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Dissertations / Theses on the topic 'Onchocerca'

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Published: 4 June 2021
Last updated: 17 February 2022

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1

Silva, Verônica Marchon da. "Estudo epidemiológico para a avaliação da eliminação da Oncocercose em áreas sentinelas da Região Amazônica, Brasil." reponame:Repositório Institucional da FIOCRUZ, 2015. http://www.arca.fiocruz.br/handle/icict/15057.

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Submitted by Angelo Silva (asilva@icict.fiocruz.br) on 2016-07-13T18:31:00Z No. of bitstreams: 2 license.txt: 1748 bytes, checksum: 8a4605be74aa9ea9d79846c1fba20a33 (MD5) 71824.pdf: 2172041 bytes, checksum: 706d176d456c37e0c405bbdd3df5101a (MD5)<br>Approved for entry into archive by Anderson Silva (avargas@icict.fiocruz.br) on 2016-07-21T19:07:35Z (GMT) No. of bitstreams: 2 71824.pdf: 2172041 bytes, checksum: 706d176d456c37e0c405bbdd3df5101a (MD5) license.txt: 1748 bytes, checksum: 8a4605be74aa9ea9d79846c1fba20a33 (MD5)<br>Made available in DSpace on 2016-07-21T19:07:35Z (GMT). No. of bi
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2

Tree, Timothy Ian Martin. "Molecular characterisation of Onchocerca volvulus antigens." Thesis, Imperial College London, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.321651.

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3

Krause, Stephanie. "Untersuchungen zur Genstruktur und Genexpression an Glutathion-S-Transferasen der Nematoden Onchocerca volvulus (Leukart 1893) und Caenorhabditis elegans (Maupas 1900)." [S.l. : s.n.], 2002. http://deposit.ddb.de/cgi-bin/dokserv?idn=965211924.

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4

Eng, Jeffrey K. L. "Genetic selection by ivermectin on Onchocerca volvulus." Thesis, McGill University, 2006. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=111844.

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Onchocerca volvulus is a parasitic filarial nematode responsible for human onchocerciasis, a disease commonly known as "River Blindness". Although there are no well documented cases of ivermectin resistance in O. volvulus, reports of suboptimal responses to ivermectin have appeared. The purpose of this thesis was to examine genetic polymorphisms in O. volvulus and to determine whether there was genetic evidence of ivermectin selection on O. volvulus genes. Analysis of 17 genes from O. volvulus was undertaken in two populations of worms, either from ivermectin-naive patients or from patients wh
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5

Jenkins, Rosalind Elspeth. "Characterization od recombinant antigens of Onchocerca volvulus." Thesis, University of Liverpool, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.240476.

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6

Bourguinat, Catherine. "Effects of ivermectin on Onchocerca volvulus adult worms." Thesis, McGill University, 2007. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=111889.

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Ivermectin (IVM) is the only safe drug for mass-treatment of onchocerciasis. IVM-resistance has been reported in gastrointestinal nematode parasites of animals. A reduction in response to IVM in Onchocerca volvulus could have significant consequences for the onchocerciasis control programs. Over the last few years, studies have reported genetic selection or reduced responses to IVM in some O. volvulus populations. The risk of a recrudescence of the disease was recently reported with the emergence of resistant adult parasite population in Ghana. It is important to understand the effects of IVM
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7

Halstead, Meredith. "Putative glutamate-gated chloride channels from Onchocerca volvulus." Thesis, McGill University, 2002. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=29439.

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Onchocerca volvulus, a filarial nematode, is the causative agent of onchocerciasis.<br>O. volvulus is a human parasite with no animal model host and is endemic in the tropics. O. volvulus material is scarce and must be conserved as part of the Onchocerciasis Control Program. A genomic library was constructed to provide a substantial source of renewable genetic material, in place of original parasite DNA.<br>Currently there is only one glutamate-gated chloride channel that has been sequenced from O. volvulus, but this has not yet been characterized. This GluClx partial cDNA sequence isolated by
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8

Murray, Katherine Alice. "Characterisation of repetitive DNA sequences of Onchocerca species." Thesis, University of Liverpool, 1989. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.280851.

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9

Van, Eldik Annamaria Johanna. "Synthesis of glutathione conjugates as selective inhibitors for parasitic glutathione S transferases." Thesis, De Montfort University, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.246521.

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10

Cabrera, Z. Y. "Characterisation of Onchocerca antigens and their application to diagnosis." Thesis, Brunel University, 1988. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.233303.

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11

McCall, Philip John. "Studies on the transmission of bovine onchocerciasis in North Wales." Thesis, University of Liverpool, 1986. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.328187.

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12

Zimmerman, Peter Allen. "The evolution of a repeated DNA sequence can be used to classify Onchocerca." Case Western Reserve University School of Graduate Studies / OhioLINK, 1992. http://rave.ohiolink.edu/etdc/view?acc_num=case1056550224.

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13

Martins, Marina Isabel Marques. "Estudo epidemiológico sobre a prevalência de filárias cutâneas em cães e gatos nas regiões de Elvas e centro de Lisboa." Master's thesis, Universidade de Évora, 2021. http://hdl.handle.net/10174/29734.

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O número de casos de filariose em animais e humanos tem vindo a aumentar por todo o mundo. Estes parasitas possuem um ciclo de vida indireto tendo um artrópode hematófago como hospedeiro intermediário. O parasita Onchocerca lupi pode afetar cães, gatos e humanos, provocando sintomas oculares. A espécie Cercopithifilaria spp. é outra filária que afeta cães onde a patogenicidade ainda está por esclarecer. A região do mediterrâneo proporciona as condições para a transmissão e desenvolvimento dos parasitas no hospedeiro definitivo, tendo sido reportados casos em Portugal. O presente trabalho anali
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14

Adjami, Ako Aimé Gilles. "Contribution à la surveillance entomologique et épidémiologique de l'onchocercose en Afrique de l’Ouest." Montpellier 2, 2006. http://www.theses.fr/2006MON20137.

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En Afrique de l'Ouest, cette endémie parasitaire n'est plus un problème de santé publique, ni un obstacle au développement socio-économique. Cependant, l’OCP n’ayant visé l’éradication ni du vecteur (Simulium damnosum s. L. ), ni du parasite (Onchocerca volvulus), ces composantes du système pathogène persistent. Contrairement aux foyers onchocerquiens d’Amérique Centrale et du Sud, l’éradication de l’onchocercose en Afrique n’est pas envisageable dans la plupart des foyers, avec les outils actuels de lutte que sont l’ivermectine et la lutte anti-vectorielle. L’un des obstacles à l’éradication
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15

Salinas, M. S. "Characterisation and molecular cloning of glutathione S-transferases from Onchocerca volvulus." Thesis, University of Cambridge, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.361766.

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16

Osei-Atweneboana, Mike Yaw 1966. "Molecular epidemiology of emerging ivermectin resistance in onchocerciasis." Thesis, McGill University, 2008. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=111910.

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Onchocerciasis, commonly known as "River blindness" is a disease affecting over 37 million people, worldwide. It is caused by the parasitic nematode Onchocerca volvulus and transmitted by the blackfly vector of the genus Simulium. The drug ivermectin (IVM) is the principal means of controlling the disease. As a result of recent reports on sub-optimal response to ivermectin and genetic selection in O. volvulus, we carried out a 21 month epidemiological study to investigate the response of O. volvulus to repeated rounds of IVM treatments in 2501 subjects from 19 Ghanaian communities that have re
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17

Drabner, Birgit. "Charakterisierung und Identifizierung von immundominanten Bereichen der L3-Chitinase von Onchocerca volvulus." Doctoral thesis, [S.l.] : [s.n.], 2000. http://deposit.ddb.de/cgi-bin/dokserv?idn=959660488.

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18

Schönemeyer, Annett. "Charakterisierung der immunmodulierenden Wirkung eines Cysteinproteasen-Inhibitors der humanpathogenen Filarie Onchocerca volvulus." [S.l.] : [s.n.], 2000. http://deposit.ddb.de/cgi-bin/dokserv?idn=961845554.

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19

Tchakoute, Virginia Louise. "Onchocerca ochengi : susceptibility and resistance to natural infection in West African cattle." Thesis, University of Liverpool, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.366271.

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20

Njongmeta, Leo Moh. "Immunity in onchocerciasis after ivermectin prophylaxis : studies with Onchocerca ochengi in cattle." Thesis, University of Liverpool, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.250397.

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21

Schönemeyer, Annett. "Charakterisierung der immunmodulierenden Wirkung eines Cysteinproteasen-Inhibitors der humanpathogenen Filarie Onchocerca volvulus." Doctoral thesis, Humboldt-Universität zu Berlin, Mathematisch-Naturwissenschaftliche Fakultät I, 2000. http://dx.doi.org/10.18452/14594.

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Filarien persistieren bis zu 15 Jahren in ihren Wirten. Als eine Ursache dieser Persistenz diskutiert man die Fähigkeit der Filarien, die Immunantwort des Wirtes gezielt zu modulieren und eine zelluläre Hyporeaktivität zu induzieren. In der vorliegenden Arbeit wurde untersucht, ob ein sezernierter Cysteinproteasen-Inhibitor (Onchocystatin) der humanpathogenen Filarie Onchocerca volvulus immunmodulierende Eigenschaften besitzt und an der Herausbildung eines hyporeaktiven Immunstatus des Wirtes beteiligt ist. Für die Untersuchungen wurde Onchocystatin als full length Molekül (rOv17) und als verk
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22

Tamarozzi, Francesca. "Wolbachia endosymbiont of Onchocerca volvulus : driver of immunopathology and target for therapy." Thesis, University of Liverpool, 2012. http://livrepository.liverpool.ac.uk/7855/.

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Onchocerciasis affects an estimated 37 million people in Sub-Saharan Africa and Latin America, causing debilitating skin and eye disease and accounting for a global loss of 1 million Disability-Adjusted Life-Years. The discovery of Wolbachia bacterial endosymbionts in filarial nematodes, including Onchocerca volvulus, has revolutionised the understanding of the parasite’s biology and immunopathogenic mechanisms of disease, and has offered a novel approach to its treatment and control with anti-Wolbachia antibiotics. Treatment with doxycycline is effective at sterilising and killing adult O. vo
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23

Marreiros, Ruben Miguel da Palma. "Oncocercose ocular canina." Master's thesis, Universidade de Évora, 2013. http://hdl.handle.net/10174/10720.

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O estágio curricular em clínica de animais de companhia que originou este relatório teve lugar no INEMVET HV num período de 5 meses. A primeira parte deste relatório corresponde à casuística resultante das atividades desenvolvidas neste período, sendo que a segunda parte corresponde à revisão bibliográfica subordinada ao tema – oncocercose ocular canina (OOC). Desde 1991 têm sido reportados cada vez mais casos de OOC na literatura mundial. No presente relatório procurarei descrever a morfologia, características moleculares, ciclo biológico, características dos vetores, distribuição geográfica
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24

Höckh, Florestan Gerald. "Untersuchungen zur biologischen Wirkung von Onchocerca-volvulus-Proteinen auf Monozyten, Makrophagen in vitro." [S.l.] : [s.n.], 2005. http://deposit.ddb.de/cgi-bin/dokserv?idn=976135477.

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25

Lehmann, Tovi. "Onchocerca lienalis in Simulium vittatum: Navigation of microfilariae and the fly defense response." Diss., The University of Arizona, 1994. http://hdl.handle.net/10150/186626.

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A rapid clearance of a third of the number of Onchocerca lienalis microfilariae injected into Simulium vittatum, a laboratory host, occurred within 2 hr post inoculation (pi) regardless of dose. A second injection, 2.5 hr after the first, resulted in a lower proportion of microfilariae eliminated, suggesting that availability of active factors were reduced after the first inoculation. Microfilariae did not differ in their susceptibility to clearance as microfilariae that were recovered 2 hr pi and reinoculated into other flies were eliminated faster than unexposed controls. In S. jenningsi, a
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26

Macfarlane, C. L. "Circulating biomarkers of Onchocerca volvulus for diagnosis of infection and antifilarial treatment efficacy." Thesis, University of Liverpool, 2018. http://livrepository.liverpool.ac.uk/3021511/.

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27

Bolcen, Shanna June. "Molecular Evidence for Vector Implication of Onchocerca lupi in Los Angeles County, CA." Scholar Commons, 2014. https://scholarcommons.usf.edu/etd/4988.

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Onchocerca is a genus of roundworm most commonly associated with the human infection onchocerciasis, or river blindness. While typically a zoonotic infection of ungulate populations, canine cases (Onchocerca lupi) have been identified in the United States and Greece. In 2012, Los Angeles County, Veterinary Public Health Program identified 3 cases of Onchocerca spp. infections in domestic canines. Samples from the ensuing blackfly collections were sent to the Global Health Infectious Disease Research Unnasch Laboratory for parasite isolation and vector species identification. Species-specific p
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28

Eisenbarth, Albert [Verfasser], and Alfons [Akademischer Betreuer] Renz. "The biology of Onchocerca ochengi, a filarial nematode from African cattle, and the implications on the epidemiology of the causative agent of river blindness, Onchocerca volvulus / Albert Eisenbarth ; Betreuer: Alfons Renz." Tübingen : Universitätsbibliothek Tübingen, 2016. http://d-nb.info/1163665045/34.

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29

Sommer, Alexandra. "Glutathion-abhängige Entgiftungssysteme der Nematoden Onchocerca volvulus (Leukart, 1893) und Caenorhabditis elegans (Maupas, 1900)." [S.l.] : [s.n.], 2002. http://deposit.ddb.de/cgi-bin/dokserv?idn=966002695.

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30

Hansen, Rowena Dawn Ellen. "The potential role of Walbachia as a defensive mutualist in the Onchocerca ochengi nodule." Thesis, University of Liverpool, 2011. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.569645.

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Onchocerciasis (River Blindness) is a continuing major cause of human blindness, skin disease and socioeconomic impediment in sub-Saharan Africa and Latin America. An estimated 37 million people are infected and a further 89 million are at risk. Human onchocerciasis is caused by the filarial nematode Onchocerca volvulus, and is spread by the blackfly vector Simulium spp, found in riverine areas, encompassing land which is agriculturally valuable. Ivermectin is currently distributed in these areas to control the microfilarial stage of the parasite, but adult worm viability is unaffected. Thus,
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31

Hildebrandt, Julia [Verfasser], and Adrian [Akademischer Betreuer] Streit. "Population genetic studies in the parasitic nematode Onchocerca ochengi / Julia Hildebrandt ; Betreuer: Adrian Streit." Tübingen : Universitätsbibliothek Tübingen, 2014. http://d-nb.info/1196802262/34.

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32

Hogarth, Philip John. "Mechanisms of acquired immunity against the microfilariae of Onchocerca lienalis in a mouse model." Thesis, University of Liverpool, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.263781.

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33

Herder, Stéphane. "Variabilité génétique d'"Onchocerca volvulus" (Leuckart, 1893). Relations avec les faciès épidémiologiques de l'onchocercose." Montpellier 2, 1994. http://www.theses.fr/1994MON20093.

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La variabilite genetique d'onchocerca volvulus a ete etudiee sur plusieurs isolats du cameroun. Cette filaire est la deuxieme cause infectieuse de cecite dans le monde et affecte, selon l'oms, environ 17 millions de personnes en afrique et en amerique latine. La complexite de l'epidemiologie de l'onchocercose apparait liee a l'existence de differentes souches du parasite qui sont a l'origine de taux de cecites tres variables selon les regions etudiees. Plusieurs types de marqueurs ont ete utilises pour etudier differentes populations d'o. Volvulus du cameroun ; les sondes specifiques des souch
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34

Margutti, Pinto Maria Elizabeth Bernades. "Isolation and characterization of a β-tubulin gene from the filarial worm Onchocerca gibsoni". Thesis, University of Edinburgh, 1991. http://hdl.handle.net/1842/19983.

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Onchocerciasis or river blindness is a major cause of infectious blindness in the world. In severely affected areas, half of the adult population may be blinded by the disease. The human parasite, <i>O.volvulus</i>, is very closely related to the cattle parasite <i>Onchocerca gibsoni</i> which provides an abundant source of biological material for analysis. Thus, <i>O.gibsoni</i> offers a model system for biochemical analysis and drug screening. In these organisms, as in other eukaryotes, microtubules are essential, multifunctional, subcellular components. They are involved in chromosome segre
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35

Höppner, Jana. "Molekulare Charakterisierung der Glutathion-S-Transferasen OvGST1, OvGST2 und OvGST3 aus Onchocerca volvulus (Leuckart, 1893)." [S.l.] : [s.n.], 2006. http://deposit.ddb.de/cgi-bin/dokserv?idn=980179696.

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36

Cross, Helen Fiona. "A molecular and pharmacological investigation of the action of ivermectin against Onchocerca ochengi of cattle." Thesis, University of Liverpool, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.266171.

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37

Barrault, Denise Viviane. "The putative role of humoral antibacterial peptides on Onchocerca spp. transmission by simuliids (Diptera: Simuliidae)." Thesis, Keele University, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.311729.

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38

Talsma, Alex Jeanne. "Development of a Confirmatory PCR Assay to Detect Onchocerca volvulus in Pools of Vector Black Flies." Scholar Commons, 2013. http://scholarcommons.usf.edu/etd/4952.

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Onchocerciasis, or river blindness, has historically represented one of the significant neglected tropical diseases on the planet in terms of socio-economic impact. The discovery that ivermectin was a safe and effective treatment for onchocerciasis, together with the decision of the manufacturer to donate the drug for the treatment of this disease became the basis for several large international programs to control and eventually eliminate the infection. These programs have managed to virtually eliminate transmission of the parasite causing Onchocerca volvulus from many foci in Africa and th
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39

Lattemann, Claus [Verfasser]. "Entwicklung von rekombinanten attenuierten Salmonella-Vakzinstämmen zur Immunprophylaxe von Onchocerca-volvulus-Infektionen / vorgelegt von Claus Lattemann." Augsburg, Schöpplerstr. 13 : C. Lattemann, 2000. http://d-nb.info/963189263/34.

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40

Pion, Sébastien Boussinesq Michel. "Contribution à la modélisation des filarioses à "Onchocerca volvulus" et à "Loa loa" en Afrique centrale." Créteil : Université de Paris-Val-de-Marne, 2004. http://doxa.scd.univ-paris12.fr:80/theses/th0214004.pdf.

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Pion, Sébastien. "Contribution à la modélisation des filarioses à "Onchocerca volvulus" et à "Loa loa" en Afrique centrale." Paris 12, 2004. https://athena.u-pec.fr/primo-explore/search?query=any,exact,990002140040204611&vid=upec.

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L'onchocercose, parasitose provoquée par la filaire Onchocerca volvulus, est transmise par des diptères se reproduisant dans les cours d'eau rapides, les simulies. Elle constitue un problème de santé publique majeur en Afrique, où 18 millions de personnes sont infectées. La cécité, principale complication de la maladie, touche environ 300. 000 individus. Depuis les années 1990, la lutte contre l'onchocercose repose sur le traitement de masse annuel des populations par un médicament actif sur les embryons du parasite, l'ivermectine. L'impact des traitements ne peut être évalué que si l'on conna
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Ali, Magdi Mahmoud M. "The immunologic aspects of the pathogenesis of human onchocerciasis /." Stockholm : Dept. of immunology, Wenner-Gren institute, Stockholm university, 2006. http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-793.

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43

Guzmán, Laparra Gabriel Eduardo. "Use of affordable technology for the sensitive and specific diagnosis of onchocerciasis (river blindness) /." Stockholm, 2002. http://diss.kib.ki.se/2002/91-7349-321-x.

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Pantchev, Nikola. "Konservierte Gene für Oberflächenproteine der Mikrofilarienscheide bei den unbescheidete Mikrofilarien freisetzenden Arten Acanthocheilonema viteae und Onchocerca volvulus." Giessen VVB Laufersweiler, 2006. http://geb.uni-giessen.de/geb/volltexte/2006/3499/index.html.

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45

Basanez, Maria Gloria. "Density-dependent processes in the transmission of human onchoceriasis with particular reference to the 'Onchocerca-Simulium' interaction." Thesis, Imperial College London, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.244160.

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Nfon, Charles Kongnyu. "The interaction between chemotherapy and immune responses in natural Onchocerca ochengi infection, the bovine host and the endosybiotic bacteria, Wolbachia." Thesis, University of Liverpool, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.406667.

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47

Adamu, Robert. "Molecular and Functional Characterization of Onchocerca volvulus Gene Products (Ov58GPCR and Ov-DKR-1) in the Control of Human Onchocerciasis." Doctoral thesis, Universite Libre de Bruxelles, 2018. http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/279609.

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Onchocerciasis is a severely debilitating yet neglected tropical disease (NTD) currently affecting approximately 15.5 million people, including 12.2 million people with skin disease and 1.025 million with vision loss. The disease causes social stigma, generates and perpetuates poverty, and leads ultimately to irreversible unilateral or bilateral blindness if untreated. Consequently, onchocerciasis is a major impediment to socioeconomic development in addition to being a major public health concern in some African countries. Many control programs have been launched against the disease with mode
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48

Pantchev, Nikola [Verfasser]. "Konservierte Gene für Oberflächenproteine der Mikrofilarienscheide bei den unbescheidete Mikrofilarien freisetzenden Arten Acanthocheilonema viteae und Onchocerca volvulus / eingereicht von Nikola Pantchev." Gießen : VVB Laufersweiler, 2006. http://d-nb.info/988660539/34.

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49

Moustafa, Amr [Verfasser], and Christian [Akademischer Betreuer] Betzel. "Structural and Functional Analyses of Secretory and Excretory Proteins from Onchocerca volvulus as Basis for Rational Drug Design / Amr Moustafa. Betreuer: Christian Betzel." Hamburg : Staats- und Universitätsbibliothek Hamburg, 2016. http://d-nb.info/1098428927/34.

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Moustafa, Amr Verfasser], and Christian [Akademischer Betreuer] [Betzel. "Structural and Functional Analyses of Secretory and Excretory Proteins from Onchocerca volvulus as Basis for Rational Drug Design / Amr Moustafa. Betreuer: Christian Betzel." Hamburg : Staats- und Universitätsbibliothek Hamburg, 2016. http://nbn-resolving.de/urn:nbn:de:gbv:18-78577.

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You might also be interested in the bibliographies on the topic 'Onchocerca' for other source types:
Journal articles
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