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Journal articles on the topic 'Omega-3 and C-reactive protein-hs'

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Published: 4 June 2021

Last updated: 1 February 2022

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1

Savitri, Nadia, and Niken Puruhita. "PENGARUH PEMBERIAN IKAN TERI (Engraulis encrasicolus) TERHADAP KADAR C-REACTIVE PROTEIN (CRP) TIKUS SPRAGUE DAWLEY USIA SATU BULAN." Journal of Nutrition College 3, no. 4 (2014): 966–71. http://dx.doi.org/10.14710/jnc.v3i4.6918.

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Latar Belakang: C-reactive protein (CRP), adalah marker inflamasi yang merupakan prediktor kuat kejadian penyakit kardiovaskuler (PKV). Peningkatan kadar CRP berkaitan dengan peningkatan risiko PKV. Asam lemak omega-3 diketahui memiliki sifat-sifat anti inflamasi sehingga asam lemak omega-3 dipercaya memiliki efek protektif terhadap PKV. CRP juga berkaitan dengan indeks omega-3 sebagai prediktor asupan omega-3. Kadar indeks omega-3 yang rendah diketahui meningkatkan risiko PKV. Ikan teri (Engraulis encrasicolus) mengandung asam lemak omega-3 yang tinggi yang dimungkinkan dapat menurunkan kadar

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Jafari Salim, Shirin, Shahab Alizadeh, Mahmoud Djalali, Ebrahim Nematipour, and Mohammad Hassan Javanbakht. "Effect of Omega-3 Polyunsaturated Fatty Acids Supplementation on Body Composition and Circulating Levels of Follistatin-Like 1 in Males With Coronary Artery Disease: A Randomized Double-Blind Clinical Trial." American Journal of Men's Health 11, no. 6 (2017): 1758–64. http://dx.doi.org/10.1177/1557988317720581.

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Adipokines are mediators of body composition and are involved in obesity-related complications such as cardiovascular disease. Omega-3 supplementation has not been studied in the setting of body composition and follistatin-like 1 (FSTL1) levels in patients with coronary artery disease (CAD). This study aimed to investigate the effect of omega-3 polyunsaturated fatty acid (ω-3 PUFA) supplementation on body composition indices and serum levels of FSTL1 in CAD patients. A total of 42 male (aged 45–65 years) subjects with angiographically confirmed CAD were included in this randomized, double-blin

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Mohammadi Sartang, Mohsen, Seyed Mohammad Mazloomi, Nader Tanideh, and Abbas Rezaian Zadeh. "The Effects of Probiotic Soymilk Fortified with Omega-3 on Blood Glucose, Lipid Profile, Haematological and Oxidative Stress, and Inflammatory Parameters in Streptozotocin Nicotinamide-Induced Diabetic Rats." Journal of Diabetes Research 2015 (2015): 1–9. http://dx.doi.org/10.1155/2015/696372.

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Objective. The aim of the present study was to evaluate the effects of probiotic soymilk fortified with omega-3 in diabetic rats.Methods. Soymilk (SM), fermented soymilk (FSM), and fermented soymilk fortified with omega-3 (FSM + omega-3) were prepared. Rats were randomly assigned to five groups of 13 animals per group. Diabetes was induced by a single injection of streptozotocin (STZ) 15 min after the intraperitoneal administration of nicotinamide (NA). Normal control (NC) and diabetic control (DC) rats received 1 mL/day of distilled water and three groups of diabetic rats were given 1 mL/day

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Sellner, J., I. Greeve, and HP Mattle. "Atorvastatin decreases high-sensitivity C-reactive protein in multiple sclerosis." Multiple Sclerosis Journal 14, no. 7 (2008): 981–84. http://dx.doi.org/10.1177/1352458508091368.

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The anti-inflammatory potential of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors, as reflected by modulation of C-reactive protein (CRP), might be beneficial in the treatment of patients with multiple sclerosis (MS). We evaluated serum levels of high-sensitivity (hs)-CRP in relapsing–remitting MS patients receiving interferon-β 1b and atorvastatin as add-on therapy. This study shows that interferon-β treatment is associated with increased serum levels of hs-CRP in MS patients ( P < 0.01). In contrast, when atorvastatin is added to interferon-β, hs-CRP serum levels decrease to t

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Wilson, Wilson, Eka Agustia Rini, and Hafni Bachtiar. "Pengaruh Pemberian Omega-3 Terhadap Kadar C-Reactive Protein pada Remaja Obes Resistensi Insulin." Sari Pediatri 17, no. 1 (2016): 41. http://dx.doi.org/10.14238/sp17.1.2015.41-6.

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Latar belakang. Obesitas berperan penting terhadap terjadinya sindrom metabolik yang dapat menyebabkan resistensi insulin,dislipidemia, diabetes mellitus dan hipertensi yang akan meningkatkan risiko penyakit jantung koroner. Jaringan adiposa padaobesitas akan memproduksi berbagai sitokin antara lain TNF-α dan IL-6 yang selanjutnya merangsang hati untuk menghasilkanC-RP. Omega-3 mempunyai efek anti inflamasi, dapat meningkatkan sensitifitas insulin, mengurangi resistensi insulin, perlemakanhati dan memperbaiki profil lemak serta menurunkan kadar C-RP.Tujuan. Mengetahui pengaruh pemberian Omega-

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Camardese, G., G. Pizi, B. Leone, et al. "Somatic symptoms and high-sensitive C-reactive protein in major depression." European Psychiatry 26, S2 (2011): 615. http://dx.doi.org/10.1016/s0924-9338(11)72322-7.

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AimHigh-sensitive C-reactive protein (hs-CRP) has been used to assess low-grade immune system activation. In a population-based cohort hs-CRP was associated with functional somatic symptoms (SS), particularly with general and musculoskeletal functional SS clusters.Immune system dysregulation has also been reported in depression that is frequently associated to a high burden of SS.We investigated the correlation between hs-PCR and SS in depressed patients.Methods123 outpatients (M/F = 58/65; mean age 48,6 ± 14,8) during a Major Depressive Episode were recruited at the Institute of Psychiatry of

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Mirmasoumi, Golara, Mohammad Fazilati, Fatemeh Foroozanfard, et al. "The Effects of Flaxseed Oil Omega-3 Fatty Acids Supplementation on Metabolic Status of Patients with Polycystic Ovary Syndrome: A Randomized, Double-Blind, Placebo-Controlled Trial." Experimental and Clinical Endocrinology & Diabetes 126, no. 04 (2017): 222–28. http://dx.doi.org/10.1055/s-0043-119751.

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Abstract Objective This study was conducted to evaluate the effects of flaxseed oil omega-3 fatty acids supplementation on metabolic status of patients with polycystic ovary syndrome (PCOS). Methods This randomized double-blind, placebo-controlled trial was conducted on 60 women with PCOS according to the Rotterdam criteria aged 18–40 years old. Participants were randomly assigned into two groups to receive either 1,000 mg flaxseed oil omega-3 fatty acids (n=30) or placebo (n=30) twice a day for 12 weeks. Metabolic, endocrine, inflammatory factors were quantified at baseline and after the 12-w

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Gao, Jingli, Aitian Wang, Xiaolan Li, et al. "The Cumulative Exposure to High-Sensitivity C-Reactive Protein Predicts the Risk of Chronic Kidney Diseases." Kidney and Blood Pressure Research 45, no. 1 (2019): 84–94. http://dx.doi.org/10.1159/000504251.

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Background and Objectives: This study was to characterize the association of cumulative exposure to increased high-sensitivity C-reactive protein (hs-CRP) with chronic kidney diseases (CKD). Methods: We included 35,194 participants with hs-CRP measured at three examinations in 2006, 2008, 2010. Participants were classiﬁed into nonexposed group (hs-CRP <3.0 mg/L in all 3 examinations), 1-exposed group (hs-CRP ≥3.0 mg/L in 1 of the 3 examinations), 2-exposed group (hs-CRP ≥3.0 mg/L in 2 of the 3 examinations), and 3-exposed group (hs-CRP ≥3.0 mg/L in 3 examinations). Cox proportional hazards

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Rothkrantz-Kos, Snjezana, Otto Bekers, Armand Gubbels, Marjolein Drent, Maria P. J. Schmitz, and Marja P. van Dieijen-Visser. "Evaluation of two new high-sensitivity methods for C-reactive protein." Annals of Clinical Biochemistry: International Journal of Laboratory Medicine 40, no. 4 (2003): 398–405. http://dx.doi.org/10.1258/000456303766477057.

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Background: The implementation of a high-sensitivity C-reactive protein (hs-CRP) assay as a routine laboratory parameter may be necessary. It would be most practical to use one CRP method giving reliable results for the whole concentration range. We report here the evaluation of two new hs-CRP methods, which cover both the low and the high concentration ranges. Methods: The BN ProSpec hs-CRP (Dade Behring) and Synchron LX 201 PRO hs-CRP methods were compared with the existing hs-CRP IMMAGE1 method (taken as a reference) and, for the high concentration range, also with the routine Synchron LX1

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Putri, Tissi Liskawini, Ratna Akbari Ganie, and Aldy S. Rambe. "NEUTROPHIL-LYMPHOCYTE RATIO AND HIGH SENSITIVITY C-REACTIVE PROTEIN AS ISCHEMIC STROKE OUTCOME PREDICTOR (Rasio Neutrofil–Limfosit dan High Sensitivity C–Reactive Protein sebagai Peramal Hasilan Strok Iskemik Akut)." INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY 23, no. 3 (2018): 240. http://dx.doi.org/10.24293/ijcpml.v23i3.1201.

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Proses inflamasi merupakan perjalanan penyakit dari strok iskemik akut, yang melibatkan penumpukan mediator inflamasi daninfiltrasi leukosit. Nilai Rasio Neutrofil-Limfosit (RNL) di beberapa penelitian dapat digunakan untuk meramalkan strok akibat iskemikakut yang caranya mudah dilakukan. High sensitivity C Reactive Protein (hs-CRP) merupakan reaktan tahap akut yang kadarnyameningkat di strok iskemik. Oleh karena itu bermanfaat sebagai petanda peramal hal terkait. Penelitian ini bertujuan untuk mengetahuiperbedaan nilai antara RNL dan hs-CRP dalam meramalkan hasilan pasien strok iskemik akut.

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Meena, Priyanka, Sourabh Goswami, Ajay Mathur, and Ramji Sharma. "A study of high sensitive C-reactive protein in rheumatoid arthritis patients." International Journal of Research in Medical Sciences 9, no. 1 (2020): 139. http://dx.doi.org/10.18203/2320-6012.ijrms20205832.

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Background: Rheumatoid arthritis (RA) is not only merely limited to joints but has many extraarticular features. The major cause of mortality in RA is cardiovascular disease (CVD). Inflammation in RA predispose them to succumb to CVD. The aim of this study to observe whether therapy with disease-modifying anti-rheumatic drugs (DMARD) decreases inflammation and if it does so than it can be said that decrease the risk to develop CVD. Aim and objectives were to assess hs-CRP level in early and established RA both at diagnosis and again at 3 months of DMARD therapy and compare between them.Methods

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Boch, Samantha J., and Jodi L. Ford. "C-Reactive Protein Levels Among U.S. Adults Exposed to Parental Incarceration." Biological Research For Nursing 17, no. 5 (2014): 574–84. http://dx.doi.org/10.1177/1099800414564011.

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Previous studies have linked childhood adversity to low-grade inflammation via C-reactive protein (CRP) levels. This study analyzed the association between low-grade inflammation and prior biological parental incarceration. Data from the National Longitudinal Study of Adolescent to Adult Health (1994–2008) were analyzed using multinomial logistic regression models. Measures included high-sensitivity (hs)-CRP (<3 mg/L = reference, 3–10 mg/L = low-grade inflammation, and >10 mg/L = acute inflammation), parent incarceration occurring in the child’s lifetime, and frequency and timing of inca

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Zheng, Fanfan, and Wuxiang Xie. "High-sensitivity C-reactive protein and cognitive decline: the English Longitudinal Study of Ageing." Psychological Medicine 48, no. 8 (2017): 1381–89. http://dx.doi.org/10.1017/s0033291717003130.

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AbstractBackgroundHigh-sensitivity C-reactive protein (hs-CRP) has been suggested to be involved in the process of cognitive decline. However, the results from previous studies exploring the relationship between hs-CRP concentration and cognitive decline are inconsistent.MethodWe employed data from wave 2 (2004–2005) to wave 7 (2014–2015) of the English Longitudinal Study of Ageing. Cognitive function was assessed at baseline (wave 2) and reassessed biennially at waves 3–7.ResultsA total of 5257 participants (54.9% women, mean age 65.4 ± 9.4 years) with baseline hs-CRP levels ranged from 0.2 t

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Liu, Lili, Bixia Gao, Jinwei Wang, et al. "Reduction in Serum High-Sensitivity C-Reactive Protein Favors Kidney Outcomes in Patients with Impaired Fasting Glucose or Diabetes." Journal of Diabetes Research 2020 (June 10, 2020): 1–7. http://dx.doi.org/10.1155/2020/2720905.

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Objective. We aimed to evaluate whether the reduction in serum high-sensitivity C-reactive protein (hs-CRP) favors kidney outcomes. Methods. This study was a subanalysis including patients with impaired fasting glucose or diabetes of the Kailuan cohort study. The predictor was based on two consecutive visits of hs-CRP levels in 2006 and 2008. A total of 3924 patients with hs-CRP≥3 mg/L in 2006 were divided into two groups according to whether the levels of hs-CRP were reduced in 2008: Group 1: no reduction: hs-CRP≥3 mg/L in 2008; Group 2: reduction: hs-CRP<3 mg/L in 2008. Kidney outcomes in

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Wiradarma, Karin, Diana Sunardi, and Ninik Mudjihartini. "Correlation between Serum Hugh Sensitivity C-Reactive Protein With Dietary Intake of Indonesian Lactating Mothers." World Nutrition Journal 3, no. 1 (2019): 27. http://dx.doi.org/10.25220/wnj.v03.i1.0008.

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Background and Objectives:Chronic low-grade inflammation has emerged as important pathophysiology of non-communicable diseases, which can cause negative effects to mother and baby. Dietary intake has been known as important factor to affect inflammation, which can be measured by high-sensitivity C-reactive protein (hs-CRP). This study aimed to examine the correlation between serum hs-CRP with dietary intake in lactating mothers.Methods:A cross-sectional study was conducted by consecutively enrolling 71 lactating mothers, 3-6 months post-partum, age 20-35 years old, visiting Grogol Petamburan a

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Thaha, Mochammad, Tri Asih Imroati, Aditia Wardana, S. Widodo, S. Pranawa, and Chandra Irwanadi. "Comparison of High-sensitivity C-reactive Protein Level between Chronic Kidney Disease Stages." Biomolecular and Health Science Journal 1, no. 1 (2018): 1. http://dx.doi.org/10.20473/bhsj.v1i1.8226.

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ABSTRACTAim : This research is to evaluate the hs-CRP level comparison between CKD stages in Dr. Soetomo General Hospital Surabaya.Methods: An analytic observational cross-sectional study, evaluating the differences of hs-CRP level between CKD stages in 72 patients (mean age 55.49±7.62 years, the ratio between male:female was 1:1.48, mean BMI 24.18±3.64 kg/m2, 36.11% diabetics, 43.05% on ACEI/ARB, 29.16% on statin), recruited from Nephrology Outpatient Clinic, Dr Soetomo General Hospital, Surabaya, from January to May 2014. The stages were stratified according to the MDRD formula.Results: The

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Kalva-Borato, Danielle C., Josilaine Tonin Ribas, Gisele Chibinski Parabocz, et al. "Biomarkers in Non-Complicated Pregnancy: Insights About Serum Myeloperoxidase and Ultrasensitive C-Reactive Protein." Experimental and Clinical Endocrinology & Diabetes 127, no. 09 (2018): 585–89. http://dx.doi.org/10.1055/a-0777-2090.

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Abstract Introduction Pregnancy is characterized by increased innate immune response, with low-grade systemic inflammation. The specific role of MPO during normal pregnancy remains not well understood. Therefore, the aim of this study was to evaluate plasma levels of MPO, hs-CRP, total leukocyte, absolute neutrophil and monocyte counts, in all trimesters of normal human pregnancy compared with non-pregnant controls. In addition, possible fluctuations of MPO according to different inflammatory conditions in the normal gestation were studied. Materials and methods Case-control study (n=84) devel

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Rukmi, Dyah Anetta Afri, and Joseph Eko Wahono Rahardjo. "Correlation Between High Sensitivity C-Reactive Protein Level and Executive Function Disorders in Elderly Patients." Journal of Computational and Theoretical Nanoscience 17, no. 7 (2020): 3113–16. http://dx.doi.org/10.1166/jctn.2020.9145.

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C-Reactive Protein is a marker of inflammation and vascular disease. The high serum of high-sensitivity C-Reactive Protein (hs-CRP) concentration was associated with interruption the integrity of the frontal-subcortical circuit. To determine the correlation between high serum concentration of hs-CRP and executive function disorder in elderly patients. Thirty six elderly patients was examined by using a case control study. The subjects were enrolled from the out-patient at Neurology Department Dr. Soetomo General Hospital, Surabaya, Indonesia. The time period was 4 months (April to July 2015).

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Liu, Tong, Sarah Tan Siyin, Nan Yao, et al. "Relationship between high-sensitivity C reactive protein and the risk of gallstone disease: results from the Kailuan cohort study." BMJ Open 10, no. 9 (2020): e035880. http://dx.doi.org/10.1136/bmjopen-2019-035880.

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ObjectivesGallstone disease (GSD) can be caused by various health and clinical factors such as obesity, dyslipidaemia and an unhealthy diet, all of which are associated with higher high-sensitivity C reactive protein (hs-CRP) concentrations. Whether hs-CRP represents an independent risk factor for GSD is still unclear. We prospectively investigated hs-CRP in relation to the occurrence of GSD based on the Kailuan study.Study designProspective cohort study.SettingThe Kailuan cohort study was conducted in Tangshan City in northern China.Participants95 319 participants who were free from GSD were

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Zeba, Augustin N., Hélène F. Delisle, Clémentine Rossier, and Genevieve Renier. "Association of high-sensitivity C-reactive protein with cardiometabolic risk factors and micronutrient deficiencies in adults of Ouagadougou, Burkina Faso." British Journal of Nutrition 109, no. 7 (2012): 1266–75. http://dx.doi.org/10.1017/s0007114512003182.

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Increasing evidence suggests that high-sensitivity C-reactive protein (hs-CRP) is associated with cardiometabolic risk factors (CMRF) while being also related to micronutrient deficiencies. As part of a project on the double burden of under- and overnutrition in sub-Saharan Africa, we assessed the relationship between hs-CRP and both CMRF and micronutrient deficiencies in a population-based cross-sectional study carried out in the Northern district of Ouagadougou, the capital city of Burkina Faso. We randomly selected 330 households stratified by income tertile. In each income stratum, 110 ind

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Naramura, Tetsuo, Hiroko Imamura, Hidetaka Yoshimatsu, et al. "The Predictive Value of Procalcitonin and High-Sensitivity C-Reactive Protein for Early Bacterial Infections in Preterm Neonates." Neonatology 118, no. 1 (2020): 28–36. http://dx.doi.org/10.1159/000512523.

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<b><i>Introduction:</i></b> Evidence on the reliability of using procalcitonin (PCT) and high-sensitivity C-reactive protein (hs-CRP) as diagnostic markers for early-onset neonatal bacterial infections is still insufficient because of their physiological elevation during the early neonatal period. This study aimed to assess the respiratory influence of serum PCT and hs-CRP levels and evaluate their predictive value for bacterial infections during the first 72 h of life in preterm neonates. <b><i>Methods:</i></b> The preterm neonates enrolled in t

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Azam, Mahalul, Susanti Lestari, Sri Ratna Rahayu, et al. "Baseline and Post-exercise High-Sensitivity C-Reactive Protein Levels in Endurance Cyclists: The Indonesian North Coast and Tour de Borobudur 2017 Study." Indonesian Biomedical Journal 11, no. 1 (2019): 91–9. http://dx.doi.org/10.18585/inabj.v11i1.560.

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BACKGROUND: Inflammation plays an important role in the atherosclerotic process. High-sensitivity C-reactive-protein (hs-CRP) is commonly used as inflammatory biomarker. It is well known that regular physical activity lowers hs-CRP levels, while prolonged exercise induces hs-CRP elevations. However, the relationship of training and exercise characteristics with hs-CRP levels remains not well elucidated. We evaluated baseline and post-exercise hs-CRP levels and its association with training and exercise characteristics.METHODS: Eighty-eight male endurance cyclists were involved. Demographic dat

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Puspitadewi, Irene Nucifera, Ani Margawati, and Hartanti Sandi Wijayanti. "Pengaruh Pemberian Sari Ubi Ungu (Ipomea batatas L.) Terhadap KadarHigh Sensitivity C-Reactive Protein(hs-CRP) Pada Tikus Sprague Dawley Dengan Pakan Tinggi Lemak." Journal of Nutrition College 7, no. 4 (2018): 155. http://dx.doi.org/10.14710/jnc.v7i4.22274.

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Latar Belakang: Komposisi makanan tinggi lemak dapat menjadi faktor terjadinya obesitasyang menyebabkan oksidasi lemak. Oksidasi lemak dapat menyebabkan inflamasi yang dikarakterisasikan dengan tingginya kadar High Sensitivity C-Reactive Protein (hs-CRP). Ubi ungu kaya akan antioksidan terutama antosianin yang mungkin dapat menurunkan kadar hs-CRP. Penelitian ini bertujuan untuk mengetahui pengaruh sari ubi ungu terhadap kadar hs-CRP tikus sprague dawley dengan pakan tinggi lemak.Metode: Jenis penelitian ini adalah true experimental dengan pre-post test control group design. 24 tikus sprague d

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Priyanka, N., Minal Kumari, Nitish Kalra, P. Arjun, Savitha B. Naik, and A. R. Pradeep. "Crevicular Fluid and Serum Concentrations of Progranulin and High Sensitivity CRP in Chronic Periodontitis and Type 2 Diabetes." Disease Markers 35 (2013): 389–94. http://dx.doi.org/10.1155/2013/803240.

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Introduction. This study was designed to correlate the serum and gingival crevicular fluid (GCF) levels of progranulin (PGRN) and high sensitivity C-reactive protein (hs CRP) in chronic periodontitis and type 2 diabetes mellitus (DM).Design. PGRN and hs CRP levels were estimated in 3 groups: healthy, chronic periodontitis, and type 2 DM with chronic periodontitis.Results. The mean PGRN and hs CRP concentrations in serum and GCF were the highest for group 3 followed by group 2 and the least in group 1.Conclusion. PGRN and hs CRP may be biomarkers of the inflammatory response in type 2 DM and ch

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Huang, Christina M., Michelle A. Lowes, Christine Cserti, and Afsaneh Alavi. "Hemoglobin Levels and Serum C-Reactive Protein in Patients With Moderate to Severe Hidradenitis Suppurativa." Journal of Cutaneous Medicine and Surgery 23, no. 5 (2019): 501–6. http://dx.doi.org/10.1177/1203475419858963.

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Introduction: Anemia of chronic inflammation is associated with many inflammatory diseases. Little is known about anemia in hidradenitis suppurativa (HS). This study aimed to review the levels of hemoglobin (Hb) and investigate its relationship with serum C-reactive protein (CRP) and disease severity in HS patients. Methods: This was a retrospective chart review of all HS patients from 2015 to 2017 with Hb and CRP blood work. Patient demographics, disease severity, and laboratory results were extracted. Data were analyzed descriptively. A linear regression model was used for the association be

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Barbui, Tiziano, Alessandra Carobbio, Barbara Bottazzi, et al. "High-Sensitivity C-Reactive Protein (hs-CRP) and Pentraxin 3 (PTX3) Are Increased in Essential Thrombocythemia and Polycythemia Vera." Blood 114, no. 22 (2009): 1911. http://dx.doi.org/10.1182/blood.v114.22.1911.1911.

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Abstract Abstract 1911 Poster Board I-934 Background: The role of inflammation in the pathogenesis of the athero-thrombosis has become well established over the past decade. In general population, markers of inflammation are associated with cardiovascular events and predictors of future thrombosis are leukocyte (WBC) count and short and long pentraxins such as high-sensitivity C-reactive protein (hs-CRP) and pentraxin 3 (PTX3). In Polycythemia Vera (PV) and Essential Thrombocythemia (ET), WBC count has been related to major vascular complications and there is evidence that this association can

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Kunal, Shekhar, Pradeep Kumar Meena, Pooja Pathak, Himanshu Mahla, Kashish Gupta, and Vijay Pathak. "High-sensitivity C-reactive protein and interleukin-6 as risk predictors in patients with stable angina pectoris." International Journal of Advances in Medicine 7, no. 9 (2020): 1322. http://dx.doi.org/10.18203/2349-3933.ijam20203594.

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Background: Cardiovascular diseases are a leading cause of morbidity and mortality especially in developing countries such as India. Biomarkers such as high-sensitivity C-reactive protein (Hs-CRP) and interleukin-6 (IL-6) can help in risk stratification and better management of patients with stable angina.Methods: This was a prospective observational study wherein symptomatic patients with stable angina were enrolled. Coronary angiogram was done in those consenting to the procedure. Severity of coronary stenosis was graded as per the modified Gensini score (mGS). Hs-CRP and IL-6 levels were de

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Rasmi, Y., M. H. Seyed-Mohammadzad, and S. Raeisi. "Relationship Between High Sensitivity C-reactive Protein and CagA Positive Helicobacter pylori in Cardiac Syndrome X." Journal of Scientific Research 5, no. 3 (2013): 527–33. http://dx.doi.org/10.3329/jsr.v5i3.14171.

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Cytotoxin-associated gene A (CagA) may induce a persistent systemic inflammatory response in cardiac syndrome X (CSX). We aimed to evaluate relationship of CagA status and high sensitivity C-reactive protein (hs-CRP) in CSX patients. Sixty CSX patients and 60 gender matched controls were enrolled. Plasma samples were tested in terms of the presence of IgG antibody to Helicobacterpylori (anti-H. pylori) and CagA (anti-CagA) using ELISA method. Also, plasma level of hs-CRP was measured by ELISA method. CSX patients were detected to have significantly higher plasma hs-CRP level in comparison with

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Sitepu, Nadroh Br, and Urip Harahap. "The Role Of hs-CRP In Predicting The Likelihood Of Coronary Heart Disease." Indonesian Journal of Pharmaceutical and Clinical Research 3, no. 1 (2020): 51–61. http://dx.doi.org/10.32734/idjpcr.v3i1.4015.

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Coronary Heart Disease (CHD) is a disorder of the cardiovascular system, characterized by atherosclerotic lesions. Inflammation is a strong predictor for coronary heart disease. High sensitivity C-Reactive Protein (hs-CRP) is an important biomarker, synthesized in the liver, can predict the severity of CHD. If the hs-CRP level is found to be low 3 mg / L, a person has the potential for severe vascular risk. Therefore, hs-CRP can be used as a predictor of primary CHD prevention, especially if the hs-CRP level is still low.

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Khunte, Sanjeev Kumar, Jitendra Kumar, and Prakash Khunte. "Role of high sensitivity C- reactive protein as a marker of inflammation and its prognostic significance in chronic kidney disease patients." International Journal of Advances in Medicine 6, no. 2 (2019): 335. http://dx.doi.org/10.18203/2349-3933.ijam20191137.

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Background: Chronic kidney disease (CKD) is a clinical syndrome due to irreversible renal dysfunction leading to excretory, metabolic and synthetic failure culminating into accumulation of non-protein nitrogenous substances and present with various clinical manifestations. Elevated circulating concentrations of CRP are a common phenomenon in ESRD patients. The prevalence and magnitude of inﬂammation increases as renal function declines.Methods: The current cross-sectional observation study was conducted in Rajendra institute of medical sciences, Ranchi during study period October 2015 to Septe

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D, Dayanand C., Vanishree Bambrana, and Sheela Sr. "PHOSPHOLIPASE A 2 , PLASMA ELASTASE ACTIVITY IN PRE- AND POST-PARTUM OF PRE-ECLAMPTIC WOMEN." Asian Journal of Pharmaceutical and Clinical Research 10, no. 1 (2016): 317. http://dx.doi.org/10.22159/ajpcr.2017.v10i1.15358.

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ABSTRACTObjective: The objectives of the present study were to evaluate the activity of phospholipase A2, plasma elastase enzymes and to assess relation withan inflammatory marker high sensitive C-reactive protein (hs-CRP) in nonpregnant before and after delivery of normotensive pregnant and preeclampticwomen.Methods: The study population consists of three groups: Nonpregnant (Group 1, n=57), normotensive pregnant (Group 2, n=57), and pre-eclampticwomen (Group 3, n=57). Groups 2 and 3 were followed after delivery within 48 hrs. Phospholipase A, plasma elastase, and hs-CRP levels weredetermined

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Uysal, Pelin, Sinem Durmus, Volkan Sozer, et al. "YKL-40, Soluble IL-2 Receptor, Angiotensin Converting Enzyme and C-Reactive Protein: Comparison of Markers of Sarcoidosis Activity." Biomolecules 8, no. 3 (2018): 84. http://dx.doi.org/10.3390/biom8030084.

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The aims of this study were to describe the clinical, radiological and immunological features of a population of sarcoidosis patients and to analyse chitinase-3-like protein 1 (YKL-40), soluble interleukin-2 receptor (sIL-2R), neopterin concentrations and adenosine deaminase (ADA) activity in serum of these patients in order to understand their potential as disease markers. Fifty-nine patients affected by chronic sarcoidosis, in active (20 patients) and inactive (39 patients) phase according to the clinical, radiological and laboratory criteria were studied. Serum YKL-40, sIL-2R, high-sensitiv

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Imani, Mohammad Moslem, Masoud Sadeghi, Farid Farokhzadeh, et al. "Evaluation of Blood Levels of C-Reactive Protein Marker in Obstructive Sleep Apnea: A Systematic Review, Meta‐Analysis and Meta-Regression." Life 11, no. 4 (2021): 362. http://dx.doi.org/10.3390/life11040362.

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(1) Introduction: High sensitivity C-reactive protein (hs-CRP) and CRP are inflammatory biomarkers associated with several inflammatory diseases. In both pediatric and adult individuals with Obstructive Sleep Apnea (OSA) higher hs-CRP and CRP were observed, compared to controls. With the present systematic review, meta-analysis and meta-regression we expand upon previous meta-analyses in four ways: (1) We included 109 studies (96 in adults and 13 in children); (2) we reported subgroup and meta-regression analyses in adults with OSA compared to controls on the serum and plasma levels of hs-CRP;

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Nari, Fatima, Bich Na Jang, Gyu Ri Kim, Eun-Cheol Park, and Sung-In Jang. "Synergistic Effects and Sex Differences in Anthropometric Measures of Obesity and Elevated High-Sensitivity C-Reactive Protein Levels." International Journal of Environmental Research and Public Health 17, no. 21 (2020): 8279. http://dx.doi.org/10.3390/ijerph17218279.

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Background: It remains unclear which anthropometric measure best predicts elevated high-sensitivity C-reactive protein (hs-CRP) levels. This study investigated the association and synergistic interaction of two obesity indices with elevated hs-CRP levels in a national sample of Korean adults, stratified by sex. Methods: The present cross-sectional study used data from the 2015–2018 Korea National Health and Nutrition Examination Survey of 18,610 subjects aged ≥20 years after excluding those with missing variables. Multiple logistic regression analyses and chi-squared tests were performed to in

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Morris, Christopher J., Taylor E. Purvis, Joseph Mistretta, Kun Hu, and Frank A. J. L. Scheer. "Circadian Misalignment Increases C-Reactive Protein and Blood Pressure in Chronic Shift Workers." Journal of Biological Rhythms 32, no. 2 (2017): 154–64. http://dx.doi.org/10.1177/0748730417697537.

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Shift work is a risk factor for inflammation, hypertension, and cardiovascular disease. This increased risk cannot be fully explained by classical risk factors. Shift workers’ behavioral and environmental cycles are typically misaligned relative to their endogenous circadian system. However, there is little information on the impact of acute circadian misalignment on cardiovascular disease risk in shift workers, independent of differences in work stress, food quality, and other factors that are likely to differ between night and day shifts. Thus, our objectives were to determine the independen

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Gebhart, Alana, Monica Young, James Villamere, Anderson Shih, and Ninh T. Nguyen. "Changes in High-sensitivity C-reactive Protein Levels after Laparoscopic Gastric Stapling Procedures versus Laparoscopic Gastric Banding." American Surgeon 80, no. 10 (2014): 1044–48. http://dx.doi.org/10.1177/000313481408001029.

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Obesity, hypertension, diabetes, and hyperlipidemia are risk factors for the development of coronary artery disease. High-sensitivity C-reactive protein (hs-CRP) is an inflammatory biomarker that has been shown to be an independent predictor for cardiovascular risk. The aim of the current study was to examine the changes in cardiovascular risk profile in morbidly obese patients who underwent laparoscopic gastric stapling procedures (bypass and sleeve) compared with laparoscopic gastric banding. Levels of hs-CRP were measured preoperatively and at 12 to 24 months post-operatively. Based on hs-C

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Rector, R. S., Bryan K. Smith, Grace Y. Sun, Ying Liu, and Tom R. Thomas. "C-reactive Protein and Secretory Phospholipase A2 are Unaffected by Exercise or Omega-3 Fatty Acid Supplementation." Medicine & Science in Sports & Exercise 36, Supplement (2004): S326. http://dx.doi.org/10.1097/00005768-200405001-01560.

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Rector, R. S., Bryan K. Smith, Grace Y. Sun, Ying Liu, and Tom R. Thomas. "C-reactive Protein and Secretory Phospholipase A2 are Unaffected by Exercise or Omega-3 Fatty Acid Supplementation." Medicine & Science in Sports & Exercise 36, Supplement (2004): S326. http://dx.doi.org/10.1249/00005768-200405001-01560.

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Stupin, Ana, Lidija Rasic, Anita Matic, et al. "Omega-3 polyunsaturated fatty acids-enriched hen eggs consumption enhances microvascular reactivity in young healthy individuals." Applied Physiology, Nutrition, and Metabolism 43, no. 10 (2018): 988–95. http://dx.doi.org/10.1139/apnm-2017-0735.

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The beneficial effect of omega-3 polyunsaturated fatty acids (PUFA) supplementation on the cardiovascular (CV) system is well supported in CV patients; however, the effect of the consumption of omega-3 PUFA-enriched functional food in healthy individuals is still not fully elucidated. This study aimed to determine the effect of the consumption of omega-3 PUFA-enriched hen eggs on the microvascular reactivity (primary outcome), blood pressure (BP), and serum lipid profile in young healthy individuals. The control group (N = 16) ate 3 ordinary hen eggs (277 mg of omega-3 PUFAs/day), and the OMEG

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Shivappa, Nitin, Susan E. Steck, Thomas G. Hurley, et al. "A population-based dietary inflammatory index predicts levels of C-reactive protein in the Seasonal Variation of Blood Cholesterol Study (SEASONS)." Public Health Nutrition 17, no. 8 (2013): 1825–33. http://dx.doi.org/10.1017/s1368980013002565.

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AbstractObjectiveTo perform construct validation of the population-based Dietary Inflammatory Index (DII) using dietary data from two different dietary assessments and serum high-sensitivity C-reactive protein (hs-CRP) as the construct validator.DesignUsing data derived from (i) three 24 h dietary recalls (24HR) at baseline and at the end of each subsequent quarter (i.e. up to fifteen over a year) and (ii) a 7 d dietary recall (7DDR) measured at baseline and then quarterly, regression analyses were conducted to test the effect of the DII score on serum hs-CRP as dichotomous (≤3 mg/l, >3 mg/

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Zhou, Fu-Chun, Joseph W. Y. Lee, Qi-Hang Zhang, et al. "Higher Serum C-Reactive Protein Levels in Catatonic Patients: A Comparison to Non-catatonic Patients and Healthy Controls." Schizophrenia Bulletin 46, no. 5 (2020): 1155–64. http://dx.doi.org/10.1093/schbul/sbaa041.

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Abstract Catatonia is a psychomotor syndrome defined by a constellation of predominantly motor symptoms. The aim of the present study was to determine whether recently admitted psychiatric patients with catatonia exhibited higher serum C-reactive protein (hs-CRP) levels compared to non-catatonic psychiatric patients and healthy controls (HCs). Recently admitted psychiatric patients were screened and evaluated for the catatonia syndrome using the Bush-Francis Catatonia Rating Scale and the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5). The study sample was formed

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Poudel, Samir K., Aryan Parajuli, Lata Gautam, et al. "Association of High Sensitivity C-Reactive Protein with In-Hospital Mortality in Patients with Acute St-Segment Elevation Myocardial Infarction." Nepalese Heart Journal 17, no. 2 (2020): 33–37. http://dx.doi.org/10.3126/njh.v17i2.32676.

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Background and Aims: Among the various biomarkers, high sensitivity C-Reactive Protein (hs-CRP) has been widely studied and is easy to use in the prognostication of patients with acute ST elevation myocardial infarction (STEMI). This study aimed to associate serum level of hs-CRP with in-hospital mortality in patients presented with acute STEMI. Methods: This was a hospital-based prospective observational study conducted in Shahid Gangalal National Heart Centre among patients presented to the emergency department with chest pain of less than 24 hours duration, who were diagnosed subseque

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Hsu, Heng-Jung, Chiung-Hui Yen, Kuang-Hung Hsu, et al. "Chronic Kidney Disease Stage Is a Modulator on the Association between High-Sensitivity C-Reactive Protein and Coronary Vasospastic Angina." Scientific World Journal 2014 (2014): 1–9. http://dx.doi.org/10.1155/2014/852507.

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The prevalence of coronary vasospasm and also the factors associated with coronary vasospasm in CKD is still unclear. In this cross-sectional study of 859 consecutive CKD patients with angina pectoris received coronary catheterization, we evaluated the factors associated with coronary vasospasm. Patients with vasospasm were older and had higher peripheral blood white cell counts, higher peripheral blood monocyte cell counts, higher haemoglobin levels, higher hs-CRP levels, and lower levels of serum creatinine than patients without vasospasm. The results of multivariate logistic regression anal

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FURMAN, K., A. DI CASTELNUOVO, F. ZITO, G. DE GAETANO, and L. IACOVIELLO. "Genetic variation in alcohol dehydrogenase 3 and the decrease of hs-C-reactive protein levels by moderate alcohol consumption." Journal of Thrombosis and Haemostasis 3, no. 4 (2005): 801–2. http://dx.doi.org/10.1111/j.1538-7836.2005.01257.x.

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Rahbar, A. R., I. Nabipour ., and Z. Amiri . "Effects of Omega-3 Fatty Acids on Serum Lipids and High Sensitivity C Reactive Protein in Cigarette Smokers." Journal of Biological Sciences 7, no. 8 (2007): 1368–74. http://dx.doi.org/10.3923/jbs.2007.1368.1374.

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Sakatani, M., K. Yamanaka, and M. Takahashi. "218 GENE AND PROTEIN EXPRESSION OF ANTIOXIDANT ENZYMES IN BOVINE EMBRYOS EXPOSED TO HEAT SHOCK." Reproduction, Fertility and Development 21, no. 1 (2009): 207. http://dx.doi.org/10.1071/rdv21n1ab218.

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In a previous study, we reported that 8-cell-stage embryos exposed to a temperature of 41°C for 6 h had significantly increased embryonic mortality and intracellular reactive oxygen species (ROS). There have been some reports that ROS regulates the expression of genes encoding antioxidant enzymes in culture cells. In this study, we investigated the gene and protein expression of antioxidant enzymes in bovine 8-cell-stage embryos exposed to heat shock. In vitro-produced bovine embryos were used for the experiment. Embryos were cultured with CR1aa + 5% FCS at 38.5°C in 5% CO2 and 5% O2. On Day 2

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Roman, Yuani M., Adrian V. Hernandez, and C. Michael White. "The Role of Suppressing Inflammation in the Treatment of Atherosclerotic Cardiovascular Disease." Annals of Pharmacotherapy 54, no. 10 (2020): 1021–29. http://dx.doi.org/10.1177/1060028020922994.

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Objective: To review the 3 anti-inflammatory drugs, canakinumab, colchicine, and methotrexate, that have been investigated in major clinical trials for treating patients with atherosclerotic cardiovascular disease (ASCVD). Data Sources: An Ovid MEDLINE literature search (1946 to February 2, 2020) was performed using search strategy [( C-reactive protein OR ASCVD OR cardiac disease OR cardiovascular disease) AND (canakinumab OR methotrexate OR Colchicine)]. Additional references were identified from the citations. Study Selection and Data Extraction: English-language studies assessing the impac

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Pluta, Agnieszka, Paweł Stróżecki, Jacek Kęsy, et al. "Beneficial Effects of 6-Month Supplementation with Omega-3 Acids on Selected Inflammatory Markers in Patients with Chronic Kidney Disease Stages 1–3." BioMed Research International 2017 (2017): 1–7. http://dx.doi.org/10.1155/2017/1680985.

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Introduction. Chronic kidney disease (CKD) is accompanied by inflammation. The aim of this study was to evaluate the effect of 6-month supplementation with omega-3 acids on selected markers of inflammation in patients with CKD stages 1–3. Methods. Six-month supplementation with omega-3 acids (2 g/day) was administered to 87 CKD patients and to 27 healthy individuals. At baseline and after follow-up, blood was taken for C-reactive protein (CRP) and monocyte chemotactic protein-1 (MCP-1) concentration and white blood cell (WBC) count. Serum concentration of omega-3 acids—eicosapentaenoic acid (E

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Pocovi-Gerardino, Gabriela, Maria Correa-Rodríguez, José-Luis Callejas Rubio, et al. "The Relationships of High-Sensitivity C-Reactive Protein and Homocysteine Levels With Disease Activity, Damage Accrual, and Cardiovascular Risk in Systemic Lupus Erythematosus." Biological Research For Nursing 22, no. 2 (2019): 169–77. http://dx.doi.org/10.1177/1099800419889192.

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Chronic inflammation coupled with cardiovascular disease (CVD) risk factors influences the progression of atherosclerosis in systemic lupus erythematosus (SLE). High-sensitivity C-reactive protein (hs-CRP) and homocysteine (Hcy) are associated with the risk of CVD in the general population, but their associations with CV risk and disease activity in SLE are unclear. In this cross-sectional study ( N = 139 SLE patients, mean age = 45.27 ± 13.18 years), we investigated associations between hs-CRP and Hcy levels and disease activity, damage accrual, and CVD risk in SLE. Disease activity and damag

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Kim, Hack-Lyoung, Woo-Hyun Lim, Jae-Bin Seo, Sang-Hyun Kim, Joo-Hee Zo, and Myung-A. Kim. "Improved Prognostic Value in Predicting Long-Term Cardiovascular Events by a Combination of High-Sensitivity C-Reactive Protein and Brachial–Ankle Pulse Wave Velocity." Journal of Clinical Medicine 10, no. 15 (2021): 3291. http://dx.doi.org/10.3390/jcm10153291.

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Background: Both C-reactive protein (CRP) and arterial stiffness are associated with the development of cardiovascular disease (CVD). This study was performed to investigate whether a combination of these two measurements could improve cardiovascular risk stratification. Methods: A total of 6572 consecutive subjects (mean age, 60.8 ± 11.8 years; female, 44.2%) who underwent both high-sensitivity CRP (hs-CRP) and brachial–ankle pulse wave velocity (baPWV) measurement within 1 week were retrospectively analyzed. Major adverse cardiovascular events (MACE), including cardiovascular death, acute my

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