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1

Travers, Helen. Oncogene regulation of gene expression. Manchester: University of Manchester, 1996.

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2

Morgan, James I. Proto-Oncogene expression in the nervous /system. Amsterdam: Published by Elsevier for the Foundation for the study of the Nervous System (FESN), 1991.

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3

Rowley, S. Nuclear oncogene expression in the prognosis of colorectal cancer. Birmingham: University of Birmingham, 1990.

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4

Detta, Allah. Proliferative potential and proto-oncogene expression in human meningioma. Birmingham: Universityof Birmingham, 1993.

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5

Darley, Richard Lawrence. Modulation of major histocompatibility antigen expression by the ras oncogene in murine fibroblast cells. [s.l.]: typescript, 1992.

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6

Jordan, Richard. A study of c-erbB-2 oncogene expression in salivary gland neoplasms by in situ hybridisation. Ottawa: National Library of Canada = Bibliothèque nationale du Canada, 1993.

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7

Jordan, Richard. A study of c-erb B-2 oncogene expression in salivary gland neoplasms by in situ hybridisation. [Toronto: Faculty of Dentistry, University of Toronto], 1992.

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8

Chapman, Rachel Susan. Investigation into the relationship between expression of the activated Abelson oncogene, drug sensitivity and suppression of apoptosis in chronic myeloid Leukaemia. Manchester: University of Manchester, 1995.

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9

rdh-Nilsson, Anna Hultga. Oncogenes and second messengers in the regulation of smooth muscle cell growth and differentiation. Stockholm: Kongl. Carolinska Medico Chirurgiska Institutet, 1991.

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10

David, Puett, ed. Advances in gene technology: Molecular biology of the endocrine system : proceedings of the Eighteenth Miami Winter Symposium, Miami, Florida, U.S.A., February 3-7, 1986. Cambridge: Cambridge University Press, 1986.

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11

Miami Winter Symposium (18th 1986). Advances in gene technology: Molecular biology of the endocrine system : proceedings of the Eighteenth Miami Winter Symposium, Miami, Florida, USA, February 3-7, 1986. Cambridge: Cambridge University Press, 1986.

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12

1942-, Harris Stephen E., and Mansson Per-Erik, eds. Cellular factors in development and differentiation: Embryos, teratocarcinomas, and differentiated tissues : proceedings of the Third International Symposium on Cellular Endocrinology, held at Lake Placid, New York, August 30-September 2, 1987. New York: Liss, 1988.

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13

Triton Biosciences-UCLA Symposium (1986 Steamboat Springs, Colo.). Growth factors, tumor promoters, and cancer genes: Proceedings of a Triton Biosciences-UCLA Symposium held in Steamboat Springs, Colorado, April 6-13, 1986. Edited by Colburn Nancy H, Moses Harold L, and Stanbridge Eric J. New York: Liss, 1988.

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14

E, Celis J., Graessmann A, NATO Advanced Study Institute, Federation of European Biochemical Societies., Fundáçao Calouste Gulbenkian, and North Atlantic Treaty Organization. Scientific Affairs Division., eds. Cell transformation. New York: Plenum Press, 1985.

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15

International Conference on Gene Regulation, Oncogenesis, and AIDS (1st 1989 Loutráki, Greece). Oncogenesis: Oncogenes in signal transduction and cell proliferation : papers delivered at the First International Conference on Gene Regulation, Oncogenesis, and AIDS, Loutraki, Greece, September 15-21, 1989. Edited by Papas Takis S. Woodlands, Tex: Portfolio Pub. Co., 1990.

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16

H, Colburn Nancy, Moses Harold L, and Stanbridge Eric J, eds. Growth factors, tumor promoters and cancer genes: Proceedings of a Triton Biosciences UCLA Symposium held in Steamboat Springs, Colorado, April 6-13, 1986. New York: Liss, 1988.

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17

L, Moses Harold, Lengyel Peter 1929-, Stiles Charles D, and Genentech Inc, eds. Growth inhibitory and cytotoxic polypeptides ; proceedings of a Genentech-Smith, Kline & French-Triton Biosciences-UCLA Symposium held in Keystone, Colorado, January 24-30, 1988. New York: A.R. Liss, 1989.

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18

Trimble, William Stanley. Expression of the "ras" oncogene and cellular transformation. 1987.

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19

Wingett, Denise G. Characterization of post-transcriptional mechanisms involved in the expression of the pim-1 proto-oncogene. 1991.

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20

E, Angel Peter, and Herrlich Peter 1940-, eds. The fos and jun families of transcription factors. Boca Raton: CRC Press, 1994.

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21

Merl, Dan, Joseph Lucas, Joseph Nevins, Haige Shen, and Mike West. Trans-study projection of genomic biomarkers in analysis of oncogene deregulation and breast cancer. Edited by Anthony O'Hagan and Mike West. Oxford University Press, 2018. http://dx.doi.org/10.1093/oxfordhb/9780198703174.013.6.

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This article focuses on the use of Bayesian concepts and methods in the trans-study projection of genomic biomarkers for the analysis of oncogene deregulation in breast cancer. The objective of the study is to determine the extent to which patterns of gene expression associated with experimentally induced oncogene pathway deregulation can be used to investigate oncogene pathway activity in real human cancers. This is often referred to as the in vitro to in vivo translation problem, which is addressed using Bayesian sparse factor regression analysis for model-based translation and refinement of in vitro generated signatures of oncogene pathway activity into the domain of human breast tumour tissue samples. The article first provides an overview of the role of oncogene pathway deregulation in human cancers before discussing the details of modelling and data analysis. It then considers the findings based on biological evaluation and Bayesian pathway annotation analysis.
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22

Regenstreif, Leonora Julie *. Expression of the C-fms proto-oncogene and of the cytokine, CSF-1 during mouse embrogenesis. 1989.

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23

Growth regulation and proto-oncogene expression in human multiple myeloma cell lines in vitro (Acta Universitatis Upsaliensis). Dept. of Pathology, University of Uppsala, 1991.

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24

A, Khan Sohaib, and Stancel George M, eds. Protooncogenes and growth factors in steroid hormone induced growth and differentiation. Boca Raton: CRC Press, 1994.

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25

(Editor), M. Yaniv, and J. Ghysdael (Editor), eds. Oncogenes as Transcriptional Regulators: Volume 1: Retroviral Oncogenes (Progress in Gene Expression). Birkhauser, 1997.

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26

A, Sharp Phillip, and Bristol-Myers Squibb Symposium on Cancer Research (14th : 1990 : Massachusetts Institute of Technology), eds. Nuclear processes and oncogenes. San Diego: Academic Press, 1992.

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27

Gregory, Bock, Marsh Joan, and Symposium on Proto-oncogenes in Cell Development (1989 : Ciba Foundation), eds. Proto-oncogenes in cell development. Chichester: Wiley, 1990.

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28

W, Alt Frederick, Harlow Edward, Ziff Edward, and Cold Spring Harbor Laboratory, eds. Nuclear oncogenes. Cold Spring Harbor, N.Y: Cold Spring Harbor Laboratory, 1987.

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29

Luigi, Frati, and Aaronson Stuart A. 1942-, eds. Pathology of gene expression. New York: Raven Press, 1989.

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30

(Editor), Stuart A. Aaronson, ed. Pathology of Gene Expression. Lippincott Williams & Wilkins, 1990.

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31

Patricia, Kahn, and Graf T, eds. Oncogenes and growth control. Berlin: Springer-Verlag, 1986.

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32

Expression Profiling of Human Tumors: Diagnostic and Research Applications. Humana Press, 2003.

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33

A, Marks Paul, Memorial Sloan-Kettering Cancer Center, Bristol-Myers Company, and Bristol-Myers Symposium on Cancer Research (7th : 1984 : Memorial Sloan-Kettering Cancer Center), eds. Genetics, cell differentiation, and cancer. Orlando: Academic Press, 1985.

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34

Gregory, Bock, Marsh Joan, and Ciba Foundation, eds. Genetic analysis of tumour suppression. Chichester: Wiley, 1989.

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35

Simone, Mocellin, ed. Microarray technology and cancer gene profiling. New York, N.Y: Kluwer Academic/Plenum Publishers, 2007.

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36

Mocellin, Simone. Microarray Technology and Cancer Gene Profiling. Springer, 2010.

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37

(Editor), F. J. Rauscher, and P. K. Vogt (Editor), eds. Chromosomal Translocations and Oncogenic Transcription Factors. Springer-Verlag Telos, 1997.

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38

Marc, Ladanyi, and Gerald William L, eds. Expression profiling of human tumors: Diagnostic and research applications. Totowa, N.J: Humana Press, 2003.

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39

Marc, Ladanyi, and Gerald William L, eds. Expression profiling of human tumors: Diagnostic and research applications. Totowa, N.J: Humana Press, 2003.

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40

Michael, Botchan, Grodzicker Terri, and Sharp Phillip A, eds. DNA tumor viruses: Control of gene expression and replication. Cold Spring Harbor, N.Y: Cold Spring Harbor Laboratory, 1986.

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41

(Editor), Enrico Mihich, and David Housman (Editor), eds. Cancer Genes: Functional Aspects (Pezcoller Foundation Symposia). Springer, 1997.

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42

Cancer Genes: Functional Aspects. Springer, 2011.

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43

Enrico, Mihich, Housman David E, and Pezcoller Symposium on Cancer Genes: Functional Aspects (7th. : 1995 : Trento, Italy), eds. Cancer genes: Functional aspects. New York: Plenum Press, 1996.

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44

Herrero, Rolando, and Raul Murillo. Cervical Cancer. Oxford University Press, 2017. http://dx.doi.org/10.1093/oso/9780190238667.003.0048.

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Cervical cancer is the fourth most common cancer in women worldwide, with more than 500,000 cases and 250,000 deaths per year. The disease is characterized by marked regional differences, with more than 80% of the cases and deaths occurring in developing countries. The etiology and natural history of the disease are very well studied, with persistent infection with one of thirteen human papillomavirus (HPV) types now considered to be a necessary cause. The molecular mechanisms have also been elucidated and are mediated mainly by the expression of viral oncogenes that interfere with cellular pathways. The two most common HPV types, namely HPV-16 and HPV-18, are associated with about 70% of all cases around the world. Immunologic (e.g., HIV infection), hormonal (e.g., high parity), environmental (e.g., smoking), and genetic (e.g., HLA type) cofactors determine the risk of persistence and cancer among women harboring HPV infection.
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45

Grodzicker, Terri, and Michael Botchan. DNA Tumor Viruses: Control of Gene Expression and Replication (Cancer Cells, 4). Cold Spring Harbor Laboratory Pr, 1986.

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46

Hendrix, Mary. Maspin (Medical Intelligence Unit, Unit 32). Eurekah.com, 2001.

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47

Hendrix, Mary. Maspin (Medical Intelligence Unit, Unit 32). Landes Bioscience, 2002.

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48

Cellular factors in development and differentiation: Embryos, teratocarcinomas, and differentiated tissues : Proceedings of the Third International Symposium ... in clinical and biological research). Liss, 1988.

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49

1932-, Friedman Robert M., Merigan Thomas C. 1934-, Sreevalsan T, Schering Corporation, and UCLA Symposium on Interferons as Cell Growth Inhibitors and Antitumor Factors (1986 : Steamboat Springs, Colo.), eds. Interferons as cell growth inhibitors and antitumor factors: Proceedings of a UCLA Symposium held in Steamboat Springs, Colorado, April 6-12, 1986. New York: Liss, 1986.

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50

P, Villarreal Luis, and ICN-UCI International Conference on Virology (1989 : Newport Beach, Calif.), eds. Common mechanisms of transformation by small DNA tumor viruses. Washington, DC: American Society for Microbiology, 1989.

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