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Journal articles on the topic 'Omeprazole'

Author: Grafiati

Published: 4 June 2021

Last updated: 25 July 2025

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1

Sosnowska, Katarzyna, and Katarzyna Winnicka. "Omeprazole – a new raw material for drug compounding." Farmacja Polska 79, no. 7 (2023): 413–20. http://dx.doi.org/10.32383/farmpol/174998.

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Jednymi z częściej wykonywanych w recepturze leków są preparaty zawierające w swoim składzie omeprazol. Brak substancji pro receptura wymuszał korzystanie z leku gotowego w postaci peletek. Wprowadzenie na rynek farmaceutyczny omeprazolu jako surowca farmaceutycznego ułatwia wykonywanie leków z omeprazolem, należy jednak pamiętać o możliwości rozkładu substancji w środowisku kwasowym. Celem pracy była ocena trwałości recepturowych zawiesin z omeprazolem w postaci proszku (surowca do receptury), zawierających w swoim składzie glicerol, syrop prosty lub glukozę. Jako substancję zapewniającą odpo

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2

Sartika, Eria, Eko Suhartono, and Agung Biworo. "PENGARUH LANSOPRAZOL DAN OMEPRAZOL TERHADAP AKTIVITAS ENZIM KATALASE HEPAR TIKUS." Berkala Kedokteran 12, no. 2 (2016): 255. http://dx.doi.org/10.20527/jbk.v12i2.1875.

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Abstract: Lansoprazole and omeprazole is a Proton Pump Inhibitor class of drugs that are often used for the treatment of peptic ulcers. Lansoprazole and omeprazole have an influence on the various target organs exposed. Mechanism of lansoprazole and omeprazole in influencing the activity of the enzyme catalase is competing with absolute catalase enzyme substrate (H2O2) in the binding of the enzyme active site. This study aims to determine the effect of lansoprazole and omeprazole against liver catalase enzyme activity. This study was a laboratory experimental study conducted in three groups, n

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3

Fienda, Adrully El, and Ainun Wulandari. "Analisis Efektivitas Biaya Penggunaan Omeprazol dan Pantoprazol dalam Terapi Peptic Ulcer pada Pasien Lansia Rawat Inap di Rumah Sakit Umum Adhyaksa." Jurnal Farmasi Higea 14, no. 2 (2022): 169. http://dx.doi.org/10.52689/higea.v14i2.475.

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PPI (proton pump inhibitors) adalah salah satu obat yang umum diresepkan pada gangguan lambung. Penelitian ini bertujuan untuk mengetahui nilai efektivitas biaya pada penggunaan Omeprazol dan Pantoprazol pada pasien rawat inap di RSU Adhyaksa. Penelitian ini menggunakan metode deskriptif kuantitatif dengan pengambilan data secara retrospektif dengan membandingkan Direct Medical Cost (biaya medik langsung). Subjek dari penelitian ini adalah semua pasien rawat inap di RSU Adhyaksa yang mendapatkan terapi Omeprazol dan Pantoprazol dengan usia >50 tahun dalam periode Januari 2020 – Mei 2022. Ha

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4

Hutahaean, Amsaline, Gayatri Citraningtyas, and Defny S. Wewengkang. "ANALISIS EFEKTIVITAS BIAYA PADA PASIEN GASTRITIS RAWAT INAP DI RUMAH SAKIT BHAYANGKARA MANADO." PHARMACON 8, no. 4 (2019): 767. http://dx.doi.org/10.35799/pha.8.2019.29351.

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ABSTRACTGastritis is an inflammatory process in the gastric mucosa and submucosa or health problems caused by irritation and infection factors. Treatment therapy used in gastritis is the proton pump inhibitor (PPI), H2 receptor antagonists, and antacids. Giving treatment therapy used by patients has an impact on the amount of medical expenses. The purpose of this study was to determine a more cost effective therapy between the use of omeprazole and lansoprazole in hospitalized gastrtitis patients at Bhayangkara Hospital, Manado. The method used in this study is Cost Effectiveness Analysis with

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5

Nasrullah, Mohammed Z., Khalid Eljaaly, Thikryat Neamatallah, et al. "Omeprazole Prevents Colistin-Induced Nephrotoxicity in Rats: Emphasis on Oxidative Stress, Inflammation, Apoptosis and Colistin Accumulation in Kidneys." Pharmaceuticals 15, no. 7 (2022): 782. http://dx.doi.org/10.3390/ph15070782.

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The clinical value of colistin, a polymyxin antibiotic, is limited by its nephrotoxicity. Omeprazole is a commonly prescribed proton pump inhibitor. The current study aimed to evaluate the effects of the concomitant administration of omeprazole on colistin-induced nephrotoxicity in rats. Omeprazole significantly ameliorated colistin nephrotoxicity as evidenced by prevention in the rise in the serum level of creatinine, urea and cystactin C as well as urinary N-acetylglucosamine activity. This was confirmed by histological studies that indicated a decreased incidence of interstitial nephritis,

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6

Karan, Agale*1 Neha Said2 Vishal Madankar3. "Formulation and Evaluation of Omeprazole Floating Tablet for The Treatment of Peptic Ulcer." International Journal of Scientific Research and Technology 2, no. 6 (2025): 33–40. https://doi.org/10.5281/zenodo.15568974.

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Peptic ulcers, Zollinger-Ellison syndrome, and acid-related gastrointestinal illnesses including Gastroesophageal Reflux Disease (GERD) can all be effectively treated with omeprazole, a popular proton pump inhibitor (PPI). Omeprazole's traditional formulation, however, has drawbacks including low bioavailability and quick stomach emptying, which lowers its therapeutic effectiveness. The creation of omeprazole floating tablets has shown promise as a solution to these issues. By providing extended gastric retention and improving drug release at the site of action, these tablets are made to float

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7

Javed, Mamoona, Muhammad Hayder Ali, Muhammad Saad Tanveer, and Muhammad Hassan Tanveer. "Omeprazole vs Lansoprazole in the Management of Gastroesophageal Reflux Disease: A Systematic Literature Review." Journal of Medical Research and Innovation 4, no. 2 (2020): e000204. http://dx.doi.org/10.32892/jmri.204.

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Objective: To evaluate the effectiveness and safety of omeprazole compared to lansoprazole in Gastroesophageal reflux disease patients (GERD). Methods: A systematic search of MEDLINE, EMBASE (inception to December 2019) and CENTRAL (January 2011 to December 2019) was conducted to identify the relevant articles. A detailed inclusion-exclusion criterion was developed and implemented to screen the abstracts. Full texts of the selected abstracts were then assessed to establish their inclusion or exclusion in our review. Cochrane risk of bias criterion was used to assess the methodological qu

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8

&NA;. "Omeprazole see Furosemide/omeprazole." Reactions Weekly &NA;, no. 354 (1991): 11. http://dx.doi.org/10.2165/00128415-199103540-00049.

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9

Rouaz-El-Hajoui, Khadija, Encarnación García-Montoya, Marc Suñé-Pou, Josep María Suñé-Negre, and Pilar Pérez-Lozano. "Application of Galenic Strategies for Developing Gastro-Resistant Omeprazole Formulation for Pediatrics." Children 11, no. 8 (2024): 945. http://dx.doi.org/10.3390/children11080945.

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Objectives: This study addresses a critical need in pediatric pharmacotherapy by focusing on the development of an enteric formulation of omeprazole for pediatric use. Omeprazole, a widely used proton pump inhibitor, is essential for treating various gastrointestinal disorders in children. The main objective is to design a compounding formula that can be prepared in hospital pharmacy services without the need for industrial equipment, which is often unavailable in these settings. Methods: The research applied different galenic strategies to overcome the challenges of omeprazole’s instability i

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10

Soliman, Amira, Leyanis Rodriguez-Vera, Ana Alarcia-Lacalle, et al. "Leveraging Omeprazole PBPK/PD Modeling to Inform Drug–Drug Interactions and Specific Recommendations for Pediatric Labeling." Pharmaceutics 17, no. 3 (2025): 373. https://doi.org/10.3390/pharmaceutics17030373.

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Background/Objectives: Omeprazole is widely used for managing gastrointestinal disorders like GERD, ulcers, and H. pylori infections. However, its use in pediatrics presents challenges due to drug interactions (DDIs), metabolic variability, and safety concerns. Omeprazole’s pharmacokinetics (PK), primarily influenced by CYP2C19 metabolism, is affected by ontogenetic changes in enzyme expression, complicating dosing in children. Methods: This study aimed to develop and validate a physiologically based pharmacokinetic (PBPK) model for omeprazole and its metabolites to predict age-related variati

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11

Skvortsova, T. A., G. Yu Knorring, and E. N. Kareva. "Use of Omeprazole in Paediatric Patients in Russia." Doctor.Ru 20, no. 10 (2021): 39–43. http://dx.doi.org/10.31550/1727-2378-2021-20-10-39-43.

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Objective of the Review: To analyse clinical and pharmacological characteristics and normative documents in the use of modern proton pump inhibitors (PPI) in paediatric patients in the Russian Federation. Key Points. PPIs remain a widely used and efficient therapy of acid-related disorders in children; however, prescription should be based not only on clinical characteristics of a patient, but also on normative documents, e.g., instructions for the use of PPIs in paediatric population for certain indications approved by the Ministry of Health of Russia, since healthcare providers are responsib

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12

Kulcsár, Margaréta, Michaela Karamanová, František Novotný, Zuzana Vilhanová, Martina Pettenello, and Csilla Tóthová. "Phytotherapy compared to omeprazol therapy in equine gastric ulcers." Acta Veterinaria Brno 91, no. 4 (2022): 309–15. http://dx.doi.org/10.2754/avb202291040309.

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The aim of this study was to offer an alternative therapy for gastric ulcers in horses as the interest in natural products is growing not only among practicioners but also horse owners. We compared the treatment of equine gastric squamous mucosa ulcers by omeprazol and by nutraceutical herbal mixture PREVUL (Dzsar Ltd., FitoCavallo, Hungary). A total of 36 horses, 18 geldings, 15 non-pregnant mares and 3 stallions were diagnosed with Equine Squamous Gastric Disease (ESGD) by gastroscopy. Horses were randomly divided into three groups. The first group was treated with 4 mg/kg omeprazole paste (

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13

&NA;. "Omeprazole." Reactions Weekly &NA;, no. 1382 (2011): 28. http://dx.doi.org/10.2165/00128415-201113820-00100.

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&NA;. "Omeprazole." Reactions Weekly &NA;, no. 1386 (2012): 29–30. http://dx.doi.org/10.2165/00128415-201213860-00102.

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&NA;. "Omeprazole." Reactions Weekly &NA;, no. 1390 (2012): 28. http://dx.doi.org/10.2165/00128415-201213900-00108.

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&NA;. "Omeprazole." Reactions Weekly &NA;, no. 1391 (2012): 32. http://dx.doi.org/10.2165/00128415-201213910-00116.

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17

&NA;. "Omeprazole." Reactions Weekly &NA;, no. 703 (1998): 10. http://dx.doi.org/10.2165/00128415-199807030-00035.

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&NA;. "Omeprazole." Reactions Weekly &NA;, no. 713 (1998): 9. http://dx.doi.org/10.2165/00128415-199807130-00025.

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&NA;. "Omeprazole." Reactions Weekly &NA;, no. 716 (1998): 12. http://dx.doi.org/10.2165/00128415-199807160-00041.

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20

&NA;. "Omeprazole." Reactions Weekly &NA;, no. 716 (1998): 13. http://dx.doi.org/10.2165/00128415-199807160-00046.

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21

&NA;. "Omeprazole." Reactions Weekly &NA;, no. 723 (1998): 10. http://dx.doi.org/10.2165/00128415-199807230-00032.

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22

&NA;. "Omeprazole." Reactions Weekly &NA;, no. 743 (1999): 10–11. http://dx.doi.org/10.2165/00128415-199907430-00030.

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23

&NA;. "Omeprazole." Reactions Weekly &NA;, no. 743 (1999): 11. http://dx.doi.org/10.2165/00128415-199907430-00033.

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24

&NA;. "Omeprazole." Reactions Weekly &NA;, no. 746 (1999): 9. http://dx.doi.org/10.2165/00128415-199907460-00028.

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&NA;. "Omeprazole." Reactions Weekly &NA;, no. 751 (1999): 10. http://dx.doi.org/10.2165/00128415-199907510-00034.

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&NA;. "Omeprazole." Reactions Weekly &NA;, no. 758 (1999): 10. http://dx.doi.org/10.2165/00128415-199907580-00032.

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&NA;. "Omeprazole." Reactions Weekly &NA;, no. 1194-1195 (2008): 28. http://dx.doi.org/10.2165/00128415-200811940-00103.

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&NA;. "Omeprazole." Reactions Weekly &NA;, no. 1135 (2007): 24. http://dx.doi.org/10.2165/00128415-200711350-00095.

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&NA;. "Omeprazole." Reactions Weekly &NA;, no. 1136 (2007): 21. http://dx.doi.org/10.2165/00128415-200711360-00064.

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&NA;. "Omeprazole." Reactions Weekly &NA;, no. 1138 (2007): 21. http://dx.doi.org/10.2165/00128415-200711380-00061.

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&NA;. "Omeprazole." Reactions Weekly &NA;, no. 1143 (2007): 20. http://dx.doi.org/10.2165/00128415-200711430-00066.

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&NA;. "Omeprazole." Reactions Weekly &NA;, no. 1149 (2007): 19. http://dx.doi.org/10.2165/00128415-200711490-00060.

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&NA;. "Omeprazole." Reactions Weekly &NA;, no. 1153 (2007): 21. http://dx.doi.org/10.2165/00128415-200711530-00070.

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&NA;. "Omeprazole." Reactions Weekly &NA;, no. 1158 (2007): 22. http://dx.doi.org/10.2165/00128415-200711580-00061.

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35

&NA;. "Omeprazole." Inpharma Weekly &NA;, no. 1203 (1999): 16. http://dx.doi.org/10.2165/00128413-199912030-00026.

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&NA;. "Omeprazole." Reactions Weekly &NA;, no. 1359 (2011): 29. http://dx.doi.org/10.2165/00128415-201113590-00112.

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&NA;. "Omeprazole." Reactions Weekly &NA;, no. 1361 (2011): 31. http://dx.doi.org/10.2165/00128415-201113610-00112.

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&NA;. "Omeprazole." Reactions Weekly &NA;, no. 1361 (2011): 31. http://dx.doi.org/10.2165/00128415-201113610-00114.

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&NA;. "Omeprazole." Reactions Weekly &NA;, no. 1366 (2011): 23–24. http://dx.doi.org/10.2165/00128415-201113660-00089.

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&NA;. "Omeprazole." Reactions Weekly &NA;, no. 532 (1994): 13. http://dx.doi.org/10.2165/00128415-199405320-00047.

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&NA;. "Omeprazole." Reactions Weekly &NA;, no. 533 (1995): 9. http://dx.doi.org/10.2165/00128415-199505330-00033.

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&NA;. "Omeprazole." Reactions Weekly &NA;, no. 538 (1995): 12. http://dx.doi.org/10.2165/00128415-199505380-00049.

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&NA;. "Omeprazole." Reactions Weekly &NA;, no. 540 (1995): 10. http://dx.doi.org/10.2165/00128415-199505400-00033.

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44

&NA;. "Omeprazole." Reactions Weekly &NA;, no. 547 (1995): 10. http://dx.doi.org/10.2165/00128415-199505470-00027.

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&NA;. "Omeprazole." Reactions Weekly &NA;, no. 551 (1995): 9. http://dx.doi.org/10.2165/00128415-199505510-00035.

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&NA;. "Omeprazole." Reactions Weekly &NA;, no. 558 (1995): 10. http://dx.doi.org/10.2165/00128415-199505580-00029.

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&NA;. "Omeprazole." Reactions Weekly &NA;, no. 560 (1995): 9. http://dx.doi.org/10.2165/00128415-199505600-00027.

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48

&NA;. "Omeprazole." Reactions Weekly &NA;, no. 564 (1995): 10. http://dx.doi.org/10.2165/00128415-199505640-00027.

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&NA;. "Omeprazole." Reactions Weekly &NA;, no. 566 (1995): 10. http://dx.doi.org/10.2165/00128415-199505660-00038.

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&NA;. "Omeprazole." Reactions Weekly &NA;, no. 567 (1995): 9. http://dx.doi.org/10.2165/00128415-199505670-00031.

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