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Dissertations / Theses on the topic 'Omega-3 and C-reactive protein-hs'

Author: Grafiati

Published: 4 June 2021

Last updated: 1 February 2022

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1

Moran, Megan. "The effect of omega-3 enhanced fish consumption on C-reactive protein levels in post-menopausal women." Morgantown, W. Va. : [West Virginia University Libraries], 2010. http://hdl.handle.net/10450/10902.

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Thesis (M.S.)--West Virginia University, 2010.<br>Title from document title page. Document formatted into pages; contains v, 82 p. : ill. (some col.). Includes abstract. Includes bibliographical references (p. 33-35).

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2

Santos, Eduardo Porto dos. "Efeitos da suplementação de Omega-3 no processo inflamatório e dano muscular induzidos por estresse físico e restrição alimentar em militares." Universidade Federal da Paraíba, 2010. http://tede.biblioteca.ufpb.br:8080/handle/tede/4309.

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Made available in DSpace on 2015-04-17T15:03:05Z (GMT). No. of bitstreams: 1 arquivototal.pdf: 503890 bytes, checksum: 99e21ac9bda74afe0bcd03f4094569ee (MD5) Previous issue date: 2010-03-29<br>Coordenação de Aperfeiçoamento de Pessoal de Nível Superior - CAPES<br>The literature has several studies showing the anti-inflammatory and protective against cardiovascular disease, the polyunsaturated fatty acids are omega-3 intake of fatty acids has been recommended as a way to prevent heart disease and improve heart function. There are few studies involving the anti-inflammatory effect of fatt

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3

Drager, Christopher John. "Effect of DHA supplementation on muscle damage and inflammation during the first two weeks of a novice resistance training program." Thesis, Virginia Tech, 2013. http://hdl.handle.net/10919/19254.

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Aim: The purpose of this study was to investigate docosahexaenoic acid (DHA) ingestion on muscle damage and inflammation during the first two weeks of a novice resistance training (RT) program. Methods: This study was a placebo-controlled, double-blind design. Forty-one healthy untrained males between the ages of 18 and 28 years consumed 2,000 mg/d of either DHA or corn oil (PCB) for 44 days including a 28 day loading period. Serum fatty acids were analyzed to determine treatment efficacy. During the 17 day training period, an acute eccentric exercise bout was implemented followed by a full-b

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4

Strandberg, Emelie. "Skeletal Muscle Mass & Function in Older Women : Health-Enhancing Influences of Combined Resistance Exercise & Diet." Doctoral thesis, Örebro universitet, Institutionen för hälsovetenskaper, 2017. http://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-61234.

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Ageing is accompanied by a progressive decline in skeletal muscle mass and strength which may lead to impaired ability to perform activities of daily living in older adults. Although the exact cause of the gradual decline in muscle mass is unknown, identifying efficient strategies aiming to prevent age-related loss of muscle mass and strength is important in order to promote healthy ageing. The overall aim of this thesis was to explore the effects of resistance training alone or combined with a healthy diet on skeletal muscle mass and function of healthy recreationally active older women and t

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5

Oliveira, Julicristie Machado de. "Efeito dos ácidos graxos ômega-3 de origem marinha em parâmetros bioquímicos, antropométricos e inflamatórios de adultos que vivem com HIV em terapia antirretroviral: revisão da literatura e ensaio clínico." Universidade de São Paulo, 2011. http://www.teses.usp.br/teses/disponiveis/6/6138/tde-27052011-105941/.

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Introdução: A terapia antirretroviral (ART) mudou o curso da Aids, porém está associada a alterações metabólicas e aumento do risco de doenças cardiovasculares. Objetivo: Avaliar o efeito da suplementação com ácidos graxos ômega-3 de origem marinha no perfil lipídico, na homeostase da glicose, na distribuição de gordura corporal e nos marcadores inflamatórios de adultos com HIV em ART. Métodos: Artigo 1. Trata-se de uma revisão sistemática da literatura com metanálise. Realizou-se busca por ensaios clínicos na base de dados PubMed; 33 artigos foram localizados, seis cumpriram os critérios de i

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6

Norris, Judy Barnett. "Structural characterization of omega loop peptides from cytochrome c." Thesis, Georgia Institute of Technology, 1993. http://hdl.handle.net/1853/27450.

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7

Villegas-MeÌndez, Ana. "Endothelial cell protein C receptor interactions with protein C and proteinase 3." Thesis, Imperial College London, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.417119.

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8

Bothma, Karien. "The involvement of lipid and protein oxidation in hypertension : the SABPA study / Karien Bothma." Thesis, North-West University, 2012. http://hdl.handle.net/10394/8652.

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Oxidative stress, caused by increased levels of reactive oxygen species (ROS)and reactive nitrogen species (RNS) and/or a decrease in antioxidant capacity, can result in the oxidation of various bio-molecules, such as proteins, lipids and deoxyribonucleic acid (DNA). These oxidized bio-molecules may contribute to pathologies such as cardiovascular diseases, neurodegenerative disorders and cancer. The Sympathetic Activity and Ambulatory Blood Pressure in Africans (SABPA) study was initiated in 2008 to investigate the coping styles and catecholamine metabolic markers of Africans, contributing to

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9

Wardell, Andrew D. "Expression and characterisation of the hepatitis C virus non-structural protein 3." Thesis, Imperial College London, 1999. http://hdl.handle.net/10044/1/11239.

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10

Yang, Zhaogang. "ADENOSINE RECEPTOR MEDIATED PROTEIN KINASE C ACTIVATION IN THE HEART." The Ohio State University, 2012. http://rave.ohiolink.edu/etdc/view?acc_num=osu1338320892.

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11

Fox, Henrik. "Untersuchungen zur Rolle des Signal Transducer and Activator of Transcription (STAT) 3 bei der transkriptionellen Regulation der Synthese des C-reaktiven Proteins." [S.l. : s.n.], 2007. http://nbn-resolving.de/urn:nbn:de:bsz:289-vts-58908.

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12

Wagey-Radjawane, Theophilia Ravenska Elizabeth. "A role of protein kinase C (PKC) and phosphatidylinositol-3-kinase (PI 3-K) in motoneuron dysfunction." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2001. http://www.collectionscanada.ca/obj/s4/f2/dsk3/ftp04/NQ61192.pdf.

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13

Street, Andrew A. "Activation of phosphatidylinositol 3-kinase signalling by the hepatitis C virus NS5A protein." Thesis, University of Leeds, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.417733.

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14

Desai, Shraddha R. "Role of Protein Kinase C-iota in Glioblastoma." Scholar Commons, 2011. http://scholarcommons.usf.edu/etd/3070.

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The focus of this research was to investigate the role of protein kinase C-iota (PKC-é) in the regulation of Bad function, a pro-apoptotic member of the Bcl-2 family and Cdk7 function, a master cell cycle regulator in glioblastoma. The results were obtained from the human glial tumor derived cell lines, T98G and U87MG. In these cells, PKC-é co-localized and directly associated with Bad as shown by immunofluorescence, immunoprecipitation, and Western blotting. Furthermore, in-vitro kinase activity assay showed that PKC-é directly phosphorylated Bad at phospho specific residues, S112, S136 and

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15

Lopes, Izabela Aparecida. "Identificação dos mecanismos de regulação das células Natural Killer pelo fator de transcrição C/EBPG (CCAAT/enhancer binding protein gamma)." Universidade de São Paulo, 2018. http://www.teses.usp.br/teses/disponiveis/17/17154/tde-13092018-145344/.

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Os C/EBP (CCAAT/enhancer-binding proteins) são uma família de fatores de transcrição implicados numa variedade de processos da hematopoese, regulando tanto a diferenciação terminal como a proliferação celular. Dentre estes, sabe-se que o C/EBP gamma (C/EBPG) está envolvido na maturação funcional de células Natural Killer (NK). Entretanto, os mediadores dessa regulação não são conhecidos. As células NK são linfócitos com funções efetoras de citotoxicidade e de produção de citocinas, dependentes de um equilíbrio dinâmico entre a expressão de receptores ativatórios e inibitórios bem como de recep

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16

Pääjärvi, Gerd. "Xenobiotics-induced phosphorylations of MDM2 /." Stockholm, 2006. http://diss.kib.ki.se/2006/91-7140-951-3/.

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17

Cardoso, Andrea Rodrigues. "Mapeamento global de interações proteicas nas vias de sinalização mediadas por c-di-GMP de Pseudomonas aeruginosa." Universidade de São Paulo, 2016. http://www.teses.usp.br/teses/disponiveis/76/76132/tde-17052016-094656/.

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A persistência bacteriana correlacionada à formação de biofilmes bacterianos é, há algum tempo, fonte de grande preocupação médica em virtude de sua ampla associação com a dificuldade de tratamento de infecções crônicas. Por outro lado, as perspectivas de utilização de biofilmes bacterianos em novas aplicações biotecnológicas e até mesmo para fins terapêuticos são promissoras. Há, portanto, grande interesse em compreender os mecanismos que levam as células bacterianas a deixar o estado planctônico, de vida livre, e associarem-se nesses conglomerados celulares altamente complexos. Ao longo das

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18

Aydin, Cihan. "Hepatitis C Virus Non-Structural Protein 3/4A: A Tale of Two Domains: A Dissertation." eScholarship@UMMS, 2012. https://escholarship.umassmed.edu/gsbs_diss/626.

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Two decades after the discovery of the Hepatitis C Virus (HCV), Hepatitis C infection still persists to be a global health problem. With the recent approval of the first set of directly acting antivirals (DAAs), the rate of sustained viral response for HCV-infected patients increased significantly. However, a complete cure has not been found yet. Drug development efforts primarily target NS3/4A protease, bifunctional serine protease-RNA helicase of HCV. HCV NS3/4A is critical in viral function; protease domain processes the viral polyprotein and helicase domain aids replication of HCV genome b

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19

Idicula, Babu Benoy. "Epigallocatechin-3-gallate and recombinant human activated protein C and the modulation of acute pancreatitis." Thesis, University of Manchester, 2012. https://www.research.manchester.ac.uk/portal/en/theses/epigallocatechin3gallate-and-recombinant-human-activated-protein-c-and-the-modulation-of-acute-pancreatitis(5fc797e9-cf5b-4aab-841d-62c3a8cd82c6).html.

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Effective management of acute pancreatitis has for centuries eluded mankind. The disease has a wide spectrum of presentation; the milder form is usually a self limiting condition, whereas the severe form presents as a highly morbid and frequently lethal attack. The ability to predict disease progression on admission would aid in the comprehensive and multidisciplinary management of patients. The perfect predictor of disease progression has been an elusive factor hindering the management of the disease. On systematically reviewing literature and identifying appropriate biochemical markers in pr

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20

Rojnuckarin, Ponlapat. "Mitogen-activated protein kinase pathways in megakaryocyte development /." Thesis, Connect to this title online; UW restricted, 2001. http://hdl.handle.net/1773/9200.

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21

Scott, Robert Orlando. "The effects of fluid shear stress on the activity of protein kinase C, phosphatidylinositol 3-kinase and Rho in aortic endothelial cells." Diss., Georgia Institute of Technology, 1996. http://hdl.handle.net/1853/25668.

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22

LeBron, Cynthia. "Regulation of MDMX nuclear import and degradation by Chk2 and 14-3-3." [Tampa, Fla.] : University of South Florida, 2007. http://purl.fcla.edu/usf/dc/et/SFE0001992.

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23

Martin, Morgan Mackensie. "Functional analysis of hepatitis C virus non-structural protein (NS) 3 protease and viral cofactor NS4A." Thesis, University of British Columbia, 2008. http://hdl.handle.net/2429/1522.

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The hepatitis C virus (HCV) was identified in 1989 as the major causative agent of transfusion-associated non-A, non-B hepatitis and today represents a worldwide health crisis with prevalence estimates of 2.2%. HCV-specific therapeutics have never been more urgently needed. One of the validated drug targets is the non-structural (NS) protein 3 (NS3) membrane-bound protease. The major aim of this thesis was characterization of NS3 allosteric activation by its viral cofactor, NS4A. We hypothesized that there would be specific residues that dominate the interaction between NS3 and NS4A, and furth

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24

MacLellan, James Darcy. "Effects of the mitochondrial uncoupling protein 3 on fuel substrate oxidation and reactive oxygen species formation in rat L6 muscle cells." Thesis, University of Ottawa (Canada), 2007. http://hdl.handle.net/10393/27533.

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Uncoupling protein 3 (UCP3) is an integral mitochondrial membrane protein thought to disassociate fuel substrate oxidation by allowing proton re-entry into the mitochondrial matrix. Expression of UCP3 has been correlated with fatty acid and glucose metabolism, and reactive oxygen species (ROS) formation. To improve our understanding of the potential involvement of UCP3 in such pathways we investigated the effects of a UCP3 overexpression (2.2-2.5 fold) in the L6 muscle cell line. These findings were compared to those of UCP2 overexpression and DNP exposure. Palmitate oxidation was significantl

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25

Thérier, Julien. "Régulation de la voie des Mitogen-Activated Protein Kinase ERK1/2 par la phospholipase C gamma dans le signal du Macrophage-Colony Stimulating Factor." Lyon 1, 2005. http://www.theses.fr/2005LYO10121.

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Le M-CSF régule l'établissement du lignage monocytaire/macrophagique en assurant la survie, la prolifération mais aussi la différenciation des progéniteurs myéloïdes en cellules très spécialisées : les macrophages. Ce contrôle nécessite la transduction d'un signal intracellulaire impliquant de nombreuses molécules. Parmi celles-ci, les MAPK ERK1/2 présentent une cinétique d'activation caractéristique : une première vague de phosphorylation rapide et transitoire puis une seconde vague tardive et soutenue essentielle à la différenciation macrophagique. J'ai montré au cours de cette étude que la

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26

Zechner, Kerstin. "3' end processing and RNA polymerase II transcription termination in protein coding genes in the nematode C. elegans." Thesis, University of Oxford, 2011. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.564397.

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In all organisms studied so far, the recognition of a functional poly(A) site is essential for RNA polymerase II termination at the end of nearly all genes transcribed by this enzyme (Whitelaw and Proudfoot, 1986; Guo et al., 1995; Birse et al. 1997). A number of eukaryotes have some of their genes organised in polycistronic structures which resemble bacterial operons (Davis and Hodgson, 1997; Ganot et al., 2004; Spieth et al. 1993), and in C. elegans, approximately 20% of all genes are contained within these operon-like structures (Blumenthal et al., 2002). Here, functional poly(A) sites will

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27

Yasmin, Lubna. "Exoenzyme S of Pseudomonas aeruginosa : cellular targets and interaction with 14-3-3." Doctoral thesis, Umeå : Univ, 2007. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-1411.

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28

Dettori, Rosalia Angela [Verfasser], and Albrecht [Akademischer Betreuer] Piiper. "Regulation of the interaction between protein kinase C-related protein kinase 2 (PRK2) and its upstream kinase, 3-phosphoinositide-dependent protein kinase 1 (PDK1) / Rosalia Angela Dettori. Betreuer: Albrecht Piiper." Saarbrücken : Saarländische Universitäts- und Landesbibliothek, 2011. http://d-nb.info/1051285267/34.

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Dettori, Rosalia Angela [Verfasser], and Albrecht [Akademischer Betreuer] Piiper. "Regulation of the interaction between protein kinase C-related protein kinase 2(PRK2) and its upstream kinase, 3-phosphoinositide-dependent protein kinase 1 (PDK1) / Rosalia Angela Dettori ; Betreuer: Albrecht Piiper." Saarbrücken : Saarländische Universitäts- und Landesbibliothek, 2017. http://d-nb.info/1131628934/34.

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30

Marignani, Paola A. "Effects of omega3-polyunsaturated fatty acids on the formation of sn-1,2-diradylglycerol, cytokine secretion and the regulation of protein kinase C activity." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1997. http://www.collectionscanada.ca/obj/s4/f2/dsk2/tape16/PQDD_0025/NQ30157.pdf.

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31

Eriksson, Therese. "Organelle movement in melanophores: Effects of Panax ginseng, ginsenosides and quercetin." Licentiate thesis, Linköpings universitet, Farmakologi, 2009. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-19973.

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Panax ginseng is a traditional herb that has been used for over 2000 years to promote health and longevity. Active components of ginseng include ginsenosides, polysaccharides, flavonoids, polyacetylenes, peptides, vitamins, phenols and enzymes, of which the ginsenosides are considered to be the major bioactive constituents. Although widely used, the exact mechanisms of ginseng and its compounds remain unclear. In this thesis we use melanophores from Xenopus laevis to investigate the effects of Panax ginseng extract G115 and its constituents on organelle transport and signalling. Due to coordin

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32

Meßmer, Andreas Thomas [Verfasser], Jens [Akademischer Betreuer] Bredenbeck, and Josef [Akademischer Betreuer] Wachtveitl. "Shedding light on reaction mechanisms : structure determination of reactive intermediates and investigation of protein structural dynamics using 2D-IR spectroscopy / Andreas T. Meßmer. Gutachter: Jens Bredenbeck ; Josef Wachtveitl. Betreuer: Jens Bredenbeck." Frankfurt am Main : Univ.-Bibliothek Frankfurt am Main, 2013. http://nbn-resolving.de/urn:nbn:de:hebis:30:3-293750.

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33

Lo, Kin Ho. "Activation of signal transducer and activator of transcription 3 (STAT3) by G[alpha]16 and G[alpha]14 via a c-Src/JAK-and ERK-dependent mechanism /." View abstract or full-text, 2004. http://library.ust.hk/cgi/db/thesis.pl?BICH%202004%20LO.

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Thesis (M. Phil.)--Hong Kong University of Science and Technology, 2004.<br>Includes bibliographical references (leaves 92-111). Also available in electronic version. Access restricted to campus users.

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34

Lemos, Marcos Alexandre Nobre. "Expressão gênica da proteína não estrutural 3 do vírus da hepatite C empregando pseudopartículas virais." Universidade de São Paulo, 2014. http://www.teses.usp.br/teses/disponiveis/87/87131/tde-08122014-143251/.

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A hepatite viral causada pelo vírus da hepatite C (HCV) é um problema à saúde mundial e afeta cerca de 170 milhões de pessoas. O caso crônico da doença resulta em cirrose hepática e a maioria dos pacientes tratados não desenvolve uma resposta imune satisfatória. A proteína não estrutural 3 (NS3) pode estimular uma resposta celular que auxilia a resposta nos infectados. Nosso trabalho desenvolveu duas pseudopartículas virais que carregam um material genético para a protease da NS3 do HCV. Um dos sistemas, a HCVpp é constituída por proteínas do vírus da leucemia murina e outras do HCV. E o outro

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35

Albarqi, Mennatallah M. Y. "INSIGHTS INTO HOW THE 3´UTR MEDIATES EXPRESSION OF A CONSERVED RNA-BINDING PROTEIN AND CONTRIBUTES TO GERMLINE DEVELOPMENT IN C. ELEGANS." eScholarship@UMMS, 2021. https://escholarship.umassmed.edu/gsbs_diss/1156.

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Maternal mRNA regulation is essential to germline and embryo development in metazoans. Over the past few decades, it has become clear that many RNA-binding proteins (RBPs) containing highly conserved RNA-binding domains orchestrate spatiotemporal expression pattern of germline and embryonic genes to control gametogenesis and embryogenesis in the nematode Caenorhabditis elegans. These RBPs bind regulatory elements situated primarily in the UTRs of their target mRNAs to regulate expression by influencing transcript stability or translational efficiency. The 3´UTR is the main determinant of patte

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36

O'Donnell, Joshua D. "BRCA1 185delAG Mutant Protein, BRAt, Amplifies Caspase-Mediated Apoptosis and Maspin Expression in Ovarian Cells." [Tampa, Fla] : University of South Florida, 2008. http://purl.fcla.edu/usf/dc/et/SFE0002422.

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Kim, Young B. "Heteroatom insertion reactions of metal carbenoids : synthesis and biological evaluation for protein kinase C. /." Full text available from ProQuest UM Digital Dissertations, 2008. http://0-proquest.umi.com.umiss.lib.olemiss.edu/pqdweb?index=0&did=1836404551&SrchMode=1&sid=3&Fmt=2&VInst=PROD&VType=PQD&RQT=309&VName=PQD&TS=1258562682&clientId=22256.

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Thesis (Ph.D.)--University of Mississippi, 2008.<br>Typescript. Vita. Major professor: Dr. John M. Rimoldi "November 2008." Includes bibliographical references (leaves 114-136). Also available online via ProQuest to authorized users.

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Dünnes, Nadia [Verfasser]. "Analyse der Interaktion von microRNA-122-Protein-Komplexen mit der NS5B-kodierenden Region und der 3´-untranslatierten Region der Hepatitis C Virus-RNA / Nadia Dünnes." Gießen : Universitätsbibliothek, 2016. http://d-nb.info/1118289773/34.

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Franz, Steffen. "Die Bedeutung von CCAAT/Enhancer Binding Protein (C/EBP) beta und Suppressor of Cytokine Signalling (SOCS) 1 & 3 für die Pathogenese der Amyotrophen Lateralsklerose (ALS)." Diss., lmu, 2007. http://nbn-resolving.de/urn:nbn:de:bvb:19-75566.

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Cederberg, Jonas. "Oxidative stress, antioxidative defence and outcome of gestation in experimental diabetic pregnancy." Doctoral thesis, Uppsala : Acta Universitatis Upsaliensis : Univ.-bibl. [distributör], 2001. http://publications.uu.se/theses/91-554-4960-3/.

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Meyer, Lucas Joachim [Verfasser], and Albrecht [Akademischer Betreuer] Piiper. "Role of the Z-/turn motif and of the N-Terminus of PRK2 in the regulation of the interaction between protein kinase C-related protein kinase 2 (PRK2) and 3-phosphoinositide dependent protein kinase 1 (PDK1) / Lucas Joachim Meyer. Betreuer: Albrecht Piiper." Saarbrücken : Saarländische Universitäts- und Landesbibliothek, 2011. http://d-nb.info/1051405491/34.

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Schneider, Elisabeth V. [Verfasser], Robert [Akademischer Betreuer] Huber, and Adelbert [Akademischer Betreuer] Bacher. "Structural and functional characterization of human protein kinases exemplified on the human cyclin-dependent kinase 8, cyclin C complex / Elisabeth Veronika Schneider. Gutachter: Robert Huber ; Adelbert Bacher. Betreuer: Robert Huber." München : Universitätsbibliothek der TU München, 2012. http://nbn-resolving.de/urn:nbn:de:bvb:91-diss-20120920-1108725-0-3.

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Nilsson, Lisa O. "Redesign of Alpha Class Glutathione Transferases to Study Their Catalytic Properties." Doctoral thesis, Uppsala : Acta Universitatis Upsaliensis : Univ.-bibl. [distributör], 2001. http://publications.uu.se/theses/91-554-5171-3/.

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Giblin, Sean. "Investigating cell lineage specific biosynthesis of tenascin-C during inflammation." Thesis, University of Oxford, 2018. http://ora.ox.ac.uk/objects/uuid:8c7306d8-53cf-4131-a134-f74885e37cc9.

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The extracellular matrix (ECM) is a complex network of molecules secreted by cells, which is essential for providing structural support and facilitating cell processes including adhesion, migration and survival. Tenascin-C is an immunomodulatory ECM protein that exhibits limited expression in healthy tissues, but is transiently elevated at sites of tissue injury, and is persistently expressed in chronic inflammatory diseases and tumours. Alternative splicing of 9 of tenascin-C's fibronectin type III-like domains (FnIII- A1, A2, A3, A4, B, AD2, AD1, C and D) generates enormous diversity in form

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Said, Rose. "Caractérisation des propriétés pro- et anti-coagulantes associées aux cellules musculaires lisses vasculaires." Thesis, Université de Lorraine, 2012. http://www.theses.fr/2012LORR0004/document.

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L'objectif principal de ce travail était de comparer l'implication (i) de cellules vasculaires, cellules musculaires lisses vasculaires (CML) et cellules endothéliales (CE), ou des cellules circulantes, les plaquettes, et (ii) des microparticules (MP) issues de ces différentes cellules dans la génération de la thrombine mais également dans son inhibition par les systèmes anticoagulants de la protéine C activée (PCa) et de l'inhibiteur de la voie du facteur tissulaire (TFPI), et d'identifier les mécanismes et les déterminants responsables des différences observées entre ces supports cellulaires

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46

Hallatschek, Werner. "Die Regulation des humanen Lipopolysaccharid bindenden Proteins (hLBP)." Doctoral thesis, Humboldt-Universität zu Berlin, Mathematisch-Naturwissenschaftliche Fakultät I, 2005. http://dx.doi.org/10.18452/15202.

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Das Lipopolysaccharid Bindende Protein (LBP) ist ein überwiegend in der Leber synthetisiertes Akutphaseprotein. Es bindet den Zellwandbestandteil Lipopolysaccharid (LPS) Gram-negativer Bakterien und transportiert es zu zellulären Rezeptoren, wodurch das angeborene Immunsystem aktiviert wird. In dieser Arbeit wird die Regulation der LBP-Expression in Interleukin (IL)-1, IL-6 und Dexamethason (Dex) stimulierten humanen Hepatomzelllinien HuH-7 und HepG2 untersucht. Der wichtigste Stimulator ist dabei IL-6, dessen Wirkung über die Transkriptionsfaktoren (TF) Stat-3, C/EBP-beta und AP-1 vermittel

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47

Briggs, Matthew S. "Obesity-Associated Morbidities in Children and Adolescents: The Correlates Between Knee Biomechanics, Musculoskeletal Impairments, Limitations in Health Related Quality of Life, and Cardiovascular Risk." The Ohio State University, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=osu1397488659.

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48

Patiño, Sandra Fernanda Suárez. "Produção de proteínas recombinantes em células BHK-21 cultivadas em meio livre de soro fetal bovino." Universidade de São Paulo, 2016. http://www.teses.usp.br/teses/disponiveis/87/87131/tde-25082016-145258/.

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Abstract:

Células eucariotas usadas como plataforma de expressão de proteínas recombinantes são geralmente cultivadas com soro fetal bovino (SFB), porém, abordagens biotecnológicas atuais sobre cultura de células devem evitar o uso deste suplemento, devido a problemas de custo, variações entre os lotes e risco de contaminação. Assim, nosso objetivo foi expressar as proteínas recombinantes: GFP (proteína verde fluorescente), NS3 (proteína não estrutural 3 do vírus da hepatite C) e RVGP (glicoproteína do vírus da raiva) em células BHK-21 adaptadas em meios livres de soro fetal bovino (SFM) usando o sistem

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49

Omar, Hany Ahmed Mostafa Mohamed. "Molecular Pharmacology and Preclinical Studies of Novel Small-molecule Targeted Agents for The Treatment of Hepatocellular Carcinoma." The Ohio State University, 2010. http://rave.ohiolink.edu/etdc/view?acc_num=osu1290565602.

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50

Suzuma, Izumi. "Stretch-induced retinal vascular endothelial growth factor expression is mediated by phosphatidylinositol 3-kinase and protein kinase c (PKC)-ζ but not by stretch-induced ERK1/2, Akt, Ras, or classical/novel PKC pathways". Kyoto University, 2004. http://hdl.handle.net/2433/147489.

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