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Journal articles on the topic 'Onchocerca'

Author: Grafiati

Published: 4 June 2021

Last updated: 17 February 2022

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1

Richard-Lenoble, Dominique. "Onchocerca volvulus." EMC - Biologie Médicale 1, no. 1 (2006): 1–8. http://dx.doi.org/10.1016/s2211-9698(06)76283-5.

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2

Truant, Allan L., Irma Palazzo, Byungse Suh, and Francis Au. "Onchocerca volvulus." Clinical Microbiology Newsletter 20, no. 4 (1998): 29–30. http://dx.doi.org/10.1016/s0196-4399(01)80048-9.

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3

Hall, Laurie R., and Eric Pearlman. "Pathogenesis of Onchocercal Keratitis (River Blindness)." Clinical Microbiology Reviews 12, no. 3 (1999): 445–53. http://dx.doi.org/10.1128/cmr.12.3.445.

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SUMMARY Onchocerciasis is a major cause of blindness. Although the World Health Organization has been successful in reducing onchocerciasis as a public health problem in parts of West Africa, there remain an estimated 17 million people infected with Onchocerca volvulus, the parasite that causes this disease. Ocular pathology can be manifested in any part of the eye, although disease manifestations are frequently characterized as either posterior or anterior eye disease. This review focuses on onchocerca-mediated keratitis that results from an inflammatory response in the anterior portion of th

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4

Guderian, Ronald H., Mariela Anselmi, Philip J. Cooper, and Martha E. Chico. "Macrofilaricidal effects of chloroquine on adult Onchocerca volvulus by local infiltration of palpable onchocercal nodules." Revista da Sociedade Brasileira de Medicina Tropical 30, no. 6 (1997): 469–73. http://dx.doi.org/10.1590/s0037-86821997000600005.

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The macrofilaricidal effects of local infiltration of high concentrations of chloroquine into the capsule of onchocercal nodules on adult worms of Onchocerca volvulus was determined. Six weeks post infiltration, histological examination of single nodules showed all adult worms to be dead. With nodule conglomerates, there was localized action of chloroquine only on the adult worms in the infiltrated nodule, with no diffusion of the drug to adjacent nodules. Chloroquine infiltration of young, recently formed nodules to reduce the adult worm load of infected individuals may be an alternative meth

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5

Dunn, T. S., P. S. Raines, J. Barrett, and P. E. Butterworth. "Carbohydrate metabolism in Onchocerca gutturosa and Onchocerca lienalis (Nematoda:Filarioidea)." International Journal for Parasitology 18, no. 1 (1988): 21–26. http://dx.doi.org/10.1016/0020-7519(88)90031-8.

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6

Agatsuma, Takeshi, and Mamoru Ito. "Isozyme Study of Onchocerca volvulus and Onchocerca gutturosa in Guatemala." Journal of Parasitology 71, no. 3 (1985): 370. http://dx.doi.org/10.2307/3282023.

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7

Shah, Jyotsna S., Willy F. Piessens, Dyann F. Wirth, and Marc Karam. "Characterization of an Onchocerca-Specific DNA Clone from Onchocerca Volvulus." American Journal of Tropical Medicine and Hygiene 37, no. 2 (1987): 376–84. http://dx.doi.org/10.4269/ajtmh.1987.37.376.

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8

Brydon, L. J., G. W. Gooday, L. H. Chappell, and T. P. King. "Chitin in egg shells of Onchocerca gibsoni and Onchocerca volvulus." Molecular and Biochemical Parasitology 25, no. 3 (1987): 267–72. http://dx.doi.org/10.1016/0166-6851(87)90090-9.

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9

Carlow, C. K. S., and A. E. Bianco. "Resistance to Onchocerca lienalis microfilariae in mice conferred by egg antigens of homologous and heterologous Onchocerca species." Parasitology 94, no. 3 (1987): 485–96. http://dx.doi.org/10.1017/s0031182000055839.

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Embryonic stages of various Onchocerca species have been used to stimulate resistance in CBA mice to challenge injections with the microfilariae of Onchocerca lienalis. Comparable levels of resistance to challenge (29–37% reductions) were conferred by living, freeze-killed, or sonicated organisms administered with Freunds‘ Complete Adjuvant (FCA). Antigens extracted in saline, or with the detergent sodium deoxycholate, were also protective. Adjuvants enhanced the protective effect, particularly FCA (78% reduction), Freunds‘ Incomplete Adjuvant (74% reduction), aluminium hydroxide (70% reductio

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10

Koehsler, Martina, Afschin Soleiman, Horst Aspöck, Herbert Auer, and Julia Walochnik. "Onchocerca jakutensisFilariasis in Humans." Emerging Infectious Diseases 13, no. 11 (2007): 1749–52. http://dx.doi.org/10.3201/eid1311.070017.

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11

García-Dihinx Villanova, J., P. Betrián Blasco, F. De Juan Martín, M. Bouthelier Moreno, M. aC Marín Bravo, and M. aJ Revillo Pinilla. "Parasitosis por Onchocerca volvulus." Anales de Pediatría 55, no. 5 (2001): 486–87. http://dx.doi.org/10.1016/s1695-4033(01)77881-2.

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12

Williams, J. F., M. El Khalifa, C. D. Mackenzie, and B. Sisley. "Antigens of Onchocerca volvulus." Clinical Infectious Diseases 7, no. 6 (1985): 831–36. http://dx.doi.org/10.1093/clinids/7.6.831.

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13

Lackey, Angela, Eric R. James, Judy A. Sakanari, et al. "Extracellular proteases of Onchocerca." Experimental Parasitology 68, no. 2 (1989): 176–85. http://dx.doi.org/10.1016/0014-4894(89)90095-7.

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14

Townson, Simon, and Senyo K. Tagboto. "In Vitro Cultivation and Development of Onchocerca volvulus and Onchocerca lienalis Microfilariae." American Journal of Tropical Medicine and Hygiene 54, no. 1 (1996): 32–37. http://dx.doi.org/10.4269/ajtmh.1996.54.32.

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15

WAHL, G., P. ENYONG, A. NGOSSO, et al. "Onchocerca ochengi: epidemiological evidence of cross-protection against Onchocerca volvulus in man." Parasitology 116, no. 4 (1998): 349–62. http://dx.doi.org/10.1017/s003118209700228x.

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In North Cameroon, the vector of Onchocerca volvulus (causative agent of human onchocerciasis) also transmits 2 filariae of animals: O. ochengi from cattle and O. ramachandrini from wart hogs. In order to assess the qualitative and quantitative roles of these ‘animal filariae’ in the epidemiology of O. volvulus, the transmission of the 3 parasites was measured in 2 villages and related to the endemicity of human onchocerciasis. In Galim, a cattle-farming Guinea savanna village where wild animals are rare, the overwhelming majority of all filarial infections found in the Simulium damnosum s.l.

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16

CABRERA, Z., and R. PARKHOUSE. "Identification of antigens of Onchocerca volvulus and Onchocerca gibsoni for diagnostic use." Molecular and Biochemical Parasitology 20, no. 3 (1986): 225–31. http://dx.doi.org/10.1016/0166-6851(86)90102-7.

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17

Mirzaei, Mohammad, Younes Ghahvei, Emilie Lefoulon, et al. "Morphological and molecular characterization of Onchocerca fasciata (Nematoda, Onchocercidae) from dromedary camels (Camelus dromedarius) in Iran." Parasite 25 (2018): 50. http://dx.doi.org/10.1051/parasite/2018045.

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Skin nodules of Onchocerca fasciata Railliet and Henry, 1910 (Spirurida, Onchocercidae) are a common finding in dromedary camels, though with a minimal clinical impact. There is little information about the morphology, molecular make-up and pathological impact of this parasite. Onchocerca fasciata nodules (1.3–2.1 cm in diameter and 509–841 mg in weight) were detected on the neck region in 31.5% of dromedary camels examined in Kerman province, southeastern Iran. Of 38 isolated nodules, only 23 (60.5%) contained viable worms. Measurement and morphological analyses were performed on isolated fem

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18

Maia, Carla, Giada Annoscia, Maria Stefania Latrofa, et al. "Onchocerca lupiNematode in Cat, Portugal." Emerging Infectious Diseases 21, no. 12 (2015): 2252–54. http://dx.doi.org/10.3201/eid2112.150061.

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19

Sallo, Ferenc, Mark L. Eberhard, Eva Fok, Ferenc Baska, and Istvan Hatvani. "Zoonotic intravitreal Onchocerca in Hungary." Ophthalmology 112, no. 3 (2005): 502–4. http://dx.doi.org/10.1016/j.ophtha.2004.10.036.

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20

Unnasch, Thomas R., and Steven A. Williams. "The genomes of Onchocerca volvulus." International Journal for Parasitology 30, no. 4 (2000): 543–52. http://dx.doi.org/10.1016/s0020-7519(99)00184-8.

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21

Taylor, David W., Judith M. Goddard, and John E. McMahon. "Surface components of Onchocerca volvulus." Molecular and Biochemical Parasitology 18, no. 3 (1986): 283–300. http://dx.doi.org/10.1016/0166-6851(86)90086-1.

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22

Copeman, D. B. "Molecular variation in Onchocerca spp." Acta Tropica 53, no. 3-4 (1993): 307–17. http://dx.doi.org/10.1016/0001-706x(93)90036-b.

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23

Procunier, W. S., and H. Hirai. "The chromosomes of Onchocerca volvulus." Parasitology Today 2, no. 11 (1986): 307–9. http://dx.doi.org/10.1016/0169-4758(86)90125-0.

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24

Schulz-Key, H., and M. Karam. "Periodic reproduction of onchocerca volvulus." Parasitology Today 2, no. 10 (1986): 284–86. http://dx.doi.org/10.1016/0169-4758(86)90138-9.

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25

Shintouo, Cabirou Mounchili, Joel Ebai Nguve, Fru Bertha Asa, et al. "Entomological Assessment of Onchocerca Species Transmission by Black Flies in Selected Communities in the West Region of Cameroon." Pathogens 9, no. 9 (2020): 722. http://dx.doi.org/10.3390/pathogens9090722.

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The enormity of the public health burden of onchocerciasis motivated the creation of various large-scale control programs that have depended principally on mass treatment of endemic communities with ivermectin for the elimination of the disease. Parasitological evaluation of Onchocerca species in the West Region of Cameroon indicates significant progress in the interruption of parasite transmission in some communities under ivermectin treatment. However, to verify the complete elimination of onchocerciasis, entomological assessment through O-150 PCR poolscreen of black flies is mandatory. Thus

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26

Cambra-Pellejà, Maria, Javier Gandasegui, Rafael Balaña-Fouce, José Muñoz, and María Martínez-Valladares. "Zoonotic Implications of Onchocerca Species on Human Health." Pathogens 9, no. 9 (2020): 761. http://dx.doi.org/10.3390/pathogens9090761.

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The genus Onchocerca includes several species associated with ungulates as hosts, although some have been identified in canids, felids, and humans. Onchocerca species have a wide geographical distribution, and the disease they produce, onchocerciasis, is generally seen in adult individuals because of its large prepatency period. In recent years, Onchocerca species infecting animals have been found as subcutaneous nodules or invading the ocular tissues of humans; the species involved are O. lupi, O. dewittei japonica, O. jakutensis, O. gutturosa, and O. cervicalis. These findings generally invo

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27

de Almeida, Marcos, Fernanda S. Nascimento, Blaine A. Mathison, et al. "Duplex Real-Time PCR Assay for Clinical Differentiation of Onchocerca lupi and Onchocerca volvulus." American Journal of Tropical Medicine and Hygiene 103, no. 4 (2020): 1556–62. http://dx.doi.org/10.4269/ajtmh.20-0113.

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28

ACHUKWI, M. D., W. HARNETT, P. ENYONG, and A. RENZ. "Successful vaccination against Onchocerca ochengi infestation in cattle using live Onchocerca volvulus infective larvae." Parasite Immunology 29, no. 3 (2007): 113–16. http://dx.doi.org/10.1111/j.1365-3024.2006.00917.x.

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29

Jaleta, Tegegn G., Christian Rödelsperger, Babette Abanda, et al. "Full mitochondrial and nuclear genome comparison confirms that Onchocerca sp. “Siisa” is Onchocerca ochengi." Parasitology Research 117, no. 4 (2018): 1069–77. http://dx.doi.org/10.1007/s00436-018-5783-0.

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30

&NA;. "EFFECT OF SINGLE-DOSE IVERMECTIN THERAPY ON HUMAN ONCHOCERCA VOLVULUS INFECTION WITH ONCHOCERCAL OCULAR INVOLVEMENT." International Ophthalmology Clinics 30, no. 1 (1990): 27. http://dx.doi.org/10.1097/00004397-199030010-00012.

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31

&NA;. "EFFECT OF SINGLE-DOSE IVERMECTIN THERAPY ON HUMAN ONCHOCERCA VOLVULUS INFECTION WITH ONCHOCERCAL OCULAR INVOLVEMENT." International Ophthalmology Clinics 34, no. 3 (1994): 27. http://dx.doi.org/10.1097/00004397-199400000-00012.

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32

Newland, H. S., A. T. White, B. M. Greene, et al. "Effect of single-dose ivermectin therapy on human Onchocerca volvulus infection with onchocercal ocular involvement." British Journal of Ophthalmology 72, no. 8 (1988): 561–69. http://dx.doi.org/10.1136/bjo.72.8.561.

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33

Asaduzzaman, M., MAA Mamun, M. Anisuzzaman, et al. "Epidemiology and pathology of onchocercosis of cattle in Bangladesh." Progressive Agriculture 26, no. 2 (2015): 147–54. http://dx.doi.org/10.3329/pa.v26i2.25976.

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Onchocercosis is a parasitic disease caused by the different species of nematodes belonging to the genus Ochocerca affecting both humans and animals. Ochocerca armillta, O. gutturosa and O. gibsoni affect mainly cattle, and also buffaloes. Here, we studied epidemio-pathology and vector flies of onchocercosis in cattle in Bangladesh. Out of 310 animals examined, 163 (52.6%) were infected with different species of Onchocerca. Three species of Onchocerca, namely, Onchocerca armillata (24.8%), Onchocerca gutturosa (24.7%) and Onchocerca gibsoni (13.3%) were identified. We recovered O. armillata on

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34

Vuong, P. N., S. Wanji, J. Prod'Hon, and O. Bain. "Nodules sous-cutanés et lésions cutanées engendrés par diverses onchocerques chez des bovins africains." Revue d’élevage et de médecine vétérinaire des pays tropicaux 47, no. 1 (1994): 47–51. http://dx.doi.org/10.19182/remvt.9131.

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Des nodules sous-cutanés et de la peau ombilicale sont prélevés sur 6 Bos indicus onchocerquiens au Cameroun, pour l'étude anatomopathologiq ue. Les nodules à Onchocerca ochengi et Onchocerca dukei ont la même structure que celle des nodules à Onchocerca volvulus de l'homme; ce sont des pseudo-kystes inflammatoire contenant souvent une fillaire femelle. La composante cellulaire de la paroi du pseudo-kyste permet de classer les nodules en trois types : nodule "jeune", nodule "évolué" et nodule "ancien". Le nodule est circonscrit par des vaisseaux dont la lumière contient parfois des microfilair

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35

Bah, Germanus S., Sebastian Schneckener, Steffen R. Hahnel, et al. "Emodepside targets SLO-1 channels of Onchocerca ochengi and induces broad anthelmintic effects in a bovine model of onchocerciasis." PLOS Pathogens 17, no. 6 (2021): e1009601. http://dx.doi.org/10.1371/journal.ppat.1009601.

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Onchocerciasis (river blindness), caused by the filarial worm Onchocerca volvulus, is a neglected tropical disease mostly affecting sub-Saharan Africa and is responsible for >1.3 million years lived with disability. Current control relies almost entirely on ivermectin, which suppresses symptoms caused by the first-stage larvae (microfilariae) but does not kill the long-lived adults. Here, we evaluated emodepside, a semi-synthetic cyclooctadepsipeptide registered for deworming applications in companion animals, for activity against adult filariae (i.e., as a macrofilaricide). We demonstrate

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36

Marquart, K. H., K. Brandes, S. Kunder, L. Jennen, and E. H. Schäffer. "Okulare Onchozerkose bei einem Hund." Tierärztliche Praxis Ausgabe K: Kleintiere / Heimtiere 34, no. 03 (2006): 178–84. http://dx.doi.org/10.1055/s-0037-1622529.

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Zusammenfassung Gegenstand und Ziel: Das linke Auge einer vierjährigen, ein halbes Jahr zuvor aus Griechenland in die Schweiz eingeführten Mischlingshündin wurde wegen eines Exophthalmus bei Verdacht auf retrobulbären Abszess enukleiert und histologisch untersucht. Material und Methoden: Schnitte des formalinfixierten Auges wurden konventionell in Paraffin eingebettet. Histologisch fielen im periokularen Bindegewebe zahlreiche Parasitenanschnitte (Nematoden?) auf, die Anlass zu einer parasitologischen Untersuchung von Wurmfragmenten aus fixiertem Restgewebe gaben. Zudem erfolgte eine elektrone

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37

Beaver, P. C., H. Yoshimura, S. Takayasu, H. Hashimoto, and M. D. Little. "Zoonotic Onchocerca in a Japanese Child." American Journal of Tropical Medicine and Hygiene 40, no. 3 (1989): 298–300. http://dx.doi.org/10.4269/ajtmh.1989.40.298.

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38

Nava, Victor E., and Adetoun A. Ejilemele. "Onchocerca volvulus Mimicking Metastatic Breast Carcinoma." American Journal of Tropical Medicine and Hygiene 102, no. 3 (2020): 487–88. http://dx.doi.org/10.4269/ajtmh.19-0740.

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39

Harnett, William. "DNA-based detection of Onchocerca volvulus." Transactions of the Royal Society of Tropical Medicine and Hygiene 96 (April 2002): S231—S234. http://dx.doi.org/10.1016/s0035-9203(02)90081-7.

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40

Strotel, G., A. Bokhof, and J. C. W. Comley. "Viability of Onchocerca volvulus in vitro." Parasitology 107, no. 2 (1993): 175–82. http://dx.doi.org/10.1017/s0031182000067287.

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SUMMARYThe use of a selective schedule of tests to identify a viable population of isolated adult Onchocerca volvulus (Nematoda: Filarioidea) has been investigated in a large worm population. The study was initiated to develop methodology appropriate to test new candidate macrofilaricides for their in vitro activity against O. volvulus. After removal from the host the viability of isolated intact parasites was estimated by assessing the motility indices of male worms, and the colorimetric quantification of the reduction of the bioreducible tetrazolium reagent XTT and lactate output by female w

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41

HOLDSWORTH, P. A., and D. E. MOORHOUSE. "Onchocerca gutturosa in an Australian camel." Australian Veterinary Journal 62, no. 6 (1985): 201–2. http://dx.doi.org/10.1111/j.1751-0813.1985.tb07300.x.

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42

Holdsworth, P. A. "Scanning electron microscopy of Onchocerca sweetae." International Journal for Parasitology 18, no. 4 (1988): 561–63. http://dx.doi.org/10.1016/0020-7519(88)90025-2.

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43

Unnasch, Thomas R., Charles R. Katholi, and Linda M. Coate. "Onchocerca volvulus: Frequency of codon usage." Experimental Parasitology 75, no. 4 (1992): 457–59. http://dx.doi.org/10.1016/0014-4894(92)90259-d.

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44

Zeng, Wenlin, and John E. Donelson. "The actin genes of Onchocerca volvulus." Molecular and Biochemical Parasitology 55, no. 1-2 (1992): 207–16. http://dx.doi.org/10.1016/0166-6851(92)90141-6.

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45

Unnasch, T. R. "DNA probes to identify Onchocerca volvulus." Parasitology Today 3, no. 12 (1987): 377–78. http://dx.doi.org/10.1016/0169-4758(87)90248-1.

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46

Erttmann, Klaus D., and Dietrich W. Büttner. "Immunohistological studies on Onchocerca volvulus paramyosin." Parasitology Research 105, no. 5 (2009): 1371–74. http://dx.doi.org/10.1007/s00436-009-1566-y.

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47

Lal, P. G., and E. R. James. "Onchocerca retinol- and ivermectin-binding protein activity." Parasitology 112, no. 2 (1996): 221–25. http://dx.doi.org/10.1017/s0031182000084791.

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SummaryThe presence of retinol-binding protein (RBP) activity in Onchocerca cervicalis adult worms and interaction with ivermectin has been studied using high pressure size exclusion chromatography (HPSEC). Four distinct peaks of [3H]-retinol incorporation were obtained corresponding to approximate molecular weights of 150, 67, 19·7 and 4–6 kDa, the 2 smaller Mr peaks accounting for most of the binding activity. Competition for binding using non-labelled retinol at 200-fold molar excess indicated that specific binding of retinol occurred only to the 19–7 kDa fraction. Competition by ivermectin

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48

HAGEN, H. E., and S. L. KLÄGER. "Integrin-like RGD-dependent cell adhesion mechanism is involved in the rapid killing of Onchocerca microfilariae during early infection of Simulium damnosum s.l." Parasitology 122, no. 4 (2001): 433–38. http://dx.doi.org/10.1017/s0031182001007545.

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Injection trials with compatible and non-compatible Onchocerca species into S. damnosum s.l., the vector of human and bovine onchocerciasis, demonstrated that the rapid killing of microfilariae within the blackfly's haemocoel is species specific. In the presence of the peptide RGDS as a blocking agent for integrin-like receptors of haemocytes, the survival of O. ochengi microfilariae in its natural intermediate host was significantly increased. This increased survival 24 h p.i. correlated with a significant decrease of apoptosis levels in the microfilariae following a 2 h exposure to the haemo

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49

Lucius, R., H. Schulz-Key, D. W. Büttner, et al. "Characterization of an immunodominant Onchocerca volvulus antigen with patient sera and a monoclonal antibody." Journal of Experimental Medicine 167, no. 4 (1988): 1505–10. http://dx.doi.org/10.1084/jem.167.4.1505.

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Adult Onchocerca voluvlus and infective larvae, but not microfilariae contain an immunodominant antigen (33,000 and 21,000 Mr in females, 39,000, 33,000, and 21,000 Mr in males, 133,000 Mr in infective larvae) which is recognized by an Onchocerca-specific mAb. The component is part of the reproductive organs and muscles. 96.2% of onchocerciasis sera contained antibodies detectable by immunoblotting against it. Antigen purified by immunoaffinity chromatography was specifically recognized in immunoblots by onchocerciasis sera, but not by sera from other filarial infections. The high immunogenici

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50

Sréter-Lancz, Z., Z. Széll, and T. Sréter. "Molecular genetic comparison of Onchocerca sp. infecting dogs in Europe with other spirurid nematodes including Onchocerca lienalis." Veterinary Parasitology 148, no. 3-4 (2007): 365–70. http://dx.doi.org/10.1016/j.vetpar.2007.06.021.

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