroxide Extraction of Polyphenols from Olive Leaves: Effect on Color and Acrylamide Formation in Black Ripe Olives." Foods 13, no. 19 (2024): 3180. http://dx.doi.org/10.3390/foods13193180.

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Olive leaves are generated in large quantities in olive oil and table olive factories. This waste is currently used for multiple purposes, one of them being the extraction of bioactive substances, in particular phenolic compounds. The aims of this study were (i) to obtain a new polyphenolic extract from potassium hydroxide (KOH) -treated olive leaves; and (ii) to reduce acrylamide formation in black olives by using this extract. The results showed that olive leaves and leafless branches of the Manzanilla cultivar treated with 10 g/L KOH provide a solution that, concentrated under vacuum, had &
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2

Kiromah, Naelaz Zukhruf Wakhidatul, Sinta Wahyu Septiani, Wahyu Rahmatulloh, and Ari Purnomo Aji. "Penetapan Parameter Standar Simplisia dan Ekstrak Etanol Daun Ganitri (Elaeocarpus serratus L.)." PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia) 17, no. 1 (2020): 207. http://dx.doi.org/10.30595/pharmacy.v17i1.8833.

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Ceylon olive (Elaeocarpus serratus L.) leaves have shown many pharmacological effects. Standardization of crude drug and extract needs to be conducted to assure the quality of the said material and further to support the pharmacological, pharmacokinetics, and toxicity effects. Standardization of Ceylon olive leaf extract is carried out to determine the standard parameters of crude drug and ethanolic extract of Ceylon olive leaves. Determination of the quality standard of crude drug and extract includes specific and non-specific parameters. The extract was obtained from a 70% ethanol maceration
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3

Muhammad Khalid Saeed, Sadaf Javaria, Shakeeb Ullah, et al. "BIOACTIVE COMPOUNDS AND ANTIRADICAL CAPACITIES OF DIVERSE EXTRACTS OF OLEA EUROPAEA L. LEAVES FROM PAKISTAN." Health Sciences Journal 2, no. 2 (2024): 68–75. http://dx.doi.org/10.59365/hsj.2(2).2024.90.

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Background: There has been an increase in interest in studies for the extraction of biologically active compounds from natural sources during the past decade. The Oleaeuropaea L. tree, occasionally referred to as the olive, is one of the members of the Oleaceae family and is very significant historically and economically, particularly in Mediterranean countries. Olive leaves have a lofty phenolic compound, which offer them antioxidant properties and a decreased risk of illness. Aims: The aim of this study was to determine the bioactive compounds (polyphenol, flavonoids) and antioxidant activit
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4

Maslennikova, M. S., and N. L. Solovyova. "Development of Compositions and Technologies for Producing Tablets with Hydroxythyrozol-standardized Extract of Olive Leaves." Drug development & registration 10, no. 3 (2021): 47–53. http://dx.doi.org/10.33380/2305-2066-2021-10-3-47-53.

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Introduction. The article presents the results of a study of the physicochemical properties of dry extract of olive leaves, standardized by hydroxythyrozol - a biologically active substance that is part of the chemical composition of aerial parts of the olive tree.Aim. The purpose of the study is to develop tablet Formulations containing dry extract of olive leaves and to standardize by hydroxythyrozol by reversed-phase-HPLC method on the main substancecontent.Materials and methods. Substance of dry extract of olive leaves, microcrystalline cellulose (Avicel® PH-112), Aerosil® (Aeroperl® 300 P
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5

Kourti, Maria, Zoi Skaperda, Fotios Tekos, et al. "The Bioactivity of a Hydroxytyrosol-Enriched Extract Originated after Direct Hydrolysis of Olive Leaves from Greek Cultivars." Molecules 29, no. 2 (2024): 299. http://dx.doi.org/10.3390/molecules29020299.

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Nowadays, olive leaf polyphenols have been at the center of scientific interest due to their beneficial effects on human health. The most abundant polyphenol in olive leaves is oleuropein. The biological properties of oleuropein are mainly due to the hydroxytyrosol moiety, a drastic catechol group, whose biological activity has been mentioned many times in the literature. Hence, in recent years, many nutritional supplements, food products, and cosmetics enriched in hydroxytyrosol have been developed and marketed, with unexpectedly positive results. However, the concentration levels of hydroxyt
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6

Baptista, Ana, Beata Shymon, Beatriz Silva, et al. "Antibacterial Finishing of Cotton Bed Sheets using Olive Leaves Extract." U.Porto Journal of Engineering 8, no. 5 (2022): 31–40. http://dx.doi.org/10.24840/2183-6493_008.005_0005.

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The main goal of this project consisted of the conceptualization and development of a product related to the olive tree chemical features to monetize the wastes of the olive fruit exploitation. The most abundant by-product of the olive fruit harvest is the olive leaves, used as the raw material in this project. By following the steps of Chemical Product Design, it was decided to pursue the idea of creating antibacterial cotton bed sheets impregnated with olive leaves extract, mainly composed of oleuropein. The production process includes a pre-treatment of the olive leaves, oleuropein extracti
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7

Hussain Jehad Neamah. "Evaluation Effect of Phenolic Compounds in Aqueous Extracts of Pomegranate and Olive Leaves as Antioxidant and Antibacterial in beef." Journal of Wasit for Science and Medicine 9, no. 3 (2022): 6–16. http://dx.doi.org/10.31185/jwsm.303.

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The present study was aimed to know the effects of phenolic compounds were extracted from pomegranate and olive leaves which evaluated in beef. The results were showed effect plant extracts as antibacterial by agar diffusion method (Inhibition Zone Diameter) compared to antibiotics standard (cefamandol, cefixime and piperacillin) . On the other side, used Thiobarbituric acid reactive substances (TBARS) analysis to investigate on the meat oxidative , control treatment (C) showed exhibited the greater values of TBA, and lower TBA values were observed in pomegranate and olive leaves extract treat
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8

Bouallagui, Zouhaier, Asma Mahmoudi, Amina Maalej, Fatma Hadrich, Hiroko Isoda, and Sami Sayadi. "Contribution of Major Polyphenols to the Antioxidant Profile and Cytotoxic Activity of Olive Leaves." Anti-Cancer Agents in Medicinal Chemistry 19, no. 13 (2019): 1651–57. http://dx.doi.org/10.2174/1871520619666190416101622.

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Aim: This study was designed to investigate the phytochemical profile and the cytotoxic activities of the eco-friendly extracts of olive leaves from Chemlali cultivar. Materials and Methods: The Phenolic composition of olive leaves extracts, the antioxidant activity and the cytotoxic effects against MCF-7 and HepG2 cells were determined. Results: Olive leaves extracts showed relevant total polyphenols contents. Oleuropein was the major detected phenolic compound reaching a concentration of 16.9 mg/ml. The antioxidant potential of the studied extracts varied from 23.7 to 46.5mM Trolox equivalen
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9

Khanum, Fakhara, Tahir Zahoor, Muhammad Issa Khan, and Muhammad Asghar. "Biochemical Profile of Olive Leaves Grown in "Olive Valley" Pakistan." Biological Sciences - PJSIR 63, no. 1 (2020): 9–16. http://dx.doi.org/10.52763/pjsir.biol.sci.63.1.2020.9.16.

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This study was designed to determine the best olive variety for cultivation in Pakistan. The leaves of eight locally grown varieties were analyzed for levels of moisture, total solids, ash, fat, fibre, protein, K, Ca, Mg, Na, Fe, Mn, Zn and Cu levels. Leaves were then subjected to solvent extraction with each of water ratio in, 75% ethanol, 75% methanol, 95% ethanol and 95% methanol. The extract yield was significantly highest for 75% ethanol extract of all varieties. Significantly highest polyphenol and flavonoid contents were examined for Gemlik leaves extracted with 75% ethanol. We recommen
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10

Al-Baarri, A. N., F. P. Lestari, H. M. Wahda, Widayat, and A. M. Legowo. "Physicochemical properties of vacuum packaged snake fruits in the presence of olive leave extract." Food Research 4, S1 (2020): 250–55. http://dx.doi.org/10.26656/fr.2017.4(s1).s37.

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This research was done to investigate the effectiveness of the presence of olive leaf extract in vacuum packaging in maintaining the physicochemical properties of fresh-cut snake fruit under ambient temperature. The snake fruits were vacuum packaged in the presence of 3% (v/w) olive leave extract (OLE) and stored in room temperature for 8 days of storage. The physicochemical properties including color changes, firmness, and total dissolved solid (TDS) were observed. The results indicated that addition olive leaves extract in vacuum packaging gave the best result by inhibiting color changes by
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11

Leila, Dehghani, Emadi Mansoureh, and Modaresi Mehrdad. "Comparing the Effects of Olive Leaves and Alprazolam on Stress Reduction of Mice with Type 2 Diabetes." Pharmaceutical and Chemical Journal 5, no. 5 (2018): 77–81. https://doi.org/10.5281/zenodo.13924710.

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Olive leaves have antidepressant, antihypertensive, anti-diabetes, antioxidant, analgesic and anti-inflammatory properties. Current study was carried cut to compare the effects of olive leaves and alprazolam on stress reduction of mice with type 2 diabetes. Sixty mice in the weight range of 25 to 30 were divided into six groups: control, diabetes, alprazolam and 50, 100, and 200mg/kg of olive leaves’ extract.  All groups except control were induced diabetes three days before the test by intraperitoneal injection of 50mg/kg streptozotocin (STZ). After diagnosing the diabetes, groups
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12

Rashed, Shimaa A., Tamannouha I. Saad, and Salama M. El-Darier. "Potential aptitude of four olive cultivars as anticancer and antioxidant agents: oleuropein content." Rendiconti Lincei. Scienze Fisiche e Naturali 33, no. 1 (2022): 195–203. http://dx.doi.org/10.1007/s12210-022-01056-x.

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AbstractOlea europaea L. (olive, Oleaceae) constitutes a source of many bioactive compounds, which have recognized benefits for both human health and technological purposes. The present article was carried out to evaluate the biological activity of oleuropein (an ester of 2-(3,4-dihydroxyphenyl) ethanol (hydroxytyrosol) which has the oleosidic skeleton that is common to the secoiridoid glucosides of Oleaceae). It occurred in leaf extracts of the four olive cultivars (Chemlali, Manzanilla, Picaul and Toffahi) as a source for some anticancer and antioxidant agents and their consequences on the a
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13

Magyari-Pavel, Ioana Zinuca, Elena-Alina Moacă, Ștefana Avram, et al. "Antioxidant Extracts from Greek and Spanish Olive Leaves: Antimicrobial, Anticancer and Antiangiogenic Effects." Antioxidants 13, no. 7 (2024): 774. http://dx.doi.org/10.3390/antiox13070774.

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Olea europaea L. is the most valuable species of the Olea type, and its products offer a wide range of therapeutical uses. The olive tree has been extensively studied for its nourishing qualities, and the “Mediterranean diet”, which includes virgin olive oil as a key dietary component, is strongly associated with a reduced risk of cardiovascular disease and various malignancies. Olive leaves, a by-product in the olive harvesting process, are valued as a resource for developing novel phytomedicines. For this purpose, two ethanolic extracts obtained from Olivae folium from Spain (OFS) and Greece
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14

Himour, S., A. Yahia, and H. Belattar. "Oleuropein and Antibacterial Activities of Olea europaea L. Leaf Extract." European Scientific Journal, ESJ 13, no. 6 (2017): 342. http://dx.doi.org/10.19044/esj.2017.v13n6p342.

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In this study, we reported the determination of phenolic compounds in olive leaves by reversed phase HPLC/DAD and the evaluation of their in vitro activity against several microorganisms. These organisms might however, be causal agents of human intestinal and respiratory tract infections. Extract of the leaves of two varieties of Olea europaea L. (Chemlel and Dathier) was investigated for antibacterial activity against four pathogenic bacteria. Leaves extract was prepared using water and methanol (20/80) in a cold extraction process. The tested bacteria were Escherichia coli, Klebsiella pneumo
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15

Kiritsakis, Konstantinos, Athanasia M. Goula, Konstantinos G. Adamopoulos, and Dimitrios Gerasopoulos. "Valorization of Olive Leaves: Spray Drying of Olive Leaf Extract." Waste and Biomass Valorization 9, no. 4 (2017): 619–33. http://dx.doi.org/10.1007/s12649-017-0023-x.

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16

Danjolli-Hashani, Dua, and Sebnem Selen Isbilir. "Effect of Olea europaea L. (Domat and Gemlik var.) leaves extract against in vitro oxidative DNA damage." Herba Polonica 70, no. 2 (2024): 9–20. http://dx.doi.org/10.5604/01.3001.0054.6433.

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Reactive oxygen species formed in living organisms from various factors, cause to DNA damage, cytotoxicity and cell death. This study aims to investigate protective effect of two varieties of olive leaves extract against oxidative DNA damage induced by Fenton reaction. Gemlik variety (black olive) extract was found to have a slightly stronger protective effect than Domat (green olive) variety extract against oxidative DNA damage. Gemlik variety extract until did not show toxic effect on healthy liver cell line (AML12), it had shown cytotoxic effect on liver cancer cell line (Hep3B). However, D
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17

Bayram, Mustafa, Semra Topuz, and Cemal Kaya. "Zeytin Yaprağı Ekstraktı ve Oleuropeinin Antioksidan, Antimikrobiyal Aktivitesi, Gıdalarda Kullanım Olanakları." Turkish Journal of Agriculture - Food Science and Technology 8, no. 2 (2020): 337. http://dx.doi.org/10.24925/turjaf.v8i2.337-347.3039.

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Olive leaves which is one of the by-products of olive tree cultivation and olive processing industry, have been used in traditional folk medicine for centuries. In recent studies, it has been determined that olive leaf has many bioactivities and these effects have been associated with high phenolic compound content. The most dominant phenolic compound of olive leaf is oleuropein, which is the heterosidic ester of elenolic acid and 3,4-dihydroxyphenylethanol. Therefore, some studies have been carried out for extracting high value added compounds from olive leaves in recent years. Antioxidant an
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18

Benčić, Đani, Monika Barbarić, Ana Mornar, et al. "Oleuropein in olive leaf, branch, and stem extracts: stability and biological activity in human cervical carcinoma and melanoma cells." Acta Pharmaceutica 73, no. 4 (2023): 601–16. http://dx.doi.org/10.2478/acph-2023-0046.

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Abstract Olive leaves as a main byproduct of olive oil and fruit industry are a valuable source of phytochemicals such as polyphenols, with multiple biomedical effects. Apart from leaves, olive branches and stems make up a significant amount of olive waste. It is well known that the drying process and long-term storage affect the stability and concentration of polyphenols present in raw materials. For that matter, two different means of storing olive waste, at room temperature and +4 °C, were compared by determining the content of the polyphenol oleuropein (OLE) in olive leaf, branch, and stem
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19

Rashed, Khaled. "Phytocontent and Biological effects of Olea europaea: A Review." Plantae Scientia 5, no. 2 (2022): 36–44. http://dx.doi.org/10.32439/ps.v5i2.36-44.

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Olive tree (Olea europaea L., Oleaceae) leaves have been widely used in traditional herbal medicine to prevent and treat various diseases especially in Mediterranean countries. They contain several potentially bioactive com-pounds that may have hypoglycemic and hypolipidemic properties. Olea europaea is commonly known as Zaitoon. The ancient Egyptians, Greeks, Romans and other Mediterranean nations cultivated olives for its edible fruits and to obtain oil from them. Leaves of the tree became important when olive leaf extract was reported to be potent in reducing incidence of degenerative disea
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BEN MANSOUR-GUEDDES, Samia, Dhouha SAIDANA-NAIJA, Ameni BCHIR, and Mohamed BRAHAM. "Climate change effects on phytochemical compounds and antioxidant activity of Olea europaea." Notulae Botanicae Horti Agrobotanici Cluj-Napoca 48, no. 1 (2020): 436–55. http://dx.doi.org/10.15835/nbha48111615.

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To tolerate water shortage and high temperature, olive cv. ‘Meski’, the main variety of table olives in Tunisia, developed several biochemical changes. The hereby study focused on the adaptation of the olive tree to the climatic conditions, considering the evaluation of phenolic compounds, chlorophylls, carotenoids, saponin and steroid synthesis, as well as the evaluation of the antioxidant activity. The analyses were made upon fresh leaves collected from three coastal areas of Tunisia (North (sub-humid), center (higher semi-arid) and South (lower arid)) and using different leaves’ extracts. T
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Abdullah, B. N., K. K. Khudiar, and B. S. Toma. "Diuretic effects of aqueous extract of Olive Leaves (Olea europea) in adult male rats." Iraqi Journal of Veterinary Medicine 27, no. 1 (2003): 50–60. http://dx.doi.org/10.30539/ijvm.v27i1.1096.

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This study was carried out to investigate the effects of aqueous extract of olive leaves (Olea europea) on kidney functions. Eighteen adult male rats 
 three equal groups placed individually in were randomly divided in to metabolic cages and were handled as follows: group (C) served as control group; rats in group (T1) were intubated (90 mg/kg B.W.) of aqueous extract of 
 group T2 were intubated (0.8 mg/kg B.W.) of olive leaves and rats in ammuretic. Blood and urine samples were collected after 24 hours of 
 significant increase in urinary output intubation. The results showed
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Centrone, Mariangela, Mariagrazia D’Agostino, Graziana Difonzo, et al. "Antioxidant Efficacy of Olive By-Product Extracts in Human Colon HCT8 Cells." Foods 10, no. 1 (2020): 11. http://dx.doi.org/10.3390/foods10010011.

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The production of olive oil is accompanied by the generation of a huge amount of waste and by-products including olive leaves, pomace, and wastewater. The latter represents a relevant environmental issue because they contain certain phytotoxic compounds that may need specific treatments before the expensive disposal. Therefore, reducing waste biomass and valorizing by-products would make olive oil production more sustainable. Here, we explore the biological actions of extracts deriving from olive by-products including olive pomace (OP), olive wastewater (OWW), and olive leaf (OLs) in human col
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23

Al- Jubury, Najlaa Obaies Halol. "Effects of Olive Leaves Extract on Urea, Uric Acid and Creatinine Concentrations in Serum of Heat Stressed Male Rabbits." Journal of Wasit for Science and Medicine 6, no. 1 (2022): 1–11. http://dx.doi.org/10.31185/jwsm.214.

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The purpose of this study is to investigate the positive effects of olive leaves extract on the alteration of some renal function test (urea, uric acid and creatinine) in serum of male rabbits that have been reared under heat stress conditions. Thirty , New Zealand white male rabbits,(12-14 weeks old and 1500-2000 gm in weight) are individually caged, for 30 days. The animals are divided into six groups(5 animals for each) control group and 5 experimental groups (reared under heat stress environment). The first experimental group heat stressed only, the other two groups have received every day
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Cuffaro, Doretta, Simone Bertini, Marco Macchia, and Maria Digiacomo. "Enhanced Nutraceutical Properties of Extra Virgin Olive Oil Extract by Olive Leaf Enrichment." Nutrients 15, no. 5 (2023): 1073. http://dx.doi.org/10.3390/nu15051073.

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(1) Background: Nowadays, the health-promoting properties of extra virgin olive oil (EVOO), including the antioxidant and anti-inflammatory actions, are well recognized and mainly attributed to the different polyphenols, such as oleocanthal and oleacein. In EVOO production, olive leaves represent a high value by-product, showing a wide spectrum of beneficial effects due to the presence of polyphenols, especially oleuropein. Here we report the study of olive leaf extract (OLE)-enriched EVOO extracts, obtained by adding different percentages of OLE to EVOO in order to ameliorate their nutraceuti
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Leonova, Victoria Nodaryevna, and Anna Gurgenovna Kuregyan. "CHOICE OF THE OPTIMAL EXTRACTANT AND CONDITIONS FOR THE ANALYSIS OF PHENOLIC COM-POUNDS FROM EUROPEAN OLIVE LEAVES (OLEA EUROPAEA L.)." chemistry of plant raw material, no. 3 (September 25, 2024): 198–206. https://doi.org/10.14258/jcprm.20240312655.

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The leaves of the European olive (Olea europaea L.) are characterized by a high content of bioactive polyphenol derivatives that have antioxidant, antiviral, anti-inflammatory, cardioprotective, hypotensive, antitumor effects. The aim of the work is to select the optimal extractant and conditions for the analysis of phenolic compounds from European olive leaves. A comparative analysis of the seven obtained extracts was carried out by spectrophotometry and thin layer chromatography (TLC). The UV spectra of solutions of the compared extracts show an absorption maximum at 280±2 nm, which can be a
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Al-Dabbas, Maher M., Rawan Al-Jaloudi, Hani J. Hamad, et al. "Antioxidant, Antibacterial, and Antidiabetic Activities of Different Extracts from Wild Olive Leaves Grown in United Arab Emirates." Processes 13, no. 4 (2025): 998. https://doi.org/10.3390/pr13040998.

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Olive leaves (Olea europaea L.) are a source of natural bioactive compounds with various health benefits and are often considered agricultural waste. This study aimed to evaluate the antioxidant, antibacterial, and antidiabetic activities of an infused aqueous extract and ultrasonic-assisted extracts (aqueous, methanol, ethyl acetate, and hexane) from wild olive leaves grown in the United Arab Emirates (UAE). The aqueous-infused extract exhibited the highest total phenolic content (TPC; 91.9 mg GAE/g extract), the highest reducing power activity, the lowest IC50 value for diphenyl-1-picrylhydr
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Sami, Ullah* Javeid Iqbal Aman Ullah Khan Tajala Aman Ghulam Razaque. "NEURO AND ANALGESIC ACTIVITIES OF OLIVE LEAF METHANOLIC CRUDE EXTRACT." INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES 05, no. 03 (2018): 1814–21. https://doi.org/10.5281/zenodo.1210801.

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Genus Olea (Oleaceae) are prominent for its therapeutic value and are comprised in British and Indian pharmacopeias. In Pakistan Olea europaea leaves widely spread in Baluchistan province, NWFP, Punjab and in northerly areas at increase of 900 to 2900 m. In Balochistan it is found in sherani and zirat districts. Olea europaea leaves have multipotential remedial properties Present study was conducted for the investigation of some neurologic, properties of medicinal plant olea europea (oleaceae). The crude methanolic herbal extract was evaluated for its Neuropharacological aspects by forced swim
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Journal, Baghdad Science. "Study the Effects of Olive Leaves Extracts in the activity of the enzyme GOT and their Biological Activities." Baghdad Science Journal 14, no. 1 (2017): 48–59. http://dx.doi.org/10.21123/bsj.14.1.48-59.

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The olive tree, has been used it is important plant for the time being some of their parts on a large scale in the treatment of gastrointestinal disorders and stimulate circulation . Moreover, it is used as antibacterial material and also to address some of the respiratory system, diabetes, food preservation osteoporosis. This study involved the collection of olive leaves from different areas in Baghdad / Iraq. These leaves have been harvested, wash it, then dried and crushed, where the study aimed to identify the active ingredients and chemical elements in the olive leaf as well as its effect
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Sara, Himour, Belhain Hayat, and Bouketta Mehbouba. "Anticoagulant Activities of Olea Europaea Leaves and Fruit Extract." European Scientific Journal, ESJ 13, no. 30 (2017): 90. http://dx.doi.org/10.19044/esj.2017.v13n30p90.

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The objective of this study is the evaluation of the anticoagulant activity of polyphenols obtained from extracts of the leaves, and fruits of olive (Olea europaea L.) of four varieties cultivated in the station Maazouzi Lakhdar (Mila, Algeria). The anticoagulant activity of the polyphenolic extracts, of the leaves and fruits of olive have been evaluated in vitro, using the test of Quick time (QT). The values of clotting time a showed a surprising anticoagulant activity on the exogenous pathway of coagulation, significant in the case of leaves and fruits of the Chemlel variety.
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Badawi, Sally, Saleh Ahmed, and Nabeel Al -Ani. "Effect of Ethanolic Olive leaf and its Callus Ethanol Extracts in Alloxan- induced Diabetic mice (Blood glucose and lipid profiles)." Journal of Biotechnology Research Center 7, no. 2 (2013): 63–69. http://dx.doi.org/10.24126/jobrc.2013.7.2.268.

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This study was designed to test the lipid-lowering and antidiabetic activities of olive leaf and its callus extract. Diabetes in mice was induced by intraperitoneal injections of alloxan. The serum glucose and serum lipid were examined. Diabetic mice showed hypeglycemia, hypelipidemia. The administration, for 2 weeks of olive leaf and its callus extracts significantly decreased the Total cholesterol (TC). Triglycerides (TG). Low density lipoprotein (LDL), very low density lipoprotein (VLDL). Both types of olive extracts had significant hypoglycemic effects on blood glucose levels in diabetic m
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Borjan, Dragana, Maja Leitgeb, Željko Knez, and Maša Knez Hrnčič. "Microbiological and Antioxidant Activity of Phenolic Compounds in Olive Leaf Extract." Molecules 25, no. 24 (2020): 5946. http://dx.doi.org/10.3390/molecules25245946.

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According to many reports, phenolic compounds isolated from olive leaves have very good biological activities, especially antimicrobial. Presently, the resistance of microorganisms to antibiotics is greater than ever. Therefore, there are numerous recent papers about alternative solutions for inhibiting their influence on human health. Olive leaf is studied as an important source of antimicrobials with low cost and used in medicine. Numerous publications on involving green technologies for isolation of active compounds from olive leaves have appeared over the past few decades. The present revi
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Vasilopoulou, Konstantina, Georgios A. Papadopoulos, Styliani Lioliopoulou, et al. "Effects of Dietary Supplementation of a Resin-Purified Aqueous-Isopropanol Olive Leaf Extract on Meat and Liver Antioxidant Parameters in Broilers." Antioxidants 12, no. 9 (2023): 1723. http://dx.doi.org/10.3390/antiox12091723.

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Olive leaves are byproducts οf the agro-industrial sector and are rich in bioactive compounds with antioxidant properties. They could be supplemented in poultry diets powdered or less frequently as extracts to improve performance, health and product quality. The objective of this study was to investigate the possible beneficial effects of an aqueous isopropanol olive leaf extract—purified through filtration (250–25 µm) and a resin (XAD-4)—when supplemented in broiler chickens’ diets, on meat quality parameters, focusing mainly on antioxidant parameters as there is limited published information
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Alcántara, Cristina, Tihana Žugčić, Radhia Abdelkebir, et al. "Effects of Ultrasound-Assisted Extraction and Solvent on the Phenolic Profile, Bacterial Growth, and Anti-Inflammatory/Antioxidant Activities of Mediterranean Olive and Fig Leaves Extracts." Molecules 25, no. 7 (2020): 1718. http://dx.doi.org/10.3390/molecules25071718.

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Mediterranean plants, such as fig and olive leaves, are well-known to exert beneficial effects in humans because of the presence of a wide range of bioactive compounds. However, scarce information regarding the impact of extraction methods, such as ultrasound and types of solvents, on their profile of antioxidant and anti-inflammatory compounds is provided. In addition, no information is available on the effects of extraction methods and solvents on the inhibition of pathogenic bacteria or promoting probiotic growth. In this scenario, this study was aimed to study the effects of ultrasound-ass
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Werghemmi, W., S. Abou Fayssal, H. Mazouz, H. Hajjaj, and L. Hajji. "Olive and green tea leaves extract in Pleurotus ostreatus var. florida culture media: Effect on mycelial linear growth rate, diameter and growth induction index." IOP Conference Series: Earth and Environmental Science 1090, no. 1 (2022): 012020. http://dx.doi.org/10.1088/1755-1315/1090/1/012020.

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Abstract The exponential disposal of agro-industrial wastes onto the environment has endangered all forms of life. The implementation of these wastes in mushroom production is an eco-friendly and promising solution. The effect of olive and tea leaves extracts represented in culture media treatments: potato dextrose agar (PDA) 80% + tea extract (TE) 20% (T2), PDA 80% + olive extract (OE) 20% (T3), PDA 80% + OE 10% + TE 10% (T4), PDA 70% + OE 20% + TE 10% (T5) on mycelial growth diameter (MGD) and linear growth rate (MLGR) of Pleurotus ostreatus var. florida was compared to the one of PDA used a
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Al-khafaji, Eussur Noory, Maryam Mansoor Mathkoor, and H. H. Al-Anbari. "Preparation and Characterization of Silver Nanoparticles Using Rosemary and Olive Leaf Aqueous Extracts." IOP Conference Series: Earth and Environmental Science 1158, no. 10 (2023): 102002. http://dx.doi.org/10.1088/1755-1315/1158/10/102002.

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Abstract Nano technology is single of the current technologies that are used in several playing field as well as agriculture, Nano-particles are produced in various ways, one of which is the biological method, which is one of the easy, fast, inexpensive and environmentally safe methods. This reference study deals with the latest studies on the manufacture of microorganisms and plant extracts, Biosynthesis of metallic nanoparticles using plant extracts. This study aims to use extracts of olive leaves and rosemary leaves as a biological agent to reduce silver nitrate to silver nanoparticles and
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Cedola, Annamaria, Carmen Palermo, Diego Centonze, Matteo Alessandro Del Nobile, and Amalia Conte. "Characterization and Bio-Accessibility Evaluation of Olive Leaf Extract-Enriched “Taralli”." Foods 9, no. 9 (2020): 1268. http://dx.doi.org/10.3390/foods9091268.

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Olive leaves are rich in many compounds precious for human health. Due to this property, the current study was aimed to valorize the extract from this by-product in a cereal-based food, very popular all around the world, the “taralli”. To this aim, ultrasound-assisted extraction was applied to dried olive leaves to obtain the extract, used as “taralli” ingredient, instead of white wine. The “taralli” with and without extract was subjected to in vitro digestion to assess the quantity of polyphenolic compounds released in the gastrointestinal tract to become available for absorption. Total conte
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Mustafa, Farhang A., and Khabat A. Ali. "The Protective Rolls of Taraxacum officinale against Carbone Tetrachloride Infarction in the Liver." Cihan University-Erbil Scientific Journal 7, no. 1 (2023): 39–47. http://dx.doi.org/10.24086/cuesj.v7n1y2023.pp39-47.

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Carbon tetrachloride (CCl4) is a liquid that is colorless, transparent, inflammable, and volatile. Its central carbon atom is surrounded by four Cl- atoms. As a result, the objective of this effort was to estimate the anti-oxidant properties of silver nanoparticles (AgNPs) made utilizing aqueous plant extracts from Taraxacum officinale leaves. A green synthesis of AgNPs using a synergistic aqueous extract from T. officinale leaves was tested against liver damage in rats caused by CCl4. The rats were randomly distributed into seven groups: Group 1: Control group, Group 2: Olive oil group, Group
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Albogami, Sarah, and Aziza  Hassan. "Assessment of the Efficacy of Olive Leaf (Olea europaea L.) Extracts in the Treatment of Colorectal Cancer and Prostate Cancer Using In Vitro Cell Models." Molecules 26, no. 13 (2021): 4069. http://dx.doi.org/10.3390/molecules26134069.

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Cancer is one of the most serious public health issues worldwide, ranking second only to cardiovascular diseases as a cause of death. Numerous plant extracts have extraordinary health benefits and have been used for centuries to treat a variety of ailments with few side effects. Olive leaves have a long history of medicinal and therapeutic use. In this study, the anti-cancer properties of an olive leaf extract were investigated in vitro using colorectal and prostate cancer cell lines (HT29 and PC3, respectively). A high-performance liquid chromatography analysis showed that the olive leaf extr
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Miloradovic, Zoran, Maja Gvozdenov, Djurdjica Jovovic, et al. "Effect of Olea europea L. leaf extract on haemodynamic status and lipid peroxidation in spontaneously hypertensive rats." Veterinarski glasnik 67, no. 5-6 (2013): 303–15. http://dx.doi.org/10.2298/vetgl1306303m.

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Hypertension is one of the main causes of cardiovascular disorders and since ancient times olive tree leaves have been used in its therapy. However the mechanisms of their atihypertensive effect have not been sufficiently explained yet. The main objective of our study was to investigate acute effect of olive tree leaves extract on haemodynamics and lipid peroxidation in rats with congenital hypertension under normal and blocked synthesis of nitric oxide. For the purpose of our research, there were used olive tree leaf extract EFLA? 943 as well as inhibitor of nitric oxide synthase enzyme L-NAM
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Vidal, Alfonso M., Manuel Moya, Sonia Alcalá, Inmaculada Romero, and Francisco Espínola. "Enrichment of Refined Olive Oils with Phenolic Extracts of Olive Leaf and Exhausted Olive Pomace." Antioxidants 11, no. 2 (2022): 204. http://dx.doi.org/10.3390/antiox11020204.

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Refined olive oils (ROOs) are commonly enriched with synthetic antioxidants. Antioxidant extracts obtained from natural products can be used to improve the stability of these oils. In this study, ROOs were enriched through the addition of phenolic extracts from olive leaves (OLs) and exhausted olive pomace (EOP). In addition to replacing synthetic antioxidants with natural ones, this results in the valorization of these olive-derived biomasses. The most suitable method for mixing and enriching refined oils was probe-type ultrasonication using lecithin as the emulsifier. Thereafter, the change
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Hinad, Ibrahim, Youssef S’hih, Radia El Gui, Aboubaker Elhessni, Abdelhalim Mesfioui, and Moulay laarbi Ouahidi. "Acute and subacute toxicity study of the methanolic extract of olea europea.L leaves in Wistar rat." E3S Web of Conferences 319 (2021): 01094. http://dx.doi.org/10.1051/e3sconf/202131901094.

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Olea europea.L (olive tree) is a plant widely used in the world. Its leaves have an extensive use in traditional herbal medicine to prevent and/or treat several diseases especially in Mediterranean regions. Despite this, research into the study of its toxicity is very limited in the literature. For this, this study aims to study the acute and subacute toxicity of methanolic extract olive leaves in Wistar rats. To study acute toxicity, four dose levels (50,300,2000 and 5000 mg/kg body weight) were tested by single oral administration to Wistar rats. The subacute toxicity for 28 days was conduct
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Ozkan, M., F. Z. Biber Muftuler, A. Yurt Kilcar, E. I. Medine, and P. Unak. "Isolation of hydroxytyrosol from olive leaves extract, radioiodination and investigation of bioaffinity using in vivo/in vitro methods." ract 101, no. 9 (2013): 585–93. http://dx.doi.org/10.1524/ract.2013.2068.

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Summary It is known that medicinal plants like olive have biological activities due to their flavonoid content such as olueropein, tyrosol, hydroxytyrosol etc. In current study, hydroxytrosol (HT) which is one of the major phenolic compounds in olive, olive leaves and olive oil, was isolated after methanol extraction and purification of olive leaves which are grown in the northern Anatolia region of Turkey. The isolated HT was radiolabeled with 131I (131I-HT) and the bioaffinity of this radiolabeled component of olive leaves extract was investigated by using in vivo/in vitro methods. It was fo
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Ali, Alaa Abbas, Sabah Abd Fleih, Razzaq O. Idan, and Harith M. Aziz. "Response of olive seedlings for treatment with licorice and yeast extract." Journal of Kerbala for Agricultural Sciences 4, no. 4 (2017): 56–68. http://dx.doi.org/10.59658/jkas.v4i4.255.

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This search was conducted in the lath of the Department of Horticulture and landscape – College of Agriculture / Kerbala University for the summer season 2016 on olive seedlings Khadairytype (high Syrian oil type) to see the effect of treatment with licorice and yeast extracts in the growth and development of olive seedlings ; 27 olive seedlings with one year old planted in mixed in 5-kg perforated polyethylene bags were divided into three groups of three replicates and treated with three levels of licorice and yeast extracts (0, 4 and 8) g.L-1.
 A 3 × 3 experiment was carried out with (R
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Zerrouki, Kheira, and Ali Riazi. "Antibacterial effect of phenolic extract of olive tree on some pathogenic bacteria." South Asian Journal of Experimental Biology 13, no. 1 (2023): 39–45. http://dx.doi.org/10.38150/sajeb.13(1).p39-45.

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There is a growing problem of antibiotic resistance that requires new approaches and an urgent research on novel therapeutic strategies and antibacterial drugs. Olive fruit is one of the most popular mediterranian food. Phenolic metabolites (polyphenols) exhibit a series of biological properties that promotes human health. Olive tree (Olea europaea) can confer significant benefits to the human health, which motivated us to undertake the present study on its main benefits molecules (polyphenols) especially of other olive parts that are less used in humain therapy, since there are numerous findi
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45

Xie, Pujun, Lorenzo Cecchi, Maria Bellumori, et al. "Phenolic Compounds and Triterpenes in Different Olive Tissues and Olive Oil By-Products, and Cytotoxicity on Human Colorectal Cancer Cells: The Case of Frantoio, Moraiolo and Leccino Cultivars (Olea europaea L.)." Foods 10, no. 11 (2021): 2823. http://dx.doi.org/10.3390/foods10112823.

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Phenolic and triterpenoid compounds of the olive tree are recognized as having a key role in health promotion, thanks to their multiple protective actions in humans. To expand the source of these bioactive compounds, the phenolic and triterpenoid profiles of leaf, branch, destoned fruit, destoned pomace, shell, seed, and extra virgin olive oil from the Frantoio, Leccino, and Moraiolo olive cultivars were simultaneously characterized by HPLC-DAD-MS. Overall, 43 molecules were quantitated and expressed on the obtained dry extracts. Oleuropein was mainly concentrated in branches (82.72 g/kg), fru
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Adel, G. Abdel-Razek, Noah Badr A., and G. Shehata Mohamed. "Characterization of Olive Oil By-products: Antioxidant Activity, Its Ability to Reduce Aflatoxigenic Fungi Hazard and Its Aflatoxins." Annual Research & Review in Biology 14, no. 5 (2017): 1–14. https://doi.org/10.9734/ARRB/2017/35065.

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<strong>The Aim:</strong> The aim of this study is to explore a new application for turning low value byproducts to value added bioactive components using a simple technique. <strong>Study Design:</strong> The large amounts of byproducts resulted had an environmentally harmful; the phenolic components were extracted using aqueous isopropanol from olive leaves and pomace. <strong>Place and Duration of Study:</strong> samples were analysed in laboratories of Fats and Oils Department, Toxicology and Food Contaminants; National Research Centre; and in Department of Food Technology, City of Scienti
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Burò, Ilaria, Valeria Consoli, Angela Castellano, Luca Vanella, and Valeria Sorrenti. "Beneficial Effects of Standardized Extracts from Wastes of Red Oranges and Olive Leaves." Antioxidants 11, no. 8 (2022): 1496. http://dx.doi.org/10.3390/antiox11081496.

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The awareness of the large amount of waste produced along the food chain, starting in the agricultural sector and continuing across industrial transformation to the domestic context, has in recent years also aroused strong concern amongst the public, who are ing about the possible consequences that this could have on environmental sustainability, resource waste and human health. The aim of the present research is the recovery of substances with high added value from waste and by-products typical of the Mediterranean area, such as the residue from the industrial processing of red oranges, calle
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El-Kholany, A. S., M. M. Abdelmegeed, M. A. Abd-Elraheem, M. S. Deraz, and M. A. Elshaer. "Chemical Evaluation and Biological Activity of Olive Leaves Extract." Al-Azhar Journal of Agricultural Research 47, no. 1 (2022): 35–45. http://dx.doi.org/10.21608/ajar.2022.266482.

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Monteleone, Julieta Ines, Elisa Sperlinga, Laura Siracusa, et al. "Water as a Solvent of Election for Obtaining Oleuropein-Rich Extracts from Olive (Olea europaea) Leaves." Agronomy 11, no. 3 (2021): 465. http://dx.doi.org/10.3390/agronomy11030465.

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Leaves from Olea europaea represent one of the main by-products of the olive oil industry, containing a plethora of bioactive compounds with several promising activities for human health. An organic solvent-free extraction method was developed for the recovery of olive leaf phenols, which obtained an extract containing oleuropein in high amounts. A comparison of various extraction media is reported, together with the total phenolic content, DPPH (2,2-Diphenyl-1-picrylhydrazyl) content, ORAC (oxygen radical absorbance capacity), and polyphenol oxidase activity of the corresponding extracts. The
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Kashaninejad, M., M. T. Sanz, B. Blanco, S. Beltrán, and S. Mehdi Niknam. "Freeze dried extract from olive leaves: Valorisation, extraction kinetics and extract characterization." Food and Bioproducts Processing 124 (November 2020): 196–207. http://dx.doi.org/10.1016/j.fbp.2020.08.015.

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